locus-tag	class	description
E3G57_RS00015	COG0592	DNA-directed DNA polymerase activity
E3G57_RS00020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
E3G57_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E3G57_RS00030	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
E3G57_RS00035	COG0187	DNA topoisomerase II activity
E3G57_RS00120	COG2814	Major facilitator Superfamily
E3G57_RS00125	COG0583	DNA-binding transcription factor activity
E3G57_RS00140	COG0705	Rhomboid family
E3G57_RS00140	COG0457	Tetratricopeptide repeat
E3G57_RS00170	COG0515	serine threonine protein kinase
E3G57_RS00170	COG2815	serine threonine protein kinase
E3G57_RS00175	COG0515	serine threonine protein kinase
E3G57_RS00180	COG0768	penicillin binding
E3G57_RS00195	COG1716	ATPase activity
E3G57_RS00200	COG1716	ATPase activity
E3G57_RS00245	COG0754	glutathionylspermidine amidase activity
E3G57_RS00265	COG1309	transcriptional regulator
E3G57_RS00285	COG4842	Belongs to the WXG100 family
E3G57_RS00305	COG0590	tRNA wobble adenosine to inosine editing
E3G57_RS00315	COG0583	DNA-binding transcription factor activity
E3G57_RS00320	COG1643	Atp-dependent helicase
E3G57_RS00325	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS00355	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS00400	COG2072	flavoprotein involved in K transport
E3G57_RS00410	COG0346	lactoylglutathione lyase activity
E3G57_RS00415	COG1414	Transcriptional regulator
E3G57_RS00435	COG1053	succinate dehydrogenase
E3G57_RS00465	COG1785	Belongs to the alkaline phosphatase family
E3G57_RS00485	COG0070	glutamate synthase
E3G57_RS00485	COG0067	glutamate synthase
E3G57_RS00485	COG0069	glutamate synthase activity
E3G57_RS00515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E3G57_RS00515	COG1796	DNA polymerase
E3G57_RS00525	COG2072	flavoprotein involved in K transport
E3G57_RS00535	COG2124	cytochrome p450
E3G57_RS00580	COG2372	response to copper ion
E3G57_RS00630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3G57_RS00650	COG5002	protein histidine kinase activity
E3G57_RS00650	COG5001	Diguanylate cyclase
E3G57_RS00650	COG3447	MASE1 domain protein
E3G57_RS00660	COG1528	Iron-storage protein
E3G57_RS00665	COG1528	Iron-storage protein
E3G57_RS00695	COG0406	alpha-ribazole phosphatase activity
E3G57_RS00705	COG0028	Belongs to the TPP enzyme family
E3G57_RS00730	COG2072	flavoprotein involved in K transport
E3G57_RS00740	COG2072	flavoprotein involved in K transport
E3G57_RS00760	COG1285	pathogenesis
E3G57_RS00810	COG2146	nitrite reductase [NAD(P)H] activity
E3G57_RS00810	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3G57_RS00820	COG4133	protoheme IX ABC transporter activity
E3G57_RS00825	COG2070	2-Nitropropane dioxygenase
E3G57_RS00830	COG1942	4-Oxalocrotonate Tautomerase
E3G57_RS00835	COG0583	DNA-binding transcription factor activity
E3G57_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS00855	COG0204	Acyl-transferase
E3G57_RS00865	COG0561	phosphatase activity
E3G57_RS00885	COG1216	Glycosyl transferase, family 2
E3G57_RS00890	COG0671	phosphoesterase, PA-phosphatase related
E3G57_RS00895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
E3G57_RS00900	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
E3G57_RS00920	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
E3G57_RS00925	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS00930	COG3321	synthase
E3G57_RS00930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E3G57_RS00930	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E3G57_RS00935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E3G57_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS00990	COG0277	FAD linked oxidase domain protein
E3G57_RS01000	COG2376	Dihydroxyacetone kinase
E3G57_RS01005	COG2267	carboxylic ester hydrolase activity
E3G57_RS01010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3G57_RS01015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3G57_RS01030	COG0671	phosphoesterase, PA-phosphatase related
E3G57_RS01040	COG1216	Glycosyl transferase, family 2
E3G57_RS01120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E3G57_RS01125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3G57_RS01195	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS01210	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS01230	COG1174	glycine betaine transport
E3G57_RS01245	COG0287	Prephenate dehydrogenase
E3G57_RS01255	COG0590	tRNA wobble adenosine to inosine editing
E3G57_RS01280	COG0343	queuine tRNA-ribosyltransferase activity
E3G57_RS01290	COG0765	amino acid transport
E3G57_RS01295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E3G57_RS01300	COG1793	dna ligase
E3G57_RS01330	COG2271	Major facilitator Superfamily
E3G57_RS01335	COG0604	alcohol dehydrogenase
E3G57_RS01360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E3G57_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS01415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3G57_RS01440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E3G57_RS01450	COG0148	phosphopyruvate hydratase activity
E3G57_RS01480	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3G57_RS01495	COG1492	cobalamin metabolic process
E3G57_RS01520	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS01535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E3G57_RS01565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E3G57_RS01610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3G57_RS01620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E3G57_RS01650	COG2070	2-Nitropropane dioxygenase
E3G57_RS01685	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3G57_RS01690	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E3G57_RS01695	COG2971	BadF BadG BcrA BcrD
E3G57_RS01700	COG2814	Major facilitator Superfamily
E3G57_RS01720	COG3572	ergothioneine biosynthetic process
E3G57_RS01725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
E3G57_RS01730	COG0121	glutamine amidotransferase
E3G57_RS01735	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
E3G57_RS01740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E3G57_RS01770	COG2030	dehydratase
E3G57_RS01775	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS01780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3G57_RS01790	COG1695	Transcriptional regulator
E3G57_RS01800	COG0475	glutathione-regulated potassium exporter activity
E3G57_RS01800	COG0569	domain protein
E3G57_RS01820	COG0714	Associated with various cellular activities
E3G57_RS01860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3G57_RS01865	COG1074	ATP-dependent DNA helicase activity
E3G57_RS01870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E3G57_RS01880	COG2755	lipolytic protein G-D-S-L family
E3G57_RS01910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3G57_RS01915	COG1408	metallophosphoesterase
E3G57_RS01920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E3G57_RS01950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3G57_RS01990	COG0596	Alpha beta hydrolase
E3G57_RS01990	COG2945	thiolester hydrolase activity
E3G57_RS02005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3G57_RS02010	COG0747	negative chemotaxis
E3G57_RS02020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3G57_RS02080	COG4584	PFAM Integrase catalytic
E3G57_RS02120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3G57_RS02190	COG0582	viral genome integration into host DNA
E3G57_RS02235	COG2217	Heavy metal translocating P-type atpase
E3G57_RS02245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3G57_RS02305	COG2132	Multicopper oxidase
E3G57_RS02395	COG1695	Transcriptional regulator
E3G57_RS02400	COG0657	acetylesterase activity
E3G57_RS02405	COG1902	pentaerythritol trinitrate reductase activity
E3G57_RS02410	COG1205	dead DEAH box helicase
E3G57_RS02410	COG1111	helicase
E3G57_RS02415	COG1278	Cold shock
E3G57_RS02425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E3G57_RS02425	COG1754	DNA topoisomerase type I activity
E3G57_RS02585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E3G57_RS02620	COG2027	D-alanyl-D-alanine carboxypeptidase
E3G57_RS02650	COG1063	alcohol dehydrogenase
E3G57_RS02660	COG2267	carboxylic ester hydrolase activity
E3G57_RS02670	COG1309	transcriptional regulator
E3G57_RS02685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3G57_RS02730	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
E3G57_RS02740	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E3G57_RS02760	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
E3G57_RS02765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3G57_RS02805	COG4977	sequence-specific DNA binding
E3G57_RS02810	COG1194	a g-specific adenine glycosylase
E3G57_RS02820	COG1316	TRANSCRIPTIONal
E3G57_RS02830	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
E3G57_RS02840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3G57_RS02860	COG1329	Transcriptional regulator
E3G57_RS02865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
E3G57_RS02875	COG0215	cysteine-tRNA ligase activity
E3G57_RS02885	COG0584	glycerophosphoryl diester phosphodiesterase
E3G57_RS02895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3G57_RS02900	COG1120	ATPase activity
E3G57_RS02905	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3G57_RS02915	COG1309	transcriptional regulator
E3G57_RS02920	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS02935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3G57_RS02945	COG0346	lactoylglutathione lyase activity
E3G57_RS02985	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS02990	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS02995	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS03000	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS03005	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS03020	COG0183	Belongs to the thiolase family
E3G57_RS03050	COG1024	Enoyl-CoA hydratase
E3G57_RS03055	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS03060	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS03080	COG0183	Belongs to the thiolase family
E3G57_RS03090	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS03095	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS03100	COG2030	dehydratase
E3G57_RS03125	COG2030	dehydratase
E3G57_RS03130	COG1053	succinate dehydrogenase
E3G57_RS03140	COG3971	2-oxopent-4-enoate hydratase activity
E3G57_RS03180	COG0651	ATP synthesis coupled electron transport
E3G57_RS03190	COG2111	Na H antiporter
E3G57_RS03190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3G57_RS03195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3G57_RS03215	COG0647	UMP catabolic process
E3G57_RS03250	COG4221	oxidoreductase activity
E3G57_RS03270	COG0459	protein refolding
E3G57_RS03285	COG0714	Associated with various cellular activities
E3G57_RS03335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E3G57_RS03350	COG4842	Belongs to the WXG100 family
E3G57_RS03395	COG0745	RESPONSE REGULATOR receiver
E3G57_RS03400	COG5002	protein histidine kinase activity
E3G57_RS03400	COG5000	phosphorelay sensor kinase activity
E3G57_RS03405	COG0537	adenosine 5'-monophosphoramidase activity
E3G57_RS03410	COG0697	spore germination
E3G57_RS03420	COG0596	Alpha beta hydrolase
E3G57_RS03450	COG0436	Aminotransferase
E3G57_RS03460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E3G57_RS03480	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS03485	COG0477	Major facilitator Superfamily
E3G57_RS03490	COG0386	Belongs to the glutathione peroxidase family
E3G57_RS03500	COG3573	Dehydrogenase
E3G57_RS03510	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3G57_RS03525	COG2837	iron assimilation
E3G57_RS03530	COG1362	aminopeptidase activity
E3G57_RS03605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3G57_RS03615	COG0601	transmembrane transport
E3G57_RS03620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3G57_RS03655	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
E3G57_RS03665	COG0354	folic acid binding
E3G57_RS03710	COG2897	thiosulfate sulfurtransferase activity
E3G57_RS03730	COG0745	RESPONSE REGULATOR receiver
E3G57_RS03750	COG0581	inorganic phosphate transmembrane transporter activity
E3G57_RS03755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E3G57_RS03760	COG0604	alcohol dehydrogenase
E3G57_RS03815	COG1250	3-hydroxyacyl-CoA dehydrogenase
E3G57_RS03840	COG0697	spore germination
E3G57_RS03860	COG0442	prolyl-tRNA aminoacylation
E3G57_RS03865	COG2814	Major facilitator Superfamily
E3G57_RS03920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E3G57_RS03925	COG1061	Type III restriction enzyme res subunit
E3G57_RS03930	COG1002	Type II restriction enzyme, methylase subunits
E3G57_RS03995	COG0436	Aminotransferase
E3G57_RS04015	COG0531	amino acid
E3G57_RS04020	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
E3G57_RS04025	COG1012	belongs to the aldehyde dehydrogenase family
E3G57_RS04035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3G57_RS04045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3G57_RS04050	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS04055	COG1012	belongs to the aldehyde dehydrogenase family
E3G57_RS04060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E3G57_RS04075	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS04105	COG1024	Enoyl-CoA hydratase
E3G57_RS04150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E3G57_RS04155	COG0657	acetylesterase activity
E3G57_RS04175	COG0183	Belongs to the thiolase family
E3G57_RS04190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3G57_RS04210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3G57_RS04250	COG4584	PFAM Integrase catalytic
E3G57_RS04290	COG1061	Type III restriction enzyme res subunit
E3G57_RS04330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E3G57_RS04355	COG1278	Cold shock
E3G57_RS04395	COG2814	Major facilitator Superfamily
E3G57_RS04470	COG1764	response to oxidative stress
E3G57_RS04475	COG1846	Transcriptional regulator
E3G57_RS04480	COG1216	Glycosyl transferase, family 2
E3G57_RS04485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
E3G57_RS04485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
E3G57_RS04515	COG0259	pyridoxamine-phosphate oxidase activity
E3G57_RS04525	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS04530	COG5651	PPE family
E3G57_RS04560	COG4977	sequence-specific DNA binding
E3G57_RS04585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS04595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3G57_RS04605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
E3G57_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS04615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3G57_RS04620	COG0545	Peptidyl-prolyl cis-trans isomerase
E3G57_RS04640	COG2072	flavoprotein involved in K transport
E3G57_RS04660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E3G57_RS04665	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
E3G57_RS04710	COG1012	belongs to the aldehyde dehydrogenase family
E3G57_RS04725	COG3022	response to hydroperoxide
E3G57_RS04735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3G57_RS04770	COG1309	transcriptional regulator
E3G57_RS04800	COG1393	Belongs to the ArsC family
E3G57_RS04845	COG0183	Belongs to the thiolase family
E3G57_RS04890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3G57_RS04930	COG0438	transferase activity, transferring glycosyl groups
E3G57_RS04935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3G57_RS04940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3G57_RS05000	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
E3G57_RS05005	COG1846	Transcriptional regulator
E3G57_RS05025	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
E3G57_RS05055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3G57_RS05065	COG2326	polyphosphate kinase activity
E3G57_RS05085	COG0523	cobalamin synthesis protein
E3G57_RS05090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E3G57_RS05095	COG0235	Class ii aldolase
E3G57_RS05100	COG1396	sequence-specific DNA binding
E3G57_RS05105	COG0166	Belongs to the GPI family
E3G57_RS05150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS05210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E3G57_RS05240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3G57_RS05245	COG0521	Mo-molybdopterin cofactor biosynthetic process
E3G57_RS05245	COG0315	cyclic pyranopterin monophosphate synthase activity
E3G57_RS05280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3G57_RS05285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E3G57_RS05380	COG2235	arginine
E3G57_RS05395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3G57_RS05410	COG1252	NADH dehydrogenase
E3G57_RS05420	COG0084	hydrolase, TatD family'
E3G57_RS05425	COG3583	domain protein
E3G57_RS05440	COG0515	serine threonine protein kinase
E3G57_RS05440	COG2815	serine threonine protein kinase
E3G57_RS05460	COG0456	acetyltransferase
E3G57_RS05460	COG1846	Transcriptional regulator
E3G57_RS05465	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
E3G57_RS05470	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS05485	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
E3G57_RS05520	COG1309	transcriptional regulator
E3G57_RS05565	COG3956	TIGRFAM MazG family protein
E3G57_RS05580	COG2837	iron assimilation
E3G57_RS05585	COG2822	iron ion transport
E3G57_RS05620	COG0596	Alpha beta hydrolase
E3G57_RS05645	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS05655	COG0427	acetyl-CoA hydrolase
E3G57_RS05710	COG1846	Transcriptional regulator
E3G57_RS05725	COG1024	Enoyl-CoA hydratase
E3G57_RS05750	COG0183	Belongs to the thiolase family
E3G57_RS05755	COG2755	lipolytic protein G-D-S-L family
E3G57_RS05760	COG0657	acetylesterase activity
E3G57_RS05770	COG1714	RDD family
E3G57_RS05785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E3G57_RS05805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E3G57_RS05815	COG1331	Highly conserved protein containing a thioredoxin domain
E3G57_RS05820	COG3631	Ketosteroid isomerase-related protein
E3G57_RS05835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E3G57_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS05845	COG2124	cytochrome p450
E3G57_RS05865	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS05905	COG2272	Belongs to the type-B carboxylesterase lipase family
E3G57_RS05915	COG1174	glycine betaine transport
E3G57_RS05925	COG1174	glycine betaine transport
E3G57_RS05970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E3G57_RS05980	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
E3G57_RS05985	COG0726	polysaccharide deacetylase
E3G57_RS06055	COG1722	exodeoxyribonuclease VII activity
E3G57_RS06060	COG1570	exodeoxyribonuclease VII activity
E3G57_RS06070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
E3G57_RS06085	COG1966	Carbon starvation protein
E3G57_RS06110	COG3189	MarR family transcriptional regulator
E3G57_RS06115	COG0012	GTP binding
E3G57_RS06130	COG2132	Multicopper oxidase
E3G57_RS06140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3G57_RS06150	COG0488	(ABC) transporter
E3G57_RS06205	COG2409	Drug exporters of the RND superfamily
E3G57_RS06240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E3G57_RS06260	COG1716	ATPase activity
E3G57_RS06290	COG1051	belongs to the nudix hydrolase family
E3G57_RS06315	COG1217	gtp-binding protein TYPA
E3G57_RS06325	COG2015	COG2015, Alkyl sulfatase and related hydrolases
E3G57_RS06390	COG1902	pentaerythritol trinitrate reductase activity
E3G57_RS06390	COG0446	pyridine nucleotide-disulphide oxidoreductase
E3G57_RS06400	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
E3G57_RS06410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
E3G57_RS06415	COG1012	belongs to the aldehyde dehydrogenase family
E3G57_RS06420	COG0506	proline dehydrogenase activity
E3G57_RS06425	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS06450	COG2207	Transcriptional regulator
E3G57_RS06465	COG1611	Belongs to the LOG family
E3G57_RS06470	COG1611	Belongs to the LOG family
E3G57_RS06475	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS06485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E3G57_RS06490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E3G57_RS06495	COG0463	Glycosyl transferase, family 2
E3G57_RS06510	COG0519	Catalyzes the synthesis of GMP from XMP
E3G57_RS06520	COG0297	glycogen (starch) synthase activity
E3G57_RS06535	COG3559	Exporter of polyketide antibiotics
E3G57_RS06540	COG1131	(ABC) transporter
E3G57_RS06545	COG1309	transcriptional regulator
E3G57_RS06555	COG1595	DNA-templated transcription, initiation
E3G57_RS06560	COG5662	AntiSigma factor
E3G57_RS06565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3G57_RS06635	COG0598	Magnesium transport protein CorA
E3G57_RS06640	COG2095	MarC family integral membrane protein
E3G57_RS06655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3G57_RS06660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3G57_RS06680	COG3835	regulator
E3G57_RS06685	COG1073	alpha beta
E3G57_RS06690	COG0567	Dehydrogenase, E1 component
E3G57_RS06690	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3G57_RS06700	COG2814	Major facilitator Superfamily
E3G57_RS06760	COG0277	FAD linked oxidase domain protein
E3G57_RS06765	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS06815	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3G57_RS06875	COG2814	Major facilitator Superfamily
E3G57_RS06905	COG0019	diaminopimelate decarboxylase activity
E3G57_RS06910	COG0460	homoserine dehydrogenase
E3G57_RS06915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3G57_RS06955	COG2890	protein-(glutamine-N5) methyltransferase activity
E3G57_RS06965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3G57_RS06975	COG0356	it plays a direct role in the translocation of protons across the membrane
E3G57_RS06980	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E3G57_RS07005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
E3G57_RS07065	COG0346	lactoylglutathione lyase activity
E3G57_RS07070	COG0183	Belongs to the thiolase family
E3G57_RS07075	COG2409	Drug exporters of the RND superfamily
E3G57_RS07090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E3G57_RS07095	COG0366	Alpha amylase catalytic
E3G57_RS07100	COG0058	SHG alpha-glucan phosphorylase activity
E3G57_RS07115	COG1335	isochorismatase
E3G57_RS07125	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E3G57_RS07140	COG3191	aminopeptidase activity
E3G57_RS07185	COG0604	alcohol dehydrogenase
E3G57_RS07205	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS07220	COG0419	ATPase involved in DNA repair
E3G57_RS07225	COG1024	Enoyl-CoA hydratase
E3G57_RS07235	COG0243	molybdopterin cofactor binding
E3G57_RS07250	COG2188	Transcriptional regulator
E3G57_RS07260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3G57_RS07305	COG0596	Alpha beta hydrolase
E3G57_RS07310	COG3757	hydrolase, family 25
E3G57_RS07325	COG1051	belongs to the nudix hydrolase family
E3G57_RS07345	COG1309	transcriptional regulator
E3G57_RS07360	COG4585	Histidine kinase
E3G57_RS07365	COG2197	response regulator
E3G57_RS07375	COG2239	Acts as a magnesium transporter
E3G57_RS07385	COG0300	oxidoreductase activity
E3G57_RS07395	COG0656	L-ascorbic acid biosynthetic process
E3G57_RS07410	COG1376	ErfK ybiS ycfS ynhG family protein
E3G57_RS07425	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
E3G57_RS07430	COG0433	COG0433 Predicted ATPase
E3G57_RS07445	COG0300	oxidoreductase activity
E3G57_RS07460	COG1301	dicarboxylic acid transport
E3G57_RS07470	COG0531	amino acid
E3G57_RS07490	COG4424	Sulfotransferase
E3G57_RS07495	COG3119	arylsulfatase activity
E3G57_RS07535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3G57_RS07535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3G57_RS07540	COG0662	Cupin 2, conserved barrel domain protein
E3G57_RS07570	COG2902	Dehydrogenase
E3G57_RS07575	COG0824	Thioesterase
E3G57_RS07590	COG0366	Alpha amylase catalytic
E3G57_RS07625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
E3G57_RS07645	COG1309	transcriptional regulator
E3G57_RS07660	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
E3G57_RS07755	COG0740	serine-type endopeptidase activity
E3G57_RS07760	COG0740	serine-type endopeptidase activity
E3G57_RS07810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
E3G57_RS07820	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3G57_RS07820	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3G57_RS07825	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3G57_RS07835	COG1388	LysM domain
E3G57_RS07865	COG0525	valine-tRNA ligase activity
E3G57_RS07870	COG0285	dihydrofolate synthase activity
E3G57_RS07885	COG1530	ribonuclease E activity
E3G57_RS07885	COG1530	ribonuclease E activity
E3G57_RS07905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
E3G57_RS07925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3G57_RS07930	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
E3G57_RS07935	COG0542	response to heat
E3G57_RS07945	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
E3G57_RS07955	COG0406	alpha-ribazole phosphatase activity
E3G57_RS07960	COG2755	lipolytic protein G-D-S-L family
E3G57_RS07980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3G57_RS08015	COG2308	Evidence 4 Homologs of previously reported genes of
E3G57_RS08025	COG1305	Transglutaminase-like
E3G57_RS08055	COG3387	PFAM Glycoside hydrolase 15-related
E3G57_RS08070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3G57_RS08105	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
E3G57_RS08110	COG4208	sulfate ABC transporter
E3G57_RS08165	COG0484	heat shock protein binding
E3G57_RS08215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E3G57_RS08260	COG0076	glutamate decarboxylase activity
E3G57_RS08295	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS08300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3G57_RS08345	COG0423	glycine-tRNA ligase activity
E3G57_RS08350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3G57_RS08355	COG2515	1-aminocyclopropane-1-carboxylate deaminase
E3G57_RS08375	COG0358	DNA primase activity
E3G57_RS08455	COG0745	RESPONSE REGULATOR receiver
E3G57_RS08460	COG5002	protein histidine kinase activity
E3G57_RS08480	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E3G57_RS08550	COG0488	(ABC) transporter
E3G57_RS08575	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS08580	COG1335	isochorismatase
E3G57_RS08590	COG0058	SHG alpha-glucan phosphorylase activity
E3G57_RS08635	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS08640	COG0183	Belongs to the thiolase family
E3G57_RS08660	COG1228	amidohydrolase
E3G57_RS08690	COG3321	synthase
E3G57_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS08690	COG0604	alcohol dehydrogenase
E3G57_RS08710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E3G57_RS08740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E3G57_RS08770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E3G57_RS08815	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3G57_RS08820	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
E3G57_RS08880	COG0714	Associated with various cellular activities
E3G57_RS08905	COG0557	exoribonuclease II activity
E3G57_RS08915	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS08940	COG0174	glutamine synthetase
E3G57_RS08945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
E3G57_RS08975	COG2205	protein histidine kinase activity
E3G57_RS09005	COG0174	glutamine synthetase
E3G57_RS09015	COG0477	Major facilitator Superfamily
E3G57_RS09025	COG3486	L-lysine 6-monooxygenase (NADPH) activity
E3G57_RS09045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
E3G57_RS09050	COG0321	lipoyl(octanoyl) transferase activity
E3G57_RS09070	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3G57_RS09075	COG1872	DUF167
E3G57_RS09095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E3G57_RS09105	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
E3G57_RS09110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
E3G57_RS09140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3G57_RS09185	COG2010	Cytochrome c
E3G57_RS09190	COG1845	cytochrome c oxidase, subunit III
E3G57_RS09195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3G57_RS09230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E3G57_RS09255	COG0003	Pfam Anion-transporting ATPase
E3G57_RS09265	COG0204	Acyl-transferase
E3G57_RS09270	COG5650	phosphatidylinositol metabolic process
E3G57_RS09280	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
E3G57_RS09305	COG0142	geranyltranstransferase activity
E3G57_RS09345	COG0768	penicillin binding
E3G57_RS09365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E3G57_RS09375	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
E3G57_RS09390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3G57_RS09415	COG0640	Transcriptional regulator
E3G57_RS09470	COG0154	amidase activity
E3G57_RS09480	COG2957	Belongs to the agmatine deiminase family
E3G57_RS09490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3G57_RS09500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3G57_RS09510	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS09540	COG2814	Major facilitator Superfamily
E3G57_RS09560	COG4584	PFAM Integrase catalytic
E3G57_RS09640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS09645	COG2030	dehydratase
E3G57_RS09665	COG1024	Enoyl-CoA hydratase
E3G57_RS09680	COG1309	transcriptional regulator
E3G57_RS09700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E3G57_RS09745	COG2072	flavoprotein involved in K transport
E3G57_RS09760	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS09765	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS09785	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS09830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E3G57_RS09860	COG1968	undecaprenyl-diphosphatase activity
E3G57_RS09895	COG1218	3'(2'),5'-bisphosphate nucleotidase
E3G57_RS09905	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS09930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E3G57_RS09940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E3G57_RS09940	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
E3G57_RS09955	COG2860	membrane
E3G57_RS09965	COG1410	methionine synthase
E3G57_RS09965	COG0646	methionine synthase
E3G57_RS09970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3G57_RS09980	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
E3G57_RS10015	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E3G57_RS10020	COG1034	ATP synthesis coupled electron transport
E3G57_RS10025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
E3G57_RS10030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3G57_RS10110	COG0513	Belongs to the DEAD box helicase family
E3G57_RS10145	COG0028	Belongs to the TPP enzyme family
E3G57_RS10160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3G57_RS10165	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
E3G57_RS10170	COG4122	O-methyltransferase activity
E3G57_RS10200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3G57_RS10205	COG4521	taurine ABC transporter
E3G57_RS10210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E3G57_RS10245	COG2378	regulation of single-species biofilm formation
E3G57_RS10250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3G57_RS10285	COG0300	oxidoreductase activity
E3G57_RS10340	COG1574	metal-dependent hydrolase with the TIM-barrel fold
E3G57_RS10350	COG0463	Glycosyl transferase, family 2
E3G57_RS10355	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS10380	COG3321	synthase
E3G57_RS10380	COG0604	alcohol dehydrogenase
E3G57_RS10400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3G57_RS10410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E3G57_RS10415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS10435	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
E3G57_RS10460	COG4842	Belongs to the WXG100 family
E3G57_RS10490	COG0464	growth
E3G57_RS10545	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E3G57_RS10550	COG1169	isochorismate synthase
E3G57_RS10555	COG0789	Transcriptional regulator
E3G57_RS10560	COG1021	2,3-dihydroxybenzoate-AMP ligase
E3G57_RS10590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
E3G57_RS10595	COG1132	(ABC) transporter
E3G57_RS10600	COG1132	(ABC) transporter
E3G57_RS10600	COG2375	cellular response to nickel ion
E3G57_RS10605	COG0477	Major facilitator Superfamily
E3G57_RS10610	COG5285	phytanoyl-CoA dioxygenase
E3G57_RS10620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3G57_RS10625	COG0456	acetyltransferase
E3G57_RS10640	COG2837	iron assimilation
E3G57_RS10650	COG2186	Transcriptional regulator
E3G57_RS10655	COG2807	transmembrane transport
E3G57_RS10665	COG2409	Drug exporters of the RND superfamily
E3G57_RS10670	COG3629	intracellular signal transduction
E3G57_RS10675	COG1012	belongs to the aldehyde dehydrogenase family
E3G57_RS10715	COG0475	glutathione-regulated potassium exporter activity
E3G57_RS10780	COG0237	dephospho-CoA kinase activity
E3G57_RS10780	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
E3G57_RS10955	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
E3G57_RS10960	COG0072	phenylalanine-tRNA ligase activity
E3G57_RS10960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3G57_RS10970	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
E3G57_RS10975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E3G57_RS10980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E3G57_RS10985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E3G57_RS10990	COG1438	arginine binding
E3G57_RS10995	COG0137	argininosuccinate synthase activity
E3G57_RS11035	COG2835	tetraacyldisaccharide 4'-kinase activity
E3G57_RS11040	COG1309	transcriptional regulator
E3G57_RS11045	COG2094	Belongs to the DNA glycosylase MPG family
E3G57_RS11060	COG0488	(ABC) transporter
E3G57_RS11070	COG0647	UMP catabolic process
E3G57_RS11085	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
E3G57_RS11105	COG0504	CTP synthase activity
E3G57_RS11110	COG0494	nUDIX hydrolase
E3G57_RS11125	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
E3G57_RS11130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
E3G57_RS11145	COG1160	GTP binding
E3G57_RS11195	COG1053	succinate dehydrogenase
E3G57_RS11195	COG3976	FMN-binding domain protein
E3G57_RS11225	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS11280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E3G57_RS11280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E3G57_RS11295	COG1253	flavin adenine dinucleotide binding
E3G57_RS11300	COG1253	flavin adenine dinucleotide binding
E3G57_RS11310	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
E3G57_RS11365	COG0832	Belongs to the urease beta subunit family
E3G57_RS11375	COG0830	nickel cation binding
E3G57_RS11390	COG1252	NADH dehydrogenase
E3G57_RS11400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS11435	COG0243	molybdopterin cofactor binding
E3G57_RS11440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E3G57_RS11445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E3G57_RS11460	COG1546	Belongs to the CinA family
E3G57_RS11460	COG1058	Belongs to the CinA family
E3G57_RS11470	COG4977	sequence-specific DNA binding
E3G57_RS11475	COG1741	Belongs to the pirin family
E3G57_RS11495	COG1968	undecaprenyl-diphosphatase activity
E3G57_RS11500	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
E3G57_RS11525	COG0277	FAD linked oxidase domain protein
E3G57_RS11535	COG1309	transcriptional regulator
E3G57_RS11550	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
E3G57_RS11555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E3G57_RS11585	COG4290	ribonuclease
E3G57_RS11615	COG3883	PFAM NLP P60 protein
E3G57_RS11615	COG0791	NLP P60 protein
E3G57_RS11650	COG0477	Major facilitator Superfamily
E3G57_RS11670	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3G57_RS11675	COG0070	glutamate synthase
E3G57_RS11675	COG0069	glutamate synthase activity
E3G57_RS11675	COG0067	glutamate synthase
E3G57_RS11700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3G57_RS11715	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS11730	COG0443	Heat shock 70 kDa protein
E3G57_RS11735	COG0596	Alpha beta hydrolase
E3G57_RS11755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E3G57_RS11765	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
E3G57_RS11790	COG2890	protein-(glutamine-N5) methyltransferase activity
E3G57_RS11855	COG1982	Orn Lys Arg decarboxylase major
E3G57_RS11920	COG2957	Belongs to the agmatine deiminase family
E3G57_RS11995	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
E3G57_RS12020	COG0288	reversible hydration of carbon dioxide
E3G57_RS12090	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
E3G57_RS12140	COG0640	Transcriptional regulator
E3G57_RS12150	COG0798	PFAM Bile acid sodium symporter
E3G57_RS12155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E3G57_RS12165	COG0179	Fumarylacetoacetate (FAA) hydrolase
E3G57_RS12235	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E3G57_RS12240	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
E3G57_RS12265	COG1917	Cupin 2, conserved barrel domain protein
E3G57_RS12270	COG3707	response regulator
E3G57_RS12330	COG0640	Transcriptional regulator
E3G57_RS12350	COG1309	transcriptional regulator
E3G57_RS12355	COG2072	flavoprotein involved in K transport
E3G57_RS12365	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS12370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E3G57_RS12375	COG0561	phosphatase activity
E3G57_RS12380	COG0673	inositol 2-dehydrogenase activity
E3G57_RS12385	COG0738	Major facilitator superfamily
E3G57_RS12470	COG1271	oxidase subunit
E3G57_RS12475	COG1294	oxidase, subunit
E3G57_RS12480	COG4988	ABC transporter
E3G57_RS12485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3G57_RS12510	COG1946	Acyl-CoA thioesterase
E3G57_RS12520	COG2076	Multidrug Resistance protein
E3G57_RS12555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3G57_RS12560	COG1846	Transcriptional regulator
E3G57_RS12595	COG0483	inositol monophosphate 1-phosphatase activity
E3G57_RS12605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
E3G57_RS12610	COG0131	Imidazoleglycerol-phosphate dehydratase
E3G57_RS12615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3G57_RS12640	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
E3G57_RS12655	COG1309	transcriptional regulator
E3G57_RS12670	COG0583	DNA-binding transcription factor activity
E3G57_RS12675	COG0579	oxidoreductase
E3G57_RS12715	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
E3G57_RS12715	COG2755	lipolytic protein G-D-S-L family
E3G57_RS12760	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
E3G57_RS12780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
E3G57_RS12785	COG2814	Major facilitator Superfamily
E3G57_RS12790	COG0583	DNA-binding transcription factor activity
E3G57_RS12840	COG2239	Acts as a magnesium transporter
E3G57_RS12870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E3G57_RS12880	COG2304	oxidoreductase activity
E3G57_RS12890	COG0714	Associated with various cellular activities
E3G57_RS12900	COG3883	PFAM NLP P60 protein
E3G57_RS12900	COG0791	NLP P60 protein
E3G57_RS12910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E3G57_RS12915	COG1309	transcriptional regulator
E3G57_RS12940	COG0488	(ABC) transporter
E3G57_RS12955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3G57_RS12970	COG0456	acetyltransferase
E3G57_RS12980	COG2151	metal-sulfur cluster biosynthetic enzyme
E3G57_RS12995	COG0396	ATPase activity
E3G57_RS13020	COG1131	(ABC) transporter
E3G57_RS13040	COG1309	transcriptional regulator
E3G57_RS13065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3G57_RS13130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3G57_RS13190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E3G57_RS13250	COG0531	amino acid
E3G57_RS13305	COG2011	ABC-type metal ion transport system permease component
E3G57_RS13310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E3G57_RS13315	COG1464	Belongs to the NlpA lipoprotein family
E3G57_RS13330	COG0477	Major facilitator Superfamily
E3G57_RS13365	COG0657	acetylesterase activity
E3G57_RS13370	COG1953	Uracil, thiamine, allantoin
E3G57_RS13380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
E3G57_RS13385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3G57_RS13395	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
E3G57_RS13405	COG1758	RNA polymerase activity
E3G57_RS13425	COG0284	orotidine-5'-phosphate decarboxylase activity
E3G57_RS13430	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E3G57_RS13435	COG0505	Belongs to the CarA family
E3G57_RS13455	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
E3G57_RS13475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3G57_RS13485	COG0006	proline dipeptidase activity
E3G57_RS13500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
E3G57_RS13505	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
E3G57_RS13520	COG4106	trans-aconitate 2-methyltransferase activity
E3G57_RS13535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E3G57_RS13550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E3G57_RS13600	COG0701	Predicted permease
E3G57_RS13625	COG2272	Belongs to the type-B carboxylesterase lipase family
E3G57_RS13665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E3G57_RS13675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3G57_RS13685	COG0747	negative chemotaxis
E3G57_RS13690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3G57_RS13705	COG2255	four-way junction helicase activity
E3G57_RS13715	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
E3G57_RS13750	COG1946	Acyl-CoA thioesterase
E3G57_RS13755	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
E3G57_RS13765	COG0438	transferase activity, transferring glycosyl groups
E3G57_RS13805	COG4762	Protein conserved in bacteria
E3G57_RS13840	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3G57_RS13860	COG4585	Histidine kinase
E3G57_RS13915	COG3831	ATPase activity
E3G57_RS13920	COG0714	Associated with various cellular activities
E3G57_RS13925	COG2425	protein containing a von Willebrand factor type A (vWA) domain
E3G57_RS13930	COG3552	Protein containing von Willebrand factor type A (VWA) domain
E3G57_RS13935	COG4715	Zinc finger, swim domain protein
E3G57_RS14095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3G57_RS14110	COG2080	2 iron, 2 sulfur cluster binding
E3G57_RS14110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E3G57_RS14125	COG0402	S-adenosylhomocysteine deaminase activity
E3G57_RS14145	COG2233	PERMEase
E3G57_RS14165	COG1953	Uracil, thiamine, allantoin
E3G57_RS14175	COG1301	dicarboxylic acid transport
E3G57_RS14185	COG4266	Belongs to the allantoicase family
E3G57_RS14195	COG0596	Alpha beta hydrolase
E3G57_RS14210	COG0501	Belongs to the peptidase M48B family
E3G57_RS14225	COG0477	Major facilitator Superfamily
E3G57_RS14240	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
E3G57_RS14280	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E3G57_RS14290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3G57_RS14330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3G57_RS14355	COG3253	May function as heme-dependent peroxidase
E3G57_RS14360	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
E3G57_RS14365	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
E3G57_RS14375	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E3G57_RS14395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E3G57_RS14400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E3G57_RS14405	COG0531	amino acid
E3G57_RS14410	COG0569	domain protein
E3G57_RS14440	COG0702	epimerase
E3G57_RS14455	COG0756	dUTP diphosphatase activity
E3G57_RS14500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3G57_RS14550	COG3220	belongs to the UPF0276 family
E3G57_RS14625	COG1388	LysM domain
E3G57_RS14640	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS14650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E3G57_RS14670	COG1196	nuclear chromosome segregation
E3G57_RS14690	COG1126	abc transporter atp-binding protein
E3G57_RS14695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3G57_RS14700	COG0765	amino acid transport
E3G57_RS14705	COG0765	amino acid transport
E3G57_RS14755	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
E3G57_RS14760	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
E3G57_RS14775	COG1842	Phage shock protein A
E3G57_RS14780	COG1396	sequence-specific DNA binding
E3G57_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS14800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
E3G57_RS14855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
E3G57_RS14860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E3G57_RS14875	COG3214	Protein conserved in bacteria
E3G57_RS14925	COG0659	secondary active sulfate transmembrane transporter activity
E3G57_RS14935	COG0686	Belongs to the AlaDH PNT family
E3G57_RS15020	COG2977	Belongs to the P-Pant transferase superfamily
E3G57_RS15025	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E3G57_RS15045	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS15050	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS15055	COG1024	Enoyl-CoA hydratase
E3G57_RS15080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E3G57_RS15105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3G57_RS15105	COG1017	nitric oxide dioxygenase activity
E3G57_RS15110	COG1959	2 iron, 2 sulfur cluster binding
E3G57_RS15155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
E3G57_RS15155	COG1648	precorrin-2 dehydrogenase activity
E3G57_RS15180	COG0604	alcohol dehydrogenase
E3G57_RS15180	COG3321	synthase
E3G57_RS15180	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS15240	COG0579	oxidoreductase
E3G57_RS15260	COG1492	cobalamin metabolic process
E3G57_RS15270	COG1376	ErfK ybiS ycfS ynhG family protein
E3G57_RS15295	COG0750	zinc metalloprotease
E3G57_RS15320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
E3G57_RS15360	COG0412	Dienelactone hydrolase
E3G57_RS15385	COG0528	UMP kinase activity
E3G57_RS15390	COG3973	AAA domain
E3G57_RS15405	COG2723	6-phospho-beta-galactosidase activity
E3G57_RS15440	COG1309	transcriptional regulator
E3G57_RS15480	COG0583	DNA-binding transcription factor activity
E3G57_RS15505	COG0792	nuclease activity
E3G57_RS15585	COG0336	Belongs to the RNA methyltransferase TrmD family
E3G57_RS15625	COG1686	Belongs to the peptidase S11 family
E3G57_RS15645	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
E3G57_RS15665	COG1304	FMN binding
E3G57_RS15690	COG1254	Belongs to the acylphosphatase family
E3G57_RS15715	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
E3G57_RS15720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
E3G57_RS15740	COG0571	ribonuclease III activity
E3G57_RS15750	COG3599	regulation of cell shape
E3G57_RS15795	COG0742	ribosomal rna small subunit methyltransferase
E3G57_RS15800	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E3G57_RS15815	COG0657	acetylesterase activity
E3G57_RS15820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS15840	COG2124	cytochrome p450
E3G57_RS15855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E3G57_RS15860	COG1461	Dihydroxyacetone kinase
E3G57_RS15870	COG1024	Enoyl-CoA hydratase
E3G57_RS15895	COG1181	Belongs to the D-alanine--D-alanine ligase family
E3G57_RS15900	COG0626	cystathionine gamma-synthase activity
E3G57_RS15905	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
E3G57_RS15985	COG0179	Fumarylacetoacetate (FAA) hydrolase
E3G57_RS16000	COG2271	Major facilitator Superfamily
E3G57_RS16035	COG0583	DNA-binding transcription factor activity
E3G57_RS16045	COG0778	Nitroreductase
E3G57_RS16060	COG1309	transcriptional regulator
E3G57_RS16065	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E3G57_RS16070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E3G57_RS16075	COG2124	cytochrome p450
E3G57_RS16150	COG0440	acetolactate synthase activity
E3G57_RS16165	COG1748	Saccharopine dehydrogenase
E3G57_RS16170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3G57_RS16190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3G57_RS16210	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
E3G57_RS16220	COG2272	Belongs to the type-B carboxylesterase lipase family
E3G57_RS16235	COG0745	RESPONSE REGULATOR receiver
E3G57_RS16240	COG2205	protein histidine kinase activity
E3G57_RS16265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
E3G57_RS16295	COG1024	Enoyl-CoA hydratase
E3G57_RS16300	COG0778	Nitroreductase
E3G57_RS16310	COG2252	PERMEase
E3G57_RS16350	COG2197	response regulator
E3G57_RS16355	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E3G57_RS16365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E3G57_RS16390	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E3G57_RS16405	COG1309	transcriptional regulator
E3G57_RS16435	COG0110	maltose O-acetyltransferase activity
E3G57_RS16440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3G57_RS16465	COG1119	ATPase activity
E3G57_RS16475	COG2364	Membrane
E3G57_RS16480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3G57_RS16495	COG4607	ABC-type enterochelin transport system periplasmic component
E3G57_RS16545	COG1064	alcohol dehydrogenase
E3G57_RS16565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3G57_RS16570	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS16620	COG4584	PFAM Integrase catalytic
E3G57_RS16655	COG0477	Major facilitator Superfamily
E3G57_RS16675	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS16705	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS16730	COG1335	isochorismatase
E3G57_RS16740	COG2855	membrane
E3G57_RS16750	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS16765	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS16775	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS16780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E3G57_RS16840	COG2272	Belongs to the type-B carboxylesterase lipase family
E3G57_RS16845	COG2272	Belongs to the type-B carboxylesterase lipase family
E3G57_RS16855	COG0183	Belongs to the thiolase family
E3G57_RS16890	COG1309	transcriptional regulator
E3G57_RS16920	COG0789	Transcriptional regulator
E3G57_RS16930	COG0028	Belongs to the TPP enzyme family
E3G57_RS16955	COG2177	Part of the ABC transporter FtsEX involved in
E3G57_RS16960	COG2884	Cell division ATP-binding protein ftsE
E3G57_RS16970	COG0668	transmembrane transport
E3G57_RS17010	COG0483	inositol monophosphate 1-phosphatase activity
E3G57_RS17015	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS17020	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS17035	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS17045	COG0542	response to heat
E3G57_RS17090	COG3480	Lon protease (S16) C-terminal proteolytic domain
E3G57_RS17095	COG3011	Protein conserved in bacteria
E3G57_RS17185	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E3G57_RS17190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E3G57_RS17195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E3G57_RS17230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E3G57_RS17230	COG0475	glutathione-regulated potassium exporter activity
E3G57_RS17245	COG0596	Alpha beta hydrolase
E3G57_RS17260	COG0745	RESPONSE REGULATOR receiver
E3G57_RS17270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3G57_RS17270	COG2146	nitrite reductase [NAD(P)H] activity
E3G57_RS17275	COG2223	nitrite transmembrane transporter activity
E3G57_RS17315	COG0513	Belongs to the DEAD box helicase family
E3G57_RS17330	COG0406	alpha-ribazole phosphatase activity
E3G57_RS17340	COG0456	acetyltransferase
E3G57_RS17350	COG1597	lipid kinase activity
E3G57_RS17365	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E3G57_RS17375	COG1595	DNA-templated transcription, initiation
E3G57_RS17385	COG2135	peptidase activity
E3G57_RS17390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
E3G57_RS17395	COG1162	GTPase activity
E3G57_RS17430	COG1309	transcriptional regulator
E3G57_RS17435	COG0653	protein targeting
E3G57_RS17445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3G57_RS17450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E3G57_RS17460	COG1309	transcriptional regulator
E3G57_RS17475	COG5401	PFAM Sporulation and spore germination
E3G57_RS17480	COG5002	protein histidine kinase activity
E3G57_RS17490	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS17495	COG1285	pathogenesis
E3G57_RS17535	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3G57_RS17540	COG0531	amino acid
E3G57_RS17550	COG1482	cell wall glycoprotein biosynthetic process
E3G57_RS17580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3G57_RS17585	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
E3G57_RS17585	COG0778	Nitroreductase
E3G57_RS17600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
E3G57_RS17615	COG1316	TRANSCRIPTIONal
E3G57_RS17635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3G57_RS17645	COG2175	clavaminate synthase activity
E3G57_RS17670	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
E3G57_RS17670	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
E3G57_RS17680	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS17695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E3G57_RS17705	COG0424	maF-like protein
E3G57_RS17720	COG2226	methyltransferase
E3G57_RS17730	COG3265	gluconokinase activity
E3G57_RS17750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS17840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3G57_RS17855	COG1917	Cupin 2, conserved barrel domain protein
E3G57_RS17860	COG2249	NAD(P)H dehydrogenase (quinone) activity
E3G57_RS17865	COG5285	phytanoyl-CoA dioxygenase
E3G57_RS17870	COG3214	Protein conserved in bacteria
E3G57_RS17880	COG1280	lysine exporter protein (LysE YggA)
E3G57_RS17945	COG1733	regulation of RNA biosynthetic process
E3G57_RS17970	COG4770	biotin carboxylase activity
E3G57_RS18005	COG1012	belongs to the aldehyde dehydrogenase family
E3G57_RS18010	COG1309	transcriptional regulator
E3G57_RS18015	COG1201	RNA secondary structure unwinding
E3G57_RS18030	COG0564	pseudouridine synthase activity
E3G57_RS18050	COG1473	amidohydrolase
E3G57_RS18050	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
E3G57_RS18065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E3G57_RS18080	COG3883	PFAM NLP P60 protein
E3G57_RS18080	COG0791	NLP P60 protein
E3G57_RS18125	COG2009	succinate dehydrogenase
E3G57_RS18140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3G57_RS18145	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3G57_RS18150	COG1595	DNA-templated transcription, initiation
E3G57_RS18160	COG1686	Belongs to the peptidase S11 family
E3G57_RS18175	COG0708	Exodeoxyribonuclease III
E3G57_RS18235	COG1733	regulation of RNA biosynthetic process
E3G57_RS18240	COG2910	NAD(P)H-binding
E3G57_RS18245	COG1716	ATPase activity
E3G57_RS18245	COG0842	Transport permease protein
E3G57_RS18245	COG1131	(ABC) transporter
E3G57_RS18250	COG1357	PFAM Pentapeptide repeats (8 copies)
E3G57_RS18255	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E3G57_RS18265	COG1073	alpha beta
E3G57_RS18270	COG1309	transcriptional regulator
E3G57_RS18335	COG0519	Catalyzes the synthesis of GMP from XMP
E3G57_RS18335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
E3G57_RS18345	COG0516	GMP reductase activity
E3G57_RS18390	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
E3G57_RS18405	COG0456	acetyltransferase
E3G57_RS18425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E3G57_RS18430	COG0076	glutamate decarboxylase activity
E3G57_RS18440	COG2267	carboxylic ester hydrolase activity
E3G57_RS18445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E3G57_RS18470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS18480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E3G57_RS18485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
E3G57_RS18520	COG1404	Belongs to the peptidase S8 family
E3G57_RS18550	COG2267	carboxylic ester hydrolase activity
E3G57_RS18605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
E3G57_RS18610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3G57_RS18620	COG2268	Band 7 protein
E3G57_RS18630	COG1088	dTDP-glucose 4,6-dehydratase activity
E3G57_RS18635	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
E3G57_RS18680	COG0616	signal peptide processing
E3G57_RS18695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS18715	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
E3G57_RS18725	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
E3G57_RS18735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E3G57_RS18750	COG2272	Belongs to the type-B carboxylesterase lipase family
E3G57_RS18775	COG0477	Major facilitator Superfamily
E3G57_RS18790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
E3G57_RS18805	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
E3G57_RS18830	COG0088	Forms part of the polypeptide exit tunnel
E3G57_RS18835	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
E3G57_RS18840	COG0051	transcription antitermination factor activity, RNA binding
E3G57_RS18845	COG0259	pyridoxamine-phosphate oxidase activity
E3G57_RS18875	COG0531	amino acid
E3G57_RS18905	COG0535	radical SAM domain protein
E3G57_RS18930	COG1834	amidinotransferase
E3G57_RS18935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E3G57_RS18940	COG0531	amino acid
E3G57_RS18985	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
E3G57_RS18990	COG1309	transcriptional regulator
E3G57_RS19015	COG1024	Enoyl-CoA hydratase
E3G57_RS19030	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS19060	COG1113	amino acid transport
E3G57_RS19075	COG0085	RNA polymerase activity
E3G57_RS19080	COG0243	molybdopterin cofactor binding
E3G57_RS19135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E3G57_RS19150	COG0277	FAD linked oxidase domain protein
E3G57_RS19170	COG4941	Belongs to the sigma-70 factor family
E3G57_RS19205	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3G57_RS19245	COG0783	Belongs to the Dps family
E3G57_RS19250	COG0693	protein deglycase activity
E3G57_RS19295	COG1404	Belongs to the peptidase S8 family
E3G57_RS19315	COG1280	lysine exporter protein (LysE YggA)
E3G57_RS19385	COG0501	Belongs to the peptidase M48B family
E3G57_RS19390	COG0142	geranyltranstransferase activity
E3G57_RS19395	COG0644	oxidoreductase
E3G57_RS19405	COG0438	transferase activity, transferring glycosyl groups
E3G57_RS19425	COG4948	Mandelate Racemase Muconate Lactonizing
E3G57_RS19445	COG3706	GGDEF domain
E3G57_RS19460	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3G57_RS19470	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
E3G57_RS19475	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS19480	COG4221	oxidoreductase activity
E3G57_RS19530	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E3G57_RS19535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E3G57_RS19570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E3G57_RS19615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3G57_RS19625	COG0785	Cytochrome C biogenesis protein
E3G57_RS19630	COG0386	Belongs to the glutathione peroxidase family
E3G57_RS19635	COG0406	alpha-ribazole phosphatase activity
E3G57_RS19650	COG3590	peptidase
E3G57_RS19700	COG1648	precorrin-2 dehydrogenase activity
E3G57_RS19700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
E3G57_RS19725	COG2030	dehydratase
E3G57_RS19750	COG2070	2-Nitropropane dioxygenase
E3G57_RS19775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E3G57_RS19780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3G57_RS19865	COG2072	flavoprotein involved in K transport
E3G57_RS19880	COG1309	transcriptional regulator
E3G57_RS19890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3G57_RS19940	COG2072	flavoprotein involved in K transport
E3G57_RS19955	COG2072	flavoprotein involved in K transport
E3G57_RS19960	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS19965	COG0657	acetylesterase activity
E3G57_RS19970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E3G57_RS19980	COG0745	RESPONSE REGULATOR receiver
E3G57_RS19985	COG5002	protein histidine kinase activity
E3G57_RS19995	COG2072	flavoprotein involved in K transport
E3G57_RS20010	COG0300	oxidoreductase activity
E3G57_RS20065	COG2814	Major facilitator Superfamily
E3G57_RS20070	COG0812	UDP-N-acetylmuramate dehydrogenase activity
E3G57_RS20165	COG2733	membrane
E3G57_RS20175	COG2326	polyphosphate kinase activity
E3G57_RS20180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E3G57_RS20215	COG2224	Isocitrate lyase
E3G57_RS20255	COG2226	methyltransferase
E3G57_RS20305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E3G57_RS20340	COG0667	Aldo Keto reductase
E3G57_RS20365	COG4552	Acetyltransferase involved in intracellular survival and related
E3G57_RS20370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS20395	COG1505	serine-type exopeptidase activity
E3G57_RS20415	COG1073	alpha beta
E3G57_RS20420	COG2326	polyphosphate kinase activity
E3G57_RS20435	COG2223	nitrite transmembrane transporter activity
E3G57_RS20440	COG0640	Transcriptional regulator
E3G57_RS20470	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
E3G57_RS20490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E3G57_RS20515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3G57_RS20525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3G57_RS20530	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS20540	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS20545	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS20550	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS20560	COG2070	2-Nitropropane dioxygenase
E3G57_RS20570	COG1024	Enoyl-CoA hydratase
E3G57_RS20575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E3G57_RS20580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS20615	COG4638	Rieske (2fe-2S)
E3G57_RS20655	COG0175	sulfate reduction
E3G57_RS20725	COG2814	Major facilitator Superfamily
E3G57_RS20735	COG0351	phosphomethylpyrimidine kinase
E3G57_RS20745	COG1252	NADH dehydrogenase
E3G57_RS20755	COG1309	transcriptional regulator
E3G57_RS20765	COG1012	belongs to the aldehyde dehydrogenase family
E3G57_RS20800	COG0494	nUDIX hydrolase
E3G57_RS20810	COG2234	aminopeptidase activity
E3G57_RS20815	COG2234	aminopeptidase activity
E3G57_RS20825	COG1131	(ABC) transporter
E3G57_RS20830	COG2022	thiamine diphosphate biosynthetic process
E3G57_RS20865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3G57_RS20870	COG0515	serine threonine protein kinase
E3G57_RS20875	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E3G57_RS20905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3G57_RS20910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS20915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS20920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS20930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3G57_RS20935	COG1126	abc transporter atp-binding protein
E3G57_RS20940	COG0765	amino acid transport
E3G57_RS20975	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
E3G57_RS21000	COG0415	Belongs to the DNA photolyase family
E3G57_RS21005	COG1090	epimerase
E3G57_RS21015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E3G57_RS21030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E3G57_RS21065	COG1994	Peptidase M50
E3G57_RS21085	COG0586	Pfam SNARE associated Golgi protein
E3G57_RS21115	COG4221	oxidoreductase activity
E3G57_RS21135	COG0542	response to heat
E3G57_RS21155	COG0789	Transcriptional regulator
E3G57_RS21165	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E3G57_RS21240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3G57_RS21240	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E3G57_RS21260	COG2259	Doxx family
E3G57_RS21280	COG0247	lactate metabolic process
E3G57_RS21280	COG2181	nitrate reductase activity
E3G57_RS21290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
E3G57_RS21330	COG3345	alpha-galactosidase
E3G57_RS21335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
E3G57_RS21340	COG1305	Transglutaminase-like
E3G57_RS21355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3G57_RS21480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3G57_RS21550	COG1012	belongs to the aldehyde dehydrogenase family
E3G57_RS21615	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS21620	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS21635	COG3268	Saccharopine dehydrogenase
E3G57_RS21640	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS21645	COG3285	dna ligase
E3G57_RS21645	COG1793	dna ligase
E3G57_RS21655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3G57_RS21660	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS21700	COG1309	transcriptional regulator
E3G57_RS21705	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3G57_RS21720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3G57_RS21725	COG1984	allophanate hydrolase subunit 2
E3G57_RS21790	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
E3G57_RS21795	COG1802	Transcriptional regulator
E3G57_RS21825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3G57_RS21835	COG0473	3-isopropylmalate dehydrogenase activity
E3G57_RS21850	COG1053	succinate dehydrogenase
E3G57_RS21870	COG0640	Transcriptional regulator
E3G57_RS21920	COG2318	DinB family
E3G57_RS21925	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS21950	COG0183	Belongs to the thiolase family
E3G57_RS21955	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS21960	COG2030	dehydratase
E3G57_RS21975	COG0659	secondary active sulfate transmembrane transporter activity
E3G57_RS21980	COG1309	transcriptional regulator
E3G57_RS21985	COG0861	Integral membrane protein TerC family
E3G57_RS22010	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS22025	COG1472	Belongs to the glycosyl hydrolase 3 family
E3G57_RS22030	COG4941	Belongs to the sigma-70 factor family
E3G57_RS22080	COG3119	arylsulfatase activity
E3G57_RS22095	COG4981	capsule polysaccharide biosynthetic process
E3G57_RS22135	COG0438	transferase activity, transferring glycosyl groups
E3G57_RS22190	COG2197	response regulator
E3G57_RS22195	COG3850	Histidine kinase
E3G57_RS22215	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
E3G57_RS22235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
E3G57_RS22245	COG2409	Drug exporters of the RND superfamily
E3G57_RS22290	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3G57_RS22300	COG2197	response regulator
E3G57_RS22330	COG2353	YceI-like domain
E3G57_RS22345	COG2409	Drug exporters of the RND superfamily
E3G57_RS22360	COG4552	Acetyltransferase involved in intracellular survival and related
E3G57_RS22365	COG1832	CoA-binding protein
E3G57_RS22380	COG3590	peptidase
E3G57_RS22385	COG1376	ErfK ybiS ycfS ynhG family protein
E3G57_RS22395	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS22405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E3G57_RS22415	COG1937	Protein conserved in bacteria
E3G57_RS22445	COG4122	O-methyltransferase activity
E3G57_RS22460	COG2267	carboxylic ester hydrolase activity
E3G57_RS22490	COG1704	LemA family
E3G57_RS22500	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS22555	COG1024	Enoyl-CoA hydratase
E3G57_RS22560	COG1802	Transcriptional regulator
E3G57_RS22570	COG2267	carboxylic ester hydrolase activity
E3G57_RS22575	COG1309	transcriptional regulator
E3G57_RS22605	COG0435	Glutathione S-transferase
E3G57_RS22645	COG1024	Enoyl-CoA hydratase
E3G57_RS22655	COG2211	Major facilitator Superfamily
E3G57_RS22660	COG2365	Tyrosine phosphatase family
E3G57_RS22725	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS22730	COG1012	belongs to the aldehyde dehydrogenase family
E3G57_RS22745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3G57_RS22750	COG1960	acyl-CoA dehydrogenase activity
E3G57_RS22755	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
E3G57_RS22770	COG2226	methyltransferase
E3G57_RS22785	COG3800	Transcriptional regulator
E3G57_RS22785	COG1396	sequence-specific DNA binding
E3G57_RS22795	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
E3G57_RS22835	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS22895	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
E3G57_RS22905	COG0129	dihydroxy-acid dehydratase activity
E3G57_RS22925	COG2186	Transcriptional regulator
E3G57_RS22955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E3G57_RS22960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E3G57_RS22990	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS23030	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS23050	COG0318	PFAM AMP-dependent synthetase and ligase
E3G57_RS23055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E3G57_RS23060	COG1136	(ABC) transporter
E3G57_RS23070	COG1104	cysteine desulfurase activity
E3G57_RS23130	COG1309	transcriptional regulator
E3G57_RS23135	COG1819	glycosyl
E3G57_RS23180	COG1819	glycosyl
E3G57_RS23295	COG3263	regulation of cellular component size
E3G57_RS23375	COG1595	DNA-templated transcription, initiation
E3G57_RS23385	COG0783	Belongs to the Dps family
E3G57_RS23430	COG1252	NADH dehydrogenase
E3G57_RS23450	COG1937	Protein conserved in bacteria
E3G57_RS23545	COG2140	Oxalate decarboxylase
E3G57_RS23570	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
E3G57_RS23590	COG1376	ErfK ybiS ycfS ynhG family protein
E3G57_RS23620	COG2030	dehydratase
E3G57_RS23625	COG0488	(ABC) transporter
E3G57_RS23630	COG3757	hydrolase, family 25
E3G57_RS23690	COG0583	DNA-binding transcription factor activity
E3G57_RS23700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS23715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3G57_RS23720	COG3757	hydrolase, family 25
E3G57_RS23745	COG2205	protein histidine kinase activity
E3G57_RS23750	COG0745	RESPONSE REGULATOR receiver
E3G57_RS23790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E3G57_RS23805	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
E3G57_RS23815	COG1335	isochorismatase
E3G57_RS23835	COG0629	single-stranded DNA binding
E3G57_RS23850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3G57_RS23880	COG1260	myo-inositol-1-phosphate synthase
E3G57_RS23885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3G57_RS23890	COG1113	amino acid transport
E3G57_RS23905	COG1309	transcriptional regulator
E3G57_RS23910	COG1028	Short-chain dehydrogenase reductase Sdr
E3G57_RS23925	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3G57_RS23930	COG0022	dehydrogenase e1 component
E3G57_RS23945	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
E3G57_RS23950	COG2311	Membrane
E3G57_RS24015	COG0617	tRNA 3'-terminal CCA addition
E3G57_RS24035	COG1595	DNA-templated transcription, initiation
E3G57_RS24055	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3G57_RS24055	COG3409	Peptidoglycan-binding domain 1 protein
E3G57_RS24065	COG2124	cytochrome p450
E3G57_RS24075	COG1309	transcriptional regulator
E3G57_RS24095	COG1192	Involved in chromosome partitioning
E3G57_RS24100	COG0357	Ribosomal RNA small subunit methyltransferase G
E3G57_RS24110	COG0706	membrane insertase activity
E3G57_RS24115	COG0759	Could be involved in insertion of integral membrane proteins into the membrane