locus-tag	class	description
CH336_RS00100	COG3845	ABC transporter
CH336_RS00265	COG0528	UMP kinase activity
CH336_RS00270	COG0233	cytoplasmic translational termination
CH336_RS00300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CH336_RS00305	COG0084	hydrolase, TatD family'
CH336_RS00350	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH336_RS00405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH336_RS00405	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CH336_RS00455	COG1187	pseudouridine synthase activity
CH336_RS00480	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CH336_RS00510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH336_RS00655	COG0698	ribose 5-phosphate isomerase
CH336_RS00670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CH336_RS00790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CH336_RS00795	COG0280	phosphate acetyltransferase
CH336_RS00800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CH336_RS00805	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CH336_RS00960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH336_RS01125	COG2255	four-way junction helicase activity
CH336_RS01305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH336_RS01345	COG0194	GDP metabolic process
CH336_RS01380	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CH336_RS01455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH336_RS01590	COG1263	PTS System
CH336_RS01590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH336_RS01770	COG0629	single-stranded DNA binding
CH336_RS01860	COG1461	Dihydroxyacetone kinase
CH336_RS01870	COG0571	ribonuclease III activity
CH336_RS01975	COG4221	oxidoreductase activity
CH336_RS02155	COG0556	nucleotide-excision repair
CH336_RS02270	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CH336_RS02275	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CH336_RS02490	COG1214	PFAM Peptidase M22, glycoprotease
CH336_RS02830	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CH336_RS02895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CH336_RS03165	COG0813	purine-nucleoside phosphorylase activity
CH336_RS03175	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH336_RS03200	COG1122	ATPase activity
CH336_RS03230	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH336_RS03240	COG0563	adenylate kinase activity
CH336_RS03305	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CH336_RS03310	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CH336_RS03390	COG0051	transcription antitermination factor activity, RNA binding
CH336_RS03395	COG0776	regulation of translation
CH336_RS03420	COG1187	pseudouridine synthase activity
CH336_RS03445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CH336_RS03455	COG0254	rRNA binding
CH336_RS03470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH336_RS03550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH336_RS03765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CH336_RS04195	COG1739	Uncharacterized protein family UPF0029
CH336_RS04235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CH336_RS04245	COG0564	pseudouridine synthase activity
CH336_RS04275	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CH336_RS04305	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CH336_RS04310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH336_RS04320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CH336_RS04365	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CH336_RS04460	COG0582	viral genome integration into host DNA
CH336_RS04510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CH336_RS04515	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CH336_RS04525	COG0736	holo-[acyl-carrier-protein] synthase activity
CH336_RS04700	COG1136	(ABC) transporter