locus-tag	class	description
CH324_RS00105	COG3845	ABC transporter
CH324_RS00255	COG0528	UMP kinase activity
CH324_RS00260	COG0233	cytoplasmic translational termination
CH324_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CH324_RS00295	COG0084	hydrolase, TatD family'
CH324_RS00325	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH324_RS00380	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CH324_RS00380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH324_RS00430	COG1187	pseudouridine synthase activity
CH324_RS00460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CH324_RS00490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH324_RS00650	COG0698	ribose 5-phosphate isomerase
CH324_RS00665	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CH324_RS00785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CH324_RS00790	COG0280	phosphate acetyltransferase
CH324_RS00795	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CH324_RS00800	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CH324_RS00970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH324_RS01170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH324_RS01240	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CH324_RS01275	COG0194	GDP metabolic process
CH324_RS01315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH324_RS01500	COG2255	four-way junction helicase activity
CH324_RS01605	COG1263	PTS System
CH324_RS01605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH324_RS01805	COG0629	single-stranded DNA binding
CH324_RS01885	COG1461	Dihydroxyacetone kinase
CH324_RS01895	COG0571	ribonuclease III activity
CH324_RS01985	COG0813	purine-nucleoside phosphorylase activity
CH324_RS02015	COG4221	oxidoreductase activity
CH324_RS02210	COG0556	nucleotide-excision repair
CH324_RS02340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CH324_RS02345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CH324_RS02580	COG1214	PFAM Peptidase M22, glycoprotease
CH324_RS02860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CH324_RS02975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CH324_RS03040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CH324_RS03270	COG0813	purine-nucleoside phosphorylase activity
CH324_RS03280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH324_RS03305	COG1122	ATPase activity
CH324_RS03335	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH324_RS03345	COG0563	adenylate kinase activity
CH324_RS03405	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CH324_RS03410	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CH324_RS03490	COG0051	transcription antitermination factor activity, RNA binding
CH324_RS03495	COG0776	regulation of translation
CH324_RS03520	COG1187	pseudouridine synthase activity
CH324_RS03545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CH324_RS03555	COG0254	rRNA binding
CH324_RS03570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH324_RS03655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH324_RS03915	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CH324_RS04275	COG1739	Uncharacterized protein family UPF0029
CH324_RS04310	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CH324_RS04320	COG0564	pseudouridine synthase activity
CH324_RS04350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CH324_RS04385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CH324_RS04390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH324_RS04400	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CH324_RS04445	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CH324_RS04540	COG0582	viral genome integration into host DNA
CH324_RS04590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CH324_RS04595	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CH324_RS04605	COG0736	holo-[acyl-carrier-protein] synthase activity
CH324_RS04785	COG1136	(ABC) transporter