locus-tag	class	description
G6N10_RS00025	COG3237	CsbD-like
G6N10_RS00090	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N10_RS00110	COG0356	it plays a direct role in the translocation of protons across the membrane
G6N10_RS00115	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N10_RS00125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N10_RS00125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6N10_RS00130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G6N10_RS00135	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G6N10_RS00145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G6N10_RS00160	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6N10_RS00180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6N10_RS00195	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G6N10_RS00210	COG0183	Belongs to the thiolase family
G6N10_RS00220	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6N10_RS00240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G6N10_RS00255	COG3191	aminopeptidase activity
G6N10_RS00265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G6N10_RS00275	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6N10_RS00310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N10_RS00320	COG1403	HNH endonuclease
G6N10_RS00335	COG0300	oxidoreductase activity
G6N10_RS00345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N10_RS00360	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS00365	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS00375	COG1012	belongs to the aldehyde dehydrogenase family
G6N10_RS00390	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS00395	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS00400	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS00420	COG4638	Rieske (2fe-2S)
G6N10_RS00435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N10_RS00440	COG0183	Belongs to the thiolase family
G6N10_RS00445	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS00475	COG2084	Dehydrogenase
G6N10_RS00495	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6N10_RS00525	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS00530	COG0022	dehydrogenase e1 component
G6N10_RS00535	COG1012	belongs to the aldehyde dehydrogenase family
G6N10_RS00550	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS00570	COG2124	cytochrome p450
G6N10_RS00575	COG1309	transcriptional regulator
G6N10_RS00585	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS00590	COG2124	cytochrome p450
G6N10_RS00600	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS00610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N10_RS00615	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N10_RS00620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N10_RS00645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N10_RS00680	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS00705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N10_RS00710	COG3384	dioxygenase
G6N10_RS00715	COG1053	succinate dehydrogenase
G6N10_RS00725	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS00750	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS00785	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS00800	COG1024	Enoyl-CoA hydratase
G6N10_RS00805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N10_RS00810	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS00815	COG2124	cytochrome p450
G6N10_RS00820	COG2124	cytochrome p450
G6N10_RS00835	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS00855	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G6N10_RS00865	COG2271	Major facilitator Superfamily
G6N10_RS00870	COG3757	hydrolase, family 25
G6N10_RS00880	COG0736	holo-[acyl-carrier-protein] synthase activity
G6N10_RS00945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N10_RS00950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N10_RS00955	COG1309	transcriptional regulator
G6N10_RS00970	COG1464	Belongs to the NlpA lipoprotein family
G6N10_RS00975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G6N10_RS00980	COG2011	ABC-type metal ion transport system permease component
G6N10_RS00995	COG0440	acetolactate synthase activity
G6N10_RS01015	COG0473	3-isopropylmalate dehydrogenase activity
G6N10_RS01025	COG0028	Belongs to the TPP enzyme family
G6N10_RS01040	COG2271	Major facilitator Superfamily
G6N10_RS01050	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N10_RS01055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N10_RS01080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6N10_RS01100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G6N10_RS01105	COG1920	GTP binding
G6N10_RS01115	COG0626	cystathionine gamma-synthase activity
G6N10_RS01140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G6N10_RS01150	COG1461	Dihydroxyacetone kinase
G6N10_RS01155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G6N10_RS01165	COG0656	L-ascorbic acid biosynthetic process
G6N10_RS01190	COG0742	ribosomal rna small subunit methyltransferase
G6N10_RS01200	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G6N10_RS01205	COG3599	regulation of cell shape
G6N10_RS01215	COG0571	ribonuclease III activity
G6N10_RS01230	COG1254	Belongs to the acylphosphatase family
G6N10_RS01235	COG1196	nuclear chromosome segregation
G6N10_RS01250	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G6N10_RS01265	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G6N10_RS01290	COG1686	Belongs to the peptidase S11 family
G6N10_RS01325	COG0335	large ribosomal subunit rRNA binding
G6N10_RS01335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G6N10_RS01350	COG0792	nuclease activity
G6N10_RS01390	COG2267	carboxylic ester hydrolase activity
G6N10_RS01400	COG0052	Belongs to the universal ribosomal protein uS2 family
G6N10_RS01405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G6N10_RS01410	COG0154	amidase activity
G6N10_RS01415	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G6N10_RS01425	COG0754	glutathionylspermidine amidase activity
G6N10_RS01435	COG0528	UMP kinase activity
G6N10_RS01440	COG0233	cytoplasmic translational termination
G6N10_RS01445	COG0575	Belongs to the CDS family
G6N10_RS01450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G6N10_RS01465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G6N10_RS01470	COG0750	zinc metalloprotease
G6N10_RS01510	COG1492	cobalamin metabolic process
G6N10_RS01525	COG0579	oxidoreductase
G6N10_RS01550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N10_RS01550	COG1648	precorrin-2 dehydrogenase activity
G6N10_RS01575	COG2072	flavoprotein involved in K transport
G6N10_RS01595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N10_RS01610	COG3800	Transcriptional regulator
G6N10_RS01610	COG1396	sequence-specific DNA binding
G6N10_RS01620	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G6N10_RS01635	COG1733	regulation of RNA biosynthetic process
G6N10_RS01665	COG0779	Required for maturation of 30S ribosomal subunits
G6N10_RS01700	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G6N10_RS01715	COG1024	Enoyl-CoA hydratase
G6N10_RS01780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N10_RS01800	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G6N10_RS01825	COG3012	SEC-C Motif Domain Protein
G6N10_RS01870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N10_RS01885	COG0659	secondary active sulfate transmembrane transporter activity
G6N10_RS01895	COG2807	transmembrane transport
G6N10_RS01910	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G6N10_RS01920	COG3214	Protein conserved in bacteria
G6N10_RS01930	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G6N10_RS01945	COG2442	InterPro IPR007367
G6N10_RS01950	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G6N10_RS01960	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
G6N10_RS01965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N10_RS01970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G6N10_RS01995	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G6N10_RS02005	COG1396	sequence-specific DNA binding
G6N10_RS02020	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
G6N10_RS02040	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G6N10_RS02040	COG1372	Participates in initiation and elongation during chromosome replication
G6N10_RS02045	COG2137	regulation of response to DNA damage stimulus
G6N10_RS02050	COG0765	amino acid transport
G6N10_RS02055	COG0765	amino acid transport
G6N10_RS02060	COG1126	abc transporter atp-binding protein
G6N10_RS02065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6N10_RS02080	COG1196	nuclear chromosome segregation
G6N10_RS02095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G6N10_RS02100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G6N10_RS02105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6N10_RS02110	COG5651	PPE family
G6N10_RS02110	COG3391	amine dehydrogenase activity
G6N10_RS02125	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS02130	COG1309	transcriptional regulator
G6N10_RS02135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G6N10_RS02150	COG1140	nitrate reductase beta subunit
G6N10_RS02185	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N10_RS02200	COG0314	molybdopterin synthase activity
G6N10_RS02205	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N10_RS02205	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N10_RS02210	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS02215	COG5479	isomerase activity
G6N10_RS02215	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N10_RS02220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6N10_RS02235	COG1388	LysM domain
G6N10_RS02320	COG0756	dUTP diphosphatase activity
G6N10_RS02350	COG0569	domain protein
G6N10_RS02355	COG0531	amino acid
G6N10_RS02360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6N10_RS02365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G6N10_RS02370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G6N10_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS02405	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G6N10_RS02425	COG1403	HNH endonuclease
G6N10_RS02430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N10_RS02445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N10_RS02445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N10_RS02505	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS02530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G6N10_RS02535	COG1560	Kdo2-lipid A biosynthetic process
G6N10_RS02540	COG0438	transferase activity, transferring glycosyl groups
G6N10_RS02550	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
G6N10_RS02570	COG0732	type I restriction modification DNA specificity domain
G6N10_RS02590	COG2161	toxin-antitoxin pair type II binding
G6N10_RS02595	COG4115	mRNA cleavage
G6N10_RS02605	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G6N10_RS02610	COG0217	transcriptional regulatory protein
G6N10_RS02630	COG2255	four-way junction helicase activity
G6N10_RS02635	COG1022	Amp-dependent synthetase and ligase
G6N10_RS02635	COG3320	Male sterility
G6N10_RS02655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N10_RS02660	COG0747	negative chemotaxis
G6N10_RS02670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6N10_RS02690	COG0124	histidyl-tRNA synthetase
G6N10_RS02715	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS02720	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS02755	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G6N10_RS02780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6N10_RS02785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G6N10_RS02795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6N10_RS02815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G6N10_RS02825	COG0006	proline dipeptidase activity
G6N10_RS02830	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G6N10_RS02860	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G6N10_RS02880	COG0505	Belongs to the CarA family
G6N10_RS02885	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G6N10_RS02890	COG0284	orotidine-5'-phosphate decarboxylase activity
G6N10_RS02925	COG0477	Major facilitator Superfamily
G6N10_RS02950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G6N10_RS02995	COG0477	Major facilitator Superfamily
G6N10_RS03010	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N10_RS03010	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N10_RS03015	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G6N10_RS03025	COG0322	excinuclease ABC activity
G6N10_RS03030	COG1660	Displays ATPase and GTPase activities
G6N10_RS03040	COG1481	regulation of sporulation
G6N10_RS03055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G6N10_RS03060	COG0126	phosphoglycerate kinase activity
G6N10_RS03075	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G6N10_RS03080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6N10_RS03110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6N10_RS03120	COG0109	protoheme IX farnesyltransferase activity
G6N10_RS03150	COG1131	(ABC) transporter
G6N10_RS03175	COG0396	ATPase activity
G6N10_RS03180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N10_RS03190	COG2151	metal-sulfur cluster biosynthetic enzyme
G6N10_RS03200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6N10_RS03205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N10_RS03215	COG0488	(ABC) transporter
G6N10_RS03220	COG1309	transcriptional regulator
G6N10_RS03225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6N10_RS03235	COG0791	NLP P60 protein
G6N10_RS03235	COG3883	PFAM NLP P60 protein
G6N10_RS03245	COG0714	Associated with various cellular activities
G6N10_RS03265	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6N10_RS03315	COG0604	alcohol dehydrogenase
G6N10_RS03315	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS03315	COG3321	synthase
G6N10_RS03340	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS03355	COG2149	membrane
G6N10_RS03360	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G6N10_RS03365	COG2501	S4 domain
G6N10_RS03375	COG0252	asparaginase activity
G6N10_RS03445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6N10_RS03455	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G6N10_RS03465	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G6N10_RS03475	COG0765	amino acid transport
G6N10_RS03480	COG1126	abc transporter atp-binding protein
G6N10_RS03520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N10_RS03540	COG0483	inositol monophosphate 1-phosphatase activity
G6N10_RS03545	COG0107	imidazoleglycerol-phosphate synthase activity
G6N10_RS03550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G6N10_RS03570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6N10_RS03610	COG1946	Acyl-CoA thioesterase
G6N10_RS03620	COG4988	ABC transporter
G6N10_RS03625	COG4988	ABC transporter
G6N10_RS03630	COG1294	oxidase, subunit
G6N10_RS03635	COG1271	oxidase subunit
G6N10_RS03670	COG3572	ergothioneine biosynthetic process
G6N10_RS03675	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N10_RS03685	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G6N10_RS03690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N10_RS03705	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS03780	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G6N10_RS03915	COG1872	DUF167
G6N10_RS03920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N10_RS03940	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G6N10_RS03960	COG0539	negative regulation of cytoplasmic translation
G6N10_RS03965	COG0237	dephospho-CoA kinase activity
G6N10_RS03965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6N10_RS04060	COG3328	transposase activity
G6N10_RS04095	COG1253	flavin adenine dinucleotide binding
G6N10_RS04105	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G6N10_RS04130	COG1252	NADH dehydrogenase
G6N10_RS04165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N10_RS04200	COG1024	Enoyl-CoA hydratase
G6N10_RS04230	COG1946	Acyl-CoA thioesterase
G6N10_RS04265	COG2070	2-Nitropropane dioxygenase
G6N10_RS04270	COG3250	beta-galactosidase activity
G6N10_RS04285	COG0183	Belongs to the thiolase family
G6N10_RS04310	COG3022	response to hydroperoxide
G6N10_RS04355	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G6N10_RS04380	COG0791	NLP P60 protein
G6N10_RS04380	COG3883	PFAM NLP P60 protein
G6N10_RS04390	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS04395	COG2239	Acts as a magnesium transporter
G6N10_RS04420	COG4290	ribonuclease
G6N10_RS04440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N10_RS04440	COG4651	solute:proton antiporter activity
G6N10_RS04500	COG3328	transposase activity
G6N10_RS04585	COG1309	transcriptional regulator
G6N10_RS04615	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G6N10_RS04625	COG2814	Major facilitator Superfamily
G6N10_RS04650	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
G6N10_RS04680	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G6N10_RS04760	COG0427	acetyl-CoA hydrolase
G6N10_RS04770	COG0205	6-phosphofructokinase activity
G6N10_RS04790	COG4948	Mandelate Racemase Muconate Lactonizing
G6N10_RS04800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N10_RS04805	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G6N10_RS04815	COG1309	transcriptional regulator
G6N10_RS04830	COG1846	Transcriptional regulator
G6N10_RS04865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G6N10_RS04870	COG2030	dehydratase
G6N10_RS04920	COG3757	hydrolase, family 25
G6N10_RS04950	COG2801	Transposase and inactivated derivatives
G6N10_RS04955	COG3547	Transposase (IS116 IS110 IS902 family)
G6N10_RS04960	COG2801	Transposase and inactivated derivatives
G6N10_RS05005	COG3328	transposase activity
G6N10_RS05025	COG0730	response to heat
G6N10_RS05035	COG1160	GTP binding
G6N10_RS05050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6N10_RS05070	COG0494	nUDIX hydrolase
G6N10_RS05075	COG0504	CTP synthase activity
G6N10_RS05095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G6N10_RS05105	COG0647	UMP catabolic process
G6N10_RS05135	COG2094	Belongs to the DNA glycosylase MPG family
G6N10_RS05145	COG1663	tetraacyldisaccharide 4'-kinase activity
G6N10_RS05145	COG2835	tetraacyldisaccharide 4'-kinase activity
G6N10_RS05160	COG0488	(ABC) transporter
G6N10_RS05175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N10_RS05185	COG0165	Argininosuccinate lyase
G6N10_RS05190	COG0137	argininosuccinate synthase activity
G6N10_RS05200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6N10_RS05205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6N10_RS05210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G6N10_RS05215	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G6N10_RS05220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G6N10_RS05230	COG0072	phenylalanine-tRNA ligase activity
G6N10_RS05230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6N10_RS05235	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G6N10_RS05240	COG0069	glutamate synthase activity
G6N10_RS05250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N10_RS05260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G6N10_RS05280	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G6N10_RS05280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G6N10_RS05285	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N10_RS05305	COG1950	PFAM Membrane protein of
G6N10_RS05340	COG1716	ATPase activity
G6N10_RS05380	COG3976	FMN-binding domain protein
G6N10_RS05380	COG1053	succinate dehydrogenase
G6N10_RS05390	COG4651	solute:proton antiporter activity
G6N10_RS05390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N10_RS05420	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS05445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6N10_RS05510	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6N10_RS05515	COG1177	transmembrane transport
G6N10_RS05525	COG1335	isochorismatase
G6N10_RS05545	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N10_RS05565	COG0463	Glycosyl transferase, family 2
G6N10_RS05575	COG1228	amidohydrolase
G6N10_RS05625	COG0070	glutamate synthase
G6N10_RS05625	COG0067	glutamate synthase
G6N10_RS05625	COG0069	glutamate synthase activity
G6N10_RS05630	COG0464	growth
G6N10_RS05640	COG1404	Belongs to the peptidase S8 family
G6N10_RS05650	COG2894	cell division
G6N10_RS05725	COG0300	oxidoreductase activity
G6N10_RS05770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N10_RS05775	COG2378	regulation of single-species biofilm formation
G6N10_RS05780	COG2378	regulation of single-species biofilm formation
G6N10_RS05785	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N10_RS05805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G6N10_RS05810	COG1053	succinate dehydrogenase
G6N10_RS05835	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N10_RS05845	COG4122	O-methyltransferase activity
G6N10_RS05850	COG1222	aaa ATPase
G6N10_RS05890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G6N10_RS05900	COG0477	Major facilitator Superfamily
G6N10_RS05905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6N10_RS05920	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N10_RS05925	COG0215	cysteine-tRNA ligase activity
G6N10_RS05955	COG1968	undecaprenyl-diphosphatase activity
G6N10_RS05970	COG0167	dihydroorotate dehydrogenase activity
G6N10_RS06000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N10_RS06035	COG1799	cell septum assembly
G6N10_RS06055	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G6N10_RS06060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G6N10_RS06080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G6N10_RS06090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G6N10_RS06095	COG0768	penicillin binding
G6N10_RS06105	COG0275	rRNA processing
G6N10_RS06155	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G6N10_RS06205	COG5650	phosphatidylinositol metabolic process
G6N10_RS06220	COG0003	Pfam Anion-transporting ATPase
G6N10_RS06265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G6N10_RS06270	COG1845	cytochrome c oxidase, subunit III
G6N10_RS06320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N10_RS06350	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G6N10_RS06355	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G6N10_RS06365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6N10_RS06380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6N10_RS06395	COG0321	lipoyl(octanoyl) transferase activity
G6N10_RS06400	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G6N10_RS06415	COG0174	glutamine synthetase
G6N10_RS06430	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS06445	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G6N10_RS06450	COG0174	glutamine synthetase
G6N10_RS06480	COG1024	Enoyl-CoA hydratase
G6N10_RS06655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N10_RS06690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G6N10_RS06725	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G6N10_RS06735	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G6N10_RS06740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N10_RS06745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6N10_RS06820	COG5651	PPE family
G6N10_RS06820	COG3391	amine dehydrogenase activity
G6N10_RS06875	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N10_RS06905	COG0058	SHG alpha-glucan phosphorylase activity
G6N10_RS06910	COG2252	PERMEase
G6N10_RS06915	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS06935	COG1033	growth of symbiont in host cell
G6N10_RS06935	COG2409	Drug exporters of the RND superfamily
G6N10_RS06940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N10_RS06970	COG1278	Cold shock
G6N10_RS07005	COG0395	ABC-type sugar transport system, permease component
G6N10_RS07055	COG0358	DNA primase activity
G6N10_RS07065	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G6N10_RS07075	COG0423	glycine-tRNA ligase activity
G6N10_RS07095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G6N10_RS07120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G6N10_RS07135	COG0484	heat shock protein binding
G6N10_RS07170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N10_RS07205	COG0175	sulfate reduction
G6N10_RS07220	COG4208	sulfate ABC transporter
G6N10_RS07225	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G6N10_RS07230	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G6N10_RS07240	COG3387	PFAM Glycoside hydrolase 15-related
G6N10_RS07250	COG1045	serine acetyltransferase
G6N10_RS07255	COG5398	heme oxygenase
G6N10_RS07260	COG0481	GTPase activity
G6N10_RS07295	COG1596	polysaccharide export
G6N10_RS07295	COG1555	photosystem II stabilization
G6N10_RS07305	COG2755	lipolytic protein G-D-S-L family
G6N10_RS07310	COG0406	alpha-ribazole phosphatase activity
G6N10_RS07315	COG0799	negative regulation of ribosome biogenesis
G6N10_RS07320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G6N10_RS07330	COG0542	response to heat
G6N10_RS07335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G6N10_RS07340	COG0514	ATP-dependent DNA helicase (RecQ)
G6N10_RS07345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N10_RS07365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G6N10_RS07370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6N10_RS07385	COG1530	ribonuclease E activity
G6N10_RS07390	COG0105	UTP biosynthetic process
G6N10_RS07400	COG0285	dihydrofolate synthase activity
G6N10_RS07405	COG0525	valine-tRNA ligase activity
G6N10_RS07415	COG3268	Saccharopine dehydrogenase
G6N10_RS07425	COG1388	LysM domain
G6N10_RS07430	COG1013	pyruvate-flavodoxin oxidoreductase activity
G6N10_RS07435	COG0674	pyruvate-flavodoxin oxidoreductase activity
G6N10_RS07435	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G6N10_RS07440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6N10_RS07445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G6N10_RS07450	COG0740	serine-type endopeptidase activity
G6N10_RS07460	COG0544	peptidyl-prolyl cis-trans isomerase activity
G6N10_RS07480	COG4974	Belongs to the 'phage' integrase family
G6N10_RS07485	COG0569	domain protein
G6N10_RS07485	COG2985	domain, Protein
G6N10_RS07505	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6N10_RS07545	COG0824	Thioesterase
G6N10_RS07550	COG2902	Dehydrogenase
G6N10_RS07565	COG2937	Belongs to the GPAT DAPAT family
G6N10_RS07635	COG1982	Orn Lys Arg decarboxylase major
G6N10_RS07645	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS07660	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N10_RS07665	COG3707	response regulator
G6N10_RS07685	COG2354	Protein conserved in bacteria
G6N10_RS07695	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N10_RS07720	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS07730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N10_RS07745	COG4221	oxidoreductase activity
G6N10_RS07750	COG1742	UPF0060 membrane protein
G6N10_RS07770	COG0433	COG0433 Predicted ATPase
G6N10_RS07785	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
G6N10_RS07790	COG1021	2,3-dihydroxybenzoate-AMP ligase
G6N10_RS07795	COG1169	isochorismate synthase
G6N10_RS07800	COG1376	ErfK ybiS ycfS ynhG family protein
G6N10_RS07845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G6N10_RS07890	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G6N10_RS07900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N10_RS07915	COG0110	maltose O-acetyltransferase activity
G6N10_RS07920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N10_RS07930	COG1115	amino acid carrier protein
G6N10_RS07955	COG1119	ATPase activity
G6N10_RS07980	COG1064	alcohol dehydrogenase
G6N10_RS07995	COG1309	transcriptional regulator
G6N10_RS08000	COG0644	oxidoreductase
G6N10_RS08020	COG0300	oxidoreductase activity
G6N10_RS08030	COG2258	MOSC domain
G6N10_RS08035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N10_RS08085	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6N10_RS08090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6N10_RS08105	COG0431	NADPH-dependent FMN reductase
G6N10_RS08140	COG1937	Protein conserved in bacteria
G6N10_RS08145	COG0730	response to heat
G6N10_RS08155	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS08165	COG1966	Carbon starvation protein
G6N10_RS08185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N10_RS08205	COG4221	oxidoreductase activity
G6N10_RS08220	COG0488	(ABC) transporter
G6N10_RS08230	COG0477	Major facilitator Superfamily
G6N10_RS08245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G6N10_RS08275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N10_RS08355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G6N10_RS08360	COG2177	Part of the ABC transporter FtsEX involved in
G6N10_RS08365	COG2884	Cell division ATP-binding protein ftsE
G6N10_RS08375	COG0668	transmembrane transport
G6N10_RS08390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6N10_RS08395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N10_RS08405	COG0483	inositol monophosphate 1-phosphatase activity
G6N10_RS08415	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS08430	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G6N10_RS08440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N10_RS08445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N10_RS08470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N10_RS08475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N10_RS08495	COG1034	ATP synthesis coupled electron transport
G6N10_RS08500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G6N10_RS08505	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N10_RS08515	COG0713	ATP synthesis coupled electron transport
G6N10_RS08555	COG4638	Rieske (2fe-2S)
G6N10_RS08575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N10_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS08615	COG1063	alcohol dehydrogenase
G6N10_RS08635	COG0604	alcohol dehydrogenase
G6N10_RS08645	COG2267	carboxylic ester hydrolase activity
G6N10_RS08655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N10_RS08665	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G6N10_RS08670	COG2326	polyphosphate kinase activity
G6N10_RS08675	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS08690	COG1525	nuclease
G6N10_RS08700	COG2226	methyltransferase
G6N10_RS08715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N10_RS08725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N10_RS08730	COG0798	PFAM Bile acid sodium symporter
G6N10_RS08735	COG0640	Transcriptional regulator
G6N10_RS08740	COG0640	Transcriptional regulator
G6N10_RS08760	COG0582	viral genome integration into host DNA
G6N10_RS08795	COG4942	peptidase
G6N10_RS08915	COG1397	ADP-ribosylglycohydrolase
G6N10_RS08920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G6N10_RS08930	COG1061	Type III restriction enzyme res subunit
G6N10_RS09005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G6N10_RS09135	COG1615	UPF0182 protein
G6N10_RS09140	COG3480	Lon protease (S16) C-terminal proteolytic domain
G6N10_RS09155	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N10_RS09195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N10_RS09215	COG2814	Major facilitator Superfamily
G6N10_RS09220	COG0596	Alpha beta hydrolase
G6N10_RS09280	COG0513	Belongs to the DEAD box helicase family
G6N10_RS09310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G6N10_RS09320	COG1597	lipid kinase activity
G6N10_RS09335	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N10_RS09345	COG5662	AntiSigma factor
G6N10_RS09355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G6N10_RS09365	COG2226	methyltransferase
G6N10_RS09370	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N10_RS09375	COG2135	peptidase activity
G6N10_RS09380	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6N10_RS09385	COG1162	GTPase activity
G6N10_RS09410	COG2326	polyphosphate kinase activity
G6N10_RS09430	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G6N10_RS09440	COG5401	PFAM Sporulation and spore germination
G6N10_RS09445	COG5002	protein histidine kinase activity
G6N10_RS09475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N10_RS09485	COG0531	amino acid
G6N10_RS09500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N10_RS09520	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G6N10_RS09525	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G6N10_RS09525	COG0778	Nitroreductase
G6N10_RS09545	COG1091	dTDP-4-dehydrorhamnose reductase activity
G6N10_RS09550	COG1316	TRANSCRIPTIONal
G6N10_RS09570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G6N10_RS09590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N10_RS09615	COG4770	biotin carboxylase activity
G6N10_RS09625	COG0039	L-malate dehydrogenase activity
G6N10_RS09645	COG1918	ferrous iron import across plasma membrane
G6N10_RS09645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G6N10_RS09655	COG0316	Belongs to the HesB IscA family
G6N10_RS09655	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G6N10_RS09660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N10_RS09670	COG1201	RNA secondary structure unwinding
G6N10_RS09695	COG0564	pseudouridine synthase activity
G6N10_RS09715	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N10_RS09715	COG1473	amidohydrolase
G6N10_RS09725	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G6N10_RS09750	COG2009	succinate dehydrogenase
G6N10_RS09765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G6N10_RS09770	COG1024	Enoyl-CoA hydratase
G6N10_RS09775	COG1686	Belongs to the peptidase S11 family
G6N10_RS09780	COG2070	2-Nitropropane dioxygenase
G6N10_RS09800	COG0708	Exodeoxyribonuclease III
G6N10_RS09810	COG2873	o-acetylhomoserine
G6N10_RS09835	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N10_RS09835	COG1902	pentaerythritol trinitrate reductase activity
G6N10_RS09840	COG0842	Transport permease protein
G6N10_RS09840	COG1131	(ABC) transporter
G6N10_RS09840	COG1716	ATPase activity
G6N10_RS09845	COG1357	PFAM Pentapeptide repeats (8 copies)
G6N10_RS09850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6N10_RS09870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N10_RS09870	COG0574	Belongs to the PEP-utilizing enzyme family
G6N10_RS09895	COG1946	Acyl-CoA thioesterase
G6N10_RS09935	COG0519	Catalyzes the synthesis of GMP from XMP
G6N10_RS09935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6N10_RS09945	COG0516	GMP reductase activity
G6N10_RS09980	COG1834	amidinotransferase
G6N10_RS10040	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G6N10_RS10065	COG0456	acetyltransferase
G6N10_RS10070	COG0456	acetyltransferase
G6N10_RS10070	COG1214	PFAM Peptidase M22, glycoprotease
G6N10_RS10085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G6N10_RS10090	COG0076	glutamate decarboxylase activity
G6N10_RS10100	COG0390	transport system, permease component
G6N10_RS10110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6N10_RS10130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N10_RS10140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G6N10_RS10165	COG4303	Ethanolamine ammonia lyase large subunit
G6N10_RS10170	COG0531	amino acid
G6N10_RS10200	COG1674	ftsk spoiiie
G6N10_RS10210	COG1404	Belongs to the peptidase S8 family
G6N10_RS10255	COG0203	ribosomal protein L17
G6N10_RS10270	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G6N10_RS10275	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G6N10_RS10280	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G6N10_RS10285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G6N10_RS10295	COG2268	Band 7 protein
G6N10_RS10305	COG1088	dTDP-glucose 4,6-dehydratase activity
G6N10_RS10320	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS10340	COG0563	adenylate kinase activity
G6N10_RS10350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N10_RS10355	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N10_RS10365	COG0616	signal peptide processing
G6N10_RS10380	COG0200	Binds to the 23S rRNA
G6N10_RS10390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G6N10_RS10395	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G6N10_RS10400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G6N10_RS10405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G6N10_RS10410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6N10_RS10420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G6N10_RS10425	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G6N10_RS10440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G6N10_RS10445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G6N10_RS10465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N10_RS10500	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G6N10_RS10505	COG0255	Belongs to the universal ribosomal protein uL29 family
G6N10_RS10520	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G6N10_RS10525	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G6N10_RS10530	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G6N10_RS10540	COG0088	Forms part of the polypeptide exit tunnel
G6N10_RS10545	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G6N10_RS10550	COG0051	transcription antitermination factor activity, RNA binding
G6N10_RS10570	COG0477	Major facilitator Superfamily
G6N10_RS10600	COG0535	radical SAM domain protein
G6N10_RS10620	COG1522	sequence-specific DNA binding
G6N10_RS10625	COG1834	amidinotransferase
G6N10_RS10630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6N10_RS10635	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS10640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G6N10_RS10645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G6N10_RS10650	COG0049	tRNA binding
G6N10_RS10655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G6N10_RS10675	COG1024	Enoyl-CoA hydratase
G6N10_RS10690	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS10700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6N10_RS10725	COG0222	ribosome binding
G6N10_RS10730	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G6N10_RS10755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N10_RS10760	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
G6N10_RS10765	COG0081	regulation of translation
G6N10_RS10770	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G6N10_RS10780	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G6N10_RS10795	COG2030	dehydratase
G6N10_RS10800	COG2030	dehydratase
G6N10_RS10820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N10_RS10820	COG1017	nitric oxide dioxygenase activity
G6N10_RS10825	COG1959	2 iron, 2 sulfur cluster binding
G6N10_RS10830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N10_RS10845	COG1376	ErfK ybiS ycfS ynhG family protein
G6N10_RS10860	COG1666	GTP binding
G6N10_RS10865	COG2072	flavoprotein involved in K transport
G6N10_RS10885	COG0501	Belongs to the peptidase M48B family
G6N10_RS10905	COG2226	methyltransferase
G6N10_RS10910	COG0438	transferase activity, transferring glycosyl groups
G6N10_RS10930	COG4948	Mandelate Racemase Muconate Lactonizing
G6N10_RS10935	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS10945	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6N10_RS10950	COG4221	oxidoreductase activity
G6N10_RS10995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N10_RS11005	COG0785	Cytochrome C biogenesis protein
G6N10_RS11015	COG0406	alpha-ribazole phosphatase activity
G6N10_RS11020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G6N10_RS11025	COG1396	sequence-specific DNA binding
G6N10_RS11030	COG0235	Class ii aldolase
G6N10_RS11035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N10_RS11075	COG1587	Uroporphyrinogen-III synthase
G6N10_RS11075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N10_RS11080	COG0181	hydroxymethylbilane synthase activity
G6N10_RS11085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G6N10_RS11100	COG2030	dehydratase
G6N10_RS11150	COG0745	RESPONSE REGULATOR receiver
G6N10_RS11155	COG5002	protein histidine kinase activity
G6N10_RS11170	COG0438	transferase activity, transferring glycosyl groups
G6N10_RS11235	COG2733	membrane
G6N10_RS11245	COG2326	polyphosphate kinase activity
G6N10_RS11250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N10_RS11280	COG0415	Belongs to the DNA photolyase family
G6N10_RS11300	COG1505	serine-type exopeptidase activity
G6N10_RS11335	COG0459	protein refolding
G6N10_RS11360	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS11375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N10_RS11380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6N10_RS11380	COG2111	Na H antiporter
G6N10_RS11385	COG1006	Multisubunit Na H antiporter MnhC subunit
G6N10_RS11400	COG2212	antiporter activity
G6N10_RS11405	COG1320	monovalent cation:proton antiporter activity
G6N10_RS11410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G6N10_RS11420	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N10_RS11440	COG0242	peptide deformylase activity
G6N10_RS11460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G6N10_RS11465	COG0351	phosphomethylpyrimidine kinase
G6N10_RS11495	COG2234	aminopeptidase activity
G6N10_RS11500	COG2234	aminopeptidase activity
G6N10_RS11515	COG2022	thiamine diphosphate biosynthetic process
G6N10_RS11525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N10_RS11535	COG0352	thiamine-phosphate diphosphorylase activity
G6N10_RS11550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N10_RS11555	COG0515	serine threonine protein kinase
G6N10_RS11610	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G6N10_RS11620	COG1994	Peptidase M50
G6N10_RS11640	COG0586	Pfam SNARE associated Golgi protein
G6N10_RS11660	COG1845	cytochrome c oxidase, subunit III
G6N10_RS11685	COG2124	cytochrome p450
G6N10_RS11695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N10_RS11725	COG1704	LemA family
G6N10_RS11730	COG0542	response to heat
G6N10_RS11755	COG0789	Transcriptional regulator
G6N10_RS11765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6N10_RS11770	COG0443	Heat shock 70 kDa protein
G6N10_RS11780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N10_RS11830	COG0247	lactate metabolic process
G6N10_RS11830	COG2181	nitrate reductase activity
G6N10_RS11850	COG3620	sequence-specific DNA binding
G6N10_RS11880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N10_RS11890	COG0717	Belongs to the dCTP deaminase family
G6N10_RS12000	COG1404	Belongs to the peptidase S8 family
G6N10_RS12015	COG4842	Belongs to the WXG100 family
G6N10_RS12040	COG3266	domain, Protein
G6N10_RS12045	COG0464	growth
G6N10_RS12050	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N10_RS12080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N10_RS12100	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS12105	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS12115	COG1012	belongs to the aldehyde dehydrogenase family
G6N10_RS12130	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS12160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G6N10_RS12165	COG1984	allophanate hydrolase subunit 2
G6N10_RS12185	COG1053	succinate dehydrogenase
G6N10_RS12205	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS12210	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS12215	COG0183	Belongs to the thiolase family
G6N10_RS12220	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS12225	COG2030	dehydratase
G6N10_RS12235	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N10_RS12240	COG0589	response to stress
G6N10_RS12250	COG4981	capsule polysaccharide biosynthetic process
G6N10_RS12255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N10_RS12255	COG2755	lipolytic protein G-D-S-L family
G6N10_RS12275	COG0500	methyltransferase
G6N10_RS12285	COG3599	regulation of cell shape
G6N10_RS12295	COG0183	Belongs to the thiolase family
G6N10_RS12320	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS12330	COG1024	Enoyl-CoA hydratase
G6N10_RS12365	COG1024	Enoyl-CoA hydratase
G6N10_RS12425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G6N10_RS12435	COG2409	Drug exporters of the RND superfamily
G6N10_RS12470	COG2409	Drug exporters of the RND superfamily
G6N10_RS12490	COG3590	peptidase
G6N10_RS12505	COG1376	ErfK ybiS ycfS ynhG family protein
G6N10_RS12510	COG1937	Protein conserved in bacteria
G6N10_RS12535	COG4122	O-methyltransferase activity
G6N10_RS12555	COG1358	cellular component organization or biogenesis
G6N10_RS12610	COG2267	carboxylic ester hydrolase activity
G6N10_RS12615	COG0039	L-malate dehydrogenase activity
G6N10_RS12640	COG1309	transcriptional regulator
G6N10_RS12645	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G6N10_RS12650	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G6N10_RS12660	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS12680	COG5651	PPE family
G6N10_RS12680	COG3391	amine dehydrogenase activity
G6N10_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS12695	COG1012	belongs to the aldehyde dehydrogenase family
G6N10_RS12700	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N10_RS12720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N10_RS12730	COG1105	Belongs to the carbohydrate kinase PfkB family
G6N10_RS12735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6N10_RS12735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6N10_RS12775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N10_RS12800	COG1063	alcohol dehydrogenase
G6N10_RS12810	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS12850	COG1074	ATP-dependent DNA helicase activity
G6N10_RS12855	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G6N10_RS12875	COG3842	ATPase activity
G6N10_RS12895	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N10_RS12900	COG1376	ErfK ybiS ycfS ynhG family protein
G6N10_RS12915	COG1309	transcriptional regulator
G6N10_RS12920	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS12935	COG0477	Major facilitator Superfamily
G6N10_RS12940	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS12945	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS12955	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS12970	COG2072	flavoprotein involved in K transport
G6N10_RS12985	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS12995	COG2188	Transcriptional regulator
G6N10_RS13000	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS13010	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS13030	COG0705	Rhomboid family
G6N10_RS13065	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS13080	COG2124	cytochrome p450
G6N10_RS13105	COG1309	transcriptional regulator
G6N10_RS13135	COG1643	Atp-dependent helicase
G6N10_RS13155	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS13185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N10_RS13190	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS13220	COG0346	lactoylglutathione lyase activity
G6N10_RS13235	COG2124	cytochrome p450
G6N10_RS13245	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS13255	COG0183	Belongs to the thiolase family
G6N10_RS13265	COG1376	ErfK ybiS ycfS ynhG family protein
G6N10_RS13275	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS13290	COG0386	Belongs to the glutathione peroxidase family
G6N10_RS13295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N10_RS13395	COG0640	Transcriptional regulator
G6N10_RS13400	COG0798	PFAM Bile acid sodium symporter
G6N10_RS13430	COG0360	Binds together with S18 to 16S ribosomal RNA
G6N10_RS13445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N10_RS13465	COG1260	myo-inositol-1-phosphate synthase
G6N10_RS13485	COG4221	oxidoreductase activity
G6N10_RS13505	COG1678	Uncharacterized ACR, COG1678
G6N10_RS13565	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N10_RS13565	COG3409	Peptidoglycan-binding domain 1 protein
G6N10_RS13580	COG1192	Involved in chromosome partitioning
G6N10_RS13585	COG0357	Ribosomal RNA small subunit methyltransferase G
G6N10_RS13590	COG1847	R3H domain protein
G6N10_RS13600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G6N10_RS13610	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G6N10_RS13615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G6N10_RS13620	COG0592	DNA-directed DNA polymerase activity
G6N10_RS13625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6N10_RS13630	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G6N10_RS13635	COG0187	DNA topoisomerase II activity
G6N10_RS13705	COG0515	serine threonine protein kinase
G6N10_RS13725	COG1716	ATPase activity
G6N10_RS13730	COG1716	ATPase activity
G6N10_RS13800	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS13810	COG1297	OPT oligopeptide transporter protein
G6N10_RS13875	COG1674	ftsk spoiiie
G6N10_RS13885	COG3321	synthase
G6N10_RS13885	COG0604	alcohol dehydrogenase
G6N10_RS13895	COG0183	Belongs to the thiolase family
G6N10_RS13900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N10_RS13905	COG1309	transcriptional regulator
G6N10_RS13910	COG2072	flavoprotein involved in K transport
G6N10_RS13915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6N10_RS13950	COG1528	Iron-storage protein
G6N10_RS13955	COG1528	Iron-storage protein
G6N10_RS13960	COG1316	TRANSCRIPTIONal
G6N10_RS14010	COG2146	nitrite reductase [NAD(P)H] activity
G6N10_RS14010	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G6N10_RS14030	COG0561	phosphatase activity
G6N10_RS14050	COG1216	Glycosyl transferase, family 2
G6N10_RS14065	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N10_RS14085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N10_RS14110	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS14115	COG0277	FAD linked oxidase domain protein
G6N10_RS14150	COG1216	Glycosyl transferase, family 2
G6N10_RS14210	COG1484	DNA-dependent DNA replication
G6N10_RS14315	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS14325	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G6N10_RS14330	COG2226	methyltransferase
G6N10_RS14335	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS14345	COG0745	RESPONSE REGULATOR receiver
G6N10_RS14350	COG2205	protein histidine kinase activity
G6N10_RS14360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N10_RS14375	COG5416	Lipopolysaccharide assembly protein A domain
G6N10_RS14385	COG0287	Prephenate dehydrogenase
G6N10_RS14395	COG0590	tRNA wobble adenosine to inosine editing
G6N10_RS14520	COG3311	Transcriptional regulator
G6N10_RS14620	COG1674	ftsk spoiiie
G6N10_RS14700	COG0604	alcohol dehydrogenase
G6N10_RS14725	COG0343	queuine tRNA-ribosyltransferase activity
G6N10_RS14730	COG2124	cytochrome p450
G6N10_RS14735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N10_RS14765	COG1309	transcriptional regulator
G6N10_RS14780	COG1793	dna ligase
G6N10_RS14790	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G6N10_RS14795	COG1793	dna ligase
G6N10_RS14810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N10_RS14830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N10_RS14855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N10_RS14870	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N10_RS14880	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G6N10_RS14900	COG1309	transcriptional regulator
G6N10_RS14910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N10_RS14950	COG0778	Nitroreductase
G6N10_RS14965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6N10_RS14995	COG0714	Associated with various cellular activities
G6N10_RS15020	COG0477	Major facilitator Superfamily
G6N10_RS15025	COG1309	transcriptional regulator
G6N10_RS15140	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS15165	COG2072	flavoprotein involved in K transport
G6N10_RS15240	COG1024	Enoyl-CoA hydratase
G6N10_RS15260	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N10_RS15270	COG0633	Ferredoxin
G6N10_RS15290	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS15365	COG4974	Belongs to the 'phage' integrase family
G6N10_RS15370	COG0582	viral genome integration into host DNA
G6N10_RS15535	COG1408	metallophosphoesterase
G6N10_RS15540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N10_RS15570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N10_RS15620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N10_RS15670	COG1111	helicase
G6N10_RS15670	COG1205	dead DEAH box helicase
G6N10_RS15675	COG1278	Cold shock
G6N10_RS15685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G6N10_RS15685	COG1754	DNA topoisomerase type I activity
G6N10_RS15695	COG0470	DNA polymerase III
G6N10_RS15740	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N10_RS15760	COG0789	Transcriptional regulator
G6N10_RS15765	COG0659	secondary active sulfate transmembrane transporter activity
G6N10_RS15770	COG0640	Transcriptional regulator
G6N10_RS15775	COG0798	PFAM Bile acid sodium symporter
G6N10_RS15780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N10_RS15785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N10_RS15790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N10_RS15830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G6N10_RS15830	COG0493	'glutamate synthase
G6N10_RS15835	COG3177	Filamentation induced by cAMP protein fic
G6N10_RS15870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N10_RS15940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G6N10_RS15945	COG2027	D-alanyl-D-alanine carboxypeptidase
G6N10_RS15955	COG0037	tRNA processing
G6N10_RS15970	COG2267	carboxylic ester hydrolase activity
G6N10_RS15980	COG0302	gtp cyclohydrolase
G6N10_RS15985	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G6N10_RS15990	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G6N10_RS16020	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G6N10_RS16025	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G6N10_RS16030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G6N10_RS16040	COG0542	response to heat
G6N10_RS16080	COG1194	a g-specific adenine glycosylase
G6N10_RS16085	COG0288	reversible hydration of carbon dioxide
G6N10_RS16095	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G6N10_RS16100	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G6N10_RS16105	COG2847	Copper chaperone PCu(A)C
G6N10_RS16110	COG1329	Transcriptional regulator
G6N10_RS16115	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6N10_RS16130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N10_RS16150	COG1121	(ABC) transporter
G6N10_RS16160	COG1609	Transcriptional regulator
G6N10_RS16165	COG1877	trehalose-phosphatase activity
G6N10_RS16165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6N10_RS16170	COG1309	transcriptional regulator
G6N10_RS16175	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS16185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N10_RS16215	COG0436	Aminotransferase
G6N10_RS16220	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS16225	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS16230	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS16235	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS16240	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS16320	COG1100	Small GTP-binding protein
G6N10_RS16330	COG0183	Belongs to the thiolase family
G6N10_RS16365	COG1024	Enoyl-CoA hydratase
G6N10_RS16375	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS16380	COG0406	alpha-ribazole phosphatase activity
G6N10_RS16400	COG0183	Belongs to the thiolase family
G6N10_RS16405	COG2124	cytochrome p450
G6N10_RS16410	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS16415	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS16440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N10_RS16450	COG1231	oxidoreductase activity
G6N10_RS16505	COG2226	methyltransferase
G6N10_RS16515	COG0640	Transcriptional regulator
G6N10_RS16520	COG5002	protein histidine kinase activity
G6N10_RS16525	COG0745	RESPONSE REGULATOR receiver
G6N10_RS16550	COG2132	Multicopper oxidase
G6N10_RS16555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N10_RS16575	COG2217	Heavy metal translocating P-type atpase
G6N10_RS16665	COG2030	dehydratase
G6N10_RS16670	COG1053	succinate dehydrogenase
G6N10_RS16675	COG3971	2-oxopent-4-enoate hydratase activity
G6N10_RS16680	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G6N10_RS16685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N10_RS16710	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS16720	COG0450	alkyl hydroperoxide reductase
G6N10_RS16725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N10_RS16735	COG4638	Rieske (2fe-2S)
G6N10_RS16755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N10_RS16765	COG2124	cytochrome p450
G6N10_RS16780	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS16785	COG2070	2-Nitropropane dioxygenase
G6N10_RS16790	COG0028	Belongs to the TPP enzyme family
G6N10_RS16795	COG0167	dihydroorotate dehydrogenase activity
G6N10_RS16805	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS16810	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS16815	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS16825	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS16835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N10_RS16860	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N10_RS16885	COG1024	Enoyl-CoA hydratase
G6N10_RS16940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N10_RS16950	COG1316	TRANSCRIPTIONal
G6N10_RS16960	COG0531	amino acid
G6N10_RS16980	COG0745	RESPONSE REGULATOR receiver
G6N10_RS16985	COG2205	protein histidine kinase activity
G6N10_RS17010	COG2124	cytochrome p450
G6N10_RS17120	COG2072	flavoprotein involved in K transport
G6N10_RS17135	COG1028	Short-chain dehydrogenase reductase Sdr
G6N10_RS17140	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS17145	COG0183	Belongs to the thiolase family
G6N10_RS17150	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS17160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N10_RS17170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N10_RS17180	COG1609	Transcriptional regulator
G6N10_RS17185	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS17195	COG1024	Enoyl-CoA hydratase
G6N10_RS17200	COG1024	Enoyl-CoA hydratase
G6N10_RS17205	COG1024	Enoyl-CoA hydratase
G6N10_RS17210	COG1024	Enoyl-CoA hydratase
G6N10_RS17220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N10_RS17225	COG1024	Enoyl-CoA hydratase
G6N10_RS17235	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS17250	COG1960	acyl-CoA dehydrogenase activity
G6N10_RS17260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N10_RS17305	COG2072	flavoprotein involved in K transport
G6N10_RS17340	COG0825	malonyl-CoA metabolic process
G6N10_RS17340	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G6N10_RS17350	COG4221	oxidoreductase activity
G6N10_RS17370	COG3226	Transcriptional regulator
G6N10_RS17375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N10_RS17400	COG3573	Dehydrogenase
G6N10_RS17410	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N10_RS17420	COG1362	aminopeptidase activity
G6N10_RS17465	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G6N10_RS17490	COG4044	May play a role in the intracellular transport of hydrophobic ligands
G6N10_RS17515	COG0745	RESPONSE REGULATOR receiver
G6N10_RS17535	COG0581	inorganic phosphate transmembrane transporter activity
G6N10_RS17540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6N10_RS17575	COG0515	serine threonine protein kinase
G6N10_RS17645	COG1917	Cupin 2, conserved barrel domain protein
G6N10_RS17645	COG2169	Transcriptional regulator
G6N10_RS17695	COG1902	pentaerythritol trinitrate reductase activity
G6N10_RS17695	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N10_RS17700	COG4221	oxidoreductase activity
G6N10_RS17735	COG2072	flavoprotein involved in K transport
G6N10_RS17765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N10_RS17785	COG0183	Belongs to the thiolase family
G6N10_RS17790	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N10_RS17790	COG1024	Enoyl-CoA hydratase
G6N10_RS17800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N10_RS17805	COG2070	2-Nitropropane dioxygenase
G6N10_RS17840	COG1278	Cold shock
G6N10_RS17850	COG2814	Major facilitator Superfamily
G6N10_RS17885	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G6N10_RS17900	COG0259	pyridoxamine-phosphate oxidase activity
G6N10_RS17905	COG1309	transcriptional regulator
G6N10_RS17915	COG0545	Peptidyl-prolyl cis-trans isomerase
G6N10_RS17920	COG2205	protein histidine kinase activity
G6N10_RS17935	COG1131	(ABC) transporter
G6N10_RS17945	COG1024	Enoyl-CoA hydratase
G6N10_RS17955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N10_RS17990	COG1263	PTS System
G6N10_RS17990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6N10_RS17990	COG2190	(PTS) system
G6N10_RS17995	COG2190	(PTS) system
G6N10_RS18000	COG0363	glucosamine-6-phosphate deaminase activity
G6N10_RS18010	COG1113	amino acid transport
G6N10_RS18025	COG0300	oxidoreductase activity
G6N10_RS18085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N10_RS18095	COG0166	Belongs to the GPI family
G6N10_RS18130	COG0045	succinate-CoA ligase (ADP-forming) activity
G6N10_RS18175	COG3781	membrane
G6N10_RS18185	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
G6N10_RS18230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N10_RS18260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N10_RS18265	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N10_RS18265	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N10_RS18280	COG0659	secondary active sulfate transmembrane transporter activity
G6N10_RS18285	COG2205	protein histidine kinase activity
G6N10_RS18290	COG0745	RESPONSE REGULATOR receiver
G6N10_RS18320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6N10_RS18325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6N10_RS18365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N10_RS18365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N10_RS18370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6N10_RS18395	COG2235	arginine
G6N10_RS18420	COG1595	DNA-templated transcription, initiation
G6N10_RS18430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G6N10_RS18440	COG0084	hydrolase, TatD family'
G6N10_RS18455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G6N10_RS18460	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS18490	COG0193	aminoacyl-tRNA hydrolase activity
G6N10_RS18495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G6N10_RS18505	COG1393	Belongs to the ArsC family
G6N10_RS18525	COG1309	transcriptional regulator
G6N10_RS18540	COG3956	TIGRFAM MazG family protein
G6N10_RS18545	COG2837	iron assimilation
G6N10_RS18590	COG2337	Toxic component of a toxin-antitoxin (TA) module
G6N10_RS18600	COG1522	sequence-specific DNA binding
G6N10_RS18625	COG4585	Histidine kinase
G6N10_RS18650	COG3804	dihydrodipicolinate reductase
G6N10_RS18655	COG0121	glutamine amidotransferase
G6N10_RS18685	COG0183	Belongs to the thiolase family
G6N10_RS18690	COG2755	lipolytic protein G-D-S-L family
G6N10_RS18695	COG0657	acetylesterase activity
G6N10_RS18715	COG5473	translation initiation factor activity
G6N10_RS18730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6N10_RS18740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N10_RS18750	COG1331	Highly conserved protein containing a thioredoxin domain
G6N10_RS18755	COG3631	Ketosteroid isomerase-related protein
G6N10_RS18765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G6N10_RS18770	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS18795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6N10_RS18805	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G6N10_RS18855	COG1722	exodeoxyribonuclease VII activity
G6N10_RS18860	COG1570	exodeoxyribonuclease VII activity
G6N10_RS18870	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G6N10_RS18880	COG0012	GTP binding
G6N10_RS18925	COG2267	carboxylic ester hydrolase activity
G6N10_RS18955	COG1024	Enoyl-CoA hydratase
G6N10_RS18970	COG1024	Enoyl-CoA hydratase
G6N10_RS18975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N10_RS18990	COG2409	Drug exporters of the RND superfamily
G6N10_RS19005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G6N10_RS19010	COG1725	Transcriptional regulator
G6N10_RS19020	COG3467	pyridoxamine 5'-phosphate
G6N10_RS19065	COG1051	belongs to the nudix hydrolase family
G6N10_RS19070	COG2154	pterin-4-alpha-carbinolamine dehydratase
G6N10_RS19110	COG3654	unkown
G6N10_RS19125	COG0747	negative chemotaxis
G6N10_RS19185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N10_RS19190	COG2337	Toxic component of a toxin-antitoxin (TA) module
G6N10_RS19260	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N10_RS19260	COG1902	pentaerythritol trinitrate reductase activity
G6N10_RS19265	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6N10_RS19280	COG1012	belongs to the aldehyde dehydrogenase family
G6N10_RS19285	COG0506	proline dehydrogenase activity
G6N10_RS19290	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS19300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N10_RS19305	COG1611	Belongs to the LOG family
G6N10_RS19310	COG0318	PFAM AMP-dependent synthetase and ligase
G6N10_RS19320	COG0463	Glycosyl transferase, family 2
G6N10_RS19330	COG0519	Catalyzes the synthesis of GMP from XMP
G6N10_RS19340	COG0297	glycogen (starch) synthase activity
G6N10_RS19345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G6N10_RS19355	COG3559	Exporter of polyketide antibiotics
G6N10_RS19360	COG1131	(ABC) transporter
G6N10_RS19365	COG1309	transcriptional regulator
G6N10_RS19375	COG1595	DNA-templated transcription, initiation
G6N10_RS19380	COG5662	AntiSigma factor
G6N10_RS19385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N10_RS19390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N10_RS19410	COG2239	Acts as a magnesium transporter
G6N10_RS19415	COG2301	Belongs to the HpcH HpaI aldolase family
G6N10_RS19455	COG0598	Magnesium transport protein CorA
G6N10_RS19470	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N10_RS19470	COG0567	Dehydrogenase, E1 component
G6N10_RS19485	COG0277	FAD linked oxidase domain protein
G6N10_RS19515	COG0277	FAD linked oxidase domain protein
G6N10_RS19530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N10_RS19665	COG0366	Alpha amylase catalytic
G6N10_RS19675	COG0243	molybdopterin cofactor binding
G6N10_RS19680	COG2146	nitrite reductase [NAD(P)H] activity
G6N10_RS19680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N10_RS19685	COG2146	nitrite reductase [NAD(P)H] activity
G6N10_RS19685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N10_RS19725	COG3237	CsbD-like
G6N10_RS19770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G6N10_RS19775	COG2321	neutral zinc metallopeptidase
G6N10_RS19810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6N10_RS19810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6N10_RS19860	COG1674	ftsk spoiiie
G6N10_RS19915	COG0582	viral genome integration into host DNA
G6N10_RS19925	COG0018	arginyl-trna synthetase
G6N10_RS19935	COG0460	homoserine dehydrogenase