locus-tag	class	description
CH321_RS00100	COG3845	ABC transporter
CH321_RS00265	COG0528	UMP kinase activity
CH321_RS00270	COG0233	cytoplasmic translational termination
CH321_RS00300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CH321_RS00305	COG0084	hydrolase, TatD family'
CH321_RS00350	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH321_RS00405	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CH321_RS00405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH321_RS00455	COG1187	pseudouridine synthase activity
CH321_RS00480	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CH321_RS00510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH321_RS00660	COG0698	ribose 5-phosphate isomerase
CH321_RS00675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CH321_RS00795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CH321_RS00800	COG0280	phosphate acetyltransferase
CH321_RS00805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CH321_RS00810	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CH321_RS00960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH321_RS01155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH321_RS01230	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CH321_RS01265	COG0194	GDP metabolic process
CH321_RS01305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH321_RS01485	COG2255	four-way junction helicase activity
CH321_RS01590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH321_RS01590	COG1263	PTS System
CH321_RS01780	COG0629	single-stranded DNA binding
CH321_RS01860	COG1461	Dihydroxyacetone kinase
CH321_RS01870	COG0571	ribonuclease III activity
CH321_RS02065	COG0813	purine-nucleoside phosphorylase activity
CH321_RS02095	COG4221	oxidoreductase activity
CH321_RS02275	COG0556	nucleotide-excision repair
CH321_RS02395	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CH321_RS02400	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CH321_RS02615	COG1214	PFAM Peptidase M22, glycoprotease
CH321_RS02955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CH321_RS03020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CH321_RS03290	COG0813	purine-nucleoside phosphorylase activity
CH321_RS03300	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH321_RS03325	COG1122	ATPase activity
CH321_RS03355	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH321_RS03365	COG0563	adenylate kinase activity
CH321_RS03430	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CH321_RS03435	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CH321_RS03515	COG0051	transcription antitermination factor activity, RNA binding
CH321_RS03520	COG0776	regulation of translation
CH321_RS03545	COG1187	pseudouridine synthase activity
CH321_RS03570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CH321_RS03580	COG0254	rRNA binding
CH321_RS03595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH321_RS03675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH321_RS03890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CH321_RS04315	COG1739	Uncharacterized protein family UPF0029
CH321_RS04355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CH321_RS04365	COG0564	pseudouridine synthase activity
CH321_RS04395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CH321_RS04425	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CH321_RS04430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH321_RS04440	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CH321_RS04485	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CH321_RS04590	COG0582	viral genome integration into host DNA
CH321_RS04640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CH321_RS04645	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CH321_RS04655	COG0736	holo-[acyl-carrier-protein] synthase activity
CH321_RS04835	COG1136	(ABC) transporter