locus-tag	class	description
BC94_RS00095	COG3845	ABC transporter
BC94_RS00240	COG0528	UMP kinase activity
BC94_RS00245	COG0233	cytoplasmic translational termination
BC94_RS00285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BC94_RS00290	COG0084	hydrolase, TatD family'
BC94_RS00320	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BC94_RS00370	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BC94_RS00370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BC94_RS00420	COG1187	pseudouridine synthase activity
BC94_RS00445	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BC94_RS00475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC94_RS00605	COG0698	ribose 5-phosphate isomerase
BC94_RS00620	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BC94_RS00745	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BC94_RS00750	COG0280	phosphate acetyltransferase
BC94_RS00755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BC94_RS00760	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BC94_RS00865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC94_RS01025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BC94_RS01090	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BC94_RS01125	COG0194	GDP metabolic process
BC94_RS01165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BC94_RS01180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC94_RS01335	COG2255	four-way junction helicase activity
BC94_RS01595	COG0629	single-stranded DNA binding
BC94_RS01675	COG1461	Dihydroxyacetone kinase
BC94_RS01845	COG0813	purine-nucleoside phosphorylase activity
BC94_RS01875	COG4221	oxidoreductase activity
BC94_RS02030	COG0556	nucleotide-excision repair
BC94_RS02145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BC94_RS02150	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BC94_RS02345	COG1214	PFAM Peptidase M22, glycoprotease
BC94_RS02490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BC94_RS02600	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BC94_RS02665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC94_RS02905	COG0813	purine-nucleoside phosphorylase activity
BC94_RS02915	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BC94_RS02940	COG1122	ATPase activity
BC94_RS02970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BC94_RS02980	COG0563	adenylate kinase activity
BC94_RS03050	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BC94_RS03055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BC94_RS03135	COG0051	transcription antitermination factor activity, RNA binding
BC94_RS03140	COG0776	regulation of translation
BC94_RS03165	COG1187	pseudouridine synthase activity
BC94_RS03190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BC94_RS03200	COG0254	rRNA binding
BC94_RS03215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC94_RS03270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BC94_RS03470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BC94_RS03685	COG1739	Uncharacterized protein family UPF0029
BC94_RS03720	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BC94_RS03730	COG0564	pseudouridine synthase activity
BC94_RS03760	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC94_RS03790	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BC94_RS03795	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BC94_RS03805	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BC94_RS03850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BC94_RS03935	COG0582	viral genome integration into host DNA
BC94_RS03985	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BC94_RS03990	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BC94_RS04000	COG0736	holo-[acyl-carrier-protein] synthase activity
BC94_RS04155	COG1136	(ABC) transporter