locus-tag	class	description
IN839_RS00015	COG0592	DNA-directed DNA polymerase activity
IN839_RS00020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IN839_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IN839_RS00030	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
IN839_RS00035	COG0187	DNA topoisomerase II activity
IN839_RS00120	COG2814	Major facilitator Superfamily
IN839_RS00125	COG0583	DNA-binding transcription factor activity
IN839_RS00140	COG0457	Tetratricopeptide repeat
IN839_RS00140	COG0705	Rhomboid family
IN839_RS00175	COG0515	serine threonine protein kinase
IN839_RS00175	COG2815	serine threonine protein kinase
IN839_RS00180	COG0515	serine threonine protein kinase
IN839_RS00185	COG0768	penicillin binding
IN839_RS00200	COG1716	ATPase activity
IN839_RS00205	COG1716	ATPase activity
IN839_RS00220	COG0754	glutathionylspermidine amidase activity
IN839_RS00230	COG1309	transcriptional regulator
IN839_RS00250	COG4842	Belongs to the WXG100 family
IN839_RS00270	COG0590	tRNA wobble adenosine to inosine editing
IN839_RS00280	COG0583	DNA-binding transcription factor activity
IN839_RS00285	COG1643	Atp-dependent helicase
IN839_RS00290	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS00310	COG4585	Histidine kinase
IN839_RS00330	COG1960	acyl-CoA dehydrogenase activity
IN839_RS00375	COG2072	flavoprotein involved in K transport
IN839_RS00385	COG0346	lactoylglutathione lyase activity
IN839_RS00390	COG1414	Transcriptional regulator
IN839_RS00410	COG1053	succinate dehydrogenase
IN839_RS00440	COG1785	Belongs to the alkaline phosphatase family
IN839_RS00460	COG0069	glutamate synthase activity
IN839_RS00460	COG0070	glutamate synthase
IN839_RS00460	COG0067	glutamate synthase
IN839_RS00490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IN839_RS00490	COG1796	DNA polymerase
IN839_RS00500	COG2072	flavoprotein involved in K transport
IN839_RS00510	COG2124	cytochrome p450
IN839_RS00525	COG1024	Enoyl-CoA hydratase
IN839_RS00555	COG2372	response to copper ion
IN839_RS00605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IN839_RS00625	COG5002	protein histidine kinase activity
IN839_RS00625	COG5001	Diguanylate cyclase
IN839_RS00625	COG3447	MASE1 domain protein
IN839_RS00635	COG1528	Iron-storage protein
IN839_RS00640	COG1528	Iron-storage protein
IN839_RS00645	COG1316	TRANSCRIPTIONal
IN839_RS00670	COG0406	alpha-ribazole phosphatase activity
IN839_RS00680	COG0028	Belongs to the TPP enzyme family
IN839_RS00710	COG2072	flavoprotein involved in K transport
IN839_RS00720	COG2072	flavoprotein involved in K transport
IN839_RS00740	COG1285	pathogenesis
IN839_RS00790	COG2146	nitrite reductase [NAD(P)H] activity
IN839_RS00790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IN839_RS00800	COG4133	protoheme IX ABC transporter activity
IN839_RS00805	COG2070	2-Nitropropane dioxygenase
IN839_RS00810	COG1942	4-Oxalocrotonate Tautomerase
IN839_RS00815	COG0583	DNA-binding transcription factor activity
IN839_RS00830	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS00845	COG0561	phosphatase activity
IN839_RS00865	COG1216	Glycosyl transferase, family 2
IN839_RS00870	COG0671	phosphoesterase, PA-phosphatase related
IN839_RS00875	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IN839_RS00880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IN839_RS00900	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
IN839_RS00905	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS00910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IN839_RS00910	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IN839_RS00910	COG3321	synthase
IN839_RS00915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IN839_RS00965	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS00970	COG0277	FAD linked oxidase domain protein
IN839_RS00980	COG2376	Dihydroxyacetone kinase
IN839_RS00985	COG2267	carboxylic ester hydrolase activity
IN839_RS00990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IN839_RS00995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IN839_RS01010	COG0671	phosphoesterase, PA-phosphatase related
IN839_RS01020	COG1216	Glycosyl transferase, family 2
IN839_RS01100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IN839_RS01105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IN839_RS01175	COG1960	acyl-CoA dehydrogenase activity
IN839_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS01215	COG1174	glycine betaine transport
IN839_RS01230	COG0287	Prephenate dehydrogenase
IN839_RS01240	COG0590	tRNA wobble adenosine to inosine editing
IN839_RS01280	COG0343	queuine tRNA-ribosyltransferase activity
IN839_RS01290	COG0765	amino acid transport
IN839_RS01295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IN839_RS01300	COG1793	dna ligase
IN839_RS01330	COG2271	Major facilitator Superfamily
IN839_RS01335	COG2130	NADP-dependent
IN839_RS01360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IN839_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS01435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IN839_RS01460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IN839_RS01470	COG0148	phosphopyruvate hydratase activity
IN839_RS01500	COG0860	N-Acetylmuramoyl-L-alanine amidase
IN839_RS01525	COG1492	cobalamin metabolic process
IN839_RS01550	COG1960	acyl-CoA dehydrogenase activity
IN839_RS01565	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IN839_RS01595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IN839_RS01615	COG1231	oxidoreductase activity
IN839_RS01645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IN839_RS01655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IN839_RS01685	COG2070	2-Nitropropane dioxygenase
IN839_RS01730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IN839_RS01735	COG2971	BadF BadG BcrA BcrD
IN839_RS01740	COG2814	Major facilitator Superfamily
IN839_RS01760	COG3572	ergothioneine biosynthetic process
IN839_RS01765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IN839_RS01770	COG0121	glutamine amidotransferase
IN839_RS01775	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IN839_RS01780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IN839_RS01805	COG0183	Belongs to the thiolase family
IN839_RS01810	COG2030	dehydratase
IN839_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS01820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IN839_RS01830	COG1695	Transcriptional regulator
IN839_RS01840	COG0569	domain protein
IN839_RS01840	COG0475	glutathione-regulated potassium exporter activity
IN839_RS01860	COG0714	Associated with various cellular activities
IN839_RS01905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IN839_RS01910	COG1074	ATP-dependent DNA helicase activity
IN839_RS01915	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IN839_RS01925	COG2755	lipolytic protein G-D-S-L family
IN839_RS01955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IN839_RS01960	COG1408	metallophosphoesterase
IN839_RS01965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IN839_RS01995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IN839_RS02035	COG0596	Alpha beta hydrolase
IN839_RS02035	COG2945	thiolester hydrolase activity
IN839_RS02050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IN839_RS02055	COG0747	negative chemotaxis
IN839_RS02065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IN839_RS02135	COG0582	viral genome integration into host DNA
IN839_RS02180	COG2217	Heavy metal translocating P-type atpase
IN839_RS02190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IN839_RS02250	COG2132	Multicopper oxidase
IN839_RS02285	COG0596	Alpha beta hydrolase
IN839_RS02345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN839_RS02350	COG1309	transcriptional regulator
IN839_RS02355	COG0657	acetylesterase activity
IN839_RS02360	COG1902	pentaerythritol trinitrate reductase activity
IN839_RS02365	COG1205	dead DEAH box helicase
IN839_RS02365	COG1111	helicase
IN839_RS02370	COG1278	Cold shock
IN839_RS02380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IN839_RS02380	COG1754	DNA topoisomerase type I activity
IN839_RS02390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IN839_RS02500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IN839_RS02535	COG2027	D-alanyl-D-alanine carboxypeptidase
IN839_RS02570	COG1063	alcohol dehydrogenase
IN839_RS02580	COG2267	carboxylic ester hydrolase activity
IN839_RS02590	COG1309	transcriptional regulator
IN839_RS02605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IN839_RS02650	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IN839_RS02660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IN839_RS02680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IN839_RS02685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IN839_RS02725	COG4977	sequence-specific DNA binding
IN839_RS02730	COG1194	a g-specific adenine glycosylase
IN839_RS02740	COG1316	TRANSCRIPTIONal
IN839_RS02750	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IN839_RS02760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IN839_RS02780	COG1329	Transcriptional regulator
IN839_RS02785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IN839_RS02795	COG0215	cysteine-tRNA ligase activity
IN839_RS02805	COG0584	glycerophosphoryl diester phosphodiesterase
IN839_RS02815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IN839_RS02820	COG1120	ATPase activity
IN839_RS02825	COG0803	Belongs to the bacterial solute-binding protein 9 family
IN839_RS02835	COG1309	transcriptional regulator
IN839_RS02840	COG1960	acyl-CoA dehydrogenase activity
IN839_RS02855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN839_RS02865	COG0346	lactoylglutathione lyase activity
IN839_RS02905	COG1960	acyl-CoA dehydrogenase activity
IN839_RS02910	COG1960	acyl-CoA dehydrogenase activity
IN839_RS02915	COG1960	acyl-CoA dehydrogenase activity
IN839_RS02920	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS02925	COG1960	acyl-CoA dehydrogenase activity
IN839_RS02940	COG0183	Belongs to the thiolase family
IN839_RS02970	COG1024	Enoyl-CoA hydratase
IN839_RS02975	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS03000	COG0183	Belongs to the thiolase family
IN839_RS03010	COG1960	acyl-CoA dehydrogenase activity
IN839_RS03015	COG1960	acyl-CoA dehydrogenase activity
IN839_RS03020	COG2030	dehydratase
IN839_RS03045	COG2030	dehydratase
IN839_RS03050	COG1053	succinate dehydrogenase
IN839_RS03060	COG3971	2-oxopent-4-enoate hydratase activity
IN839_RS03105	COG0651	ATP synthesis coupled electron transport
IN839_RS03115	COG2111	Na H antiporter
IN839_RS03115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IN839_RS03120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IN839_RS03140	COG0647	UMP catabolic process
IN839_RS03165	COG4221	oxidoreductase activity
IN839_RS03185	COG0459	protein refolding
IN839_RS03200	COG0714	Associated with various cellular activities
IN839_RS03250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IN839_RS03265	COG4842	Belongs to the WXG100 family
IN839_RS03310	COG0745	RESPONSE REGULATOR receiver
IN839_RS03315	COG5000	phosphorelay sensor kinase activity
IN839_RS03315	COG5002	protein histidine kinase activity
IN839_RS03320	COG0537	adenosine 5'-monophosphoramidase activity
IN839_RS03325	COG0697	spore germination
IN839_RS03335	COG0596	Alpha beta hydrolase
IN839_RS03365	COG0436	Aminotransferase
IN839_RS03375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IN839_RS03400	COG0477	Major facilitator Superfamily
IN839_RS03405	COG0386	Belongs to the glutathione peroxidase family
IN839_RS03415	COG3573	Dehydrogenase
IN839_RS03425	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IN839_RS03440	COG2837	iron assimilation
IN839_RS03445	COG1362	aminopeptidase activity
IN839_RS03525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IN839_RS03535	COG0601	transmembrane transport
IN839_RS03540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IN839_RS03545	COG4172	Belongs to the ABC transporter superfamily
IN839_RS03575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IN839_RS03585	COG0354	folic acid binding
IN839_RS03635	COG2897	thiosulfate sulfurtransferase activity
IN839_RS03655	COG0745	RESPONSE REGULATOR receiver
IN839_RS03675	COG0581	inorganic phosphate transmembrane transporter activity
IN839_RS03680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IN839_RS03685	COG0604	alcohol dehydrogenase
IN839_RS03740	COG1250	3-hydroxyacyl-CoA dehydrogenase
IN839_RS03765	COG0697	spore germination
IN839_RS03785	COG0442	prolyl-tRNA aminoacylation
IN839_RS03790	COG2814	Major facilitator Superfamily
IN839_RS04000	COG5651	PPE family
IN839_RS04005	COG0436	Aminotransferase
IN839_RS04025	COG0531	amino acid
IN839_RS04030	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IN839_RS04035	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS04045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN839_RS04050	COG2902	Dehydrogenase
IN839_RS04055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IN839_RS04060	COG1960	acyl-CoA dehydrogenase activity
IN839_RS04065	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS04070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN839_RS04080	COG0657	acetylesterase activity
IN839_RS04085	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS04100	COG1902	pentaerythritol trinitrate reductase activity
IN839_RS04105	COG1902	pentaerythritol trinitrate reductase activity
IN839_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS04135	COG1024	Enoyl-CoA hydratase
IN839_RS04180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN839_RS04185	COG0657	acetylesterase activity
IN839_RS04205	COG0183	Belongs to the thiolase family
IN839_RS04220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN839_RS04240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN839_RS04255	COG1061	Type III restriction enzyme res subunit
IN839_RS04290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IN839_RS04315	COG1278	Cold shock
IN839_RS04355	COG2814	Major facilitator Superfamily
IN839_RS04425	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IN839_RS04430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IN839_RS04460	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS04460	COG2030	dehydratase
IN839_RS04465	COG1309	transcriptional regulator
IN839_RS04475	COG1024	Enoyl-CoA hydratase
IN839_RS04480	COG1250	3-hydroxyacyl-CoA dehydrogenase
IN839_RS04490	COG3396	Phenylacetate-CoA oxygenase
IN839_RS04495	COG3460	Phenylacetate-CoA oxygenase
IN839_RS04500	COG3396	Phenylacetate-CoA oxygenase
IN839_RS04505	COG2151	metal-sulfur cluster biosynthetic enzyme
IN839_RS04510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN839_RS04535	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN839_RS04545	COG2124	cytochrome p450
IN839_RS04575	COG1764	response to oxidative stress
IN839_RS04580	COG1846	Transcriptional regulator
IN839_RS04585	COG1216	Glycosyl transferase, family 2
IN839_RS04590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IN839_RS04620	COG0259	pyridoxamine-phosphate oxidase activity
IN839_RS04630	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS04635	COG5651	PPE family
IN839_RS04640	COG2409	Drug exporters of the RND superfamily
IN839_RS04665	COG4977	sequence-specific DNA binding
IN839_RS04690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS04700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IN839_RS04705	COG0833	amino acid
IN839_RS04720	COG2186	Transcriptional regulator
IN839_RS04725	COG0545	Peptidyl-prolyl cis-trans isomerase
IN839_RS04765	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IN839_RS04770	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IN839_RS04815	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS04830	COG3022	response to hydroperoxide
IN839_RS04840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IN839_RS04875	COG1309	transcriptional regulator
IN839_RS04910	COG1393	Belongs to the ArsC family
IN839_RS04915	COG0583	DNA-binding transcription factor activity
IN839_RS04955	COG0183	Belongs to the thiolase family
IN839_RS05000	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN839_RS05040	COG0438	transferase activity, transferring glycosyl groups
IN839_RS05045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IN839_RS05060	COG2382	esterase
IN839_RS05090	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
IN839_RS05095	COG1846	Transcriptional regulator
IN839_RS05145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IN839_RS05155	COG2326	polyphosphate kinase activity
IN839_RS05170	COG2084	Dehydrogenase
IN839_RS05185	COG0523	cobalamin synthesis protein
IN839_RS05190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IN839_RS05195	COG0235	Class ii aldolase
IN839_RS05200	COG1396	sequence-specific DNA binding
IN839_RS05205	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IN839_RS05210	COG0166	Belongs to the GPI family
IN839_RS05320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IN839_RS05350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IN839_RS05355	COG0315	cyclic pyranopterin monophosphate synthase activity
IN839_RS05355	COG0521	Mo-molybdopterin cofactor biosynthetic process
IN839_RS05390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IN839_RS05395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IN839_RS05430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IN839_RS05435	COG1104	cysteine desulfurase activity
IN839_RS05580	COG2235	arginine
IN839_RS05595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IN839_RS05610	COG1252	NADH dehydrogenase
IN839_RS05620	COG0084	hydrolase, TatD family'
IN839_RS05625	COG3583	domain protein
IN839_RS05640	COG2815	serine threonine protein kinase
IN839_RS05640	COG0515	serine threonine protein kinase
IN839_RS05660	COG2409	Drug exporters of the RND superfamily
IN839_RS05665	COG1846	Transcriptional regulator
IN839_RS05665	COG0456	acetyltransferase
IN839_RS05670	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IN839_RS05675	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS05690	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IN839_RS05725	COG1309	transcriptional regulator
IN839_RS05770	COG3956	TIGRFAM MazG family protein
IN839_RS05785	COG2837	iron assimilation
IN839_RS05790	COG2822	iron ion transport
IN839_RS05825	COG0596	Alpha beta hydrolase
IN839_RS05850	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS05860	COG0427	acetyl-CoA hydrolase
IN839_RS05910	COG1846	Transcriptional regulator
