locus-tag	class	description
LA61_RS00010	COG0592	DNA-directed DNA polymerase activity
LA61_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LA61_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LA61_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LA61_RS00030	COG0187	DNA topoisomerase II activity
LA61_RS00115	COG0583	DNA-binding transcription factor activity
LA61_RS00130	COG0705	Rhomboid family
LA61_RS00130	COG0457	Tetratricopeptide repeat
LA61_RS00170	COG0515	serine threonine protein kinase
LA61_RS00170	COG2815	serine threonine protein kinase
LA61_RS00175	COG0515	serine threonine protein kinase
LA61_RS00180	COG0768	penicillin binding
LA61_RS00195	COG1716	ATPase activity
LA61_RS00200	COG1716	ATPase activity
LA61_RS00215	COG0754	glutathionylspermidine amidase activity
LA61_RS00225	COG1309	transcriptional regulator
LA61_RS00245	COG4842	Belongs to the WXG100 family
LA61_RS00265	COG0590	tRNA wobble adenosine to inosine editing
LA61_RS00275	COG0583	DNA-binding transcription factor activity
LA61_RS00280	COG1643	Atp-dependent helicase
LA61_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS00305	COG4585	Histidine kinase
LA61_RS00325	COG1960	acyl-CoA dehydrogenase activity
LA61_RS00370	COG2072	flavoprotein involved in K transport
LA61_RS00385	COG1414	Transcriptional regulator
LA61_RS00405	COG1053	succinate dehydrogenase
LA61_RS00435	COG1785	Belongs to the alkaline phosphatase family
LA61_RS00455	COG0070	glutamate synthase
LA61_RS00455	COG0069	glutamate synthase activity
LA61_RS00455	COG0067	glutamate synthase
LA61_RS00485	COG1796	DNA polymerase
LA61_RS00485	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LA61_RS00495	COG2072	flavoprotein involved in K transport
LA61_RS00505	COG2124	cytochrome p450
LA61_RS00520	COG1024	Enoyl-CoA hydratase
LA61_RS00550	COG2372	response to copper ion
LA61_RS00600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LA61_RS00620	COG5002	protein histidine kinase activity
LA61_RS00620	COG5001	Diguanylate cyclase
LA61_RS00620	COG3447	MASE1 domain protein
LA61_RS00630	COG1528	Iron-storage protein
LA61_RS00635	COG1528	Iron-storage protein
LA61_RS00640	COG1316	TRANSCRIPTIONal
LA61_RS00670	COG0406	alpha-ribazole phosphatase activity
LA61_RS00680	COG0028	Belongs to the TPP enzyme family
LA61_RS00710	COG2072	flavoprotein involved in K transport
LA61_RS00720	COG2072	flavoprotein involved in K transport
LA61_RS00740	COG1285	pathogenesis
LA61_RS00790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LA61_RS00790	COG2146	nitrite reductase [NAD(P)H] activity
LA61_RS00800	COG4133	protoheme IX ABC transporter activity
LA61_RS00805	COG2070	2-Nitropropane dioxygenase
LA61_RS00810	COG1942	4-Oxalocrotonate Tautomerase
LA61_RS00815	COG0583	DNA-binding transcription factor activity
LA61_RS00830	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS00845	COG0561	phosphatase activity
LA61_RS00865	COG1216	Glycosyl transferase, family 2
LA61_RS00870	COG0671	phosphoesterase, PA-phosphatase related
LA61_RS00875	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LA61_RS00880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LA61_RS00900	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
LA61_RS00905	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS00910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LA61_RS00910	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LA61_RS00910	COG3321	synthase
LA61_RS00915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA61_RS00965	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS00970	COG0277	FAD linked oxidase domain protein
LA61_RS00985	COG2376	Dihydroxyacetone kinase
LA61_RS00990	COG2267	carboxylic ester hydrolase activity
LA61_RS00995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LA61_RS01000	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LA61_RS01015	COG0671	phosphoesterase, PA-phosphatase related
LA61_RS01025	COG1216	Glycosyl transferase, family 2
LA61_RS01100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LA61_RS01105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LA61_RS01185	COG1960	acyl-CoA dehydrogenase activity
LA61_RS01205	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS01225	COG1174	glycine betaine transport
LA61_RS01240	COG0287	Prephenate dehydrogenase
LA61_RS01250	COG0590	tRNA wobble adenosine to inosine editing
LA61_RS01290	COG0343	queuine tRNA-ribosyltransferase activity
LA61_RS01310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LA61_RS01315	COG1793	dna ligase
LA61_RS01345	COG2271	Major facilitator Superfamily
LA61_RS01350	COG2130	NADP-dependent
LA61_RS01375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LA61_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS01440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LA61_RS01465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LA61_RS01475	COG0148	phosphopyruvate hydratase activity
LA61_RS01505	COG0860	N-Acetylmuramoyl-L-alanine amidase
LA61_RS01530	COG1492	cobalamin metabolic process
LA61_RS01555	COG1960	acyl-CoA dehydrogenase activity
LA61_RS01570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LA61_RS01600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LA61_RS01645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LA61_RS01655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LA61_RS01685	COG2070	2-Nitropropane dioxygenase
LA61_RS01730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LA61_RS01735	COG2971	BadF BadG BcrA BcrD
LA61_RS01740	COG2814	Major facilitator Superfamily
LA61_RS01760	COG3572	ergothioneine biosynthetic process
LA61_RS01765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LA61_RS01770	COG0121	glutamine amidotransferase
LA61_RS01775	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LA61_RS01780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LA61_RS01805	COG0183	Belongs to the thiolase family
LA61_RS01810	COG2030	dehydratase
LA61_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS01820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LA61_RS01830	COG1695	Transcriptional regulator
LA61_RS01840	COG0475	glutathione-regulated potassium exporter activity
LA61_RS01840	COG0569	domain protein
LA61_RS01860	COG0714	Associated with various cellular activities
LA61_RS01905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LA61_RS01910	COG1074	ATP-dependent DNA helicase activity
LA61_RS01915	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LA61_RS01925	COG2755	lipolytic protein G-D-S-L family
LA61_RS01955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LA61_RS01960	COG1408	metallophosphoesterase
LA61_RS01965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LA61_RS01995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LA61_RS02035	COG2945	thiolester hydrolase activity
LA61_RS02035	COG0596	Alpha beta hydrolase
LA61_RS02050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LA61_RS02055	COG0747	negative chemotaxis
LA61_RS02065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LA61_RS02135	COG0582	viral genome integration into host DNA
LA61_RS02180	COG2217	Heavy metal translocating P-type atpase
LA61_RS02190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LA61_RS02250	COG2132	Multicopper oxidase
LA61_RS02285	COG0596	Alpha beta hydrolase
LA61_RS02345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA61_RS02350	COG1309	transcriptional regulator
LA61_RS02355	COG0657	acetylesterase activity
LA61_RS02360	COG1902	pentaerythritol trinitrate reductase activity
LA61_RS02365	COG1205	dead DEAH box helicase
LA61_RS02365	COG1111	helicase
LA61_RS02370	COG1278	Cold shock
LA61_RS02380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LA61_RS02380	COG1754	DNA topoisomerase type I activity
LA61_RS02390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LA61_RS02500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LA61_RS02535	COG2027	D-alanyl-D-alanine carboxypeptidase
LA61_RS02570	COG1063	alcohol dehydrogenase
LA61_RS02580	COG2267	carboxylic ester hydrolase activity
LA61_RS02590	COG1309	transcriptional regulator
LA61_RS02605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LA61_RS02650	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LA61_RS02660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LA61_RS02680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LA61_RS02685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LA61_RS02725	COG4977	sequence-specific DNA binding
LA61_RS02730	COG1194	a g-specific adenine glycosylase
LA61_RS02740	COG1316	TRANSCRIPTIONal
LA61_RS02750	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LA61_RS02760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LA61_RS02780	COG1329	Transcriptional regulator
LA61_RS02785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LA61_RS02795	COG0215	cysteine-tRNA ligase activity
LA61_RS02805	COG0584	glycerophosphoryl diester phosphodiesterase
LA61_RS02815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LA61_RS02820	COG1120	ATPase activity
LA61_RS02825	COG0803	Belongs to the bacterial solute-binding protein 9 family
LA61_RS02835	COG1309	transcriptional regulator
LA61_RS02840	COG1960	acyl-CoA dehydrogenase activity
LA61_RS02855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LA61_RS02865	COG0346	lactoylglutathione lyase activity
LA61_RS02905	COG1960	acyl-CoA dehydrogenase activity
LA61_RS02910	COG1960	acyl-CoA dehydrogenase activity
LA61_RS02915	COG1960	acyl-CoA dehydrogenase activity
LA61_RS02920	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS02925	COG1960	acyl-CoA dehydrogenase activity
LA61_RS02940	COG0183	Belongs to the thiolase family
LA61_RS02970	COG1024	Enoyl-CoA hydratase
LA61_RS02975	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS03000	COG0183	Belongs to the thiolase family
LA61_RS03010	COG1960	acyl-CoA dehydrogenase activity
LA61_RS03015	COG1960	acyl-CoA dehydrogenase activity
LA61_RS03020	COG2030	dehydratase
LA61_RS03045	COG2030	dehydratase
LA61_RS03050	COG1053	succinate dehydrogenase
LA61_RS03060	COG3971	2-oxopent-4-enoate hydratase activity
LA61_RS03105	COG0651	ATP synthesis coupled electron transport
LA61_RS03115	COG2111	Na H antiporter
LA61_RS03115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LA61_RS03120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LA61_RS03140	COG0647	UMP catabolic process
LA61_RS03165	COG4221	oxidoreductase activity
LA61_RS03185	COG0459	protein refolding
LA61_RS03200	COG0714	Associated with various cellular activities
LA61_RS03250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA61_RS03265	COG4842	Belongs to the WXG100 family
LA61_RS03305	COG0745	RESPONSE REGULATOR receiver
LA61_RS03310	COG5000	phosphorelay sensor kinase activity
LA61_RS03310	COG5002	protein histidine kinase activity
LA61_RS03315	COG0537	adenosine 5'-monophosphoramidase activity
LA61_RS03320	COG0697	spore germination
LA61_RS03330	COG0596	Alpha beta hydrolase
LA61_RS03360	COG0436	Aminotransferase
LA61_RS03370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LA61_RS03395	COG0477	Major facilitator Superfamily
LA61_RS03400	COG0386	Belongs to the glutathione peroxidase family
LA61_RS03410	COG3573	Dehydrogenase
LA61_RS03420	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LA61_RS03435	COG2837	iron assimilation
LA61_RS03440	COG1362	aminopeptidase activity
LA61_RS03520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LA61_RS03530	COG0601	transmembrane transport
LA61_RS03535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LA61_RS03540	COG4172	Belongs to the ABC transporter superfamily
LA61_RS03570	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LA61_RS03580	COG0354	folic acid binding
LA61_RS03635	COG2897	thiosulfate sulfurtransferase activity
LA61_RS03655	COG0745	RESPONSE REGULATOR receiver
LA61_RS03675	COG0581	inorganic phosphate transmembrane transporter activity
LA61_RS03680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LA61_RS03685	COG0604	alcohol dehydrogenase
LA61_RS03740	COG1250	3-hydroxyacyl-CoA dehydrogenase
LA61_RS03765	COG0697	spore germination
LA61_RS03785	COG0442	prolyl-tRNA aminoacylation
LA61_RS04005	COG5651	PPE family
LA61_RS04010	COG0436	Aminotransferase
LA61_RS04030	COG0531	amino acid
LA61_RS04035	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LA61_RS04040	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS04050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA61_RS04055	COG2902	Dehydrogenase
LA61_RS04060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LA61_RS04065	COG1960	acyl-CoA dehydrogenase activity
LA61_RS04070	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS04075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA61_RS04085	COG0657	acetylesterase activity
LA61_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS04100	COG1902	pentaerythritol trinitrate reductase activity
LA61_RS04115	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS04130	COG1024	Enoyl-CoA hydratase
LA61_RS04175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA61_RS04180	COG0657	acetylesterase activity
LA61_RS04200	COG0183	Belongs to the thiolase family
LA61_RS04215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LA61_RS04235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA61_RS04250	COG1061	Type III restriction enzyme res subunit
LA61_RS04290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LA61_RS04310	COG1278	Cold shock
LA61_RS04350	COG2814	Major facilitator Superfamily
LA61_RS04415	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LA61_RS04420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LA61_RS04450	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS04450	COG2030	dehydratase
LA61_RS04455	COG1309	transcriptional regulator
LA61_RS04465	COG1024	Enoyl-CoA hydratase
LA61_RS04470	COG1250	3-hydroxyacyl-CoA dehydrogenase
LA61_RS04480	COG3396	Phenylacetate-CoA oxygenase
LA61_RS04485	COG3460	Phenylacetate-CoA oxygenase
LA61_RS04490	COG3396	Phenylacetate-CoA oxygenase
LA61_RS04495	COG2151	metal-sulfur cluster biosynthetic enzyme
LA61_RS04500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LA61_RS04525	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA61_RS04535	COG2124	cytochrome p450
LA61_RS04565	COG1764	response to oxidative stress
LA61_RS04570	COG1846	Transcriptional regulator
LA61_RS04575	COG1216	Glycosyl transferase, family 2
LA61_RS04580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LA61_RS04610	COG0259	pyridoxamine-phosphate oxidase activity
LA61_RS04620	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS04625	COG5651	PPE family
LA61_RS04630	COG2409	Drug exporters of the RND superfamily
LA61_RS04655	COG4977	sequence-specific DNA binding
LA61_RS04675	COG1846	Transcriptional regulator
LA61_RS04680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS04690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LA61_RS04695	COG0833	amino acid
LA61_RS04710	COG2186	Transcriptional regulator
LA61_RS04715	COG0545	Peptidyl-prolyl cis-trans isomerase
LA61_RS04755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LA61_RS04760	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LA61_RS04805	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS04820	COG3022	response to hydroperoxide
LA61_RS04830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LA61_RS04865	COG1309	transcriptional regulator
LA61_RS04900	COG1393	Belongs to the ArsC family
LA61_RS04905	COG0583	DNA-binding transcription factor activity
LA61_RS04945	COG0183	Belongs to the thiolase family
LA61_RS04990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA61_RS05030	COG0438	transferase activity, transferring glycosyl groups
LA61_RS05035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LA61_RS05050	COG2382	esterase
LA61_RS05080	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
LA61_RS05135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LA61_RS05145	COG2326	polyphosphate kinase activity
LA61_RS05160	COG2084	Dehydrogenase
LA61_RS05175	COG0523	cobalamin synthesis protein
LA61_RS05180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LA61_RS05185	COG0235	Class ii aldolase
LA61_RS05190	COG1396	sequence-specific DNA binding
LA61_RS05195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LA61_RS05200	COG0166	Belongs to the GPI family
LA61_RS05310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA61_RS05340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LA61_RS05345	COG0315	cyclic pyranopterin monophosphate synthase activity
LA61_RS05345	COG0521	Mo-molybdopterin cofactor biosynthetic process
LA61_RS05375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LA61_RS05380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LA61_RS05415	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LA61_RS05420	COG1104	cysteine desulfurase activity
LA61_RS05565	COG2235	arginine
LA61_RS05580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LA61_RS05595	COG1252	NADH dehydrogenase
LA61_RS05605	COG0084	hydrolase, TatD family'
LA61_RS05610	COG3583	domain protein
LA61_RS05625	COG0515	serine threonine protein kinase
LA61_RS05625	COG2815	serine threonine protein kinase
LA61_RS05645	COG2409	Drug exporters of the RND superfamily
LA61_RS05650	COG1846	Transcriptional regulator
LA61_RS05650	COG0456	acetyltransferase
LA61_RS05655	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LA61_RS05660	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS05675	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LA61_RS05710	COG1309	transcriptional regulator
LA61_RS05755	COG3956	TIGRFAM MazG family protein
LA61_RS05770	COG2837	iron assimilation
LA61_RS05775	COG2822	iron ion transport
LA61_RS05810	COG0596	Alpha beta hydrolase
LA61_RS05835	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS05845	COG0427	acetyl-CoA hydrolase
LA61_RS05895	COG1846	Transcriptional regulator
LA61_RS05910	COG1024	Enoyl-CoA hydratase
LA61_RS05935	COG0183	Belongs to the thiolase family
LA61_RS05940	COG2755	lipolytic protein G-D-S-L family
LA61_RS05945	COG0657	acetylesterase activity
LA61_RS05955	COG1714	RDD family
LA61_RS05970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LA61_RS05990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LA61_RS06000	COG1331	Highly conserved protein containing a thioredoxin domain
LA61_RS06005	COG3631	Ketosteroid isomerase-related protein
LA61_RS06020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LA61_RS06025	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS06030	COG2124	cytochrome p450
LA61_RS06050	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS06090	COG2272	Belongs to the type-B carboxylesterase lipase family
LA61_RS06100	COG1174	glycine betaine transport
LA61_RS06110	COG1174	glycine betaine transport
LA61_RS06155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LA61_RS06165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LA61_RS06170	COG0726	polysaccharide deacetylase
LA61_RS06240	COG1570	exodeoxyribonuclease VII activity
LA61_RS06250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LA61_RS06265	COG1966	Carbon starvation protein
LA61_RS06290	COG3189	MarR family transcriptional regulator
LA61_RS06295	COG0012	GTP binding
LA61_RS06315	COG2132	Multicopper oxidase
LA61_RS06325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LA61_RS06335	COG0488	(ABC) transporter
LA61_RS06395	COG2409	Drug exporters of the RND superfamily
LA61_RS06430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LA61_RS06450	COG1716	ATPase activity
LA61_RS06480	COG1051	belongs to the nudix hydrolase family
LA61_RS06505	COG1217	gtp-binding protein TYPA
LA61_RS06515	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LA61_RS06520	COG1609	Transcriptional regulator
LA61_RS06520	COG2207	Transcriptional regulator
LA61_RS06580	COG1902	pentaerythritol trinitrate reductase activity
LA61_RS06580	COG0446	pyridine nucleotide-disulphide oxidoreductase
LA61_RS06590	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LA61_RS06600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LA61_RS06605	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS06610	COG0506	proline dehydrogenase activity
LA61_RS06615	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS06640	COG2207	Transcriptional regulator
LA61_RS06655	COG1611	Belongs to the LOG family
LA61_RS06660	COG1611	Belongs to the LOG family
LA61_RS06665	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS06675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LA61_RS06685	COG0463	Glycosyl transferase, family 2
LA61_RS06700	COG0519	Catalyzes the synthesis of GMP from XMP
LA61_RS06710	COG0297	glycogen (starch) synthase activity
LA61_RS06745	COG3559	Exporter of polyketide antibiotics
LA61_RS06750	COG1131	(ABC) transporter
LA61_RS06755	COG1309	transcriptional regulator
LA61_RS06765	COG1595	DNA-templated transcription, initiation
LA61_RS06770	COG5662	AntiSigma factor
LA61_RS06775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LA61_RS06845	COG0598	Magnesium transport protein CorA
LA61_RS06850	COG1309	transcriptional regulator
LA61_RS06870	COG2095	MarC family integral membrane protein
LA61_RS06885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LA61_RS06890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LA61_RS06910	COG3835	regulator
LA61_RS06915	COG1073	alpha beta
LA61_RS06920	COG0567	Dehydrogenase, E1 component
LA61_RS06920	COG0508	dehydrogenase complex catalyzes the overall conversion of
LA61_RS06930	COG2814	Major facilitator Superfamily
LA61_RS06990	COG0277	FAD linked oxidase domain protein
LA61_RS06995	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS07010	COG0668	transmembrane transport
LA61_RS07100	COG2814	Major facilitator Superfamily
LA61_RS07130	COG0019	diaminopimelate decarboxylase activity
LA61_RS07135	COG0460	homoserine dehydrogenase
LA61_RS07140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LA61_RS07180	COG2890	protein-(glutamine-N5) methyltransferase activity
LA61_RS07190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LA61_RS07200	COG0356	it plays a direct role in the translocation of protons across the membrane
LA61_RS07205	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LA61_RS07230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LA61_RS07290	COG0346	lactoylglutathione lyase activity
LA61_RS07295	COG0183	Belongs to the thiolase family
LA61_RS07300	COG2409	Drug exporters of the RND superfamily
LA61_RS07315	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LA61_RS07320	COG0366	Alpha amylase catalytic
LA61_RS07325	COG0058	SHG alpha-glucan phosphorylase activity
LA61_RS07340	COG1335	isochorismatase
LA61_RS07350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LA61_RS07365	COG3191	aminopeptidase activity
LA61_RS07410	COG0604	alcohol dehydrogenase
LA61_RS07430	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS07445	COG0419	ATPase involved in DNA repair
LA61_RS07450	COG1024	Enoyl-CoA hydratase
LA61_RS07460	COG0243	molybdopterin cofactor binding
LA61_RS07475	COG2188	Transcriptional regulator
LA61_RS07540	COG0596	Alpha beta hydrolase
LA61_RS07545	COG3757	hydrolase, family 25
LA61_RS07565	COG1051	belongs to the nudix hydrolase family
LA61_RS07585	COG1309	transcriptional regulator
LA61_RS07600	COG4585	Histidine kinase
LA61_RS07605	COG2197	response regulator
LA61_RS07615	COG2239	Acts as a magnesium transporter
LA61_RS07625	COG0300	oxidoreductase activity
LA61_RS07635	COG0656	L-ascorbic acid biosynthetic process
LA61_RS07650	COG1376	ErfK ybiS ycfS ynhG family protein
LA61_RS07665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LA61_RS07670	COG0433	COG0433 Predicted ATPase
LA61_RS07685	COG0300	oxidoreductase activity
LA61_RS07700	COG1301	dicarboxylic acid transport
LA61_RS07710	COG0531	amino acid
LA61_RS07730	COG4424	Sulfotransferase
LA61_RS07735	COG3119	arylsulfatase activity
LA61_RS07770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LA61_RS07770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LA61_RS07805	COG2902	Dehydrogenase
LA61_RS07810	COG0824	Thioesterase
LA61_RS07825	COG0366	Alpha amylase catalytic
LA61_RS07860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LA61_RS07880	COG1309	transcriptional regulator
LA61_RS07895	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LA61_RS07915	COG0740	serine-type endopeptidase activity
LA61_RS07920	COG0740	serine-type endopeptidase activity
LA61_RS07970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LA61_RS07980	COG0674	pyruvate-flavodoxin oxidoreductase activity
LA61_RS07980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LA61_RS07985	COG1013	pyruvate-flavodoxin oxidoreductase activity
LA61_RS07995	COG1388	LysM domain
LA61_RS08025	COG0525	valine-tRNA ligase activity
LA61_RS08030	COG0285	dihydrofolate synthase activity
LA61_RS08045	COG1530	ribonuclease E activity
LA61_RS08075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LA61_RS08095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LA61_RS08100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LA61_RS08105	COG0542	response to heat
LA61_RS08115	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LA61_RS08125	COG0406	alpha-ribazole phosphatase activity
LA61_RS08130	COG2755	lipolytic protein G-D-S-L family
LA61_RS08150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA61_RS08185	COG2308	Evidence 4 Homologs of previously reported genes of
LA61_RS08195	COG1305	Transglutaminase-like
LA61_RS08225	COG3387	PFAM Glycoside hydrolase 15-related
LA61_RS08240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA61_RS08275	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LA61_RS08280	COG4208	sulfate ABC transporter
LA61_RS08340	COG0484	heat shock protein binding
LA61_RS08420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LA61_RS08435	COG0076	glutamate decarboxylase activity
LA61_RS08470	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS08520	COG0423	glycine-tRNA ligase activity
LA61_RS08525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LA61_RS08530	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LA61_RS08550	COG0358	DNA primase activity
LA61_RS08615	COG0745	RESPONSE REGULATOR receiver
LA61_RS08620	COG5002	protein histidine kinase activity
LA61_RS08980	COG3179	chitinase
LA61_RS09180	COG0488	(ABC) transporter
LA61_RS09205	COG1960	acyl-CoA dehydrogenase activity
LA61_RS09210	COG1335	isochorismatase
LA61_RS09220	COG0058	SHG alpha-glucan phosphorylase activity
LA61_RS09260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA61_RS09265	COG1960	acyl-CoA dehydrogenase activity
LA61_RS09270	COG0183	Belongs to the thiolase family
LA61_RS09290	COG1228	amidohydrolase
LA61_RS09320	COG0604	alcohol dehydrogenase
LA61_RS09320	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS09320	COG3321	synthase
LA61_RS09340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LA61_RS09370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LA61_RS09400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA61_RS09440	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LA61_RS09445	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LA61_RS09505	COG0714	Associated with various cellular activities
LA61_RS09525	COG0557	exoribonuclease II activity
LA61_RS09535	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS09560	COG0174	glutamine synthetase
LA61_RS09565	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LA61_RS09595	COG2205	protein histidine kinase activity
LA61_RS09625	COG0174	glutamine synthetase
LA61_RS09635	COG0477	Major facilitator Superfamily
LA61_RS09645	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LA61_RS09665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LA61_RS09670	COG0321	lipoyl(octanoyl) transferase activity
LA61_RS09685	COG1872	DUF167
LA61_RS09705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LA61_RS09715	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LA61_RS09720	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LA61_RS09750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LA61_RS09795	COG2010	Cytochrome c
LA61_RS09800	COG1845	cytochrome c oxidase, subunit III
LA61_RS09805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LA61_RS09840	COG2226	methyltransferase
LA61_RS09865	COG0003	Pfam Anion-transporting ATPase
LA61_RS09875	COG0204	Acyl-transferase
LA61_RS09880	COG5650	phosphatidylinositol metabolic process
LA61_RS09890	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LA61_RS09915	COG0142	geranyltranstransferase activity
LA61_RS09955	COG0768	penicillin binding
LA61_RS09975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LA61_RS09985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LA61_RS10000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LA61_RS10025	COG0640	Transcriptional regulator
LA61_RS10080	COG0154	amidase activity
LA61_RS10090	COG2957	Belongs to the agmatine deiminase family
LA61_RS10100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LA61_RS10110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LA61_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS10150	COG2814	Major facilitator Superfamily
LA61_RS10225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS10230	COG2030	dehydratase
LA61_RS10250	COG1024	Enoyl-CoA hydratase
LA61_RS10265	COG1309	transcriptional regulator
LA61_RS10290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA61_RS10340	COG2072	flavoprotein involved in K transport
LA61_RS10355	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS10360	COG1960	acyl-CoA dehydrogenase activity
LA61_RS10380	COG1960	acyl-CoA dehydrogenase activity
LA61_RS10415	COG3621	Patatin-like phospholipase
LA61_RS10470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LA61_RS10500	COG1968	undecaprenyl-diphosphatase activity
LA61_RS10535	COG1218	3'(2'),5'-bisphosphate nucleotidase
LA61_RS10545	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS10570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA61_RS10580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA61_RS10580	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LA61_RS10595	COG2860	membrane
LA61_RS10605	COG1410	methionine synthase
LA61_RS10605	COG0646	methionine synthase
LA61_RS10610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LA61_RS10620	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LA61_RS10655	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LA61_RS10660	COG1034	ATP synthesis coupled electron transport
LA61_RS10665	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LA61_RS10670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LA61_RS10750	COG0513	Belongs to the DEAD box helicase family
LA61_RS10790	COG0028	Belongs to the TPP enzyme family
LA61_RS10805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LA61_RS10810	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LA61_RS10815	COG4122	O-methyltransferase activity
LA61_RS10845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LA61_RS10850	COG4521	taurine ABC transporter
LA61_RS10855	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LA61_RS10890	COG2378	regulation of single-species biofilm formation
LA61_RS10895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LA61_RS10930	COG0300	oxidoreductase activity
LA61_RS10985	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LA61_RS10995	COG0463	Glycosyl transferase, family 2
LA61_RS11000	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS11025	COG0604	alcohol dehydrogenase
LA61_RS11025	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS11025	COG3321	synthase
LA61_RS11045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LA61_RS11055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LA61_RS11060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS11080	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LA61_RS11090	COG1404	Belongs to the peptidase S8 family
LA61_RS11105	COG4842	Belongs to the WXG100 family
LA61_RS11135	COG0464	growth
LA61_RS11155	COG0583	DNA-binding transcription factor activity
LA61_RS11185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LA61_RS11190	COG1169	isochorismate synthase
LA61_RS11195	COG0789	Transcriptional regulator
LA61_RS11200	COG1021	2,3-dihydroxybenzoate-AMP ligase
LA61_RS11230	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LA61_RS11255	COG0300	oxidoreductase activity
LA61_RS11255	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS11255	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS11255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA61_RS11255	COG3321	synthase
LA61_RS11275	COG2375	cellular response to nickel ion
LA61_RS11275	COG1132	(ABC) transporter
LA61_RS11280	COG0477	Major facilitator Superfamily
LA61_RS11285	COG5285	phytanoyl-CoA dioxygenase
LA61_RS11295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LA61_RS11300	COG0456	acetyltransferase
LA61_RS11320	COG2837	iron assimilation
LA61_RS11330	COG2186	Transcriptional regulator
LA61_RS11335	COG2807	transmembrane transport
LA61_RS11345	COG2409	Drug exporters of the RND superfamily
LA61_RS11350	COG3629	intracellular signal transduction
LA61_RS11355	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS11395	COG0475	glutathione-regulated potassium exporter activity
LA61_RS11460	COG0237	dephospho-CoA kinase activity
LA61_RS11460	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LA61_RS11645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LA61_RS11650	COG0072	phenylalanine-tRNA ligase activity
LA61_RS11650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LA61_RS11660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LA61_RS11665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LA61_RS11670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LA61_RS11675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LA61_RS11680	COG1438	arginine binding
LA61_RS11685	COG0137	argininosuccinate synthase activity
LA61_RS11725	COG2835	tetraacyldisaccharide 4'-kinase activity
LA61_RS11730	COG1309	transcriptional regulator
LA61_RS11735	COG2094	Belongs to the DNA glycosylase MPG family
LA61_RS11760	COG0647	UMP catabolic process
LA61_RS11775	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LA61_RS11795	COG0504	CTP synthase activity
LA61_RS11800	COG0494	nUDIX hydrolase
LA61_RS11820	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LA61_RS11835	COG1160	GTP binding
LA61_RS11845	COG1403	HNH endonuclease
LA61_RS11925	COG1053	succinate dehydrogenase
LA61_RS11925	COG3976	FMN-binding domain protein
LA61_RS11955	COG1960	acyl-CoA dehydrogenase activity
LA61_RS12015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LA61_RS12015	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LA61_RS12030	COG1253	flavin adenine dinucleotide binding
LA61_RS12035	COG1253	flavin adenine dinucleotide binding
LA61_RS12045	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LA61_RS12100	COG0832	Belongs to the urease beta subunit family
LA61_RS12110	COG0830	nickel cation binding
LA61_RS12125	COG1252	NADH dehydrogenase
LA61_RS12135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS12170	COG0243	molybdopterin cofactor binding
LA61_RS12180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LA61_RS12195	COG1058	Belongs to the CinA family
LA61_RS12195	COG1546	Belongs to the CinA family
LA61_RS12210	COG1741	Belongs to the pirin family
LA61_RS12230	COG1968	undecaprenyl-diphosphatase activity
LA61_RS12235	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LA61_RS12260	COG0277	FAD linked oxidase domain protein
LA61_RS12270	COG1309	transcriptional regulator
LA61_RS12285	COG1116	anion transmembrane transporter activity
LA61_RS12290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LA61_RS12295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LA61_RS12320	COG4290	ribonuclease
LA61_RS12350	COG0791	NLP P60 protein
LA61_RS12350	COG3883	PFAM NLP P60 protein
LA61_RS12385	COG0477	Major facilitator Superfamily
LA61_RS12405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LA61_RS12410	COG0069	glutamate synthase activity
LA61_RS12410	COG0067	glutamate synthase
LA61_RS12410	COG0070	glutamate synthase
LA61_RS12440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LA61_RS12455	COG1960	acyl-CoA dehydrogenase activity
LA61_RS12470	COG0443	Heat shock 70 kDa protein
LA61_RS12475	COG0596	Alpha beta hydrolase
LA61_RS12495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LA61_RS12505	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LA61_RS12525	COG2890	protein-(glutamine-N5) methyltransferase activity
LA61_RS12595	COG1982	Orn Lys Arg decarboxylase major
LA61_RS12650	COG0028	Belongs to the TPP enzyme family
LA61_RS12660	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS12680	COG1309	transcriptional regulator
LA61_RS12685	COG2957	Belongs to the agmatine deiminase family
LA61_RS12690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA61_RS12705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LA61_RS12750	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LA61_RS12765	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LA61_RS12785	COG0640	Transcriptional regulator
LA61_RS12795	COG0798	PFAM Bile acid sodium symporter
LA61_RS12800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LA61_RS12805	COG0390	transport system, permease component
LA61_RS12825	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS12830	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA61_RS12860	COG0745	RESPONSE REGULATOR receiver
LA61_RS12865	COG2205	protein histidine kinase activity
LA61_RS12880	COG1917	Cupin 2, conserved barrel domain protein
LA61_RS12885	COG3707	response regulator
LA61_RS12925	COG3467	pyridoxamine 5'-phosphate
LA61_RS12930	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
LA61_RS12950	COG0640	Transcriptional regulator
LA61_RS12970	COG1309	transcriptional regulator
LA61_RS12975	COG2072	flavoprotein involved in K transport
LA61_RS12985	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS12990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LA61_RS12995	COG0561	phosphatase activity
LA61_RS13000	COG0673	inositol 2-dehydrogenase activity
LA61_RS13005	COG0738	Major facilitator superfamily
LA61_RS13090	COG1271	oxidase subunit
LA61_RS13095	COG1294	oxidase, subunit
LA61_RS13100	COG4988	ABC transporter
LA61_RS13105	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LA61_RS13130	COG1946	Acyl-CoA thioesterase
LA61_RS13175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LA61_RS13180	COG1846	Transcriptional regulator
LA61_RS13210	COG2072	flavoprotein involved in K transport
LA61_RS13215	COG0657	acetylesterase activity
LA61_RS13270	COG0483	inositol monophosphate 1-phosphatase activity
LA61_RS13280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LA61_RS13285	COG0131	Imidazoleglycerol-phosphate dehydratase
LA61_RS13290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LA61_RS13315	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LA61_RS13330	COG1309	transcriptional regulator
LA61_RS13350	COG0583	DNA-binding transcription factor activity
LA61_RS13355	COG0579	oxidoreductase
LA61_RS13395	COG2755	lipolytic protein G-D-S-L family
LA61_RS13395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LA61_RS13450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LA61_RS13470	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LA61_RS13475	COG2814	Major facilitator Superfamily
LA61_RS13480	COG0583	DNA-binding transcription factor activity
LA61_RS13530	COG2239	Acts as a magnesium transporter
LA61_RS13560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LA61_RS13570	COG2304	oxidoreductase activity
LA61_RS13580	COG0714	Associated with various cellular activities
LA61_RS13590	COG0791	NLP P60 protein
LA61_RS13590	COG3883	PFAM NLP P60 protein
LA61_RS13600	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LA61_RS13605	COG1309	transcriptional regulator
LA61_RS13630	COG0488	(ABC) transporter
LA61_RS13645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LA61_RS13660	COG0456	acetyltransferase
LA61_RS13670	COG2151	metal-sulfur cluster biosynthetic enzyme
LA61_RS13685	COG0396	ATPase activity
LA61_RS13710	COG1131	(ABC) transporter
LA61_RS13750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LA61_RS13770	COG0583	DNA-binding transcription factor activity
LA61_RS13775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA61_RS13845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LA61_RS13905	COG0531	amino acid
LA61_RS13960	COG2011	ABC-type metal ion transport system permease component
LA61_RS13965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LA61_RS13985	COG0477	Major facilitator Superfamily
LA61_RS14020	COG0657	acetylesterase activity
LA61_RS14025	COG1953	Uracil, thiamine, allantoin
LA61_RS14035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LA61_RS14040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA61_RS14050	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LA61_RS14060	COG1758	RNA polymerase activity
LA61_RS14080	COG0284	orotidine-5'-phosphate decarboxylase activity
LA61_RS14085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LA61_RS14090	COG0505	Belongs to the CarA family
LA61_RS14110	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LA61_RS14130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LA61_RS14140	COG0006	proline dipeptidase activity
LA61_RS14155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LA61_RS14160	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LA61_RS14175	COG4106	trans-aconitate 2-methyltransferase activity
LA61_RS14190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LA61_RS14205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LA61_RS14255	COG0701	Predicted permease
LA61_RS14280	COG2272	Belongs to the type-B carboxylesterase lipase family
LA61_RS14320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LA61_RS14330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LA61_RS14340	COG0747	negative chemotaxis
LA61_RS14345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LA61_RS14360	COG2255	four-way junction helicase activity
LA61_RS14370	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LA61_RS14405	COG1946	Acyl-CoA thioesterase
LA61_RS14410	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LA61_RS14420	COG0438	transferase activity, transferring glycosyl groups
LA61_RS14460	COG4762	Protein conserved in bacteria
LA61_RS14515	COG1309	transcriptional regulator
LA61_RS14540	COG3878	Protein conserved in bacteria
LA61_RS14590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA61_RS14605	COG2080	2 iron, 2 sulfur cluster binding
LA61_RS14605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LA61_RS14620	COG0402	S-adenosylhomocysteine deaminase activity
LA61_RS14640	COG2233	PERMEase
LA61_RS14660	COG1953	Uracil, thiamine, allantoin
LA61_RS14670	COG1301	dicarboxylic acid transport
LA61_RS14680	COG4266	Belongs to the allantoicase family
LA61_RS14710	COG2267	carboxylic ester hydrolase activity
LA61_RS14715	COG1960	acyl-CoA dehydrogenase activity
LA61_RS14720	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS14735	COG0183	Belongs to the thiolase family
LA61_RS14750	COG0501	Belongs to the peptidase M48B family
LA61_RS14765	COG0477	Major facilitator Superfamily
LA61_RS14820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA61_RS14830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LA61_RS14870	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LA61_RS14895	COG3253	May function as heme-dependent peroxidase
LA61_RS14900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LA61_RS14905	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LA61_RS14915	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LA61_RS14930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LA61_RS14935	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LA61_RS14940	COG0531	amino acid
LA61_RS14945	COG0569	domain protein
LA61_RS14975	COG0702	epimerase
LA61_RS14990	COG0756	dUTP diphosphatase activity
LA61_RS15035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LA61_RS15085	COG3220	belongs to the UPF0276 family
LA61_RS15160	COG1388	LysM domain
LA61_RS15175	COG1960	acyl-CoA dehydrogenase activity
LA61_RS15185	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LA61_RS15205	COG1196	nuclear chromosome segregation
LA61_RS15225	COG1126	abc transporter atp-binding protein
LA61_RS15230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LA61_RS15235	COG0765	amino acid transport
LA61_RS15240	COG0765	amino acid transport
LA61_RS15290	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
LA61_RS15295	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
LA61_RS15310	COG1842	Phage shock protein A
LA61_RS15315	COG1396	sequence-specific DNA binding
LA61_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS15335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LA61_RS15390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LA61_RS15395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LA61_RS15410	COG3214	Protein conserved in bacteria
LA61_RS15450	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LA61_RS15460	COG0659	secondary active sulfate transmembrane transporter activity
LA61_RS15470	COG0686	Belongs to the AlaDH PNT family
LA61_RS15485	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS15555	COG2977	Belongs to the P-Pant transferase superfamily
LA61_RS15560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LA61_RS15580	COG1960	acyl-CoA dehydrogenase activity
LA61_RS15585	COG1960	acyl-CoA dehydrogenase activity
LA61_RS15590	COG1024	Enoyl-CoA hydratase
LA61_RS15615	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LA61_RS15640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LA61_RS15640	COG1017	nitric oxide dioxygenase activity
LA61_RS15645	COG1959	2 iron, 2 sulfur cluster binding
LA61_RS15690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LA61_RS15690	COG1648	precorrin-2 dehydrogenase activity
LA61_RS15715	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS15715	COG0604	alcohol dehydrogenase
LA61_RS15715	COG3321	synthase
LA61_RS15775	COG0579	oxidoreductase
LA61_RS15795	COG1492	cobalamin metabolic process
LA61_RS15805	COG1376	ErfK ybiS ycfS ynhG family protein
LA61_RS15830	COG0750	zinc metalloprotease
LA61_RS15855	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LA61_RS15920	COG0528	UMP kinase activity
LA61_RS15925	COG3973	AAA domain
LA61_RS15940	COG2723	6-phospho-beta-galactosidase activity
LA61_RS15975	COG1309	transcriptional regulator
LA61_RS16015	COG0583	DNA-binding transcription factor activity
LA61_RS16045	COG0792	nuclease activity
LA61_RS16105	COG0336	Belongs to the RNA methyltransferase TrmD family
LA61_RS16145	COG1686	Belongs to the peptidase S11 family
LA61_RS16165	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LA61_RS16185	COG1304	FMN binding
LA61_RS16235	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LA61_RS16240	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LA61_RS16260	COG0571	ribonuclease III activity
LA61_RS16270	COG3599	regulation of cell shape
LA61_RS16310	COG0742	ribosomal rna small subunit methyltransferase
LA61_RS16315	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LA61_RS16330	COG0657	acetylesterase activity
LA61_RS16335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS16355	COG2124	cytochrome p450
LA61_RS16370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LA61_RS16375	COG1461	Dihydroxyacetone kinase
LA61_RS16385	COG1024	Enoyl-CoA hydratase
LA61_RS16410	COG1181	Belongs to the D-alanine--D-alanine ligase family
LA61_RS16415	COG0626	cystathionine gamma-synthase activity
LA61_RS16420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LA61_RS16485	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA61_RS16500	COG2271	Major facilitator Superfamily
LA61_RS16535	COG0583	DNA-binding transcription factor activity
LA61_RS16545	COG0778	Nitroreductase
LA61_RS16560	COG1309	transcriptional regulator
LA61_RS16565	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA61_RS16570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA61_RS16575	COG2124	cytochrome p450
LA61_RS16605	COG0440	acetolactate synthase activity
LA61_RS16620	COG1748	Saccharopine dehydrogenase
LA61_RS16625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LA61_RS16645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA61_RS16665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LA61_RS16675	COG2272	Belongs to the type-B carboxylesterase lipase family
LA61_RS16690	COG0745	RESPONSE REGULATOR receiver
LA61_RS16695	COG2205	protein histidine kinase activity
LA61_RS16720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LA61_RS16750	COG1024	Enoyl-CoA hydratase
LA61_RS16755	COG0778	Nitroreductase
LA61_RS16765	COG2252	PERMEase
LA61_RS16805	COG2197	response regulator
LA61_RS16810	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LA61_RS16820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LA61_RS16845	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LA61_RS16860	COG1309	transcriptional regulator
LA61_RS16890	COG0110	maltose O-acetyltransferase activity
LA61_RS16895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LA61_RS16920	COG1119	ATPase activity
LA61_RS16930	COG2364	Membrane
LA61_RS16935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LA61_RS16950	COG4607	ABC-type enterochelin transport system periplasmic component
LA61_RS17000	COG1064	alcohol dehydrogenase
LA61_RS17020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LA61_RS17025	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS17085	COG0477	Major facilitator Superfamily
LA61_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS17135	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS17160	COG1335	isochorismatase
LA61_RS17170	COG2855	membrane
LA61_RS17180	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS17205	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS17210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LA61_RS17265	COG2272	Belongs to the type-B carboxylesterase lipase family
LA61_RS17280	COG0183	Belongs to the thiolase family
LA61_RS17315	COG1309	transcriptional regulator
LA61_RS17340	COG0789	Transcriptional regulator
LA61_RS17350	COG0028	Belongs to the TPP enzyme family
LA61_RS17370	COG2177	Part of the ABC transporter FtsEX involved in
LA61_RS17375	COG2884	Cell division ATP-binding protein ftsE
LA61_RS17385	COG0668	transmembrane transport
LA61_RS17425	COG0483	inositol monophosphate 1-phosphatase activity
LA61_RS17430	COG1960	acyl-CoA dehydrogenase activity
LA61_RS17435	COG1960	acyl-CoA dehydrogenase activity
LA61_RS17450	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS17460	COG0542	response to heat
LA61_RS17505	COG3480	Lon protease (S16) C-terminal proteolytic domain
LA61_RS17510	COG3011	Protein conserved in bacteria
LA61_RS17525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA61_RS17530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA61_RS17540	COG0300	oxidoreductase activity
LA61_RS17545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA61_RS17580	COG0475	glutathione-regulated potassium exporter activity
LA61_RS17580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LA61_RS17595	COG0596	Alpha beta hydrolase
LA61_RS17610	COG0745	RESPONSE REGULATOR receiver
LA61_RS17620	COG2146	nitrite reductase [NAD(P)H] activity
LA61_RS17620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LA61_RS17625	COG2223	nitrite transmembrane transporter activity
LA61_RS17665	COG0513	Belongs to the DEAD box helicase family
LA61_RS17680	COG0406	alpha-ribazole phosphatase activity
LA61_RS17700	COG1597	lipid kinase activity
LA61_RS17715	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LA61_RS17725	COG1595	DNA-templated transcription, initiation
LA61_RS17730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LA61_RS17735	COG2135	peptidase activity
LA61_RS17740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LA61_RS17745	COG1162	GTPase activity
LA61_RS17780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LA61_RS17875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LA61_RS17880	COG3321	synthase
LA61_RS17880	COG0604	alcohol dehydrogenase
LA61_RS17885	COG3321	synthase
LA61_RS17885	COG0604	alcohol dehydrogenase
LA61_RS17890	COG1960	acyl-CoA dehydrogenase activity
LA61_RS17900	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS17905	COG0653	protein targeting
LA61_RS17915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LA61_RS17920	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LA61_RS17930	COG1309	transcriptional regulator
LA61_RS17945	COG5401	PFAM Sporulation and spore germination
LA61_RS17950	COG5002	protein histidine kinase activity
LA61_RS17960	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS17965	COG1285	pathogenesis
LA61_RS17995	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LA61_RS18000	COG0531	amino acid
LA61_RS18010	COG1482	cell wall glycoprotein biosynthetic process
LA61_RS18040	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LA61_RS18045	COG0778	Nitroreductase
LA61_RS18045	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LA61_RS18060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LA61_RS18075	COG1316	TRANSCRIPTIONal
LA61_RS18095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LA61_RS18105	COG2175	clavaminate synthase activity
LA61_RS18130	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LA61_RS18130	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LA61_RS18140	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS18155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA61_RS18175	COG3265	gluconokinase activity
LA61_RS18180	COG1960	acyl-CoA dehydrogenase activity
LA61_RS18195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS18215	COG4770	biotin carboxylase activity
LA61_RS18225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LA61_RS18245	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS18250	COG1309	transcriptional regulator
LA61_RS18255	COG1201	RNA secondary structure unwinding
LA61_RS18270	COG0564	pseudouridine synthase activity
LA61_RS18290	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LA61_RS18290	COG1473	amidohydrolase
LA61_RS18305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LA61_RS18320	COG3883	PFAM NLP P60 protein
LA61_RS18320	COG0791	NLP P60 protein
LA61_RS18365	COG2009	succinate dehydrogenase
LA61_RS18380	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LA61_RS18385	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LA61_RS18390	COG1595	DNA-templated transcription, initiation
LA61_RS18405	COG1686	Belongs to the peptidase S11 family
LA61_RS18420	COG0708	Exodeoxyribonuclease III
LA61_RS18480	COG1733	regulation of RNA biosynthetic process
LA61_RS18485	COG2910	NAD(P)H-binding
LA61_RS18490	COG0842	Transport permease protein
LA61_RS18490	COG1716	ATPase activity
LA61_RS18490	COG1131	(ABC) transporter
LA61_RS18495	COG1357	PFAM Pentapeptide repeats (8 copies)
LA61_RS18510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LA61_RS18515	COG0587	DNA-directed DNA polymerase activity
LA61_RS18520	COG1073	alpha beta
LA61_RS18525	COG1309	transcriptional regulator
LA61_RS18590	COG0519	Catalyzes the synthesis of GMP from XMP
LA61_RS18590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LA61_RS18600	COG0516	GMP reductase activity
LA61_RS18660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LA61_RS18675	COG0456	acetyltransferase
LA61_RS18695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LA61_RS18700	COG0076	glutamate decarboxylase activity
LA61_RS18710	COG2267	carboxylic ester hydrolase activity
LA61_RS18715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LA61_RS18740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS18750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LA61_RS18755	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LA61_RS18790	COG1404	Belongs to the peptidase S8 family
LA61_RS18820	COG2267	carboxylic ester hydrolase activity
LA61_RS18875	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LA61_RS18880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA61_RS18890	COG2268	Band 7 protein
LA61_RS18900	COG1088	dTDP-glucose 4,6-dehydratase activity
LA61_RS18905	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LA61_RS18950	COG0616	signal peptide processing
LA61_RS18965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS18985	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LA61_RS18995	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LA61_RS19005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LA61_RS19020	COG2272	Belongs to the type-B carboxylesterase lipase family
LA61_RS19045	COG0477	Major facilitator Superfamily
LA61_RS19060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LA61_RS19100	COG0088	Forms part of the polypeptide exit tunnel
LA61_RS19105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LA61_RS19110	COG0051	transcription antitermination factor activity, RNA binding
LA61_RS19145	COG0531	amino acid
LA61_RS19175	COG0535	radical SAM domain protein
LA61_RS19200	COG1834	amidinotransferase
LA61_RS19205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LA61_RS19210	COG0531	amino acid
LA61_RS19255	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LA61_RS19260	COG1309	transcriptional regulator
LA61_RS19285	COG1024	Enoyl-CoA hydratase
LA61_RS19300	COG1960	acyl-CoA dehydrogenase activity
LA61_RS19330	COG1113	amino acid transport
LA61_RS19345	COG0085	RNA polymerase activity
LA61_RS19350	COG0243	molybdopterin cofactor binding
LA61_RS19405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LA61_RS19420	COG0277	FAD linked oxidase domain protein
LA61_RS19440	COG4941	Belongs to the sigma-70 factor family
LA61_RS19475	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LA61_RS19515	COG0783	Belongs to the Dps family
LA61_RS19520	COG0693	protein deglycase activity
LA61_RS19565	COG1404	Belongs to the peptidase S8 family
LA61_RS19585	COG1280	lysine exporter protein (LysE YggA)
LA61_RS19655	COG0501	Belongs to the peptidase M48B family
LA61_RS19660	COG0142	geranyltranstransferase activity
LA61_RS19665	COG0644	oxidoreductase
LA61_RS19675	COG0438	transferase activity, transferring glycosyl groups
LA61_RS19695	COG4948	Mandelate Racemase Muconate Lactonizing
LA61_RS19720	COG3706	GGDEF domain
LA61_RS19735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LA61_RS19745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LA61_RS19750	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS19755	COG4221	oxidoreductase activity
LA61_RS19800	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LA61_RS19805	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LA61_RS19815	COG0542	response to heat
LA61_RS19845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA61_RS19890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LA61_RS19895	COG1333	cytochrome c biogenesis protein
LA61_RS19900	COG0785	Cytochrome C biogenesis protein
LA61_RS19910	COG0406	alpha-ribazole phosphatase activity
LA61_RS19930	COG3590	peptidase
LA61_RS19980	COG1587	Uroporphyrinogen-III synthase
LA61_RS19980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LA61_RS20005	COG2030	dehydratase
LA61_RS20030	COG2070	2-Nitropropane dioxygenase
LA61_RS20050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LA61_RS20055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LA61_RS20160	COG1309	transcriptional regulator
LA61_RS20170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA61_RS20220	COG2072	flavoprotein involved in K transport
LA61_RS20235	COG2072	flavoprotein involved in K transport
LA61_RS20240	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS20245	COG0657	acetylesterase activity
LA61_RS20250	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA61_RS20260	COG0745	RESPONSE REGULATOR receiver
LA61_RS20265	COG5002	protein histidine kinase activity
LA61_RS20275	COG2072	flavoprotein involved in K transport
LA61_RS20290	COG0300	oxidoreductase activity
LA61_RS20345	COG2814	Major facilitator Superfamily
LA61_RS20440	COG2733	membrane
LA61_RS20450	COG2326	polyphosphate kinase activity
LA61_RS20455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LA61_RS20490	COG2224	Isocitrate lyase
LA61_RS20530	COG2226	methyltransferase
LA61_RS20580	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LA61_RS20615	COG0667	Aldo Keto reductase
LA61_RS20635	COG4552	Acetyltransferase involved in intracellular survival and related
LA61_RS20640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS20665	COG1505	serine-type exopeptidase activity
LA61_RS20685	COG1073	alpha beta
LA61_RS20690	COG2326	polyphosphate kinase activity
LA61_RS20705	COG2223	nitrite transmembrane transporter activity
LA61_RS20710	COG0640	Transcriptional regulator
LA61_RS20740	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LA61_RS20760	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LA61_RS20785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA61_RS20790	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA61_RS20795	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS20805	COG1960	acyl-CoA dehydrogenase activity
LA61_RS20810	COG1960	acyl-CoA dehydrogenase activity
LA61_RS20815	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS20825	COG2070	2-Nitropropane dioxygenase
LA61_RS20835	COG1024	Enoyl-CoA hydratase
LA61_RS20840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LA61_RS20845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS20880	COG4638	Rieske (2fe-2S)
LA61_RS20920	COG0175	sulfate reduction
LA61_RS20990	COG2814	Major facilitator Superfamily
LA61_RS21000	COG0351	phosphomethylpyrimidine kinase
LA61_RS21010	COG1252	NADH dehydrogenase
LA61_RS21020	COG1309	transcriptional regulator
LA61_RS21030	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS21065	COG0494	nUDIX hydrolase
LA61_RS21075	COG2234	aminopeptidase activity
LA61_RS21080	COG2234	aminopeptidase activity
LA61_RS21090	COG1131	(ABC) transporter
LA61_RS21095	COG2022	thiamine diphosphate biosynthetic process
LA61_RS21130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LA61_RS21135	COG0515	serine threonine protein kinase
LA61_RS21140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LA61_RS21170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LA61_RS21175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS21180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS21185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS21195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LA61_RS21200	COG1126	abc transporter atp-binding protein
LA61_RS21240	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LA61_RS21270	COG1994	Peptidase M50
LA61_RS21290	COG0586	Pfam SNARE associated Golgi protein
LA61_RS21320	COG4221	oxidoreductase activity
LA61_RS21340	COG0542	response to heat
LA61_RS21365	COG0789	Transcriptional regulator
LA61_RS21370	COG0484	heat shock protein binding
LA61_RS21375	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LA61_RS21445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LA61_RS21445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LA61_RS21485	COG2181	nitrate reductase activity
LA61_RS21485	COG0247	lactate metabolic process
LA61_RS21495	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LA61_RS21535	COG3345	alpha-galactosidase
LA61_RS21540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LA61_RS21545	COG1305	Transglutaminase-like
LA61_RS21560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LA61_RS21630	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS21640	COG0454	-acetyltransferase
LA61_RS21695	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS21700	COG1960	acyl-CoA dehydrogenase activity
LA61_RS21715	COG3268	Saccharopine dehydrogenase
LA61_RS21720	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS21725	COG3285	dna ligase
LA61_RS21725	COG1793	dna ligase
LA61_RS21730	COG0494	nUDIX hydrolase
LA61_RS21740	COG2902	Dehydrogenase
LA61_RS21745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LA61_RS21760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA61_RS21780	COG1309	transcriptional regulator
LA61_RS21790	COG0778	Nitroreductase
LA61_RS21795	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA61_RS21820	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA61_RS21825	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS21830	COG1396	sequence-specific DNA binding
LA61_RS21850	COG2267	carboxylic ester hydrolase activity
LA61_RS21855	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LA61_RS21870	COG4638	Rieske (2fe-2S)
LA61_RS21875	COG0604	alcohol dehydrogenase
LA61_RS21875	COG3321	synthase
LA61_RS21875	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS21880	COG3384	dioxygenase
LA61_RS21885	COG3971	2-oxopent-4-enoate hydratase activity
LA61_RS21900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LA61_RS21905	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS21940	COG1309	transcriptional regulator
LA61_RS21965	COG1309	transcriptional regulator
LA61_RS21970	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LA61_RS21985	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LA61_RS21990	COG1984	allophanate hydrolase subunit 2
LA61_RS22055	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LA61_RS22060	COG1802	Transcriptional regulator
LA61_RS22090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LA61_RS22100	COG0473	3-isopropylmalate dehydrogenase activity
LA61_RS22115	COG1053	succinate dehydrogenase
LA61_RS22135	COG0640	Transcriptional regulator
LA61_RS22185	COG2318	DinB family
LA61_RS22190	COG1960	acyl-CoA dehydrogenase activity
LA61_RS22205	COG1660	Displays ATPase and GTPase activities
LA61_RS22215	COG0183	Belongs to the thiolase family
LA61_RS22220	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS22225	COG2030	dehydratase
LA61_RS22240	COG0659	secondary active sulfate transmembrane transporter activity
LA61_RS22245	COG1309	transcriptional regulator
LA61_RS22250	COG0861	Integral membrane protein TerC family
LA61_RS22275	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS22290	COG1472	Belongs to the glycosyl hydrolase 3 family
LA61_RS22295	COG4941	Belongs to the sigma-70 factor family
LA61_RS22360	COG4981	capsule polysaccharide biosynthetic process
LA61_RS22400	COG0438	transferase activity, transferring glycosyl groups
LA61_RS22445	COG1250	3-hydroxyacyl-CoA dehydrogenase
LA61_RS22490	COG2197	response regulator
LA61_RS22495	COG3850	Histidine kinase
LA61_RS22515	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LA61_RS22545	COG2409	Drug exporters of the RND superfamily
LA61_RS22590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA61_RS22600	COG2197	response regulator
LA61_RS22630	COG2353	YceI-like domain
LA61_RS22650	COG2409	Drug exporters of the RND superfamily
LA61_RS22665	COG4552	Acetyltransferase involved in intracellular survival and related
LA61_RS22670	COG1832	CoA-binding protein
LA61_RS22685	COG3590	peptidase
LA61_RS22690	COG1376	ErfK ybiS ycfS ynhG family protein
LA61_RS22695	COG1960	acyl-CoA dehydrogenase activity
LA61_RS22705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA61_RS22715	COG1937	Protein conserved in bacteria
LA61_RS22740	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS22745	COG4122	O-methyltransferase activity
LA61_RS22760	COG2267	carboxylic ester hydrolase activity
LA61_RS22790	COG1704	LemA family
LA61_RS22800	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS22855	COG1024	Enoyl-CoA hydratase
LA61_RS22860	COG1802	Transcriptional regulator
LA61_RS22870	COG2267	carboxylic ester hydrolase activity
LA61_RS22875	COG1309	transcriptional regulator
LA61_RS22905	COG0435	Glutathione S-transferase
LA61_RS22945	COG1024	Enoyl-CoA hydratase
LA61_RS22955	COG2211	Major facilitator Superfamily
LA61_RS22960	COG2365	Tyrosine phosphatase family
LA61_RS23025	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS23030	COG1012	belongs to the aldehyde dehydrogenase family
LA61_RS23045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LA61_RS23050	COG1960	acyl-CoA dehydrogenase activity
LA61_RS23055	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LA61_RS23070	COG2226	methyltransferase
LA61_RS23085	COG3800	Transcriptional regulator
LA61_RS23085	COG1396	sequence-specific DNA binding
LA61_RS23095	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LA61_RS23135	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS23195	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LA61_RS23205	COG0129	dihydroxy-acid dehydratase activity
LA61_RS23225	COG2186	Transcriptional regulator
LA61_RS23255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LA61_RS23260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA61_RS23290	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS23330	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS23345	COG0318	PFAM AMP-dependent synthetase and ligase
LA61_RS23350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LA61_RS23355	COG1136	(ABC) transporter
LA61_RS23365	COG1104	cysteine desulfurase activity
LA61_RS23425	COG1309	transcriptional regulator
LA61_RS23435	COG1819	glycosyl
LA61_RS23590	COG3263	regulation of cellular component size
LA61_RS23670	COG1595	DNA-templated transcription, initiation
LA61_RS23680	COG0783	Belongs to the Dps family
LA61_RS23720	COG1252	NADH dehydrogenase
LA61_RS23740	COG1937	Protein conserved in bacteria
LA61_RS23765	COG1403	HNH endonuclease
LA61_RS23840	COG2140	Oxalate decarboxylase
LA61_RS23865	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LA61_RS23885	COG1376	ErfK ybiS ycfS ynhG family protein
LA61_RS23905	COG2030	dehydratase
LA61_RS23910	COG0488	(ABC) transporter
LA61_RS23915	COG3757	hydrolase, family 25
LA61_RS23980	COG0583	DNA-binding transcription factor activity
LA61_RS23990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA61_RS24005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LA61_RS24010	COG3757	hydrolase, family 25
LA61_RS24215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LA61_RS24245	COG0745	RESPONSE REGULATOR receiver
LA61_RS24250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LA61_RS24310	COG0640	Transcriptional regulator
LA61_RS24315	COG0640	Transcriptional regulator
LA61_RS24320	COG0798	PFAM Bile acid sodium symporter
LA61_RS24325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LA61_RS24330	COG0446	pyridine nucleotide-disulphide oxidoreductase
LA61_RS24340	COG0717	Belongs to the dCTP deaminase family
LA61_RS24380	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LA61_RS24405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LA61_RS24415	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LA61_RS24450	COG0454	-acetyltransferase
LA61_RS24495	COG0629	single-stranded DNA binding
LA61_RS24510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LA61_RS24540	COG1260	myo-inositol-1-phosphate synthase
LA61_RS24550	COG1113	amino acid transport
LA61_RS24565	COG1309	transcriptional regulator
LA61_RS24570	COG1028	Short-chain dehydrogenase reductase Sdr
LA61_RS24585	COG0508	dehydrogenase complex catalyzes the overall conversion of
LA61_RS24590	COG0022	dehydrogenase e1 component
LA61_RS24605	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
LA61_RS24610	COG2311	Membrane
LA61_RS24675	COG0617	tRNA 3'-terminal CCA addition
LA61_RS24695	COG1595	DNA-templated transcription, initiation
LA61_RS24715	COG0860	N-Acetylmuramoyl-L-alanine amidase
LA61_RS24715	COG3409	Peptidoglycan-binding domain 1 protein
LA61_RS24725	COG2124	cytochrome p450
LA61_RS24735	COG1309	transcriptional regulator
LA61_RS24755	COG1192	Involved in chromosome partitioning
LA61_RS24760	COG0357	Ribosomal RNA small subunit methyltransferase G
LA61_RS24770	COG0706	membrane insertase activity
LA61_RS24840	COG2814	Major facilitator Superfamily
LA61_RS24895	COG0765	amino acid transport
LA61_RS24975	COG1902	pentaerythritol trinitrate reductase activity
LA61_RS25330	COG1403	HNH endonuclease
LA61_RS25390	COG1254	Belongs to the acylphosphatase family
LA61_RS25460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LA61_RS25510	COG1414	Transcriptional regulator
LA61_RS25575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA61_RS25665	COG0759	Could be involved in insertion of integral membrane proteins into the membrane