locus-tag	class	description
IN838_RS00015	COG0592	DNA-directed DNA polymerase activity
IN838_RS00020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IN838_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IN838_RS00030	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
IN838_RS00035	COG0187	DNA topoisomerase II activity
IN838_RS00120	COG2814	Major facilitator Superfamily
IN838_RS00125	COG0583	DNA-binding transcription factor activity
IN838_RS00140	COG0457	Tetratricopeptide repeat
IN838_RS00140	COG0705	Rhomboid family
IN838_RS00175	COG2815	serine threonine protein kinase
IN838_RS00175	COG0515	serine threonine protein kinase
IN838_RS00180	COG0515	serine threonine protein kinase
IN838_RS00185	COG0768	penicillin binding
IN838_RS00200	COG1716	ATPase activity
IN838_RS00205	COG1716	ATPase activity
IN838_RS00220	COG0754	glutathionylspermidine amidase activity
IN838_RS00230	COG1309	transcriptional regulator
IN838_RS00250	COG4842	Belongs to the WXG100 family
IN838_RS00270	COG0590	tRNA wobble adenosine to inosine editing
IN838_RS00280	COG0583	DNA-binding transcription factor activity
IN838_RS00285	COG1643	Atp-dependent helicase
IN838_RS00290	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS00310	COG4585	Histidine kinase
IN838_RS00330	COG1960	acyl-CoA dehydrogenase activity
IN838_RS00375	COG2072	flavoprotein involved in K transport
IN838_RS00385	COG0346	lactoylglutathione lyase activity
IN838_RS00390	COG1414	Transcriptional regulator
IN838_RS00410	COG1053	succinate dehydrogenase
IN838_RS00440	COG1785	Belongs to the alkaline phosphatase family
IN838_RS00460	COG0069	glutamate synthase activity
IN838_RS00460	COG0067	glutamate synthase
IN838_RS00460	COG0070	glutamate synthase
IN838_RS00490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IN838_RS00490	COG1796	DNA polymerase
IN838_RS00500	COG2072	flavoprotein involved in K transport
IN838_RS00510	COG2124	cytochrome p450
IN838_RS00525	COG1024	Enoyl-CoA hydratase
IN838_RS00555	COG2372	response to copper ion
IN838_RS00605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IN838_RS00625	COG5002	protein histidine kinase activity
IN838_RS00625	COG3447	MASE1 domain protein
IN838_RS00625	COG5001	Diguanylate cyclase
IN838_RS00635	COG1528	Iron-storage protein
IN838_RS00640	COG1528	Iron-storage protein
IN838_RS00645	COG1316	TRANSCRIPTIONal
IN838_RS00670	COG0406	alpha-ribazole phosphatase activity
IN838_RS00680	COG0028	Belongs to the TPP enzyme family
IN838_RS00710	COG2072	flavoprotein involved in K transport
IN838_RS00720	COG2072	flavoprotein involved in K transport
IN838_RS00740	COG1285	pathogenesis
IN838_RS00790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IN838_RS00790	COG2146	nitrite reductase [NAD(P)H] activity
IN838_RS00800	COG4133	protoheme IX ABC transporter activity
IN838_RS00805	COG2070	2-Nitropropane dioxygenase
IN838_RS00810	COG1942	4-Oxalocrotonate Tautomerase
IN838_RS00815	COG0583	DNA-binding transcription factor activity
IN838_RS00830	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS00845	COG0561	phosphatase activity
IN838_RS00865	COG1216	Glycosyl transferase, family 2
IN838_RS00870	COG0671	phosphoesterase, PA-phosphatase related
IN838_RS00875	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IN838_RS00880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IN838_RS00900	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
IN838_RS00905	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS00910	COG3321	synthase
IN838_RS00910	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IN838_RS00910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IN838_RS00915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IN838_RS00965	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS00970	COG0277	FAD linked oxidase domain protein
IN838_RS00980	COG2376	Dihydroxyacetone kinase
IN838_RS00985	COG2267	carboxylic ester hydrolase activity
IN838_RS00990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IN838_RS00995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IN838_RS01010	COG0671	phosphoesterase, PA-phosphatase related
IN838_RS01020	COG1216	Glycosyl transferase, family 2
IN838_RS01100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IN838_RS01105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IN838_RS01175	COG1960	acyl-CoA dehydrogenase activity
IN838_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS01215	COG1174	glycine betaine transport
IN838_RS01230	COG0287	Prephenate dehydrogenase
IN838_RS01240	COG0590	tRNA wobble adenosine to inosine editing
IN838_RS01280	COG0343	queuine tRNA-ribosyltransferase activity
IN838_RS01290	COG0765	amino acid transport
IN838_RS01295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IN838_RS01300	COG1793	dna ligase
IN838_RS01330	COG2271	Major facilitator Superfamily
IN838_RS01335	COG2130	NADP-dependent
IN838_RS01360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IN838_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS01435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IN838_RS01460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IN838_RS01470	COG0148	phosphopyruvate hydratase activity
IN838_RS01500	COG0860	N-Acetylmuramoyl-L-alanine amidase
IN838_RS01525	COG1492	cobalamin metabolic process
IN838_RS01550	COG1960	acyl-CoA dehydrogenase activity
IN838_RS01565	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IN838_RS01595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IN838_RS01615	COG1231	oxidoreductase activity
IN838_RS01645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IN838_RS01655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IN838_RS01685	COG2070	2-Nitropropane dioxygenase
IN838_RS01730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IN838_RS01735	COG2971	BadF BadG BcrA BcrD
IN838_RS01740	COG2814	Major facilitator Superfamily
IN838_RS01760	COG3572	ergothioneine biosynthetic process
IN838_RS01765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IN838_RS01770	COG0121	glutamine amidotransferase
IN838_RS01775	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IN838_RS01780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IN838_RS01805	COG0183	Belongs to the thiolase family
IN838_RS01810	COG2030	dehydratase
IN838_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS01820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IN838_RS01830	COG1695	Transcriptional regulator
IN838_RS01840	COG0569	domain protein
IN838_RS01840	COG0475	glutathione-regulated potassium exporter activity
IN838_RS01860	COG0714	Associated with various cellular activities
IN838_RS01905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IN838_RS01910	COG1074	ATP-dependent DNA helicase activity
IN838_RS01915	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IN838_RS01925	COG2755	lipolytic protein G-D-S-L family
IN838_RS01955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IN838_RS01960	COG1408	metallophosphoesterase
IN838_RS01965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IN838_RS01995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IN838_RS02035	COG0596	Alpha beta hydrolase
IN838_RS02035	COG2945	thiolester hydrolase activity
IN838_RS02050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IN838_RS02055	COG0747	negative chemotaxis
IN838_RS02065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IN838_RS02135	COG0582	viral genome integration into host DNA
IN838_RS02180	COG2217	Heavy metal translocating P-type atpase
IN838_RS02190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IN838_RS02250	COG2132	Multicopper oxidase
IN838_RS02285	COG0596	Alpha beta hydrolase
IN838_RS02345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN838_RS02350	COG1309	transcriptional regulator
IN838_RS02355	COG0657	acetylesterase activity
IN838_RS02360	COG1902	pentaerythritol trinitrate reductase activity
IN838_RS02365	COG1111	helicase
IN838_RS02365	COG1205	dead DEAH box helicase
IN838_RS02370	COG1278	Cold shock
IN838_RS02380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IN838_RS02380	COG1754	DNA topoisomerase type I activity
IN838_RS02390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IN838_RS02500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IN838_RS02535	COG2027	D-alanyl-D-alanine carboxypeptidase
IN838_RS02570	COG1063	alcohol dehydrogenase
IN838_RS02580	COG2267	carboxylic ester hydrolase activity
IN838_RS02590	COG1309	transcriptional regulator
IN838_RS02605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IN838_RS02650	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IN838_RS02660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IN838_RS02680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IN838_RS02685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IN838_RS02725	COG4977	sequence-specific DNA binding
IN838_RS02730	COG1194	a g-specific adenine glycosylase
IN838_RS02740	COG1316	TRANSCRIPTIONal
IN838_RS02750	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IN838_RS02760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IN838_RS02780	COG1329	Transcriptional regulator
IN838_RS02785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IN838_RS02795	COG0215	cysteine-tRNA ligase activity
IN838_RS02805	COG0584	glycerophosphoryl diester phosphodiesterase
IN838_RS02815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IN838_RS02820	COG1120	ATPase activity
IN838_RS02825	COG0803	Belongs to the bacterial solute-binding protein 9 family
IN838_RS02835	COG1309	transcriptional regulator
IN838_RS02840	COG1960	acyl-CoA dehydrogenase activity
IN838_RS02855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN838_RS02865	COG0346	lactoylglutathione lyase activity
IN838_RS02905	COG1960	acyl-CoA dehydrogenase activity
IN838_RS02910	COG1960	acyl-CoA dehydrogenase activity
IN838_RS02915	COG1960	acyl-CoA dehydrogenase activity
IN838_RS02920	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS02925	COG1960	acyl-CoA dehydrogenase activity
IN838_RS02940	COG0183	Belongs to the thiolase family
IN838_RS02970	COG1024	Enoyl-CoA hydratase
IN838_RS02975	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS03000	COG0183	Belongs to the thiolase family
IN838_RS03010	COG1960	acyl-CoA dehydrogenase activity
IN838_RS03015	COG1960	acyl-CoA dehydrogenase activity
IN838_RS03020	COG2030	dehydratase
IN838_RS03045	COG2030	dehydratase
IN838_RS03050	COG1053	succinate dehydrogenase
IN838_RS03060	COG3971	2-oxopent-4-enoate hydratase activity
IN838_RS03105	COG0651	ATP synthesis coupled electron transport
IN838_RS03115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IN838_RS03115	COG2111	Na H antiporter
IN838_RS03120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IN838_RS03140	COG0647	UMP catabolic process
IN838_RS03165	COG4221	oxidoreductase activity
IN838_RS03185	COG0459	protein refolding
IN838_RS03200	COG0714	Associated with various cellular activities
IN838_RS03250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IN838_RS03265	COG4842	Belongs to the WXG100 family
IN838_RS03310	COG0745	RESPONSE REGULATOR receiver
IN838_RS03315	COG5000	phosphorelay sensor kinase activity
IN838_RS03315	COG5002	protein histidine kinase activity
IN838_RS03320	COG0537	adenosine 5'-monophosphoramidase activity
IN838_RS03325	COG0697	spore germination
IN838_RS03335	COG0596	Alpha beta hydrolase
IN838_RS03365	COG0436	Aminotransferase
IN838_RS03375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IN838_RS03400	COG0477	Major facilitator Superfamily
IN838_RS03405	COG0386	Belongs to the glutathione peroxidase family
IN838_RS03415	COG3573	Dehydrogenase
IN838_RS03425	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IN838_RS03440	COG2837	iron assimilation
IN838_RS03445	COG1362	aminopeptidase activity
IN838_RS03525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IN838_RS03535	COG0601	transmembrane transport
IN838_RS03540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IN838_RS03545	COG4172	Belongs to the ABC transporter superfamily
IN838_RS03575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IN838_RS03585	COG0354	folic acid binding
IN838_RS03635	COG2897	thiosulfate sulfurtransferase activity
IN838_RS03655	COG0745	RESPONSE REGULATOR receiver
IN838_RS03675	COG0581	inorganic phosphate transmembrane transporter activity
IN838_RS03680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IN838_RS03685	COG0604	alcohol dehydrogenase
IN838_RS03740	COG1250	3-hydroxyacyl-CoA dehydrogenase
IN838_RS03765	COG0697	spore germination
IN838_RS03785	COG0442	prolyl-tRNA aminoacylation
IN838_RS03790	COG2814	Major facilitator Superfamily
IN838_RS04005	COG5651	PPE family
IN838_RS04010	COG0436	Aminotransferase
IN838_RS04030	COG0531	amino acid
IN838_RS04035	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IN838_RS04040	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS04050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN838_RS04055	COG2902	Dehydrogenase
IN838_RS04060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IN838_RS04065	COG1960	acyl-CoA dehydrogenase activity
IN838_RS04070	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS04075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN838_RS04085	COG0657	acetylesterase activity
IN838_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS04105	COG1902	pentaerythritol trinitrate reductase activity
IN838_RS04110	COG1902	pentaerythritol trinitrate reductase activity
IN838_RS04125	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS04140	COG1024	Enoyl-CoA hydratase
IN838_RS04185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN838_RS04190	COG0657	acetylesterase activity
IN838_RS04210	COG0183	Belongs to the thiolase family
IN838_RS04225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN838_RS04245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN838_RS04260	COG1061	Type III restriction enzyme res subunit
IN838_RS04295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IN838_RS04320	COG1278	Cold shock
IN838_RS04360	COG2814	Major facilitator Superfamily
IN838_RS04430	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IN838_RS04435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IN838_RS04465	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS04465	COG2030	dehydratase
IN838_RS04470	COG1309	transcriptional regulator
IN838_RS04480	COG1024	Enoyl-CoA hydratase
IN838_RS04485	COG1250	3-hydroxyacyl-CoA dehydrogenase
IN838_RS04495	COG3396	Phenylacetate-CoA oxygenase
IN838_RS04500	COG3460	Phenylacetate-CoA oxygenase
IN838_RS04505	COG3396	Phenylacetate-CoA oxygenase
IN838_RS04510	COG2151	metal-sulfur cluster biosynthetic enzyme
IN838_RS04515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN838_RS04540	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN838_RS04550	COG2124	cytochrome p450
IN838_RS04580	COG1764	response to oxidative stress
IN838_RS04585	COG1846	Transcriptional regulator
IN838_RS04590	COG1216	Glycosyl transferase, family 2
IN838_RS04595	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IN838_RS04625	COG0259	pyridoxamine-phosphate oxidase activity
IN838_RS04635	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS04640	COG5651	PPE family
IN838_RS04645	COG2409	Drug exporters of the RND superfamily
IN838_RS04670	COG4977	sequence-specific DNA binding
IN838_RS04695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS04705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IN838_RS04710	COG0833	amino acid
IN838_RS04725	COG2186	Transcriptional regulator
IN838_RS04730	COG0545	Peptidyl-prolyl cis-trans isomerase
IN838_RS04770	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IN838_RS04775	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IN838_RS04820	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS04835	COG3022	response to hydroperoxide
IN838_RS04845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IN838_RS04880	COG1309	transcriptional regulator
IN838_RS04915	COG1393	Belongs to the ArsC family
IN838_RS04920	COG0583	DNA-binding transcription factor activity
IN838_RS04960	COG0183	Belongs to the thiolase family
IN838_RS05005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN838_RS05045	COG0438	transferase activity, transferring glycosyl groups
IN838_RS05050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IN838_RS05065	COG2382	esterase
IN838_RS05095	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
IN838_RS05100	COG1846	Transcriptional regulator
IN838_RS05150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IN838_RS05160	COG2326	polyphosphate kinase activity
IN838_RS05175	COG2084	Dehydrogenase
IN838_RS05190	COG0523	cobalamin synthesis protein
IN838_RS05195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IN838_RS05200	COG0235	Class ii aldolase
IN838_RS05205	COG1396	sequence-specific DNA binding
IN838_RS05210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IN838_RS05215	COG0166	Belongs to the GPI family
IN838_RS05325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IN838_RS05355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IN838_RS05360	COG0315	cyclic pyranopterin monophosphate synthase activity
IN838_RS05360	COG0521	Mo-molybdopterin cofactor biosynthetic process
IN838_RS05395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IN838_RS05400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IN838_RS05435	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IN838_RS05440	COG1104	cysteine desulfurase activity
IN838_RS05590	COG2235	arginine
IN838_RS05605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IN838_RS05620	COG1252	NADH dehydrogenase
IN838_RS05630	COG0084	hydrolase, TatD family'
IN838_RS05635	COG3583	domain protein
IN838_RS05650	COG2815	serine threonine protein kinase
IN838_RS05650	COG0515	serine threonine protein kinase
IN838_RS05670	COG2409	Drug exporters of the RND superfamily
IN838_RS05675	COG1846	Transcriptional regulator
IN838_RS05675	COG0456	acetyltransferase
IN838_RS05680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IN838_RS05685	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS05700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IN838_RS05735	COG1309	transcriptional regulator
IN838_RS05780	COG3956	TIGRFAM MazG family protein
IN838_RS05795	COG2837	iron assimilation
IN838_RS05800	COG2822	iron ion transport
IN838_RS05835	COG0596	Alpha beta hydrolase
IN838_RS05860	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS05870	COG0427	acetyl-CoA hydrolase
IN838_RS05920	COG1846	Transcriptional regulator
IN838_RS05935	COG1024	Enoyl-CoA hydratase
IN838_RS05960	COG0183	Belongs to the thiolase family
IN838_RS05965	COG2755	lipolytic protein G-D-S-L family
IN838_RS05970	COG0657	acetylesterase activity
IN838_RS05980	COG1714	RDD family
IN838_RS05995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IN838_RS06015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IN838_RS06025	COG1331	Highly conserved protein containing a thioredoxin domain
IN838_RS06030	COG3631	Ketosteroid isomerase-related protein
IN838_RS06045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IN838_RS06050	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS06055	COG2124	cytochrome p450
IN838_RS06075	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS06115	COG2272	Belongs to the type-B carboxylesterase lipase family
IN838_RS06125	COG1174	glycine betaine transport
IN838_RS06135	COG1174	glycine betaine transport
IN838_RS06180	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IN838_RS06190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IN838_RS06195	COG0726	polysaccharide deacetylase
IN838_RS06265	COG1570	exodeoxyribonuclease VII activity
IN838_RS06275	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IN838_RS06290	COG1966	Carbon starvation protein
IN838_RS06315	COG3189	MarR family transcriptional regulator
IN838_RS06320	COG0012	GTP binding
IN838_RS06345	COG2132	Multicopper oxidase
IN838_RS06355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IN838_RS06365	COG0488	(ABC) transporter
IN838_RS06420	COG2409	Drug exporters of the RND superfamily
IN838_RS06455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IN838_RS06475	COG1716	ATPase activity
IN838_RS06505	COG1051	belongs to the nudix hydrolase family
IN838_RS06530	COG1217	gtp-binding protein TYPA
IN838_RS06540	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IN838_RS06545	COG2207	Transcriptional regulator
IN838_RS06545	COG1609	Transcriptional regulator
IN838_RS06605	COG1902	pentaerythritol trinitrate reductase activity
IN838_RS06605	COG0446	pyridine nucleotide-disulphide oxidoreductase
IN838_RS06615	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IN838_RS06625	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IN838_RS06630	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS06635	COG0506	proline dehydrogenase activity
IN838_RS06640	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS06665	COG2207	Transcriptional regulator
IN838_RS06680	COG1611	Belongs to the LOG family
IN838_RS06685	COG1611	Belongs to the LOG family
IN838_RS06690	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS06700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IN838_RS06710	COG0463	Glycosyl transferase, family 2
IN838_RS06725	COG0519	Catalyzes the synthesis of GMP from XMP
IN838_RS06735	COG0297	glycogen (starch) synthase activity
IN838_RS06760	COG3559	Exporter of polyketide antibiotics
IN838_RS06765	COG1131	(ABC) transporter
IN838_RS06770	COG1309	transcriptional regulator
IN838_RS06780	COG1595	DNA-templated transcription, initiation
IN838_RS06785	COG5662	AntiSigma factor
IN838_RS06790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IN838_RS06860	COG0598	Magnesium transport protein CorA
IN838_RS06865	COG1309	transcriptional regulator
IN838_RS06885	COG2095	MarC family integral membrane protein
IN838_RS06900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN838_RS06905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN838_RS06925	COG3835	regulator
IN838_RS06930	COG1073	alpha beta
IN838_RS06935	COG0567	Dehydrogenase, E1 component
IN838_RS06935	COG0508	dehydrogenase complex catalyzes the overall conversion of
IN838_RS06945	COG2814	Major facilitator Superfamily
IN838_RS07005	COG0277	FAD linked oxidase domain protein
IN838_RS07010	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS07025	COG0668	transmembrane transport
IN838_RS07115	COG2814	Major facilitator Superfamily
IN838_RS07145	COG0019	diaminopimelate decarboxylase activity
IN838_RS07150	COG0460	homoserine dehydrogenase
IN838_RS07155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IN838_RS07190	COG2890	protein-(glutamine-N5) methyltransferase activity
IN838_RS07200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IN838_RS07210	COG0356	it plays a direct role in the translocation of protons across the membrane
IN838_RS07215	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IN838_RS07240	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IN838_RS07300	COG0346	lactoylglutathione lyase activity
IN838_RS07305	COG0183	Belongs to the thiolase family
IN838_RS07310	COG2409	Drug exporters of the RND superfamily
IN838_RS07325	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IN838_RS07330	COG0366	Alpha amylase catalytic
IN838_RS07335	COG0058	SHG alpha-glucan phosphorylase activity
IN838_RS07350	COG1335	isochorismatase
IN838_RS07360	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IN838_RS07375	COG3191	aminopeptidase activity
IN838_RS07420	COG0604	alcohol dehydrogenase
IN838_RS07440	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS07455	COG0419	ATPase involved in DNA repair
IN838_RS07460	COG1024	Enoyl-CoA hydratase
IN838_RS07470	COG0243	molybdopterin cofactor binding
IN838_RS07485	COG2188	Transcriptional regulator
IN838_RS07540	COG0596	Alpha beta hydrolase
IN838_RS07545	COG3757	hydrolase, family 25
IN838_RS07560	COG1051	belongs to the nudix hydrolase family
IN838_RS07580	COG1309	transcriptional regulator
IN838_RS07595	COG4585	Histidine kinase
IN838_RS07600	COG2197	response regulator
IN838_RS07610	COG2239	Acts as a magnesium transporter
IN838_RS07620	COG0300	oxidoreductase activity
IN838_RS07630	COG0656	L-ascorbic acid biosynthetic process
IN838_RS07645	COG1376	ErfK ybiS ycfS ynhG family protein
IN838_RS07660	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IN838_RS07665	COG0433	COG0433 Predicted ATPase
IN838_RS07680	COG0300	oxidoreductase activity
IN838_RS07695	COG1301	dicarboxylic acid transport
IN838_RS07705	COG0531	amino acid
IN838_RS07725	COG4424	Sulfotransferase
IN838_RS07730	COG3119	arylsulfatase activity
IN838_RS07765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IN838_RS07765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IN838_RS07805	COG2902	Dehydrogenase
IN838_RS07810	COG0824	Thioesterase
IN838_RS07825	COG0366	Alpha amylase catalytic
IN838_RS07860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IN838_RS07880	COG1309	transcriptional regulator
IN838_RS07895	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IN838_RS07915	COG0740	serine-type endopeptidase activity
IN838_RS07920	COG0740	serine-type endopeptidase activity
IN838_RS07970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IN838_RS07980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IN838_RS07980	COG0674	pyruvate-flavodoxin oxidoreductase activity
IN838_RS07985	COG1013	pyruvate-flavodoxin oxidoreductase activity
IN838_RS07995	COG1388	LysM domain
IN838_RS08025	COG0525	valine-tRNA ligase activity
IN838_RS08030	COG0285	dihydrofolate synthase activity
IN838_RS08045	COG1530	ribonuclease E activity
IN838_RS08045	COG1530	ribonuclease E activity
IN838_RS08075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IN838_RS08095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN838_RS08100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IN838_RS08105	COG0542	response to heat
IN838_RS08115	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IN838_RS08125	COG0406	alpha-ribazole phosphatase activity
IN838_RS08130	COG2755	lipolytic protein G-D-S-L family
IN838_RS08150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN838_RS08185	COG2308	Evidence 4 Homologs of previously reported genes of
IN838_RS08195	COG1305	Transglutaminase-like
IN838_RS08225	COG3387	PFAM Glycoside hydrolase 15-related
IN838_RS08240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN838_RS08275	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IN838_RS08280	COG4208	sulfate ABC transporter
IN838_RS08340	COG0484	heat shock protein binding
IN838_RS08390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IN838_RS08420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IN838_RS08435	COG0076	glutamate decarboxylase activity
IN838_RS08470	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS08520	COG0423	glycine-tRNA ligase activity
IN838_RS08525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IN838_RS08530	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IN838_RS08550	COG0358	DNA primase activity
IN838_RS08615	COG0745	RESPONSE REGULATOR receiver
IN838_RS08620	COG5002	protein histidine kinase activity
IN838_RS09025	COG3179	chitinase
IN838_RS09250	COG0488	(ABC) transporter
IN838_RS09275	COG1960	acyl-CoA dehydrogenase activity
IN838_RS09280	COG1335	isochorismatase
IN838_RS09290	COG0058	SHG alpha-glucan phosphorylase activity
IN838_RS09330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN838_RS09335	COG1960	acyl-CoA dehydrogenase activity