IN839_RS05925	COG1024	Enoyl-CoA hydratase
IN839_RS05950	COG0183	Belongs to the thiolase family
IN839_RS05955	COG2755	lipolytic protein G-D-S-L family
IN839_RS05960	COG0657	acetylesterase activity
IN839_RS05970	COG1714	RDD family
IN839_RS05985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IN839_RS06005	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IN839_RS06015	COG1331	Highly conserved protein containing a thioredoxin domain
IN839_RS06020	COG3631	Ketosteroid isomerase-related protein
IN839_RS06035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IN839_RS06040	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS06045	COG2124	cytochrome p450
IN839_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS06105	COG2272	Belongs to the type-B carboxylesterase lipase family
IN839_RS06115	COG1174	glycine betaine transport
IN839_RS06125	COG1174	glycine betaine transport
IN839_RS06170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IN839_RS06180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IN839_RS06185	COG0726	polysaccharide deacetylase
IN839_RS06255	COG1570	exodeoxyribonuclease VII activity
IN839_RS06265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IN839_RS06280	COG1966	Carbon starvation protein
IN839_RS06305	COG3189	MarR family transcriptional regulator
IN839_RS06310	COG0012	GTP binding
IN839_RS06335	COG2132	Multicopper oxidase
IN839_RS06345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IN839_RS06355	COG0488	(ABC) transporter
IN839_RS06410	COG2409	Drug exporters of the RND superfamily
IN839_RS06445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IN839_RS06465	COG1716	ATPase activity
IN839_RS06495	COG1051	belongs to the nudix hydrolase family
IN839_RS06520	COG1217	gtp-binding protein TYPA
IN839_RS06530	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IN839_RS06535	COG1609	Transcriptional regulator
IN839_RS06535	COG2207	Transcriptional regulator
IN839_RS06595	COG1902	pentaerythritol trinitrate reductase activity
IN839_RS06595	COG0446	pyridine nucleotide-disulphide oxidoreductase
IN839_RS06605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IN839_RS06615	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IN839_RS06620	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS06625	COG0506	proline dehydrogenase activity
IN839_RS06630	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS06655	COG2207	Transcriptional regulator
IN839_RS06670	COG1611	Belongs to the LOG family
IN839_RS06675	COG1611	Belongs to the LOG family
IN839_RS06680	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS06690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IN839_RS06700	COG0463	Glycosyl transferase, family 2
IN839_RS06715	COG0519	Catalyzes the synthesis of GMP from XMP
IN839_RS06725	COG0297	glycogen (starch) synthase activity
IN839_RS06750	COG3559	Exporter of polyketide antibiotics
IN839_RS06755	COG1131	(ABC) transporter
IN839_RS06760	COG1309	transcriptional regulator
IN839_RS06770	COG1595	DNA-templated transcription, initiation
IN839_RS06775	COG5662	AntiSigma factor
IN839_RS06780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IN839_RS06850	COG0598	Magnesium transport protein CorA
IN839_RS06855	COG1309	transcriptional regulator
IN839_RS06875	COG2095	MarC family integral membrane protein
IN839_RS06890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN839_RS06895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN839_RS06915	COG3835	regulator
IN839_RS06920	COG1073	alpha beta
IN839_RS06925	COG0567	Dehydrogenase, E1 component
IN839_RS06925	COG0508	dehydrogenase complex catalyzes the overall conversion of
IN839_RS06935	COG2814	Major facilitator Superfamily
IN839_RS06995	COG0277	FAD linked oxidase domain protein
IN839_RS07000	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS07015	COG0668	transmembrane transport
IN839_RS07105	COG2814	Major facilitator Superfamily
IN839_RS07135	COG0019	diaminopimelate decarboxylase activity
IN839_RS07140	COG0460	homoserine dehydrogenase
IN839_RS07145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IN839_RS07180	COG2890	protein-(glutamine-N5) methyltransferase activity
IN839_RS07190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IN839_RS07200	COG0356	it plays a direct role in the translocation of protons across the membrane
IN839_RS07205	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IN839_RS07230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IN839_RS07290	COG0346	lactoylglutathione lyase activity
IN839_RS07295	COG0183	Belongs to the thiolase family
IN839_RS07300	COG2409	Drug exporters of the RND superfamily
IN839_RS07315	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IN839_RS07320	COG0366	Alpha amylase catalytic
IN839_RS07325	COG0058	SHG alpha-glucan phosphorylase activity
IN839_RS07340	COG1335	isochorismatase
IN839_RS07350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IN839_RS07365	COG3191	aminopeptidase activity
IN839_RS07410	COG0604	alcohol dehydrogenase
IN839_RS07430	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS07445	COG0419	ATPase involved in DNA repair
IN839_RS07450	COG1024	Enoyl-CoA hydratase
IN839_RS07460	COG0243	molybdopterin cofactor binding
IN839_RS07475	COG2188	Transcriptional regulator
IN839_RS07530	COG0596	Alpha beta hydrolase
IN839_RS07535	COG3757	hydrolase, family 25
IN839_RS07550	COG1051	belongs to the nudix hydrolase family
IN839_RS07570	COG1309	transcriptional regulator
IN839_RS07585	COG4585	Histidine kinase
IN839_RS07590	COG2197	response regulator
IN839_RS07600	COG2239	Acts as a magnesium transporter
IN839_RS07610	COG0300	oxidoreductase activity
IN839_RS07620	COG0656	L-ascorbic acid biosynthetic process
IN839_RS07635	COG1376	ErfK ybiS ycfS ynhG family protein
IN839_RS07650	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IN839_RS07655	COG0433	COG0433 Predicted ATPase
IN839_RS07670	COG0300	oxidoreductase activity
IN839_RS07685	COG1301	dicarboxylic acid transport
IN839_RS07695	COG0531	amino acid
IN839_RS07715	COG4424	Sulfotransferase
IN839_RS07720	COG3119	arylsulfatase activity
IN839_RS07755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IN839_RS07755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IN839_RS07795	COG2902	Dehydrogenase
IN839_RS07800	COG0824	Thioesterase
IN839_RS07815	COG0366	Alpha amylase catalytic
IN839_RS07850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IN839_RS07870	COG1309	transcriptional regulator
IN839_RS07885	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IN839_RS07915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IN839_RS08000	COG0740	serine-type endopeptidase activity
IN839_RS08005	COG0740	serine-type endopeptidase activity
IN839_RS08055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IN839_RS08065	COG0674	pyruvate-flavodoxin oxidoreductase activity
IN839_RS08065	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IN839_RS08070	COG1013	pyruvate-flavodoxin oxidoreductase activity
IN839_RS08080	COG1388	LysM domain
IN839_RS08110	COG0525	valine-tRNA ligase activity
IN839_RS08115	COG0285	dihydrofolate synthase activity
IN839_RS08130	COG1530	ribonuclease E activity
IN839_RS08130	COG1530	ribonuclease E activity
IN839_RS08160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IN839_RS08180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN839_RS08185	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IN839_RS08190	COG0542	response to heat
IN839_RS08200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IN839_RS08210	COG0406	alpha-ribazole phosphatase activity
IN839_RS08215	COG2755	lipolytic protein G-D-S-L family
IN839_RS08235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN839_RS08270	COG2308	Evidence 4 Homologs of previously reported genes of
IN839_RS08280	COG1305	Transglutaminase-like
IN839_RS08310	COG3387	PFAM Glycoside hydrolase 15-related
IN839_RS08325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN839_RS08360	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IN839_RS08365	COG4208	sulfate ABC transporter
IN839_RS08425	COG0484	heat shock protein binding
IN839_RS08475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IN839_RS08505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IN839_RS08520	COG0076	glutamate decarboxylase activity
IN839_RS08555	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS08560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN839_RS08605	COG0423	glycine-tRNA ligase activity
IN839_RS08610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IN839_RS08615	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IN839_RS08635	COG0358	DNA primase activity
IN839_RS08700	COG0745	RESPONSE REGULATOR receiver
IN839_RS08705	COG5002	protein histidine kinase activity
IN839_RS09110	COG3179	chitinase
IN839_RS09305	COG0488	(ABC) transporter
IN839_RS09330	COG1960	acyl-CoA dehydrogenase activity
IN839_RS09335	COG1335	isochorismatase
IN839_RS09345	COG0058	SHG alpha-glucan phosphorylase activity
IN839_RS09385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN839_RS09390	COG1960	acyl-CoA dehydrogenase activity
IN839_RS09395	COG0183	Belongs to the thiolase family
IN839_RS09415	COG1228	amidohydrolase
IN839_RS09445	COG0604	alcohol dehydrogenase
IN839_RS09445	COG3321	synthase
IN839_RS09445	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS09465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IN839_RS09495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IN839_RS09525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN839_RS09570	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
IN839_RS09575	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IN839_RS09635	COG0714	Associated with various cellular activities
IN839_RS09660	COG0557	exoribonuclease II activity
IN839_RS09670	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS09695	COG0174	glutamine synthetase
IN839_RS09700	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IN839_RS09730	COG2205	protein histidine kinase activity
IN839_RS09760	COG0174	glutamine synthetase
IN839_RS09770	COG0477	Major facilitator Superfamily
IN839_RS09780	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IN839_RS09800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IN839_RS09805	COG0321	lipoyl(octanoyl) transferase activity
IN839_RS09820	COG1872	DUF167
IN839_RS09840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IN839_RS09850	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IN839_RS09855	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IN839_RS09885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN839_RS09930	COG2010	Cytochrome c
IN839_RS09935	COG1845	cytochrome c oxidase, subunit III
IN839_RS09940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IN839_RS09975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IN839_RS10000	COG0003	Pfam Anion-transporting ATPase
IN839_RS10010	COG0204	Acyl-transferase
IN839_RS10015	COG5650	phosphatidylinositol metabolic process
IN839_RS10025	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IN839_RS10050	COG0142	geranyltranstransferase activity
IN839_RS10090	COG0768	penicillin binding
IN839_RS10110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IN839_RS10120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IN839_RS10135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IN839_RS10160	COG0640	Transcriptional regulator
IN839_RS10215	COG0154	amidase activity
IN839_RS10225	COG2957	Belongs to the agmatine deiminase family
IN839_RS10235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IN839_RS10245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IN839_RS10255	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS10285	COG2814	Major facilitator Superfamily
IN839_RS10360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS10365	COG2030	dehydratase
IN839_RS10385	COG1024	Enoyl-CoA hydratase
IN839_RS10400	COG1309	transcriptional regulator
IN839_RS10420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IN839_RS10465	COG2072	flavoprotein involved in K transport
IN839_RS10480	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS10485	COG1960	acyl-CoA dehydrogenase activity
IN839_RS10505	COG1960	acyl-CoA dehydrogenase activity
IN839_RS10530	COG3621	Patatin-like phospholipase
IN839_RS10590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IN839_RS10620	COG1968	undecaprenyl-diphosphatase activity
IN839_RS10655	COG1218	3'(2'),5'-bisphosphate nucleotidase
IN839_RS10665	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS10690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IN839_RS10700	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IN839_RS10700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IN839_RS10715	COG2860	membrane
IN839_RS10725	COG1410	methionine synthase
IN839_RS10725	COG0646	methionine synthase
IN839_RS10730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IN839_RS10740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IN839_RS10775	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IN839_RS10780	COG1034	ATP synthesis coupled electron transport
IN839_RS10785	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IN839_RS10790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IN839_RS10870	COG0513	Belongs to the DEAD box helicase family
IN839_RS10905	COG0028	Belongs to the TPP enzyme family
IN839_RS10920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IN839_RS10925	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IN839_RS10930	COG4122	O-methyltransferase activity
IN839_RS10960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IN839_RS10965	COG4521	taurine ABC transporter
IN839_RS10970	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IN839_RS11005	COG2378	regulation of single-species biofilm formation
IN839_RS11010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IN839_RS11045	COG0300	oxidoreductase activity
IN839_RS11100	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IN839_RS11110	COG0463	Glycosyl transferase, family 2
IN839_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS11140	COG0604	alcohol dehydrogenase
IN839_RS11140	COG3321	synthase
IN839_RS11160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IN839_RS11170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IN839_RS11175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS11195	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IN839_RS11205	COG1404	Belongs to the peptidase S8 family
IN839_RS11220	COG4842	Belongs to the WXG100 family
IN839_RS11250	COG0464	growth
IN839_RS11270	COG0583	DNA-binding transcription factor activity
IN839_RS11300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IN839_RS11305	COG1169	isochorismate synthase
IN839_RS11310	COG0789	Transcriptional regulator
IN839_RS11315	COG1021	2,3-dihydroxybenzoate-AMP ligase
IN839_RS11345	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IN839_RS11370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IN839_RS11370	COG0300	oxidoreductase activity
IN839_RS11370	COG3321	synthase
IN839_RS11370	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS11370	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS11385	COG1132	(ABC) transporter
IN839_RS11390	COG1132	(ABC) transporter
IN839_RS11390	COG2375	cellular response to nickel ion
IN839_RS11395	COG0477	Major facilitator Superfamily
IN839_RS11400	COG5285	phytanoyl-CoA dioxygenase
IN839_RS11410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IN839_RS11415	COG0456	acetyltransferase
IN839_RS11430	COG2837	iron assimilation
IN839_RS11440	COG2186	Transcriptional regulator
IN839_RS11445	COG2807	transmembrane transport
IN839_RS11455	COG2409	Drug exporters of the RND superfamily
IN839_RS11460	COG3629	intracellular signal transduction
IN839_RS11465	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS11505	COG0475	glutathione-regulated potassium exporter activity
IN839_RS11575	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IN839_RS11575	COG0237	dephospho-CoA kinase activity
IN839_RS11760	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IN839_RS11765	COG0072	phenylalanine-tRNA ligase activity
IN839_RS11765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IN839_RS11775	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IN839_RS11780	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IN839_RS11785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IN839_RS11790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IN839_RS11795	COG1438	arginine binding
IN839_RS11800	COG0137	argininosuccinate synthase activity
IN839_RS11840	COG2835	tetraacyldisaccharide 4'-kinase activity
IN839_RS11845	COG1309	transcriptional regulator
IN839_RS11850	COG2094	Belongs to the DNA glycosylase MPG family
IN839_RS11875	COG0647	UMP catabolic process
IN839_RS11890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IN839_RS11910	COG0504	CTP synthase activity
IN839_RS11915	COG0494	nUDIX hydrolase
IN839_RS11935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IN839_RS11950	COG1160	GTP binding
IN839_RS11960	COG1403	HNH endonuclease
IN839_RS12040	COG3976	FMN-binding domain protein
IN839_RS12040	COG1053	succinate dehydrogenase
IN839_RS12070	COG1960	acyl-CoA dehydrogenase activity
IN839_RS12130	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IN839_RS12130	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IN839_RS12145	COG1253	flavin adenine dinucleotide binding
IN839_RS12150	COG1253	flavin adenine dinucleotide binding
IN839_RS12160	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IN839_RS12215	COG0832	Belongs to the urease beta subunit family
IN839_RS12225	COG0830	nickel cation binding
IN839_RS12240	COG1252	NADH dehydrogenase
IN839_RS12250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS12285	COG0243	molybdopterin cofactor binding
IN839_RS12295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IN839_RS12310	COG1546	Belongs to the CinA family
IN839_RS12310	COG1058	Belongs to the CinA family
IN839_RS12320	COG4977	sequence-specific DNA binding
IN839_RS12325	COG1741	Belongs to the pirin family
IN839_RS12350	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IN839_RS12375	COG0277	FAD linked oxidase domain protein
IN839_RS12385	COG1309	transcriptional regulator
IN839_RS12400	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IN839_RS12405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IN839_RS12410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IN839_RS12435	COG4290	ribonuclease
IN839_RS12465	COG3883	PFAM NLP P60 protein
IN839_RS12465	COG0791	NLP P60 protein
IN839_RS12500	COG0477	Major facilitator Superfamily
IN839_RS12520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IN839_RS12525	COG0067	glutamate synthase
IN839_RS12525	COG0069	glutamate synthase activity
IN839_RS12525	COG0070	glutamate synthase
IN839_RS12550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IN839_RS12565	COG1960	acyl-CoA dehydrogenase activity
IN839_RS12580	COG0443	Heat shock 70 kDa protein
IN839_RS12585	COG0596	Alpha beta hydrolase
IN839_RS12605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IN839_RS12615	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IN839_RS12640	COG2890	protein-(glutamine-N5) methyltransferase activity
IN839_RS12710	COG1982	Orn Lys Arg decarboxylase major
IN839_RS12770	COG0028	Belongs to the TPP enzyme family
IN839_RS12780	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS12800	COG1309	transcriptional regulator
IN839_RS12805	COG2957	Belongs to the agmatine deiminase family
IN839_RS12810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN839_RS12825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IN839_RS12875	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IN839_RS12890	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IN839_RS12910	COG0640	Transcriptional regulator
IN839_RS12920	COG0798	PFAM Bile acid sodium symporter
IN839_RS12925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IN839_RS12930	COG0390	transport system, permease component
IN839_RS12950	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS12955	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN839_RS13010	COG0745	RESPONSE REGULATOR receiver
IN839_RS13015	COG2205	protein histidine kinase activity
IN839_RS13030	COG1917	Cupin 2, conserved barrel domain protein
IN839_RS13035	COG3707	response regulator
IN839_RS13075	COG3467	pyridoxamine 5'-phosphate
IN839_RS13080	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
IN839_RS13100	COG0640	Transcriptional regulator
IN839_RS13120	COG1309	transcriptional regulator
IN839_RS13125	COG2072	flavoprotein involved in K transport
IN839_RS13135	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS13140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IN839_RS13145	COG0561	phosphatase activity
IN839_RS13150	COG0673	inositol 2-dehydrogenase activity
IN839_RS13155	COG0738	Major facilitator superfamily
IN839_RS13240	COG1271	oxidase subunit
IN839_RS13245	COG1294	oxidase, subunit
IN839_RS13250	COG4988	ABC transporter
IN839_RS13255	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IN839_RS13280	COG1946	Acyl-CoA thioesterase
IN839_RS13325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IN839_RS13330	COG1846	Transcriptional regulator
IN839_RS13355	COG2072	flavoprotein involved in K transport
IN839_RS13360	COG0657	acetylesterase activity
IN839_RS13410	COG0483	inositol monophosphate 1-phosphatase activity
IN839_RS13420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IN839_RS13425	COG0131	Imidazoleglycerol-phosphate dehydratase
IN839_RS13430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IN839_RS13455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IN839_RS13470	COG1309	transcriptional regulator
IN839_RS13485	COG0583	DNA-binding transcription factor activity
IN839_RS13490	COG0579	oxidoreductase
IN839_RS13530	COG2755	lipolytic protein G-D-S-L family
IN839_RS13530	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IN839_RS13585	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IN839_RS13605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IN839_RS13610	COG2814	Major facilitator Superfamily
IN839_RS13615	COG0583	DNA-binding transcription factor activity
IN839_RS13665	COG2239	Acts as a magnesium transporter
IN839_RS13695	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IN839_RS13705	COG2304	oxidoreductase activity
IN839_RS13715	COG0714	Associated with various cellular activities
IN839_RS13725	COG0791	NLP P60 protein
IN839_RS13725	COG3883	PFAM NLP P60 protein
IN839_RS13735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IN839_RS13740	COG1309	transcriptional regulator
IN839_RS13765	COG0488	(ABC) transporter
IN839_RS13780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IN839_RS13795	COG0456	acetyltransferase
IN839_RS13805	COG2151	metal-sulfur cluster biosynthetic enzyme
IN839_RS13820	COG0396	ATPase activity
IN839_RS13845	COG1131	(ABC) transporter
IN839_RS13885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IN839_RS13905	COG0583	DNA-binding transcription factor activity
IN839_RS13910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN839_RS13980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IN839_RS14040	COG0531	amino acid
IN839_RS14095	COG2011	ABC-type metal ion transport system permease component
IN839_RS14100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IN839_RS14120	COG0477	Major facilitator Superfamily
IN839_RS14155	COG0657	acetylesterase activity
IN839_RS14160	COG1953	Uracil, thiamine, allantoin
IN839_RS14170	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IN839_RS14175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN839_RS14185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IN839_RS14195	COG1758	RNA polymerase activity
IN839_RS14215	COG0284	orotidine-5'-phosphate decarboxylase activity
IN839_RS14220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IN839_RS14225	COG0505	Belongs to the CarA family
IN839_RS14245	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IN839_RS14265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IN839_RS14275	COG0006	proline dipeptidase activity
IN839_RS14290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IN839_RS14295	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IN839_RS14310	COG4106	trans-aconitate 2-methyltransferase activity
IN839_RS14325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IN839_RS14340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IN839_RS14390	COG0701	Predicted permease
IN839_RS14415	COG2272	Belongs to the type-B carboxylesterase lipase family
IN839_RS14455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IN839_RS14465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IN839_RS14475	COG0747	negative chemotaxis
IN839_RS14480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IN839_RS14495	COG2255	four-way junction helicase activity
IN839_RS14505	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IN839_RS14540	COG1946	Acyl-CoA thioesterase
IN839_RS14545	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IN839_RS14555	COG0438	transferase activity, transferring glycosyl groups
IN839_RS14595	COG4762	Protein conserved in bacteria
IN839_RS14650	COG1309	transcriptional regulator
IN839_RS14675	COG3878	Protein conserved in bacteria
IN839_RS14715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN839_RS14730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IN839_RS14730	COG2080	2 iron, 2 sulfur cluster binding
IN839_RS14745	COG0402	S-adenosylhomocysteine deaminase activity
IN839_RS14765	COG2233	PERMEase
IN839_RS14785	COG1953	Uracil, thiamine, allantoin
IN839_RS14795	COG1301	dicarboxylic acid transport
IN839_RS14805	COG4266	Belongs to the allantoicase family
IN839_RS14835	COG2267	carboxylic ester hydrolase activity
IN839_RS14840	COG1960	acyl-CoA dehydrogenase activity
IN839_RS14845	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS14860	COG0183	Belongs to the thiolase family
IN839_RS14890	COG0477	Major facilitator Superfamily
IN839_RS14945	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN839_RS14955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IN839_RS14995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IN839_RS15020	COG3253	May function as heme-dependent peroxidase
IN839_RS15025	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IN839_RS15030	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IN839_RS15040	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IN839_RS15055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IN839_RS15060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IN839_RS15065	COG0531	amino acid
IN839_RS15070	COG0569	domain protein
IN839_RS15100	COG0702	epimerase
IN839_RS15115	COG0756	dUTP diphosphatase activity
IN839_RS15160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IN839_RS15210	COG3220	belongs to the UPF0276 family
IN839_RS15285	COG1388	LysM domain
IN839_RS15300	COG1960	acyl-CoA dehydrogenase activity
IN839_RS15310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IN839_RS15330	COG1196	nuclear chromosome segregation
IN839_RS15350	COG1126	abc transporter atp-binding protein
IN839_RS15355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN839_RS15360	COG0765	amino acid transport
IN839_RS15365	COG0765	amino acid transport
IN839_RS15415	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
IN839_RS15420	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
IN839_RS15435	COG1842	Phage shock protein A
IN839_RS15440	COG1396	sequence-specific DNA binding
IN839_RS15450	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS15460	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IN839_RS15515	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IN839_RS15520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IN839_RS15535	COG3214	Protein conserved in bacteria
IN839_RS15575	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IN839_RS15585	COG0659	secondary active sulfate transmembrane transporter activity
IN839_RS15595	COG0686	Belongs to the AlaDH PNT family
IN839_RS15610	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS15680	COG2977	Belongs to the P-Pant transferase superfamily
IN839_RS15685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IN839_RS15705	COG1960	acyl-CoA dehydrogenase activity
IN839_RS15710	COG1960	acyl-CoA dehydrogenase activity
IN839_RS15715	COG1024	Enoyl-CoA hydratase
IN839_RS15740	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IN839_RS15765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN839_RS15765	COG1017	nitric oxide dioxygenase activity
IN839_RS15770	COG1959	2 iron, 2 sulfur cluster binding
IN839_RS15815	COG1648	precorrin-2 dehydrogenase activity
IN839_RS15815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IN839_RS15840	COG0604	alcohol dehydrogenase
IN839_RS15840	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS15840	COG3321	synthase
IN839_RS15900	COG0579	oxidoreductase
IN839_RS15920	COG1492	cobalamin metabolic process
IN839_RS15930	COG1376	ErfK ybiS ycfS ynhG family protein
IN839_RS15955	COG0750	zinc metalloprotease
IN839_RS15980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IN839_RS16045	COG0528	UMP kinase activity
IN839_RS16050	COG3973	AAA domain
IN839_RS16065	COG2723	6-phospho-beta-galactosidase activity
IN839_RS16100	COG1309	transcriptional regulator
IN839_RS16140	COG0583	DNA-binding transcription factor activity
IN839_RS16165	COG0792	nuclease activity
IN839_RS16225	COG0336	Belongs to the RNA methyltransferase TrmD family
IN839_RS16265	COG1686	Belongs to the peptidase S11 family
IN839_RS16285	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IN839_RS16305	COG1304	FMN binding
IN839_RS16330	COG1254	Belongs to the acylphosphatase family
IN839_RS16355	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IN839_RS16360	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IN839_RS16380	COG0571	ribonuclease III activity
IN839_RS16390	COG3599	regulation of cell shape
IN839_RS16430	COG0742	ribosomal rna small subunit methyltransferase
IN839_RS16435	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IN839_RS16450	COG0657	acetylesterase activity
IN839_RS16455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS16475	COG2124	cytochrome p450
IN839_RS16490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IN839_RS16495	COG1461	Dihydroxyacetone kinase
IN839_RS16505	COG1024	Enoyl-CoA hydratase
IN839_RS16530	COG1181	Belongs to the D-alanine--D-alanine ligase family
IN839_RS16535	COG0626	cystathionine gamma-synthase activity
IN839_RS16540	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IN839_RS16605	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN839_RS16620	COG2271	Major facilitator Superfamily
IN839_RS16655	COG0583	DNA-binding transcription factor activity
IN839_RS16665	COG0778	Nitroreductase
IN839_RS16680	COG1309	transcriptional regulator
IN839_RS16685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN839_RS16690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN839_RS16695	COG2124	cytochrome p450
IN839_RS16725	COG0440	acetolactate synthase activity
IN839_RS16740	COG1748	Saccharopine dehydrogenase
IN839_RS16745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IN839_RS16765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN839_RS16785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IN839_RS16795	COG2272	Belongs to the type-B carboxylesterase lipase family
IN839_RS16810	COG0745	RESPONSE REGULATOR receiver
IN839_RS16815	COG2205	protein histidine kinase activity
IN839_RS16840	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IN839_RS16870	COG1024	Enoyl-CoA hydratase
IN839_RS16875	COG0778	Nitroreductase
IN839_RS16885	COG2252	PERMEase
IN839_RS16925	COG2197	response regulator
IN839_RS16930	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IN839_RS16940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IN839_RS16965	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IN839_RS16980	COG1309	transcriptional regulator
IN839_RS17010	COG0110	maltose O-acetyltransferase activity
IN839_RS17015	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IN839_RS17040	COG1119	ATPase activity
IN839_RS17050	COG2364	Membrane
IN839_RS17055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IN839_RS17070	COG4607	ABC-type enterochelin transport system periplasmic component
IN839_RS17120	COG1064	alcohol dehydrogenase
IN839_RS17140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IN839_RS17145	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS17205	COG0477	Major facilitator Superfamily
IN839_RS17225	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS17255	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS17280	COG1335	isochorismatase
IN839_RS17290	COG2855	membrane
IN839_RS17300	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS17315	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS17325	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS17330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IN839_RS17390	COG2272	Belongs to the type-B carboxylesterase lipase family
IN839_RS17405	COG0183	Belongs to the thiolase family
IN839_RS17440	COG1309	transcriptional regulator
IN839_RS17470	COG0789	Transcriptional regulator
IN839_RS17480	COG0028	Belongs to the TPP enzyme family
IN839_RS17505	COG2177	Part of the ABC transporter FtsEX involved in
IN839_RS17510	COG2884	Cell division ATP-binding protein ftsE
IN839_RS17520	COG0668	transmembrane transport
IN839_RS17560	COG0483	inositol monophosphate 1-phosphatase activity
IN839_RS17565	COG1960	acyl-CoA dehydrogenase activity
IN839_RS17570	COG1960	acyl-CoA dehydrogenase activity
IN839_RS17585	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS17595	COG0542	response to heat
IN839_RS17640	COG3480	Lon protease (S16) C-terminal proteolytic domain
IN839_RS17645	COG3011	Protein conserved in bacteria
IN839_RS17660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN839_RS17665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN839_RS17675	COG0300	oxidoreductase activity
IN839_RS17680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN839_RS17715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IN839_RS17715	COG0475	glutathione-regulated potassium exporter activity
IN839_RS17730	COG0596	Alpha beta hydrolase
IN839_RS17745	COG0745	RESPONSE REGULATOR receiver
IN839_RS17755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IN839_RS17755	COG2146	nitrite reductase [NAD(P)H] activity
IN839_RS17760	COG2223	nitrite transmembrane transporter activity
IN839_RS17800	COG0513	Belongs to the DEAD box helicase family
IN839_RS17815	COG0406	alpha-ribazole phosphatase activity
IN839_RS17835	COG1597	lipid kinase activity
IN839_RS17850	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IN839_RS17860	COG1595	DNA-templated transcription, initiation
IN839_RS17865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IN839_RS17870	COG2135	peptidase activity
IN839_RS17875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IN839_RS17880	COG1162	GTPase activity
IN839_RS17915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IN839_RS18010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IN839_RS18015	COG0604	alcohol dehydrogenase
IN839_RS18015	COG3321	synthase
IN839_RS18020	COG0604	alcohol dehydrogenase
IN839_RS18020	COG3321	synthase
IN839_RS18025	COG1960	acyl-CoA dehydrogenase activity
IN839_RS18035	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS18040	COG0653	protein targeting
IN839_RS18050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IN839_RS18055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IN839_RS18065	COG1309	transcriptional regulator
IN839_RS18080	COG5401	PFAM Sporulation and spore germination
IN839_RS18085	COG5002	protein histidine kinase activity
IN839_RS18095	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS18100	COG1285	pathogenesis
IN839_RS18130	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IN839_RS18135	COG0531	amino acid
IN839_RS18145	COG1482	cell wall glycoprotein biosynthetic process
IN839_RS18175	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IN839_RS18180	COG0778	Nitroreductase
IN839_RS18180	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IN839_RS18195	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IN839_RS18210	COG1316	TRANSCRIPTIONal
IN839_RS18230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IN839_RS18240	COG2175	clavaminate synthase activity
IN839_RS18265	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IN839_RS18265	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IN839_RS18275	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS18290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IN839_RS18310	COG3265	gluconokinase activity
IN839_RS18315	COG1960	acyl-CoA dehydrogenase activity
IN839_RS18330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS18350	COG4770	biotin carboxylase activity
IN839_RS18360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IN839_RS18380	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS18385	COG1309	transcriptional regulator
IN839_RS18390	COG1201	RNA secondary structure unwinding
IN839_RS18405	COG0564	pseudouridine synthase activity
IN839_RS18425	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IN839_RS18425	COG1473	amidohydrolase
IN839_RS18440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IN839_RS18455	COG3883	PFAM NLP P60 protein
IN839_RS18455	COG0791	NLP P60 protein
IN839_RS18500	COG2009	succinate dehydrogenase
IN839_RS18515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IN839_RS18520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IN839_RS18525	COG1595	DNA-templated transcription, initiation
IN839_RS18540	COG1686	Belongs to the peptidase S11 family
IN839_RS18555	COG0708	Exodeoxyribonuclease III
IN839_RS18615	COG1733	regulation of RNA biosynthetic process
IN839_RS18620	COG2910	NAD(P)H-binding
IN839_RS18625	COG1716	ATPase activity
IN839_RS18625	COG0842	Transport permease protein
IN839_RS18625	COG1131	(ABC) transporter
IN839_RS18630	COG1357	PFAM Pentapeptide repeats (8 copies)
IN839_RS18645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IN839_RS18650	COG0587	DNA-directed DNA polymerase activity
IN839_RS18655	COG1073	alpha beta
IN839_RS18660	COG1309	transcriptional regulator
IN839_RS18725	COG0519	Catalyzes the synthesis of GMP from XMP
IN839_RS18725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IN839_RS18735	COG0516	GMP reductase activity
IN839_RS18795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IN839_RS18810	COG0456	acetyltransferase
IN839_RS18830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IN839_RS18835	COG0076	glutamate decarboxylase activity
IN839_RS18845	COG2267	carboxylic ester hydrolase activity
IN839_RS18850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IN839_RS18875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS18885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IN839_RS18890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IN839_RS18925	COG1404	Belongs to the peptidase S8 family
IN839_RS18955	COG2267	carboxylic ester hydrolase activity
IN839_RS19010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IN839_RS19015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN839_RS19025	COG2268	Band 7 protein
IN839_RS19035	COG1088	dTDP-glucose 4,6-dehydratase activity
IN839_RS19040	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IN839_RS19085	COG0616	signal peptide processing
IN839_RS19100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS19120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IN839_RS19130	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IN839_RS19140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IN839_RS19155	COG2272	Belongs to the type-B carboxylesterase lipase family
IN839_RS19180	COG0477	Major facilitator Superfamily
IN839_RS19195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IN839_RS19235	COG0088	Forms part of the polypeptide exit tunnel
IN839_RS19240	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IN839_RS19245	COG0051	transcription antitermination factor activity, RNA binding
IN839_RS19280	COG0531	amino acid
IN839_RS19310	COG0535	radical SAM domain protein
IN839_RS19335	COG1834	amidinotransferase
IN839_RS19340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IN839_RS19345	COG0531	amino acid
IN839_RS19390	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IN839_RS19395	COG1309	transcriptional regulator
IN839_RS19420	COG1024	Enoyl-CoA hydratase
IN839_RS19435	COG1960	acyl-CoA dehydrogenase activity
IN839_RS19465	COG1113	amino acid transport
IN839_RS19480	COG0085	RNA polymerase activity
IN839_RS19485	COG0243	molybdopterin cofactor binding
IN839_RS19540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IN839_RS19555	COG0277	FAD linked oxidase domain protein
IN839_RS19575	COG4941	Belongs to the sigma-70 factor family
IN839_RS19610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IN839_RS19650	COG0783	Belongs to the Dps family
IN839_RS19655	COG0693	protein deglycase activity
IN839_RS19700	COG1404	Belongs to the peptidase S8 family
IN839_RS19720	COG1280	lysine exporter protein (LysE YggA)
IN839_RS19790	COG0501	Belongs to the peptidase M48B family
IN839_RS19795	COG0142	geranyltranstransferase activity
IN839_RS19800	COG0644	oxidoreductase
IN839_RS19810	COG0438	transferase activity, transferring glycosyl groups
IN839_RS19830	COG4948	Mandelate Racemase Muconate Lactonizing
IN839_RS19855	COG3706	GGDEF domain
IN839_RS19870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IN839_RS19880	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IN839_RS19885	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS19890	COG4221	oxidoreductase activity
IN839_RS19940	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IN839_RS19945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IN839_RS19985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IN839_RS20030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IN839_RS20035	COG1333	cytochrome c biogenesis protein
IN839_RS20040	COG0785	Cytochrome C biogenesis protein
IN839_RS20050	COG0406	alpha-ribazole phosphatase activity
IN839_RS20070	COG3590	peptidase
IN839_RS20120	COG1587	Uroporphyrinogen-III synthase
IN839_RS20120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IN839_RS20145	COG2030	dehydratase
IN839_RS20170	COG2070	2-Nitropropane dioxygenase
IN839_RS20195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IN839_RS20200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN839_RS20305	COG1309	transcriptional regulator
IN839_RS20315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN839_RS20365	COG2072	flavoprotein involved in K transport
IN839_RS20380	COG2072	flavoprotein involved in K transport
IN839_RS20385	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS20390	COG0657	acetylesterase activity
IN839_RS20395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IN839_RS20405	COG0745	RESPONSE REGULATOR receiver
IN839_RS20410	COG5002	protein histidine kinase activity
IN839_RS20420	COG2072	flavoprotein involved in K transport
IN839_RS20435	COG0300	oxidoreductase activity
IN839_RS20490	COG2814	Major facilitator Superfamily
IN839_RS20495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IN839_RS20590	COG2733	membrane
IN839_RS20600	COG2326	polyphosphate kinase activity
IN839_RS20605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IN839_RS20640	COG2224	Isocitrate lyase
IN839_RS20680	COG2226	methyltransferase
IN839_RS20730	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IN839_RS20765	COG0667	Aldo Keto reductase
IN839_RS20790	COG4552	Acetyltransferase involved in intracellular survival and related
IN839_RS20795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS20820	COG1505	serine-type exopeptidase activity
IN839_RS20840	COG1073	alpha beta
IN839_RS20845	COG2326	polyphosphate kinase activity
IN839_RS20860	COG2223	nitrite transmembrane transporter activity
IN839_RS20865	COG0640	Transcriptional regulator
IN839_RS20895	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IN839_RS20915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IN839_RS20940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN839_RS20945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN839_RS20950	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS20960	COG1960	acyl-CoA dehydrogenase activity
IN839_RS20965	COG1960	acyl-CoA dehydrogenase activity
IN839_RS20970	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS20980	COG2070	2-Nitropropane dioxygenase
IN839_RS20990	COG1024	Enoyl-CoA hydratase
IN839_RS20995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IN839_RS21000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS21035	COG4638	Rieske (2fe-2S)
IN839_RS21075	COG0175	sulfate reduction
IN839_RS21145	COG2814	Major facilitator Superfamily
IN839_RS21155	COG0351	phosphomethylpyrimidine kinase
IN839_RS21165	COG1252	NADH dehydrogenase
IN839_RS21175	COG1309	transcriptional regulator
IN839_RS21185	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS21220	COG0494	nUDIX hydrolase
IN839_RS21230	COG2234	aminopeptidase activity
IN839_RS21235	COG2234	aminopeptidase activity
IN839_RS21245	COG1131	(ABC) transporter
IN839_RS21250	COG2022	thiamine diphosphate biosynthetic process
IN839_RS21285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN839_RS21290	COG0515	serine threonine protein kinase
IN839_RS21295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IN839_RS21325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IN839_RS21330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS21335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS21340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS21350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN839_RS21355	COG1126	abc transporter atp-binding protein
IN839_RS21395	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IN839_RS21430	COG1994	Peptidase M50
IN839_RS21450	COG0586	Pfam SNARE associated Golgi protein
IN839_RS21480	COG4221	oxidoreductase activity
IN839_RS21500	COG0542	response to heat
IN839_RS21525	COG0789	Transcriptional regulator
IN839_RS21530	COG0484	heat shock protein binding
IN839_RS21535	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IN839_RS21605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IN839_RS21605	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IN839_RS21645	COG2181	nitrate reductase activity
IN839_RS21645	COG0247	lactate metabolic process
IN839_RS21655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IN839_RS21695	COG3345	alpha-galactosidase
IN839_RS21700	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IN839_RS21705	COG1305	Transglutaminase-like
IN839_RS21720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IN839_RS21790	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS21800	COG0454	-acetyltransferase
IN839_RS21855	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS21860	COG1960	acyl-CoA dehydrogenase activity
IN839_RS21875	COG3268	Saccharopine dehydrogenase
IN839_RS21880	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS21885	COG1793	dna ligase
IN839_RS21885	COG3285	dna ligase
IN839_RS21890	COG0494	nUDIX hydrolase
IN839_RS21900	COG2902	Dehydrogenase
IN839_RS21905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IN839_RS21920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN839_RS21940	COG1309	transcriptional regulator
IN839_RS21955	COG0778	Nitroreductase
IN839_RS21960	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN839_RS21985	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN839_RS21990	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS21995	COG1396	sequence-specific DNA binding
IN839_RS22000	COG1414	Transcriptional regulator
IN839_RS22015	COG2267	carboxylic ester hydrolase activity
IN839_RS22020	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IN839_RS22035	COG4638	Rieske (2fe-2S)
IN839_RS22040	COG0604	alcohol dehydrogenase
IN839_RS22040	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS22040	COG3321	synthase
IN839_RS22045	COG3384	dioxygenase
IN839_RS22050	COG3971	2-oxopent-4-enoate hydratase activity
IN839_RS22065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IN839_RS22070	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS22105	COG1309	transcriptional regulator
IN839_RS22130	COG1309	transcriptional regulator
IN839_RS22135	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IN839_RS22150	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IN839_RS22155	COG1984	allophanate hydrolase subunit 2
IN839_RS22220	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IN839_RS22225	COG1802	Transcriptional regulator
IN839_RS22255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IN839_RS22265	COG0473	3-isopropylmalate dehydrogenase activity
IN839_RS22280	COG1053	succinate dehydrogenase
IN839_RS22300	COG0640	Transcriptional regulator
IN839_RS22350	COG2318	DinB family
IN839_RS22355	COG1960	acyl-CoA dehydrogenase activity
IN839_RS22370	COG1660	Displays ATPase and GTPase activities
IN839_RS22380	COG0183	Belongs to the thiolase family
IN839_RS22385	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS22390	COG2030	dehydratase
IN839_RS22405	COG0659	secondary active sulfate transmembrane transporter activity
IN839_RS22410	COG1309	transcriptional regulator
IN839_RS22415	COG0861	Integral membrane protein TerC family
IN839_RS22440	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS22455	COG1472	Belongs to the glycosyl hydrolase 3 family
IN839_RS22460	COG4941	Belongs to the sigma-70 factor family
IN839_RS22525	COG4981	capsule polysaccharide biosynthetic process
IN839_RS22565	COG0438	transferase activity, transferring glycosyl groups
IN839_RS22610	COG1250	3-hydroxyacyl-CoA dehydrogenase
IN839_RS22655	COG2197	response regulator
IN839_RS22660	COG3850	Histidine kinase
IN839_RS22680	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IN839_RS22710	COG2409	Drug exporters of the RND superfamily
IN839_RS22755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN839_RS22765	COG2197	response regulator
IN839_RS22795	COG2353	YceI-like domain
IN839_RS22810	COG2409	Drug exporters of the RND superfamily
IN839_RS22825	COG4552	Acetyltransferase involved in intracellular survival and related
IN839_RS22830	COG1832	CoA-binding protein
IN839_RS22845	COG3590	peptidase
IN839_RS22850	COG1376	ErfK ybiS ycfS ynhG family protein
IN839_RS22855	COG1960	acyl-CoA dehydrogenase activity
IN839_RS22865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IN839_RS22875	COG1937	Protein conserved in bacteria
IN839_RS22900	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS22905	COG4122	O-methyltransferase activity
IN839_RS22920	COG2267	carboxylic ester hydrolase activity
IN839_RS22950	COG1704	LemA family
IN839_RS22960	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS23015	COG1024	Enoyl-CoA hydratase
IN839_RS23020	COG1802	Transcriptional regulator
IN839_RS23030	COG2267	carboxylic ester hydrolase activity
IN839_RS23035	COG1309	transcriptional regulator
IN839_RS23065	COG0435	Glutathione S-transferase
IN839_RS23105	COG1024	Enoyl-CoA hydratase
IN839_RS23115	COG2211	Major facilitator Superfamily
IN839_RS23120	COG2365	Tyrosine phosphatase family
IN839_RS23185	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS23190	COG1012	belongs to the aldehyde dehydrogenase family
IN839_RS23205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IN839_RS23210	COG1960	acyl-CoA dehydrogenase activity
IN839_RS23215	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IN839_RS23230	COG2226	methyltransferase
IN839_RS23245	COG3800	Transcriptional regulator
IN839_RS23245	COG1396	sequence-specific DNA binding
IN839_RS23255	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IN839_RS23295	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS23355	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IN839_RS23365	COG0129	dihydroxy-acid dehydratase activity
IN839_RS23385	COG2186	Transcriptional regulator
IN839_RS23415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IN839_RS23420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN839_RS23430	COG0723	plastoquinol--plastocyanin reductase activity
IN839_RS23450	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS23490	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS23505	COG0318	PFAM AMP-dependent synthetase and ligase
IN839_RS23510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IN839_RS23515	COG1136	(ABC) transporter
IN839_RS23525	COG1104	cysteine desulfurase activity
IN839_RS23585	COG1309	transcriptional regulator
IN839_RS23595	COG1819	glycosyl
IN839_RS23640	COG1819	glycosyl
IN839_RS23755	COG3263	regulation of cellular component size
IN839_RS23835	COG1595	DNA-templated transcription, initiation
IN839_RS23845	COG0783	Belongs to the Dps family
IN839_RS23890	COG1252	NADH dehydrogenase
IN839_RS23910	COG1937	Protein conserved in bacteria
IN839_RS23935	COG1403	HNH endonuclease
IN839_RS24010	COG2140	Oxalate decarboxylase
IN839_RS24035	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IN839_RS24055	COG1376	ErfK ybiS ycfS ynhG family protein
IN839_RS24075	COG2030	dehydratase
IN839_RS24080	COG0488	(ABC) transporter
IN839_RS24085	COG3757	hydrolase, family 25
IN839_RS24150	COG0583	DNA-binding transcription factor activity
IN839_RS24160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN839_RS24175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN839_RS24180	COG3757	hydrolase, family 25
IN839_RS24390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IN839_RS24420	COG0745	RESPONSE REGULATOR receiver
IN839_RS24425	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IN839_RS24485	COG0640	Transcriptional regulator
IN839_RS24490	COG0640	Transcriptional regulator
IN839_RS24495	COG0798	PFAM Bile acid sodium symporter
IN839_RS24500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IN839_RS24505	COG0446	pyridine nucleotide-disulphide oxidoreductase
IN839_RS24515	COG0717	Belongs to the dCTP deaminase family
IN839_RS24555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IN839_RS24580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IN839_RS24590	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IN839_RS24625	COG0454	-acetyltransferase
IN839_RS24670	COG0629	single-stranded DNA binding
IN839_RS24685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IN839_RS24715	COG1260	myo-inositol-1-phosphate synthase
IN839_RS24725	COG1113	amino acid transport
IN839_RS24740	COG1309	transcriptional regulator
IN839_RS24745	COG1028	Short-chain dehydrogenase reductase Sdr
IN839_RS24760	COG0508	dehydrogenase complex catalyzes the overall conversion of
IN839_RS24765	COG0022	dehydrogenase e1 component
IN839_RS24780	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IN839_RS24785	COG2311	Membrane
IN839_RS24850	COG0617	tRNA 3'-terminal CCA addition
IN839_RS24870	COG1595	DNA-templated transcription, initiation
IN839_RS24890	COG3409	Peptidoglycan-binding domain 1 protein
IN839_RS24890	COG0860	N-Acetylmuramoyl-L-alanine amidase
IN839_RS24900	COG2124	cytochrome p450
IN839_RS24910	COG1309	transcriptional regulator
IN839_RS24930	COG1192	Involved in chromosome partitioning
IN839_RS24935	COG0357	Ribosomal RNA small subunit methyltransferase G
IN839_RS24945	COG0706	membrane insertase activity
IN839_RS24950	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IN839_RS25085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD