locus-tag	class	description
FOY43_RS00145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOY43_RS00190	COG1435	thymidine kinase activity
FOY43_RS00225	COG0358	DNA primase activity
FOY43_RS00300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOY43_RS00320	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FOY43_RS00360	COG3842	ATPase activity
FOY43_RS00435	COG0194	GDP metabolic process
FOY43_RS00440	COG1263	PTS System
FOY43_RS00440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOY43_RS00440	COG2190	(PTS) system
FOY43_RS00470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOY43_RS00505	COG2376	Dihydroxyacetone kinase
FOY43_RS00570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOY43_RS00570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOY43_RS00700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOY43_RS00765	COG0571	ribonuclease III activity
FOY43_RS00810	COG0813	purine-nucleoside phosphorylase activity
FOY43_RS00910	COG0217	transcriptional regulatory protein
FOY43_RS00925	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOY43_RS00945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOY43_RS00950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOY43_RS00955	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOY43_RS00965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOY43_RS00970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOY43_RS00975	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOY43_RS01040	COG1739	Uncharacterized protein family UPF0029
FOY43_RS01060	COG0295	cytidine deaminase activity
FOY43_RS01065	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOY43_RS01080	COG0698	ribose 5-phosphate isomerase
FOY43_RS01410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOY43_RS01490	COG1307	EDD domain protein, DegV family
FOY43_RS01625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOY43_RS01675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOY43_RS01785	COG1136	(ABC) transporter
FOY43_RS01800	COG1136	(ABC) transporter
FOY43_RS01885	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOY43_RS01890	COG0081	regulation of translation
FOY43_RS01960	COG1187	pseudouridine synthase activity
FOY43_RS01990	COG0776	regulation of translation
FOY43_RS02105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOY43_RS02290	COG0254	rRNA binding
FOY43_RS02395	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOY43_RS02405	COG0564	pseudouridine synthase activity
FOY43_RS02430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOY43_RS02455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOY43_RS02575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOY43_RS02585	COG0202	RNA polymerase activity
FOY43_RS02595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOY43_RS02600	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOY43_RS02605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOY43_RS02615	COG0563	adenylate kinase activity
FOY43_RS02640	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOY43_RS02645	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOY43_RS02665	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOY43_RS02670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOY43_RS02675	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOY43_RS02725	COG0051	transcription antitermination factor activity, RNA binding
FOY43_RS02755	COG0802	atpase or kinase
FOY43_RS02780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOY43_RS02800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOY43_RS02810	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOY43_RS02905	COG0681	Belongs to the peptidase S26 family
FOY43_RS02940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOY43_RS02945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOY43_RS02975	COG0592	DNA-directed DNA polymerase activity
FOY43_RS03130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOY43_RS03290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOY43_RS03380	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOY43_RS03385	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOY43_RS03415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOY43_RS03500	COG1373	ATPase (AAA superfamily
FOY43_RS03520	COG0556	nucleotide-excision repair
FOY43_RS03600	COG0280	phosphate acetyltransferase
FOY43_RS03605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOY43_RS03670	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOY43_RS03675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOY43_RS03770	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOY43_RS03775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOY43_RS03805	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