locus-tag	class	description
G6N59_RS00030	COG1914	H( )-stimulated, divalent metal cation uptake system
G6N59_RS00050	COG2239	Acts as a magnesium transporter
G6N59_RS00065	COG1285	pathogenesis
G6N59_RS00080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G6N59_RS00095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N59_RS00170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6N59_RS00175	COG0187	DNA topoisomerase II activity
G6N59_RS00225	COG1396	sequence-specific DNA binding
G6N59_RS00230	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
G6N59_RS00295	COG5651	PPE family
G6N59_RS00490	COG3328	transposase activity
G6N59_RS00580	COG1674	ftsk spoiiie
G6N59_RS00700	COG1481	regulation of sporulation
G6N59_RS00725	COG1061	Type III restriction enzyme res subunit
G6N59_RS00735	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N59_RS00785	COG3328	transposase activity
G6N59_RS00815	COG5651	PPE family
G6N59_RS00820	COG1252	NADH dehydrogenase
G6N59_RS00840	COG0412	Dienelactone hydrolase
G6N59_RS00845	COG1309	transcriptional regulator
G6N59_RS00885	COG4762	Protein conserved in bacteria
G6N59_RS00895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G6N59_RS00905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G6N59_RS00910	COG1560	Kdo2-lipid A biosynthetic process
G6N59_RS00915	COG0438	transferase activity, transferring glycosyl groups
G6N59_RS00930	COG1946	Acyl-CoA thioesterase
G6N59_RS00935	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G6N59_RS00945	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N59_RS01000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N59_RS01005	COG0747	negative chemotaxis
G6N59_RS01015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6N59_RS01050	COG4221	oxidoreductase activity
G6N59_RS01080	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G6N59_RS01085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G6N59_RS01095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N59_RS01100	COG0124	histidyl-tRNA synthetase
G6N59_RS01110	COG0753	catalase activity
G6N59_RS01115	COG1490	D-aminoacyl-tRNA deacylase activity
G6N59_RS01160	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N59_RS01195	COG3707	response regulator
G6N59_RS01205	COG1309	transcriptional regulator
G6N59_RS01215	COG2072	flavoprotein involved in K transport
G6N59_RS01235	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N59_RS01260	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G6N59_RS01265	COG2072	flavoprotein involved in K transport
G6N59_RS01275	COG0183	Belongs to the thiolase family
G6N59_RS01280	COG1733	regulation of RNA biosynthetic process
G6N59_RS01330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6N59_RS01335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G6N59_RS01345	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6N59_RS01360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G6N59_RS01370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G6N59_RS01380	COG0006	proline dipeptidase activity
G6N59_RS01385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G6N59_RS01390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G6N59_RS01400	COG0243	molybdopterin cofactor binding
G6N59_RS01410	COG2188	Transcriptional regulator
G6N59_RS01435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G6N59_RS01440	COG0154	amidase activity
G6N59_RS01475	COG0477	Major facilitator Superfamily
G6N59_RS01480	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G6N59_RS01500	COG0505	Belongs to the CarA family
G6N59_RS01505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G6N59_RS01510	COG0284	orotidine-5'-phosphate decarboxylase activity
G6N59_RS01535	COG1758	RNA polymerase activity
G6N59_RS01550	COG2376	Dihydroxyacetone kinase
G6N59_RS01555	COG2072	flavoprotein involved in K transport
G6N59_RS01575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G6N59_RS01635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N59_RS01635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N59_RS01640	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G6N59_RS01660	COG1365	unkown
G6N59_RS01665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G6N59_RS01670	COG0322	excinuclease ABC activity
G6N59_RS01675	COG1660	Displays ATPase and GTPase activities
G6N59_RS01685	COG1481	regulation of sporulation
G6N59_RS01690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G6N59_RS01695	COG0126	phosphoglycerate kinase activity
G6N59_RS01700	COG0149	triose-phosphate isomerase activity
G6N59_RS01720	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G6N59_RS01775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6N59_RS01785	COG0109	protoheme IX farnesyltransferase activity
G6N59_RS01805	COG3842	ATPase activity
G6N59_RS01810	COG0395	ABC-type sugar transport system, permease component
G6N59_RS01825	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS01835	COG0434	BtpA family
G6N59_RS01840	COG0483	inositol monophosphate 1-phosphatase activity
G6N59_RS01845	COG1349	DNA-binding transcription factor activity
G6N59_RS01860	COG1131	(ABC) transporter
G6N59_RS01885	COG0396	ATPase activity
G6N59_RS01900	COG2151	metal-sulfur cluster biosynthetic enzyme
G6N59_RS01915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N59_RS01925	COG0488	(ABC) transporter
G6N59_RS01940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N59_RS01945	COG0531	amino acid
G6N59_RS01950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G6N59_RS01955	COG1396	sequence-specific DNA binding
G6N59_RS01965	COG1309	transcriptional regulator
G6N59_RS01970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6N59_RS01980	COG0791	NLP P60 protein
G6N59_RS01980	COG3883	PFAM NLP P60 protein
G6N59_RS01990	COG0714	Associated with various cellular activities
G6N59_RS02005	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6N59_RS02065	COG3321	synthase
G6N59_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS02065	COG0604	alcohol dehydrogenase
G6N59_RS02115	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G6N59_RS02120	COG1051	belongs to the nudix hydrolase family
G6N59_RS02125	COG1051	belongs to the nudix hydrolase family
G6N59_RS02135	COG2501	S4 domain
G6N59_RS02145	COG0252	asparaginase activity
G6N59_RS02150	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G6N59_RS02175	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N59_RS02210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N59_RS02225	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N59_RS02265	COG0596	Alpha beta hydrolase
G6N59_RS02270	COG2957	Belongs to the agmatine deiminase family
G6N59_RS02275	COG1309	transcriptional regulator
G6N59_RS02305	COG1063	alcohol dehydrogenase
G6N59_RS02350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS02355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS02360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS02365	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS02370	COG1309	transcriptional regulator
G6N59_RS02380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS02415	COG1309	transcriptional regulator
G6N59_RS02420	COG1063	alcohol dehydrogenase
G6N59_RS02450	COG2814	Major facilitator Superfamily
G6N59_RS02495	COG1302	Protein conserved in bacteria
G6N59_RS02650	COG3835	regulator
G6N59_RS02665	COG0277	FAD linked oxidase domain protein
G6N59_RS02690	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
G6N59_RS02695	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
G6N59_RS02750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS02765	COG1126	abc transporter atp-binding protein
G6N59_RS02770	COG0765	amino acid transport
G6N59_RS02775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS02820	COG1902	pentaerythritol trinitrate reductase activity
G6N59_RS02825	COG3328	transposase activity
G6N59_RS02835	COG0492	ferredoxin-NADP+ reductase activity
G6N59_RS02840	COG3527	Alpha-acetolactate decarboxylase
G6N59_RS02845	COG0028	Belongs to the TPP enzyme family
G6N59_RS02860	COG0598	Magnesium transport protein CorA
G6N59_RS02910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N59_RS02910	COG0574	Belongs to the PEP-utilizing enzyme family
G6N59_RS02940	COG3259	Nickel-dependent hydrogenase
G6N59_RS02945	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
G6N59_RS02950	COG3383	formate dehydrogenase (NAD+) activity
G6N59_RS02955	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6N59_RS02970	COG3185	4-Hydroxyphenylpyruvate dioxygenase
G6N59_RS02975	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G6N59_RS03015	COG0071	Belongs to the small heat shock protein (HSP20) family
G6N59_RS03045	COG4941	Belongs to the sigma-70 factor family
G6N59_RS03055	COG0723	plastoquinol--plastocyanin reductase activity
G6N59_RS03065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N59_RS03080	COG5651	PPE family
G6N59_RS03110	COG0531	amino acid
G6N59_RS03130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N59_RS03150	COG2824	Alkylphosphonate utilization operon protein PhnA
G6N59_RS03250	COG2205	protein histidine kinase activity
G6N59_RS03270	COG2814	Major facilitator Superfamily
G6N59_RS03275	COG0583	DNA-binding transcription factor activity
G6N59_RS03295	COG2755	lipolytic protein G-D-S-L family
G6N59_RS03320	COG3022	response to hydroperoxide
G6N59_RS03335	COG1058	Belongs to the CinA family
G6N59_RS03335	COG1546	Belongs to the CinA family
G6N59_RS03345	COG3250	beta-galactosidase activity
G6N59_RS03360	COG2070	2-Nitropropane dioxygenase
G6N59_RS03375	COG0243	molybdopterin cofactor binding
G6N59_RS03425	COG0004	ammonium transporteR
G6N59_RS03440	COG1376	ErfK ybiS ycfS ynhG family protein
G6N59_RS03485	COG0412	Dienelactone hydrolase
G6N59_RS03505	COG2193	ferroxidase activity
G6N59_RS03580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6N59_RS03630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS03635	COG1252	NADH dehydrogenase
G6N59_RS03640	COG0829	nickel cation binding
G6N59_RS03645	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G6N59_RS03650	COG0830	nickel cation binding
G6N59_RS03665	COG0831	urea catabolic process
G6N59_RS03690	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G6N59_RS03700	COG1253	flavin adenine dinucleotide binding
G6N59_RS03705	COG1253	flavin adenine dinucleotide binding
G6N59_RS03735	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6N59_RS03735	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6N59_RS03755	COG1716	ATPase activity
G6N59_RS03760	COG0509	glycine decarboxylation via glycine cleavage system
G6N59_RS03785	COG0653	protein targeting
G6N59_RS03860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N59_RS03910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G6N59_RS03915	COG1914	H( )-stimulated, divalent metal cation uptake system
G6N59_RS03920	COG2239	Acts as a magnesium transporter
G6N59_RS03940	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G6N59_RS03955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N59_RS03955	COG1017	nitric oxide dioxygenase activity
G6N59_RS03975	COG1363	Peptidase, m42
G6N59_RS03985	COG0367	asparagine synthase
G6N59_RS04000	COG2197	response regulator
G6N59_RS04015	COG4585	Histidine kinase
G6N59_RS04020	COG2197	response regulator
G6N59_RS04035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N59_RS04045	COG0277	FAD linked oxidase domain protein
G6N59_RS04065	COG0038	chloride channel
G6N59_RS04070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N59_RS04085	COG0671	phosphoesterase, PA-phosphatase related
G6N59_RS04125	COG3328	transposase activity
G6N59_RS04150	COG2326	polyphosphate kinase activity
G6N59_RS04280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N59_RS04285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N59_RS04290	COG0022	dehydrogenase e1 component
G6N59_RS04290	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N59_RS04295	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N59_RS04300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N59_RS04305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N59_RS04310	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N59_RS04315	COG0644	oxidoreductase
G6N59_RS04340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N59_RS04370	COG0330	HflC and HflK could
G6N59_RS04380	COG1063	alcohol dehydrogenase
G6N59_RS04385	COG0531	amino acid
G6N59_RS04400	COG0589	response to stress
G6N59_RS04435	COG3328	transposase activity
G6N59_RS04450	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G6N59_RS04450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G6N59_RS04460	COG0589	response to stress
G6N59_RS04475	COG4106	trans-aconitate 2-methyltransferase activity
G6N59_RS04500	COG1024	Enoyl-CoA hydratase
G6N59_RS04510	COG0702	epimerase
G6N59_RS04535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N59_RS04555	COG1611	Belongs to the LOG family
G6N59_RS04560	COG2197	response regulator
G6N59_RS04570	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N59_RS04645	COG1160	GTP binding
G6N59_RS04660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6N59_RS04665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G6N59_RS04690	COG0494	nUDIX hydrolase
G6N59_RS04695	COG0504	CTP synthase activity
G6N59_RS04740	COG0647	UMP catabolic process
G6N59_RS04790	COG2835	tetraacyldisaccharide 4'-kinase activity
G6N59_RS04805	COG0488	(ABC) transporter
G6N59_RS04815	COG0165	Argininosuccinate lyase
G6N59_RS04820	COG0137	argininosuccinate synthase activity
G6N59_RS04830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6N59_RS04835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6N59_RS04840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G6N59_RS04845	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G6N59_RS04855	COG0072	phenylalanine-tRNA ligase activity
G6N59_RS04855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6N59_RS04860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G6N59_RS04865	COG0069	glutamate synthase activity
G6N59_RS04885	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS04895	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G6N59_RS04900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G6N59_RS04915	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G6N59_RS04915	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G6N59_RS04970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N59_RS05005	COG1285	pathogenesis
G6N59_RS05010	COG2311	Membrane
G6N59_RS05015	COG4585	Histidine kinase
G6N59_RS05020	COG2197	response regulator
G6N59_RS05050	COG0237	dephospho-CoA kinase activity
G6N59_RS05050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6N59_RS05055	COG0539	negative regulation of cytoplasmic translation
G6N59_RS05075	COG0583	DNA-binding transcription factor activity
G6N59_RS05105	COG1872	DUF167
G6N59_RS05110	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
G6N59_RS05180	COG1126	abc transporter atp-binding protein
G6N59_RS05190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N59_RS05200	COG1271	oxidase subunit
G6N59_RS05205	COG1294	oxidase, subunit
G6N59_RS05210	COG4988	ABC transporter
G6N59_RS05215	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G6N59_RS05260	COG0134	indole-3-glycerol-phosphate synthase activity
G6N59_RS05270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6N59_RS05295	COG0069	glutamate synthase activity
G6N59_RS05300	COG0028	Belongs to the TPP enzyme family
G6N59_RS05305	COG2197	response regulator
G6N59_RS05320	COG1902	pentaerythritol trinitrate reductase activity
G6N59_RS05340	COG0028	Belongs to the TPP enzyme family
G6N59_RS05355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6N59_RS05360	COG2080	2 iron, 2 sulfur cluster binding
G6N59_RS05365	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G6N59_RS05370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N59_RS05380	COG1119	ATPase activity
G6N59_RS05390	COG1984	allophanate hydrolase subunit 2
G6N59_RS05415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G6N59_RS05420	COG0107	imidazoleglycerol-phosphate synthase activity
G6N59_RS05425	COG0483	inositol monophosphate 1-phosphatase activity
G6N59_RS05430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G6N59_RS05435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G6N59_RS05440	COG0131	Imidazoleglycerol-phosphate dehydratase
G6N59_RS05445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N59_RS05485	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G6N59_RS05515	COG1309	transcriptional regulator
G6N59_RS05530	COG0156	8-amino-7-oxononanoate synthase activity
G6N59_RS05540	COG2755	lipolytic protein G-D-S-L family
G6N59_RS05540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N59_RS05590	COG0463	Glycosyl transferase, family 2
G6N59_RS05595	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G6N59_RS05600	COG1228	amidohydrolase
G6N59_RS05660	COG0300	oxidoreductase activity
G6N59_RS05670	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS05685	COG0482	sulfurtransferase activity
G6N59_RS05715	COG2072	flavoprotein involved in K transport
G6N59_RS05720	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G6N59_RS05730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N59_RS05745	COG2132	Multicopper oxidase
G6N59_RS05750	COG0110	maltose O-acetyltransferase activity
G6N59_RS05755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N59_RS05785	COG1119	ATPase activity
G6N59_RS05790	COG2364	Membrane
G6N59_RS05795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N59_RS05805	COG0560	Phosphoserine phosphatase
G6N59_RS05805	COG3830	Belongs to the UPF0237 family
G6N59_RS05830	COG4266	Belongs to the allantoicase family
G6N59_RS05840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G6N59_RS05855	COG1335	isochorismatase
G6N59_RS05860	COG0601	transmembrane transport
G6N59_RS05865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6N59_RS05875	COG1309	transcriptional regulator
G6N59_RS05885	COG1064	alcohol dehydrogenase
G6N59_RS05905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6N59_RS05915	COG1309	transcriptional regulator
G6N59_RS05920	COG0644	oxidoreductase
G6N59_RS05955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G6N59_RS05965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6N59_RS06005	COG2508	Transcriptional regulator
G6N59_RS06050	COG2184	nucleotidyltransferase activity
G6N59_RS06080	COG1966	Carbon starvation protein
G6N59_RS06090	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS06115	COG0477	Major facilitator Superfamily
G6N59_RS06120	COG1802	Transcriptional regulator
G6N59_RS06125	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06130	COG0183	Belongs to the thiolase family
G6N59_RS06140	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06175	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06180	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06210	COG0745	RESPONSE REGULATOR receiver
G6N59_RS06215	COG2205	protein histidine kinase activity
G6N59_RS06220	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N59_RS06230	COG0415	Belongs to the DNA photolyase family
G6N59_RS06250	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06260	COG0840	transmembrane signaling receptor activity
G6N59_RS06270	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS06290	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS06295	COG1403	HNH endonuclease
G6N59_RS06305	COG2124	cytochrome p450
G6N59_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS06340	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS06345	COG1309	transcriptional regulator
G6N59_RS06350	COG1024	Enoyl-CoA hydratase
G6N59_RS06360	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS06370	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS06375	COG2188	Transcriptional regulator
G6N59_RS06380	COG3386	PFAM SMP-30 Gluconolaconase
G6N59_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS06395	COG2072	flavoprotein involved in K transport
G6N59_RS06400	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS06405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N59_RS06410	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06420	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06425	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N59_RS06470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N59_RS06475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N59_RS06510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N59_RS06515	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS06535	COG0789	Transcriptional regulator
G6N59_RS06540	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06545	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06575	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6N59_RS06600	COG2084	Dehydrogenase
G6N59_RS06605	COG2124	cytochrome p450
G6N59_RS06620	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS06670	COG1228	amidohydrolase
G6N59_RS06680	COG4638	Rieske (2fe-2S)
G6N59_RS06685	COG1309	transcriptional regulator
G6N59_RS06700	COG0714	Associated with various cellular activities
G6N59_RS06725	COG1309	transcriptional regulator
G6N59_RS06730	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06735	COG1024	Enoyl-CoA hydratase
G6N59_RS06740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N59_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS06765	COG4638	Rieske (2fe-2S)
G6N59_RS06775	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6N59_RS06785	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06790	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06805	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06815	COG1946	Acyl-CoA thioesterase
G6N59_RS06820	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS06855	COG1309	transcriptional regulator
G6N59_RS06875	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06880	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS06885	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS06890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N59_RS06895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N59_RS06905	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N59_RS06930	COG1024	Enoyl-CoA hydratase
G6N59_RS06960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N59_RS06970	COG4638	Rieske (2fe-2S)
G6N59_RS06975	COG1012	belongs to the aldehyde dehydrogenase family
G6N59_RS06980	COG2124	cytochrome p450
G6N59_RS07005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6N59_RS07010	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS07015	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS07025	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS07035	COG1024	Enoyl-CoA hydratase
G6N59_RS07040	COG0300	oxidoreductase activity
G6N59_RS07045	COG1024	Enoyl-CoA hydratase
G6N59_RS07060	COG1024	Enoyl-CoA hydratase
G6N59_RS07075	COG1024	Enoyl-CoA hydratase
G6N59_RS07080	COG1024	Enoyl-CoA hydratase
G6N59_RS07085	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS07095	COG1946	Acyl-CoA thioesterase
G6N59_RS07200	COG0477	Major facilitator Superfamily
G6N59_RS07305	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G6N59_RS07315	COG2884	Cell division ATP-binding protein ftsE
G6N59_RS07325	COG0668	transmembrane transport
G6N59_RS07330	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G6N59_RS07350	COG0483	inositol monophosphate 1-phosphatase activity
G6N59_RS07360	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS07365	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N59_RS07375	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS07390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N59_RS07395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N59_RS07405	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS07430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N59_RS07435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N59_RS07440	COG0649	NAD binding
G6N59_RS07455	COG1034	ATP synthesis coupled electron transport
G6N59_RS07460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G6N59_RS07465	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N59_RS07475	COG0713	ATP synthesis coupled electron transport
G6N59_RS07575	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS07580	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS07585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N59_RS07590	COG0583	DNA-binding transcription factor activity
G6N59_RS07600	COG2072	flavoprotein involved in K transport
G6N59_RS07605	COG2267	carboxylic ester hydrolase activity
G6N59_RS07630	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS07635	COG1012	belongs to the aldehyde dehydrogenase family
G6N59_RS07650	COG1403	HNH endonuclease
G6N59_RS07680	COG1116	anion transmembrane transporter activity
G6N59_RS07695	COG0583	DNA-binding transcription factor activity
G6N59_RS07760	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS07780	COG2172	sigma factor antagonist activity
G6N59_RS07785	COG1366	Belongs to the anti-sigma-factor antagonist family
G6N59_RS07790	COG1366	Belongs to the anti-sigma-factor antagonist family
G6N59_RS07840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N59_RS07845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N59_RS07850	COG1309	transcriptional regulator
G6N59_RS07855	COG1024	Enoyl-CoA hydratase
G6N59_RS07865	COG1959	2 iron, 2 sulfur cluster binding
G6N59_RS07880	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS07900	COG1053	succinate dehydrogenase
G6N59_RS07905	COG3384	dioxygenase
G6N59_RS07910	COG2072	flavoprotein involved in K transport
G6N59_RS07960	COG0714	Associated with various cellular activities
G6N59_RS07980	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N59_RS08150	COG3480	Lon protease (S16) C-terminal proteolytic domain
G6N59_RS08165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N59_RS08195	COG0475	glutathione-regulated potassium exporter activity
G6N59_RS08195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N59_RS08210	COG0210	DNA helicase
G6N59_RS08215	COG0596	Alpha beta hydrolase
G6N59_RS08220	COG3695	enzyme binding
G6N59_RS08290	COG0406	alpha-ribazole phosphatase activity
G6N59_RS08305	COG5002	protein histidine kinase activity
G6N59_RS08320	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G6N59_RS08325	COG3012	SEC-C Motif Domain Protein
G6N59_RS08330	COG1597	lipid kinase activity
G6N59_RS08345	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N59_RS08350	COG5662	AntiSigma factor
G6N59_RS08355	COG1595	DNA-templated transcription, initiation
G6N59_RS08360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G6N59_RS08365	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS08390	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N59_RS08395	COG2135	peptidase activity
G6N59_RS08400	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6N59_RS08405	COG1162	GTPase activity
G6N59_RS08425	COG2326	polyphosphate kinase activity
G6N59_RS08440	COG0653	protein targeting
G6N59_RS08445	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G6N59_RS08455	COG5401	PFAM Sporulation and spore germination
G6N59_RS08460	COG5002	protein histidine kinase activity
G6N59_RS08465	COG0745	RESPONSE REGULATOR receiver
G6N59_RS08495	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G6N59_RS08515	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N59_RS08525	COG1482	cell wall glycoprotein biosynthetic process
G6N59_RS08535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N59_RS08575	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G6N59_RS08575	COG0778	Nitroreductase
G6N59_RS08595	COG1316	TRANSCRIPTIONal
G6N59_RS08615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G6N59_RS08620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G6N59_RS08685	COG3206	protein involved in exopolysaccharide biosynthesis
G6N59_RS08685	COG0489	protein tyrosine kinase activity
G6N59_RS08735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N59_RS08760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N59_RS08765	COG1595	DNA-templated transcription, initiation
G6N59_RS08770	COG5343	regulation of RNA biosynthetic process
G6N59_RS08795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N59_RS08800	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G6N59_RS08820	COG4770	biotin carboxylase activity
G6N59_RS08835	COG0640	Transcriptional regulator
G6N59_RS08840	COG3832	glyoxalase III activity
G6N59_RS08860	COG1522	sequence-specific DNA binding
G6N59_RS08870	COG1012	belongs to the aldehyde dehydrogenase family
G6N59_RS08895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6N59_RS08900	COG1201	RNA secondary structure unwinding
G6N59_RS08905	COG1942	4-Oxalocrotonate Tautomerase
G6N59_RS08910	COG2070	2-Nitropropane dioxygenase
G6N59_RS08930	COG0789	Transcriptional regulator
G6N59_RS08955	COG1309	transcriptional regulator
G6N59_RS08980	COG0523	cobalamin synthesis protein
G6N59_RS08985	COG2353	YceI-like domain
G6N59_RS09005	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS09010	COG0564	pseudouridine synthase activity
G6N59_RS09035	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N59_RS09035	COG1473	amidohydrolase
G6N59_RS09050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N59_RS09065	COG0791	NLP P60 protein
G6N59_RS09080	COG0596	Alpha beta hydrolase
G6N59_RS09120	COG2009	succinate dehydrogenase
G6N59_RS09130	COG1053	succinate dehydrogenase
G6N59_RS09135	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G6N59_RS09160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N59_RS09170	COG1595	DNA-templated transcription, initiation
G6N59_RS09185	COG1686	Belongs to the peptidase S11 family
G6N59_RS09190	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G6N59_RS09205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6N59_RS09240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N59_RS09270	COG0714	Associated with various cellular activities
G6N59_RS09305	COG1506	peptidase
G6N59_RS09305	COG0823	Involved in the tonB-independent uptake of proteins
G6N59_RS09310	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N59_RS09315	COG0842	Transport permease protein
G6N59_RS09315	COG1716	ATPase activity
G6N59_RS09315	COG1131	(ABC) transporter
G6N59_RS09325	COG1357	PFAM Pentapeptide repeats (8 copies)
G6N59_RS09330	COG3757	hydrolase, family 25
G6N59_RS09345	COG2018	Roadblock/LC7 domain
G6N59_RS09350	COG2205	protein histidine kinase activity
G6N59_RS09355	COG1309	transcriptional regulator
G6N59_RS09360	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6N59_RS09380	COG0587	DNA-directed DNA polymerase activity
G6N59_RS09395	COG4552	Acetyltransferase involved in intracellular survival and related
G6N59_RS09400	COG1454	alcohol dehydrogenase
G6N59_RS09460	COG0657	acetylesterase activity
G6N59_RS09480	COG0784	Response regulator, receiver
G6N59_RS09485	COG4251	negative regulation of phosphorylation
G6N59_RS09520	COG0784	Response regulator, receiver
G6N59_RS09580	COG1846	Transcriptional regulator
G6N59_RS09610	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS09630	COG0183	Belongs to the thiolase family
G6N59_RS09635	COG0251	oxidation-reduction process
G6N59_RS09655	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS09665	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N59_RS09665	COG1024	Enoyl-CoA hydratase
G6N59_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS09680	COG2226	methyltransferase
G6N59_RS09680	COG0596	Alpha beta hydrolase
G6N59_RS09680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N59_RS09685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N59_RS09690	COG1902	pentaerythritol trinitrate reductase activity
G6N59_RS09690	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N59_RS09705	COG0300	oxidoreductase activity
G6N59_RS09720	COG0531	amino acid
G6N59_RS09740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6N59_RS09790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G6N59_RS09800	COG1309	transcriptional regulator
G6N59_RS09805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N59_RS09855	COG4221	oxidoreductase activity
G6N59_RS09870	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G6N59_RS09880	COG0069	glutamate synthase activity
G6N59_RS09900	COG1764	response to oxidative stress
G6N59_RS09905	COG1846	Transcriptional regulator
G6N59_RS09945	COG0519	Catalyzes the synthesis of GMP from XMP
G6N59_RS09945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6N59_RS09970	COG0516	GMP reductase activity
G6N59_RS10005	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
G6N59_RS10015	COG0375	protein maturation
G6N59_RS10065	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G6N59_RS10070	COG0298	carbon dioxide binding
G6N59_RS10075	COG0409	Hydrogenase expression formation protein
G6N59_RS10105	COG1309	transcriptional regulator
G6N59_RS10115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G6N59_RS10120	COG0656	L-ascorbic acid biosynthetic process
G6N59_RS10130	COG1309	transcriptional regulator
G6N59_RS10150	COG1024	Enoyl-CoA hydratase
G6N59_RS10165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G6N59_RS10180	COG2508	Transcriptional regulator
G6N59_RS10210	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G6N59_RS10215	COG0456	acetyltransferase
G6N59_RS10235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G6N59_RS10240	COG0076	glutamate decarboxylase activity
G6N59_RS10255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6N59_RS10305	COG1012	belongs to the aldehyde dehydrogenase family
G6N59_RS10320	COG2814	Major facilitator Superfamily
G6N59_RS10325	COG4638	Rieske (2fe-2S)
G6N59_RS10350	COG1802	Transcriptional regulator
G6N59_RS10355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6N59_RS10390	COG1902	pentaerythritol trinitrate reductase activity
G6N59_RS10390	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N59_RS10410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G6N59_RS10415	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G6N59_RS10425	COG4303	Ethanolamine ammonia lyase large subunit
G6N59_RS10430	COG0531	amino acid
G6N59_RS10450	COG4842	Belongs to the WXG100 family
G6N59_RS10460	COG1674	ftsk spoiiie
G6N59_RS10470	COG1404	Belongs to the peptidase S8 family
G6N59_RS10525	COG0789	Transcriptional regulator
G6N59_RS10580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6N59_RS10620	COG0203	ribosomal protein L17
G6N59_RS10625	COG0202	RNA polymerase activity
G6N59_RS10630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G6N59_RS10635	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G6N59_RS10640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G6N59_RS10645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G6N59_RS10650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G6N59_RS10655	COG0492	ferredoxin-NADP+ reductase activity
G6N59_RS10660	COG3852	Histidine kinase
G6N59_RS10695	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS10745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N59_RS10750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N59_RS10780	COG0563	adenylate kinase activity
G6N59_RS10790	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N59_RS10795	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N59_RS10805	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N59_RS10810	COG0616	signal peptide processing
G6N59_RS10825	COG0200	Binds to the 23S rRNA
G6N59_RS10830	COG1841	ribosomal large subunit assembly
G6N59_RS10835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G6N59_RS10840	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G6N59_RS10845	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G6N59_RS10850	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G6N59_RS10855	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6N59_RS10870	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G6N59_RS10890	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G6N59_RS10900	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G6N59_RS10905	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G6N59_RS10910	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G6N59_RS10915	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G6N59_RS10920	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G6N59_RS10925	COG0089	rRNA binding
G6N59_RS10930	COG0088	Forms part of the polypeptide exit tunnel
G6N59_RS10935	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G6N59_RS10940	COG0051	transcription antitermination factor activity, RNA binding
G6N59_RS10970	COG0477	Major facilitator Superfamily
G6N59_RS11000	COG0535	radical SAM domain protein
G6N59_RS11035	COG1834	amidinotransferase
G6N59_RS11040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6N59_RS11065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G6N59_RS11070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G6N59_RS11075	COG0049	tRNA binding
G6N59_RS11105	COG1024	Enoyl-CoA hydratase
G6N59_RS11120	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS11125	COG1113	amino acid transport
G6N59_RS11130	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G6N59_RS11140	COG1755	Isoprenylcysteine carboxyl methyltransferase
G6N59_RS11145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N59_RS11160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6N59_RS11180	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G6N59_RS11200	COG1733	regulation of RNA biosynthetic process
G6N59_RS11250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N59_RS11255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N59_RS11275	COG0081	regulation of translation
G6N59_RS11290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G6N59_RS11305	COG2030	dehydratase
G6N59_RS11315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G6N59_RS11330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N59_RS11345	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G6N59_RS11350	COG1074	ATP-dependent DNA helicase activity
G6N59_RS11360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N59_RS11375	COG1376	ErfK ybiS ycfS ynhG family protein
G6N59_RS11395	COG0583	DNA-binding transcription factor activity
G6N59_RS11400	COG0701	Predicted permease
G6N59_RS11440	COG1666	GTP binding
G6N59_RS11465	COG2205	protein histidine kinase activity
G6N59_RS11470	COG0745	RESPONSE REGULATOR receiver
G6N59_RS11475	COG0659	secondary active sulfate transmembrane transporter activity
G6N59_RS11480	COG1396	sequence-specific DNA binding
G6N59_RS11500	COG0501	Belongs to the peptidase M48B family
G6N59_RS11510	COG0644	oxidoreductase
G6N59_RS11520	COG3123	guanosine phosphorylase activity
G6N59_RS11530	COG2226	methyltransferase
G6N59_RS11535	COG4221	oxidoreductase activity
G6N59_RS11555	COG0438	transferase activity, transferring glycosyl groups
G6N59_RS11570	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G6N59_RS11585	COG4977	sequence-specific DNA binding
G6N59_RS11590	COG2217	Heavy metal translocating P-type atpase
G6N59_RS11595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N59_RS11650	COG4948	Mandelate Racemase Muconate Lactonizing
G6N59_RS11660	COG1228	amidohydrolase
G6N59_RS11665	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS11670	COG2186	Transcriptional regulator
G6N59_RS11675	COG2807	transmembrane transport
G6N59_RS11695	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6N59_RS11705	COG0778	Nitroreductase
G6N59_RS11750	COG2070	2-Nitropropane dioxygenase
G6N59_RS11755	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G6N59_RS11780	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N59_RS11790	COG0785	Cytochrome C biogenesis protein
G6N59_RS11800	COG0406	alpha-ribazole phosphatase activity
G6N59_RS11805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G6N59_RS11900	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS11930	COG1648	precorrin-2 dehydrogenase activity
G6N59_RS11930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N59_RS11935	COG0181	hydroxymethylbilane synthase activity
G6N59_RS11955	COG2030	dehydratase
G6N59_RS11980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G6N59_RS12010	COG5002	protein histidine kinase activity
G6N59_RS12025	COG0438	transferase activity, transferring glycosyl groups
G6N59_RS12045	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G6N59_RS12060	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N59_RS12100	COG2733	membrane
G6N59_RS12110	COG2326	polyphosphate kinase activity
G6N59_RS12115	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N59_RS12125	COG2224	Isocitrate lyase
G6N59_RS12160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N59_RS12165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N59_RS12175	COG1505	serine-type exopeptidase activity
G6N59_RS12185	COG2326	polyphosphate kinase activity
G6N59_RS12190	COG1012	belongs to the aldehyde dehydrogenase family
G6N59_RS12250	COG0714	Associated with various cellular activities
G6N59_RS12260	COG0459	protein refolding
G6N59_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS12315	COG1309	transcriptional regulator
G6N59_RS12325	COG0546	phosphoglycolate phosphatase activity
G6N59_RS12330	COG4221	oxidoreductase activity
G6N59_RS12345	COG1183	phosphatidylcholine synthase activity
G6N59_RS12350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N59_RS12355	COG3226	Transcriptional regulator
G6N59_RS12385	COG2111	Na H antiporter
G6N59_RS12385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6N59_RS12405	COG2212	antiporter activity
G6N59_RS12430	COG2032	superoxide dismutase activity
G6N59_RS12445	COG0242	peptide deformylase activity
G6N59_RS12480	COG0657	acetylesterase activity
G6N59_RS12490	COG2409	Drug exporters of the RND superfamily
G6N59_RS12505	COG0515	serine threonine protein kinase
G6N59_RS12525	COG2072	flavoprotein involved in K transport
G6N59_RS12545	COG2814	Major facilitator Superfamily
G6N59_RS12555	COG0351	phosphomethylpyrimidine kinase
G6N59_RS12590	COG2234	aminopeptidase activity
G6N59_RS12595	COG2234	aminopeptidase activity
G6N59_RS12605	COG1131	(ABC) transporter
G6N59_RS12615	COG2022	thiamine diphosphate biosynthetic process
G6N59_RS12625	COG2022	thiamine diphosphate biosynthetic process
G6N59_RS12625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N59_RS12630	COG0352	thiamine-phosphate diphosphorylase activity
G6N59_RS12645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N59_RS12650	COG0515	serine threonine protein kinase
G6N59_RS12660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G6N59_RS12670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS12675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N59_RS12695	COG4221	oxidoreductase activity
G6N59_RS12705	COG0583	DNA-binding transcription factor activity
G6N59_RS12740	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G6N59_RS12770	COG0739	heme binding
G6N59_RS12780	COG2409	Drug exporters of the RND superfamily
G6N59_RS12790	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G6N59_RS12800	COG1994	Peptidase M50
G6N59_RS12830	COG0586	Pfam SNARE associated Golgi protein
G6N59_RS12865	COG3851	Histidine kinase
G6N59_RS12870	COG2197	response regulator
G6N59_RS12885	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G6N59_RS12905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N59_RS12930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N59_RS12935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N59_RS12940	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS12950	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS12955	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS12960	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS12975	COG2070	2-Nitropropane dioxygenase
G6N59_RS13005	COG2124	cytochrome p450
G6N59_RS13015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS13050	COG4638	Rieske (2fe-2S)
G6N59_RS13090	COG0514	ATP-dependent DNA helicase (RecQ)
G6N59_RS13100	COG0701	Predicted permease
G6N59_RS13115	COG0300	oxidoreductase activity
G6N59_RS13120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N59_RS13130	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G6N59_RS13135	COG3971	2-oxopent-4-enoate hydratase activity
G6N59_RS13140	COG1053	succinate dehydrogenase
G6N59_RS13145	COG2030	dehydratase
G6N59_RS13180	COG2030	dehydratase
G6N59_RS13185	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS13190	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS13195	COG2124	cytochrome p450
G6N59_RS13200	COG0183	Belongs to the thiolase family
G6N59_RS13210	COG0406	alpha-ribazole phosphatase activity
G6N59_RS13220	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS13225	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS13230	COG1024	Enoyl-CoA hydratase
G6N59_RS13275	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS13290	COG0183	Belongs to the thiolase family
G6N59_RS13295	COG1309	transcriptional regulator
G6N59_RS13300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N59_RS13310	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS13315	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS13325	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS13330	COG0436	Aminotransferase
G6N59_RS13340	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G6N59_RS13370	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS13380	COG0427	acetyl-CoA hydrolase
G6N59_RS13390	COG2301	Belongs to the HpcH HpaI aldolase family
G6N59_RS13405	COG1024	Enoyl-CoA hydratase
G6N59_RS13405	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N59_RS13425	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS13435	COG0183	Belongs to the thiolase family
G6N59_RS13445	COG0183	Belongs to the thiolase family
G6N59_RS13460	COG4638	Rieske (2fe-2S)
G6N59_RS13465	COG1024	Enoyl-CoA hydratase
G6N59_RS13470	COG1024	Enoyl-CoA hydratase
G6N59_RS13475	COG1024	Enoyl-CoA hydratase
G6N59_RS13480	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS13495	COG0346	lactoylglutathione lyase activity
G6N59_RS13505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N59_RS13530	COG1309	transcriptional regulator
G6N59_RS13545	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS13550	COG1309	transcriptional regulator
G6N59_RS13560	COG1609	Transcriptional regulator
G6N59_RS13570	COG1116	anion transmembrane transporter activity
G6N59_RS13585	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G6N59_RS13605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N59_RS13610	COG0215	cysteine-tRNA ligase activity
G6N59_RS13615	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G6N59_RS13620	COG1329	Transcriptional regulator
G6N59_RS13635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G6N59_RS13640	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G6N59_RS13655	COG1194	a g-specific adenine glycosylase
G6N59_RS13695	COG1309	transcriptional regulator
G6N59_RS13705	COG1396	sequence-specific DNA binding
G6N59_RS13705	COG3800	Transcriptional regulator
G6N59_RS13710	COG2079	MmgE PrpD family protein
G6N59_RS13715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G6N59_RS13745	COG1120	ATPase activity
G6N59_RS13785	COG0393	Putative heavy-metal-binding
G6N59_RS13810	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G6N59_RS13820	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G6N59_RS13830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G6N59_RS13860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G6N59_RS13865	COG0302	gtp cyclohydrolase
G6N59_RS13870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N59_RS13875	COG2267	carboxylic ester hydrolase activity
G6N59_RS13890	COG3383	formate dehydrogenase (NAD+) activity
G6N59_RS13910	COG2027	D-alanyl-D-alanine carboxypeptidase
G6N59_RS13930	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N59_RS13935	COG2124	cytochrome p450
G6N59_RS13990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N59_RS14010	COG0470	DNA polymerase III
G6N59_RS14020	COG1754	DNA topoisomerase type I activity
G6N59_RS14020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G6N59_RS14030	COG1278	Cold shock
G6N59_RS14035	COG1205	dead DEAH box helicase
G6N59_RS14035	COG1111	helicase
G6N59_RS14095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N59_RS14145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N59_RS14150	COG0251	oxidation-reduction process
G6N59_RS14175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N59_RS14180	COG1408	metallophosphoesterase
G6N59_RS14185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N59_RS14200	COG1309	transcriptional regulator
G6N59_RS14205	COG0477	Major facilitator Superfamily
G6N59_RS14215	COG0589	response to stress
G6N59_RS14215	COG0475	glutathione-regulated potassium exporter activity
G6N59_RS14230	COG0667	Aldo Keto reductase
G6N59_RS14245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N59_RS14250	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G6N59_RS14260	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N59_RS14265	COG3572	ergothioneine biosynthetic process
G6N59_RS14280	COG4290	ribonuclease
G6N59_RS14315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N59_RS14350	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
G6N59_RS14355	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G6N59_RS14365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G6N59_RS14370	COG1492	cobalamin metabolic process
G6N59_RS14380	COG3321	synthase
G6N59_RS14380	COG0604	alcohol dehydrogenase
G6N59_RS14400	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G6N59_RS14410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G6N59_RS14415	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS14420	COG2188	Transcriptional regulator
G6N59_RS14460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N59_RS14475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N59_RS14495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N59_RS14530	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
G6N59_RS14560	COG1793	dna ligase
G6N59_RS14565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N59_RS14570	COG0300	oxidoreductase activity
G6N59_RS14580	COG0343	queuine tRNA-ribosyltransferase activity
G6N59_RS14595	COG0531	amino acid
G6N59_RS14625	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS14645	COG1132	(ABC) transporter
G6N59_RS14680	COG0287	Prephenate dehydrogenase
G6N59_RS14695	COG1174	glycine betaine transport
G6N59_RS14700	COG0517	IMP dehydrogenase activity
G6N59_RS14700	COG1125	glycine betaine transport
G6N59_RS14710	COG5416	Lipopolysaccharide assembly protein A domain
G6N59_RS14725	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS14740	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G6N59_RS14765	COG1033	growth of symbiont in host cell
G6N59_RS14765	COG2409	Drug exporters of the RND superfamily
G6N59_RS14820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N59_RS14835	COG1968	undecaprenyl-diphosphatase activity
G6N59_RS14895	COG0604	alcohol dehydrogenase
G6N59_RS14920	COG1216	Glycosyl transferase, family 2
G6N59_RS14935	COG1733	regulation of RNA biosynthetic process
G6N59_RS14945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N59_RS14950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N59_RS14965	COG0277	FAD linked oxidase domain protein
G6N59_RS14970	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS14985	COG4716	Myosin-crossreactive antigen
G6N59_RS15035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N59_RS15060	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N59_RS15065	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N59_RS15075	COG0671	phosphoesterase, PA-phosphatase related
G6N59_RS15080	COG1216	Glycosyl transferase, family 2
G6N59_RS15100	COG0561	phosphatase activity
G6N59_RS15110	COG0204	Acyl-transferase
G6N59_RS15120	COG2146	nitrite reductase [NAD(P)H] activity
G6N59_RS15120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G6N59_RS15165	COG0406	alpha-ribazole phosphatase activity
G6N59_RS15185	COG1528	Iron-storage protein
G6N59_RS15210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G6N59_RS15250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6N59_RS15255	COG2072	flavoprotein involved in K transport
G6N59_RS15260	COG1309	transcriptional regulator
G6N59_RS15275	COG1309	transcriptional regulator
G6N59_RS15280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G6N59_RS15300	COG1796	DNA polymerase
G6N59_RS15300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G6N59_RS15310	COG0726	polysaccharide deacetylase
G6N59_RS15320	COG0067	glutamate synthase
G6N59_RS15320	COG0070	glutamate synthase
G6N59_RS15320	COG0069	glutamate synthase activity
G6N59_RS15325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G6N59_RS15360	COG0531	amino acid
G6N59_RS15375	COG0191	fructose-bisphosphate aldolase activity
G6N59_RS15385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G6N59_RS15390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6N59_RS15400	COG2197	response regulator
G6N59_RS15440	COG0531	amino acid
G6N59_RS15480	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G6N59_RS15515	COG0647	UMP catabolic process
G6N59_RS15520	COG0069	glutamate synthase activity
G6N59_RS15525	COG2218	PFAM glutamate synthase alpha subunit domain protein
G6N59_RS15530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G6N59_RS15535	COG0174	glutamine synthetase
G6N59_RS15545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G6N59_RS15575	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N59_RS15580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N59_RS15595	COG0596	Alpha beta hydrolase
G6N59_RS15620	COG1024	Enoyl-CoA hydratase
G6N59_RS15630	COG0842	Transport permease protein
G6N59_RS15630	COG1129	ABC transporter
G6N59_RS15650	COG3281	Trehalose synthase
G6N59_RS15665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G6N59_RS15695	COG1022	Amp-dependent synthetase and ligase
G6N59_RS15695	COG3320	Male sterility
G6N59_RS15700	COG1022	Amp-dependent synthetase and ligase
G6N59_RS15700	COG3320	Male sterility
G6N59_RS15705	COG0697	spore germination
G6N59_RS15710	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS15715	COG1063	alcohol dehydrogenase
G6N59_RS15740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6N59_RS15745	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G6N59_RS15750	COG0705	Rhomboid family
G6N59_RS15755	COG1946	Acyl-CoA thioesterase
G6N59_RS15790	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS15810	COG0129	dihydroxy-acid dehydratase activity
G6N59_RS15820	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N59_RS15845	COG1643	Atp-dependent helicase
G6N59_RS15855	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS15870	COG3961	Belongs to the TPP enzyme family
G6N59_RS15880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N59_RS15895	COG2226	methyltransferase
G6N59_RS15915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS15950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N59_RS15975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N59_RS15995	COG4399	Belongs to the UPF0754 family
G6N59_RS16010	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS16015	COG0596	Alpha beta hydrolase
G6N59_RS16040	COG1376	ErfK ybiS ycfS ynhG family protein
G6N59_RS16045	COG0833	amino acid
G6N59_RS16050	COG0277	FAD linked oxidase domain protein
G6N59_RS16110	COG2318	DinB family
G6N59_RS16115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N59_RS16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS16140	COG2030	dehydratase
G6N59_RS16160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N59_RS16165	COG1231	oxidoreductase activity
G6N59_RS16185	COG1113	amino acid transport
G6N59_RS16190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N59_RS16205	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G6N59_RS16250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G6N59_RS16260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS16265	COG0174	glutamine synthetase
G6N59_RS16275	COG1464	Belongs to the NlpA lipoprotein family
G6N59_RS16280	COG0745	RESPONSE REGULATOR receiver
G6N59_RS16285	COG3757	hydrolase, family 25
G6N59_RS16295	COG0488	(ABC) transporter
G6N59_RS16320	COG2409	Drug exporters of the RND superfamily
G6N59_RS16320	COG1033	growth of symbiont in host cell
G6N59_RS16470	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS16490	COG0531	amino acid
G6N59_RS16525	COG2197	response regulator
G6N59_RS16550	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G6N59_RS16555	COG0629	single-stranded DNA binding
G6N59_RS16560	COG0360	Binds together with S18 to 16S ribosomal RNA
G6N59_RS16575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N59_RS16595	COG1260	myo-inositol-1-phosphate synthase
G6N59_RS16605	COG3634	alkyl hydroperoxide reductase activity
G6N59_RS16620	COG0765	amino acid transport
G6N59_RS16625	COG1126	abc transporter atp-binding protein
G6N59_RS16640	COG4221	oxidoreductase activity
G6N59_RS16645	COG0495	leucyl-tRNA aminoacylation
G6N59_RS16660	COG1678	Uncharacterized ACR, COG1678
G6N59_RS16675	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS16695	COG0617	tRNA 3'-terminal CCA addition
G6N59_RS16715	COG1595	DNA-templated transcription, initiation
G6N59_RS16735	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N59_RS16735	COG3409	Peptidoglycan-binding domain 1 protein
G6N59_RS16750	COG0667	Aldo Keto reductase
G6N59_RS16760	COG2267	carboxylic ester hydrolase activity
G6N59_RS16775	COG1192	Involved in chromosome partitioning
G6N59_RS16780	COG0357	Ribosomal RNA small subunit methyltransferase G
G6N59_RS16790	COG0706	membrane insertase activity
G6N59_RS16795	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G6N59_RS16800	COG0594	ribonuclease P activity
G6N59_RS16805	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G6N59_RS16815	COG0592	DNA-directed DNA polymerase activity
G6N59_RS16820	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G6N59_RS16825	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6N59_RS16830	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G6N59_RS16835	COG0187	DNA topoisomerase II activity
G6N59_RS16840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6N59_RS16865	COG1309	transcriptional regulator
G6N59_RS16880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G6N59_RS16905	COG2815	serine threonine protein kinase
G6N59_RS16905	COG0515	serine threonine protein kinase
G6N59_RS16910	COG0515	serine threonine protein kinase
G6N59_RS16915	COG0768	penicillin binding
G6N59_RS16930	COG1716	ATPase activity
G6N59_RS16935	COG1716	ATPase activity
G6N59_RS16945	COG2801	Transposase and inactivated derivatives
G6N59_RS16945	COG3415	Transposase
G6N59_RS16970	COG2226	methyltransferase
G6N59_RS17015	COG0747	negative chemotaxis
G6N59_RS17025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6N59_RS17045	COG0596	Alpha beta hydrolase
G6N59_RS17100	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS17120	COG1309	transcriptional regulator
G6N59_RS17175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N59_RS17235	COG0464	growth
G6N59_RS17250	COG1674	ftsk spoiiie
G6N59_RS17265	COG4842	Belongs to the WXG100 family
G6N59_RS17270	COG4842	Belongs to the WXG100 family
G6N59_RS17295	COG1716	ATPase activity
G6N59_RS17295	COG1131	(ABC) transporter
G6N59_RS17295	COG0842	Transport permease protein
G6N59_RS17330	COG1404	Belongs to the peptidase S8 family
G6N59_RS17340	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G6N59_RS17340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6N59_RS17340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6N59_RS17345	COG1105	Belongs to the carbohydrate kinase PfkB family
G6N59_RS17355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N59_RS17380	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N59_RS17385	COG1012	belongs to the aldehyde dehydrogenase family
G6N59_RS17390	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS17395	COG0604	alcohol dehydrogenase
G6N59_RS17395	COG3321	synthase
G6N59_RS17395	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS17410	COG2365	Tyrosine phosphatase family
G6N59_RS17430	COG4585	Histidine kinase
G6N59_RS17440	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G6N59_RS17445	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G6N59_RS17450	COG1309	transcriptional regulator
G6N59_RS17455	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS17485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N59_RS17490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N59_RS17515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N59_RS17600	COG0671	phosphoesterase, PA-phosphatase related
G6N59_RS17605	COG0745	RESPONSE REGULATOR receiver
G6N59_RS17610	COG2205	protein histidine kinase activity
G6N59_RS17630	COG2267	carboxylic ester hydrolase activity
G6N59_RS17655	COG4122	O-methyltransferase activity
G6N59_RS17685	COG3268	Saccharopine dehydrogenase
G6N59_RS17705	COG1937	Protein conserved in bacteria
G6N59_RS17710	COG1376	ErfK ybiS ycfS ynhG family protein
G6N59_RS17715	COG3590	peptidase
G6N59_RS17735	COG2409	Drug exporters of the RND superfamily
G6N59_RS17755	COG1196	nuclear chromosome segregation
G6N59_RS17755	COG0741	lytic transglycosylase activity
G6N59_RS17755	COG0739	heme binding
G6N59_RS17770	COG2409	Drug exporters of the RND superfamily
G6N59_RS17790	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G6N59_RS17805	COG2030	dehydratase
G6N59_RS17820	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS17830	COG4638	Rieske (2fe-2S)
G6N59_RS17870	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS17895	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS17920	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS17945	COG0500	methyltransferase
G6N59_RS17955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G6N59_RS17980	COG4981	capsule polysaccharide biosynthetic process
G6N59_RS17990	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N59_RS17995	COG1309	transcriptional regulator
G6N59_RS18010	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G6N59_RS18015	COG2030	dehydratase
G6N59_RS18020	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS18025	COG0183	Belongs to the thiolase family
G6N59_RS18030	COG2267	carboxylic ester hydrolase activity
G6N59_RS18050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS18075	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS18090	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS18130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N59_RS18135	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G6N59_RS18150	COG0438	transferase activity, transferring glycosyl groups
G6N59_RS18165	COG2226	methyltransferase
G6N59_RS18185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N59_RS18185	COG2755	lipolytic protein G-D-S-L family
G6N59_RS18230	COG0489	protein tyrosine kinase activity
G6N59_RS18230	COG3206	protein involved in exopolysaccharide biosynthesis
G6N59_RS18245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N59_RS18245	COG2755	lipolytic protein G-D-S-L family
G6N59_RS18265	COG5651	PPE family
G6N59_RS18355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G6N59_RS18365	COG2146	nitrite reductase [NAD(P)H] activity
G6N59_RS18365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N59_RS18380	COG2197	response regulator
G6N59_RS18425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G6N59_RS18445	COG1376	ErfK ybiS ycfS ynhG family protein
G6N59_RS18480	COG1316	TRANSCRIPTIONal
G6N59_RS18500	COG0531	amino acid
G6N59_RS18505	COG0789	Transcriptional regulator
G6N59_RS18525	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS18535	COG0300	oxidoreductase activity
G6N59_RS18545	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS18550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N59_RS18600	COG0464	growth
G6N59_RS18605	COG3266	domain, Protein
G6N59_RS18610	COG1674	ftsk spoiiie
G6N59_RS18630	COG4842	Belongs to the WXG100 family
G6N59_RS18645	COG1404	Belongs to the peptidase S8 family
G6N59_RS18665	COG4106	trans-aconitate 2-methyltransferase activity
G6N59_RS18680	COG4424	Sulfotransferase
G6N59_RS18685	COG3119	arylsulfatase activity
G6N59_RS18690	COG0494	nUDIX hydrolase
G6N59_RS18705	COG0671	phosphoesterase, PA-phosphatase related
G6N59_RS18750	COG0640	Transcriptional regulator
G6N59_RS18825	COG2032	superoxide dismutase activity
G6N59_RS18840	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N59_RS18880	COG2181	nitrate reductase activity
G6N59_RS18880	COG0247	lactate metabolic process
G6N59_RS18970	COG2072	flavoprotein involved in K transport
G6N59_RS18980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N59_RS18990	COG0443	Heat shock 70 kDa protein
G6N59_RS18995	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6N59_RS19005	COG0789	Transcriptional regulator
G6N59_RS19010	COG1051	belongs to the nudix hydrolase family
G6N59_RS19015	COG1051	belongs to the nudix hydrolase family
G6N59_RS19060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N59_RS19085	COG0542	response to heat
G6N59_RS19090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N59_RS19115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N59_RS19145	COG0640	Transcriptional regulator
G6N59_RS19155	COG0798	PFAM Bile acid sodium symporter
G6N59_RS19160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N59_RS19195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N59_RS19220	COG0745	RESPONSE REGULATOR receiver
G6N59_RS19225	COG2205	protein histidine kinase activity
G6N59_RS19255	COG2124	cytochrome p450
G6N59_RS19275	COG1012	belongs to the aldehyde dehydrogenase family
G6N59_RS19320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N59_RS19330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N59_RS19340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G6N59_RS19355	COG1309	transcriptional regulator
G6N59_RS19380	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N59_RS19385	COG0047	phosphoribosylformylglycinamidine synthase activity
G6N59_RS19395	COG2837	iron assimilation
G6N59_RS19400	COG1362	aminopeptidase activity
G6N59_RS19450	COG0354	folic acid binding
G6N59_RS19460	COG4044	May play a role in the intracellular transport of hydrophobic ligands
G6N59_RS19470	COG2897	thiosulfate sulfurtransferase activity
G6N59_RS19490	COG0745	RESPONSE REGULATOR receiver
G6N59_RS19495	COG0456	acetyltransferase
G6N59_RS19500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G6N59_RS19510	COG0581	inorganic phosphate transmembrane transporter activity
G6N59_RS19515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6N59_RS19520	COG0745	RESPONSE REGULATOR receiver
G6N59_RS19565	COG2346	COG2346, Truncated hemoglobins
G6N59_RS19590	COG0300	oxidoreductase activity
G6N59_RS19595	COG0789	Transcriptional regulator
G6N59_RS19650	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G6N59_RS19650	COG4447	cellulose binding
G6N59_RS19710	COG1233	COG1233 Phytoene dehydrogenase and related
G6N59_RS19720	COG1953	Uracil, thiamine, allantoin
G6N59_RS19735	COG4266	Belongs to the allantoicase family
G6N59_RS19745	COG0657	acetylesterase activity
G6N59_RS19750	COG0183	Belongs to the thiolase family
G6N59_RS19755	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N59_RS19755	COG1024	Enoyl-CoA hydratase
G6N59_RS19775	COG3467	pyridoxamine 5'-phosphate
G6N59_RS19815	COG1285	pathogenesis
G6N59_RS19825	COG2239	Acts as a magnesium transporter
G6N59_RS19840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS19875	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N59_RS19895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G6N59_RS19900	COG3304	Inner membrane component domain
G6N59_RS19905	COG1278	Cold shock
G6N59_RS19910	COG0435	Glutathione S-transferase
G6N59_RS19920	COG2814	Major facilitator Superfamily
G6N59_RS19985	COG0259	pyridoxamine-phosphate oxidase activity
G6N59_RS20005	COG1846	Transcriptional regulator
G6N59_RS20010	COG0545	Peptidyl-prolyl cis-trans isomerase
G6N59_RS20020	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
G6N59_RS20035	COG2205	protein histidine kinase activity
G6N59_RS20060	COG1132	(ABC) transporter
G6N59_RS20065	COG1132	(ABC) transporter
G6N59_RS20070	COG2197	response regulator
G6N59_RS20075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N59_RS20080	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS20105	COG1012	belongs to the aldehyde dehydrogenase family
G6N59_RS20120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N59_RS20125	COG1309	transcriptional regulator
G6N59_RS20140	COG1024	Enoyl-CoA hydratase
G6N59_RS20150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N59_RS20180	COG0183	Belongs to the thiolase family
G6N59_RS20220	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS20225	COG0471	metal ion transport
G6N59_RS20225	COG0490	domain, Protein
G6N59_RS20230	COG2801	Transposase and inactivated derivatives
G6N59_RS20230	COG3415	Transposase
G6N59_RS20255	COG0640	Transcriptional regulator
G6N59_RS20270	COG0640	Transcriptional regulator
G6N59_RS20280	COG4221	oxidoreductase activity
G6N59_RS20285	COG1012	belongs to the aldehyde dehydrogenase family
G6N59_RS20320	COG2508	Transcriptional regulator
G6N59_RS20335	COG0789	Transcriptional regulator
G6N59_RS20350	COG0693	protein deglycase activity
G6N59_RS20370	COG3486	L-lysine 6-monooxygenase (NADPH) activity
G6N59_RS20380	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G6N59_RS20380	COG1672	PFAM Archaeal ATPase
G6N59_RS20425	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G6N59_RS20430	COG3285	dna ligase
G6N59_RS20430	COG1793	dna ligase
G6N59_RS20435	COG0328	RNA-DNA hybrid ribonuclease activity
G6N59_RS20450	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS20465	COG0477	Major facilitator Superfamily
G6N59_RS20480	COG1950	PFAM Membrane protein of
G6N59_RS20485	COG1289	transmembrane transporter activity
G6N59_RS20490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N59_RS20495	COG1605	Chorismate mutase
G6N59_RS20505	COG0166	Belongs to the GPI family
G6N59_RS20510	COG1605	Chorismate mutase
G6N59_RS20530	COG0045	succinate-CoA ligase (ADP-forming) activity
G6N59_RS20600	COG0579	oxidoreductase
G6N59_RS20615	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
G6N59_RS20640	COG1024	Enoyl-CoA hydratase
G6N59_RS20655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N59_RS20675	COG0745	RESPONSE REGULATOR receiver
G6N59_RS20685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N59_RS20690	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N59_RS20690	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N59_RS20730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6N59_RS20735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6N59_RS20745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N59_RS20760	COG1309	transcriptional regulator
G6N59_RS20795	COG0254	rRNA binding
G6N59_RS20800	COG3345	alpha-galactosidase
G6N59_RS20805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N59_RS20805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N59_RS20810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6N59_RS20845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6N59_RS20860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G6N59_RS20870	COG0084	hydrolase, TatD family'
G6N59_RS20875	COG3583	domain protein
G6N59_RS20885	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G6N59_RS20890	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS20945	COG1309	transcriptional regulator
G6N59_RS20960	COG3956	TIGRFAM MazG family protein
G6N59_RS20970	COG2837	iron assimilation
G6N59_RS20980	COG0672	)-iron permease
G6N59_RS21030	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G6N59_RS21035	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G6N59_RS21055	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS21075	COG2199	diguanylate cyclase activity
G6N59_RS21075	COG2203	Gaf domain
G6N59_RS21160	COG1216	Glycosyl transferase, family 2
G6N59_RS21190	COG2909	trisaccharide binding
G6N59_RS21220	COG4565	transcriptional regulatory protein
G6N59_RS21225	COG3290	protein histidine kinase activity
G6N59_RS21230	COG1301	dicarboxylic acid transport
G6N59_RS21245	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS21255	COG1309	transcriptional regulator
G6N59_RS21260	COG0183	Belongs to the thiolase family
G6N59_RS21265	COG3804	dihydrodipicolinate reductase
G6N59_RS21270	COG1063	alcohol dehydrogenase
G6N59_RS21295	COG1316	TRANSCRIPTIONal
G6N59_RS21325	COG1024	Enoyl-CoA hydratase
G6N59_RS21335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G6N59_RS21345	COG0183	Belongs to the thiolase family
G6N59_RS21350	COG2755	lipolytic protein G-D-S-L family
G6N59_RS21355	COG0657	acetylesterase activity
G6N59_RS21390	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS21415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6N59_RS21425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N59_RS21435	COG1331	Highly conserved protein containing a thioredoxin domain
G6N59_RS21450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G6N59_RS21470	COG0572	uridine kinase
G6N59_RS21480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6N59_RS21490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G6N59_RS21530	COG2205	protein histidine kinase activity
G6N59_RS21535	COG0745	RESPONSE REGULATOR receiver
G6N59_RS21575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6N59_RS21580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N59_RS21590	COG3119	arylsulfatase activity
G6N59_RS21595	COG1716	ATPase activity
G6N59_RS21635	COG0012	GTP binding
G6N59_RS21740	COG2186	Transcriptional regulator
G6N59_RS21745	COG0183	Belongs to the thiolase family
G6N59_RS21750	COG1024	Enoyl-CoA hydratase
G6N59_RS21755	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS21780	COG1024	Enoyl-CoA hydratase
G6N59_RS21785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N59_RS21800	COG2409	Drug exporters of the RND superfamily
G6N59_RS21810	COG2226	methyltransferase
G6N59_RS21815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G6N59_RS21820	COG2188	Transcriptional regulator
G6N59_RS21825	COG2508	Transcriptional regulator
G6N59_RS21830	COG2072	flavoprotein involved in K transport
G6N59_RS21835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G6N59_RS21835	COG2124	cytochrome p450
G6N59_RS21840	COG2233	PERMEase
G6N59_RS21845	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N59_RS21855	COG3467	pyridoxamine 5'-phosphate
G6N59_RS21875	COG1396	sequence-specific DNA binding
G6N59_RS21880	COG0235	Class ii aldolase
G6N59_RS21885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N59_RS21920	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS21935	COG1051	belongs to the nudix hydrolase family
G6N59_RS21940	COG2154	pterin-4-alpha-carbinolamine dehydratase
G6N59_RS21965	COG0747	negative chemotaxis
G6N59_RS21980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N59_RS22005	COG1902	pentaerythritol trinitrate reductase activity
G6N59_RS22005	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N59_RS22010	COG1695	Transcriptional regulator
G6N59_RS22015	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6N59_RS22045	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS22060	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS22065	COG2258	MOSC domain
G6N59_RS22070	COG2171	N-acyltransferase activity
G6N59_RS22085	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS22095	COG1063	alcohol dehydrogenase
G6N59_RS22110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N59_RS22120	COG0488	(ABC) transporter
G6N59_RS22135	COG1611	Belongs to the LOG family
G6N59_RS22140	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS22150	COG0463	Glycosyl transferase, family 2
G6N59_RS22160	COG0519	Catalyzes the synthesis of GMP from XMP
G6N59_RS22170	COG0297	glycogen (starch) synthase activity
G6N59_RS22175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G6N59_RS22210	COG3559	Exporter of polyketide antibiotics
G6N59_RS22215	COG1131	(ABC) transporter
G6N59_RS22220	COG1309	transcriptional regulator
G6N59_RS22235	COG5662	AntiSigma factor
G6N59_RS22240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N59_RS22245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N59_RS22290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N59_RS22310	COG2239	Acts as a magnesium transporter
G6N59_RS22365	COG0598	Magnesium transport protein CorA
G6N59_RS22400	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N59_RS22400	COG0567	Dehydrogenase, E1 component
G6N59_RS22410	COG2814	Major facilitator Superfamily
G6N59_RS22420	COG0277	FAD linked oxidase domain protein
G6N59_RS22475	COG0277	FAD linked oxidase domain protein
G6N59_RS22500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS22650	COG0745	RESPONSE REGULATOR receiver
G6N59_RS22655	COG2205	protein histidine kinase activity
G6N59_RS22660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N59_RS22670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N59_RS22680	COG2814	Major facilitator Superfamily
G6N59_RS22685	COG0175	sulfate reduction
G6N59_RS22765	COG2197	response regulator
G6N59_RS22770	COG4585	Histidine kinase
G6N59_RS22780	COG1473	amidohydrolase
G6N59_RS22805	COG0018	arginyl-trna synthetase
G6N59_RS22810	COG0019	diaminopimelate decarboxylase activity
G6N59_RS22815	COG0460	homoserine dehydrogenase
G6N59_RS22820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G6N59_RS22835	COG1309	transcriptional regulator
G6N59_RS22840	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS22850	COG4941	Belongs to the sigma-70 factor family
G6N59_RS22855	COG0254	rRNA binding
G6N59_RS22860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G6N59_RS22865	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N59_RS22875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G6N59_RS22885	COG0356	it plays a direct role in the translocation of protons across the membrane
G6N59_RS22890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N59_RS22900	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N59_RS22900	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6N59_RS22905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G6N59_RS22910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G6N59_RS22915	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G6N59_RS22920	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G6N59_RS22980	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G6N59_RS22990	COG0346	lactoylglutathione lyase activity
G6N59_RS22995	COG0183	Belongs to the thiolase family
G6N59_RS23000	COG2409	Drug exporters of the RND superfamily
G6N59_RS23010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6N59_RS23015	COG0366	Alpha amylase catalytic
G6N59_RS23020	COG0058	SHG alpha-glucan phosphorylase activity
G6N59_RS23025	COG4257	antibiotic catabolic process
G6N59_RS23030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N59_RS23035	COG1846	Transcriptional regulator
G6N59_RS23045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G6N59_RS23060	COG3191	aminopeptidase activity
G6N59_RS23070	COG1234	tRNA 3'-trailer cleavage
G6N59_RS23075	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6N59_RS23085	COG0730	response to heat
G6N59_RS23095	COG0596	Alpha beta hydrolase
G6N59_RS23145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N59_RS23200	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N59_RS23220	COG4221	oxidoreductase activity
G6N59_RS23260	COG0668	transmembrane transport
G6N59_RS23275	COG1297	OPT oligopeptide transporter protein
G6N59_RS23280	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G6N59_RS23295	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS23320	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS23415	COG1733	regulation of RNA biosynthetic process
G6N59_RS23465	COG2205	protein histidine kinase activity
G6N59_RS23470	COG0745	RESPONSE REGULATOR receiver
G6N59_RS23480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N59_RS23485	COG0183	Belongs to the thiolase family
G6N59_RS23490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N59_RS23495	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G6N59_RS23505	COG1309	transcriptional regulator
G6N59_RS23510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N59_RS23515	COG2267	carboxylic ester hydrolase activity
G6N59_RS23530	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS23560	COG1116	anion transmembrane transporter activity
G6N59_RS23565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6N59_RS23570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N59_RS23575	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6N59_RS23580	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6N59_RS23590	COG3757	hydrolase, family 25
G6N59_RS23615	COG0235	Class ii aldolase
G6N59_RS23625	COG2188	Transcriptional regulator
G6N59_RS23765	COG3547	Transposase (IS116 IS110 IS902 family)
G6N59_RS23880	COG0433	COG0433 Predicted ATPase
G6N59_RS23885	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS23905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N59_RS23915	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS23940	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N59_RS23990	COG2902	Dehydrogenase
G6N59_RS23995	COG0824	Thioesterase
G6N59_RS24040	COG0366	Alpha amylase catalytic
G6N59_RS24060	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G6N59_RS24065	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N59_RS24080	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6N59_RS24105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G6N59_RS24125	COG3239	Fatty acid desaturase
G6N59_RS24140	COG0544	peptidyl-prolyl cis-trans isomerase activity
G6N59_RS24145	COG0740	serine-type endopeptidase activity
G6N59_RS24150	COG0740	serine-type endopeptidase activity
G6N59_RS24165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G6N59_RS24180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N59_RS24190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N59_RS24205	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G6N59_RS24205	COG0674	pyruvate-flavodoxin oxidoreductase activity
G6N59_RS24210	COG1013	pyruvate-flavodoxin oxidoreductase activity
G6N59_RS24215	COG0746	molybdenum cofactor guanylyltransferase activity
G6N59_RS24220	COG1388	LysM domain
G6N59_RS24225	COG0596	Alpha beta hydrolase
G6N59_RS24230	COG0823	Involved in the tonB-independent uptake of proteins
G6N59_RS24230	COG1506	peptidase
G6N59_RS24235	COG3268	Saccharopine dehydrogenase
G6N59_RS24245	COG0525	valine-tRNA ligase activity
G6N59_RS24250	COG0285	dihydrofolate synthase activity
G6N59_RS24260	COG0105	UTP biosynthetic process
G6N59_RS24265	COG1530	ribonuclease E activity
G6N59_RS24280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6N59_RS24285	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G6N59_RS24290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N59_RS24295	COG2072	flavoprotein involved in K transport
G6N59_RS24320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N59_RS24325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G6N59_RS24330	COG0542	response to heat
G6N59_RS24340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G6N59_RS24345	COG0799	negative regulation of ribosome biogenesis
G6N59_RS24350	COG0406	alpha-ribazole phosphatase activity
G6N59_RS24355	COG2755	lipolytic protein G-D-S-L family
G6N59_RS24370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N59_RS24385	COG0174	glutamine synthetase
G6N59_RS24410	COG1305	Transglutaminase-like
G6N59_RS24415	COG0517	IMP dehydrogenase activity
G6N59_RS24415	COG0516	GMP reductase activity
G6N59_RS24435	COG2020	methyltransferase activity
G6N59_RS24440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N59_RS24455	COG3387	PFAM Glycoside hydrolase 15-related
G6N59_RS24465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G6N59_RS24470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G6N59_RS24475	COG4208	sulfate ABC transporter
G6N59_RS24485	COG1045	serine acetyltransferase
G6N59_RS24495	COG3158	transport of potassium into the cell
G6N59_RS24520	COG1169	isochorismate synthase
G6N59_RS24540	COG1021	2,3-dihydroxybenzoate-AMP ligase
G6N59_RS24545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N59_RS24545	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G6N59_RS24595	COG1420	regulation of RNA biosynthetic process
G6N59_RS24600	COG0484	heat shock protein binding
G6N59_RS24670	COG0494	nUDIX hydrolase
G6N59_RS24685	COG0423	glycine-tRNA ligase activity
G6N59_RS24705	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G6N59_RS24710	COG0358	DNA primase activity
G6N59_RS24775	COG1175	transmembrane transport
G6N59_RS24800	COG1403	HNH endonuclease
G6N59_RS24905	COG1063	alcohol dehydrogenase
G6N59_RS24940	COG0058	SHG alpha-glucan phosphorylase activity
G6N59_RS24945	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS24955	COG1802	Transcriptional regulator
G6N59_RS24960	COG3265	gluconokinase activity
G6N59_RS24975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N59_RS24990	COG2252	PERMEase
G6N59_RS25020	COG1309	transcriptional regulator
G6N59_RS25050	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS25075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N59_RS25080	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G6N59_RS25170	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G6N59_RS25220	COG2197	response regulator
G6N59_RS25225	COG2197	response regulator
G6N59_RS25235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N59_RS25260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N59_RS25315	COG1396	sequence-specific DNA binding
G6N59_RS25320	COG0492	ferredoxin-NADP+ reductase activity
G6N59_RS25345	COG1024	Enoyl-CoA hydratase
G6N59_RS25375	COG4638	Rieske (2fe-2S)
G6N59_RS25380	COG0174	glutamine synthetase
G6N59_RS25385	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G6N59_RS25395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS25400	COG2259	Doxx family
G6N59_RS25415	COG0174	glutamine synthetase
G6N59_RS25435	COG0321	lipoyl(octanoyl) transferase activity
G6N59_RS25465	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6N59_RS25470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6N59_RS25475	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G6N59_RS25480	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G6N59_RS25510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N59_RS25540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G6N59_RS25555	COG1845	cytochrome c oxidase, subunit III
G6N59_RS25585	COG0438	transferase activity, transferring glycosyl groups
G6N59_RS25605	COG0003	Pfam Anion-transporting ATPase
G6N59_RS25620	COG5650	phosphatidylinositol metabolic process
G6N59_RS25685	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G6N59_RS25730	COG0275	rRNA processing
G6N59_RS25740	COG0768	penicillin binding
G6N59_RS25770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6N59_RS25775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G6N59_RS25780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G6N59_RS25785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G6N59_RS25810	COG3599	regulation of cell shape
G6N59_RS25825	COG2186	Transcriptional regulator
G6N59_RS25835	COG0243	molybdopterin cofactor binding
G6N59_RS25875	COG2801	Transposase and inactivated derivatives
G6N59_RS25875	COG3415	Transposase
G6N59_RS25915	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS25925	COG1012	belongs to the aldehyde dehydrogenase family
G6N59_RS25930	COG0183	Belongs to the thiolase family
G6N59_RS25945	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS25950	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS25955	COG2267	carboxylic ester hydrolase activity
G6N59_RS25960	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS26015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N59_RS26030	COG0167	dihydroorotate dehydrogenase activity
G6N59_RS26050	COG1968	undecaprenyl-diphosphatase activity
G6N59_RS26080	COG1218	3'(2'),5'-bisphosphate nucleotidase
G6N59_RS26090	COG2351	hydroxyisourate hydrolase activity
G6N59_RS26115	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6N59_RS26120	COG0590	tRNA wobble adenosine to inosine editing
G6N59_RS26140	COG0215	cysteine-tRNA ligase activity
G6N59_RS26145	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS26160	COG0646	methionine synthase
G6N59_RS26160	COG1410	methionine synthase
G6N59_RS26170	COG0477	Major facilitator Superfamily
G6N59_RS26180	COG0140	phosphoribosyl-ATP diphosphatase activity
G6N59_RS26185	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G6N59_RS26195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6N59_RS26200	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6N59_RS26240	COG2814	Major facilitator Superfamily
G6N59_RS26250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N59_RS26315	COG4122	O-methyltransferase activity
G6N59_RS26325	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N59_RS26330	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N59_RS26340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N59_RS26345	COG2957	Belongs to the agmatine deiminase family
G6N59_RS26360	COG2902	Dehydrogenase
G6N59_RS26370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G6N59_RS26380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N59_RS26420	COG1937	Protein conserved in bacteria
G6N59_RS26425	COG2140	Oxalate decarboxylase
G6N59_RS26455	COG2378	regulation of single-species biofilm formation
G6N59_RS26495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N59_RS26500	COG2226	methyltransferase
G6N59_RS26510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G6N59_RS26540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6N59_RS26560	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6N59_RS26590	COG0440	acetolactate synthase activity
G6N59_RS26600	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6N59_RS26615	COG0473	3-isopropylmalate dehydrogenase activity
G6N59_RS26655	COG2271	Major facilitator Superfamily
G6N59_RS26665	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N59_RS26670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N59_RS26700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6N59_RS26720	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G6N59_RS26725	COG1920	GTP binding
G6N59_RS26735	COG0626	cystathionine gamma-synthase activity
G6N59_RS26755	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G6N59_RS26765	COG1461	Dihydroxyacetone kinase
G6N59_RS26770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G6N59_RS26785	COG0656	L-ascorbic acid biosynthetic process
G6N59_RS26790	COG0656	L-ascorbic acid biosynthetic process
G6N59_RS26815	COG0742	ribosomal rna small subunit methyltransferase
G6N59_RS26820	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G6N59_RS26825	COG3599	regulation of cell shape
G6N59_RS26840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N59_RS26865	COG1254	Belongs to the acylphosphatase family
G6N59_RS26890	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G6N59_RS26895	COG3383	formate dehydrogenase (NAD+) activity
G6N59_RS26900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G6N59_RS26910	COG1686	Belongs to the peptidase S11 family
G6N59_RS26915	COG1686	Belongs to the peptidase S11 family
G6N59_RS26995	COG1053	succinate dehydrogenase
G6N59_RS27010	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS27015	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS27030	COG1113	amino acid transport
G6N59_RS27055	COG1414	Transcriptional regulator
G6N59_RS27065	COG0346	lactoylglutathione lyase activity
G6N59_RS27080	COG2072	flavoprotein involved in K transport
G6N59_RS27085	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS27100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N59_RS27110	COG0028	Belongs to the TPP enzyme family
G6N59_RS27120	COG0792	nuclease activity
G6N59_RS27190	COG0052	Belongs to the universal ribosomal protein uS2 family
G6N59_RS27195	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G6N59_RS27225	COG0154	amidase activity
G6N59_RS27235	COG0754	glutathionylspermidine amidase activity
G6N59_RS27260	COG0233	cytoplasmic translational termination
G6N59_RS27265	COG0575	Belongs to the CDS family
G6N59_RS27275	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G6N59_RS27295	COG0659	secondary active sulfate transmembrane transporter activity
G6N59_RS27305	COG2837	iron assimilation
G6N59_RS27315	COG3842	ATPase activity
G6N59_RS27325	COG1840	ABC-type Fe3 transport system, periplasmic component
G6N59_RS27355	COG0750	zinc metalloprotease
G6N59_RS27365	COG0454	-acetyltransferase
G6N59_RS27365	COG0456	acetyltransferase
G6N59_RS27385	COG1492	cobalamin metabolic process
G6N59_RS27400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6N59_RS27405	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
G6N59_RS27445	COG1648	precorrin-2 dehydrogenase activity
G6N59_RS27445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N59_RS27455	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N59_RS27470	COG0442	prolyl-tRNA aminoacylation
G6N59_RS27485	COG0779	Required for maturation of 30S ribosomal subunits
G6N59_RS27490	COG0195	Participates in both transcription termination and antitermination
G6N59_RS27510	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G6N59_RS27520	COG1024	Enoyl-CoA hydratase
G6N59_RS27560	COG0667	Aldo Keto reductase
G6N59_RS27580	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G6N59_RS27585	COG1185	polyribonucleotide nucleotidyltransferase activity
G6N59_RS27600	COG0686	Belongs to the AlaDH PNT family
G6N59_RS27610	COG1309	transcriptional regulator
G6N59_RS27625	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N59_RS27690	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G6N59_RS27700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6N59_RS27705	COG0187	DNA topoisomerase II activity
G6N59_RS27710	COG3214	Protein conserved in bacteria
G6N59_RS27725	COG0531	amino acid
G6N59_RS27730	COG2267	carboxylic ester hydrolase activity
G6N59_RS27740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N59_RS27745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G6N59_RS27750	COG1309	transcriptional regulator
G6N59_RS27760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N59_RS27795	COG1674	ftsk spoiiie
G6N59_RS27805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G6N59_RS27815	COG1396	sequence-specific DNA binding
G6N59_RS27835	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
G6N59_RS27850	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS27855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G6N59_RS27860	COG2137	regulation of response to DNA damage stimulus
G6N59_RS27870	COG1028	Short-chain dehydrogenase reductase Sdr
G6N59_RS27880	COG0765	amino acid transport
G6N59_RS27885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N59_RS27890	COG1126	abc transporter atp-binding protein
G6N59_RS27895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6N59_RS27905	COG1196	nuclear chromosome segregation
G6N59_RS27915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G6N59_RS27920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G6N59_RS27925	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6N59_RS27935	COG0513	Belongs to the DEAD box helicase family
G6N59_RS27940	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS27950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6N59_RS27955	COG1388	LysM domain
G6N59_RS28025	COG0406	alpha-ribazole phosphatase activity
G6N59_RS28045	COG0483	inositol monophosphate 1-phosphatase activity
G6N59_RS28065	COG0756	dUTP diphosphatase activity
G6N59_RS28095	COG0569	domain protein
G6N59_RS28100	COG0531	amino acid
G6N59_RS28105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6N59_RS28110	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G6N59_RS28115	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G6N59_RS28150	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G6N59_RS28175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N59_RS28350	COG0596	Alpha beta hydrolase
G6N59_RS28350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N59_RS28350	COG2226	methyltransferase
G6N59_RS28355	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G6N59_RS28485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G6N59_RS28515	COG1404	Belongs to the peptidase S8 family
G6N59_RS28660	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS28785	COG1609	Transcriptional regulator
G6N59_RS28870	COG0328	RNA-DNA hybrid ribonuclease activity
G6N59_RS28925	COG1309	transcriptional regulator
G6N59_RS29025	COG0789	Transcriptional regulator
G6N59_RS29050	COG1116	anion transmembrane transporter activity
G6N59_RS29055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N59_RS29070	COG1914	H( )-stimulated, divalent metal cation uptake system
G6N59_RS29085	COG2239	Acts as a magnesium transporter
G6N59_RS29115	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G6N59_RS29225	COG0464	growth
G6N59_RS29265	COG0789	Transcriptional regulator
G6N59_RS29300	COG0701	Predicted permease
G6N59_RS29305	COG2132	Multicopper oxidase
G6N59_RS29330	COG0745	RESPONSE REGULATOR receiver
G6N59_RS29375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N59_RS29385	COG0726	polysaccharide deacetylase
G6N59_RS29425	COG0745	RESPONSE REGULATOR receiver
G6N59_RS29435	COG1376	ErfK ybiS ycfS ynhG family protein
G6N59_RS29440	COG2205	protein histidine kinase activity
G6N59_RS29445	COG0671	phosphoesterase, PA-phosphatase related
G6N59_RS29500	COG2226	methyltransferase
G6N59_RS29645	COG0789	Transcriptional regulator
G6N59_RS29715	COG0789	Transcriptional regulator
G6N59_RS29875	COG1192	Involved in chromosome partitioning
G6N59_RS30070	COG1404	Belongs to the peptidase S8 family
G6N59_RS30160	COG1309	transcriptional regulator
G6N59_RS30190	COG1024	Enoyl-CoA hydratase
G6N59_RS30190	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N59_RS30195	COG1309	transcriptional regulator
G6N59_RS30205	COG3328	transposase activity
G6N59_RS30250	COG0633	Ferredoxin
G6N59_RS30270	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS30320	COG2072	flavoprotein involved in K transport
G6N59_RS30325	COG2072	flavoprotein involved in K transport
G6N59_RS30335	COG2072	flavoprotein involved in K transport
G6N59_RS30350	COG0318	PFAM AMP-dependent synthetase and ligase
G6N59_RS30355	COG1960	acyl-CoA dehydrogenase activity
G6N59_RS30475	COG0464	growth