locus-tag	class	description
NTM_RS00015	COG1595	DNA-templated transcription, initiation
NTM_RS00045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NTM_RS00065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NTM_RS00070	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS00080	COG1408	metallophosphoesterase
NTM_RS00085	COG1686	Belongs to the peptidase S11 family
NTM_RS00090	COG1295	ribonuclease BN
NTM_RS00135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NTM_RS00140	COG0446	pyridine nucleotide-disulphide oxidoreductase
NTM_RS00140	COG1902	pentaerythritol trinitrate reductase activity
NTM_RS00150	COG1716	ATPase activity
NTM_RS00150	COG0842	Transport permease protein
NTM_RS00150	COG1131	(ABC) transporter
NTM_RS00160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NTM_RS00160	COG1017	nitric oxide dioxygenase activity
NTM_RS00165	COG1357	PFAM Pentapeptide repeats (8 copies)
NTM_RS00180	COG2018	Roadblock/LC7 domain
NTM_RS00185	COG5002	protein histidine kinase activity
NTM_RS00190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NTM_RS00200	COG0587	DNA-directed DNA polymerase activity
NTM_RS00210	COG2030	dehydratase
NTM_RS00215	COG1715	Restriction endonuclease
NTM_RS00215	COG1787	Restriction endonuclease
NTM_RS00255	COG4584	PFAM Integrase catalytic
NTM_RS00305	COG1082	Xylose isomerase domain protein TIM barrel
NTM_RS00330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS00335	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS00365	COG0604	alcohol dehydrogenase
NTM_RS00420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS00425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS00440	COG2072	flavoprotein involved in K transport
NTM_RS00445	COG2267	carboxylic ester hydrolase activity
NTM_RS00450	COG0778	Nitroreductase
NTM_RS00455	COG1960	acyl-CoA dehydrogenase activity
NTM_RS00460	COG1960	acyl-CoA dehydrogenase activity
NTM_RS00465	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS00470	COG0183	Belongs to the thiolase family
NTM_RS00475	COG1024	Enoyl-CoA hydratase
NTM_RS00475	COG1250	3-hydroxyacyl-CoA dehydrogenase
NTM_RS00485	COG1064	alcohol dehydrogenase
NTM_RS00565	COG0519	Catalyzes the synthesis of GMP from XMP
NTM_RS00565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NTM_RS00595	COG0516	GMP reductase activity
NTM_RS00645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NTM_RS00675	COG0277	FAD linked oxidase domain protein
NTM_RS00680	COG0459	protein refolding
NTM_RS00685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NTM_RS00690	COG1403	HNH endonuclease
NTM_RS00695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NTM_RS00700	COG0456	acetyltransferase
NTM_RS00705	COG0456	acetyltransferase
NTM_RS00705	COG1214	PFAM Peptidase M22, glycoprotease
NTM_RS00720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NTM_RS00725	COG0076	glutamate decarboxylase activity
NTM_RS00745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NTM_RS00755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS00765	COG1960	acyl-CoA dehydrogenase activity
NTM_RS00785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NTM_RS00795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NTM_RS00800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NTM_RS00825	COG4842	Belongs to the WXG100 family
NTM_RS00830	COG4842	Belongs to the WXG100 family
NTM_RS00840	COG1674	ftsk spoiiie
NTM_RS00850	COG1404	Belongs to the peptidase S8 family
NTM_RS00890	COG0203	ribosomal protein L17
NTM_RS00895	COG0202	RNA polymerase activity
NTM_RS00900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NTM_RS00905	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NTM_RS00910	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NTM_RS00915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NTM_RS00920	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NTM_RS00935	COG0574	Belongs to the PEP-utilizing enzyme family
NTM_RS00935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NTM_RS00940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NTM_RS00965	COG1063	alcohol dehydrogenase
NTM_RS00990	COG3852	Histidine kinase
NTM_RS01010	COG1088	dTDP-glucose 4,6-dehydratase activity
NTM_RS01020	COG1960	acyl-CoA dehydrogenase activity
NTM_RS01035	COG2197	response regulator
NTM_RS01065	COG0563	adenylate kinase activity
NTM_RS01075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NTM_RS01080	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NTM_RS01085	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NTM_RS01090	COG0616	signal peptide processing
NTM_RS01100	COG0200	Binds to the 23S rRNA
NTM_RS01105	COG1841	ribosomal large subunit assembly
NTM_RS01110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NTM_RS01115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NTM_RS01120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NTM_RS01125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NTM_RS01130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NTM_RS01140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NTM_RS01145	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NTM_RS01150	COG0154	amidase activity
NTM_RS01155	COG3069	C4-dicarboxylate transmembrane transporter activity
NTM_RS01165	COG0405	Gamma-glutamyltransferase
NTM_RS01170	COG2146	nitrite reductase [NAD(P)H] activity
NTM_RS01175	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS01185	COG4638	Rieske (2fe-2S)
NTM_RS01210	COG3069	C4-dicarboxylate transmembrane transporter activity
NTM_RS01215	COG3619	membrane
NTM_RS01220	COG1595	DNA-templated transcription, initiation
NTM_RS01265	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NTM_RS01270	COG0255	Belongs to the universal ribosomal protein uL29 family
NTM_RS01275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NTM_RS01280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NTM_RS01285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NTM_RS01290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NTM_RS01295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NTM_RS01300	COG0089	rRNA binding
NTM_RS01305	COG0088	Forms part of the polypeptide exit tunnel
NTM_RS01310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NTM_RS01315	COG0051	transcription antitermination factor activity, RNA binding
NTM_RS01340	COG0477	Major facilitator Superfamily
NTM_RS01375	COG0535	radical SAM domain protein
NTM_RS01395	COG1595	DNA-templated transcription, initiation
NTM_RS01420	COG1522	sequence-specific DNA binding
NTM_RS01425	COG1834	amidinotransferase
NTM_RS01430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NTM_RS01440	COG2235	arginine
NTM_RS01460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NTM_RS01465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NTM_RS01470	COG0049	tRNA binding
NTM_RS01475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NTM_RS01515	COG1960	acyl-CoA dehydrogenase activity
NTM_RS01560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NTM_RS01565	COG0085	RNA polymerase activity
NTM_RS01580	COG0222	ribosome binding
NTM_RS01585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NTM_RS01640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NTM_RS01645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NTM_RS01650	COG0081	regulation of translation
NTM_RS01655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NTM_RS01665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NTM_RS01680	COG2030	dehydratase
NTM_RS01685	COG2030	dehydratase
NTM_RS01690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NTM_RS01705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NTM_RS01725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NTM_RS01735	COG2072	flavoprotein involved in K transport
NTM_RS01745	COG2144	transferase activity, transferring acyl groups
NTM_RS01760	COG0598	Magnesium transport protein CorA
NTM_RS01765	COG0446	pyridine nucleotide-disulphide oxidoreductase
NTM_RS01775	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
NTM_RS01775	COG0778	Nitroreductase
NTM_RS01780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NTM_RS01785	COG1074	ATP-dependent DNA helicase activity
NTM_RS01790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NTM_RS01810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NTM_RS01825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS01865	COG3706	GGDEF domain
NTM_RS01865	COG2203	Gaf domain
NTM_RS01865	COG5001	Diguanylate cyclase
NTM_RS01865	COG4251	negative regulation of phosphorylation
NTM_RS01870	COG0058	SHG alpha-glucan phosphorylase activity
NTM_RS01920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS01925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS01930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS01935	COG0747	negative chemotaxis
NTM_RS01960	COG2897	thiosulfate sulfurtransferase activity
NTM_RS01980	COG1404	Belongs to the peptidase S8 family
NTM_RS02000	COG1335	isochorismatase
NTM_RS02015	COG1174	glycine betaine transport
NTM_RS02030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS02100	COG1120	ATPase activity
NTM_RS02105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NTM_RS02125	COG1309	transcriptional regulator
NTM_RS02130	COG0477	Major facilitator Superfamily
NTM_RS02135	COG2814	Major facilitator Superfamily
NTM_RS02145	COG0492	ferredoxin-NADP+ reductase activity
NTM_RS02155	COG0437	4 iron, 4 sulfur cluster binding
NTM_RS02160	COG3383	formate dehydrogenase (NAD+) activity
NTM_RS02160	COG0243	molybdopterin cofactor binding
NTM_RS02165	COG0243	molybdopterin cofactor binding
NTM_RS02165	COG3383	formate dehydrogenase (NAD+) activity
NTM_RS02175	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NTM_RS02180	COG3276	selenocysteine insertion sequence binding
NTM_RS02195	COG0709	Synthesizes selenophosphate from selenide and ATP
NTM_RS02205	COG0129	dihydroxy-acid dehydratase activity
NTM_RS02210	COG2258	MOSC domain
NTM_RS02225	COG1309	transcriptional regulator
NTM_RS02230	COG5001	Diguanylate cyclase
NTM_RS02230	COG5002	protein histidine kinase activity
NTM_RS02230	COG3447	MASE1 domain protein
NTM_RS02235	COG1764	response to oxidative stress
NTM_RS02240	COG1846	Transcriptional regulator
NTM_RS02265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS02280	COG2720	vancomycin resistance protein
NTM_RS02305	COG1752	Esterase of the alpha-beta hydrolase superfamily
NTM_RS02315	COG0653	protein targeting
NTM_RS02325	COG2002	toxin-antitoxin pair type II binding
NTM_RS02350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NTM_RS02395	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NTM_RS02430	COG1201	RNA secondary structure unwinding
NTM_RS02440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NTM_RS02455	COG1061	Type III restriction enzyme res subunit
NTM_RS02460	COG0514	ATP-dependent DNA helicase (RecQ)
NTM_RS02480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NTM_RS02520	COG0477	Major facilitator Superfamily
NTM_RS02525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NTM_RS02555	COG0297	glycogen (starch) synthase activity
NTM_RS02560	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS02605	COG1278	Cold shock
NTM_RS02615	COG2409	Drug exporters of the RND superfamily
NTM_RS02650	COG1733	regulation of RNA biosynthetic process
NTM_RS02660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NTM_RS02675	COG4221	oxidoreductase activity
NTM_RS02705	COG1666	GTP binding
NTM_RS02720	COG1176	ABC-type spermidine putrescine transport system, permease component I
NTM_RS02725	COG1177	transmembrane transport
NTM_RS02735	COG0006	proline dipeptidase activity
NTM_RS02755	COG0501	Belongs to the peptidase M48B family
NTM_RS02760	COG0142	geranyltranstransferase activity
NTM_RS02765	COG0644	oxidoreductase
NTM_RS02790	COG2226	methyltransferase
NTM_RS02795	COG4221	oxidoreductase activity
NTM_RS02815	COG1845	cytochrome c oxidase, subunit III
NTM_RS02835	COG0438	transferase activity, transferring glycosyl groups
NTM_RS02850	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NTM_RS02870	COG4977	sequence-specific DNA binding
NTM_RS02875	COG4948	Mandelate Racemase Muconate Lactonizing
NTM_RS02950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS02970	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS02990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NTM_RS03015	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NTM_RS03065	COG0745	RESPONSE REGULATOR receiver
NTM_RS03070	COG2202	Pas domain
NTM_RS03070	COG2205	protein histidine kinase activity
NTM_RS03075	COG2070	2-Nitropropane dioxygenase
NTM_RS03080	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NTM_RS03095	COG0542	response to heat
NTM_RS03105	COG0714	Associated with various cellular activities
NTM_RS03150	COG2894	cell division
NTM_RS03155	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NTM_RS03165	COG0785	Cytochrome C biogenesis protein
NTM_RS03175	COG0406	alpha-ribazole phosphatase activity
NTM_RS03180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NTM_RS03250	COG0181	hydroxymethylbilane synthase activity
NTM_RS03255	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NTM_RS03270	COG2030	dehydratase
NTM_RS03325	COG0745	RESPONSE REGULATOR receiver
NTM_RS03330	COG5002	protein histidine kinase activity
NTM_RS03345	COG0438	transferase activity, transferring glycosyl groups
NTM_RS03375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NTM_RS03395	COG0010	Belongs to the arginase family
NTM_RS03410	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NTM_RS03435	COG2733	membrane
NTM_RS03445	COG2326	polyphosphate kinase activity
NTM_RS03485	COG3706	GGDEF domain
NTM_RS03500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NTM_RS03505	COG0444	Belongs to the ABC transporter superfamily
NTM_RS03510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NTM_RS03515	COG4168	peptide transport system, permease
NTM_RS03520	COG0747	negative chemotaxis
NTM_RS03550	COG1063	alcohol dehydrogenase
NTM_RS03560	COG1505	serine-type exopeptidase activity
NTM_RS03575	COG0586	Pfam SNARE associated Golgi protein
NTM_RS03585	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS03610	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NTM_RS03620	COG0300	oxidoreductase activity
NTM_RS03630	COG0604	alcohol dehydrogenase
NTM_RS03635	COG0477	Major facilitator Superfamily
NTM_RS03645	COG0459	protein refolding
NTM_RS03675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NTM_RS03685	COG0647	UMP catabolic process
NTM_RS03700	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS03710	COG0688	phosphatidylethanolamine metabolic process
NTM_RS03720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NTM_RS03730	COG3263	regulation of cellular component size
NTM_RS03740	COG2111	Na H antiporter
NTM_RS03740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NTM_RS03760	COG2212	antiporter activity
NTM_RS03770	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NTM_RS03795	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NTM_RS03815	COG0242	peptide deformylase activity
NTM_RS03845	COG2814	Major facilitator Superfamily
NTM_RS03850	COG0351	phosphomethylpyrimidine kinase
NTM_RS03875	COG1309	transcriptional regulator
NTM_RS03885	COG2233	PERMEase
NTM_RS03895	COG2234	aminopeptidase activity
NTM_RS03900	COG2234	aminopeptidase activity
NTM_RS03915	COG1131	(ABC) transporter
NTM_RS03920	COG2022	thiamine diphosphate biosynthetic process
NTM_RS03930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NTM_RS03935	COG0352	thiamine-phosphate diphosphorylase activity
NTM_RS03950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NTM_RS03955	COG0515	serine threonine protein kinase
NTM_RS03965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NTM_RS04000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS04005	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NTM_RS04015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS04020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS04040	COG4221	oxidoreductase activity
NTM_RS04065	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NTM_RS04080	COG2409	Drug exporters of the RND superfamily
NTM_RS04085	COG2124	cytochrome p450
NTM_RS04105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NTM_RS04120	COG1994	Peptidase M50
NTM_RS04150	COG0586	Pfam SNARE associated Golgi protein
NTM_RS04155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NTM_RS04155	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NTM_RS04170	COG0477	Major facilitator Superfamily
NTM_RS04175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NTM_RS04185	COG0300	oxidoreductase activity
NTM_RS04195	COG0542	response to heat
NTM_RS04255	COG0789	Transcriptional regulator
NTM_RS04260	COG0484	heat shock protein binding
NTM_RS04265	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NTM_RS04270	COG0443	Heat shock 70 kDa protein
NTM_RS04285	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NTM_RS04345	COG0247	lactate metabolic process
NTM_RS04345	COG2181	nitrate reductase activity
NTM_RS04365	COG2080	2 iron, 2 sulfur cluster binding
NTM_RS04370	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NTM_RS04375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NTM_RS04390	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS04415	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS04420	COG1304	FMN binding
NTM_RS04425	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS04430	COG2186	Transcriptional regulator
NTM_RS04465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NTM_RS04475	COG0717	Belongs to the dCTP deaminase family
NTM_RS04520	COG0477	Major facilitator Superfamily
NTM_RS04535	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS04545	COG0039	L-malate dehydrogenase activity
NTM_RS04550	COG0747	negative chemotaxis
NTM_RS04560	COG0601	transmembrane transport
NTM_RS04565	COG0444	Belongs to the ABC transporter superfamily
NTM_RS04570	COG4608	Belongs to the ABC transporter superfamily
NTM_RS04590	COG1597	lipid kinase activity
NTM_RS04610	COG1403	HNH endonuclease
NTM_RS04615	COG3119	arylsulfatase activity
NTM_RS04620	COG4424	Sulfotransferase
NTM_RS04625	COG4106	trans-aconitate 2-methyltransferase activity
NTM_RS04640	COG1404	Belongs to the peptidase S8 family
NTM_RS04655	COG4842	Belongs to the WXG100 family
NTM_RS04675	COG1674	ftsk spoiiie
NTM_RS04680	COG3266	domain, Protein
NTM_RS04685	COG0464	growth
NTM_RS04700	COG0346	lactoylglutathione lyase activity
NTM_RS04715	COG1960	acyl-CoA dehydrogenase activity
NTM_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS04745	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS04760	COG1960	acyl-CoA dehydrogenase activity
NTM_RS04765	COG1960	acyl-CoA dehydrogenase activity
NTM_RS04775	COG2252	PERMEase
NTM_RS04795	COG1082	Xylose isomerase domain protein TIM barrel
NTM_RS04800	COG0673	inositol 2-dehydrogenase activity
NTM_RS04810	COG2814	Major facilitator Superfamily
NTM_RS04835	COG0778	Nitroreductase
NTM_RS04870	COG1492	cobalamin metabolic process
NTM_RS04935	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
NTM_RS04945	COG1733	regulation of RNA biosynthetic process
NTM_RS04985	COG2855	membrane
NTM_RS05005	COG1984	allophanate hydrolase subunit 2
NTM_RS05030	COG2146	nitrite reductase [NAD(P)H] activity
NTM_RS05035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NTM_RS05035	COG2146	nitrite reductase [NAD(P)H] activity
NTM_RS05055	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NTM_RS05070	COG1053	succinate dehydrogenase
NTM_RS05085	COG1522	sequence-specific DNA binding
NTM_RS05095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NTM_RS05115	COG5651	PPE family
NTM_RS05120	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS05140	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NTM_RS05150	COG1960	acyl-CoA dehydrogenase activity
NTM_RS05155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS05165	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS05170	COG2030	dehydratase
NTM_RS05185	COG1472	Belongs to the glycosyl hydrolase 3 family
NTM_RS05190	COG0589	response to stress
NTM_RS05200	COG4981	capsule polysaccharide biosynthetic process
NTM_RS05245	COG0500	methyltransferase
NTM_RS05260	COG1960	acyl-CoA dehydrogenase activity
NTM_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS05290	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS05320	COG1960	acyl-CoA dehydrogenase activity
NTM_RS05350	COG2188	Transcriptional regulator
NTM_RS05355	COG1024	Enoyl-CoA hydratase
NTM_RS05365	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
NTM_RS05370	COG1309	transcriptional regulator
NTM_RS05375	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NTM_RS05390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NTM_RS05400	COG2409	Drug exporters of the RND superfamily
NTM_RS05445	COG2409	Drug exporters of the RND superfamily
NTM_RS05460	COG2409	Drug exporters of the RND superfamily
NTM_RS05480	COG3590	peptidase
NTM_RS05485	COG3011	Protein conserved in bacteria
NTM_RS05500	COG0714	Associated with various cellular activities
NTM_RS05515	COG1376	ErfK ybiS ycfS ynhG family protein
NTM_RS05535	COG1937	Protein conserved in bacteria
NTM_RS05560	COG0477	Major facilitator Superfamily
NTM_RS05565	COG0583	DNA-binding transcription factor activity
NTM_RS05595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NTM_RS05605	COG0574	Belongs to the PEP-utilizing enzyme family
NTM_RS05605	COG3848	Pyruvate phosphate dikinase
NTM_RS05615	COG1595	DNA-templated transcription, initiation
NTM_RS05625	COG0187	DNA topoisomerase II activity
NTM_RS05630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NTM_RS05640	COG1072	(Pantothenic acid kinase))
NTM_RS05645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NTM_RS05680	COG1024	Enoyl-CoA hydratase
NTM_RS05695	COG1960	acyl-CoA dehydrogenase activity
NTM_RS05715	COG1960	acyl-CoA dehydrogenase activity
NTM_RS05750	COG1960	acyl-CoA dehydrogenase activity
NTM_RS05755	COG1960	acyl-CoA dehydrogenase activity
NTM_RS05765	COG1960	acyl-CoA dehydrogenase activity
NTM_RS05795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS05800	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS05810	COG1960	acyl-CoA dehydrogenase activity
NTM_RS05825	COG1960	acyl-CoA dehydrogenase activity
NTM_RS05835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NTM_RS05840	COG1309	transcriptional regulator
NTM_RS05855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS05860	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS05890	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS05940	COG1309	transcriptional regulator
NTM_RS05945	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS05955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NTM_RS05960	COG0028	Belongs to the TPP enzyme family
NTM_RS05975	COG1522	sequence-specific DNA binding
NTM_RS06010	COG0702	epimerase
NTM_RS06025	COG0569	domain protein
NTM_RS06025	COG2985	domain, Protein
NTM_RS06030	COG4122	O-methyltransferase activity
NTM_RS06055	COG2267	carboxylic ester hydrolase activity
NTM_RS06130	COG3619	membrane
NTM_RS06160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NTM_RS06185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS06190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS06210	COG0668	transmembrane transport
NTM_RS06215	COG1801	Protein of unknown function DUF72
NTM_RS06220	COG1309	transcriptional regulator
NTM_RS06235	COG4521	taurine ABC transporter
NTM_RS06240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NTM_RS06250	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NTM_RS06255	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NTM_RS06260	COG4585	Histidine kinase
NTM_RS06275	COG0723	plastoquinol--plastocyanin reductase activity
NTM_RS06275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NTM_RS06280	COG1982	Orn Lys Arg decarboxylase major
NTM_RS06315	COG2130	NADP-dependent
NTM_RS06320	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS06325	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS06330	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NTM_RS06360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NTM_RS06365	COG1349	DNA-binding transcription factor activity
NTM_RS06370	COG1105	Belongs to the carbohydrate kinase PfkB family
NTM_RS06375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NTM_RS06375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NTM_RS06385	COG1404	Belongs to the peptidase S8 family
NTM_RS06450	COG4842	Belongs to the WXG100 family
NTM_RS06525	COG0024	Methionine aminopeptidase
NTM_RS06530	COG1673	EVE domain
NTM_RS06560	COG1309	transcriptional regulator
NTM_RS06570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NTM_RS06570	COG1116	anion transmembrane transporter activity
NTM_RS06575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NTM_RS06590	COG2084	Dehydrogenase
NTM_RS06600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NTM_RS06610	COG4977	sequence-specific DNA binding
NTM_RS06615	COG2814	Major facilitator Superfamily
NTM_RS06650	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS06655	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS06660	COG0531	amino acid
NTM_RS06670	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS06675	COG1879	ABC-type sugar transport system periplasmic component
NTM_RS06680	COG1172	Belongs to the binding-protein-dependent transport system permease family
NTM_RS06685	COG1129	ABC transporter
NTM_RS06690	COG0698	ribose 5-phosphate isomerase
NTM_RS06695	COG2376	Dihydroxyacetone kinase
NTM_RS06700	COG3842	ATPase activity
NTM_RS06705	COG3842	ATPase activity
NTM_RS06720	COG1653	transport
NTM_RS06725	COG1063	alcohol dehydrogenase
NTM_RS06735	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS06740	COG1070	Carbohydrate kinase
NTM_RS06755	COG1716	ATPase activity
NTM_RS06760	COG1716	ATPase activity
NTM_RS06775	COG0768	penicillin binding
NTM_RS06785	COG0515	serine threonine protein kinase
NTM_RS06785	COG2815	serine threonine protein kinase
NTM_RS06820	COG1760	l-serine dehydratase
NTM_RS06830	COG2066	Belongs to the glutaminase family
NTM_RS06860	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NTM_RS06865	COG0187	DNA topoisomerase II activity
NTM_RS06870	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NTM_RS06875	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NTM_RS06880	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NTM_RS06885	COG0592	DNA-directed DNA polymerase activity
NTM_RS06890	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NTM_RS06895	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NTM_RS06900	COG0594	ribonuclease P activity
NTM_RS06910	COG0706	membrane insertase activity
NTM_RS06920	COG0357	Ribosomal RNA small subunit methyltransferase G
NTM_RS06925	COG1192	Involved in chromosome partitioning
NTM_RS06940	COG0860	N-Acetylmuramoyl-L-alanine amidase
NTM_RS06940	COG3409	Peptidoglycan-binding domain 1 protein
NTM_RS06960	COG1595	DNA-templated transcription, initiation
NTM_RS07000	COG1678	Uncharacterized ACR, COG1678
NTM_RS07015	COG0495	leucyl-tRNA aminoacylation
NTM_RS07025	COG4221	oxidoreductase activity
NTM_RS07040	COG1126	abc transporter atp-binding protein
NTM_RS07045	COG0765	amino acid transport
NTM_RS07055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS07085	COG1260	myo-inositol-1-phosphate synthase
NTM_RS07105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NTM_RS07115	COG0360	Binds together with S18 to 16S ribosomal RNA
NTM_RS07125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NTM_RS07130	COG0359	binds to the 23S rRNA
NTM_RS07160	COG0300	oxidoreductase activity
NTM_RS07195	COG2079	MmgE PrpD family protein
NTM_RS07225	COG0596	Alpha beta hydrolase
NTM_RS07235	COG0596	Alpha beta hydrolase
NTM_RS07255	COG2197	response regulator
NTM_RS07265	COG1620	l-lactate permease
NTM_RS07270	COG0277	FAD linked oxidase domain protein
NTM_RS07285	COG2610	gluconate transmembrane transporter activity
NTM_RS07290	COG3265	gluconokinase activity
NTM_RS07310	COG2124	cytochrome p450
NTM_RS07315	COG2072	flavoprotein involved in K transport
NTM_RS07340	COG1250	3-hydroxyacyl-CoA dehydrogenase
NTM_RS07355	COG2376	Dihydroxyacetone kinase
NTM_RS07360	COG0698	ribose 5-phosphate isomerase
NTM_RS07365	COG0149	triose-phosphate isomerase activity
NTM_RS07400	COG1403	HNH endonuclease
NTM_RS07410	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NTM_RS07420	COG3757	hydrolase, family 25
NTM_RS07435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NTM_RS07450	COG4585	Histidine kinase
NTM_RS07460	COG2085	NADP oxidoreductase coenzyme F420-dependent
NTM_RS07470	COG4721	ABC-type cobalt transport system, permease component
NTM_RS07475	COG1122	ATPase activity
NTM_RS07490	COG2814	Major facilitator Superfamily
NTM_RS07530	COG1937	Protein conserved in bacteria
NTM_RS07540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NTM_RS07545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NTM_RS07555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NTM_RS07565	COG0069	glutamate synthase activity
NTM_RS07570	COG1309	transcriptional regulator
NTM_RS07575	COG2124	cytochrome p450
NTM_RS07585	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS07620	COG0277	FAD linked oxidase domain protein
NTM_RS07635	COG2860	membrane
NTM_RS07650	COG2030	dehydratase
NTM_RS07655	COG0488	(ABC) transporter
NTM_RS07675	COG3300	MHYT domain
NTM_RS07675	COG5001	Diguanylate cyclase
NTM_RS07680	COG0784	Response regulator, receiver
NTM_RS07680	COG5002	protein histidine kinase activity
NTM_RS07680	COG2198	Histidine kinase
NTM_RS07685	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NTM_RS07690	COG2201	protein-glutamate methylesterase activity
NTM_RS07705	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NTM_RS07710	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NTM_RS07720	COG0583	DNA-binding transcription factor activity
NTM_RS07735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NTM_RS07750	COG2233	PERMEase
NTM_RS07755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NTM_RS07760	COG1335	isochorismatase
NTM_RS07810	COG3795	YCII-related domain
NTM_RS07815	COG4941	Belongs to the sigma-70 factor family
NTM_RS07825	COG0154	amidase activity
NTM_RS07855	COG1946	Acyl-CoA thioesterase
NTM_RS07860	COG1408	metallophosphoesterase
NTM_RS07865	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS07875	COG1454	alcohol dehydrogenase
NTM_RS07880	COG0824	Thioesterase
NTM_RS07905	COG2770	Histidine kinase
NTM_RS07905	COG2208	phosphoserine phosphatase activity
NTM_RS07915	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NTM_RS07935	COG0693	protein deglycase activity
NTM_RS07955	COG2890	protein-(glutamine-N5) methyltransferase activity
NTM_RS07980	COG0494	nUDIX hydrolase
NTM_RS07995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS08000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS08025	COG0028	Belongs to the TPP enzyme family
NTM_RS08030	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS08050	COG0523	cobalamin synthesis protein
NTM_RS08090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NTM_RS08095	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NTM_RS08115	COG1643	Atp-dependent helicase
NTM_RS08120	COG4221	oxidoreductase activity
NTM_RS08130	COG1063	alcohol dehydrogenase
NTM_RS08145	COG3467	pyridoxamine 5'-phosphate
NTM_RS08190	COG3158	transport of potassium into the cell
NTM_RS08200	COG0477	Major facilitator Superfamily
NTM_RS08210	COG1595	DNA-templated transcription, initiation
NTM_RS08240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NTM_RS08255	COG3281	Trehalose synthase
NTM_RS08260	COG0842	Transport permease protein
NTM_RS08265	COG1131	(ABC) transporter
NTM_RS08280	COG1335	isochorismatase
NTM_RS08285	COG3707	response regulator
NTM_RS08305	COG1960	acyl-CoA dehydrogenase activity
NTM_RS08310	COG2223	nitrite transmembrane transporter activity
NTM_RS08320	COG3467	pyridoxamine 5'-phosphate
NTM_RS08325	COG0438	transferase activity, transferring glycosyl groups
NTM_RS08330	COG2226	methyltransferase
NTM_RS08360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NTM_RS08380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NTM_RS08395	COG0783	Belongs to the Dps family
NTM_RS08405	COG0067	glutamate synthase
NTM_RS08405	COG0070	glutamate synthase
NTM_RS08405	COG0069	glutamate synthase activity
NTM_RS08435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NTM_RS08435	COG1796	DNA polymerase
NTM_RS08440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NTM_RS08450	COG2072	flavoprotein involved in K transport
NTM_RS08455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NTM_RS08515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NTM_RS08515	COG0425	Belongs to the sulfur carrier protein TusA family
NTM_RS08530	COG1528	Iron-storage protein
NTM_RS08535	COG1316	TRANSCRIPTIONal
NTM_RS08550	COG0077	Prephenate dehydratase
NTM_RS08575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NTM_RS08585	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NTM_RS08585	COG2146	nitrite reductase [NAD(P)H] activity
NTM_RS08590	COG0204	Acyl-transferase
NTM_RS08600	COG0561	phosphatase activity
NTM_RS08620	COG1216	Glycosyl transferase, family 2
NTM_RS08625	COG0671	phosphoesterase, PA-phosphatase related
NTM_RS08630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NTM_RS08635	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NTM_RS08640	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NTM_RS08670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NTM_RS08705	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS08710	COG0277	FAD linked oxidase domain protein
NTM_RS08730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NTM_RS08735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NTM_RS08750	COG1216	Glycosyl transferase, family 2
NTM_RS08785	COG0477	Major facilitator Superfamily
NTM_RS08800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NTM_RS08830	COG1733	regulation of RNA biosynthetic process
NTM_RS08845	COG2015	COG2015, Alkyl sulfatase and related hydrolases
NTM_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS08865	COG1305	Transglutaminase-like
NTM_RS08885	COG1174	glycine betaine transport
NTM_RS08900	COG0287	Prephenate dehydrogenase
NTM_RS08910	COG0590	tRNA wobble adenosine to inosine editing
NTM_RS08930	COG1063	alcohol dehydrogenase
NTM_RS08935	COG2213	PTS system mannitol-specific
NTM_RS08935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NTM_RS08940	COG1349	DNA-binding transcription factor activity
NTM_RS08985	COG0343	queuine tRNA-ribosyltransferase activity
NTM_RS09000	COG0300	oxidoreductase activity
NTM_RS09005	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS09015	COG1126	abc transporter atp-binding protein
NTM_RS09020	COG0765	amino acid transport
NTM_RS09025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NTM_RS09030	COG2188	Transcriptional regulator
NTM_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS09070	COG1454	alcohol dehydrogenase
NTM_RS09070	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS09115	COG1793	dna ligase
NTM_RS09120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NTM_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS09145	COG2124	cytochrome p450
NTM_RS09150	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS09160	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
NTM_RS09160	COG0778	Nitroreductase
NTM_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS09200	COG0346	lactoylglutathione lyase activity
NTM_RS09205	COG1982	Orn Lys Arg decarboxylase major
NTM_RS09210	COG1793	dna ligase
NTM_RS09235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NTM_RS09255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NTM_RS09270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NTM_RS09285	COG0860	N-Acetylmuramoyl-L-alanine amidase
NTM_RS09295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NTM_RS09305	COG1492	cobalamin metabolic process
NTM_RS09310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NTM_RS09325	COG2226	methyltransferase
NTM_RS09330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NTM_RS09345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NTM_RS09350	COG0069	glutamate synthase activity
NTM_RS09355	COG2218	PFAM glutamate synthase alpha subunit domain protein
NTM_RS09360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NTM_RS09415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NTM_RS09420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NTM_RS09425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NTM_RS09445	COG3572	ergothioneine biosynthetic process
NTM_RS09450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NTM_RS09455	COG0121	glutamine amidotransferase
NTM_RS09460	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NTM_RS09465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NTM_RS09475	COG1301	dicarboxylic acid transport
NTM_RS09490	COG2226	methyltransferase
NTM_RS09495	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NTM_RS09500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NTM_RS09505	COG0667	Aldo Keto reductase
NTM_RS09520	COG1953	Uracil, thiamine, allantoin
NTM_RS09530	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
NTM_RS09555	COG0714	Associated with various cellular activities
NTM_RS09580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS09605	COG0583	DNA-binding transcription factor activity
NTM_RS09610	COG0183	Belongs to the thiolase family
NTM_RS09615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NTM_RS09645	COG4638	Rieske (2fe-2S)
NTM_RS09650	COG0583	DNA-binding transcription factor activity
NTM_RS09655	COG4948	Mandelate Racemase Muconate Lactonizing
NTM_RS09660	COG3485	protocatechuate 3,4-dioxygenase
NTM_RS09665	COG4829	muconolactone delta-isomerase
NTM_RS09685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NTM_RS09690	COG1408	metallophosphoesterase
NTM_RS09725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NTM_RS09745	COG3118	belongs to the thioredoxin family
NTM_RS09750	COG0494	nUDIX hydrolase
NTM_RS09775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NTM_RS09820	COG0515	serine threonine protein kinase
NTM_RS09830	COG1111	helicase
NTM_RS09830	COG1205	dead DEAH box helicase
NTM_RS09835	COG1278	Cold shock
NTM_RS09845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NTM_RS09845	COG1754	DNA topoisomerase type I activity
NTM_RS09855	COG0470	DNA polymerase III
NTM_RS09865	COG1376	ErfK ybiS ycfS ynhG family protein
NTM_RS09880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NTM_RS09910	COG4266	Belongs to the allantoicase family
NTM_RS09925	COG2027	D-alanyl-D-alanine carboxypeptidase
NTM_RS09935	COG0037	tRNA processing
NTM_RS09945	COG0243	molybdopterin cofactor binding
NTM_RS09955	COG2267	carboxylic ester hydrolase activity
NTM_RS09965	COG0302	gtp cyclohydrolase
NTM_RS09970	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NTM_RS10000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NTM_RS10005	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NTM_RS10015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NTM_RS10025	COG0542	response to heat
NTM_RS10070	COG1194	a g-specific adenine glycosylase
NTM_RS10075	COG0288	reversible hydration of carbon dioxide
NTM_RS10085	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NTM_RS10090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NTM_RS10100	COG1329	Transcriptional regulator
NTM_RS10105	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NTM_RS10110	COG0215	cysteine-tRNA ligase activity
NTM_RS10115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NTM_RS10120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NTM_RS10135	COG0640	Transcriptional regulator
NTM_RS10140	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NTM_RS10150	COG3706	GGDEF domain
NTM_RS10160	COG1121	(ABC) transporter
NTM_RS10165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NTM_RS10170	COG1609	Transcriptional regulator
NTM_RS10175	COG1877	trehalose-phosphatase activity
NTM_RS10175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NTM_RS10180	COG1309	transcriptional regulator
NTM_RS10185	COG1960	acyl-CoA dehydrogenase activity
NTM_RS10200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NTM_RS10235	COG0583	DNA-binding transcription factor activity
NTM_RS10245	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS10250	COG1070	Carbohydrate kinase
NTM_RS10255	COG1940	carbohydrate kinase activity
NTM_RS10265	COG4213	ABC transporter substrate-binding protein
NTM_RS10275	COG4214	carbohydrate transport
NTM_RS10285	COG0477	Major facilitator Superfamily
NTM_RS10290	COG0436	Aminotransferase
NTM_RS10295	COG1960	acyl-CoA dehydrogenase activity
NTM_RS10300	COG1960	acyl-CoA dehydrogenase activity
NTM_RS10305	COG1960	acyl-CoA dehydrogenase activity
NTM_RS10310	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS10315	COG1960	acyl-CoA dehydrogenase activity
NTM_RS10320	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS10325	COG2244	polysaccharide biosynthetic process
NTM_RS10350	COG1309	transcriptional regulator
NTM_RS10355	COG0183	Belongs to the thiolase family
NTM_RS10385	COG1024	Enoyl-CoA hydratase
NTM_RS10390	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS10410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NTM_RS10440	COG0183	Belongs to the thiolase family
NTM_RS10445	COG2124	cytochrome p450
NTM_RS10450	COG1960	acyl-CoA dehydrogenase activity
NTM_RS10455	COG1960	acyl-CoA dehydrogenase activity
NTM_RS10495	COG2030	dehydratase
NTM_RS10500	COG1053	succinate dehydrogenase
NTM_RS10505	COG3971	2-oxopent-4-enoate hydratase activity
NTM_RS10510	COG4569	acetaldehyde dehydrogenase (acetylating) activity
NTM_RS10525	COG0514	ATP-dependent DNA helicase (RecQ)
NTM_RS10550	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS10565	COG4638	Rieske (2fe-2S)
NTM_RS10575	COG1309	transcriptional regulator
NTM_RS10580	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NTM_RS10595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS10605	COG2124	cytochrome p450
NTM_RS10610	COG1024	Enoyl-CoA hydratase
NTM_RS10620	COG2070	2-Nitropropane dioxygenase
NTM_RS10625	COG0028	Belongs to the TPP enzyme family
NTM_RS10640	COG1053	succinate dehydrogenase
NTM_RS10645	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS10650	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS10655	COG1960	acyl-CoA dehydrogenase activity
NTM_RS10660	COG1960	acyl-CoA dehydrogenase activity
NTM_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS10675	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS10680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS10705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NTM_RS10735	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NTM_RS10740	COG1024	Enoyl-CoA hydratase
NTM_RS10750	COG2084	Dehydrogenase
NTM_RS10795	COG0679	Auxin Efflux Carrier
NTM_RS10820	COG0745	RESPONSE REGULATOR receiver
NTM_RS10840	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS10845	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS10850	COG2124	cytochrome p450
NTM_RS10860	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS10895	COG2124	cytochrome p450
NTM_RS10900	COG4221	oxidoreductase activity
NTM_RS10950	COG1309	transcriptional regulator
NTM_RS10955	COG2124	cytochrome p450
NTM_RS10975	COG0531	amino acid
NTM_RS10985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NTM_RS11000	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NTM_RS11015	COG0386	Belongs to the glutathione peroxidase family
NTM_RS11040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NTM_RS11055	COG2837	iron assimilation
NTM_RS11060	COG1362	aminopeptidase activity
NTM_RS11070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NTM_RS11100	COG0702	epimerase
NTM_RS11105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NTM_RS11135	COG1024	Enoyl-CoA hydratase
NTM_RS11145	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS11170	COG1309	transcriptional regulator
NTM_RS11175	COG1960	acyl-CoA dehydrogenase activity
NTM_RS11190	COG0406	alpha-ribazole phosphatase activity
NTM_RS11195	COG1960	acyl-CoA dehydrogenase activity
NTM_RS11200	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS11205	COG1250	3-hydroxyacyl-CoA dehydrogenase
NTM_RS11205	COG1024	Enoyl-CoA hydratase
NTM_RS11210	COG0183	Belongs to the thiolase family
NTM_RS11215	COG2072	flavoprotein involved in K transport
NTM_RS11235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS11240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS11265	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NTM_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS11305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NTM_RS11315	COG2030	dehydratase
NTM_RS11320	COG2030	dehydratase
NTM_RS11330	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS11340	COG4044	May play a role in the intracellular transport of hydrophobic ligands
NTM_RS11355	COG2897	thiosulfate sulfurtransferase activity
NTM_RS11375	COG0745	RESPONSE REGULATOR receiver
NTM_RS11380	COG0456	acetyltransferase
NTM_RS11395	COG0581	inorganic phosphate transmembrane transporter activity
NTM_RS11400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NTM_RS11410	COG1316	TRANSCRIPTIONal
NTM_RS11440	COG0515	serine threonine protein kinase
NTM_RS11470	COG1605	Chorismate mutase
NTM_RS11530	COG0829	nickel cation binding
NTM_RS11535	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NTM_RS11540	COG0804	urea catabolic process
NTM_RS11545	COG0832	Belongs to the urease beta subunit family
NTM_RS11545	COG0831	urea catabolic process
NTM_RS11555	COG2197	response regulator
NTM_RS11570	COG1902	pentaerythritol trinitrate reductase activity
NTM_RS11580	COG0183	Belongs to the thiolase family
NTM_RS11595	COG4977	sequence-specific DNA binding
NTM_RS11615	COG1061	Type III restriction enzyme res subunit
NTM_RS11640	COG0521	Mo-molybdopterin cofactor biosynthetic process
NTM_RS11670	COG1278	Cold shock
NTM_RS11680	COG0435	Glutathione S-transferase
NTM_RS11690	COG2814	Major facilitator Superfamily
NTM_RS11715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NTM_RS11730	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NTM_RS11750	COG2723	6-phospho-beta-galactosidase activity
NTM_RS11770	COG0259	pyridoxamine-phosphate oxidase activity
NTM_RS11775	COG1309	transcriptional regulator
NTM_RS11835	COG0545	Peptidyl-prolyl cis-trans isomerase
NTM_RS11855	COG1132	(ABC) transporter
NTM_RS11860	COG1132	(ABC) transporter
NTM_RS11865	COG1132	(ABC) transporter
NTM_RS11870	COG0596	Alpha beta hydrolase
NTM_RS11890	COG1511	domain protein
NTM_RS11920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NTM_RS11950	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NTM_RS11970	COG0714	Associated with various cellular activities
NTM_RS12000	COG3300	MHYT domain
NTM_RS12000	COG5001	Diguanylate cyclase
NTM_RS12005	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS12010	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS12015	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS12025	COG3386	PFAM SMP-30 Gluconolaconase
NTM_RS12030	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS12040	COG2072	flavoprotein involved in K transport
NTM_RS12045	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS12050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS12055	COG1960	acyl-CoA dehydrogenase activity
NTM_RS12065	COG1960	acyl-CoA dehydrogenase activity
NTM_RS12070	COG1960	acyl-CoA dehydrogenase activity
NTM_RS12100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NTM_RS12105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NTM_RS12145	COG0183	Belongs to the thiolase family
NTM_RS12205	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NTM_RS12210	COG5343	regulation of RNA biosynthetic process
NTM_RS12215	COG1595	DNA-templated transcription, initiation
NTM_RS12270	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NTM_RS12280	COG1793	dna ligase
NTM_RS12280	COG3285	dna ligase
NTM_RS12300	COG0328	RNA-DNA hybrid ribonuclease activity
NTM_RS12325	COG2814	Major facilitator Superfamily
NTM_RS12335	COG1940	carbohydrate kinase activity
NTM_RS12335	COG1846	Transcriptional regulator
NTM_RS12340	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NTM_RS12350	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
NTM_RS12395	COG1950	PFAM Membrane protein of
NTM_RS12400	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NTM_RS12420	COG0166	Belongs to the GPI family
NTM_RS12430	COG2755	lipolytic protein G-D-S-L family
NTM_RS12430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NTM_RS12435	COG1605	Chorismate mutase
NTM_RS12450	COG0739	heme binding
NTM_RS12455	COG0045	succinate-CoA ligase (ADP-forming) activity
NTM_RS12515	COG2188	Transcriptional regulator
NTM_RS12550	COG3842	ATPase activity
NTM_RS12555	COG0179	Fumarylacetoacetate (FAA) hydrolase
NTM_RS12560	COG3384	dioxygenase
NTM_RS12575	COG1228	amidohydrolase
NTM_RS12580	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
NTM_RS12595	COG1024	Enoyl-CoA hydratase
NTM_RS12610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NTM_RS12615	COG1960	acyl-CoA dehydrogenase activity
NTM_RS12630	COG0745	RESPONSE REGULATOR receiver
NTM_RS12635	COG2205	protein histidine kinase activity
NTM_RS12640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NTM_RS12645	COG0521	Mo-molybdopterin cofactor biosynthetic process
NTM_RS12645	COG0315	cyclic pyranopterin monophosphate synthase activity
NTM_RS12660	COG1970	mechanosensitive ion channel activity
NTM_RS12680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NTM_RS12685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NTM_RS12710	COG1403	HNH endonuclease
NTM_RS12725	COG1846	Transcriptional regulator
NTM_RS12750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NTM_RS12750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NTM_RS12755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NTM_RS12785	COG2235	arginine
NTM_RS12810	COG1595	DNA-templated transcription, initiation
NTM_RS12820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NTM_RS12830	COG0084	hydrolase, TatD family'
NTM_RS12835	COG3583	domain protein
NTM_RS12840	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NTM_RS12845	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NTM_RS12850	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS12885	COG0193	aminoacyl-tRNA hydrolase activity
NTM_RS12890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NTM_RS12905	COG1393	Belongs to the ArsC family
NTM_RS12915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NTM_RS12925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NTM_RS12940	COG1309	transcriptional regulator
NTM_RS12955	COG3956	TIGRFAM MazG family protein
NTM_RS12960	COG2837	iron assimilation
NTM_RS12965	COG2822	iron ion transport
NTM_RS12970	COG0672	)-iron permease
NTM_RS12980	COG4948	Mandelate Racemase Muconate Lactonizing
NTM_RS13025	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NTM_RS13030	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NTM_RS13035	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NTM_RS13065	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS13170	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NTM_RS13205	COG1363	Peptidase, m42
NTM_RS13225	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS13235	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS13250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NTM_RS13275	COG0038	chloride channel
NTM_RS13305	COG1595	DNA-templated transcription, initiation
NTM_RS13315	COG2119	membrane
NTM_RS13325	COG0477	Major facilitator Superfamily
NTM_RS13355	COG4565	transcriptional regulatory protein
NTM_RS13360	COG3290	protein histidine kinase activity
NTM_RS13365	COG1301	dicarboxylic acid transport
NTM_RS13370	COG0183	Belongs to the thiolase family
NTM_RS13395	COG0640	Transcriptional regulator
NTM_RS13425	COG1024	Enoyl-CoA hydratase
NTM_RS13440	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NTM_RS13445	COG0183	Belongs to the thiolase family
NTM_RS13450	COG2755	lipolytic protein G-D-S-L family
NTM_RS13455	COG0657	acetylesterase activity
NTM_RS13465	COG5473	translation initiation factor activity
NTM_RS13470	COG1714	RDD family
NTM_RS13485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NTM_RS13495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NTM_RS13505	COG1331	Highly conserved protein containing a thioredoxin domain
NTM_RS13510	COG3631	Ketosteroid isomerase-related protein
NTM_RS13540	COG0572	uridine kinase
NTM_RS13550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NTM_RS13560	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NTM_RS13600	COG4221	oxidoreductase activity
NTM_RS13605	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS13640	COG1570	exodeoxyribonuclease VII activity
NTM_RS13650	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NTM_RS13665	COG0012	GTP binding
NTM_RS13775	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS13780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS13805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NTM_RS13845	COG2186	Transcriptional regulator
NTM_RS13850	COG0183	Belongs to the thiolase family
NTM_RS13860	COG1960	acyl-CoA dehydrogenase activity
NTM_RS13865	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NTM_RS13880	COG0702	epimerase
NTM_RS13895	COG1024	Enoyl-CoA hydratase
NTM_RS13900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS13925	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NTM_RS13940	COG3467	pyridoxamine 5'-phosphate
NTM_RS13950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NTM_RS13960	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NTM_RS13970	COG3279	Response regulator of the LytR AlgR family
NTM_RS13990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NTM_RS14015	COG1051	belongs to the nudix hydrolase family
NTM_RS14020	COG2154	pterin-4-alpha-carbinolamine dehydratase
NTM_RS14030	COG3391	amine dehydrogenase activity
NTM_RS14030	COG5651	PPE family
NTM_RS14045	COG0747	negative chemotaxis
NTM_RS14050	COG3391	amine dehydrogenase activity
NTM_RS14055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NTM_RS14075	COG2353	YceI-like domain
NTM_RS14080	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NTM_RS14095	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS14110	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS14135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NTM_RS14150	COG1132	(ABC) transporter
NTM_RS14155	COG1611	Belongs to the LOG family
NTM_RS14160	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS14165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NTM_RS14170	COG0463	Glycosyl transferase, family 2
NTM_RS14180	COG0519	Catalyzes the synthesis of GMP from XMP
NTM_RS14190	COG0297	glycogen (starch) synthase activity
NTM_RS14195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NTM_RS14215	COG3559	Exporter of polyketide antibiotics
NTM_RS14220	COG1131	(ABC) transporter
NTM_RS14225	COG1309	transcriptional regulator
NTM_RS14230	COG4122	O-methyltransferase activity
NTM_RS14235	COG1595	DNA-templated transcription, initiation
NTM_RS14240	COG5662	AntiSigma factor
NTM_RS14245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NTM_RS14250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NTM_RS14270	COG2239	Acts as a magnesium transporter
NTM_RS14300	COG0598	Magnesium transport protein CorA
NTM_RS14325	COG0567	Dehydrogenase, E1 component
NTM_RS14325	COG0508	dehydrogenase complex catalyzes the overall conversion of
NTM_RS14335	COG2814	Major facilitator Superfamily
NTM_RS14350	COG0277	FAD linked oxidase domain protein
NTM_RS14390	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS14395	COG2197	response regulator
NTM_RS14400	COG4191	Histidine kinase
NTM_RS14405	COG0778	Nitroreductase
NTM_RS14440	COG0277	FAD linked oxidase domain protein
NTM_RS14455	COG1733	regulation of RNA biosynthetic process
NTM_RS14475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS14530	COG1490	D-aminoacyl-tRNA deacylase activity
NTM_RS14550	COG0243	molybdopterin cofactor binding
NTM_RS14590	COG2267	carboxylic ester hydrolase activity
NTM_RS14615	COG0745	RESPONSE REGULATOR receiver
NTM_RS14620	COG2205	protein histidine kinase activity
NTM_RS14630	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NTM_RS14640	COG0175	sulfate reduction
NTM_RS14650	COG1218	3'(2'),5'-bisphosphate nucleotidase
NTM_RS14685	COG2197	response regulator
NTM_RS14715	COG3590	peptidase
NTM_RS14720	COG1960	acyl-CoA dehydrogenase activity
NTM_RS14725	COG1960	acyl-CoA dehydrogenase activity
NTM_RS14735	COG0300	oxidoreductase activity
NTM_RS14770	COG0018	arginyl-trna synthetase
NTM_RS14775	COG0019	diaminopimelate decarboxylase activity
NTM_RS14780	COG0460	homoserine dehydrogenase
NTM_RS14785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NTM_RS14790	COG0083	homoserine kinase activity
NTM_RS14800	COG1309	transcriptional regulator
NTM_RS14805	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS14810	COG0254	rRNA binding
NTM_RS14815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NTM_RS14820	COG2890	protein-(glutamine-N5) methyltransferase activity
NTM_RS14830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NTM_RS14840	COG0356	it plays a direct role in the translocation of protons across the membrane
NTM_RS14845	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NTM_RS14850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NTM_RS14855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NTM_RS14855	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NTM_RS14860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NTM_RS14865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NTM_RS14870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NTM_RS14875	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NTM_RS14890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NTM_RS14930	COG4638	Rieske (2fe-2S)
NTM_RS14960	COG0583	DNA-binding transcription factor activity
NTM_RS14965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS14970	COG1960	acyl-CoA dehydrogenase activity
NTM_RS14975	COG1960	acyl-CoA dehydrogenase activity
NTM_RS14985	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NTM_RS14995	COG0346	lactoylglutathione lyase activity
NTM_RS15000	COG0183	Belongs to the thiolase family
NTM_RS15005	COG2409	Drug exporters of the RND superfamily
NTM_RS15020	COG0366	Alpha amylase catalytic
NTM_RS15025	COG0058	SHG alpha-glucan phosphorylase activity
NTM_RS15040	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NTM_RS15055	COG3191	aminopeptidase activity
NTM_RS15080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NTM_RS15085	COG1234	tRNA 3'-trailer cleavage
NTM_RS15090	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NTM_RS15110	COG1566	PFAM secretion protein HlyD family protein
NTM_RS15165	COG1309	transcriptional regulator
NTM_RS15175	COG1960	acyl-CoA dehydrogenase activity
NTM_RS15195	COG1309	transcriptional regulator
NTM_RS15205	COG0477	Major facilitator Superfamily
NTM_RS15210	COG4336	lyase activity
NTM_RS15225	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS15230	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS15235	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NTM_RS15235	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NTM_RS15240	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NTM_RS15245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS15250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS15255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NTM_RS15265	COG1960	acyl-CoA dehydrogenase activity
NTM_RS15270	COG1960	acyl-CoA dehydrogenase activity
NTM_RS15285	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS15285	COG3347	Dehydrogenase
NTM_RS15295	COG1309	transcriptional regulator
NTM_RS15300	COG1053	succinate dehydrogenase
NTM_RS15315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NTM_RS15320	COG3384	dioxygenase
NTM_RS15325	COG1053	succinate dehydrogenase
NTM_RS15380	COG0006	proline dipeptidase activity
NTM_RS15390	COG1024	Enoyl-CoA hydratase
NTM_RS15395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS15405	COG1403	HNH endonuclease
NTM_RS15435	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS15450	COG1024	Enoyl-CoA hydratase
NTM_RS15455	COG1960	acyl-CoA dehydrogenase activity
NTM_RS15460	COG1960	acyl-CoA dehydrogenase activity
NTM_RS15480	COG4638	Rieske (2fe-2S)
NTM_RS15500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS15505	COG1024	Enoyl-CoA hydratase
NTM_RS15510	COG0183	Belongs to the thiolase family
NTM_RS15515	COG1960	acyl-CoA dehydrogenase activity
NTM_RS15530	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS15530	COG3321	synthase
NTM_RS15530	COG0604	alcohol dehydrogenase
NTM_RS15540	COG1960	acyl-CoA dehydrogenase activity
NTM_RS15565	COG0714	Associated with various cellular activities
NTM_RS15605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NTM_RS15640	COG1141	Ferredoxin
NTM_RS15655	COG2124	cytochrome p450
NTM_RS15665	COG2124	cytochrome p450
NTM_RS15675	COG2084	Dehydrogenase
NTM_RS15730	COG1960	acyl-CoA dehydrogenase activity
NTM_RS15765	COG1141	Ferredoxin
NTM_RS15770	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS15785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS15800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS15805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS15830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NTM_RS15900	COG1024	Enoyl-CoA hydratase
NTM_RS15905	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS15915	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS15935	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NTM_RS15935	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NTM_RS15960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NTM_RS15995	COG1376	ErfK ybiS ycfS ynhG family protein
NTM_RS16010	COG0433	COG0433 Predicted ATPase
NTM_RS16015	COG0300	oxidoreductase activity
NTM_RS16045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NTM_RS16055	COG1960	acyl-CoA dehydrogenase activity
NTM_RS16090	COG2267	carboxylic ester hydrolase activity
NTM_RS16125	COG0629	single-stranded DNA binding
NTM_RS16135	COG2902	Dehydrogenase
NTM_RS16165	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NTM_RS16180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NTM_RS16215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NTM_RS16230	COG0544	peptidyl-prolyl cis-trans isomerase activity
NTM_RS16235	COG0740	serine-type endopeptidase activity
NTM_RS16255	COG2040	homocysteine
NTM_RS16260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NTM_RS16270	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NTM_RS16280	COG0583	DNA-binding transcription factor activity
NTM_RS16295	COG0673	inositol 2-dehydrogenase activity
NTM_RS16300	COG3962	Belongs to the TPP enzyme family
NTM_RS16305	COG3718	enzyme involved in inositol metabolism
NTM_RS16315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NTM_RS16320	COG2188	Transcriptional regulator
NTM_RS16345	COG1172	Belongs to the binding-protein-dependent transport system permease family
NTM_RS16355	COG4399	Belongs to the UPF0754 family
NTM_RS16380	COG0673	inositol 2-dehydrogenase activity
NTM_RS16395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NTM_RS16400	COG0674	pyruvate-flavodoxin oxidoreductase activity
NTM_RS16400	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NTM_RS16405	COG1013	pyruvate-flavodoxin oxidoreductase activity
NTM_RS16410	COG0746	molybdenum cofactor guanylyltransferase activity
NTM_RS16415	COG1388	LysM domain
NTM_RS16450	COG0004	ammonium transporteR
NTM_RS16455	COG0823	Involved in the tonB-independent uptake of proteins
NTM_RS16455	COG1506	peptidase
NTM_RS16460	COG3268	Saccharopine dehydrogenase
NTM_RS16470	COG0525	valine-tRNA ligase activity
NTM_RS16475	COG0285	dihydrofolate synthase activity
NTM_RS16485	COG0105	UTP biosynthetic process
NTM_RS16490	COG1530	ribonuclease E activity
NTM_RS16500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NTM_RS16505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NTM_RS16510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NTM_RS16545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NTM_RS16550	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NTM_RS16555	COG0542	response to heat
NTM_RS16575	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NTM_RS16580	COG0799	negative regulation of ribosome biogenesis
NTM_RS16585	COG0406	alpha-ribazole phosphatase activity
NTM_RS16590	COG2755	lipolytic protein G-D-S-L family
NTM_RS16605	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS16615	COG1960	acyl-CoA dehydrogenase activity
NTM_RS16625	COG1555	photosystem II stabilization
NTM_RS16625	COG1596	polysaccharide export
NTM_RS16640	COG0268	Binds directly to 16S ribosomal RNA
NTM_RS16645	COG2308	Evidence 4 Homologs of previously reported genes of
NTM_RS16655	COG1305	Transglutaminase-like
NTM_RS16660	COG1234	tRNA 3'-trailer cleavage
NTM_RS16695	COG0174	glutamine synthetase
NTM_RS16730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS16760	COG0747	negative chemotaxis
NTM_RS16765	COG0601	transmembrane transport
NTM_RS16770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NTM_RS16775	COG4172	Belongs to the ABC transporter superfamily
NTM_RS16780	COG4552	Acetyltransferase involved in intracellular survival and related
NTM_RS16785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS16790	COG1464	Belongs to the NlpA lipoprotein family
NTM_RS16795	COG2011	ABC-type metal ion transport system permease component
NTM_RS16800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NTM_RS16810	COG3387	PFAM Glycoside hydrolase 15-related
NTM_RS16830	COG4208	sulfate ABC transporter
NTM_RS16835	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NTM_RS16895	COG1021	2,3-dihydroxybenzoate-AMP ligase
NTM_RS16920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NTM_RS16920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NTM_RS16935	COG3251	PFAM MbtH domain protein
NTM_RS16950	COG1420	regulation of RNA biosynthetic process
NTM_RS16955	COG0484	heat shock protein binding
NTM_RS16980	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NTM_RS17020	COG1381	Involved in DNA repair and RecF pathway recombination
NTM_RS17050	COG0423	glycine-tRNA ligase activity
NTM_RS17065	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NTM_RS17070	COG0358	DNA primase activity
NTM_RS17105	COG2814	Major facilitator Superfamily
NTM_RS17190	COG0668	transmembrane transport
NTM_RS17195	COG3104	oligopeptide transport
NTM_RS17220	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NTM_RS17240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NTM_RS17245	COG1403	HNH endonuclease
NTM_RS17260	COG4172	Belongs to the ABC transporter superfamily
NTM_RS17270	COG0601	transmembrane transport
NTM_RS17275	COG0747	negative chemotaxis
NTM_RS17285	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NTM_RS17350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NTM_RS17355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NTM_RS17370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NTM_RS17395	COG2357	RelA SpoT domain protein
NTM_RS17460	COG0697	spore germination
NTM_RS17465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NTM_RS17520	COG3634	alkyl hydroperoxide reductase activity
NTM_RS17525	COG2813	Specifically methylates the guanine in position
NTM_RS17540	COG2207	Transcriptional regulator
NTM_RS17560	COG1024	Enoyl-CoA hydratase
NTM_RS17565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NTM_RS17585	COG0174	glutamine synthetase
NTM_RS17590	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NTM_RS17600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS17610	COG2197	response regulator
NTM_RS17620	COG2259	Doxx family
NTM_RS17625	COG0174	glutamine synthetase
NTM_RS17645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NTM_RS17650	COG0321	lipoyl(octanoyl) transferase activity
NTM_RS17680	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NTM_RS17685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NTM_RS17690	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NTM_RS17695	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NTM_RS17720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NTM_RS17750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NTM_RS17765	COG1845	cytochrome c oxidase, subunit III
NTM_RS17795	COG0438	transferase activity, transferring glycosyl groups
NTM_RS17800	COG1022	Amp-dependent synthetase and ligase
NTM_RS17815	COG0003	Pfam Anion-transporting ATPase
NTM_RS17830	COG5650	phosphatidylinositol metabolic process
NTM_RS17845	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NTM_RS17885	COG2001	Belongs to the MraZ family
NTM_RS17890	COG0275	rRNA processing
NTM_RS17900	COG0768	penicillin binding
NTM_RS17915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NTM_RS17920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NTM_RS17930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NTM_RS17935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NTM_RS17940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NTM_RS17960	COG1799	cell septum assembly
NTM_RS18005	COG3979	chitinase
NTM_RS18010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NTM_RS18015	COG0765	amino acid transport
NTM_RS18020	COG1126	abc transporter atp-binding protein
NTM_RS18025	COG2964	Protein conserved in bacteria
NTM_RS18030	COG0431	NADPH-dependent FMN reductase
NTM_RS18035	COG2066	Belongs to the glutaminase family
NTM_RS18055	COG3290	protein histidine kinase activity
NTM_RS18075	COG0589	response to stress
NTM_RS18080	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS18100	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS18105	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS18115	COG1309	transcriptional regulator
NTM_RS18120	COG1960	acyl-CoA dehydrogenase activity
NTM_RS18135	COG1024	Enoyl-CoA hydratase
NTM_RS18140	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS18145	COG1309	transcriptional regulator
NTM_RS18150	COG2030	dehydratase
NTM_RS18160	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS18180	COG0022	dehydrogenase e1 component
NTM_RS18185	COG0508	dehydrogenase complex catalyzes the overall conversion of
NTM_RS18190	COG1024	Enoyl-CoA hydratase
NTM_RS18200	COG1024	Enoyl-CoA hydratase
NTM_RS18210	COG1960	acyl-CoA dehydrogenase activity
NTM_RS18215	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NTM_RS18225	COG1024	Enoyl-CoA hydratase
NTM_RS18245	COG3386	PFAM SMP-30 Gluconolaconase
NTM_RS18260	COG1960	acyl-CoA dehydrogenase activity
NTM_RS18265	COG1960	acyl-CoA dehydrogenase activity
NTM_RS18300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS18310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS18315	COG0183	Belongs to the thiolase family
NTM_RS18330	COG2124	cytochrome p450
NTM_RS18335	COG1960	acyl-CoA dehydrogenase activity
NTM_RS18340	COG1960	acyl-CoA dehydrogenase activity
NTM_RS18355	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS18360	COG4638	Rieske (2fe-2S)
NTM_RS18440	COG0243	molybdopterin cofactor binding
NTM_RS18455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NTM_RS18465	COG0167	dihydroorotate dehydrogenase activity
NTM_RS18485	COG1968	undecaprenyl-diphosphatase activity
NTM_RS18535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NTM_RS18545	COG0140	phosphoribosyl-ATP diphosphatase activity
NTM_RS18550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NTM_RS18575	COG1116	anion transmembrane transporter activity
NTM_RS18605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NTM_RS18645	COG1222	aaa ATPase
NTM_RS18685	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NTM_RS18710	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS18740	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NTM_RS18760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NTM_RS18795	COG0300	oxidoreductase activity
NTM_RS18845	COG1174	glycine betaine transport
NTM_RS18875	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NTM_RS18880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NTM_RS18885	COG0463	Glycosyl transferase, family 2
NTM_RS18920	COG2272	Belongs to the type-B carboxylesterase lipase family
NTM_RS18930	COG1872	DUF167
NTM_RS18950	COG0583	DNA-binding transcription factor activity
NTM_RS18980	COG0539	negative regulation of cytoplasmic translation
NTM_RS18990	COG0237	dephospho-CoA kinase activity
NTM_RS18990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NTM_RS19040	COG3588	fructose-bisphosphate aldolase
NTM_RS19045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NTM_RS19075	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NTM_RS19075	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NTM_RS19090	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NTM_RS19100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NTM_RS19105	COG0300	oxidoreductase activity
NTM_RS19110	COG1960	acyl-CoA dehydrogenase activity
NTM_RS19130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NTM_RS19135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NTM_RS19135	COG0072	phenylalanine-tRNA ligase activity
NTM_RS19145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NTM_RS19150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NTM_RS19155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NTM_RS19160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NTM_RS19170	COG0137	argininosuccinate synthase activity
NTM_RS19175	COG0165	Argininosuccinate lyase
NTM_RS19200	COG0488	(ABC) transporter
NTM_RS19215	COG2835	tetraacyldisaccharide 4'-kinase activity
NTM_RS19250	COG0647	UMP catabolic process
NTM_RS19260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NTM_RS19280	COG0504	CTP synthase activity
NTM_RS19305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NTM_RS19310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NTM_RS19320	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NTM_RS19325	COG1160	GTP binding
NTM_RS19335	COG3046	protein related to deoxyribodipyrimidine photolyase
NTM_RS19345	COG0582	viral genome integration into host DNA
NTM_RS19405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NTM_RS19415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NTM_RS19420	COG0798	PFAM Bile acid sodium symporter
NTM_RS19430	COG0640	Transcriptional regulator
NTM_RS19455	COG4638	Rieske (2fe-2S)
NTM_RS19465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NTM_RS19475	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS19535	COG4257	antibiotic catabolic process
NTM_RS19550	COG1953	Uracil, thiamine, allantoin
NTM_RS19555	COG1268	BioY protein
NTM_RS19560	COG1122	ATPase activity
NTM_RS19570	COG4221	oxidoreductase activity
NTM_RS19610	COG1252	NADH dehydrogenase
NTM_RS19670	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NTM_RS19690	COG1573	uracil-dna glycosylase
NTM_RS19700	COG0753	catalase activity
NTM_RS19700	COG0693	protein deglycase activity
NTM_RS19705	COG0028	Belongs to the TPP enzyme family
NTM_RS19735	COG2814	Major facilitator Superfamily
NTM_RS19845	COG2272	Belongs to the type-B carboxylesterase lipase family
NTM_RS19855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NTM_RS19865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NTM_RS19870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NTM_RS19900	COG3976	FMN-binding domain protein
NTM_RS19900	COG1053	succinate dehydrogenase
NTM_RS19915	COG0653	protein targeting
NTM_RS19940	COG0509	glycine decarboxylation via glycine cleavage system
NTM_RS19945	COG1716	ATPase activity
NTM_RS19965	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NTM_RS19965	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NTM_RS19975	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS19980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NTM_RS19980	COG3321	synthase
NTM_RS19985	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS20025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NTM_RS20045	COG0778	Nitroreductase
NTM_RS20055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS20085	COG3391	amine dehydrogenase activity
NTM_RS20085	COG5651	PPE family
NTM_RS20095	COG2072	flavoprotein involved in K transport
NTM_RS20105	COG4221	oxidoreductase activity
NTM_RS20110	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NTM_RS20120	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NTM_RS20130	COG1253	flavin adenine dinucleotide binding
NTM_RS20135	COG1253	flavin adenine dinucleotide binding
NTM_RS20140	COG1840	ABC-type Fe3 transport system, periplasmic component
NTM_RS20150	COG3842	ATPase activity
NTM_RS20160	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NTM_RS20185	COG0831	urea catabolic process
NTM_RS20190	COG0832	Belongs to the urease beta subunit family
NTM_RS20195	COG0804	urea catabolic process
NTM_RS20200	COG0830	nickel cation binding
NTM_RS20205	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NTM_RS20210	COG0829	nickel cation binding
NTM_RS20215	COG3415	Transposase
NTM_RS20215	COG2801	Transposase and inactivated derivatives
NTM_RS20220	COG1252	NADH dehydrogenase
NTM_RS20225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS20265	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NTM_RS20275	COG0039	L-malate dehydrogenase activity
NTM_RS20300	COG4221	oxidoreductase activity
NTM_RS20310	COG0668	transmembrane transport
NTM_RS20360	COG1309	transcriptional regulator
NTM_RS20370	COG1289	transmembrane transporter activity
NTM_RS20380	COG1024	Enoyl-CoA hydratase
NTM_RS20395	COG2193	ferroxidase activity
NTM_RS20405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NTM_RS20410	COG0174	glutamine synthetase
NTM_RS20495	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NTM_RS20510	COG1376	ErfK ybiS ycfS ynhG family protein
NTM_RS20540	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NTM_RS20540	COG2070	2-Nitropropane dioxygenase
NTM_RS20545	COG3321	synthase
NTM_RS20545	COG0604	alcohol dehydrogenase
NTM_RS20545	COG3321	synthase
NTM_RS20545	COG0604	alcohol dehydrogenase
NTM_RS20640	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NTM_RS20640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NTM_RS20645	COG1819	glycosyl
NTM_RS20655	COG1819	glycosyl
NTM_RS20705	COG0604	alcohol dehydrogenase
NTM_RS20705	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS20705	COG3321	synthase
NTM_RS20710	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS20745	COG0243	molybdopterin cofactor binding
NTM_RS20755	COG2070	2-Nitropropane dioxygenase
NTM_RS20785	COG1546	Belongs to the CinA family
NTM_RS20785	COG1058	Belongs to the CinA family
NTM_RS20820	COG3022	response to hydroperoxide
NTM_RS20835	COG0784	Response regulator, receiver
NTM_RS20840	COG4251	negative regulation of phosphorylation
NTM_RS20855	COG2755	lipolytic protein G-D-S-L family
NTM_RS20860	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NTM_RS20915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NTM_RS20935	COG5651	PPE family
NTM_RS20935	COG3391	amine dehydrogenase activity
NTM_RS20970	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS20975	COG2318	DinB family
NTM_RS21020	COG4977	sequence-specific DNA binding
NTM_RS21035	COG1309	transcriptional regulator
NTM_RS21050	COG5006	permease, DMT superfamily
NTM_RS21055	COG0545	Peptidyl-prolyl cis-trans isomerase
NTM_RS21095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NTM_RS21100	COG0174	glutamine synthetase
NTM_RS21110	COG2378	regulation of single-species biofilm formation
NTM_RS21125	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS21205	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NTM_RS21210	COG1733	regulation of RNA biosynthetic process
NTM_RS21235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NTM_RS21250	COG2197	response regulator
NTM_RS21290	COG4974	Belongs to the 'phage' integrase family
NTM_RS21295	COG0076	glutamate decarboxylase activity
NTM_RS21310	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS21315	COG1902	pentaerythritol trinitrate reductase activity
NTM_RS21330	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NTM_RS21345	COG2814	Major facilitator Superfamily
NTM_RS21355	COG3804	dihydrodipicolinate reductase
NTM_RS21375	COG1024	Enoyl-CoA hydratase
NTM_RS21405	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS21410	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS21415	COG1024	Enoyl-CoA hydratase
NTM_RS21425	COG1024	Enoyl-CoA hydratase
NTM_RS21430	COG1024	Enoyl-CoA hydratase
NTM_RS21435	COG1024	Enoyl-CoA hydratase
NTM_RS21450	COG0640	Transcriptional regulator
NTM_RS21455	COG0346	lactoylglutathione lyase activity
NTM_RS21465	COG1126	abc transporter atp-binding protein
NTM_RS21470	COG0765	amino acid transport
NTM_RS21490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NTM_RS21515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NTM_RS21565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NTM_RS21570	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NTM_RS21575	COG1120	ATPase activity
NTM_RS21580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NTM_RS21580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NTM_RS21590	COG1132	(ABC) transporter
NTM_RS21595	COG1132	(ABC) transporter
NTM_RS21610	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NTM_RS21615	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NTM_RS21635	COG2814	Major facilitator Superfamily
NTM_RS21645	COG3842	ATPase activity
NTM_RS21655	COG1176	ABC-type spermidine putrescine transport system, permease component I
NTM_RS21660	COG1177	transmembrane transport
NTM_RS21680	COG1024	Enoyl-CoA hydratase
NTM_RS21710	COG1742	UPF0060 membrane protein
NTM_RS21795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NTM_RS21805	COG1271	oxidase subunit
NTM_RS21810	COG1294	oxidase, subunit
NTM_RS21815	COG4988	ABC transporter
NTM_RS21820	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NTM_RS21845	COG0069	glutamate synthase activity
NTM_RS21845	COG0070	glutamate synthase
NTM_RS21845	COG0067	glutamate synthase
NTM_RS21860	COG1403	HNH endonuclease
NTM_RS21870	COG0159	tryptophan synthase activity
NTM_RS21880	COG0134	indole-3-glycerol-phosphate synthase activity
NTM_RS21890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NTM_RS21900	COG1119	ATPase activity
NTM_RS21905	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NTM_RS21910	COG0107	imidazoleglycerol-phosphate synthase activity
NTM_RS21915	COG0483	inositol monophosphate 1-phosphatase activity
NTM_RS21920	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NTM_RS21925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NTM_RS21930	COG0131	Imidazoleglycerol-phosphate dehydratase
NTM_RS21935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NTM_RS21950	COG1280	lysine exporter protein (LysE YggA)
NTM_RS21970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NTM_RS21995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NTM_RS22000	COG1309	transcriptional regulator
NTM_RS22010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NTM_RS22015	COG0156	8-amino-7-oxononanoate synthase activity
NTM_RS22075	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NTM_RS22080	COG0252	asparaginase activity
NTM_RS22090	COG2501	S4 domain
NTM_RS22095	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NTM_RS22165	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NTM_RS22175	COG2304	oxidoreductase activity
NTM_RS22185	COG0714	Associated with various cellular activities
NTM_RS22195	COG3883	PFAM NLP P60 protein
NTM_RS22195	COG0791	NLP P60 protein
NTM_RS22205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NTM_RS22210	COG1309	transcriptional regulator
NTM_RS22220	COG0488	(ABC) transporter
NTM_RS22230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NTM_RS22235	COG2151	metal-sulfur cluster biosynthetic enzyme
NTM_RS22245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NTM_RS22250	COG0396	ATPase activity
NTM_RS22310	COG1301	dicarboxylic acid transport
NTM_RS22320	COG0109	protoheme IX farnesyltransferase activity
NTM_RS22330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NTM_RS22355	COG1403	HNH endonuclease
NTM_RS22360	COG1556	Lactate utilization protein
NTM_RS22365	COG1139	Iron-sulfur cluster binding protein
NTM_RS22370	COG0247	lactate metabolic process
NTM_RS22380	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NTM_RS22390	COG0149	triose-phosphate isomerase activity
NTM_RS22395	COG0126	phosphoglycerate kinase activity
NTM_RS22400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NTM_RS22415	COG1481	regulation of sporulation
NTM_RS22425	COG1660	Displays ATPase and GTPase activities
NTM_RS22430	COG0322	excinuclease ABC activity
NTM_RS22445	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NTM_RS22450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NTM_RS22450	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NTM_RS22465	COG0477	Major facilitator Superfamily
NTM_RS22485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NTM_RS22490	COG1704	LemA family
NTM_RS22525	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NTM_RS22535	COG1758	RNA polymerase activity
NTM_RS22550	COG0284	orotidine-5'-phosphate decarboxylase activity
NTM_RS22555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NTM_RS22560	COG0505	Belongs to the CarA family
NTM_RS22575	COG0540	Belongs to the ATCase OTCase family
NTM_RS22580	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NTM_RS22600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NTM_RS22605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NTM_RS22610	COG0006	proline dipeptidase activity
NTM_RS22625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NTM_RS22630	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NTM_RS22635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NTM_RS22645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NTM_RS22655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NTM_RS22660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NTM_RS22665	COG0432	Pfam Uncharacterised protein family UPF0047
NTM_RS22720	COG1349	DNA-binding transcription factor activity
NTM_RS22730	COG1653	transport
NTM_RS22740	COG0395	ABC-type sugar transport system, permease component
NTM_RS22745	COG3842	ATPase activity
NTM_RS22750	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS22755	COG0434	BtpA family
NTM_RS22760	COG1733	regulation of RNA biosynthetic process
NTM_RS22765	COG0183	Belongs to the thiolase family
NTM_RS22780	COG0142	geranyltranstransferase activity
NTM_RS22815	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NTM_RS22825	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS22830	COG1595	DNA-templated transcription, initiation
NTM_RS22860	COG2272	Belongs to the type-B carboxylesterase lipase family
NTM_RS22895	COG1960	acyl-CoA dehydrogenase activity
NTM_RS22905	COG2814	Major facilitator Superfamily
NTM_RS22915	COG3973	AAA domain
NTM_RS22925	COG0683	leucine binding
NTM_RS22960	COG0124	histidyl-tRNA synthetase
NTM_RS22970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NTM_RS22975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NTM_RS22980	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NTM_RS22985	COG0747	negative chemotaxis
NTM_RS22990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NTM_RS23020	COG3320	Male sterility
NTM_RS23020	COG1022	Amp-dependent synthetase and ligase
NTM_RS23035	COG2255	four-way junction helicase activity
NTM_RS23040	COG0632	four-way junction helicase activity
NTM_RS23045	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NTM_RS23095	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS23100	COG0300	oxidoreductase activity
NTM_RS23105	COG0531	amino acid
NTM_RS23115	COG0217	transcriptional regulatory protein
NTM_RS23120	COG1960	acyl-CoA dehydrogenase activity
NTM_RS23125	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NTM_RS23130	COG1946	Acyl-CoA thioesterase
NTM_RS23135	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NTM_RS23145	COG0438	transferase activity, transferring glycosyl groups
NTM_RS23150	COG1560	Kdo2-lipid A biosynthetic process
NTM_RS23155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NTM_RS23165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NTM_RS23180	COG0667	Aldo Keto reductase
NTM_RS23185	COG4762	Protein conserved in bacteria
NTM_RS23225	COG0366	Alpha amylase catalytic
NTM_RS23230	COG1609	Transcriptional regulator
NTM_RS23260	COG0596	Alpha beta hydrolase
NTM_RS23265	COG2770	Histidine kinase
NTM_RS23265	COG2208	phosphoserine phosphatase activity
NTM_RS23345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NTM_RS23365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NTM_RS23410	COG2807	transmembrane transport
NTM_RS23425	COG1295	ribonuclease BN
NTM_RS23480	COG0784	Response regulator, receiver
NTM_RS23500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NTM_RS23510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NTM_RS23515	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NTM_RS23585	COG1595	DNA-templated transcription, initiation
NTM_RS23590	COG2169	Transcriptional regulator
NTM_RS23590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NTM_RS23630	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NTM_RS23645	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NTM_RS23670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NTM_RS23675	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NTM_RS23680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NTM_RS23685	COG0531	amino acid
NTM_RS23690	COG0569	domain protein
NTM_RS23720	COG0756	dUTP diphosphatase activity
NTM_RS23825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NTM_RS23830	COG1388	LysM domain
NTM_RS23835	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NTM_RS23850	COG0513	Belongs to the DEAD box helicase family
NTM_RS23855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NTM_RS23860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NTM_RS23865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NTM_RS23875	COG0697	spore germination
NTM_RS23880	COG1196	nuclear chromosome segregation
NTM_RS23890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NTM_RS23895	COG1126	abc transporter atp-binding protein
NTM_RS23900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NTM_RS23905	COG0765	amino acid transport
NTM_RS23910	COG0765	amino acid transport
NTM_RS23925	COG2137	regulation of response to DNA damage stimulus
NTM_RS23930	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NTM_RS23945	COG0375	protein maturation
NTM_RS23950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NTM_RS23960	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NTM_RS23990	COG0298	carbon dioxide binding
NTM_RS23995	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NTM_RS24000	COG0298	carbon dioxide binding
NTM_RS24005	COG0409	Hydrogenase expression formation protein
NTM_RS24025	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
NTM_RS24040	COG1396	sequence-specific DNA binding
NTM_RS24050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NTM_RS24070	COG1674	ftsk spoiiie
NTM_RS24085	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NTM_RS24090	COG0745	RESPONSE REGULATOR receiver
NTM_RS24095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NTM_RS24100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NTM_RS24105	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
NTM_RS24115	COG0596	Alpha beta hydrolase
NTM_RS24120	COG3214	Protein conserved in bacteria
NTM_RS24130	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NTM_RS24155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NTM_RS24165	COG1522	sequence-specific DNA binding
NTM_RS24170	COG0686	Belongs to the AlaDH PNT family
NTM_RS24175	COG3012	SEC-C Motif Domain Protein
NTM_RS24190	COG1185	polyribonucleotide nucleotidyltransferase activity
NTM_RS24195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NTM_RS24215	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NTM_RS24250	COG1024	Enoyl-CoA hydratase
NTM_RS24265	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NTM_RS24270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NTM_RS24275	COG0481	GTPase activity
NTM_RS24275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NTM_RS24285	COG0195	Participates in both transcription termination and antitermination
NTM_RS24290	COG0779	Required for maturation of 30S ribosomal subunits
NTM_RS24305	COG0442	prolyl-tRNA aminoacylation
NTM_RS24310	COG0300	oxidoreductase activity
NTM_RS24315	COG0583	DNA-binding transcription factor activity
NTM_RS24325	COG1648	precorrin-2 dehydrogenase activity
NTM_RS24325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NTM_RS24350	COG0579	oxidoreductase
NTM_RS24365	COG1595	DNA-templated transcription, initiation
NTM_RS24370	COG0745	RESPONSE REGULATOR receiver
NTM_RS24375	COG2205	protein histidine kinase activity
NTM_RS24380	COG1122	ATPase activity
NTM_RS24395	COG0310	cobalt ion transport
NTM_RS24410	COG1403	HNH endonuclease
NTM_RS24415	COG2186	Transcriptional regulator
NTM_RS24425	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS24430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NTM_RS24440	COG0367	asparagine synthase
NTM_RS24510	COG0750	zinc metalloprotease
NTM_RS24515	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NTM_RS24535	COG0415	Belongs to the DNA photolyase family
NTM_RS24570	COG1946	Acyl-CoA thioesterase
NTM_RS24575	COG2130	NADP-dependent
NTM_RS24590	COG1403	HNH endonuclease
NTM_RS24595	COG1960	acyl-CoA dehydrogenase activity
NTM_RS24685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NTM_RS24695	COG0233	cytoplasmic translational termination
NTM_RS24700	COG0528	UMP kinase activity
NTM_RS24705	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NTM_RS24720	COG1136	(ABC) transporter
NTM_RS24735	COG0154	amidase activity
NTM_RS24740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NTM_RS24745	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NTM_RS24750	COG0052	Belongs to the universal ribosomal protein uS2 family
NTM_RS24765	COG0596	Alpha beta hydrolase
NTM_RS24770	COG4974	Belongs to the 'phage' integrase family
NTM_RS24795	COG0792	nuclease activity
NTM_RS24815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NTM_RS24840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS24860	COG1309	transcriptional regulator
NTM_RS24865	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS24875	COG2124	cytochrome p450
NTM_RS24885	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS24900	COG0714	Associated with various cellular activities
NTM_RS24910	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS24915	COG1309	transcriptional regulator
NTM_RS24925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NTM_RS24960	COG2239	Acts as a magnesium transporter
NTM_RS24975	COG1686	Belongs to the peptidase S11 family
NTM_RS24980	COG1686	Belongs to the peptidase S11 family
NTM_RS24995	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NTM_RS25015	COG1304	FMN binding
NTM_RS25025	COG1254	Belongs to the acylphosphatase family
NTM_RS25035	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NTM_RS25040	COG0571	ribonuclease III activity
NTM_RS25050	COG3599	regulation of cell shape
NTM_RS25060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NTM_RS25075	COG0742	ribosomal rna small subunit methyltransferase
NTM_RS25100	COG0656	L-ascorbic acid biosynthetic process
NTM_RS25115	COG2847	Copper chaperone PCu(A)C
NTM_RS25120	COG2837	iron assimilation
NTM_RS25135	COG1461	Dihydroxyacetone kinase
NTM_RS25145	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NTM_RS25165	COG1181	Belongs to the D-alanine--D-alanine ligase family
NTM_RS25170	COG0626	cystathionine gamma-synthase activity
NTM_RS25180	COG1920	GTP binding
NTM_RS25185	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NTM_RS25200	COG0066	3-isopropylmalate dehydratase activity
NTM_RS25205	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NTM_RS25225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NTM_RS25230	COG0179	Fumarylacetoacetate (FAA) hydrolase
NTM_RS25235	COG2271	Major facilitator Superfamily
NTM_RS25245	COG0473	3-isopropylmalate dehydrogenase activity
NTM_RS25260	COG0655	NAD(P)H dehydrogenase (quinone) activity
NTM_RS25270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NTM_RS25275	COG0440	acetolactate synthase activity
NTM_RS25295	COG2133	pyrroloquinoline quinone binding
NTM_RS25300	COG2205	protein histidine kinase activity
NTM_RS25305	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NTM_RS25310	COG0205	6-phosphofructokinase activity
NTM_RS25315	COG0154	amidase activity
NTM_RS25320	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NTM_RS25330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NTM_RS25340	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS25360	COG0482	sulfurtransferase activity
NTM_RS25380	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NTM_RS25390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NTM_RS25405	COG0110	maltose O-acetyltransferase activity
NTM_RS25410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NTM_RS25415	COG1115	amino acid carrier protein
NTM_RS25440	COG1119	ATPase activity
NTM_RS25455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NTM_RS25460	COG0560	Phosphoserine phosphatase
NTM_RS25460	COG3830	Belongs to the UPF0237 family
NTM_RS25470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NTM_RS25475	COG1064	alcohol dehydrogenase
NTM_RS25490	COG2197	response regulator
NTM_RS25495	COG2201	protein-glutamate methylesterase activity
NTM_RS25505	COG3037	sugar-specific permease SgaT UlaA
NTM_RS25515	COG1472	Belongs to the glycosyl hydrolase 3 family
NTM_RS25535	COG1309	transcriptional regulator
NTM_RS25540	COG0644	oxidoreductase
NTM_RS25570	COG2072	flavoprotein involved in K transport
NTM_RS25585	COG3284	Transcriptional regulator
NTM_RS25605	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NTM_RS25610	COG1780	Probably involved in ribonucleotide reductase function
NTM_RS25620	COG0431	NADPH-dependent FMN reductase
NTM_RS25675	COG0028	Belongs to the TPP enzyme family
NTM_RS25690	COG1793	dna ligase
NTM_RS25695	COG1966	Carbon starvation protein
NTM_RS25705	COG0477	Major facilitator Superfamily
NTM_RS25720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NTM_RS25745	COG2072	flavoprotein involved in K transport
NTM_RS25775	COG2124	cytochrome p450
NTM_RS25785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS25800	COG2124	cytochrome p450
NTM_RS25810	COG0183	Belongs to the thiolase family
NTM_RS25815	COG1960	acyl-CoA dehydrogenase activity
NTM_RS25830	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS25840	COG1024	Enoyl-CoA hydratase
NTM_RS25845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NTM_RS25850	COG0300	oxidoreductase activity
NTM_RS25855	COG1024	Enoyl-CoA hydratase
NTM_RS25870	COG1024	Enoyl-CoA hydratase
NTM_RS25880	COG1024	Enoyl-CoA hydratase
NTM_RS25890	COG1024	Enoyl-CoA hydratase
NTM_RS25895	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS25900	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS25915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS25920	COG1802	Transcriptional regulator
NTM_RS25925	COG1960	acyl-CoA dehydrogenase activity
NTM_RS25930	COG0183	Belongs to the thiolase family
NTM_RS25940	COG1960	acyl-CoA dehydrogenase activity
NTM_RS25945	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS25955	COG2072	flavoprotein involved in K transport
NTM_RS25985	COG1960	acyl-CoA dehydrogenase activity
NTM_RS26055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS26060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS26085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NTM_RS26125	COG4638	Rieske (2fe-2S)
NTM_RS26170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NTM_RS26190	COG1403	HNH endonuclease
NTM_RS26195	COG2272	Belongs to the type-B carboxylesterase lipase family
NTM_RS26215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS26230	COG2814	Major facilitator Superfamily
NTM_RS26245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NTM_RS26290	COG2354	Protein conserved in bacteria
NTM_RS26325	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS26330	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS26345	COG1960	acyl-CoA dehydrogenase activity
NTM_RS26355	COG1024	Enoyl-CoA hydratase
NTM_RS26365	COG2124	cytochrome p450
NTM_RS26370	COG1024	Enoyl-CoA hydratase
NTM_RS26375	COG2186	Transcriptional regulator
NTM_RS26380	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS26395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS26405	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS26455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS26475	COG1960	acyl-CoA dehydrogenase activity
NTM_RS26480	COG1960	acyl-CoA dehydrogenase activity
NTM_RS26515	COG3707	response regulator
NTM_RS26535	COG0531	amino acid
NTM_RS26650	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NTM_RS26655	COG2177	Part of the ABC transporter FtsEX involved in
NTM_RS26660	COG2884	Cell division ATP-binding protein ftsE
NTM_RS26670	COG0668	transmembrane transport
NTM_RS26675	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NTM_RS26690	COG0483	inositol monophosphate 1-phosphatase activity
NTM_RS26700	COG1960	acyl-CoA dehydrogenase activity
NTM_RS26705	COG1473	amidohydrolase
NTM_RS26710	COG0243	molybdopterin cofactor binding
NTM_RS26715	COG0604	alcohol dehydrogenase
NTM_RS26720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NTM_RS26750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS26755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NTM_RS26765	COG1960	acyl-CoA dehydrogenase activity
NTM_RS26780	COG4257	antibiotic catabolic process
NTM_RS26785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NTM_RS26805	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NTM_RS26810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NTM_RS26815	COG0649	NAD binding
NTM_RS26835	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NTM_RS26840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NTM_RS26850	COG0713	ATP synthesis coupled electron transport
NTM_RS26870	COG1024	Enoyl-CoA hydratase
NTM_RS26890	COG2017	converts alpha-aldose to the beta-anomer
NTM_RS26910	COG4214	carbohydrate transport
NTM_RS26925	COG1879	ABC-type sugar transport system periplasmic component
NTM_RS26935	COG1172	Belongs to the binding-protein-dependent transport system permease family
NTM_RS26945	COG1609	Transcriptional regulator
NTM_RS26960	COG2160	L-arabinose isomerase activity
NTM_RS27010	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS27030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NTM_RS27035	COG1960	acyl-CoA dehydrogenase activity
NTM_RS27040	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS27045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS27055	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NTM_RS27060	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NTM_RS27095	COG0531	amino acid
NTM_RS27100	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS27105	COG2199	diguanylate cyclase activity
NTM_RS27105	COG2203	Gaf domain
NTM_RS27115	COG1063	alcohol dehydrogenase
NTM_RS27120	COG5651	PPE family
NTM_RS27125	COG4251	negative regulation of phosphorylation
NTM_RS27150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NTM_RS27155	COG0477	Major facilitator Superfamily
NTM_RS27205	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NTM_RS27230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS27235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NTM_RS27240	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS27255	COG2072	flavoprotein involved in K transport
NTM_RS27280	COG1414	Transcriptional regulator
NTM_RS27290	COG1902	pentaerythritol trinitrate reductase activity
NTM_RS27290	COG0446	pyridine nucleotide-disulphide oxidoreductase
NTM_RS27305	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS27310	COG2072	flavoprotein involved in K transport
NTM_RS27315	COG0318	PFAM AMP-dependent synthetase and ligase
NTM_RS27330	COG1024	Enoyl-CoA hydratase
NTM_RS27335	COG1960	acyl-CoA dehydrogenase activity
NTM_RS27380	COG1053	succinate dehydrogenase
NTM_RS27390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NTM_RS27405	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NTM_RS27410	COG1716	ATPase activity
NTM_RS27410	COG5001	Diguanylate cyclase
NTM_RS27415	COG2186	Transcriptional regulator
NTM_RS27425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NTM_RS27435	COG0596	Alpha beta hydrolase
NTM_RS27475	COG0406	alpha-ribazole phosphatase activity
NTM_RS27490	COG0640	Transcriptional regulator
NTM_RS27525	COG1454	alcohol dehydrogenase
NTM_RS27540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NTM_RS27550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NTM_RS27560	COG3485	protocatechuate 3,4-dioxygenase
NTM_RS27565	COG3485	protocatechuate 3,4-dioxygenase
NTM_RS27570	COG0477	Major facilitator Superfamily
NTM_RS27575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NTM_RS27580	COG1309	transcriptional regulator
NTM_RS27585	COG0326	Molecular chaperone. Has ATPase activity
NTM_RS27605	COG1615	UPF0182 protein
NTM_RS27610	COG3480	Lon protease (S16) C-terminal proteolytic domain
NTM_RS27625	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NTM_RS27670	COG0596	Alpha beta hydrolase
NTM_RS27675	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NTM_RS27715	COG0513	Belongs to the DEAD box helicase family
NTM_RS27730	COG0406	alpha-ribazole phosphatase activity
NTM_RS27750	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NTM_RS27755	COG1597	lipid kinase activity
NTM_RS27770	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NTM_RS27775	COG5662	AntiSigma factor
NTM_RS27780	COG1595	DNA-templated transcription, initiation
NTM_RS27785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NTM_RS27810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NTM_RS27820	COG0656	L-ascorbic acid biosynthetic process
NTM_RS27840	COG2326	polyphosphate kinase activity
NTM_RS27845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NTM_RS27860	COG0653	protein targeting
NTM_RS27865	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NTM_RS27880	COG5401	PFAM Sporulation and spore germination
NTM_RS27885	COG5002	protein histidine kinase activity
NTM_RS27890	COG0745	RESPONSE REGULATOR receiver
NTM_RS27910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NTM_RS27930	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NTM_RS27935	COG0531	amino acid
NTM_RS27940	COG1482	cell wall glycoprotein biosynthetic process
NTM_RS27950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NTM_RS27975	COG0778	Nitroreductase
NTM_RS27975	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
NTM_RS28000	COG1091	dTDP-4-dehydrorhamnose reductase activity
NTM_RS28005	COG1316	TRANSCRIPTIONal
NTM_RS28045	COG1755	Isoprenylcysteine carboxyl methyltransferase
NTM_RS28050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NTM_RS28055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NTM_RS28070	COG0446	pyridine nucleotide-disulphide oxidoreductase
NTM_RS28075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NTM_RS28085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NTM_RS28100	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NTM_RS28140	COG2226	methyltransferase
NTM_RS28155	COG0297	glycogen (starch) synthase activity
NTM_RS28160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NTM_RS28170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NTM_RS28175	COG0489	protein tyrosine kinase activity
NTM_RS28190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NTM_RS28200	COG0424	maF-like protein
NTM_RS28215	COG2755	lipolytic protein G-D-S-L family
NTM_RS28215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NTM_RS28235	COG0659	secondary active sulfate transmembrane transporter activity
NTM_RS28245	COG4770	biotin carboxylase activity
NTM_RS28310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NTM_RS28320	COG1522	sequence-specific DNA binding
NTM_RS28330	COG1012	belongs to the aldehyde dehydrogenase family
NTM_RS28335	COG0300	oxidoreductase activity
NTM_RS28340	COG1309	transcriptional regulator
NTM_RS28350	COG1201	RNA secondary structure unwinding
NTM_RS28385	COG1309	transcriptional regulator
NTM_RS28395	COG1028	Short-chain dehydrogenase reductase Sdr
NTM_RS28405	COG0564	pseudouridine synthase activity
NTM_RS28435	COG1473	amidohydrolase
NTM_RS28435	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NTM_RS28450	COG3180	Ammonia monooxygenase
NTM_RS28460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate