locus-tag	class	description
G6N52_RS00010	COG0714	Associated with various cellular activities
G6N52_RS00025	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
G6N52_RS00055	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS00060	COG2124	cytochrome p450
G6N52_RS00120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS00135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N52_RS00145	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G6N52_RS00170	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G6N52_RS00175	COG4842	Belongs to the WXG100 family
G6N52_RS00190	COG1674	ftsk spoiiie
G6N52_RS00200	COG1404	Belongs to the peptidase S8 family
G6N52_RS00210	COG0142	geranyltranstransferase activity
G6N52_RS00235	COG3268	Saccharopine dehydrogenase
G6N52_RS00270	COG0203	ribosomal protein L17
G6N52_RS00290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G6N52_RS00295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G6N52_RS00300	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G6N52_RS00325	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G6N52_RS00335	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS00360	COG0563	adenylate kinase activity
G6N52_RS00370	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N52_RS00375	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N52_RS00380	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N52_RS00385	COG0477	Major facilitator Superfamily
G6N52_RS00390	COG0616	signal peptide processing
G6N52_RS00400	COG0200	Binds to the 23S rRNA
G6N52_RS00410	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G6N52_RS00415	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G6N52_RS00420	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G6N52_RS00425	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G6N52_RS00430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6N52_RS00435	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G6N52_RS00440	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G6N52_RS00445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G6N52_RS00455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G6N52_RS00470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G6N52_RS00475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G6N52_RS00480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G6N52_RS00485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G6N52_RS00495	COG0088	Forms part of the polypeptide exit tunnel
G6N52_RS00500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G6N52_RS00505	COG0051	transcription antitermination factor activity, RNA binding
G6N52_RS00515	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N52_RS00545	COG0477	Major facilitator Superfamily
G6N52_RS00575	COG0535	radical SAM domain protein
G6N52_RS00595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G6N52_RS00610	COG1834	amidinotransferase
G6N52_RS00620	COG2235	arginine
G6N52_RS00635	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G6N52_RS00670	COG1024	Enoyl-CoA hydratase
G6N52_RS00680	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6N52_RS00695	COG0085	RNA polymerase activity
G6N52_RS00715	COG0222	ribosome binding
G6N52_RS00720	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G6N52_RS00745	COG2318	DinB family
G6N52_RS00760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N52_RS00765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N52_RS00775	COG0081	regulation of translation
G6N52_RS00790	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G6N52_RS00805	COG2030	dehydratase
G6N52_RS00815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G6N52_RS00835	COG1959	2 iron, 2 sulfur cluster binding
G6N52_RS00840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N52_RS00900	COG2030	dehydratase
G6N52_RS00905	COG2030	dehydratase
G6N52_RS00920	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS00940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N52_RS00970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS00975	COG1063	alcohol dehydrogenase
G6N52_RS00980	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS00985	COG2072	flavoprotein involved in K transport
G6N52_RS00995	COG2072	flavoprotein involved in K transport
G6N52_RS01020	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS01030	COG1902	pentaerythritol trinitrate reductase activity
G6N52_RS01045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS01050	COG2072	flavoprotein involved in K transport
G6N52_RS01055	COG0183	Belongs to the thiolase family
G6N52_RS01060	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N52_RS01060	COG1024	Enoyl-CoA hydratase
G6N52_RS01070	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS01075	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS01080	COG0406	alpha-ribazole phosphatase activity
G6N52_RS01095	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS01115	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS01125	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS01135	COG1024	Enoyl-CoA hydratase
G6N52_RS01150	COG1595	DNA-templated transcription, initiation
G6N52_RS01210	COG1666	GTP binding
G6N52_RS01215	COG2072	flavoprotein involved in K transport
G6N52_RS01235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS01285	COG0501	Belongs to the peptidase M48B family
G6N52_RS01295	COG0644	oxidoreductase
G6N52_RS01310	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS01315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS01370	COG4221	oxidoreductase activity
G6N52_RS01375	COG0438	transferase activity, transferring glycosyl groups
G6N52_RS01390	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G6N52_RS01405	COG4977	sequence-specific DNA binding
G6N52_RS01410	COG4948	Mandelate Racemase Muconate Lactonizing
G6N52_RS01415	COG0277	FAD linked oxidase domain protein
G6N52_RS01415	COG0247	lactate metabolic process
G6N52_RS01425	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS01440	COG0546	phosphoglycolate phosphatase activity
G6N52_RS01450	COG4221	oxidoreductase activity
G6N52_RS01475	COG0745	RESPONSE REGULATOR receiver
G6N52_RS01485	COG2070	2-Nitropropane dioxygenase
G6N52_RS01490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G6N52_RS01525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N52_RS01535	COG0785	Cytochrome C biogenesis protein
G6N52_RS01545	COG0406	alpha-ribazole phosphatase activity
G6N52_RS01550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G6N52_RS01625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N52_RS01630	COG0181	hydroxymethylbilane synthase activity
G6N52_RS01635	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G6N52_RS01650	COG2030	dehydratase
G6N52_RS01710	COG0745	RESPONSE REGULATOR receiver
G6N52_RS01715	COG5002	protein histidine kinase activity
G6N52_RS01800	COG2733	membrane
G6N52_RS01810	COG2326	polyphosphate kinase activity
G6N52_RS01815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N52_RS01870	COG1505	serine-type exopeptidase activity
G6N52_RS01935	COG1511	domain protein
G6N52_RS01950	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N52_RS01970	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G6N52_RS01975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6N52_RS01980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6N52_RS01985	COG0477	Major facilitator Superfamily
G6N52_RS01990	COG0459	protein refolding
G6N52_RS02000	COG0129	dihydroxy-acid dehydratase activity
G6N52_RS02010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N52_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS02020	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6N52_RS02030	COG1129	ABC transporter
G6N52_RS02055	COG2337	Toxic component of a toxin-antitoxin (TA) module
G6N52_RS02070	COG0647	UMP catabolic process
G6N52_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS02100	COG0688	phosphatidylethanolamine metabolic process
G6N52_RS02110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N52_RS02115	COG2111	Na H antiporter
G6N52_RS02115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6N52_RS02135	COG2212	antiporter activity
G6N52_RS02140	COG1320	monovalent cation:proton antiporter activity
G6N52_RS02155	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G6N52_RS02180	COG0242	peptide deformylase activity
G6N52_RS02220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N52_RS02240	COG1403	HNH endonuclease
G6N52_RS02245	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G6N52_RS02250	COG0351	phosphomethylpyrimidine kinase
G6N52_RS02260	COG2072	flavoprotein involved in K transport
G6N52_RS02270	COG2239	Acts as a magnesium transporter
G6N52_RS02295	COG1309	transcriptional regulator
G6N52_RS02305	COG2234	aminopeptidase activity
G6N52_RS02315	COG2022	thiamine diphosphate biosynthetic process
G6N52_RS02325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N52_RS02330	COG0352	thiamine-phosphate diphosphorylase activity
G6N52_RS02345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N52_RS02350	COG0515	serine threonine protein kinase
G6N52_RS02365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS02370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N52_RS02405	COG2409	Drug exporters of the RND superfamily
G6N52_RS02435	COG1994	Peptidase M50
G6N52_RS02460	COG2902	Dehydrogenase
G6N52_RS02465	COG3328	transposase activity
G6N52_RS02490	COG0726	polysaccharide deacetylase
G6N52_RS02500	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS02505	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS02525	COG2066	Belongs to the glutaminase family
G6N52_RS02530	COG0174	glutamine synthetase
G6N52_RS02535	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G6N52_RS02540	COG1304	FMN binding
G6N52_RS02545	COG1609	Transcriptional regulator
G6N52_RS02555	COG0586	Pfam SNARE associated Golgi protein
G6N52_RS02580	COG3608	succinylglutamate desuccinylase aspartoacylase
G6N52_RS02580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G6N52_RS02680	COG0542	response to heat
G6N52_RS02710	COG0789	Transcriptional regulator
G6N52_RS02715	COG0484	heat shock protein binding
G6N52_RS02720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6N52_RS02725	COG0443	Heat shock 70 kDa protein
G6N52_RS02735	COG2267	carboxylic ester hydrolase activity
G6N52_RS02740	COG1309	transcriptional regulator
G6N52_RS02770	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
G6N52_RS02830	COG0247	lactate metabolic process
G6N52_RS02830	COG2181	nitrate reductase activity
G6N52_RS02855	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N52_RS02890	COG0657	acetylesterase activity
G6N52_RS02910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N52_RS03010	COG1404	Belongs to the peptidase S8 family
G6N52_RS03050	COG3266	domain, Protein
G6N52_RS03055	COG0464	growth
G6N52_RS03090	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS03095	COG1801	Protein of unknown function DUF72
G6N52_RS03100	COG1573	uracil-dna glycosylase
G6N52_RS03105	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS03120	COG2354	Protein conserved in bacteria
G6N52_RS03125	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS03135	COG3384	dioxygenase
G6N52_RS03160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N52_RS03175	COG0714	Associated with various cellular activities
G6N52_RS03230	COG1309	transcriptional regulator
G6N52_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS03250	COG2855	membrane
G6N52_RS03270	COG1984	allophanate hydrolase subunit 2
G6N52_RS03300	COG2146	nitrite reductase [NAD(P)H] activity
G6N52_RS03305	COG2146	nitrite reductase [NAD(P)H] activity
G6N52_RS03305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N52_RS03315	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G6N52_RS03330	COG1053	succinate dehydrogenase
G6N52_RS03355	COG5651	PPE family
G6N52_RS03360	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS03380	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N52_RS03385	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS03390	COG0183	Belongs to the thiolase family
G6N52_RS03395	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS03400	COG2030	dehydratase
G6N52_RS03405	COG1309	transcriptional regulator
G6N52_RS03410	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N52_RS03415	COG0589	response to stress
G6N52_RS03425	COG4981	capsule polysaccharide biosynthetic process
G6N52_RS03455	COG0297	glycogen (starch) synthase activity
G6N52_RS03460	COG0500	methyltransferase
G6N52_RS03470	COG0183	Belongs to the thiolase family
G6N52_RS03480	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS03495	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS03510	COG1024	Enoyl-CoA hydratase
G6N52_RS03540	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS03545	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS03550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G6N52_RS03570	COG4221	oxidoreductase activity
G6N52_RS03580	COG1024	Enoyl-CoA hydratase
G6N52_RS03625	COG2409	Drug exporters of the RND superfamily
G6N52_RS03645	COG2205	protein histidine kinase activity
G6N52_RS03665	COG2409	Drug exporters of the RND superfamily
G6N52_RS03675	COG1832	CoA-binding protein
G6N52_RS03690	COG3590	peptidase
G6N52_RS03695	COG1376	ErfK ybiS ycfS ynhG family protein
G6N52_RS03700	COG2814	Major facilitator Superfamily
G6N52_RS03710	COG1937	Protein conserved in bacteria
G6N52_RS03735	COG4122	O-methyltransferase activity
G6N52_RS03750	COG1063	alcohol dehydrogenase
G6N52_RS03760	COG2267	carboxylic ester hydrolase activity
G6N52_RS03775	COG0039	L-malate dehydrogenase activity
G6N52_RS03805	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS03815	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS03825	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS03855	COG1403	HNH endonuclease
G6N52_RS03895	COG0300	oxidoreductase activity
G6N52_RS03900	COG3619	membrane
G6N52_RS03930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N52_RS03960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS03970	COG1802	Transcriptional regulator
G6N52_RS03985	COG1309	transcriptional regulator
G6N52_RS04000	COG4716	Myosin-crossreactive antigen
G6N52_RS04020	COG1024	Enoyl-CoA hydratase
G6N52_RS04020	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N52_RS04030	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G6N52_RS04035	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G6N52_RS04040	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS04045	COG2365	Tyrosine phosphatase family
G6N52_RS04050	COG5651	PPE family
G6N52_RS04050	COG3391	amine dehydrogenase activity
G6N52_RS04065	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS04070	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS04075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N52_RS04105	COG1741	Belongs to the pirin family
G6N52_RS04110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N52_RS04120	COG1105	Belongs to the carbohydrate kinase PfkB family
G6N52_RS04125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6N52_RS04125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6N52_RS04125	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G6N52_RS04140	COG2217	Heavy metal translocating P-type atpase
G6N52_RS04150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G6N52_RS04155	COG0783	Belongs to the Dps family
G6N52_RS04175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6N52_RS04215	COG1309	transcriptional regulator
G6N52_RS04240	COG3180	Ammonia monooxygenase
G6N52_RS04295	COG1802	Transcriptional regulator
G6N52_RS04320	COG1063	alcohol dehydrogenase
G6N52_RS04330	COG1403	HNH endonuclease
G6N52_RS04345	COG1335	isochorismatase
G6N52_RS04400	COG2807	transmembrane transport
G6N52_RS04455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N52_RS04540	COG0704	Plays a role in the regulation of phosphate uptake
G6N52_RS04585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS04615	COG0601	transmembrane transport
G6N52_RS04640	COG1846	Transcriptional regulator
G6N52_RS04670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6N52_RS04675	COG1074	ATP-dependent DNA helicase activity
G6N52_RS04680	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G6N52_RS04710	COG1716	ATPase activity
G6N52_RS04715	COG3842	ATPase activity
G6N52_RS04735	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N52_RS04755	COG2124	cytochrome p450
G6N52_RS04765	COG2814	Major facilitator Superfamily
G6N52_RS04770	COG0351	phosphomethylpyrimidine kinase
G6N52_RS04800	COG2124	cytochrome p450
G6N52_RS04835	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS04845	COG0598	Magnesium transport protein CorA
G6N52_RS04850	COG1376	ErfK ybiS ycfS ynhG family protein
G6N52_RS04865	COG1982	Orn Lys Arg decarboxylase major
G6N52_RS04885	COG1309	transcriptional regulator
G6N52_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS04915	COG0477	Major facilitator Superfamily
G6N52_RS04925	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G6N52_RS04930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N52_RS04940	COG1609	Transcriptional regulator
G6N52_RS04960	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS04965	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS04975	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS04985	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS04990	COG2072	flavoprotein involved in K transport
G6N52_RS05005	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS05015	COG2188	Transcriptional regulator
G6N52_RS05020	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS05030	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS05055	COG1309	transcriptional regulator
G6N52_RS05075	COG3383	formate dehydrogenase (NAD+) activity
G6N52_RS05100	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS05105	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS05110	COG2124	cytochrome p450
G6N52_RS05125	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS05185	COG1643	Atp-dependent helicase
G6N52_RS05195	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS05200	COG2124	cytochrome p450
G6N52_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS05225	COG0714	Associated with various cellular activities
G6N52_RS05235	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS05240	COG0523	cobalamin synthesis protein
G6N52_RS05250	COG1309	transcriptional regulator
G6N52_RS05265	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N52_RS05295	COG1309	transcriptional regulator
G6N52_RS05345	COG1309	transcriptional regulator
G6N52_RS05370	COG0367	asparagine synthase
G6N52_RS05405	COG0714	Associated with various cellular activities
G6N52_RS05420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N52_RS05420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N52_RS05455	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N52_RS05485	COG2271	Major facilitator Superfamily
G6N52_RS05490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS05505	COG1473	amidohydrolase
G6N52_RS05535	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS05550	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS05555	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS05570	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS05580	COG1024	Enoyl-CoA hydratase
G6N52_RS05590	COG2124	cytochrome p450
G6N52_RS05595	COG1024	Enoyl-CoA hydratase
G6N52_RS05600	COG2186	Transcriptional regulator
G6N52_RS05605	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS05615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N52_RS05625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS05630	COG1609	Transcriptional regulator
G6N52_RS05680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS05700	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS05705	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS05710	COG1408	metallophosphoesterase
G6N52_RS05715	COG4106	trans-aconitate 2-methyltransferase activity
G6N52_RS05720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N52_RS05725	COG0494	nUDIX hydrolase
G6N52_RS05735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G6N52_RS05740	COG1819	glycosyl
G6N52_RS05750	COG0640	Transcriptional regulator
G6N52_RS05755	COG0346	lactoylglutathione lyase activity
G6N52_RS05780	COG0477	Major facilitator Superfamily
G6N52_RS05790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6N52_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS05805	COG0604	alcohol dehydrogenase
G6N52_RS05805	COG3321	synthase
G6N52_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS05830	COG0778	Nitroreductase
G6N52_RS05845	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
G6N52_RS05855	COG1492	cobalamin metabolic process
G6N52_RS05865	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS05975	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G6N52_RS06000	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N52_RS06005	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06010	COG2124	cytochrome p450
G6N52_RS06025	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS06075	COG0069	glutamate synthase activity
G6N52_RS06155	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06180	COG2197	response regulator
G6N52_RS06185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N52_RS06190	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G6N52_RS06220	COG1376	ErfK ybiS ycfS ynhG family protein
G6N52_RS06230	COG2267	carboxylic ester hydrolase activity
G6N52_RS06240	COG2072	flavoprotein involved in K transport
G6N52_RS06255	COG0346	lactoylglutathione lyase activity
G6N52_RS06285	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06290	COG2072	flavoprotein involved in K transport
G6N52_RS06295	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06330	COG1053	succinate dehydrogenase
G6N52_RS06360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N52_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06410	COG1122	ATPase activity
G6N52_RS06415	COG1268	BioY protein
G6N52_RS06430	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N52_RS06445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6N52_RS06450	COG1120	ATPase activity
G6N52_RS06535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N52_RS06550	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06565	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06585	COG4638	Rieske (2fe-2S)
G6N52_RS06595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS06605	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS06610	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS06615	COG1902	pentaerythritol trinitrate reductase activity
G6N52_RS06625	COG3467	pyridoxamine 5'-phosphate
G6N52_RS06635	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G6N52_RS06640	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N52_RS06690	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G6N52_RS06695	COG2072	flavoprotein involved in K transport
G6N52_RS06700	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06710	COG1115	amino acid carrier protein
G6N52_RS06725	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
G6N52_RS06785	COG0187	DNA topoisomerase II activity
G6N52_RS06790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6N52_RS06820	COG3757	hydrolase, family 25
G6N52_RS06830	COG1396	sequence-specific DNA binding
G6N52_RS06835	COG0235	Class ii aldolase
G6N52_RS06840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N52_RS06895	COG0559	Belongs to the binding-protein-dependent transport system permease family
G6N52_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS06970	COG0028	Belongs to the TPP enzyme family
G6N52_RS06975	COG0069	glutamate synthase activity
G6N52_RS07010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N52_RS07025	COG0028	Belongs to the TPP enzyme family
G6N52_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS07110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N52_RS07125	COG2124	cytochrome p450
G6N52_RS07145	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS07155	COG0702	epimerase
G6N52_RS07160	COG1309	transcriptional regulator
G6N52_RS07170	COG0702	epimerase
G6N52_RS07195	COG4584	PFAM Integrase catalytic
G6N52_RS07205	COG0305	Participates in initiation and elongation during chromosome replication
G6N52_RS07210	COG0359	binds to the 23S rRNA
G6N52_RS07215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G6N52_RS07225	COG0360	Binds together with S18 to 16S ribosomal RNA
G6N52_RS07235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N52_RS07255	COG1260	myo-inositol-1-phosphate synthase
G6N52_RS07275	COG0765	amino acid transport
G6N52_RS07280	COG1126	abc transporter atp-binding protein
G6N52_RS07295	COG4221	oxidoreductase activity
G6N52_RS07300	COG0495	leucyl-tRNA aminoacylation
G6N52_RS07340	COG1678	Uncharacterized ACR, COG1678
G6N52_RS07380	COG1595	DNA-templated transcription, initiation
G6N52_RS07400	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N52_RS07400	COG3409	Peptidoglycan-binding domain 1 protein
G6N52_RS07415	COG1192	Involved in chromosome partitioning
G6N52_RS07420	COG0357	Ribosomal RNA small subunit methyltransferase G
G6N52_RS07430	COG0706	membrane insertase activity
G6N52_RS07435	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G6N52_RS07455	COG0592	DNA-directed DNA polymerase activity
G6N52_RS07460	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G6N52_RS07465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6N52_RS07470	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G6N52_RS07475	COG0187	DNA topoisomerase II activity
G6N52_RS07480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6N52_RS07480	COG1372	Participates in initiation and elongation during chromosome replication
G6N52_RS07540	COG0515	serine threonine protein kinase
G6N52_RS07545	COG0768	penicillin binding
G6N52_RS07560	COG1716	ATPase activity
G6N52_RS07565	COG1716	ATPase activity
G6N52_RS07585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N52_RS07590	COG4521	taurine ABC transporter
G6N52_RS07595	COG1116	anion transmembrane transporter activity
G6N52_RS07620	COG3842	ATPase activity
G6N52_RS07625	COG0588	phosphoglycerate mutase activity
G6N52_RS07630	COG1228	amidohydrolase
G6N52_RS07680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6N52_RS07700	COG0640	Transcriptional regulator
G6N52_RS07725	COG4585	Histidine kinase
G6N52_RS07750	COG0791	NLP P60 protein
G6N52_RS07750	COG3883	PFAM NLP P60 protein
G6N52_RS07820	COG2894	cell division
G6N52_RS07830	COG1404	Belongs to the peptidase S8 family
G6N52_RS07855	COG3328	transposase activity
G6N52_RS07865	COG0067	glutamate synthase
G6N52_RS07865	COG0069	glutamate synthase activity
G6N52_RS07865	COG0070	glutamate synthase
G6N52_RS07880	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G6N52_RS07880	COG1796	DNA polymerase
G6N52_RS07890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G6N52_RS07895	COG1309	transcriptional regulator
G6N52_RS07900	COG2072	flavoprotein involved in K transport
G6N52_RS07910	COG0789	Transcriptional regulator
G6N52_RS07955	COG2119	membrane
G6N52_RS07990	COG1528	Iron-storage protein
G6N52_RS07995	COG1528	Iron-storage protein
G6N52_RS08000	COG1316	TRANSCRIPTIONal
G6N52_RS08055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G6N52_RS08055	COG2146	nitrite reductase [NAD(P)H] activity
G6N52_RS08060	COG0204	Acyl-transferase
G6N52_RS08070	COG0561	phosphatase activity
G6N52_RS08090	COG1216	Glycosyl transferase, family 2
G6N52_RS08095	COG0671	phosphoesterase, PA-phosphatase related
G6N52_RS08105	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N52_RS08115	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N52_RS08145	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N52_RS08155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N52_RS08165	COG2207	Transcriptional regulator
G6N52_RS08165	COG1609	Transcriptional regulator
G6N52_RS08215	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS08220	COG0277	FAD linked oxidase domain protein
G6N52_RS08250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N52_RS08255	COG0154	amidase activity
G6N52_RS08265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N52_RS08270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N52_RS08290	COG1216	Glycosyl transferase, family 2
G6N52_RS08340	COG3220	belongs to the UPF0276 family
G6N52_RS08370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N52_RS08415	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS08435	COG0745	RESPONSE REGULATOR receiver
G6N52_RS08440	COG2205	protein histidine kinase activity
G6N52_RS08445	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G6N52_RS08460	COG5416	Lipopolysaccharide assembly protein A domain
G6N52_RS08475	COG1174	glycine betaine transport
G6N52_RS08480	COG1174	glycine betaine transport
G6N52_RS08490	COG0287	Prephenate dehydrogenase
G6N52_RS08565	COG0343	queuine tRNA-ribosyltransferase activity
G6N52_RS08580	COG1126	abc transporter atp-binding protein
G6N52_RS08585	COG0765	amino acid transport
G6N52_RS08590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N52_RS08615	COG1793	dna ligase
G6N52_RS08630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N52_RS08660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N52_RS08690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N52_RS08705	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N52_RS08715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G6N52_RS08725	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G6N52_RS08770	COG0346	lactoylglutathione lyase activity
G6N52_RS08785	COG0243	molybdopterin cofactor binding
G6N52_RS08790	COG2860	membrane
G6N52_RS08795	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6N52_RS08825	COG1764	response to oxidative stress
G6N52_RS08835	COG3572	ergothioneine biosynthetic process
G6N52_RS08840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N52_RS08850	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G6N52_RS08855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N52_RS08875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6N52_RS08880	COG0477	Major facilitator Superfamily
G6N52_RS08885	COG1309	transcriptional regulator
G6N52_RS08905	COG0714	Associated with various cellular activities
G6N52_RS08935	COG1946	Acyl-CoA thioesterase
G6N52_RS08965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N52_RS08970	COG1408	metallophosphoesterase
G6N52_RS09005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N52_RS09060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N52_RS09065	COG4166	transmembrane transport
G6N52_RS09115	COG1111	helicase
G6N52_RS09115	COG1205	dead DEAH box helicase
G6N52_RS09120	COG1278	Cold shock
G6N52_RS09130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G6N52_RS09130	COG1754	DNA topoisomerase type I activity
G6N52_RS09140	COG0470	DNA polymerase III
G6N52_RS09150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N52_RS09200	COG1403	HNH endonuclease
G6N52_RS09210	COG2027	D-alanyl-D-alanine carboxypeptidase
G6N52_RS09250	COG2267	carboxylic ester hydrolase activity
G6N52_RS09255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N52_RS09260	COG0302	gtp cyclohydrolase
G6N52_RS09265	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G6N52_RS09270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G6N52_RS09295	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G6N52_RS09300	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G6N52_RS09305	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G6N52_RS09310	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G6N52_RS09325	COG1122	ATPase activity
G6N52_RS09340	COG0310	cobalt ion transport
G6N52_RS09345	COG4721	ABC-type cobalt transport system, permease component
G6N52_RS09350	COG4172	Belongs to the ABC transporter superfamily
G6N52_RS09375	COG0596	Alpha beta hydrolase
G6N52_RS09390	COG1194	a g-specific adenine glycosylase
G6N52_RS09405	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G6N52_RS09410	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G6N52_RS09420	COG1329	Transcriptional regulator
G6N52_RS09440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N52_RS09450	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G6N52_RS09460	COG1121	(ABC) transporter
G6N52_RS09465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6N52_RS09470	COG1609	Transcriptional regulator
G6N52_RS09480	COG1309	transcriptional regulator
G6N52_RS09485	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS09495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N52_RS09565	COG0436	Aminotransferase
G6N52_RS09570	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS09575	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS09580	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS09585	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS09590	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS09630	COG0183	Belongs to the thiolase family
G6N52_RS09665	COG1024	Enoyl-CoA hydratase
G6N52_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS09685	COG0406	alpha-ribazole phosphatase activity
G6N52_RS09700	COG0183	Belongs to the thiolase family
G6N52_RS09705	COG2124	cytochrome p450
G6N52_RS09710	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS09715	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS09720	COG2030	dehydratase
G6N52_RS09735	COG2030	dehydratase
G6N52_RS09740	COG1053	succinate dehydrogenase
G6N52_RS09745	COG3971	2-oxopent-4-enoate hydratase activity
G6N52_RS09750	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G6N52_RS09810	COG3321	synthase
G6N52_RS09810	COG0604	alcohol dehydrogenase
G6N52_RS09810	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS09815	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS09855	COG0514	ATP-dependent DNA helicase (RecQ)
G6N52_RS09890	COG4638	Rieske (2fe-2S)
G6N52_RS09915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS09925	COG2124	cytochrome p450
G6N52_RS09945	COG2070	2-Nitropropane dioxygenase
G6N52_RS09955	COG0028	Belongs to the TPP enzyme family
G6N52_RS09960	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS09965	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS09970	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS09980	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS10015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N52_RS10035	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G6N52_RS10040	COG1024	Enoyl-CoA hydratase
G6N52_RS10045	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS10050	COG2814	Major facilitator Superfamily
G6N52_RS10105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS10110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS10145	COG0745	RESPONSE REGULATOR receiver
G6N52_RS10150	COG5000	phosphorelay sensor kinase activity
G6N52_RS10150	COG5002	protein histidine kinase activity
G6N52_RS10165	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS10175	COG0251	oxidation-reduction process
G6N52_RS10185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N52_RS10225	COG2124	cytochrome p450
G6N52_RS10230	COG0300	oxidoreductase activity
G6N52_RS10245	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS10280	COG2072	flavoprotein involved in K transport
G6N52_RS10290	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS10295	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS10305	COG0183	Belongs to the thiolase family
G6N52_RS10310	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS10315	COG1802	Transcriptional regulator
G6N52_RS10320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS10330	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS10335	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS10340	COG1024	Enoyl-CoA hydratase
G6N52_RS10350	COG1024	Enoyl-CoA hydratase
G6N52_RS10355	COG1024	Enoyl-CoA hydratase
G6N52_RS10365	COG0300	oxidoreductase activity
G6N52_RS10370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N52_RS10380	COG1024	Enoyl-CoA hydratase
G6N52_RS10390	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS10405	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS10410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS10425	COG0183	Belongs to the thiolase family
G6N52_RS10460	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS10480	COG2072	flavoprotein involved in K transport
G6N52_RS10515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N52_RS10525	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS10535	COG0300	oxidoreductase activity
G6N52_RS10555	COG0531	amino acid
G6N52_RS10575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N52_RS10605	COG0386	Belongs to the glutathione peroxidase family
G6N52_RS10645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N52_RS10670	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N52_RS10700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G6N52_RS10730	COG4044	May play a role in the intracellular transport of hydrophobic ligands
G6N52_RS10740	COG2897	thiosulfate sulfurtransferase activity
G6N52_RS10755	COG0745	RESPONSE REGULATOR receiver
G6N52_RS10765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6N52_RS10775	COG0573	inorganic phosphate transmembrane transporter activity
G6N52_RS10780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G6N52_RS10795	COG1316	TRANSCRIPTIONal
G6N52_RS10815	COG0515	serine threonine protein kinase
G6N52_RS10820	COG5651	PPE family
G6N52_RS10820	COG3391	amine dehydrogenase activity
G6N52_RS10845	COG4974	Belongs to the 'phage' integrase family
G6N52_RS10870	COG2188	Transcriptional regulator
G6N52_RS10900	COG0464	growth
G6N52_RS10965	COG0183	Belongs to the thiolase family
G6N52_RS10970	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N52_RS10970	COG1024	Enoyl-CoA hydratase
G6N52_RS10980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS11020	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N52_RS11045	COG3304	Inner membrane component domain
G6N52_RS11050	COG1278	Cold shock
G6N52_RS11055	COG0435	Glutathione S-transferase
G6N52_RS11070	COG2814	Major facilitator Superfamily
G6N52_RS11110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G6N52_RS11130	COG0673	inositol 2-dehydrogenase activity
G6N52_RS11135	COG0673	inositol 2-dehydrogenase activity
G6N52_RS11150	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N52_RS11155	COG1116	anion transmembrane transporter activity
G6N52_RS11165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N52_RS11180	COG0596	Alpha beta hydrolase
G6N52_RS11210	COG0259	pyridoxamine-phosphate oxidase activity
G6N52_RS11215	COG1309	transcriptional regulator
G6N52_RS11230	COG0545	Peptidyl-prolyl cis-trans isomerase
G6N52_RS11250	COG1132	(ABC) transporter
G6N52_RS11255	COG1132	(ABC) transporter
G6N52_RS11270	COG1024	Enoyl-CoA hydratase
G6N52_RS11285	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N52_RS11320	COG0488	(ABC) transporter
G6N52_RS11345	COG1121	(ABC) transporter
G6N52_RS11350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6N52_RS11360	COG1733	regulation of RNA biosynthetic process
G6N52_RS11375	COG1403	HNH endonuclease
G6N52_RS11410	COG1755	Isoprenylcysteine carboxyl methyltransferase
G6N52_RS11425	COG0531	amino acid
G6N52_RS11435	COG1454	alcohol dehydrogenase
G6N52_RS11435	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS11450	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
G6N52_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS11495	COG1793	dna ligase
G6N52_RS11495	COG3285	dna ligase
G6N52_RS11500	COG0328	RNA-DNA hybrid ribonuclease activity
G6N52_RS11530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N52_RS11540	COG0166	Belongs to the GPI family
G6N52_RS11570	COG0045	succinate-CoA ligase (ADP-forming) activity
G6N52_RS11640	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N52_RS11660	COG1024	Enoyl-CoA hydratase
G6N52_RS11675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N52_RS11695	COG0745	RESPONSE REGULATOR receiver
G6N52_RS11705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N52_RS11710	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N52_RS11710	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N52_RS11740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6N52_RS11745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6N52_RS11775	COG1309	transcriptional regulator
G6N52_RS11780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N52_RS11780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N52_RS11785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6N52_RS11825	COG2235	arginine
G6N52_RS11850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6N52_RS11865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G6N52_RS11875	COG0084	hydrolase, TatD family'
G6N52_RS11880	COG3583	domain protein
G6N52_RS11885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6N52_RS11895	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G6N52_RS11900	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS11905	COG1660	Displays ATPase and GTPase activities
G6N52_RS11910	COG0193	aminoacyl-tRNA hydrolase activity
G6N52_RS11930	COG1393	Belongs to the ArsC family
G6N52_RS11950	COG1309	transcriptional regulator
G6N52_RS11965	COG3956	TIGRFAM MazG family protein
G6N52_RS11970	COG0659	secondary active sulfate transmembrane transporter activity
G6N52_RS11975	COG2837	iron assimilation
G6N52_RS11985	COG0672	)-iron permease
G6N52_RS11995	COG0148	phosphopyruvate hydratase activity
G6N52_RS12025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N52_RS12040	COG3328	transposase activity
G6N52_RS12100	COG1309	transcriptional regulator
G6N52_RS12145	COG4974	Belongs to the 'phage' integrase family
G6N52_RS12190	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
G6N52_RS12195	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS12225	COG1295	ribonuclease BN
G6N52_RS12245	COG0477	Major facilitator Superfamily
G6N52_RS12265	COG1846	Transcriptional regulator
G6N52_RS12270	COG4191	Histidine kinase
G6N52_RS12295	COG0765	amino acid transport
G6N52_RS12300	COG1126	abc transporter atp-binding protein
G6N52_RS12305	COG0456	acetyltransferase
G6N52_RS12310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G6N52_RS12320	COG5285	phytanoyl-CoA dioxygenase
G6N52_RS12325	COG2226	methyltransferase
G6N52_RS12345	COG1742	UPF0060 membrane protein
G6N52_RS12395	COG1024	Enoyl-CoA hydratase
G6N52_RS12405	COG0183	Belongs to the thiolase family
G6N52_RS12410	COG2755	lipolytic protein G-D-S-L family
G6N52_RS12415	COG0657	acetylesterase activity
G6N52_RS12425	COG5473	translation initiation factor activity
G6N52_RS12440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6N52_RS12450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N52_RS12460	COG1331	Highly conserved protein containing a thioredoxin domain
G6N52_RS12465	COG3631	Ketosteroid isomerase-related protein
G6N52_RS12475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G6N52_RS12500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6N52_RS12510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G6N52_RS12525	COG0477	Major facilitator Superfamily
G6N52_RS12565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N52_RS12575	COG3119	arylsulfatase activity
G6N52_RS12585	COG1722	exodeoxyribonuclease VII activity
G6N52_RS12590	COG1570	exodeoxyribonuclease VII activity
G6N52_RS12605	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N52_RS12615	COG0012	GTP binding
G6N52_RS12620	COG2824	Alkylphosphonate utilization operon protein PhnA
G6N52_RS12680	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS12695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6N52_RS12700	COG0596	Alpha beta hydrolase
G6N52_RS12705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS12735	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N52_RS12785	COG1024	Enoyl-CoA hydratase
G6N52_RS12795	COG0702	epimerase
G6N52_RS12810	COG1024	Enoyl-CoA hydratase
G6N52_RS12835	COG2409	Drug exporters of the RND superfamily
G6N52_RS12870	COG2508	Transcriptional regulator
G6N52_RS12875	COG2072	flavoprotein involved in K transport
G6N52_RS12895	COG3467	pyridoxamine 5'-phosphate
G6N52_RS12930	COG1051	belongs to the nudix hydrolase family
G6N52_RS12935	COG2154	pterin-4-alpha-carbinolamine dehydratase
G6N52_RS12955	COG1140	nitrate reductase beta subunit
G6N52_RS12975	COG1845	cytochrome c oxidase, subunit III
G6N52_RS13010	COG0747	negative chemotaxis
G6N52_RS13020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N52_RS13075	COG2353	YceI-like domain
G6N52_RS13100	COG0531	amino acid
G6N52_RS13110	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS13115	COG0506	proline dehydrogenase activity
G6N52_RS13130	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS13145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N52_RS13155	COG1611	Belongs to the LOG family
G6N52_RS13160	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS13165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G6N52_RS13170	COG0463	Glycosyl transferase, family 2
G6N52_RS13180	COG0519	Catalyzes the synthesis of GMP from XMP
G6N52_RS13190	COG0297	glycogen (starch) synthase activity
G6N52_RS13220	COG3559	Exporter of polyketide antibiotics
G6N52_RS13225	COG1131	(ABC) transporter
G6N52_RS13230	COG1309	transcriptional regulator
G6N52_RS13240	COG1595	DNA-templated transcription, initiation
G6N52_RS13245	COG5662	AntiSigma factor
G6N52_RS13250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N52_RS13255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N52_RS13275	COG2239	Acts as a magnesium transporter
G6N52_RS13330	COG0598	Magnesium transport protein CorA
G6N52_RS13355	COG0567	Dehydrogenase, E1 component
G6N52_RS13355	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N52_RS13365	COG2814	Major facilitator Superfamily
G6N52_RS13375	COG1116	anion transmembrane transporter activity
G6N52_RS13380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N52_RS13390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS13395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6N52_RS13430	COG0277	FAD linked oxidase domain protein
G6N52_RS13440	COG1733	regulation of RNA biosynthetic process
G6N52_RS13455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS13555	COG2837	iron assimilation
G6N52_RS13600	COG1218	3'(2'),5'-bisphosphate nucleotidase
G6N52_RS13635	COG2197	response regulator
G6N52_RS13650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS13665	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS13675	COG0559	Belongs to the binding-protein-dependent transport system permease family
G6N52_RS13700	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS13730	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N52_RS13735	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS13760	COG0270	DNA (cytosine-5-)-methyltransferase activity
G6N52_RS13775	COG0018	arginyl-trna synthetase
G6N52_RS13780	COG0019	diaminopimelate decarboxylase activity
G6N52_RS13785	COG0460	homoserine dehydrogenase
G6N52_RS13790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G6N52_RS13800	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G6N52_RS13805	COG1309	transcriptional regulator
G6N52_RS13810	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS13825	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N52_RS13845	COG0356	it plays a direct role in the translocation of protons across the membrane
G6N52_RS13850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N52_RS13855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6N52_RS13860	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6N52_RS13860	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N52_RS13865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G6N52_RS13870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G6N52_RS13875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G6N52_RS13895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6N52_RS13915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6N52_RS13925	COG2066	Belongs to the glutaminase family
G6N52_RS13925	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
G6N52_RS13935	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G6N52_RS13945	COG0346	lactoylglutathione lyase activity
G6N52_RS13950	COG0183	Belongs to the thiolase family
G6N52_RS13955	COG2409	Drug exporters of the RND superfamily
G6N52_RS13965	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6N52_RS13970	COG0366	Alpha amylase catalytic
G6N52_RS13975	COG0058	SHG alpha-glucan phosphorylase activity
G6N52_RS14000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G6N52_RS14005	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G6N52_RS14030	COG1234	tRNA 3'-trailer cleavage
G6N52_RS14035	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6N52_RS14040	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G6N52_RS14050	COG0477	Major facilitator Superfamily
G6N52_RS14080	COG2084	Dehydrogenase
G6N52_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS14095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N52_RS14095	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N52_RS14100	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N52_RS14105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS14110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS14125	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS14130	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS14160	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS14165	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G6N52_RS14180	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS14205	COG0778	Nitroreductase
G6N52_RS14205	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G6N52_RS14250	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS14255	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS14265	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6N52_RS14275	COG4638	Rieske (2fe-2S)
G6N52_RS14290	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS14295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS14300	COG0183	Belongs to the thiolase family
G6N52_RS14305	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS14310	COG1309	transcriptional regulator
G6N52_RS14325	COG2124	cytochrome p450
G6N52_RS14330	COG2084	Dehydrogenase
G6N52_RS14335	COG2084	Dehydrogenase
G6N52_RS14385	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS14400	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS14420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS14450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N52_RS14485	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS14495	COG1053	succinate dehydrogenase
G6N52_RS14510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N52_RS14520	COG1053	succinate dehydrogenase
G6N52_RS14550	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS14585	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS14590	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS14605	COG1024	Enoyl-CoA hydratase
G6N52_RS14610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS14625	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS14630	COG2124	cytochrome p450
G6N52_RS14645	COG1024	Enoyl-CoA hydratase
G6N52_RS14655	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS14735	COG0736	holo-[acyl-carrier-protein] synthase activity
G6N52_RS14740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N52_RS14765	COG0765	amino acid transport
G6N52_RS14770	COG0765	amino acid transport
G6N52_RS14775	COG1126	abc transporter atp-binding protein
G6N52_RS14820	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G6N52_RS14825	COG3485	protocatechuate 3,4-dioxygenase
G6N52_RS14835	COG1309	transcriptional regulator
G6N52_RS14840	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS14850	COG0028	Belongs to the TPP enzyme family
G6N52_RS14855	COG0069	glutamate synthase activity
G6N52_RS14865	COG1595	DNA-templated transcription, initiation
G6N52_RS14890	COG3328	transposase activity
G6N52_RS14900	COG1376	ErfK ybiS ycfS ynhG family protein
G6N52_RS14915	COG5651	PPE family
G6N52_RS14930	COG0433	COG0433 Predicted ATPase
G6N52_RS14935	COG4221	oxidoreductase activity
G6N52_RS14965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N52_RS14975	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS15000	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N52_RS15095	COG0629	single-stranded DNA binding
G6N52_RS15105	COG2902	Dehydrogenase
G6N52_RS15140	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G6N52_RS15150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6N52_RS15195	COG0544	peptidyl-prolyl cis-trans isomerase activity
G6N52_RS15210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G6N52_RS15215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G6N52_RS15240	COG1033	growth of symbiont in host cell
G6N52_RS15240	COG2409	Drug exporters of the RND superfamily
G6N52_RS15250	COG0673	inositol 2-dehydrogenase activity
G6N52_RS15255	COG3962	Belongs to the TPP enzyme family
G6N52_RS15260	COG3718	enzyme involved in inositol metabolism
G6N52_RS15270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N52_RS15275	COG2188	Transcriptional regulator
G6N52_RS15285	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6N52_RS15305	COG0673	inositol 2-dehydrogenase activity
G6N52_RS15315	COG0673	inositol 2-dehydrogenase activity
G6N52_RS15330	COG0674	pyruvate-flavodoxin oxidoreductase activity
G6N52_RS15330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G6N52_RS15335	COG1013	pyruvate-flavodoxin oxidoreductase activity
G6N52_RS15340	COG0746	molybdenum cofactor guanylyltransferase activity
G6N52_RS15345	COG1388	LysM domain
G6N52_RS15355	COG3268	Saccharopine dehydrogenase
G6N52_RS15365	COG0525	valine-tRNA ligase activity
G6N52_RS15370	COG0285	dihydrofolate synthase activity
G6N52_RS15385	COG0105	UTP biosynthetic process
G6N52_RS15390	COG1530	ribonuclease E activity
G6N52_RS15395	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G6N52_RS15405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6N52_RS15410	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G6N52_RS15435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N52_RS15440	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G6N52_RS15445	COG0542	response to heat
G6N52_RS15455	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G6N52_RS15460	COG0799	negative regulation of ribosome biogenesis
G6N52_RS15465	COG0406	alpha-ribazole phosphatase activity
G6N52_RS15470	COG2755	lipolytic protein G-D-S-L family
G6N52_RS15510	COG1305	Transglutaminase-like
G6N52_RS15535	COG0481	GTPase activity
G6N52_RS15540	COG1045	serine acetyltransferase
G6N52_RS15550	COG3119	arylsulfatase activity
G6N52_RS15555	COG4424	Sulfotransferase
G6N52_RS15565	COG3387	PFAM Glycoside hydrolase 15-related
G6N52_RS15585	COG4208	sulfate ABC transporter
G6N52_RS15590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G6N52_RS15620	COG1021	2,3-dihydroxybenzoate-AMP ligase
G6N52_RS15645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N52_RS15670	COG1420	regulation of RNA biosynthetic process
G6N52_RS15675	COG0484	heat shock protein binding
G6N52_RS15695	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G6N52_RS15725	COG1381	Involved in DNA repair and RecF pathway recombination
G6N52_RS15755	COG0423	glycine-tRNA ligase activity
G6N52_RS15770	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G6N52_RS15775	COG0358	DNA primase activity
G6N52_RS15845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N52_RS15850	COG3104	oligopeptide transport
G6N52_RS15860	COG0395	ABC-type sugar transport system, permease component
G6N52_RS15865	COG1175	transmembrane transport
G6N52_RS15875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N52_RS15880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6N52_RS15895	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G6N52_RS15945	COG0145	ligase activity
G6N52_RS15950	COG2814	Major facilitator Superfamily
G6N52_RS15970	COG2267	carboxylic ester hydrolase activity
G6N52_RS15980	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS16005	COG1024	Enoyl-CoA hydratase
G6N52_RS16010	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS16020	COG1137	ATPase activity
G6N52_RS16045	COG2188	Transcriptional regulator
G6N52_RS16065	COG2271	Major facilitator Superfamily
G6N52_RS16070	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G6N52_RS16080	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N52_RS16130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6N52_RS16135	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G6N52_RS16140	COG2080	2 iron, 2 sulfur cluster binding
G6N52_RS16160	COG0270	DNA (cytosine-5-)-methyltransferase activity
G6N52_RS16170	COG0210	DNA helicase
G6N52_RS16200	COG4584	PFAM Integrase catalytic
G6N52_RS16275	COG2813	Specifically methylates the guanine in position
G6N52_RS16345	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
G6N52_RS16350	COG2072	flavoprotein involved in K transport
G6N52_RS16390	COG0668	transmembrane transport
G6N52_RS16395	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G6N52_RS16450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N52_RS16470	COG2985	domain, Protein
G6N52_RS16470	COG0569	domain protein
G6N52_RS16480	COG2252	PERMEase
G6N52_RS16505	COG0640	Transcriptional regulator
G6N52_RS16515	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS16535	COG0747	negative chemotaxis
G6N52_RS16545	COG2720	vancomycin resistance protein
G6N52_RS16635	COG0583	DNA-binding transcription factor activity
G6N52_RS16640	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS16655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6N52_RS16660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N52_RS16665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G6N52_RS16675	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G6N52_RS16770	COG2813	Specifically methylates the guanine in position
G6N52_RS16775	COG1403	HNH endonuclease
G6N52_RS16795	COG1024	Enoyl-CoA hydratase
G6N52_RS16810	COG1595	DNA-templated transcription, initiation
G6N52_RS16815	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS16825	COG1595	DNA-templated transcription, initiation
G6N52_RS16850	COG0174	glutamine synthetase
G6N52_RS16855	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G6N52_RS16870	COG0450	alkyl hydroperoxide reductase
G6N52_RS16875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N52_RS16880	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS16885	COG2259	Doxx family
G6N52_RS16890	COG1490	D-aminoacyl-tRNA deacylase activity
G6N52_RS16895	COG0174	glutamine synthetase
G6N52_RS16920	COG0321	lipoyl(octanoyl) transferase activity
G6N52_RS16945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6N52_RS16950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6N52_RS16955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6N52_RS16960	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G6N52_RS16965	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G6N52_RS16985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N52_RS17030	COG2010	Cytochrome c
G6N52_RS17035	COG1845	cytochrome c oxidase, subunit III
G6N52_RS17040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G6N52_RS17085	COG0003	Pfam Anion-transporting ATPase
G6N52_RS17100	COG5650	phosphatidylinositol metabolic process
G6N52_RS17115	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G6N52_RS17170	COG0768	penicillin binding
G6N52_RS17190	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G6N52_RS17270	COG0243	molybdopterin cofactor binding
G6N52_RS17280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N52_RS17290	COG0167	dihydroorotate dehydrogenase activity
G6N52_RS17310	COG1968	undecaprenyl-diphosphatase activity
G6N52_RS17340	COG0215	cysteine-tRNA ligase activity
G6N52_RS17350	COG0646	methionine synthase
G6N52_RS17350	COG1410	methionine synthase
G6N52_RS17360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6N52_RS17365	COG0477	Major facilitator Superfamily
G6N52_RS17375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G6N52_RS17385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6N52_RS17400	COG0640	Transcriptional regulator
G6N52_RS17405	COG0798	PFAM Bile acid sodium symporter
G6N52_RS17465	COG4122	O-methyltransferase activity
G6N52_RS17475	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N52_RS17480	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N52_RS17485	COG1403	HNH endonuclease
G6N52_RS17490	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS17535	COG1872	DUF167
G6N52_RS17570	COG0539	negative regulation of cytoplasmic translation
G6N52_RS17580	COG0237	dephospho-CoA kinase activity
G6N52_RS17580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6N52_RS17640	COG1950	PFAM Membrane protein of
G6N52_RS17715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G6N52_RS17720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G6N52_RS17730	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS17745	COG0069	glutamate synthase activity
G6N52_RS17750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G6N52_RS17755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6N52_RS17755	COG0072	phenylalanine-tRNA ligase activity
G6N52_RS17770	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G6N52_RS17780	COG4804	nuclease activity
G6N52_RS17785	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G6N52_RS17800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G6N52_RS17805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6N52_RS17810	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6N52_RS17820	COG0137	argininosuccinate synthase activity
G6N52_RS17825	COG0165	Argininosuccinate lyase
G6N52_RS17835	COG0488	(ABC) transporter
G6N52_RS17845	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G6N52_RS17850	COG3639	organic phosphonate transmembrane transporter activity
G6N52_RS17855	COG2188	Transcriptional regulator
G6N52_RS17875	COG3627	carbon phosphorus lyase activity
G6N52_RS17880	COG4107	phosphonate C-P lyase system protein PhnK
G6N52_RS17885	COG1136	(ABC) transporter
G6N52_RS17905	COG2835	tetraacyldisaccharide 4'-kinase activity
G6N52_RS17940	COG0647	UMP catabolic process
G6N52_RS17975	COG0504	CTP synthase activity
G6N52_RS18010	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6N52_RS18025	COG1160	GTP binding
G6N52_RS18035	COG0730	response to heat
G6N52_RS18045	COG0582	viral genome integration into host DNA
G6N52_RS18075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS18085	COG0166	Belongs to the GPI family
G6N52_RS18090	COG0477	Major facilitator Superfamily
G6N52_RS18115	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS18125	COG0183	Belongs to the thiolase family
G6N52_RS18130	COG1024	Enoyl-CoA hydratase
G6N52_RS18130	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N52_RS18135	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G6N52_RS18140	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS18155	COG0633	Ferredoxin
G6N52_RS18170	COG0667	Aldo Keto reductase
G6N52_RS18185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS18215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N52_RS18270	COG0460	homoserine dehydrogenase
G6N52_RS18290	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS18340	COG1309	transcriptional regulator
G6N52_RS18350	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS18355	COG0183	Belongs to the thiolase family
G6N52_RS18370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6N52_RS18460	COG1716	ATPase activity
G6N52_RS18500	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS18530	COG2076	Multidrug Resistance protein
G6N52_RS18540	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N52_RS18550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N52_RS18565	COG1053	succinate dehydrogenase
G6N52_RS18605	COG0509	glycine decarboxylation via glycine cleavage system
G6N52_RS18610	COG1716	ATPase activity
G6N52_RS18630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6N52_RS18630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6N52_RS18650	COG1253	flavin adenine dinucleotide binding
G6N52_RS18655	COG1253	flavin adenine dinucleotide binding
G6N52_RS18660	COG1840	ABC-type Fe3 transport system, periplasmic component
G6N52_RS18680	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G6N52_RS18705	COG0831	urea catabolic process
G6N52_RS18715	COG0804	urea catabolic process
G6N52_RS18720	COG0830	nickel cation binding
G6N52_RS18725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G6N52_RS18730	COG0829	nickel cation binding
G6N52_RS18735	COG1252	NADH dehydrogenase
G6N52_RS18740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS18770	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G6N52_RS18775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS18785	COG0183	Belongs to the thiolase family
G6N52_RS18810	COG0668	transmembrane transport
G6N52_RS18815	COG5002	protein histidine kinase activity
G6N52_RS18845	COG1289	transmembrane transporter activity
G6N52_RS18855	COG1024	Enoyl-CoA hydratase
G6N52_RS18865	COG2193	ferroxidase activity
G6N52_RS18890	COG1946	Acyl-CoA thioesterase
G6N52_RS18895	COG0438	transferase activity, transferring glycosyl groups
G6N52_RS18970	COG2070	2-Nitropropane dioxygenase
G6N52_RS18975	COG0596	Alpha beta hydrolase
G6N52_RS18985	COG1058	Belongs to the CinA family
G6N52_RS18985	COG1546	Belongs to the CinA family
G6N52_RS19000	COG2207	Transcriptional regulator
G6N52_RS19000	COG0662	Cupin 2, conserved barrel domain protein
G6N52_RS19015	COG3022	response to hydroperoxide
G6N52_RS19035	COG0697	spore germination
G6N52_RS19040	COG2755	lipolytic protein G-D-S-L family
G6N52_RS19040	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N52_RS19045	COG2755	lipolytic protein G-D-S-L family
G6N52_RS19050	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G6N52_RS19060	COG4948	Mandelate Racemase Muconate Lactonizing
G6N52_RS19080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G6N52_RS19090	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS19130	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G6N52_RS19135	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G6N52_RS19140	COG3639	organic phosphonate transmembrane transporter activity
G6N52_RS19150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6N52_RS19155	COG1063	alcohol dehydrogenase
G6N52_RS19185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N52_RS19205	COG0545	Peptidyl-prolyl cis-trans isomerase
G6N52_RS19230	COG2267	carboxylic ester hydrolase activity
G6N52_RS19260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N52_RS19340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N52_RS19375	COG1063	alcohol dehydrogenase
G6N52_RS19385	COG1309	transcriptional regulator
G6N52_RS19395	COG3328	transposase activity
G6N52_RS19405	COG4691	Plasmid stability protein
G6N52_RS19410	COG1487	ribonuclease activity
G6N52_RS19420	COG0604	alcohol dehydrogenase
G6N52_RS19435	COG2337	Toxic component of a toxin-antitoxin (TA) module
G6N52_RS19445	COG3328	transposase activity
G6N52_RS19480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS19485	COG3243	poly(R)-hydroxyalkanoic acid synthase
G6N52_RS19495	COG0803	Belongs to the bacterial solute-binding protein 9 family
G6N52_RS19500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6N52_RS19505	COG1121	(ABC) transporter
G6N52_RS19520	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G6N52_RS19525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6N52_RS19530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G6N52_RS19570	COG0477	Major facilitator Superfamily
G6N52_RS19585	COG0675	Transposase, IS605 OrfB family
G6N52_RS19600	COG2204	response regulator
G6N52_RS19605	COG4251	negative regulation of phosphorylation
G6N52_RS19610	COG0784	Response regulator, receiver
G6N52_RS19615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS19625	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS19640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N52_RS19660	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS19675	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6N52_RS19680	COG1177	transmembrane transport
G6N52_RS19690	COG1335	isochorismatase
G6N52_RS19695	COG0438	transferase activity, transferring glycosyl groups
G6N52_RS19700	COG2226	methyltransferase
G6N52_RS19735	COG3265	gluconokinase activity
G6N52_RS19750	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N52_RS19770	COG0463	Glycosyl transferase, family 2
G6N52_RS19780	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6N52_RS19830	COG0300	oxidoreductase activity
G6N52_RS19870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N52_RS19875	COG2378	regulation of single-species biofilm formation
G6N52_RS19885	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N52_RS19950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N52_RS19960	COG1271	oxidase subunit
G6N52_RS19965	COG1294	oxidase, subunit
G6N52_RS19970	COG4988	ABC transporter
G6N52_RS19975	COG1132	(ABC) transporter
G6N52_RS19985	COG1946	Acyl-CoA thioesterase
G6N52_RS20010	COG0159	tryptophan synthase activity
G6N52_RS20020	COG0134	indole-3-glycerol-phosphate synthase activity
G6N52_RS20040	COG1119	ATPase activity
G6N52_RS20045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G6N52_RS20050	COG0107	imidazoleglycerol-phosphate synthase activity
G6N52_RS20055	COG0483	inositol monophosphate 1-phosphatase activity
G6N52_RS20060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G6N52_RS20065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G6N52_RS20070	COG0131	Imidazoleglycerol-phosphate dehydratase
G6N52_RS20075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N52_RS20090	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G6N52_RS20095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G6N52_RS20140	COG0156	8-amino-7-oxononanoate synthase activity
G6N52_RS20145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6N52_RS20195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N52_RS20210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G6N52_RS20215	COG0252	asparaginase activity
G6N52_RS20230	COG1403	HNH endonuclease
G6N52_RS20235	COG2501	S4 domain
G6N52_RS20240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G6N52_RS20320	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6N52_RS20330	COG2304	oxidoreductase activity
G6N52_RS20340	COG0714	Associated with various cellular activities
G6N52_RS20350	COG3883	PFAM NLP P60 protein
G6N52_RS20350	COG0791	NLP P60 protein
G6N52_RS20360	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6N52_RS20365	COG1309	transcriptional regulator
G6N52_RS20375	COG0488	(ABC) transporter
G6N52_RS20385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N52_RS20395	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS20420	COG2151	metal-sulfur cluster biosynthetic enzyme
G6N52_RS20435	COG0396	ATPase activity
G6N52_RS20495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6N52_RS20515	COG1556	Lactate utilization protein
G6N52_RS20520	COG1139	Iron-sulfur cluster binding protein
G6N52_RS20525	COG0247	lactate metabolic process
G6N52_RS20550	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G6N52_RS20565	COG0149	triose-phosphate isomerase activity
G6N52_RS20570	COG0126	phosphoglycerate kinase activity
G6N52_RS20575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G6N52_RS20590	COG1481	regulation of sporulation
G6N52_RS20605	COG0322	excinuclease ABC activity
G6N52_RS20620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N52_RS20620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N52_RS20635	COG0477	Major facilitator Superfamily
G6N52_RS20640	COG0693	protein deglycase activity
G6N52_RS20665	COG0463	Glycosyl transferase, family 2
G6N52_RS20765	COG2072	flavoprotein involved in K transport
G6N52_RS20780	COG1758	RNA polymerase activity
G6N52_RS20795	COG0284	orotidine-5'-phosphate decarboxylase activity
G6N52_RS20805	COG0505	Belongs to the CarA family
G6N52_RS20825	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G6N52_RS20840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS20850	COG0583	DNA-binding transcription factor activity
G6N52_RS20865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G6N52_RS20870	COG0006	proline dipeptidase activity
G6N52_RS20880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G6N52_RS20885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G6N52_RS20900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6N52_RS20910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G6N52_RS20915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6N52_RS20920	COG0432	Pfam Uncharacterised protein family UPF0047
G6N52_RS20960	COG0183	Belongs to the thiolase family
G6N52_RS20965	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS20970	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS20975	COG1024	Enoyl-CoA hydratase
G6N52_RS20980	COG1024	Enoyl-CoA hydratase
G6N52_RS20995	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS21005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N52_RS21035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS21040	COG0183	Belongs to the thiolase family
G6N52_RS21045	COG1024	Enoyl-CoA hydratase
G6N52_RS21055	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS21075	COG1309	transcriptional regulator
G6N52_RS21080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G6N52_RS21085	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N52_RS21115	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS21120	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS21135	COG3973	AAA domain
G6N52_RS21180	COG0124	histidyl-tRNA synthetase
G6N52_RS21200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6N52_RS21205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G6N52_RS21210	COG0747	negative chemotaxis
G6N52_RS21215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N52_RS21240	COG1403	HNH endonuclease
G6N52_RS21260	COG0217	transcriptional regulatory protein
G6N52_RS21265	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS21270	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS21280	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G6N52_RS21285	COG1946	Acyl-CoA thioesterase
G6N52_RS21300	COG0438	transferase activity, transferring glycosyl groups
G6N52_RS21305	COG1560	Kdo2-lipid A biosynthetic process
G6N52_RS21310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G6N52_RS21350	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS21470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS21505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N52_RS21505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N52_RS21520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N52_RS21535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G6N52_RS21545	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G6N52_RS21555	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G6N52_RS21565	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G6N52_RS21570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6N52_RS21575	COG0531	amino acid
G6N52_RS21580	COG0569	domain protein
G6N52_RS21610	COG0756	dUTP diphosphatase activity
G6N52_RS21630	COG0483	inositol monophosphate 1-phosphatase activity
G6N52_RS21700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G6N52_RS21710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6N52_RS21720	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS21725	COG1309	transcriptional regulator
G6N52_RS21730	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS21745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6N52_RS21750	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G6N52_RS21755	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G6N52_RS21765	COG0697	spore germination
G6N52_RS21770	COG1196	nuclear chromosome segregation
G6N52_RS21780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6N52_RS21785	COG1126	abc transporter atp-binding protein
G6N52_RS21790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N52_RS21795	COG0765	amino acid transport
G6N52_RS21800	COG0765	amino acid transport
G6N52_RS21810	COG1846	Transcriptional regulator
G6N52_RS21815	COG2137	regulation of response to DNA damage stimulus
G6N52_RS21820	COG1372	Participates in initiation and elongation during chromosome replication
G6N52_RS21820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G6N52_RS21840	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
G6N52_RS21860	COG1396	sequence-specific DNA binding
G6N52_RS21870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G6N52_RS21880	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G6N52_RS21900	COG5002	protein histidine kinase activity
G6N52_RS21910	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G6N52_RS21915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N52_RS21920	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
G6N52_RS21925	COG3214	Protein conserved in bacteria
G6N52_RS21935	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G6N52_RS21950	COG2807	transmembrane transport
G6N52_RS21970	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS21980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N52_RS21985	COG1024	Enoyl-CoA hydratase
G6N52_RS21985	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N52_RS21995	COG0492	ferredoxin-NADP+ reductase activity
G6N52_RS22000	COG2508	Transcriptional regulator
G6N52_RS22005	COG0318	PFAM AMP-dependent synthetase and ligase
G6N52_RS22010	COG0686	Belongs to the AlaDH PNT family
G6N52_RS22015	COG3012	SEC-C Motif Domain Protein
G6N52_RS22035	COG1185	polyribonucleotide nucleotidyltransferase activity
G6N52_RS22045	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G6N52_RS22100	COG1024	Enoyl-CoA hydratase
G6N52_RS22105	COG1929	Belongs to the glycerate kinase type-1 family
G6N52_RS22120	COG0673	inositol 2-dehydrogenase activity
G6N52_RS22125	COG1609	Transcriptional regulator
G6N52_RS22130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N52_RS22135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6N52_RS22140	COG1116	anion transmembrane transporter activity
G6N52_RS22150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G6N52_RS22175	COG0779	Required for maturation of 30S ribosomal subunits
G6N52_RS22190	COG0442	prolyl-tRNA aminoacylation
G6N52_RS22200	COG1648	precorrin-2 dehydrogenase activity
G6N52_RS22200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N52_RS22235	COG0640	Transcriptional regulator
G6N52_RS22255	COG0367	asparagine synthase
G6N52_RS22305	COG0750	zinc metalloprotease
G6N52_RS22310	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G6N52_RS22325	COG0415	Belongs to the DNA photolyase family
G6N52_RS22335	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G6N52_RS22350	COG0528	UMP kinase activity
G6N52_RS22360	COG0601	transmembrane transport
G6N52_RS22365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6N52_RS22370	COG0444	Belongs to the ABC transporter superfamily
G6N52_RS22375	COG3842	ATPase activity
G6N52_RS22380	COG0154	amidase activity
G6N52_RS22385	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G6N52_RS22390	COG0052	Belongs to the universal ribosomal protein uS2 family
G6N52_RS22415	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G6N52_RS22425	COG3800	Transcriptional regulator
G6N52_RS22425	COG1396	sequence-specific DNA binding
G6N52_RS22460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G6N52_RS22505	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G6N52_RS22510	COG1686	Belongs to the peptidase S11 family
G6N52_RS22515	COG1686	Belongs to the peptidase S11 family
G6N52_RS22530	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G6N52_RS22555	COG1196	nuclear chromosome segregation
G6N52_RS22560	COG1254	Belongs to the acylphosphatase family
G6N52_RS22575	COG0571	ribonuclease III activity
G6N52_RS22585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS22595	COG3599	regulation of cell shape
G6N52_RS22600	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G6N52_RS22605	COG0742	ribosomal rna small subunit methyltransferase
G6N52_RS22630	COG0656	L-ascorbic acid biosynthetic process
G6N52_RS22650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G6N52_RS22655	COG1461	Dihydroxyacetone kinase
G6N52_RS22670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G6N52_RS22690	COG0626	cystathionine gamma-synthase activity
G6N52_RS22700	COG1920	GTP binding
G6N52_RS22705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G6N52_RS22725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6N52_RS22755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N52_RS22760	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N52_RS22780	COG2271	Major facilitator Superfamily
G6N52_RS22785	COG0473	3-isopropylmalate dehydrogenase activity
G6N52_RS22805	COG0440	acetolactate synthase activity
G6N52_RS22825	COG2133	pyrroloquinoline quinone binding
G6N52_RS22830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6N52_RS22835	COG1414	Transcriptional regulator
G6N52_RS22855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6N52_RS22870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G6N52_RS22910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6N52_RS22910	COG2213	PTS system mannitol-specific
G6N52_RS22915	COG1063	alcohol dehydrogenase
G6N52_RS22920	COG0482	sulfurtransferase activity
G6N52_RS22950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N52_RS22965	COG0110	maltose O-acetyltransferase activity
G6N52_RS22970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N52_RS23005	COG1119	ATPase activity
G6N52_RS23010	COG2364	Membrane
G6N52_RS23015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N52_RS23040	COG1064	alcohol dehydrogenase
G6N52_RS23055	COG1309	transcriptional regulator
G6N52_RS23170	COG1937	Protein conserved in bacteria
G6N52_RS23185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N52_RS23200	COG0659	secondary active sulfate transmembrane transporter activity
G6N52_RS23215	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G6N52_RS23240	COG0713	ATP synthesis coupled electron transport
G6N52_RS23250	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N52_RS23255	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G6N52_RS23260	COG1034	ATP synthesis coupled electron transport
G6N52_RS23285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N52_RS23305	COG0409	Hydrogenase expression formation protein
G6N52_RS23315	COG0309	Hydrogenase expression formation protein (HypE)
G6N52_RS23320	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G6N52_RS23370	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
G6N52_RS23390	COG0464	growth
G6N52_RS23395	COG4451	ribulose bisphosphate carboxylase, small
G6N52_RS23400	COG1850	ribulose-bisphosphate carboxylase activity
G6N52_RS23405	COG3588	fructose-bisphosphate aldolase
G6N52_RS23415	COG2197	response regulator
G6N52_RS23425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G6N52_RS23430	COG0572	uridine kinase
G6N52_RS23435	COG0375	protein maturation
G6N52_RS23460	COG0316	Belongs to the HesB IscA family
G6N52_RS23460	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G6N52_RS23505	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS23510	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS23520	COG2186	Transcriptional regulator
G6N52_RS23525	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS23540	COG1966	Carbon starvation protein
G6N52_RS23555	COG0513	Belongs to the DEAD box helicase family
G6N52_RS23560	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS23565	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS23595	COG4221	oxidoreductase activity
G6N52_RS23615	COG1525	nuclease
G6N52_RS23665	COG0477	Major facilitator Superfamily
G6N52_RS23675	COG2814	Major facilitator Superfamily
G6N52_RS23680	COG1295	ribonuclease BN
G6N52_RS23685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G6N52_RS23690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G6N52_RS23775	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G6N52_RS23785	COG2884	Cell division ATP-binding protein ftsE
G6N52_RS23795	COG0668	transmembrane transport
G6N52_RS23800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G6N52_RS23815	COG0483	inositol monophosphate 1-phosphatase activity
G6N52_RS23825	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS23845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS23850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N52_RS23855	COG1309	transcriptional regulator
G6N52_RS23860	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS23890	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N52_RS23895	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N52_RS23915	COG1034	ATP synthesis coupled electron transport
G6N52_RS23925	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N52_RS23935	COG0713	ATP synthesis coupled electron transport
G6N52_RS23980	COG1024	Enoyl-CoA hydratase
G6N52_RS23990	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS24025	COG2267	carboxylic ester hydrolase activity
G6N52_RS24090	COG0656	L-ascorbic acid biosynthetic process
G6N52_RS24095	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G6N52_RS24105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N52_RS24115	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS24130	COG2072	flavoprotein involved in K transport
G6N52_RS24140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS24150	COG1902	pentaerythritol trinitrate reductase activity
G6N52_RS24150	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N52_RS24155	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS24200	COG1522	sequence-specific DNA binding
G6N52_RS24205	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G6N52_RS24225	COG0604	alcohol dehydrogenase
G6N52_RS24230	COG1053	succinate dehydrogenase
G6N52_RS24310	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N52_RS24320	COG2124	cytochrome p450
G6N52_RS24335	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS24350	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N52_RS24355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N52_RS24370	COG3848	Pyruvate phosphate dikinase
G6N52_RS24370	COG0574	Belongs to the PEP-utilizing enzyme family
G6N52_RS24375	COG0574	Belongs to the PEP-utilizing enzyme family
G6N52_RS24375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N52_RS24410	COG1063	alcohol dehydrogenase
G6N52_RS24435	COG1615	UPF0182 protein
G6N52_RS24440	COG3480	Lon protease (S16) C-terminal proteolytic domain
G6N52_RS24455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N52_RS24485	COG0475	glutathione-regulated potassium exporter activity
G6N52_RS24485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N52_RS24505	COG0596	Alpha beta hydrolase
G6N52_RS24550	COG0513	Belongs to the DEAD box helicase family
G6N52_RS24565	COG0406	alpha-ribazole phosphatase activity
G6N52_RS24585	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G6N52_RS24595	COG3485	protocatechuate 3,4-dioxygenase
G6N52_RS24600	COG4948	Mandelate Racemase Muconate Lactonizing
G6N52_RS24605	COG0583	DNA-binding transcription factor activity
G6N52_RS24610	COG4638	Rieske (2fe-2S)
G6N52_RS24645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N52_RS24650	COG0183	Belongs to the thiolase family
G6N52_RS24655	COG0583	DNA-binding transcription factor activity
G6N52_RS24660	COG1597	lipid kinase activity
G6N52_RS24675	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N52_RS24685	COG5662	AntiSigma factor
G6N52_RS24690	COG1595	DNA-templated transcription, initiation
G6N52_RS24695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G6N52_RS24700	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS24710	COG2135	peptidase activity
G6N52_RS24715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6N52_RS24720	COG1162	GTPase activity
G6N52_RS24745	COG2326	polyphosphate kinase activity
G6N52_RS24750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G6N52_RS24765	COG0653	protein targeting
G6N52_RS24770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G6N52_RS24790	COG0745	RESPONSE REGULATOR receiver
G6N52_RS24840	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N52_RS24845	COG0531	amino acid
G6N52_RS24850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N52_RS24855	COG1482	cell wall glycoprotein biosynthetic process
G6N52_RS24865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N52_RS24900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6N52_RS24910	COG1091	dTDP-4-dehydrorhamnose reductase activity
G6N52_RS24915	COG1316	TRANSCRIPTIONal
G6N52_RS24955	COG0424	maF-like protein
G6N52_RS24975	COG4770	biotin carboxylase activity
G6N52_RS24985	COG0039	L-malate dehydrogenase activity
G6N52_RS25035	COG1012	belongs to the aldehyde dehydrogenase family
G6N52_RS25070	COG1201	RNA secondary structure unwinding
G6N52_RS25085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS25100	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS25105	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS25110	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS25135	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS25140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N52_RS25175	COG0583	DNA-binding transcription factor activity
G6N52_RS25195	COG2084	Dehydrogenase
G6N52_RS25225	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N52_RS25260	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS25280	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS25285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N52_RS25325	COG0243	molybdopterin cofactor binding
G6N52_RS25335	COG1024	Enoyl-CoA hydratase
G6N52_RS25370	COG1309	transcriptional regulator
G6N52_RS25375	COG0564	pseudouridine synthase activity
G6N52_RS25395	COG1473	amidohydrolase
G6N52_RS25395	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N52_RS25410	COG3180	Ammonia monooxygenase
G6N52_RS25420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N52_RS25455	COG2009	succinate dehydrogenase
G6N52_RS25470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G6N52_RS25490	COG1595	DNA-templated transcription, initiation
G6N52_RS25515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6N52_RS25530	COG1686	Belongs to the peptidase S11 family
G6N52_RS25545	COG1295	ribonuclease BN
G6N52_RS25565	COG2873	o-acetylhomoserine
G6N52_RS25570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N52_RS25595	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N52_RS25595	COG1902	pentaerythritol trinitrate reductase activity
G6N52_RS25600	COG1716	ATPase activity
G6N52_RS25600	COG1131	(ABC) transporter
G6N52_RS25600	COG0842	Transport permease protein
G6N52_RS25610	COG1357	PFAM Pentapeptide repeats (8 copies)
G6N52_RS25625	COG2018	Roadblock/LC7 domain
G6N52_RS25635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6N52_RS25685	COG1946	Acyl-CoA thioesterase
G6N52_RS25690	COG0406	alpha-ribazole phosphatase activity
G6N52_RS25715	COG0519	Catalyzes the synthesis of GMP from XMP
G6N52_RS25715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6N52_RS25725	COG0516	GMP reductase activity
G6N52_RS25765	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS25770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G6N52_RS25795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G6N52_RS25815	COG0456	acetyltransferase
G6N52_RS25830	COG2267	carboxylic ester hydrolase activity
G6N52_RS25840	COG0076	glutamate decarboxylase activity
G6N52_RS25855	COG2267	carboxylic ester hydrolase activity
G6N52_RS25860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6N52_RS25870	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N52_RS25880	COG0183	Belongs to the thiolase family
G6N52_RS25895	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS25900	COG1960	acyl-CoA dehydrogenase activity
G6N52_RS25910	COG0022	dehydrogenase e1 component
G6N52_RS25915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N52_RS25925	COG2217	Heavy metal translocating P-type atpase
G6N52_RS25935	COG2132	Multicopper oxidase
G6N52_RS25945	COG0745	RESPONSE REGULATOR receiver
G6N52_RS25950	COG2205	protein histidine kinase activity
G6N52_RS25970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N52_RS25980	COG2755	lipolytic protein G-D-S-L family
G6N52_RS25980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N52_RS25990	COG1733	regulation of RNA biosynthetic process
G6N52_RS26005	COG0714	Associated with various cellular activities
G6N52_RS26030	COG4638	Rieske (2fe-2S)
G6N52_RS26035	COG1028	Short-chain dehydrogenase reductase Sdr
G6N52_RS26040	COG2124	cytochrome p450
G6N52_RS26045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component