IN838_RS09340	COG0183	Belongs to the thiolase family
IN838_RS09360	COG1228	amidohydrolase
IN838_RS09390	COG0604	alcohol dehydrogenase
IN838_RS09390	COG3321	synthase
IN838_RS09390	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS09410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IN838_RS09440	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IN838_RS09470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN838_RS09515	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
IN838_RS09520	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IN838_RS09580	COG0714	Associated with various cellular activities
IN838_RS09605	COG0557	exoribonuclease II activity
IN838_RS09615	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS09640	COG0174	glutamine synthetase
IN838_RS09645	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IN838_RS09675	COG2205	protein histidine kinase activity
IN838_RS09705	COG0174	glutamine synthetase
IN838_RS09715	COG0477	Major facilitator Superfamily
IN838_RS09725	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IN838_RS09745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IN838_RS09750	COG0321	lipoyl(octanoyl) transferase activity
IN838_RS09765	COG1872	DUF167
IN838_RS09785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IN838_RS09795	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IN838_RS09800	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IN838_RS09830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN838_RS09875	COG2010	Cytochrome c
IN838_RS09880	COG1845	cytochrome c oxidase, subunit III
IN838_RS09885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IN838_RS09920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IN838_RS09945	COG0003	Pfam Anion-transporting ATPase
IN838_RS09955	COG0204	Acyl-transferase
IN838_RS09960	COG5650	phosphatidylinositol metabolic process
IN838_RS09970	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IN838_RS09995	COG0142	geranyltranstransferase activity
IN838_RS10035	COG0768	penicillin binding
IN838_RS10055	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IN838_RS10065	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IN838_RS10080	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IN838_RS10105	COG0640	Transcriptional regulator
IN838_RS10160	COG0154	amidase activity
IN838_RS10170	COG2957	Belongs to the agmatine deiminase family
IN838_RS10180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IN838_RS10190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IN838_RS10200	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS10230	COG2814	Major facilitator Superfamily
IN838_RS10305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS10310	COG2030	dehydratase
IN838_RS10330	COG1024	Enoyl-CoA hydratase
IN838_RS10345	COG1309	transcriptional regulator
IN838_RS10365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IN838_RS10410	COG2072	flavoprotein involved in K transport
IN838_RS10425	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS10430	COG1960	acyl-CoA dehydrogenase activity
IN838_RS10450	COG1960	acyl-CoA dehydrogenase activity
IN838_RS10475	COG3621	Patatin-like phospholipase
IN838_RS10535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IN838_RS10565	COG1968	undecaprenyl-diphosphatase activity
IN838_RS10600	COG1218	3'(2'),5'-bisphosphate nucleotidase
IN838_RS10610	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS10635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IN838_RS10645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IN838_RS10645	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IN838_RS10660	COG2860	membrane
IN838_RS10670	COG1410	methionine synthase
IN838_RS10670	COG0646	methionine synthase
IN838_RS10675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IN838_RS10685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IN838_RS10720	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IN838_RS10725	COG1034	ATP synthesis coupled electron transport
IN838_RS10730	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IN838_RS10735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IN838_RS10815	COG0513	Belongs to the DEAD box helicase family
IN838_RS10850	COG0028	Belongs to the TPP enzyme family
IN838_RS10865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IN838_RS10870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IN838_RS10875	COG4122	O-methyltransferase activity
IN838_RS10905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IN838_RS10910	COG4521	taurine ABC transporter
IN838_RS10915	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IN838_RS10950	COG2378	regulation of single-species biofilm formation
IN838_RS10955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IN838_RS10990	COG0300	oxidoreductase activity
IN838_RS11045	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IN838_RS11055	COG0463	Glycosyl transferase, family 2
IN838_RS11060	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS11085	COG0604	alcohol dehydrogenase
IN838_RS11085	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS11085	COG3321	synthase
IN838_RS11105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IN838_RS11115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IN838_RS11120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS11140	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IN838_RS11150	COG1404	Belongs to the peptidase S8 family
IN838_RS11165	COG4842	Belongs to the WXG100 family
IN838_RS11195	COG0464	growth
IN838_RS11215	COG0583	DNA-binding transcription factor activity
IN838_RS11245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IN838_RS11250	COG1169	isochorismate synthase
IN838_RS11255	COG0789	Transcriptional regulator
IN838_RS11260	COG1021	2,3-dihydroxybenzoate-AMP ligase
IN838_RS11290	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IN838_RS11315	COG0300	oxidoreductase activity
IN838_RS11315	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS11315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IN838_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS11315	COG3321	synthase
IN838_RS11330	COG1132	(ABC) transporter
IN838_RS11335	COG2375	cellular response to nickel ion
IN838_RS11335	COG1132	(ABC) transporter
IN838_RS11340	COG0477	Major facilitator Superfamily
IN838_RS11345	COG5285	phytanoyl-CoA dioxygenase
IN838_RS11355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IN838_RS11360	COG0456	acetyltransferase
IN838_RS11375	COG2837	iron assimilation
IN838_RS11385	COG2186	Transcriptional regulator
IN838_RS11390	COG2807	transmembrane transport
IN838_RS11400	COG2409	Drug exporters of the RND superfamily
IN838_RS11405	COG3629	intracellular signal transduction
IN838_RS11410	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS11450	COG0475	glutathione-regulated potassium exporter activity
IN838_RS11520	COG0237	dephospho-CoA kinase activity
IN838_RS11520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IN838_RS11705	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IN838_RS11710	COG0072	phenylalanine-tRNA ligase activity
IN838_RS11710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IN838_RS11720	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IN838_RS11725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IN838_RS11730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IN838_RS11735	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IN838_RS11740	COG1438	arginine binding
IN838_RS11745	COG0137	argininosuccinate synthase activity
IN838_RS11785	COG2835	tetraacyldisaccharide 4'-kinase activity
IN838_RS11790	COG1309	transcriptional regulator
IN838_RS11795	COG2094	Belongs to the DNA glycosylase MPG family
IN838_RS11820	COG0647	UMP catabolic process
IN838_RS11835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IN838_RS11855	COG0504	CTP synthase activity
IN838_RS11860	COG0494	nUDIX hydrolase
IN838_RS11880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IN838_RS11895	COG1160	GTP binding
IN838_RS11905	COG1403	HNH endonuclease
IN838_RS11985	COG3976	FMN-binding domain protein
IN838_RS11985	COG1053	succinate dehydrogenase
IN838_RS12015	COG1960	acyl-CoA dehydrogenase activity
IN838_RS12075	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IN838_RS12075	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IN838_RS12090	COG1253	flavin adenine dinucleotide binding
IN838_RS12095	COG1253	flavin adenine dinucleotide binding
IN838_RS12105	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IN838_RS12160	COG0832	Belongs to the urease beta subunit family
IN838_RS12170	COG0830	nickel cation binding
IN838_RS12185	COG1252	NADH dehydrogenase
IN838_RS12195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS12230	COG0243	molybdopterin cofactor binding
IN838_RS12240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IN838_RS12255	COG1546	Belongs to the CinA family
IN838_RS12255	COG1058	Belongs to the CinA family
IN838_RS12265	COG4977	sequence-specific DNA binding
IN838_RS12270	COG1741	Belongs to the pirin family
IN838_RS12295	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IN838_RS12320	COG0277	FAD linked oxidase domain protein
IN838_RS12330	COG1309	transcriptional regulator
IN838_RS12345	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IN838_RS12350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IN838_RS12355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IN838_RS12380	COG4290	ribonuclease
IN838_RS12410	COG0791	NLP P60 protein
IN838_RS12410	COG3883	PFAM NLP P60 protein
IN838_RS12445	COG0477	Major facilitator Superfamily
IN838_RS12465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IN838_RS12470	COG0067	glutamate synthase
IN838_RS12470	COG0069	glutamate synthase activity
IN838_RS12470	COG0070	glutamate synthase
IN838_RS12495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IN838_RS12510	COG1960	acyl-CoA dehydrogenase activity
IN838_RS12525	COG0443	Heat shock 70 kDa protein
IN838_RS12530	COG0596	Alpha beta hydrolase
IN838_RS12550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IN838_RS12560	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IN838_RS12585	COG2890	protein-(glutamine-N5) methyltransferase activity
IN838_RS12655	COG1982	Orn Lys Arg decarboxylase major
IN838_RS12710	COG0028	Belongs to the TPP enzyme family
IN838_RS12720	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS12740	COG1309	transcriptional regulator
IN838_RS12745	COG2957	Belongs to the agmatine deiminase family
IN838_RS12750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN838_RS12765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IN838_RS12815	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IN838_RS12830	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IN838_RS12850	COG0640	Transcriptional regulator
IN838_RS12860	COG0798	PFAM Bile acid sodium symporter
IN838_RS12865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IN838_RS12870	COG0390	transport system, permease component
IN838_RS12890	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS12895	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN838_RS12950	COG0745	RESPONSE REGULATOR receiver
IN838_RS12955	COG2205	protein histidine kinase activity
IN838_RS12970	COG1917	Cupin 2, conserved barrel domain protein
IN838_RS12975	COG3707	response regulator
IN838_RS13015	COG3467	pyridoxamine 5'-phosphate
IN838_RS13020	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
IN838_RS13040	COG0640	Transcriptional regulator
IN838_RS13060	COG1309	transcriptional regulator
IN838_RS13065	COG2072	flavoprotein involved in K transport
IN838_RS13075	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS13080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IN838_RS13085	COG0561	phosphatase activity
IN838_RS13090	COG0673	inositol 2-dehydrogenase activity
IN838_RS13095	COG0738	Major facilitator superfamily
IN838_RS13180	COG1271	oxidase subunit
IN838_RS13185	COG1294	oxidase, subunit
IN838_RS13190	COG4988	ABC transporter
IN838_RS13195	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IN838_RS13220	COG1946	Acyl-CoA thioesterase
IN838_RS13265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IN838_RS13270	COG1846	Transcriptional regulator
IN838_RS13295	COG2072	flavoprotein involved in K transport
IN838_RS13300	COG0657	acetylesterase activity
IN838_RS13350	COG0483	inositol monophosphate 1-phosphatase activity
IN838_RS13360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IN838_RS13365	COG0131	Imidazoleglycerol-phosphate dehydratase
IN838_RS13370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IN838_RS13395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IN838_RS13410	COG1309	transcriptional regulator
IN838_RS13425	COG0583	DNA-binding transcription factor activity
IN838_RS13430	COG0579	oxidoreductase
IN838_RS13470	COG2755	lipolytic protein G-D-S-L family
IN838_RS13470	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IN838_RS13525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IN838_RS13545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IN838_RS13550	COG2814	Major facilitator Superfamily
IN838_RS13555	COG0583	DNA-binding transcription factor activity
IN838_RS13605	COG2239	Acts as a magnesium transporter
IN838_RS13635	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IN838_RS13645	COG2304	oxidoreductase activity
IN838_RS13655	COG0714	Associated with various cellular activities
IN838_RS13665	COG3883	PFAM NLP P60 protein
IN838_RS13665	COG0791	NLP P60 protein
IN838_RS13675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IN838_RS13680	COG1309	transcriptional regulator
IN838_RS13705	COG0488	(ABC) transporter
IN838_RS13720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IN838_RS13735	COG0456	acetyltransferase
IN838_RS13745	COG2151	metal-sulfur cluster biosynthetic enzyme
IN838_RS13760	COG0396	ATPase activity
IN838_RS13785	COG1131	(ABC) transporter
IN838_RS13825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IN838_RS13845	COG0583	DNA-binding transcription factor activity
IN838_RS13850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN838_RS13920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IN838_RS13980	COG0531	amino acid
IN838_RS14035	COG2011	ABC-type metal ion transport system permease component
IN838_RS14040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IN838_RS14060	COG0477	Major facilitator Superfamily
IN838_RS14095	COG0657	acetylesterase activity
IN838_RS14100	COG1953	Uracil, thiamine, allantoin
IN838_RS14110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IN838_RS14115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN838_RS14125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IN838_RS14135	COG1758	RNA polymerase activity
IN838_RS14155	COG0284	orotidine-5'-phosphate decarboxylase activity
IN838_RS14160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IN838_RS14165	COG0505	Belongs to the CarA family
IN838_RS14185	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IN838_RS14205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IN838_RS14215	COG0006	proline dipeptidase activity
IN838_RS14230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IN838_RS14235	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IN838_RS14250	COG4106	trans-aconitate 2-methyltransferase activity
IN838_RS14265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IN838_RS14280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IN838_RS14330	COG0701	Predicted permease
IN838_RS14355	COG2272	Belongs to the type-B carboxylesterase lipase family
IN838_RS14395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IN838_RS14405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IN838_RS14415	COG0747	negative chemotaxis
IN838_RS14420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IN838_RS14435	COG2255	four-way junction helicase activity
IN838_RS14445	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IN838_RS14480	COG1946	Acyl-CoA thioesterase
IN838_RS14485	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IN838_RS14495	COG0438	transferase activity, transferring glycosyl groups
IN838_RS14535	COG4762	Protein conserved in bacteria
IN838_RS14590	COG1309	transcriptional regulator
IN838_RS14615	COG3878	Protein conserved in bacteria
IN838_RS14655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN838_RS14670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IN838_RS14670	COG2080	2 iron, 2 sulfur cluster binding
IN838_RS14685	COG0402	S-adenosylhomocysteine deaminase activity
IN838_RS14705	COG2233	PERMEase
IN838_RS14725	COG1953	Uracil, thiamine, allantoin
IN838_RS14735	COG1301	dicarboxylic acid transport
IN838_RS14745	COG4266	Belongs to the allantoicase family
IN838_RS14775	COG2267	carboxylic ester hydrolase activity
IN838_RS14780	COG1960	acyl-CoA dehydrogenase activity
IN838_RS14785	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS14800	COG0183	Belongs to the thiolase family
IN838_RS14830	COG0477	Major facilitator Superfamily
IN838_RS14885	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN838_RS14895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IN838_RS14935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IN838_RS14960	COG3253	May function as heme-dependent peroxidase
IN838_RS14965	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IN838_RS14970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IN838_RS14980	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IN838_RS14995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IN838_RS15000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IN838_RS15005	COG0531	amino acid
IN838_RS15010	COG0569	domain protein
IN838_RS15040	COG0702	epimerase
IN838_RS15055	COG0756	dUTP diphosphatase activity
IN838_RS15100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IN838_RS15150	COG3220	belongs to the UPF0276 family
IN838_RS15225	COG1388	LysM domain
IN838_RS15240	COG1960	acyl-CoA dehydrogenase activity
IN838_RS15250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IN838_RS15270	COG1196	nuclear chromosome segregation
IN838_RS15290	COG1126	abc transporter atp-binding protein
IN838_RS15295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN838_RS15300	COG0765	amino acid transport
IN838_RS15305	COG0765	amino acid transport
IN838_RS15355	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
IN838_RS15360	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
IN838_RS15375	COG1842	Phage shock protein A
IN838_RS15380	COG1396	sequence-specific DNA binding
IN838_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS15400	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IN838_RS15455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IN838_RS15460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IN838_RS15475	COG3214	Protein conserved in bacteria
IN838_RS15515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IN838_RS15525	COG0659	secondary active sulfate transmembrane transporter activity
IN838_RS15535	COG0686	Belongs to the AlaDH PNT family
IN838_RS15550	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS15620	COG2977	Belongs to the P-Pant transferase superfamily
IN838_RS15625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IN838_RS15645	COG1960	acyl-CoA dehydrogenase activity
IN838_RS15650	COG1960	acyl-CoA dehydrogenase activity
IN838_RS15655	COG1024	Enoyl-CoA hydratase
IN838_RS15680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IN838_RS15705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN838_RS15705	COG1017	nitric oxide dioxygenase activity
IN838_RS15710	COG1959	2 iron, 2 sulfur cluster binding
IN838_RS15755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IN838_RS15755	COG1648	precorrin-2 dehydrogenase activity
IN838_RS15780	COG0604	alcohol dehydrogenase
IN838_RS15780	COG3321	synthase
IN838_RS15780	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS15840	COG0579	oxidoreductase
IN838_RS15860	COG1492	cobalamin metabolic process
IN838_RS15870	COG1376	ErfK ybiS ycfS ynhG family protein
IN838_RS15895	COG0750	zinc metalloprotease
IN838_RS15920	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IN838_RS15985	COG0528	UMP kinase activity
IN838_RS15990	COG3973	AAA domain
IN838_RS16005	COG2723	6-phospho-beta-galactosidase activity
IN838_RS16040	COG1309	transcriptional regulator
IN838_RS16080	COG0583	DNA-binding transcription factor activity
IN838_RS16105	COG0792	nuclease activity
IN838_RS16165	COG0336	Belongs to the RNA methyltransferase TrmD family
IN838_RS16205	COG1686	Belongs to the peptidase S11 family
IN838_RS16225	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IN838_RS16245	COG1304	FMN binding
IN838_RS16270	COG1254	Belongs to the acylphosphatase family
IN838_RS16295	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IN838_RS16300	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IN838_RS16320	COG0571	ribonuclease III activity
IN838_RS16330	COG3599	regulation of cell shape
IN838_RS16370	COG0742	ribosomal rna small subunit methyltransferase
IN838_RS16375	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IN838_RS16390	COG0657	acetylesterase activity
IN838_RS16395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS16415	COG2124	cytochrome p450
IN838_RS16430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IN838_RS16435	COG1461	Dihydroxyacetone kinase
IN838_RS16445	COG1024	Enoyl-CoA hydratase
IN838_RS16470	COG1181	Belongs to the D-alanine--D-alanine ligase family
IN838_RS16475	COG0626	cystathionine gamma-synthase activity
IN838_RS16480	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IN838_RS16545	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN838_RS16560	COG2271	Major facilitator Superfamily
IN838_RS16595	COG0583	DNA-binding transcription factor activity
IN838_RS16605	COG0778	Nitroreductase
IN838_RS16620	COG1309	transcriptional regulator
IN838_RS16625	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN838_RS16630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN838_RS16635	COG2124	cytochrome p450
IN838_RS16665	COG0440	acetolactate synthase activity
IN838_RS16680	COG1748	Saccharopine dehydrogenase
IN838_RS16685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IN838_RS16705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN838_RS16725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IN838_RS16735	COG2272	Belongs to the type-B carboxylesterase lipase family
IN838_RS16750	COG0745	RESPONSE REGULATOR receiver
IN838_RS16755	COG2205	protein histidine kinase activity
IN838_RS16780	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IN838_RS16810	COG1024	Enoyl-CoA hydratase
IN838_RS16815	COG0778	Nitroreductase
IN838_RS16825	COG2252	PERMEase
IN838_RS16865	COG2197	response regulator
IN838_RS16870	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IN838_RS16880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IN838_RS16905	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IN838_RS16920	COG1309	transcriptional regulator
IN838_RS16950	COG0110	maltose O-acetyltransferase activity
IN838_RS16955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IN838_RS16980	COG1119	ATPase activity
IN838_RS16990	COG2364	Membrane
IN838_RS16995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IN838_RS17010	COG4607	ABC-type enterochelin transport system periplasmic component
IN838_RS17060	COG1064	alcohol dehydrogenase
IN838_RS17080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IN838_RS17085	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS17220	COG1335	isochorismatase
IN838_RS17230	COG2855	membrane
IN838_RS17240	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS17255	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS17265	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS17270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IN838_RS17330	COG2272	Belongs to the type-B carboxylesterase lipase family
IN838_RS17345	COG0183	Belongs to the thiolase family
IN838_RS17380	COG1309	transcriptional regulator
IN838_RS17410	COG0789	Transcriptional regulator
IN838_RS17420	COG0028	Belongs to the TPP enzyme family
IN838_RS17445	COG2177	Part of the ABC transporter FtsEX involved in
IN838_RS17450	COG2884	Cell division ATP-binding protein ftsE
IN838_RS17460	COG0668	transmembrane transport
IN838_RS17500	COG0483	inositol monophosphate 1-phosphatase activity
IN838_RS17505	COG1960	acyl-CoA dehydrogenase activity
IN838_RS17510	COG1960	acyl-CoA dehydrogenase activity
IN838_RS17525	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS17535	COG0542	response to heat
IN838_RS17580	COG3480	Lon protease (S16) C-terminal proteolytic domain
IN838_RS17585	COG3011	Protein conserved in bacteria
IN838_RS17600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN838_RS17605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN838_RS17615	COG0300	oxidoreductase activity
IN838_RS17620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN838_RS17655	COG0475	glutathione-regulated potassium exporter activity
IN838_RS17655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IN838_RS17670	COG0596	Alpha beta hydrolase
IN838_RS17685	COG0745	RESPONSE REGULATOR receiver
IN838_RS17695	COG2146	nitrite reductase [NAD(P)H] activity
IN838_RS17695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IN838_RS17700	COG2223	nitrite transmembrane transporter activity
IN838_RS17740	COG0513	Belongs to the DEAD box helicase family
IN838_RS17755	COG0406	alpha-ribazole phosphatase activity
IN838_RS17775	COG1597	lipid kinase activity
IN838_RS17790	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IN838_RS17800	COG1595	DNA-templated transcription, initiation
IN838_RS17805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IN838_RS17810	COG2135	peptidase activity
IN838_RS17815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IN838_RS17820	COG1162	GTPase activity
IN838_RS17855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IN838_RS17950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IN838_RS17955	COG0604	alcohol dehydrogenase
IN838_RS17955	COG3321	synthase
IN838_RS17960	COG0604	alcohol dehydrogenase
IN838_RS17960	COG3321	synthase
IN838_RS17965	COG1960	acyl-CoA dehydrogenase activity
IN838_RS17975	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS17980	COG0653	protein targeting
IN838_RS17990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IN838_RS17995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IN838_RS18005	COG1309	transcriptional regulator
IN838_RS18020	COG5401	PFAM Sporulation and spore germination
IN838_RS18025	COG5002	protein histidine kinase activity
IN838_RS18035	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS18040	COG1285	pathogenesis
IN838_RS18070	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IN838_RS18075	COG0531	amino acid
IN838_RS18085	COG1482	cell wall glycoprotein biosynthetic process
IN838_RS18115	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IN838_RS18120	COG0778	Nitroreductase
IN838_RS18120	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IN838_RS18135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IN838_RS18150	COG1316	TRANSCRIPTIONal
IN838_RS18170	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IN838_RS18180	COG2175	clavaminate synthase activity
IN838_RS18205	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IN838_RS18205	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IN838_RS18215	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS18230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IN838_RS18250	COG3265	gluconokinase activity
IN838_RS18255	COG1960	acyl-CoA dehydrogenase activity
IN838_RS18270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS18290	COG4770	biotin carboxylase activity
IN838_RS18300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IN838_RS18320	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS18325	COG1309	transcriptional regulator
IN838_RS18330	COG1201	RNA secondary structure unwinding
IN838_RS18345	COG0564	pseudouridine synthase activity
IN838_RS18365	COG1473	amidohydrolase
IN838_RS18365	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IN838_RS18380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IN838_RS18395	COG0791	NLP P60 protein
IN838_RS18395	COG3883	PFAM NLP P60 protein
IN838_RS18440	COG2009	succinate dehydrogenase
IN838_RS18455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IN838_RS18460	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IN838_RS18465	COG1595	DNA-templated transcription, initiation
IN838_RS18480	COG1686	Belongs to the peptidase S11 family
IN838_RS18495	COG0708	Exodeoxyribonuclease III
IN838_RS18555	COG1733	regulation of RNA biosynthetic process
IN838_RS18560	COG2910	NAD(P)H-binding
IN838_RS18565	COG0842	Transport permease protein
IN838_RS18565	COG1716	ATPase activity
IN838_RS18565	COG1131	(ABC) transporter
IN838_RS18570	COG1357	PFAM Pentapeptide repeats (8 copies)
IN838_RS18585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IN838_RS18590	COG0587	DNA-directed DNA polymerase activity
IN838_RS18595	COG1073	alpha beta
IN838_RS18600	COG1309	transcriptional regulator
IN838_RS18665	COG0519	Catalyzes the synthesis of GMP from XMP
IN838_RS18665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IN838_RS18675	COG0516	GMP reductase activity
IN838_RS18735	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IN838_RS18750	COG0456	acetyltransferase
IN838_RS18770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IN838_RS18775	COG0076	glutamate decarboxylase activity
IN838_RS18785	COG2267	carboxylic ester hydrolase activity
IN838_RS18790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IN838_RS18815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS18825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IN838_RS18830	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IN838_RS18865	COG1404	Belongs to the peptidase S8 family
IN838_RS18895	COG2267	carboxylic ester hydrolase activity
IN838_RS18950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IN838_RS18955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN838_RS18965	COG2268	Band 7 protein
IN838_RS18975	COG1088	dTDP-glucose 4,6-dehydratase activity
IN838_RS18980	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IN838_RS19025	COG0616	signal peptide processing
IN838_RS19040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS19060	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IN838_RS19070	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IN838_RS19080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IN838_RS19095	COG2272	Belongs to the type-B carboxylesterase lipase family
IN838_RS19120	COG0477	Major facilitator Superfamily
IN838_RS19135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IN838_RS19175	COG0088	Forms part of the polypeptide exit tunnel
IN838_RS19180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IN838_RS19185	COG0051	transcription antitermination factor activity, RNA binding
IN838_RS19220	COG0531	amino acid
IN838_RS19250	COG0535	radical SAM domain protein
IN838_RS19275	COG1834	amidinotransferase
IN838_RS19280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IN838_RS19285	COG0531	amino acid
IN838_RS19330	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IN838_RS19335	COG1309	transcriptional regulator
IN838_RS19360	COG1024	Enoyl-CoA hydratase
IN838_RS19375	COG1960	acyl-CoA dehydrogenase activity
IN838_RS19405	COG1113	amino acid transport
IN838_RS19420	COG0085	RNA polymerase activity
IN838_RS19425	COG0243	molybdopterin cofactor binding
IN838_RS19480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IN838_RS19495	COG0277	FAD linked oxidase domain protein
IN838_RS19515	COG4941	Belongs to the sigma-70 factor family
IN838_RS19550	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IN838_RS19590	COG0783	Belongs to the Dps family
IN838_RS19595	COG0693	protein deglycase activity
IN838_RS19640	COG1404	Belongs to the peptidase S8 family
IN838_RS19660	COG1280	lysine exporter protein (LysE YggA)
IN838_RS19730	COG0501	Belongs to the peptidase M48B family
IN838_RS19735	COG0142	geranyltranstransferase activity
IN838_RS19740	COG0644	oxidoreductase
IN838_RS19750	COG0438	transferase activity, transferring glycosyl groups
IN838_RS19770	COG4948	Mandelate Racemase Muconate Lactonizing
IN838_RS19795	COG3706	GGDEF domain
IN838_RS19810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IN838_RS19820	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IN838_RS19825	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS19830	COG4221	oxidoreductase activity
IN838_RS19880	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IN838_RS19885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IN838_RS19925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IN838_RS19970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IN838_RS19975	COG1333	cytochrome c biogenesis protein
IN838_RS19980	COG0785	Cytochrome C biogenesis protein
IN838_RS19990	COG0406	alpha-ribazole phosphatase activity
IN838_RS20010	COG3590	peptidase
IN838_RS20060	COG1587	Uroporphyrinogen-III synthase
IN838_RS20060	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IN838_RS20085	COG2030	dehydratase
IN838_RS20110	COG2070	2-Nitropropane dioxygenase
IN838_RS20135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IN838_RS20140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN838_RS20245	COG1309	transcriptional regulator
IN838_RS20255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN838_RS20305	COG2072	flavoprotein involved in K transport
IN838_RS20320	COG2072	flavoprotein involved in K transport
IN838_RS20325	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS20330	COG0657	acetylesterase activity
IN838_RS20335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN838_RS20345	COG0745	RESPONSE REGULATOR receiver
IN838_RS20350	COG5002	protein histidine kinase activity
IN838_RS20360	COG2072	flavoprotein involved in K transport
IN838_RS20375	COG0300	oxidoreductase activity
IN838_RS20430	COG2814	Major facilitator Superfamily
IN838_RS20435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IN838_RS20530	COG2733	membrane
IN838_RS20540	COG2326	polyphosphate kinase activity
IN838_RS20545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IN838_RS20580	COG2224	Isocitrate lyase
IN838_RS20620	COG2226	methyltransferase
IN838_RS20670	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IN838_RS20705	COG0667	Aldo Keto reductase
IN838_RS20730	COG4552	Acetyltransferase involved in intracellular survival and related
IN838_RS20735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS20760	COG1505	serine-type exopeptidase activity
IN838_RS20780	COG1073	alpha beta
IN838_RS20785	COG2326	polyphosphate kinase activity
IN838_RS20800	COG2223	nitrite transmembrane transporter activity
IN838_RS20805	COG0640	Transcriptional regulator
IN838_RS20835	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IN838_RS20855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IN838_RS20880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN838_RS20885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN838_RS20890	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS20900	COG1960	acyl-CoA dehydrogenase activity
IN838_RS20905	COG1960	acyl-CoA dehydrogenase activity
IN838_RS20910	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS20920	COG2070	2-Nitropropane dioxygenase
IN838_RS20930	COG1024	Enoyl-CoA hydratase
IN838_RS20935	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IN838_RS20940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS20975	COG4638	Rieske (2fe-2S)
IN838_RS21015	COG0175	sulfate reduction
IN838_RS21085	COG2814	Major facilitator Superfamily
IN838_RS21095	COG0351	phosphomethylpyrimidine kinase
IN838_RS21105	COG1252	NADH dehydrogenase
IN838_RS21115	COG1309	transcriptional regulator
IN838_RS21125	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS21160	COG0494	nUDIX hydrolase
IN838_RS21170	COG2234	aminopeptidase activity
IN838_RS21175	COG2234	aminopeptidase activity
IN838_RS21185	COG1131	(ABC) transporter
IN838_RS21190	COG2022	thiamine diphosphate biosynthetic process
IN838_RS21225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN838_RS21230	COG0515	serine threonine protein kinase
IN838_RS21235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IN838_RS21265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IN838_RS21270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS21275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS21280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS21290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN838_RS21295	COG1126	abc transporter atp-binding protein
IN838_RS21335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IN838_RS21370	COG1994	Peptidase M50
IN838_RS21390	COG0586	Pfam SNARE associated Golgi protein
IN838_RS21420	COG4221	oxidoreductase activity
IN838_RS21440	COG0542	response to heat
IN838_RS21465	COG0789	Transcriptional regulator
IN838_RS21470	COG0484	heat shock protein binding
IN838_RS21475	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IN838_RS21545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IN838_RS21545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IN838_RS21585	COG2181	nitrate reductase activity
IN838_RS21585	COG0247	lactate metabolic process
IN838_RS21595	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IN838_RS21635	COG3345	alpha-galactosidase
IN838_RS21640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IN838_RS21645	COG1305	Transglutaminase-like
IN838_RS21660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IN838_RS21730	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS21740	COG0454	-acetyltransferase
IN838_RS21795	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS21800	COG1960	acyl-CoA dehydrogenase activity
IN838_RS21815	COG3268	Saccharopine dehydrogenase
IN838_RS21820	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS21825	COG1793	dna ligase
IN838_RS21825	COG3285	dna ligase
IN838_RS21830	COG0494	nUDIX hydrolase
IN838_RS21840	COG2902	Dehydrogenase
IN838_RS21845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IN838_RS21860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN838_RS21880	COG1309	transcriptional regulator
IN838_RS21895	COG0778	Nitroreductase
IN838_RS21900	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN838_RS21925	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN838_RS21930	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS21935	COG1396	sequence-specific DNA binding
IN838_RS21940	COG1414	Transcriptional regulator
IN838_RS21955	COG2267	carboxylic ester hydrolase activity
IN838_RS21960	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IN838_RS21975	COG4638	Rieske (2fe-2S)
IN838_RS21980	COG3321	synthase
IN838_RS21980	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS21980	COG0604	alcohol dehydrogenase
IN838_RS21985	COG3384	dioxygenase
IN838_RS21990	COG3971	2-oxopent-4-enoate hydratase activity
IN838_RS22005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IN838_RS22010	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS22045	COG1309	transcriptional regulator
IN838_RS22070	COG1309	transcriptional regulator
IN838_RS22075	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IN838_RS22090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IN838_RS22095	COG1984	allophanate hydrolase subunit 2
IN838_RS22160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IN838_RS22165	COG1802	Transcriptional regulator
IN838_RS22195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IN838_RS22205	COG0473	3-isopropylmalate dehydrogenase activity
IN838_RS22220	COG1053	succinate dehydrogenase
IN838_RS22240	COG0640	Transcriptional regulator
IN838_RS22290	COG2318	DinB family
IN838_RS22295	COG1960	acyl-CoA dehydrogenase activity
IN838_RS22310	COG1660	Displays ATPase and GTPase activities
IN838_RS22320	COG0183	Belongs to the thiolase family
IN838_RS22325	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS22330	COG2030	dehydratase
IN838_RS22345	COG0659	secondary active sulfate transmembrane transporter activity
IN838_RS22350	COG1309	transcriptional regulator
IN838_RS22355	COG0861	Integral membrane protein TerC family
IN838_RS22380	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS22395	COG1472	Belongs to the glycosyl hydrolase 3 family
IN838_RS22400	COG4941	Belongs to the sigma-70 factor family
IN838_RS22465	COG4981	capsule polysaccharide biosynthetic process
IN838_RS22505	COG0438	transferase activity, transferring glycosyl groups
IN838_RS22550	COG1250	3-hydroxyacyl-CoA dehydrogenase
IN838_RS22595	COG2197	response regulator
IN838_RS22600	COG3850	Histidine kinase
IN838_RS22620	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IN838_RS22650	COG2409	Drug exporters of the RND superfamily
IN838_RS22695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN838_RS22705	COG2197	response regulator
IN838_RS22735	COG2353	YceI-like domain
IN838_RS22750	COG2409	Drug exporters of the RND superfamily
IN838_RS22765	COG4552	Acetyltransferase involved in intracellular survival and related
IN838_RS22770	COG1832	CoA-binding protein
IN838_RS22785	COG3590	peptidase
IN838_RS22790	COG1376	ErfK ybiS ycfS ynhG family protein
IN838_RS22795	COG1960	acyl-CoA dehydrogenase activity
IN838_RS22805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IN838_RS22815	COG1937	Protein conserved in bacteria
IN838_RS22840	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS22845	COG4122	O-methyltransferase activity
IN838_RS22860	COG2267	carboxylic ester hydrolase activity
IN838_RS22890	COG1704	LemA family
IN838_RS22900	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS22955	COG1024	Enoyl-CoA hydratase
IN838_RS22960	COG1802	Transcriptional regulator
IN838_RS22970	COG2267	carboxylic ester hydrolase activity
IN838_RS22975	COG1309	transcriptional regulator
IN838_RS23005	COG0435	Glutathione S-transferase
IN838_RS23045	COG1024	Enoyl-CoA hydratase
IN838_RS23055	COG2211	Major facilitator Superfamily
IN838_RS23060	COG2365	Tyrosine phosphatase family
IN838_RS23125	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS23130	COG1012	belongs to the aldehyde dehydrogenase family
IN838_RS23145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IN838_RS23150	COG1960	acyl-CoA dehydrogenase activity
IN838_RS23155	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IN838_RS23170	COG2226	methyltransferase
IN838_RS23185	COG3800	Transcriptional regulator
IN838_RS23185	COG1396	sequence-specific DNA binding
IN838_RS23195	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IN838_RS23235	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS23295	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IN838_RS23305	COG0129	dihydroxy-acid dehydratase activity
IN838_RS23325	COG2186	Transcriptional regulator
IN838_RS23355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IN838_RS23360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN838_RS23370	COG0723	plastoquinol--plastocyanin reductase activity
IN838_RS23390	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS23430	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS23445	COG0318	PFAM AMP-dependent synthetase and ligase
IN838_RS23450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IN838_RS23455	COG1136	(ABC) transporter
IN838_RS23465	COG1104	cysteine desulfurase activity
IN838_RS23525	COG1309	transcriptional regulator
IN838_RS23535	COG1819	glycosyl
IN838_RS23580	COG1819	glycosyl
IN838_RS23695	COG3263	regulation of cellular component size
IN838_RS23775	COG1595	DNA-templated transcription, initiation
IN838_RS23785	COG0783	Belongs to the Dps family
IN838_RS23830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IN838_RS23850	COG1937	Protein conserved in bacteria
IN838_RS23875	COG1403	HNH endonuclease
IN838_RS23950	COG2140	Oxalate decarboxylase
IN838_RS23975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IN838_RS23995	COG1376	ErfK ybiS ycfS ynhG family protein
IN838_RS24015	COG2030	dehydratase
IN838_RS24020	COG0488	(ABC) transporter
IN838_RS24025	COG3757	hydrolase, family 25
IN838_RS24090	COG0583	DNA-binding transcription factor activity
IN838_RS24100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN838_RS24115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN838_RS24120	COG3757	hydrolase, family 25
IN838_RS24260	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IN838_RS24285	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IN838_RS24295	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IN838_RS24330	COG0454	-acetyltransferase
IN838_RS24375	COG0629	single-stranded DNA binding
IN838_RS24390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IN838_RS24420	COG1260	myo-inositol-1-phosphate synthase
IN838_RS24430	COG1113	amino acid transport
IN838_RS24445	COG1309	transcriptional regulator
IN838_RS24450	COG1028	Short-chain dehydrogenase reductase Sdr
IN838_RS24465	COG0508	dehydrogenase complex catalyzes the overall conversion of
IN838_RS24470	COG0022	dehydrogenase e1 component
IN838_RS24485	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IN838_RS24490	COG2311	Membrane
IN838_RS24555	COG0617	tRNA 3'-terminal CCA addition
IN838_RS24575	COG1595	DNA-templated transcription, initiation
IN838_RS24595	COG3409	Peptidoglycan-binding domain 1 protein
IN838_RS24595	COG0860	N-Acetylmuramoyl-L-alanine amidase
IN838_RS24605	COG2124	cytochrome p450
IN838_RS24615	COG1309	transcriptional regulator
IN838_RS24635	COG1192	Involved in chromosome partitioning
IN838_RS24640	COG0357	Ribosomal RNA small subunit methyltransferase G
IN838_RS24650	COG0706	membrane insertase activity
IN838_RS24655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane