locus-tag	class	description
LA62_RS00010	COG0592	DNA-directed DNA polymerase activity
LA62_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LA62_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LA62_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LA62_RS00030	COG0187	DNA topoisomerase II activity
LA62_RS00115	COG0583	DNA-binding transcription factor activity
LA62_RS00130	COG0705	Rhomboid family
LA62_RS00130	COG0457	Tetratricopeptide repeat
LA62_RS00170	COG0515	serine threonine protein kinase
LA62_RS00170	COG2815	serine threonine protein kinase
LA62_RS00175	COG0515	serine threonine protein kinase
LA62_RS00180	COG0768	penicillin binding
LA62_RS00195	COG1716	ATPase activity
LA62_RS00200	COG1716	ATPase activity
LA62_RS00215	COG0754	glutathionylspermidine amidase activity
LA62_RS00225	COG1309	transcriptional regulator
LA62_RS00245	COG4842	Belongs to the WXG100 family
LA62_RS00265	COG0590	tRNA wobble adenosine to inosine editing
LA62_RS00275	COG0583	DNA-binding transcription factor activity
LA62_RS00280	COG1643	Atp-dependent helicase
LA62_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS00305	COG4585	Histidine kinase
LA62_RS00325	COG1960	acyl-CoA dehydrogenase activity
LA62_RS00370	COG2072	flavoprotein involved in K transport
LA62_RS00380	COG0346	lactoylglutathione lyase activity
LA62_RS00385	COG1414	Transcriptional regulator
LA62_RS00405	COG1053	succinate dehydrogenase
LA62_RS00435	COG1785	Belongs to the alkaline phosphatase family
LA62_RS00455	COG0070	glutamate synthase
LA62_RS00455	COG0069	glutamate synthase activity
LA62_RS00455	COG0067	glutamate synthase
LA62_RS00485	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LA62_RS00485	COG1796	DNA polymerase
LA62_RS00495	COG2072	flavoprotein involved in K transport
LA62_RS00505	COG2124	cytochrome p450
LA62_RS00520	COG1024	Enoyl-CoA hydratase
LA62_RS00545	COG2372	response to copper ion
LA62_RS00590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LA62_RS00610	COG5002	protein histidine kinase activity
LA62_RS00610	COG5001	Diguanylate cyclase
LA62_RS00610	COG3447	MASE1 domain protein
LA62_RS00620	COG1528	Iron-storage protein
LA62_RS00625	COG1528	Iron-storage protein
LA62_RS00630	COG1316	TRANSCRIPTIONal
LA62_RS00660	COG0406	alpha-ribazole phosphatase activity
LA62_RS00670	COG0028	Belongs to the TPP enzyme family
LA62_RS00700	COG2072	flavoprotein involved in K transport
LA62_RS00710	COG2072	flavoprotein involved in K transport
LA62_RS00730	COG1285	pathogenesis
LA62_RS00780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LA62_RS00780	COG2146	nitrite reductase [NAD(P)H] activity
LA62_RS00790	COG4133	protoheme IX ABC transporter activity
LA62_RS00795	COG2070	2-Nitropropane dioxygenase
LA62_RS00800	COG1942	4-Oxalocrotonate Tautomerase
LA62_RS00805	COG0583	DNA-binding transcription factor activity
LA62_RS00820	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS00835	COG0561	phosphatase activity
LA62_RS00855	COG1216	Glycosyl transferase, family 2
LA62_RS00860	COG0671	phosphoesterase, PA-phosphatase related
LA62_RS00865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LA62_RS00870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LA62_RS00890	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
LA62_RS00895	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS00900	COG3321	synthase
LA62_RS00900	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LA62_RS00900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LA62_RS00905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA62_RS00955	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS00960	COG0277	FAD linked oxidase domain protein
LA62_RS00975	COG2376	Dihydroxyacetone kinase
LA62_RS00980	COG2267	carboxylic ester hydrolase activity
LA62_RS00985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LA62_RS00990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LA62_RS01005	COG0671	phosphoesterase, PA-phosphatase related
LA62_RS01015	COG1216	Glycosyl transferase, family 2
LA62_RS01090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LA62_RS01095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LA62_RS01195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LA62_RS01270	COG1960	acyl-CoA dehydrogenase activity
LA62_RS01290	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS01310	COG1174	glycine betaine transport
LA62_RS01325	COG0287	Prephenate dehydrogenase
LA62_RS01335	COG0590	tRNA wobble adenosine to inosine editing
LA62_RS01375	COG0343	queuine tRNA-ribosyltransferase activity
LA62_RS01395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LA62_RS01400	COG1793	dna ligase
LA62_RS01430	COG2271	Major facilitator Superfamily
LA62_RS01435	COG2130	NADP-dependent
LA62_RS01460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LA62_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS01525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LA62_RS01550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LA62_RS01560	COG0148	phosphopyruvate hydratase activity
LA62_RS01590	COG0860	N-Acetylmuramoyl-L-alanine amidase
LA62_RS01615	COG1492	cobalamin metabolic process
LA62_RS01640	COG1960	acyl-CoA dehydrogenase activity
LA62_RS01655	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LA62_RS01685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LA62_RS01730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LA62_RS01740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LA62_RS01770	COG2070	2-Nitropropane dioxygenase
LA62_RS01815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LA62_RS01820	COG2971	BadF BadG BcrA BcrD
LA62_RS01825	COG2814	Major facilitator Superfamily
LA62_RS01845	COG3572	ergothioneine biosynthetic process
LA62_RS01850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LA62_RS01855	COG0121	glutamine amidotransferase
LA62_RS01860	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LA62_RS01865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LA62_RS01890	COG0183	Belongs to the thiolase family
LA62_RS01895	COG2030	dehydratase
LA62_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS01905	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LA62_RS01915	COG1695	Transcriptional regulator
LA62_RS01925	COG0475	glutathione-regulated potassium exporter activity
LA62_RS01925	COG0569	domain protein
LA62_RS01945	COG0714	Associated with various cellular activities
LA62_RS01990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LA62_RS01995	COG1074	ATP-dependent DNA helicase activity
LA62_RS02000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LA62_RS02010	COG2755	lipolytic protein G-D-S-L family
LA62_RS02040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LA62_RS02045	COG1408	metallophosphoesterase
LA62_RS02050	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LA62_RS02080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LA62_RS02120	COG2945	thiolester hydrolase activity
LA62_RS02120	COG0596	Alpha beta hydrolase
LA62_RS02135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LA62_RS02140	COG0747	negative chemotaxis
LA62_RS02150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LA62_RS02220	COG0582	viral genome integration into host DNA
LA62_RS02265	COG2217	Heavy metal translocating P-type atpase
LA62_RS02275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LA62_RS02335	COG2132	Multicopper oxidase
LA62_RS02370	COG0596	Alpha beta hydrolase
LA62_RS02430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA62_RS02435	COG1309	transcriptional regulator
LA62_RS02440	COG0657	acetylesterase activity
LA62_RS02445	COG1902	pentaerythritol trinitrate reductase activity
LA62_RS02450	COG1111	helicase
LA62_RS02450	COG1205	dead DEAH box helicase
LA62_RS02455	COG1278	Cold shock
LA62_RS02465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LA62_RS02465	COG1754	DNA topoisomerase type I activity
LA62_RS02475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LA62_RS02550	COG1215	transferase activity, transferring glycosyl groups
LA62_RS02585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LA62_RS02620	COG2027	D-alanyl-D-alanine carboxypeptidase
LA62_RS02655	COG1063	alcohol dehydrogenase
LA62_RS02665	COG2267	carboxylic ester hydrolase activity
LA62_RS02675	COG1309	transcriptional regulator
LA62_RS02690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LA62_RS02735	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LA62_RS02745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LA62_RS02765	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LA62_RS02770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LA62_RS02810	COG4977	sequence-specific DNA binding
LA62_RS02815	COG1194	a g-specific adenine glycosylase
LA62_RS02825	COG1316	TRANSCRIPTIONal
LA62_RS02835	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LA62_RS02845	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LA62_RS02865	COG1329	Transcriptional regulator
LA62_RS02870	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LA62_RS02880	COG0215	cysteine-tRNA ligase activity
LA62_RS02890	COG0584	glycerophosphoryl diester phosphodiesterase
LA62_RS02900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LA62_RS02905	COG1120	ATPase activity
LA62_RS02910	COG0803	Belongs to the bacterial solute-binding protein 9 family
LA62_RS02920	COG1309	transcriptional regulator
LA62_RS02925	COG1960	acyl-CoA dehydrogenase activity
LA62_RS02940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LA62_RS02950	COG0346	lactoylglutathione lyase activity
LA62_RS02990	COG1960	acyl-CoA dehydrogenase activity
LA62_RS02995	COG1960	acyl-CoA dehydrogenase activity
LA62_RS03000	COG1960	acyl-CoA dehydrogenase activity
LA62_RS03005	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS03010	COG1960	acyl-CoA dehydrogenase activity
LA62_RS03025	COG0183	Belongs to the thiolase family
LA62_RS03055	COG1024	Enoyl-CoA hydratase
LA62_RS03060	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS03065	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS03085	COG0183	Belongs to the thiolase family
LA62_RS03095	COG1960	acyl-CoA dehydrogenase activity
LA62_RS03100	COG1960	acyl-CoA dehydrogenase activity
LA62_RS03105	COG2030	dehydratase
LA62_RS03130	COG2030	dehydratase
LA62_RS03135	COG1053	succinate dehydrogenase
LA62_RS03145	COG3971	2-oxopent-4-enoate hydratase activity
LA62_RS03190	COG0651	ATP synthesis coupled electron transport
LA62_RS03200	COG2111	Na H antiporter
LA62_RS03200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LA62_RS03205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LA62_RS03225	COG0647	UMP catabolic process
LA62_RS03250	COG4221	oxidoreductase activity
LA62_RS03270	COG0459	protein refolding
LA62_RS03285	COG0714	Associated with various cellular activities
LA62_RS03335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA62_RS03350	COG4842	Belongs to the WXG100 family
LA62_RS03390	COG0745	RESPONSE REGULATOR receiver
LA62_RS03395	COG5000	phosphorelay sensor kinase activity
LA62_RS03395	COG5002	protein histidine kinase activity
LA62_RS03400	COG0537	adenosine 5'-monophosphoramidase activity
LA62_RS03405	COG0697	spore germination
LA62_RS03415	COG0596	Alpha beta hydrolase
LA62_RS03445	COG0436	Aminotransferase
LA62_RS03455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LA62_RS03480	COG0477	Major facilitator Superfamily
LA62_RS03485	COG0386	Belongs to the glutathione peroxidase family
LA62_RS03495	COG3573	Dehydrogenase
LA62_RS03505	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LA62_RS03520	COG2837	iron assimilation
LA62_RS03525	COG1362	aminopeptidase activity
LA62_RS03605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LA62_RS03615	COG0601	transmembrane transport
LA62_RS03620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LA62_RS03625	COG4172	Belongs to the ABC transporter superfamily
LA62_RS03655	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LA62_RS03665	COG0354	folic acid binding
LA62_RS03720	COG2897	thiosulfate sulfurtransferase activity
LA62_RS03740	COG0745	RESPONSE REGULATOR receiver
LA62_RS03760	COG0581	inorganic phosphate transmembrane transporter activity
LA62_RS03765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LA62_RS03770	COG0604	alcohol dehydrogenase
LA62_RS03825	COG1250	3-hydroxyacyl-CoA dehydrogenase
LA62_RS03850	COG0697	spore germination
LA62_RS03870	COG0442	prolyl-tRNA aminoacylation
LA62_RS03875	COG2814	Major facilitator Superfamily
LA62_RS04090	COG5651	PPE family
LA62_RS04095	COG0436	Aminotransferase
LA62_RS04115	COG0531	amino acid
LA62_RS04120	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LA62_RS04125	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS04135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA62_RS04140	COG2902	Dehydrogenase
LA62_RS04145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LA62_RS04150	COG1960	acyl-CoA dehydrogenase activity
LA62_RS04155	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS04160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA62_RS04170	COG0657	acetylesterase activity
LA62_RS04175	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS04185	COG1902	pentaerythritol trinitrate reductase activity
LA62_RS04200	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS04215	COG1024	Enoyl-CoA hydratase
LA62_RS04260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA62_RS04265	COG0657	acetylesterase activity
LA62_RS04285	COG0183	Belongs to the thiolase family
LA62_RS04300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LA62_RS04320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA62_RS04335	COG1061	Type III restriction enzyme res subunit
LA62_RS04375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LA62_RS04395	COG1278	Cold shock
LA62_RS04435	COG2814	Major facilitator Superfamily
LA62_RS04505	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LA62_RS04510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LA62_RS04540	COG2030	dehydratase
LA62_RS04540	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS04545	COG1309	transcriptional regulator
LA62_RS04555	COG1024	Enoyl-CoA hydratase
LA62_RS04560	COG1250	3-hydroxyacyl-CoA dehydrogenase
LA62_RS04570	COG3396	Phenylacetate-CoA oxygenase
LA62_RS04575	COG3460	Phenylacetate-CoA oxygenase
LA62_RS04580	COG3396	Phenylacetate-CoA oxygenase
LA62_RS04585	COG2151	metal-sulfur cluster biosynthetic enzyme
LA62_RS04590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LA62_RS04615	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA62_RS04625	COG2124	cytochrome p450
LA62_RS04655	COG1764	response to oxidative stress
LA62_RS04660	COG1846	Transcriptional regulator
LA62_RS04665	COG1216	Glycosyl transferase, family 2
LA62_RS04670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LA62_RS04700	COG0259	pyridoxamine-phosphate oxidase activity
LA62_RS04710	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS04715	COG5651	PPE family
LA62_RS04720	COG2409	Drug exporters of the RND superfamily
LA62_RS04745	COG4977	sequence-specific DNA binding
LA62_RS04765	COG1846	Transcriptional regulator
LA62_RS04770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS04780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LA62_RS04785	COG0833	amino acid
LA62_RS04800	COG2186	Transcriptional regulator
LA62_RS04805	COG0545	Peptidyl-prolyl cis-trans isomerase
LA62_RS04845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LA62_RS04850	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LA62_RS04895	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS04910	COG3022	response to hydroperoxide
LA62_RS04920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LA62_RS04955	COG1309	transcriptional regulator
LA62_RS04990	COG1393	Belongs to the ArsC family
LA62_RS04995	COG0583	DNA-binding transcription factor activity
LA62_RS05035	COG0183	Belongs to the thiolase family
LA62_RS05080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA62_RS05120	COG0438	transferase activity, transferring glycosyl groups
LA62_RS05125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LA62_RS05140	COG2382	esterase
LA62_RS05170	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
LA62_RS05180	COG1846	Transcriptional regulator
LA62_RS05225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LA62_RS05235	COG2326	polyphosphate kinase activity
LA62_RS05250	COG2084	Dehydrogenase
LA62_RS05265	COG0523	cobalamin synthesis protein
LA62_RS05270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LA62_RS05275	COG0235	Class ii aldolase
LA62_RS05280	COG1396	sequence-specific DNA binding
LA62_RS05285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LA62_RS05290	COG0166	Belongs to the GPI family
LA62_RS05400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA62_RS05430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LA62_RS05435	COG0521	Mo-molybdopterin cofactor biosynthetic process
LA62_RS05435	COG0315	cyclic pyranopterin monophosphate synthase activity
LA62_RS05465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LA62_RS05470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LA62_RS05505	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LA62_RS05510	COG1104	cysteine desulfurase activity
LA62_RS05650	COG2235	arginine
LA62_RS05665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LA62_RS05680	COG1252	NADH dehydrogenase
LA62_RS05690	COG0084	hydrolase, TatD family'
LA62_RS05695	COG3583	domain protein
LA62_RS05710	COG2815	serine threonine protein kinase
LA62_RS05710	COG0515	serine threonine protein kinase
LA62_RS05730	COG2409	Drug exporters of the RND superfamily
LA62_RS05735	COG1846	Transcriptional regulator
LA62_RS05735	COG0456	acetyltransferase
LA62_RS05740	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LA62_RS05745	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS05760	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LA62_RS05795	COG1309	transcriptional regulator
LA62_RS05845	COG3956	TIGRFAM MazG family protein
LA62_RS05860	COG2837	iron assimilation
LA62_RS05865	COG2822	iron ion transport
LA62_RS05900	COG0596	Alpha beta hydrolase
LA62_RS05925	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS05935	COG0427	acetyl-CoA hydrolase
LA62_RS05985	COG1846	Transcriptional regulator
LA62_RS06000	COG1024	Enoyl-CoA hydratase
LA62_RS06025	COG0183	Belongs to the thiolase family
LA62_RS06030	COG2755	lipolytic protein G-D-S-L family
LA62_RS06035	COG0657	acetylesterase activity
LA62_RS06045	COG1714	RDD family
LA62_RS06060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LA62_RS06080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LA62_RS06090	COG1331	Highly conserved protein containing a thioredoxin domain
LA62_RS06095	COG3631	Ketosteroid isomerase-related protein
LA62_RS06110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LA62_RS06115	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS06120	COG2124	cytochrome p450
LA62_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS06180	COG2272	Belongs to the type-B carboxylesterase lipase family
LA62_RS06190	COG1174	glycine betaine transport
LA62_RS06200	COG1174	glycine betaine transport
LA62_RS06245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LA62_RS06255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LA62_RS06260	COG0726	polysaccharide deacetylase
LA62_RS06330	COG1570	exodeoxyribonuclease VII activity
LA62_RS06340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LA62_RS06355	COG1966	Carbon starvation protein
LA62_RS06380	COG3189	MarR family transcriptional regulator
LA62_RS06385	COG0012	GTP binding
LA62_RS06405	COG2132	Multicopper oxidase
LA62_RS06415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LA62_RS06425	COG0488	(ABC) transporter
LA62_RS06485	COG2409	Drug exporters of the RND superfamily
LA62_RS06520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LA62_RS06540	COG1716	ATPase activity
LA62_RS06575	COG1051	belongs to the nudix hydrolase family
LA62_RS06600	COG1217	gtp-binding protein TYPA
LA62_RS06610	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LA62_RS06615	COG2207	Transcriptional regulator
LA62_RS06615	COG1609	Transcriptional regulator
LA62_RS06675	COG1902	pentaerythritol trinitrate reductase activity
LA62_RS06675	COG0446	pyridine nucleotide-disulphide oxidoreductase
LA62_RS06685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LA62_RS06695	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LA62_RS06700	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS06705	COG0506	proline dehydrogenase activity
LA62_RS06710	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS06735	COG2207	Transcriptional regulator
LA62_RS06750	COG1611	Belongs to the LOG family
LA62_RS06755	COG1611	Belongs to the LOG family
LA62_RS06760	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS06770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LA62_RS06780	COG0463	Glycosyl transferase, family 2
LA62_RS06795	COG0519	Catalyzes the synthesis of GMP from XMP
LA62_RS06805	COG0297	glycogen (starch) synthase activity
LA62_RS06840	COG3559	Exporter of polyketide antibiotics
LA62_RS06845	COG1131	(ABC) transporter
LA62_RS06850	COG1309	transcriptional regulator
LA62_RS06860	COG1595	DNA-templated transcription, initiation
LA62_RS06865	COG5662	AntiSigma factor
LA62_RS06870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LA62_RS06940	COG0598	Magnesium transport protein CorA
LA62_RS06945	COG1309	transcriptional regulator
LA62_RS06965	COG2095	MarC family integral membrane protein
LA62_RS06980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LA62_RS06985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LA62_RS07005	COG3835	regulator
LA62_RS07010	COG1073	alpha beta
LA62_RS07015	COG0567	Dehydrogenase, E1 component
LA62_RS07015	COG0508	dehydrogenase complex catalyzes the overall conversion of
LA62_RS07025	COG2814	Major facilitator Superfamily
LA62_RS07085	COG0277	FAD linked oxidase domain protein
LA62_RS07090	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS07105	COG0668	transmembrane transport
LA62_RS07195	COG2814	Major facilitator Superfamily
LA62_RS07225	COG0019	diaminopimelate decarboxylase activity
LA62_RS07230	COG0460	homoserine dehydrogenase
LA62_RS07235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LA62_RS07275	COG2890	protein-(glutamine-N5) methyltransferase activity
LA62_RS07285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LA62_RS07295	COG0356	it plays a direct role in the translocation of protons across the membrane
LA62_RS07300	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LA62_RS07325	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LA62_RS07385	COG0346	lactoylglutathione lyase activity
LA62_RS07390	COG0183	Belongs to the thiolase family
LA62_RS07395	COG2409	Drug exporters of the RND superfamily
LA62_RS07410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LA62_RS07415	COG0366	Alpha amylase catalytic
LA62_RS07420	COG0058	SHG alpha-glucan phosphorylase activity
LA62_RS07435	COG1335	isochorismatase
LA62_RS07445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LA62_RS07460	COG3191	aminopeptidase activity
LA62_RS07505	COG0604	alcohol dehydrogenase
LA62_RS07525	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS07540	COG0419	ATPase involved in DNA repair
LA62_RS07545	COG1024	Enoyl-CoA hydratase
LA62_RS07555	COG0243	molybdopterin cofactor binding
LA62_RS07570	COG2188	Transcriptional regulator
LA62_RS07635	COG0596	Alpha beta hydrolase
LA62_RS07640	COG3757	hydrolase, family 25
LA62_RS07655	COG1051	belongs to the nudix hydrolase family
LA62_RS07675	COG1309	transcriptional regulator
LA62_RS07690	COG4585	Histidine kinase
LA62_RS07695	COG2197	response regulator
LA62_RS07705	COG2239	Acts as a magnesium transporter
LA62_RS07715	COG0300	oxidoreductase activity
LA62_RS07725	COG0656	L-ascorbic acid biosynthetic process
LA62_RS07740	COG1376	ErfK ybiS ycfS ynhG family protein
LA62_RS07755	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LA62_RS07760	COG0433	COG0433 Predicted ATPase
LA62_RS07775	COG0300	oxidoreductase activity
LA62_RS07790	COG1301	dicarboxylic acid transport
LA62_RS07800	COG0531	amino acid
LA62_RS07820	COG4424	Sulfotransferase
LA62_RS07825	COG3119	arylsulfatase activity
LA62_RS07860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LA62_RS07860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LA62_RS07895	COG2902	Dehydrogenase
LA62_RS07900	COG0824	Thioesterase
LA62_RS07915	COG0366	Alpha amylase catalytic
LA62_RS07950	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LA62_RS07970	COG1309	transcriptional regulator
LA62_RS07985	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LA62_RS08005	COG0740	serine-type endopeptidase activity
LA62_RS08010	COG0740	serine-type endopeptidase activity
LA62_RS08060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LA62_RS08070	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LA62_RS08070	COG0674	pyruvate-flavodoxin oxidoreductase activity
LA62_RS08075	COG1013	pyruvate-flavodoxin oxidoreductase activity
LA62_RS08085	COG1388	LysM domain
LA62_RS08115	COG0525	valine-tRNA ligase activity
LA62_RS08120	COG0285	dihydrofolate synthase activity
LA62_RS08135	COG1530	ribonuclease E activity
LA62_RS08165	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LA62_RS08185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LA62_RS08190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LA62_RS08195	COG0542	response to heat
LA62_RS08205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LA62_RS08215	COG0406	alpha-ribazole phosphatase activity
LA62_RS08220	COG2755	lipolytic protein G-D-S-L family
LA62_RS08240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA62_RS08275	COG2308	Evidence 4 Homologs of previously reported genes of
LA62_RS08285	COG1305	Transglutaminase-like
LA62_RS08315	COG3387	PFAM Glycoside hydrolase 15-related
LA62_RS08330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA62_RS08365	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LA62_RS08370	COG4208	sulfate ABC transporter
LA62_RS08430	COG0484	heat shock protein binding
LA62_RS08510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LA62_RS08525	COG0076	glutamate decarboxylase activity
LA62_RS08560	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS08610	COG0423	glycine-tRNA ligase activity
LA62_RS08615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LA62_RS08620	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LA62_RS08640	COG0358	DNA primase activity
LA62_RS08705	COG0745	RESPONSE REGULATOR receiver
LA62_RS08710	COG5002	protein histidine kinase activity
LA62_RS09070	COG3179	chitinase
LA62_RS09270	COG0488	(ABC) transporter
LA62_RS09295	COG1960	acyl-CoA dehydrogenase activity
LA62_RS09300	COG1335	isochorismatase
LA62_RS09310	COG0058	SHG alpha-glucan phosphorylase activity
LA62_RS09350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA62_RS09355	COG1960	acyl-CoA dehydrogenase activity
LA62_RS09360	COG0183	Belongs to the thiolase family
LA62_RS09380	COG1228	amidohydrolase
LA62_RS09410	COG0604	alcohol dehydrogenase
LA62_RS09410	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS09410	COG3321	synthase
LA62_RS09430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LA62_RS09460	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LA62_RS09490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA62_RS09530	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LA62_RS09535	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LA62_RS09595	COG0714	Associated with various cellular activities
LA62_RS09615	COG0557	exoribonuclease II activity
LA62_RS09625	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS09650	COG0174	glutamine synthetase
LA62_RS09655	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LA62_RS09685	COG2205	protein histidine kinase activity
LA62_RS09715	COG0174	glutamine synthetase
LA62_RS09725	COG0477	Major facilitator Superfamily
LA62_RS09735	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LA62_RS09755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LA62_RS09760	COG0321	lipoyl(octanoyl) transferase activity
LA62_RS09775	COG1872	DUF167
LA62_RS09795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LA62_RS09805	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LA62_RS09810	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LA62_RS09840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LA62_RS09885	COG2010	Cytochrome c
LA62_RS09890	COG1845	cytochrome c oxidase, subunit III
LA62_RS09895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LA62_RS09930	COG2226	methyltransferase
LA62_RS09955	COG0003	Pfam Anion-transporting ATPase
LA62_RS09965	COG0204	Acyl-transferase
LA62_RS09970	COG5650	phosphatidylinositol metabolic process
LA62_RS09980	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LA62_RS10005	COG0142	geranyltranstransferase activity
LA62_RS10045	COG0768	penicillin binding
LA62_RS10065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LA62_RS10075	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LA62_RS10090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LA62_RS10115	COG0640	Transcriptional regulator
LA62_RS10170	COG0154	amidase activity
LA62_RS10180	COG2957	Belongs to the agmatine deiminase family
LA62_RS10190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LA62_RS10200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LA62_RS10210	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS10240	COG2814	Major facilitator Superfamily
LA62_RS10315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS10320	COG2030	dehydratase
LA62_RS10340	COG1024	Enoyl-CoA hydratase
LA62_RS10355	COG1309	transcriptional regulator
LA62_RS10380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA62_RS10430	COG2072	flavoprotein involved in K transport
LA62_RS10445	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS10450	COG1960	acyl-CoA dehydrogenase activity
LA62_RS10470	COG1960	acyl-CoA dehydrogenase activity
LA62_RS10505	COG3621	Patatin-like phospholipase
LA62_RS10560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LA62_RS10590	COG1968	undecaprenyl-diphosphatase activity
LA62_RS10625	COG1218	3'(2'),5'-bisphosphate nucleotidase
LA62_RS10635	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS10660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA62_RS10670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA62_RS10670	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LA62_RS10685	COG2860	membrane
LA62_RS10695	COG1410	methionine synthase
LA62_RS10695	COG0646	methionine synthase
LA62_RS10700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LA62_RS10710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LA62_RS10745	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LA62_RS10750	COG1034	ATP synthesis coupled electron transport
LA62_RS10755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LA62_RS10760	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LA62_RS10840	COG0513	Belongs to the DEAD box helicase family
LA62_RS10880	COG0028	Belongs to the TPP enzyme family
LA62_RS10895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LA62_RS10900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LA62_RS10905	COG4122	O-methyltransferase activity
LA62_RS10935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LA62_RS10940	COG4521	taurine ABC transporter
LA62_RS10945	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LA62_RS10980	COG2378	regulation of single-species biofilm formation
LA62_RS10985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LA62_RS11020	COG0300	oxidoreductase activity
LA62_RS11075	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LA62_RS11085	COG0463	Glycosyl transferase, family 2
LA62_RS11090	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS11115	COG3321	synthase
LA62_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS11115	COG0604	alcohol dehydrogenase
LA62_RS11135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LA62_RS11145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LA62_RS11150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS11170	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LA62_RS11195	COG4842	Belongs to the WXG100 family
LA62_RS11225	COG0464	growth
LA62_RS11245	COG0583	DNA-binding transcription factor activity
LA62_RS11275	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LA62_RS11280	COG1169	isochorismate synthase
LA62_RS11285	COG0789	Transcriptional regulator
LA62_RS11290	COG1021	2,3-dihydroxybenzoate-AMP ligase
LA62_RS11320	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LA62_RS11345	COG0300	oxidoreductase activity
LA62_RS11345	COG3321	synthase
LA62_RS11345	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS11345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA62_RS11345	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS11360	COG1132	(ABC) transporter
LA62_RS11365	COG2375	cellular response to nickel ion
LA62_RS11365	COG1132	(ABC) transporter
LA62_RS11370	COG0477	Major facilitator Superfamily
LA62_RS11375	COG5285	phytanoyl-CoA dioxygenase
LA62_RS11385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LA62_RS11390	COG0456	acetyltransferase
LA62_RS11410	COG2837	iron assimilation
LA62_RS11420	COG2186	Transcriptional regulator
LA62_RS11425	COG2807	transmembrane transport
LA62_RS11435	COG2409	Drug exporters of the RND superfamily
LA62_RS11440	COG3629	intracellular signal transduction
LA62_RS11445	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS11485	COG0475	glutathione-regulated potassium exporter activity
LA62_RS11550	COG0237	dephospho-CoA kinase activity
LA62_RS11550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LA62_RS11735	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LA62_RS11740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LA62_RS11740	COG0072	phenylalanine-tRNA ligase activity
LA62_RS11750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LA62_RS11755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LA62_RS11760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LA62_RS11765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LA62_RS11770	COG1438	arginine binding
LA62_RS11775	COG0137	argininosuccinate synthase activity
LA62_RS11815	COG2835	tetraacyldisaccharide 4'-kinase activity
LA62_RS11820	COG1309	transcriptional regulator
LA62_RS11825	COG2094	Belongs to the DNA glycosylase MPG family
LA62_RS11850	COG0647	UMP catabolic process
LA62_RS11865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LA62_RS11885	COG0504	CTP synthase activity
LA62_RS11890	COG0494	nUDIX hydrolase
LA62_RS11910	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LA62_RS11925	COG1160	GTP binding
LA62_RS11935	COG1403	HNH endonuclease
LA62_RS12015	COG1053	succinate dehydrogenase
LA62_RS12015	COG3976	FMN-binding domain protein
LA62_RS12045	COG1960	acyl-CoA dehydrogenase activity
LA62_RS12105	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LA62_RS12105	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LA62_RS12120	COG1253	flavin adenine dinucleotide binding
LA62_RS12125	COG1253	flavin adenine dinucleotide binding
LA62_RS12135	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LA62_RS12190	COG0832	Belongs to the urease beta subunit family
LA62_RS12200	COG0830	nickel cation binding
LA62_RS12215	COG1252	NADH dehydrogenase
LA62_RS12225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS12260	COG0243	molybdopterin cofactor binding
LA62_RS12270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LA62_RS12285	COG1058	Belongs to the CinA family
LA62_RS12285	COG1546	Belongs to the CinA family
LA62_RS12295	COG4977	sequence-specific DNA binding
LA62_RS12300	COG1741	Belongs to the pirin family
LA62_RS12320	COG1968	undecaprenyl-diphosphatase activity
LA62_RS12325	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LA62_RS12350	COG0277	FAD linked oxidase domain protein
LA62_RS12360	COG1309	transcriptional regulator
LA62_RS12375	COG1116	anion transmembrane transporter activity
LA62_RS12380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LA62_RS12385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LA62_RS12410	COG4290	ribonuclease
LA62_RS12440	COG0791	NLP P60 protein
LA62_RS12440	COG3883	PFAM NLP P60 protein
LA62_RS12475	COG0477	Major facilitator Superfamily
LA62_RS12495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LA62_RS12500	COG0069	glutamate synthase activity
LA62_RS12500	COG0070	glutamate synthase
LA62_RS12500	COG0067	glutamate synthase
LA62_RS12530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LA62_RS12545	COG1960	acyl-CoA dehydrogenase activity
LA62_RS12560	COG0443	Heat shock 70 kDa protein
LA62_RS12565	COG0596	Alpha beta hydrolase
LA62_RS12585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LA62_RS12595	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LA62_RS12615	COG2890	protein-(glutamine-N5) methyltransferase activity
LA62_RS12685	COG1982	Orn Lys Arg decarboxylase major
LA62_RS12740	COG0028	Belongs to the TPP enzyme family
LA62_RS12750	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS12770	COG1309	transcriptional regulator
LA62_RS12775	COG2957	Belongs to the agmatine deiminase family
LA62_RS12780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA62_RS12795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LA62_RS12840	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LA62_RS12855	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LA62_RS12875	COG0640	Transcriptional regulator
LA62_RS12885	COG0798	PFAM Bile acid sodium symporter
LA62_RS12890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LA62_RS12895	COG0390	transport system, permease component
LA62_RS12915	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS12920	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA62_RS12950	COG0745	RESPONSE REGULATOR receiver
LA62_RS12955	COG2205	protein histidine kinase activity
LA62_RS12970	COG1917	Cupin 2, conserved barrel domain protein
LA62_RS12975	COG3707	response regulator
LA62_RS13015	COG3467	pyridoxamine 5'-phosphate
LA62_RS13020	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
LA62_RS13040	COG0640	Transcriptional regulator
LA62_RS13060	COG1309	transcriptional regulator
LA62_RS13065	COG2072	flavoprotein involved in K transport
LA62_RS13075	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS13080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LA62_RS13085	COG0561	phosphatase activity
LA62_RS13090	COG0673	inositol 2-dehydrogenase activity
LA62_RS13095	COG0738	Major facilitator superfamily
LA62_RS13180	COG1271	oxidase subunit
LA62_RS13185	COG1294	oxidase, subunit
LA62_RS13190	COG4988	ABC transporter
LA62_RS13195	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LA62_RS13220	COG1946	Acyl-CoA thioesterase
LA62_RS13265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LA62_RS13270	COG1846	Transcriptional regulator
LA62_RS13300	COG2072	flavoprotein involved in K transport
LA62_RS13305	COG0657	acetylesterase activity
LA62_RS13360	COG0483	inositol monophosphate 1-phosphatase activity
LA62_RS13370	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LA62_RS13375	COG0131	Imidazoleglycerol-phosphate dehydratase
LA62_RS13380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LA62_RS13405	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LA62_RS13420	COG1309	transcriptional regulator
LA62_RS13440	COG0583	DNA-binding transcription factor activity
LA62_RS13445	COG0579	oxidoreductase
LA62_RS13485	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LA62_RS13485	COG2755	lipolytic protein G-D-S-L family
LA62_RS13540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LA62_RS13560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LA62_RS13565	COG2814	Major facilitator Superfamily
LA62_RS13570	COG0583	DNA-binding transcription factor activity
LA62_RS13620	COG2239	Acts as a magnesium transporter
LA62_RS13650	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LA62_RS13660	COG2304	oxidoreductase activity
LA62_RS13670	COG0714	Associated with various cellular activities
LA62_RS13680	COG3883	PFAM NLP P60 protein
LA62_RS13680	COG0791	NLP P60 protein
LA62_RS13690	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LA62_RS13695	COG1309	transcriptional regulator
LA62_RS13720	COG0488	(ABC) transporter
LA62_RS13735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LA62_RS13750	COG0456	acetyltransferase
LA62_RS13760	COG2151	metal-sulfur cluster biosynthetic enzyme
LA62_RS13775	COG0396	ATPase activity
LA62_RS13800	COG1131	(ABC) transporter
LA62_RS13840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LA62_RS13860	COG0583	DNA-binding transcription factor activity
LA62_RS13865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA62_RS13935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LA62_RS13995	COG0531	amino acid
LA62_RS14050	COG2011	ABC-type metal ion transport system permease component
LA62_RS14055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LA62_RS14075	COG0477	Major facilitator Superfamily
LA62_RS14110	COG0657	acetylesterase activity
LA62_RS14115	COG1953	Uracil, thiamine, allantoin
LA62_RS14125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LA62_RS14130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA62_RS14140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LA62_RS14150	COG1758	RNA polymerase activity
LA62_RS14170	COG0284	orotidine-5'-phosphate decarboxylase activity
LA62_RS14175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LA62_RS14180	COG0505	Belongs to the CarA family
LA62_RS14200	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LA62_RS14220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LA62_RS14230	COG0006	proline dipeptidase activity
LA62_RS14245	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LA62_RS14250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LA62_RS14265	COG4106	trans-aconitate 2-methyltransferase activity
LA62_RS14280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LA62_RS14295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LA62_RS14345	COG0701	Predicted permease
LA62_RS14370	COG2272	Belongs to the type-B carboxylesterase lipase family
LA62_RS14410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LA62_RS14420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LA62_RS14430	COG0747	negative chemotaxis
LA62_RS14435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LA62_RS14450	COG2255	four-way junction helicase activity
LA62_RS14460	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LA62_RS14495	COG1946	Acyl-CoA thioesterase
LA62_RS14500	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LA62_RS14510	COG0438	transferase activity, transferring glycosyl groups
LA62_RS14550	COG4762	Protein conserved in bacteria
LA62_RS14605	COG1309	transcriptional regulator
LA62_RS14630	COG3878	Protein conserved in bacteria
LA62_RS14675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA62_RS14690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LA62_RS14690	COG2080	2 iron, 2 sulfur cluster binding
LA62_RS14705	COG0402	S-adenosylhomocysteine deaminase activity
LA62_RS14725	COG2233	PERMEase
LA62_RS14745	COG1953	Uracil, thiamine, allantoin
LA62_RS14755	COG1301	dicarboxylic acid transport
LA62_RS14765	COG4266	Belongs to the allantoicase family
LA62_RS14795	COG2267	carboxylic ester hydrolase activity
LA62_RS14800	COG1960	acyl-CoA dehydrogenase activity
LA62_RS14805	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS14820	COG0183	Belongs to the thiolase family
LA62_RS14835	COG0501	Belongs to the peptidase M48B family
LA62_RS14850	COG0477	Major facilitator Superfamily
LA62_RS14905	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA62_RS14915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LA62_RS14955	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LA62_RS14980	COG3253	May function as heme-dependent peroxidase
LA62_RS14985	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LA62_RS15000	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LA62_RS15015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LA62_RS15020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LA62_RS15025	COG0531	amino acid
LA62_RS15030	COG0569	domain protein
LA62_RS15060	COG0702	epimerase
LA62_RS15075	COG0756	dUTP diphosphatase activity
LA62_RS15120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LA62_RS15130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LA62_RS15170	COG3220	belongs to the UPF0276 family
LA62_RS15245	COG1388	LysM domain
LA62_RS15260	COG1960	acyl-CoA dehydrogenase activity
LA62_RS15270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LA62_RS15290	COG1196	nuclear chromosome segregation
LA62_RS15310	COG1126	abc transporter atp-binding protein
LA62_RS15315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LA62_RS15320	COG0765	amino acid transport
LA62_RS15325	COG0765	amino acid transport
LA62_RS15375	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
LA62_RS15380	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
LA62_RS15395	COG1842	Phage shock protein A
LA62_RS15400	COG1396	sequence-specific DNA binding
LA62_RS15410	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS15420	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LA62_RS15475	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LA62_RS15480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LA62_RS15495	COG3214	Protein conserved in bacteria
LA62_RS15535	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LA62_RS15545	COG0659	secondary active sulfate transmembrane transporter activity
LA62_RS15555	COG0686	Belongs to the AlaDH PNT family
LA62_RS15570	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS15640	COG2977	Belongs to the P-Pant transferase superfamily
LA62_RS15645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LA62_RS15665	COG1960	acyl-CoA dehydrogenase activity
LA62_RS15670	COG1960	acyl-CoA dehydrogenase activity
LA62_RS15675	COG1024	Enoyl-CoA hydratase
LA62_RS15700	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LA62_RS15725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LA62_RS15725	COG1017	nitric oxide dioxygenase activity
LA62_RS15730	COG1959	2 iron, 2 sulfur cluster binding
LA62_RS15775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LA62_RS15775	COG1648	precorrin-2 dehydrogenase activity
LA62_RS15800	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS15800	COG0604	alcohol dehydrogenase
LA62_RS15800	COG3321	synthase
LA62_RS15860	COG0579	oxidoreductase
LA62_RS15880	COG1492	cobalamin metabolic process
LA62_RS15890	COG1376	ErfK ybiS ycfS ynhG family protein
LA62_RS15915	COG0750	zinc metalloprotease
LA62_RS15940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LA62_RS16005	COG0528	UMP kinase activity
LA62_RS16010	COG3973	AAA domain
LA62_RS16025	COG2723	6-phospho-beta-galactosidase activity
LA62_RS16060	COG1309	transcriptional regulator
LA62_RS16100	COG0583	DNA-binding transcription factor activity
LA62_RS16130	COG0792	nuclease activity
LA62_RS16190	COG0336	Belongs to the RNA methyltransferase TrmD family
LA62_RS16230	COG1686	Belongs to the peptidase S11 family
LA62_RS16250	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LA62_RS16270	COG1304	FMN binding
LA62_RS16320	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LA62_RS16325	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LA62_RS16345	COG0571	ribonuclease III activity
LA62_RS16355	COG3599	regulation of cell shape
LA62_RS16395	COG0742	ribosomal rna small subunit methyltransferase
LA62_RS16400	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LA62_RS16415	COG0657	acetylesterase activity
LA62_RS16420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS16440	COG2124	cytochrome p450
LA62_RS16455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LA62_RS16460	COG1461	Dihydroxyacetone kinase
LA62_RS16470	COG1024	Enoyl-CoA hydratase
LA62_RS16495	COG1181	Belongs to the D-alanine--D-alanine ligase family
LA62_RS16500	COG0626	cystathionine gamma-synthase activity
LA62_RS16505	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LA62_RS16570	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA62_RS16585	COG2271	Major facilitator Superfamily
LA62_RS16615	COG0583	DNA-binding transcription factor activity
LA62_RS16625	COG0778	Nitroreductase
LA62_RS16640	COG1309	transcriptional regulator
LA62_RS16645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA62_RS16650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA62_RS16655	COG2124	cytochrome p450
LA62_RS16685	COG0440	acetolactate synthase activity
LA62_RS16700	COG1748	Saccharopine dehydrogenase
LA62_RS16705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LA62_RS16725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA62_RS16745	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LA62_RS16755	COG2272	Belongs to the type-B carboxylesterase lipase family
LA62_RS16770	COG0745	RESPONSE REGULATOR receiver
LA62_RS16775	COG2205	protein histidine kinase activity
LA62_RS16800	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LA62_RS16830	COG1024	Enoyl-CoA hydratase
LA62_RS16835	COG0778	Nitroreductase
LA62_RS16845	COG2252	PERMEase
LA62_RS16885	COG2197	response regulator
LA62_RS16890	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LA62_RS16900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LA62_RS16920	COG1522	sequence-specific DNA binding
LA62_RS16925	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LA62_RS16940	COG1309	transcriptional regulator
LA62_RS16970	COG0110	maltose O-acetyltransferase activity
LA62_RS16975	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LA62_RS17000	COG1119	ATPase activity
LA62_RS17010	COG2364	Membrane
LA62_RS17015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LA62_RS17030	COG4607	ABC-type enterochelin transport system periplasmic component
LA62_RS17080	COG1064	alcohol dehydrogenase
LA62_RS17100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LA62_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS17165	COG0477	Major facilitator Superfamily
LA62_RS17185	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS17215	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS17240	COG1335	isochorismatase
LA62_RS17250	COG2855	membrane
LA62_RS17260	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS17275	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS17285	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS17290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LA62_RS17350	COG2272	Belongs to the type-B carboxylesterase lipase family
LA62_RS17365	COG0183	Belongs to the thiolase family
LA62_RS17400	COG1309	transcriptional regulator
LA62_RS17425	COG0789	Transcriptional regulator
LA62_RS17435	COG0028	Belongs to the TPP enzyme family
LA62_RS17455	COG2177	Part of the ABC transporter FtsEX involved in
LA62_RS17460	COG2884	Cell division ATP-binding protein ftsE
LA62_RS17470	COG0668	transmembrane transport
LA62_RS17510	COG0483	inositol monophosphate 1-phosphatase activity
LA62_RS17515	COG1960	acyl-CoA dehydrogenase activity
LA62_RS17520	COG1960	acyl-CoA dehydrogenase activity
LA62_RS17535	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS17545	COG0542	response to heat
LA62_RS17590	COG3480	Lon protease (S16) C-terminal proteolytic domain
LA62_RS17595	COG3011	Protein conserved in bacteria
LA62_RS17610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA62_RS17615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA62_RS17625	COG0300	oxidoreductase activity
LA62_RS17630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA62_RS17665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LA62_RS17665	COG0475	glutathione-regulated potassium exporter activity
LA62_RS17680	COG0596	Alpha beta hydrolase
LA62_RS17695	COG0745	RESPONSE REGULATOR receiver
LA62_RS17705	COG2146	nitrite reductase [NAD(P)H] activity
LA62_RS17705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LA62_RS17710	COG2223	nitrite transmembrane transporter activity
LA62_RS17750	COG0513	Belongs to the DEAD box helicase family
LA62_RS17765	COG0406	alpha-ribazole phosphatase activity
LA62_RS17785	COG1597	lipid kinase activity
LA62_RS17800	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LA62_RS17810	COG1595	DNA-templated transcription, initiation
LA62_RS17815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LA62_RS17820	COG2135	peptidase activity
LA62_RS17825	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LA62_RS17830	COG1162	GTPase activity
LA62_RS17865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LA62_RS17960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LA62_RS17965	COG0604	alcohol dehydrogenase
LA62_RS17965	COG3321	synthase
LA62_RS17970	COG3321	synthase
LA62_RS17970	COG0604	alcohol dehydrogenase
LA62_RS17975	COG1960	acyl-CoA dehydrogenase activity
LA62_RS17985	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS17990	COG0653	protein targeting
LA62_RS18000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LA62_RS18005	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LA62_RS18015	COG1309	transcriptional regulator
LA62_RS18030	COG5401	PFAM Sporulation and spore germination
LA62_RS18035	COG5002	protein histidine kinase activity
LA62_RS18045	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS18050	COG1285	pathogenesis
LA62_RS18080	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LA62_RS18085	COG0531	amino acid
LA62_RS18095	COG1482	cell wall glycoprotein biosynthetic process
LA62_RS18125	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LA62_RS18130	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LA62_RS18130	COG0778	Nitroreductase
LA62_RS18145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LA62_RS18160	COG1316	TRANSCRIPTIONal
LA62_RS18180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LA62_RS18190	COG2175	clavaminate synthase activity
LA62_RS18215	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LA62_RS18215	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LA62_RS18225	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS18240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA62_RS18260	COG3265	gluconokinase activity
LA62_RS18265	COG1960	acyl-CoA dehydrogenase activity
LA62_RS18280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS18300	COG4770	biotin carboxylase activity
LA62_RS18310	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LA62_RS18330	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS18335	COG1309	transcriptional regulator
LA62_RS18340	COG1201	RNA secondary structure unwinding
LA62_RS18355	COG0564	pseudouridine synthase activity
LA62_RS18375	COG1473	amidohydrolase
LA62_RS18375	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LA62_RS18390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LA62_RS18405	COG0791	NLP P60 protein
LA62_RS18405	COG3883	PFAM NLP P60 protein
LA62_RS18450	COG2009	succinate dehydrogenase
LA62_RS18465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LA62_RS18470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LA62_RS18475	COG1595	DNA-templated transcription, initiation
LA62_RS18490	COG1686	Belongs to the peptidase S11 family
LA62_RS18505	COG0708	Exodeoxyribonuclease III
LA62_RS18565	COG1733	regulation of RNA biosynthetic process
LA62_RS18570	COG2910	NAD(P)H-binding
LA62_RS18575	COG1131	(ABC) transporter
LA62_RS18575	COG0842	Transport permease protein
LA62_RS18575	COG1716	ATPase activity
LA62_RS18580	COG1357	PFAM Pentapeptide repeats (8 copies)
LA62_RS18595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LA62_RS18600	COG0587	DNA-directed DNA polymerase activity
LA62_RS18605	COG1073	alpha beta
LA62_RS18610	COG1309	transcriptional regulator
LA62_RS18675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LA62_RS18675	COG0519	Catalyzes the synthesis of GMP from XMP
LA62_RS18685	COG0516	GMP reductase activity
LA62_RS18745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LA62_RS18760	COG0456	acetyltransferase
LA62_RS18780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LA62_RS18785	COG0076	glutamate decarboxylase activity
LA62_RS18795	COG2267	carboxylic ester hydrolase activity
LA62_RS18800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LA62_RS18825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS18835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LA62_RS18840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LA62_RS18875	COG1404	Belongs to the peptidase S8 family
LA62_RS18905	COG2267	carboxylic ester hydrolase activity
LA62_RS18960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LA62_RS18965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA62_RS18975	COG2268	Band 7 protein
LA62_RS18985	COG1088	dTDP-glucose 4,6-dehydratase activity
LA62_RS18990	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LA62_RS19035	COG0616	signal peptide processing
LA62_RS19050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS19070	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LA62_RS19080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LA62_RS19090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LA62_RS19105	COG2272	Belongs to the type-B carboxylesterase lipase family
LA62_RS19130	COG0477	Major facilitator Superfamily
LA62_RS19145	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LA62_RS19185	COG0088	Forms part of the polypeptide exit tunnel
LA62_RS19190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LA62_RS19195	COG0051	transcription antitermination factor activity, RNA binding
LA62_RS19230	COG0531	amino acid
LA62_RS19260	COG0535	radical SAM domain protein
LA62_RS19285	COG1834	amidinotransferase
LA62_RS19290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LA62_RS19295	COG0531	amino acid
LA62_RS19340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LA62_RS19345	COG1309	transcriptional regulator
LA62_RS19370	COG1024	Enoyl-CoA hydratase
LA62_RS19385	COG1960	acyl-CoA dehydrogenase activity
LA62_RS19415	COG1113	amino acid transport
LA62_RS19430	COG0085	RNA polymerase activity
LA62_RS19435	COG0243	molybdopterin cofactor binding
LA62_RS19490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LA62_RS19505	COG0277	FAD linked oxidase domain protein
LA62_RS19525	COG4941	Belongs to the sigma-70 factor family
LA62_RS19560	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LA62_RS19600	COG0783	Belongs to the Dps family
LA62_RS19605	COG0693	protein deglycase activity
LA62_RS19650	COG1404	Belongs to the peptidase S8 family
LA62_RS19670	COG1280	lysine exporter protein (LysE YggA)
LA62_RS19740	COG0501	Belongs to the peptidase M48B family
LA62_RS19745	COG0142	geranyltranstransferase activity
LA62_RS19750	COG0644	oxidoreductase
LA62_RS19760	COG0438	transferase activity, transferring glycosyl groups
LA62_RS19780	COG4948	Mandelate Racemase Muconate Lactonizing
LA62_RS19805	COG3706	GGDEF domain
LA62_RS19820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LA62_RS19830	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LA62_RS19835	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS19840	COG4221	oxidoreductase activity
LA62_RS19885	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LA62_RS19890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LA62_RS19900	COG0542	response to heat
LA62_RS19930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LA62_RS19975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LA62_RS19980	COG1333	cytochrome c biogenesis protein
LA62_RS19985	COG0785	Cytochrome C biogenesis protein
LA62_RS19995	COG0406	alpha-ribazole phosphatase activity
LA62_RS20015	COG3590	peptidase
LA62_RS20065	COG1587	Uroporphyrinogen-III synthase
LA62_RS20065	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LA62_RS20090	COG2030	dehydratase
LA62_RS20115	COG2070	2-Nitropropane dioxygenase
LA62_RS20135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LA62_RS20140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LA62_RS20245	COG1309	transcriptional regulator
LA62_RS20255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA62_RS20305	COG2072	flavoprotein involved in K transport
LA62_RS20320	COG2072	flavoprotein involved in K transport
LA62_RS20325	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS20330	COG0657	acetylesterase activity
LA62_RS20335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA62_RS20345	COG0745	RESPONSE REGULATOR receiver
LA62_RS20350	COG5002	protein histidine kinase activity
LA62_RS20360	COG2072	flavoprotein involved in K transport
LA62_RS20375	COG0300	oxidoreductase activity
LA62_RS20430	COG2814	Major facilitator Superfamily
LA62_RS20525	COG2733	membrane
LA62_RS20535	COG2326	polyphosphate kinase activity
LA62_RS20540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LA62_RS20575	COG2224	Isocitrate lyase
LA62_RS20620	COG2226	methyltransferase
LA62_RS20670	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LA62_RS20705	COG0667	Aldo Keto reductase
LA62_RS20725	COG4552	Acetyltransferase involved in intracellular survival and related
LA62_RS20730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS20755	COG1505	serine-type exopeptidase activity
LA62_RS20775	COG1073	alpha beta
LA62_RS20780	COG2326	polyphosphate kinase activity
LA62_RS20795	COG2223	nitrite transmembrane transporter activity
LA62_RS20800	COG0640	Transcriptional regulator
LA62_RS20830	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LA62_RS20850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LA62_RS20875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA62_RS20880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA62_RS20885	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS20895	COG1960	acyl-CoA dehydrogenase activity
LA62_RS20900	COG1960	acyl-CoA dehydrogenase activity
LA62_RS20905	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS20915	COG2070	2-Nitropropane dioxygenase
LA62_RS20925	COG1024	Enoyl-CoA hydratase
LA62_RS20930	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LA62_RS20935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS20970	COG4638	Rieske (2fe-2S)
LA62_RS21010	COG0175	sulfate reduction
LA62_RS21080	COG2814	Major facilitator Superfamily
LA62_RS21090	COG0351	phosphomethylpyrimidine kinase
LA62_RS21100	COG1252	NADH dehydrogenase
LA62_RS21110	COG1309	transcriptional regulator
LA62_RS21120	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS21155	COG0494	nUDIX hydrolase
LA62_RS21165	COG2234	aminopeptidase activity
LA62_RS21170	COG2234	aminopeptidase activity
LA62_RS21180	COG1131	(ABC) transporter
LA62_RS21185	COG2022	thiamine diphosphate biosynthetic process
LA62_RS21220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LA62_RS21225	COG0515	serine threonine protein kinase
LA62_RS21230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LA62_RS21260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LA62_RS21265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS21270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS21275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS21285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LA62_RS21290	COG1126	abc transporter atp-binding protein
LA62_RS21330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LA62_RS21360	COG1994	Peptidase M50
LA62_RS21380	COG0586	Pfam SNARE associated Golgi protein
LA62_RS21410	COG4221	oxidoreductase activity
LA62_RS21430	COG0542	response to heat
LA62_RS21455	COG0789	Transcriptional regulator
LA62_RS21460	COG0484	heat shock protein binding
LA62_RS21465	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LA62_RS21535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LA62_RS21535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LA62_RS21575	COG2181	nitrate reductase activity
LA62_RS21575	COG0247	lactate metabolic process
LA62_RS21585	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LA62_RS21625	COG3345	alpha-galactosidase
LA62_RS21630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LA62_RS21635	COG1305	Transglutaminase-like
LA62_RS21650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LA62_RS21720	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS21730	COG0454	-acetyltransferase
LA62_RS21785	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS21790	COG1960	acyl-CoA dehydrogenase activity
LA62_RS21805	COG3268	Saccharopine dehydrogenase
LA62_RS21810	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS21815	COG3285	dna ligase
LA62_RS21815	COG1793	dna ligase
LA62_RS21820	COG0494	nUDIX hydrolase
LA62_RS21830	COG2902	Dehydrogenase
LA62_RS21835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LA62_RS21850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA62_RS21870	COG1309	transcriptional regulator
LA62_RS21880	COG0778	Nitroreductase
LA62_RS21885	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA62_RS21910	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA62_RS21915	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS21920	COG1396	sequence-specific DNA binding
LA62_RS21940	COG2267	carboxylic ester hydrolase activity
LA62_RS21945	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LA62_RS21960	COG4638	Rieske (2fe-2S)
LA62_RS21965	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS21965	COG0604	alcohol dehydrogenase
LA62_RS21965	COG3321	synthase
LA62_RS21970	COG3384	dioxygenase
LA62_RS21975	COG3971	2-oxopent-4-enoate hydratase activity
LA62_RS21990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LA62_RS21995	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS22030	COG1309	transcriptional regulator
LA62_RS22055	COG1309	transcriptional regulator
LA62_RS22060	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LA62_RS22075	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LA62_RS22080	COG1984	allophanate hydrolase subunit 2
LA62_RS22145	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LA62_RS22150	COG1802	Transcriptional regulator
LA62_RS22180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LA62_RS22190	COG0473	3-isopropylmalate dehydrogenase activity
LA62_RS22205	COG1053	succinate dehydrogenase
LA62_RS22225	COG0640	Transcriptional regulator
LA62_RS22275	COG2318	DinB family
LA62_RS22280	COG1960	acyl-CoA dehydrogenase activity
LA62_RS22295	COG1660	Displays ATPase and GTPase activities
LA62_RS22305	COG0183	Belongs to the thiolase family
LA62_RS22310	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS22315	COG2030	dehydratase
LA62_RS22330	COG0659	secondary active sulfate transmembrane transporter activity
LA62_RS22335	COG1309	transcriptional regulator
LA62_RS22340	COG0861	Integral membrane protein TerC family
LA62_RS22365	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS22380	COG1472	Belongs to the glycosyl hydrolase 3 family
LA62_RS22385	COG4941	Belongs to the sigma-70 factor family
LA62_RS22450	COG4981	capsule polysaccharide biosynthetic process
LA62_RS22490	COG0438	transferase activity, transferring glycosyl groups
LA62_RS22535	COG1250	3-hydroxyacyl-CoA dehydrogenase
LA62_RS22580	COG2197	response regulator
LA62_RS22585	COG3850	Histidine kinase
LA62_RS22605	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LA62_RS22635	COG2409	Drug exporters of the RND superfamily
LA62_RS22680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA62_RS22690	COG2197	response regulator
LA62_RS22720	COG2353	YceI-like domain
LA62_RS22740	COG2409	Drug exporters of the RND superfamily
LA62_RS22755	COG4552	Acetyltransferase involved in intracellular survival and related
LA62_RS22760	COG1832	CoA-binding protein
LA62_RS22775	COG3590	peptidase
LA62_RS22780	COG1376	ErfK ybiS ycfS ynhG family protein
LA62_RS22785	COG1960	acyl-CoA dehydrogenase activity
LA62_RS22795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA62_RS22805	COG1937	Protein conserved in bacteria
LA62_RS22830	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS22835	COG4122	O-methyltransferase activity
LA62_RS22850	COG2267	carboxylic ester hydrolase activity
LA62_RS22880	COG1704	LemA family
LA62_RS22890	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS22945	COG1024	Enoyl-CoA hydratase
LA62_RS22950	COG1802	Transcriptional regulator
LA62_RS22960	COG2267	carboxylic ester hydrolase activity
LA62_RS22965	COG1309	transcriptional regulator
LA62_RS22995	COG0435	Glutathione S-transferase
LA62_RS23035	COG1024	Enoyl-CoA hydratase
LA62_RS23045	COG2211	Major facilitator Superfamily
LA62_RS23050	COG2365	Tyrosine phosphatase family
LA62_RS23100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA62_RS23115	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS23120	COG1012	belongs to the aldehyde dehydrogenase family
LA62_RS23135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LA62_RS23140	COG1960	acyl-CoA dehydrogenase activity
LA62_RS23145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LA62_RS23160	COG2226	methyltransferase
LA62_RS23175	COG3800	Transcriptional regulator
LA62_RS23175	COG1396	sequence-specific DNA binding
LA62_RS23185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LA62_RS23225	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS23285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LA62_RS23295	COG0129	dihydroxy-acid dehydratase activity
LA62_RS23315	COG2186	Transcriptional regulator
LA62_RS23345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LA62_RS23350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LA62_RS23360	COG0723	plastoquinol--plastocyanin reductase activity
LA62_RS23380	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS23420	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS23435	COG0318	PFAM AMP-dependent synthetase and ligase
LA62_RS23440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LA62_RS23445	COG1136	(ABC) transporter
LA62_RS23455	COG1104	cysteine desulfurase activity
LA62_RS23515	COG1309	transcriptional regulator
LA62_RS23525	COG1819	glycosyl
LA62_RS23570	COG1819	glycosyl
LA62_RS23680	COG3263	regulation of cellular component size
LA62_RS23760	COG1595	DNA-templated transcription, initiation
LA62_RS23770	COG0783	Belongs to the Dps family
LA62_RS23810	COG1252	NADH dehydrogenase
LA62_RS23830	COG1937	Protein conserved in bacteria
LA62_RS23855	COG1403	HNH endonuclease
LA62_RS23930	COG2140	Oxalate decarboxylase
LA62_RS23955	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LA62_RS23975	COG1376	ErfK ybiS ycfS ynhG family protein
LA62_RS23995	COG2030	dehydratase
LA62_RS24000	COG0488	(ABC) transporter
LA62_RS24005	COG3757	hydrolase, family 25
LA62_RS24070	COG0583	DNA-binding transcription factor activity
LA62_RS24080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA62_RS24095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LA62_RS24100	COG3757	hydrolase, family 25
LA62_RS24305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LA62_RS24335	COG0745	RESPONSE REGULATOR receiver
LA62_RS24340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LA62_RS24400	COG0640	Transcriptional regulator
LA62_RS24405	COG0640	Transcriptional regulator
LA62_RS24410	COG0798	PFAM Bile acid sodium symporter
LA62_RS24415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LA62_RS24420	COG0446	pyridine nucleotide-disulphide oxidoreductase
LA62_RS24430	COG0717	Belongs to the dCTP deaminase family
LA62_RS24470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LA62_RS24495	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LA62_RS24505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LA62_RS24540	COG0454	-acetyltransferase
LA62_RS24585	COG0629	single-stranded DNA binding
LA62_RS24600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LA62_RS24630	COG1260	myo-inositol-1-phosphate synthase
LA62_RS24640	COG1113	amino acid transport
LA62_RS24655	COG1309	transcriptional regulator
LA62_RS24660	COG1028	Short-chain dehydrogenase reductase Sdr
LA62_RS24675	COG0508	dehydrogenase complex catalyzes the overall conversion of
LA62_RS24680	COG0022	dehydrogenase e1 component
LA62_RS24695	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
LA62_RS24700	COG2311	Membrane
LA62_RS24765	COG0617	tRNA 3'-terminal CCA addition
LA62_RS24785	COG1595	DNA-templated transcription, initiation
LA62_RS24805	COG0860	N-Acetylmuramoyl-L-alanine amidase
LA62_RS24805	COG3409	Peptidoglycan-binding domain 1 protein
LA62_RS24815	COG2124	cytochrome p450
LA62_RS24825	COG1309	transcriptional regulator
LA62_RS24845	COG1192	Involved in chromosome partitioning
LA62_RS24850	COG0357	Ribosomal RNA small subunit methyltransferase G
LA62_RS24860	COG0706	membrane insertase activity
LA62_RS24930	COG2814	Major facilitator Superfamily
LA62_RS25015	COG0765	amino acid transport
LA62_RS25095	COG1902	pentaerythritol trinitrate reductase activity
LA62_RS25195	COG0567	Dehydrogenase, E1 component
LA62_RS25195	COG0508	dehydrogenase complex catalyzes the overall conversion of
LA62_RS25465	COG1403	HNH endonuclease
LA62_RS25530	COG1254	Belongs to the acylphosphatase family
LA62_RS25605	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LA62_RS25655	COG1414	Transcriptional regulator
LA62_RS25815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane