locus-tag	class	description
DMC14_RS00015	COG2501	S4 domain
DMC14_RS00020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DMC14_RS00195	COG0556	nucleotide-excision repair
DMC14_RS00235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DMC14_RS00240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DMC14_RS00265	COG0222	ribosome binding
DMC14_RS00270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DMC14_RS00300	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMC14_RS00320	COG0564	pseudouridine synthase activity
DMC14_RS00325	COG1739	Uncharacterized protein family UPF0029
DMC14_RS00390	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DMC14_RS00405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DMC14_RS00530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DMC14_RS00535	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DMC14_RS00580	COG0813	purine-nucleoside phosphorylase activity
DMC14_RS00590	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DMC14_RS00605	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMC14_RS00610	COG0360	Binds together with S18 to 16S ribosomal RNA
DMC14_RS00620	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMC14_RS00675	COG1435	thymidine kinase activity
DMC14_RS00720	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DMC14_RS00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMC14_RS00760	COG0492	ferredoxin-NADP+ reductase activity
DMC14_RS00845	COG1187	pseudouridine synthase activity
DMC14_RS00875	COG0301	tRNA thio-modification
DMC14_RS00885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMC14_RS00925	COG0359	binds to the 23S rRNA
DMC14_RS00980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DMC14_RS01025	COG1597	lipid kinase activity
DMC14_RS01040	COG3763	UPF0154 protein
DMC14_RS01110	COG0081	regulation of translation
DMC14_RS01180	COG0335	large ribosomal subunit rRNA binding
DMC14_RS01190	COG0228	four-way junction DNA binding
DMC14_RS01260	COG1323	Belongs to the UPF0348 family
DMC14_RS01530	COG0193	aminoacyl-tRNA hydrolase activity
DMC14_RS01635	COG0194	GDP metabolic process
DMC14_RS01650	COG1162	GTPase activity
DMC14_RS01665	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DMC14_RS01695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DMC14_RS01750	COG0632	four-way junction helicase activity
DMC14_RS01805	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DMC14_RS01830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMC14_RS01895	COG1481	regulation of sporulation
DMC14_RS01945	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMC14_RS01970	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DMC14_RS01975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DMC14_RS02005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMC14_RS02080	COG0051	transcription antitermination factor activity, RNA binding
DMC14_RS02095	COG0089	rRNA binding
DMC14_RS02110	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMC14_RS02125	COG0255	Belongs to the universal ribosomal protein uL29 family
DMC14_RS02135	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMC14_RS02160	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMC14_RS02165	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DMC14_RS02170	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMC14_RS02175	COG0200	Binds to the 23S rRNA
DMC14_RS02200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DMC14_RS02205	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMC14_RS02225	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DMC14_RS02260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMC14_RS02300	COG0149	triose-phosphate isomerase activity
DMC14_RS02350	COG2001	Belongs to the MraZ family
DMC14_RS02365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DMC14_RS02370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DMC14_RS02380	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DMC14_RS02390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMC14_RS02470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMC14_RS02525	COG1122	ATPase activity
DMC14_RS02545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMC14_RS02595	COG0632	four-way junction helicase activity
DMC14_RS02670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMC14_RS02680	COG0484	heat shock protein binding
DMC14_RS02715	COG0776	regulation of translation
DMC14_RS02905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMC14_RS03045	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMC14_RS03050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMC14_RS03070	COG0268	Binds directly to 16S ribosomal RNA
DMC14_RS03160	COG0254	rRNA binding
DMC14_RS03255	COG0230	Belongs to the bacterial ribosomal protein bL34 family