locus-tag	class	description
GQS07_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GQS07_RS00010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GQS07_RS00035	COG0306	phosphate transporter
GQS07_RS00045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQS07_RS00050	COG2855	membrane
GQS07_RS00080	COG3781	membrane
GQS07_RS00090	COG0450	alkyl hydroperoxide reductase
GQS07_RS00105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GQS07_RS00110	COG1674	ftsk spoiiie
GQS07_RS00125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQS07_RS00125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQS07_RS00145	COG2837	iron assimilation
GQS07_RS00155	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GQS07_RS00160	COG1063	alcohol dehydrogenase
GQS07_RS00165	COG1396	sequence-specific DNA binding
GQS07_RS00170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GQS07_RS00175	COG0587	DNA-directed DNA polymerase activity
GQS07_RS00195	COG2171	N-acyltransferase activity
GQS07_RS00200	COG1368	sulfuric ester hydrolase activity
GQS07_RS00205	COG0463	Glycosyl transferase, family 2
GQS07_RS00220	COG1696	Membrane protein involved in D-alanine export
GQS07_RS00225	COG1388	LysM domain
GQS07_RS00225	COG3942	CHAP domain
GQS07_RS00235	COG0018	arginyl-trna synthetase
GQS07_RS00285	COG0811	peptide transport
GQS07_RS00290	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GQS07_RS00295	COG1960	acyl-CoA dehydrogenase activity
GQS07_RS00300	COG2205	protein histidine kinase activity
GQS07_RS00300	COG0784	Response regulator, receiver
GQS07_RS00300	COG5002	protein histidine kinase activity
GQS07_RS00325	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GQS07_RS00345	COG2885	chlorophyll binding
GQS07_RS00370	COG2207	Transcriptional regulator
GQS07_RS00370	COG4753	response regulator
GQS07_RS00400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS07_RS00405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQS07_RS00435	COG0254	rRNA binding
GQS07_RS00450	COG0463	Glycosyl transferase, family 2
GQS07_RS00455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQS07_RS00460	COG1132	(ABC) transporter
GQS07_RS00470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GQS07_RS00475	COG0105	UTP biosynthetic process
GQS07_RS00480	COG0387	Pfam Sodium calcium exchanger
GQS07_RS00500	COG1393	Belongs to the ArsC family
GQS07_RS00510	COG0114	fumarate hydratase activity
GQS07_RS00515	COG0133	tryptophan synthase activity
GQS07_RS00525	COG0488	(ABC) transporter
GQS07_RS00530	COG1408	metallophosphoesterase
GQS07_RS00535	COG0745	RESPONSE REGULATOR receiver
GQS07_RS00535	COG2972	Histidine kinase
GQS07_RS00540	COG3279	Response regulator of the LytR AlgR family
GQS07_RS00555	COG0747	negative chemotaxis
GQS07_RS00560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQS07_RS00610	COG0183	Belongs to the thiolase family
GQS07_RS00615	COG0791	NLP P60 protein
GQS07_RS00620	COG0513	Belongs to the DEAD box helicase family
GQS07_RS00625	COG2211	Major facilitator Superfamily
GQS07_RS00630	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GQS07_RS00635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GQS07_RS00660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQS07_RS00670	COG0799	negative regulation of ribosome biogenesis
GQS07_RS00675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS07_RS00685	COG4589	Belongs to the CDS family
GQS07_RS00690	COG0688	phosphatidylethanolamine metabolic process
GQS07_RS00705	COG0305	Participates in initiation and elongation during chromosome replication
GQS07_RS00710	COG0825	malonyl-CoA metabolic process
GQS07_RS00725	COG0343	queuine tRNA-ribosyltransferase activity
GQS07_RS00730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS07_RS00795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GQS07_RS00800	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GQS07_RS00810	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GQS07_RS00820	COG3958	Transketolase
GQS07_RS00825	COG3959	Transketolase, thiamine diphosphate binding domain
GQS07_RS00830	COG1120	ATPase activity
GQS07_RS00835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GQS07_RS00840	COG1187	pseudouridine synthase activity
GQS07_RS00850	COG2195	Cleaves the N-terminal amino acid of tripeptides
GQS07_RS00860	COG3853	Toxic anion resistance protein (TelA)
GQS07_RS00880	COG0697	spore germination
GQS07_RS00985	COG2824	Alkylphosphonate utilization operon protein PhnA
GQS07_RS00990	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GQS07_RS01010	COG0419	ATPase involved in DNA repair
GQS07_RS01015	COG0420	3'-5' exonuclease activity
GQS07_RS01020	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GQS07_RS01030	COG2807	transmembrane transport
GQS07_RS01065	COG1611	Belongs to the LOG family
GQS07_RS01080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQS07_RS01115	COG1482	cell wall glycoprotein biosynthetic process
GQS07_RS01125	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GQS07_RS01135	COG0514	ATP-dependent DNA helicase (RecQ)
GQS07_RS01140	COG0517	IMP dehydrogenase activity
GQS07_RS01140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GQS07_RS01145	COG0805	protein transport
GQS07_RS01150	COG1137	ATPase activity
GQS07_RS01170	COG0497	DNA recombination
GQS07_RS01195	COG1528	Iron-storage protein
GQS07_RS01200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQS07_RS01210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQS07_RS01225	COG0359	binds to the 23S rRNA
GQS07_RS01230	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GQS07_RS01235	COG0360	Binds together with S18 to 16S ribosomal RNA
GQS07_RS01245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GQS07_RS01275	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GQS07_RS01285	COG0492	ferredoxin-NADP+ reductase activity
GQS07_RS01295	COG0814	amino acid
GQS07_RS01300	COG0814	amino acid
GQS07_RS01305	COG2910	NAD(P)H-binding
GQS07_RS01310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GQS07_RS01320	COG0525	valine-tRNA ligase activity
GQS07_RS01350	COG2814	Major facilitator Superfamily
GQS07_RS01360	COG2814	Major facilitator Superfamily
GQS07_RS01365	COG1253	flavin adenine dinucleotide binding
GQS07_RS01370	COG0295	cytidine deaminase activity
GQS07_RS01380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQS07_RS01385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GQS07_RS01405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GQS07_RS01410	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GQS07_RS01420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GQS07_RS01425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GQS07_RS01430	COG1216	Glycosyl transferase, family 2
GQS07_RS01435	COG1595	DNA-templated transcription, initiation
GQS07_RS01450	COG1999	signal sequence binding
GQS07_RS01465	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GQS07_RS01475	COG1959	2 iron, 2 sulfur cluster binding
GQS07_RS01490	COG0552	protein localization to endoplasmic reticulum
GQS07_RS01500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQS07_RS01505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GQS07_RS01510	COG1058	Belongs to the CinA family
GQS07_RS01510	COG1546	Belongs to the CinA family
GQS07_RS01520	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQS07_RS01525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQS07_RS01530	COG1858	cytochrome C peroxidase
GQS07_RS01560	COG1733	regulation of RNA biosynthetic process
GQS07_RS01580	COG1690	Belongs to the RtcB family
GQS07_RS01620	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS07_RS01630	COG0268	Binds directly to 16S ribosomal RNA
GQS07_RS01665	COG0442	prolyl-tRNA aminoacylation
GQS07_RS01685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQS07_RS01690	COG0584	glycerophosphoryl diester phosphodiesterase
GQS07_RS01695	COG0471	metal ion transport
GQS07_RS01705	COG2205	protein histidine kinase activity
GQS07_RS01725	COG0242	peptide deformylase activity
GQS07_RS01765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQS07_RS01770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GQS07_RS01800	COG0148	phosphopyruvate hydratase activity
GQS07_RS01805	COG0505	Belongs to the CarA family
GQS07_RS01810	COG0203	ribosomal protein L17
GQS07_RS01815	COG0202	RNA polymerase activity
GQS07_RS01820	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GQS07_RS01825	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GQS07_RS01830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQS07_RS01835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GQS07_RS01840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GQS07_RS01850	COG0200	Binds to the 23S rRNA
GQS07_RS01855	COG1841	ribosomal large subunit assembly
GQS07_RS01860	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GQS07_RS01865	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GQS07_RS01870	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GQS07_RS01875	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GQS07_RS01880	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GQS07_RS01885	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GQS07_RS01890	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GQS07_RS01895	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GQS07_RS01900	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GQS07_RS01905	COG0255	Belongs to the universal ribosomal protein uL29 family
GQS07_RS01910	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GQS07_RS01915	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GQS07_RS01920	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GQS07_RS01925	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GQS07_RS01930	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQS07_RS01935	COG0089	rRNA binding
GQS07_RS01940	COG0088	Forms part of the polypeptide exit tunnel
GQS07_RS01945	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GQS07_RS01950	COG0051	transcription antitermination factor activity, RNA binding
GQS07_RS01955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQS07_RS01960	COG0049	tRNA binding
GQS07_RS01965	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GQS07_RS01970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQS07_RS01985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GQS07_RS01995	COG2003	Belongs to the UPF0758 family
GQS07_RS02005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQS07_RS02025	COG3591	Belongs to the peptidase S1B family
GQS07_RS02030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS07_RS02035	COG0563	adenylate kinase activity
GQS07_RS02045	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GQS07_RS02050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GQS07_RS02055	COG0339	signal peptide processing
GQS07_RS02100	COG0748	coenzyme F420 binding
GQS07_RS02120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQS07_RS02130	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS07_RS02130	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS07_RS02155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQS07_RS02170	COG2814	Major facilitator Superfamily
GQS07_RS02175	COG0697	spore germination
GQS07_RS02185	COG1442	glycosyl transferase family 8
GQS07_RS02185	COG1216	Glycosyl transferase, family 2
GQS07_RS02190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GQS07_RS02195	COG1127	ABC transporter
GQS07_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
GQS07_RS02220	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS07_RS02225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQS07_RS02230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GQS07_RS02245	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQS07_RS02250	COG0085	RNA polymerase activity
GQS07_RS02255	COG0222	ribosome binding
GQS07_RS02260	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GQS07_RS02265	COG0081	regulation of translation
GQS07_RS02270	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GQS07_RS02315	COG4974	Belongs to the 'phage' integrase family
GQS07_RS02320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GQS07_RS02325	COG3279	Response regulator of the LytR AlgR family
GQS07_RS02360	COG1960	acyl-CoA dehydrogenase activity
GQS07_RS02395	COG4206	TonB-dependent receptor
GQS07_RS02395	COG1629	transport
GQS07_RS02415	COG4206	TonB-dependent receptor
GQS07_RS02415	COG1629	transport
GQS07_RS02420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GQS07_RS02425	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GQS07_RS02430	COG3951	Flagellar rod assembly protein muramidase FlgJ
GQS07_RS02430	COG1705	Flagellar rod assembly protein muramidase FlgJ
GQS07_RS02435	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GQS07_RS02445	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GQS07_RS02460	COG3186	Phenylalanine-4-hydroxylase
GQS07_RS02475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS07_RS02480	COG0739	heme binding
GQS07_RS02510	COG1160	GTP binding
GQS07_RS02515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GQS07_RS02545	COG0488	(ABC) transporter
GQS07_RS02570	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQS07_RS02585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQS07_RS02610	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GQS07_RS02615	COG0459	protein refolding
GQS07_RS02620	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GQS07_RS02625	COG0321	lipoyl(octanoyl) transferase activity
GQS07_RS02630	COG0401	homolog of Blt101
GQS07_RS02635	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GQS07_RS02640	COG1858	cytochrome C peroxidase
GQS07_RS02665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQS07_RS02675	COG1185	polyribonucleotide nucleotidyltransferase activity
GQS07_RS02680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GQS07_RS02690	COG0517	IMP dehydrogenase activity
GQS07_RS02700	COG1610	YqeY-like protein
GQS07_RS02705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQS07_RS02720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQS07_RS02725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GQS07_RS02730	COG0772	Belongs to the SEDS family
GQS07_RS02735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GQS07_RS02740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQS07_RS02745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GQS07_RS02760	COG0275	rRNA processing
GQS07_RS02765	COG2001	Belongs to the MraZ family
GQS07_RS02775	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GQS07_RS02790	COG4206	TonB-dependent receptor
GQS07_RS02790	COG1629	transport
GQS07_RS02795	COG0357	Ribosomal RNA small subunit methyltransferase G
GQS07_RS02810	COG1741	Belongs to the pirin family
GQS07_RS02815	COG1187	pseudouridine synthase activity
GQS07_RS02860	COG2081	HI0933 family
GQS07_RS02875	COG3361	conserved protein (COG2071)
GQS07_RS02900	COG1506	peptidase
GQS07_RS02900	COG0823	Involved in the tonB-independent uptake of proteins
GQS07_RS02905	COG3104	oligopeptide transport
GQS07_RS02910	COG3104	oligopeptide transport
GQS07_RS02915	COG3104	oligopeptide transport
GQS07_RS02920	COG3104	oligopeptide transport
GQS07_RS02930	COG2333	competence protein COMEC
GQS07_RS02930	COG0658	competence protein
GQS07_RS02935	COG0791	NLP P60 protein
GQS07_RS02950	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GQS07_RS02965	COG3757	hydrolase, family 25
GQS07_RS02970	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GQS07_RS02970	COG3264	Mechanosensitive ion channel
GQS07_RS03010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQS07_RS03015	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GQS07_RS03100	COG0228	four-way junction DNA binding
GQS07_RS03105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GQS07_RS03110	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GQS07_RS03120	COG0626	cystathionine gamma-synthase activity
GQS07_RS03125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GQS07_RS03130	COG0460	homoserine dehydrogenase
GQS07_RS03130	COG0527	aspartate kinase activity
GQS07_RS03145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GQS07_RS03160	COG0300	oxidoreductase activity
GQS07_RS03165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQS07_RS03185	COG1505	serine-type exopeptidase activity
GQS07_RS03210	COG0814	amino acid
GQS07_RS03240	COG2095	MarC family integral membrane protein
GQS07_RS03255	COG0084	hydrolase, TatD family'
GQS07_RS03265	COG0252	asparaginase activity
GQS07_RS03295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS07_RS03295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQS07_RS03305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GQS07_RS03310	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GQS07_RS03310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GQS07_RS03315	COG1765	OsmC-like protein
GQS07_RS03320	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GQS07_RS03330	COG1435	thymidine kinase activity
GQS07_RS03355	COG0720	synthase
GQS07_RS03360	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQS07_RS03370	COG0196	riboflavin kinase activity
GQS07_RS03385	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GQS07_RS03390	COG2251	uridine kinase activity
GQS07_RS03390	COG0195	Participates in both transcription termination and antitermination
GQS07_RS03395	COG0779	Required for maturation of 30S ribosomal subunits
GQS07_RS03425	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GQS07_RS03435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GQS07_RS03440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQS07_RS03445	COG0511	ligase activity, forming carbon-carbon bonds
GQS07_RS03450	COG0439	Biotin carboxylase
GQS07_RS03455	COG1278	Cold shock
GQS07_RS03460	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS07_RS03465	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS07_RS03475	COG0649	NAD binding
GQS07_RS03480	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GQS07_RS03485	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GQS07_RS03490	COG1034	ATP synthesis coupled electron transport
GQS07_RS03495	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQS07_RS03500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS07_RS03505	COG0839	Belongs to the complex I subunit 6 family
GQS07_RS03510	COG0713	ATP synthesis coupled electron transport
GQS07_RS03515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQS07_RS03520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS07_RS03525	COG1007	ATP synthesis coupled electron transport
GQS07_RS03530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQS07_RS03535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQS07_RS03540	COG0512	Glutamine amidotransferase of anthranilate synthase
GQS07_RS03545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GQS07_RS03550	COG0134	indole-3-glycerol-phosphate synthase activity
GQS07_RS03555	COG0135	phosphoribosylanthranilate isomerase activity
GQS07_RS03560	COG0133	tryptophan synthase activity
GQS07_RS03565	COG0159	tryptophan synthase activity
GQS07_RS03580	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GQS07_RS03580	COG1918	ferrous iron import across plasma membrane
GQS07_RS03585	COG1999	signal sequence binding
GQS07_RS03590	COG3590	peptidase
GQS07_RS03595	COG0793	Belongs to the peptidase S41A family
GQS07_RS03610	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GQS07_RS03620	COG0527	aspartate kinase activity
GQS07_RS03665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS07_RS03665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS07_RS03670	COG0667	Aldo Keto reductase
GQS07_RS03680	COG0166	Belongs to the GPI family
GQS07_RS03685	COG0739	heme binding
GQS07_RS03690	COG3483	tryptophan 2,3-dioxygenase activity
GQS07_RS03700	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GQS07_RS03705	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GQS07_RS03710	COG1752	Esterase of the alpha-beta hydrolase superfamily
GQS07_RS03715	COG0322	excinuclease ABC activity
GQS07_RS03725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GQS07_RS03730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GQS07_RS03740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GQS07_RS03745	COG1381	Involved in DNA repair and RecF pathway recombination
GQS07_RS03765	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GQS07_RS03770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GQS07_RS03775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQS07_RS03785	COG0297	glycogen (starch) synthase activity
GQS07_RS03790	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GQS07_RS03795	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GQS07_RS03805	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GQS07_RS03820	COG1012	belongs to the aldehyde dehydrogenase family
GQS07_RS03825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQS07_RS03835	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GQS07_RS03840	COG0612	Peptidase, M16
GQS07_RS03875	COG2239	Acts as a magnesium transporter
GQS07_RS03880	COG1285	pathogenesis
GQS07_RS03885	COG5002	protein histidine kinase activity
GQS07_RS03895	COG0629	single-stranded DNA binding
GQS07_RS03900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQS07_RS03900	COG3153	acetyltransferase
GQS07_RS03940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GQS07_RS03945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GQS07_RS03960	COG1774	PSP1 C-terminal conserved region
GQS07_RS03965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GQS07_RS03995	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GQS07_RS04000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GQS07_RS04005	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQS07_RS04010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GQS07_RS04015	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQS07_RS04020	COG0356	it plays a direct role in the translocation of protons across the membrane
GQS07_RS04045	COG4152	abc transporter atp-binding protein
GQS07_RS04065	COG1621	beta-fructofuranosidase activity
GQS07_RS04075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GQS07_RS04080	COG1979	alcohol dehydrogenase
GQS07_RS04085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GQS07_RS04090	COG0194	GDP metabolic process
GQS07_RS04110	COG0826	peptidase U32
GQS07_RS04120	COG0242	peptide deformylase activity
GQS07_RS04125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GQS07_RS04140	COG0180	Tryptophanyl-tRNA synthetase
GQS07_RS04145	COG0758	DNA mediated transformation
GQS07_RS04145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQS07_RS04155	COG1607	acyl-coa hydrolase
GQS07_RS04170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQS07_RS04175	COG2502	aspartate--ammonia ligase
GQS07_RS04190	COG2151	metal-sulfur cluster biosynthetic enzyme
GQS07_RS04195	COG2166	iron-sulfur cluster assembly
GQS07_RS04200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQS07_RS04210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS07_RS04215	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GQS07_RS04220	COG3720	iron ion transport
GQS07_RS04230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQS07_RS04235	COG0719	Fe-S assembly protein
GQS07_RS04240	COG0396	ATPase activity
GQS07_RS04245	COG0719	Fe-S assembly protein
GQS07_RS04250	COG0316	Belongs to the HesB IscA family
GQS07_RS04255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS07_RS04270	COG0594	ribonuclease P activity
GQS07_RS04275	COG2365	Tyrosine phosphatase family
GQS07_RS04285	COG1388	LysM domain
GQS07_RS04285	COG3942	CHAP domain
GQS07_RS04290	COG0126	phosphoglycerate kinase activity
GQS07_RS04295	COG0470	DNA polymerase III
GQS07_RS04300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GQS07_RS04315	COG0445	tRNA wobble uridine modification
GQS07_RS04320	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GQS07_RS04325	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GQS07_RS04325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQS07_RS04380	COG0557	exoribonuclease II activity
GQS07_RS04385	COG0318	PFAM AMP-dependent synthetase and ligase
GQS07_RS04390	COG0698	ribose 5-phosphate isomerase
GQS07_RS04400	COG2183	response to ionizing radiation
GQS07_RS04405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQS07_RS04430	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GQS07_RS04445	COG1216	Glycosyl transferase, family 2
GQS07_RS04465	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GQS07_RS04470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQS07_RS04480	COG0151	Belongs to the GarS family
GQS07_RS04495	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GQS07_RS04510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GQS07_RS04525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GQS07_RS04540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQS07_RS04550	COG0165	Argininosuccinate lyase
GQS07_RS04555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GQS07_RS04565	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GQS07_RS04595	COG2304	oxidoreductase activity
GQS07_RS04600	COG2304	oxidoreductase activity
GQS07_RS04615	COG0714	Associated with various cellular activities
GQS07_RS04625	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GQS07_RS04635	COG1012	belongs to the aldehyde dehydrogenase family
GQS07_RS04655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GQS07_RS04660	COG0756	dUTP diphosphatase activity
GQS07_RS04670	COG1722	exodeoxyribonuclease VII activity
GQS07_RS04675	COG0668	transmembrane transport
GQS07_RS04680	COG1360	Flagellar Motor Protein
GQS07_RS04685	COG0708	Exodeoxyribonuclease III
GQS07_RS04695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQS07_RS04700	COG2239	Acts as a magnesium transporter
GQS07_RS04705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GQS07_RS04715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQS07_RS04840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQS07_RS04845	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GQS07_RS04850	COG0193	aminoacyl-tRNA hydrolase activity
GQS07_RS04855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GQS07_RS04860	COG2814	Major facilitator Superfamily
GQS07_RS04865	COG1902	pentaerythritol trinitrate reductase activity
GQS07_RS04875	COG4771	TonB-dependent receptor
GQS07_RS04895	COG1131	(ABC) transporter
GQS07_RS04935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GQS07_RS04940	COG1619	proteins homologs of microcin C7 resistance protein MccF
GQS07_RS04945	COG0792	nuclease activity
GQS07_RS04950	COG4774	siderophore transport
GQS07_RS04975	COG1418	mRNA catabolic process
GQS07_RS04980	COG0471	metal ion transport
GQS07_RS04995	COG0328	RNA-DNA hybrid ribonuclease activity
GQS07_RS05005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQS07_RS05010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQS07_RS05015	COG0571	ribonuclease III activity
GQS07_RS05025	COG0469	pyruvate kinase activity
GQS07_RS05035	COG1074	ATP-dependent DNA helicase activity
GQS07_RS05070	COG1053	succinate dehydrogenase
GQS07_RS05075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GQS07_RS05080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQS07_RS05090	COG1040	competence protein
GQS07_RS05105	COG1027	Aspartate ammonia-lyase
GQS07_RS05110	COG0702	epimerase
GQS07_RS05120	COG0423	glycine-tRNA ligase activity
GQS07_RS05130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQS07_RS05175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQS07_RS05180	COG0439	Biotin carboxylase
GQS07_RS05190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GQS07_RS05210	COG1024	Enoyl-CoA hydratase
GQS07_RS05215	COG5000	phosphorelay sensor kinase activity
GQS07_RS05225	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GQS07_RS05235	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GQS07_RS05240	COG0181	hydroxymethylbilane synthase activity
GQS07_RS05250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GQS07_RS05260	COG0408	coproporphyrinogen oxidase activity
GQS07_RS05265	COG0113	porphobilinogen synthase activity
GQS07_RS05275	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GQS07_RS05275	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GQS07_RS05280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GQS07_RS05290	COG0358	DNA primase activity
GQS07_RS05300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GQS07_RS05335	COG0745	RESPONSE REGULATOR receiver
GQS07_RS05340	COG5002	protein histidine kinase activity
GQS07_RS05345	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GQS07_RS05360	COG4191	Histidine kinase
GQS07_RS05395	COG0577	efflux transmembrane transporter activity
GQS07_RS05405	COG0577	efflux transmembrane transporter activity
GQS07_RS05415	COG0489	protein tyrosine kinase activity
GQS07_RS05425	COG0492	ferredoxin-NADP+ reductase activity
GQS07_RS05435	COG0586	Pfam SNARE associated Golgi protein
GQS07_RS05440	COG1301	dicarboxylic acid transport
GQS07_RS05445	COG1506	peptidase
GQS07_RS05445	COG0823	Involved in the tonB-independent uptake of proteins
GQS07_RS05460	COG0668	transmembrane transport
GQS07_RS05470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQS07_RS05495	COG0481	GTPase activity
GQS07_RS05505	COG3118	belongs to the thioredoxin family
GQS07_RS05510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS07_RS05510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQS07_RS05540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GQS07_RS05545	COG1970	mechanosensitive ion channel activity
GQS07_RS05550	COG4206	TonB-dependent receptor
GQS07_RS05550	COG1629	transport
GQS07_RS05585	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GQS07_RS05600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQS07_RS05610	COG3852	Histidine kinase
GQS07_RS05615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GQS07_RS05625	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GQS07_RS05630	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GQS07_RS05640	COG2022	thiamine diphosphate biosynthetic process
GQS07_RS05645	COG0352	thiamine-phosphate diphosphorylase activity
GQS07_RS05665	COG2104	thiamine diphosphate biosynthetic process
GQS07_RS05670	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GQS07_RS05675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GQS07_RS05680	COG0052	Belongs to the universal ribosomal protein uS2 family
GQS07_RS05685	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GQS07_RS05690	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQS07_RS05710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQS07_RS05710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQS07_RS05720	COG3118	belongs to the thioredoxin family
GQS07_RS05725	COG0726	polysaccharide deacetylase
GQS07_RS05730	COG1538	Outer membrane efflux protein
GQS07_RS05740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS07_RS05785	COG3340	Belongs to the peptidase S51 family
GQS07_RS05795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQS07_RS05800	COG0671	phosphoesterase, PA-phosphatase related
GQS07_RS05840	COG2363	Small membrane protein
GQS07_RS05845	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GQS07_RS05860	COG0463	Glycosyl transferase, family 2
GQS07_RS05865	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQS07_RS05880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GQS07_RS05890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GQS07_RS05895	COG1012	belongs to the aldehyde dehydrogenase family
GQS07_RS05900	COG2967	ApaG domain
GQS07_RS05910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQS07_RS05925	COG0427	acetyl-CoA hydrolase
GQS07_RS05930	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GQS07_RS05940	COG2989	Protein conserved in bacteria
GQS07_RS05945	COG4771	TonB-dependent receptor
GQS07_RS05955	COG4221	oxidoreductase activity
GQS07_RS05970	COG0754	glutathionylspermidine amidase activity
GQS07_RS06040	COG2003	Belongs to the UPF0758 family
GQS07_RS06075	COG0358	DNA primase activity
GQS07_RS06105	COG0346	lactoylglutathione lyase activity
GQS07_RS06110	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GQS07_RS06115	COG4591	ABC-type transport system involved in lipoprotein release permease component
GQS07_RS06125	COG0326	Molecular chaperone. Has ATPase activity
GQS07_RS06150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQS07_RS06155	COG0556	nucleotide-excision repair
GQS07_RS06175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQS07_RS06205	COG0142	geranyltranstransferase activity
GQS07_RS06225	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS07_RS06245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS07_RS06250	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GQS07_RS06260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GQS07_RS06265	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GQS07_RS06270	COG0612	Peptidase, M16
GQS07_RS06275	COG0612	Peptidase, M16
GQS07_RS06290	COG0629	single-stranded DNA binding
GQS07_RS06300	COG0776	regulation of translation
GQS07_RS06305	COG1530	ribonuclease E activity
GQS07_RS06310	COG4953	penicillin-binding protein 1C
GQS07_RS06315	COG2373	Large extracellular alpha-helical protein
GQS07_RS06325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GQS07_RS06340	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GQS07_RS06345	COG0017	Asparaginyl-tRNA synthetase
GQS07_RS06350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GQS07_RS06355	COG0233	cytoplasmic translational termination
GQS07_RS06360	COG0528	UMP kinase activity
GQS07_RS06385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GQS07_RS06390	COG1968	undecaprenyl-diphosphatase activity
GQS07_RS06400	COG2177	Part of the ABC transporter FtsEX involved in
GQS07_RS06405	COG0495	leucyl-tRNA aminoacylation
GQS07_RS06430	COG0437	4 iron, 4 sulfur cluster binding
GQS07_RS06455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GQS07_RS06460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQS07_RS06465	COG2255	four-way junction helicase activity
GQS07_RS06470	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GQS07_RS06475	COG0281	malic enzyme
GQS07_RS06475	COG0280	phosphate acetyltransferase
GQS07_RS06480	COG0632	four-way junction helicase activity
GQS07_RS06490	COG0509	glycine decarboxylation via glycine cleavage system
GQS07_RS06500	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GQS07_RS06505	COG0109	protoheme IX farnesyltransferase activity
GQS07_RS06510	COG1845	cytochrome c oxidase, subunit III
GQS07_RS06515	COG1845	cytochrome c oxidase, subunit III
GQS07_RS06530	COG1999	signal sequence binding
GQS07_RS06535	COG2322	membrane
GQS07_RS06550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS07_RS06555	COG1214	PFAM Peptidase M22, glycoprotease
GQS07_RS06560	COG0668	transmembrane transport
GQS07_RS06565	COG1331	Highly conserved protein containing a thioredoxin domain
GQS07_RS06575	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GQS07_RS06590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GQS07_RS06595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GQS07_RS06615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQS07_RS06625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQS07_RS06635	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GQS07_RS06655	COG1950	PFAM Membrane protein of
GQS07_RS06660	COG0544	peptidyl-prolyl cis-trans isomerase activity
GQS07_RS06670	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GQS07_RS06715	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GQS07_RS06730	COG1428	Deoxynucleoside kinase
GQS07_RS06735	COG0616	signal peptide processing
GQS07_RS06760	COG4717	serine-type aminopeptidase activity
GQS07_RS06765	COG0656	L-ascorbic acid biosynthetic process
GQS07_RS06780	COG2814	Major facilitator Superfamily
GQS07_RS06785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GQS07_RS06810	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GQS07_RS06835	COG0772	Belongs to the SEDS family
GQS07_RS06840	COG0768	penicillin binding
GQS07_RS06855	COG1077	Cell shape determining protein MreB Mrl
GQS07_RS06860	COG0138	bifunctional purine biosynthesis protein purh
GQS07_RS06870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GQS07_RS06895	COG2226	methyltransferase
GQS07_RS06905	COG1115	amino acid carrier protein
GQS07_RS06910	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GQS07_RS06920	COG0022	dehydrogenase e1 component
GQS07_RS06920	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS07_RS06935	COG2086	electron transfer activity
GQS07_RS06940	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GQS07_RS06950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GQS07_RS06960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GQS07_RS06970	COG1428	Deoxynucleoside kinase
GQS07_RS06975	COG1131	(ABC) transporter
GQS07_RS06985	COG0730	response to heat
GQS07_RS06990	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GQS07_RS06995	COG1162	GTPase activity
GQS07_RS07005	COG0612	Peptidase, M16
GQS07_RS07020	COG1629	transport
GQS07_RS07020	COG4206	TonB-dependent receptor
GQS07_RS07025	COG1490	D-aminoacyl-tRNA deacylase activity
GQS07_RS07045	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GQS07_RS07050	COG3844	kynureninase activity
GQS07_RS07055	COG0010	Belongs to the arginase family
GQS07_RS07060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQS07_RS07065	COG0433	COG0433 Predicted ATPase
GQS07_RS07070	COG0811	peptide transport
GQS07_RS07105	COG0602	queuosine metabolic process
GQS07_RS07140	COG4206	TonB-dependent receptor
GQS07_RS07140	COG1629	transport
GQS07_RS07155	COG3876	Protein conserved in bacteria
GQS07_RS07190	COG0545	Peptidyl-prolyl cis-trans isomerase
GQS07_RS07200	COG1114	Component of the transport system for branched-chain amino acids
GQS07_RS07210	COG1027	Aspartate ammonia-lyase
GQS07_RS07215	COG0252	asparaginase activity
GQS07_RS07220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GQS07_RS07265	COG2217	Heavy metal translocating P-type atpase
GQS07_RS07275	COG3047	cAMP biosynthetic process
GQS07_RS07290	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GQS07_RS07300	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GQS07_RS07305	COG2949	membrane
GQS07_RS07310	COG0513	Belongs to the DEAD box helicase family
GQS07_RS07315	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS07_RS07315	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS07_RS07320	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS07_RS07340	COG0527	aspartate kinase activity
GQS07_RS07345	COG0019	diaminopimelate decarboxylase activity
GQS07_RS07365	COG2264	protein methyltransferase activity
GQS07_RS07385	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQS07_RS07395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GQS07_RS07400	COG1181	Belongs to the D-alanine--D-alanine ligase family
GQS07_RS07410	COG0564	pseudouridine synthase activity
GQS07_RS07415	COG0037	tRNA processing
GQS07_RS07440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQS07_RS07445	COG1132	(ABC) transporter
GQS07_RS07450	COG0101	tRNA pseudouridine synthase activity
GQS07_RS07495	COG1136	(ABC) transporter
GQS07_RS07500	COG2096	Adenosyltransferase
GQS07_RS07510	COG0653	protein targeting
GQS07_RS07520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQS07_RS07530	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GQS07_RS07535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQS07_RS07540	COG2217	Heavy metal translocating P-type atpase
GQS07_RS07550	COG3278	Belongs to the heme-copper respiratory oxidase family
GQS07_RS07565	COG0348	domain, Protein
GQS07_RS07585	COG0681	Belongs to the peptidase S26 family
GQS07_RS07590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GQS07_RS07600	COG1475	DNA binding
GQS07_RS07605	COG1192	Involved in chromosome partitioning
GQS07_RS07610	COG1028	Short-chain dehydrogenase reductase Sdr
GQS07_RS07620	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GQS07_RS07660	COG0753	catalase activity
GQS07_RS07675	COG0326	Molecular chaperone. Has ATPase activity
GQS07_RS07695	COG1695	Transcriptional regulator
GQS07_RS07705	COG1090	epimerase
GQS07_RS07710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GQS07_RS07715	COG0484	heat shock protein binding
GQS07_RS07720	COG4152	abc transporter atp-binding protein
GQS07_RS07730	COG2204	response regulator
GQS07_RS07755	COG0484	heat shock protein binding
GQS07_RS07780	COG1678	Uncharacterized ACR, COG1678
GQS07_RS07790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GQS07_RS07795	COG0514	ATP-dependent DNA helicase (RecQ)
GQS07_RS07815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQS07_RS07825	COG2801	Transposase and inactivated derivatives
GQS07_RS07835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GQS07_RS07845	COG4974	Belongs to the 'phage' integrase family
GQS07_RS07850	COG1418	mRNA catabolic process
GQS07_RS07870	COG0739	heme binding
GQS07_RS07890	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GQS07_RS07910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GQS07_RS07925	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GQS07_RS07945	COG3177	Filamentation induced by cAMP protein fic
GQS07_RS07950	COG1131	(ABC) transporter
GQS07_RS07960	COG0335	large ribosomal subunit rRNA binding
GQS07_RS07965	COG0336	Belongs to the RNA methyltransferase TrmD family
GQS07_RS07975	COG2814	Major facilitator Superfamily
GQS07_RS07980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQS07_RS07990	COG0697	spore germination
GQS07_RS07995	COG0069	glutamate synthase activity
GQS07_RS08000	COG0038	chloride channel
GQS07_RS08010	COG1132	(ABC) transporter
GQS07_RS08015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQS07_RS08025	COG1862	Preprotein translocase
GQS07_RS08030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQS07_RS08035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GQS07_RS08040	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GQS07_RS08045	COG0488	(ABC) transporter
GQS07_RS08055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS07_RS08075	COG2326	polyphosphate kinase activity
GQS07_RS08085	COG0534	Mate efflux family protein
GQS07_RS08100	COG2223	nitrite transmembrane transporter activity
GQS07_RS08110	COG2239	Acts as a magnesium transporter
GQS07_RS08120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQS07_RS08125	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GQS07_RS08145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQS07_RS08155	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GQS07_RS08160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQS07_RS08190	COG0564	pseudouridine synthase activity
GQS07_RS08195	COG0577	efflux transmembrane transporter activity
GQS07_RS08200	COG0124	histidyl-tRNA synthetase
GQS07_RS08225	COG2733	membrane
GQS07_RS08230	COG0564	pseudouridine synthase activity
GQS07_RS08235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GQS07_RS08240	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GQS07_RS08245	COG1943	Transposase
GQS07_RS08260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GQS07_RS08270	COG1663	tetraacyldisaccharide 4'-kinase activity
GQS07_RS08275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GQS07_RS08290	COG1187	pseudouridine synthase activity
GQS07_RS08325	COG3842	ATPase activity
GQS07_RS08330	COG1506	peptidase
GQS07_RS08335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQS07_RS08340	COG2356	endonuclease I
GQS07_RS08345	COG2356	endonuclease I
GQS07_RS08350	COG2356	endonuclease I
GQS07_RS08355	COG2356	endonuclease I
GQS07_RS08360	COG2356	endonuclease I
GQS07_RS08365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQS07_RS08365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQS07_RS08380	COG1595	DNA-templated transcription, initiation
GQS07_RS08385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQS07_RS08400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GQS07_RS08410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQS07_RS08415	COG1049	propionate catabolic process, 2-methylcitrate cycle
GQS07_RS08435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQS07_RS08445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQS07_RS08450	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GQS07_RS08460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GQS07_RS08475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS07_RS08480	COG0606	chelatase, subunit chli
GQS07_RS08490	COG2321	neutral zinc metallopeptidase
GQS07_RS08495	COG0217	transcriptional regulatory protein
GQS07_RS08500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQS07_RS08520	COG2217	Heavy metal translocating P-type atpase
GQS07_RS08535	COG0564	pseudouridine synthase activity
GQS07_RS08540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GQS07_RS08550	COG1760	l-serine dehydratase
GQS07_RS08555	COG3586	endonuclease activity
GQS07_RS08580	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GQS07_RS08650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GQS07_RS08685	COG0358	DNA primase activity
GQS07_RS08685	COG0305	Participates in initiation and elongation during chromosome replication
GQS07_RS08710	COG2259	Doxx family
GQS07_RS08730	COG0484	heat shock protein binding
GQS07_RS08775	COG1846	Transcriptional regulator
GQS07_RS08825	COG4974	Belongs to the 'phage' integrase family
GQS07_RS08840	COG0443	Heat shock 70 kDa protein
GQS07_RS08895	COG2204	response regulator
GQS07_RS08905	COG0823	Involved in the tonB-independent uptake of proteins
GQS07_RS08905	COG1506	peptidase
GQS07_RS08915	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GQS07_RS08930	COG0456	acetyltransferase
GQS07_RS08955	COG0116	Belongs to the methyltransferase superfamily
GQS07_RS08975	COG0436	Aminotransferase
GQS07_RS08980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQS07_RS08980	COG1333	cytochrome c biogenesis protein
GQS07_RS09000	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GQS07_RS09010	COG0861	Integral membrane protein TerC family
GQS07_RS09025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GQS07_RS09035	COG0742	ribosomal rna small subunit methyltransferase
GQS07_RS09045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GQS07_RS09050	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GQS07_RS09105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GQS07_RS09110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS07_RS09120	COG0167	dihydroorotate dehydrogenase activity
GQS07_RS09125	COG1280	lysine exporter protein (LysE YggA)
GQS07_RS09135	COG0516	GMP reductase activity
GQS07_RS09135	COG0517	IMP dehydrogenase activity
GQS07_RS09150	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GQS07_RS09160	COG1045	serine acetyltransferase
GQS07_RS09165	COG2801	Transposase and inactivated derivatives
GQS07_RS09185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQS07_RS09210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQS07_RS09215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQS07_RS09220	COG0512	Glutamine amidotransferase of anthranilate synthase
GQS07_RS09225	COG0477	Major facilitator Superfamily
GQS07_RS09240	COG1053	succinate dehydrogenase
GQS07_RS09245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GQS07_RS09255	COG0471	metal ion transport
GQS07_RS09260	COG0415	Belongs to the DNA photolyase family
GQS07_RS09290	COG2365	Tyrosine phosphatase family
GQS07_RS09315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQS07_RS09330	COG0156	8-amino-7-oxononanoate synthase activity
GQS07_RS09340	COG2076	Multidrug Resistance protein
GQS07_RS09345	COG1741	Belongs to the pirin family
GQS07_RS09520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GQS07_RS09525	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GQS07_RS09530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQS07_RS09535	COG0131	Imidazoleglycerol-phosphate dehydratase
GQS07_RS09535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GQS07_RS09540	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GQS07_RS09545	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GQS07_RS09550	COG0107	imidazoleglycerol-phosphate synthase activity
GQS07_RS09555	COG0140	phosphoribosyl-ATP diphosphatase activity
GQS07_RS09555	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GQS07_RS09570	COG0745	RESPONSE REGULATOR receiver
GQS07_RS09570	COG2972	Histidine kinase
GQS07_RS09575	COG3279	Response regulator of the LytR AlgR family
GQS07_RS09630	COG1518	maintenance of DNA repeat elements
GQS07_RS09635	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GQS07_RS09665	COG2814	Major facilitator Superfamily
GQS07_RS09675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GQS07_RS09695	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GQS07_RS09715	COG0831	urea catabolic process
GQS07_RS09720	COG0832	Belongs to the urease beta subunit family
GQS07_RS09725	COG0804	urea catabolic process
GQS07_RS09730	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GQS07_RS09740	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GQS07_RS09745	COG0829	nickel cation binding
GQS07_RS09750	COG4413	Urea transporter
GQS07_RS09760	COG0006	proline dipeptidase activity
GQS07_RS09780	COG2197	response regulator
GQS07_RS09795	COG0823	Involved in the tonB-independent uptake of proteins
GQS07_RS09795	COG4946	Tricorn protease homolog
GQS07_RS09795	COG1506	peptidase
GQS07_RS09805	COG4206	TonB-dependent receptor
GQS07_RS09805	COG1629	transport
GQS07_RS09830	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GQS07_RS09835	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GQS07_RS09840	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GQS07_RS09875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GQS07_RS09885	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GQS07_RS09890	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQS07_RS09895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GQS07_RS09915	COG0363	glucosamine-6-phosphate deaminase activity
GQS07_RS09975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GQS07_RS09980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GQS07_RS09990	COG0205	6-phosphofructokinase activity
GQS07_RS09995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQS07_RS10010	COG0251	oxidation-reduction process
GQS07_RS10020	COG0860	N-Acetylmuramoyl-L-alanine amidase
GQS07_RS10025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GQS07_RS10035	COG2181	nitrate reductase activity
GQS07_RS10035	COG0247	lactate metabolic process
GQS07_RS10045	COG1472	Belongs to the glycosyl hydrolase 3 family
GQS07_RS10065	COG0438	transferase activity, transferring glycosyl groups
GQS07_RS10080	COG0659	secondary active sulfate transmembrane transporter activity
GQS07_RS10085	COG2207	Transcriptional regulator
GQS07_RS10090	COG0402	S-adenosylhomocysteine deaminase activity
GQS07_RS10100	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GQS07_RS10105	COG0386	Belongs to the glutathione peroxidase family
GQS07_RS10110	COG1605	Chorismate mutase
GQS07_RS10110	COG0077	Prephenate dehydratase
GQS07_RS10135	COG0540	Belongs to the ATCase OTCase family
GQS07_RS10145	COG1234	tRNA 3'-trailer cleavage
GQS07_RS10150	COG0259	pyridoxamine-phosphate oxidase activity
GQS07_RS10205	COG0471	metal ion transport
GQS07_RS10210	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GQS07_RS10245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQS07_RS10265	COG1397	ADP-ribosylglycohydrolase
GQS07_RS10340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GQS07_RS10345	COG0579	oxidoreductase
GQS07_RS10350	COG4585	Histidine kinase
GQS07_RS10375	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GQS07_RS10380	COG5002	protein histidine kinase activity
GQS07_RS10380	COG3850	Histidine kinase
GQS07_RS10385	COG0745	RESPONSE REGULATOR receiver
GQS07_RS10395	COG1228	amidohydrolase
GQS07_RS10400	COG0598	Magnesium transport protein CorA
GQS07_RS10445	COG4753	response regulator
GQS07_RS10445	COG2207	Transcriptional regulator
GQS07_RS10465	COG1309	transcriptional regulator
GQS07_RS10475	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GQS07_RS10475	COG2885	chlorophyll binding
GQS07_RS10490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQS07_RS10495	COG3457	Alanine racemase
GQS07_RS10510	COG0116	Belongs to the methyltransferase superfamily
GQS07_RS10510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQS07_RS10525	COG1522	sequence-specific DNA binding
GQS07_RS10535	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GQS07_RS10590	COG0006	proline dipeptidase activity
GQS07_RS10600	COG1703	isobutyryl-CoA mutase activity
GQS07_RS10600	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS07_RS10600	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS07_RS10630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS07_RS10645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GQS07_RS10655	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GQS07_RS10660	COG1166	arginine decarboxylase activity
GQS07_RS10675	COG0012	GTP binding
GQS07_RS10695	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GQS07_RS10705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQS07_RS10730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQS07_RS10740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GQS07_RS10755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQS07_RS10795	COG0494	nUDIX hydrolase
GQS07_RS10805	COG1132	(ABC) transporter
GQS07_RS10810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQS07_RS10830	COG1028	Short-chain dehydrogenase reductase Sdr
GQS07_RS10840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS07_RS10870	COG1620	l-lactate permease
GQS07_RS10875	COG0247	lactate metabolic process
GQS07_RS10895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQS07_RS10925	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GQS07_RS10940	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GQS07_RS10945	COG0248	Ppx GppA phosphatase
GQS07_RS10955	COG1136	(ABC) transporter
GQS07_RS10960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQS07_RS10995	COG3275	phosphorelay sensor kinase activity
GQS07_RS11005	COG3279	Response regulator of the LytR AlgR family
GQS07_RS11010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQS07_RS11015	COG1611	Belongs to the LOG family
GQS07_RS11035	COG2252	PERMEase
GQS07_RS11065	COG0617	tRNA 3'-terminal CCA addition
GQS07_RS11070	COG0009	L-threonylcarbamoyladenylate synthase
GQS07_RS11085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GQS07_RS11115	COG2234	aminopeptidase activity
GQS07_RS11120	COG0300	oxidoreductase activity
GQS07_RS11125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GQS07_RS11130	COG1024	Enoyl-CoA hydratase
GQS07_RS11145	COG3279	Response regulator of the LytR AlgR family
GQS07_RS11160	COG2195	Cleaves the N-terminal amino acid of tripeptides
GQS07_RS11170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GQS07_RS11175	COG0284	orotidine-5'-phosphate decarboxylase activity
GQS07_RS11180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GQS07_RS11195	COG0210	DNA helicase
GQS07_RS11200	COG0009	L-threonylcarbamoyladenylate synthase
GQS07_RS11205	COG0045	succinate-CoA ligase (ADP-forming) activity
GQS07_RS11215	COG0556	nucleotide-excision repair
GQS07_RS11225	COG0494	nUDIX hydrolase
GQS07_RS11230	COG2814	Major facilitator Superfamily
GQS07_RS11240	COG1960	acyl-CoA dehydrogenase activity
GQS07_RS11245	COG0183	Belongs to the thiolase family
GQS07_RS11250	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQS07_RS11250	COG1024	Enoyl-CoA hydratase
GQS07_RS11255	COG1846	Transcriptional regulator
GQS07_RS11260	COG1022	Amp-dependent synthetase and ligase
GQS07_RS11295	COG0542	response to heat
GQS07_RS11330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQS07_RS11340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GQS07_RS11345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQS07_RS11350	COG2176	DNA-directed DNA polymerase activity
GQS07_RS11355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GQS07_RS11365	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQS07_RS11370	COG0673	inositol 2-dehydrogenase activity
GQS07_RS11375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQS07_RS11380	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GQS07_RS11390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQS07_RS11400	COG1086	Polysaccharide biosynthesis protein
GQS07_RS11405	COG1335	isochorismatase
GQS07_RS11425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQS07_RS11425	COG0301	tRNA thio-modification
GQS07_RS11435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQS07_RS11455	COG0519	Catalyzes the synthesis of GMP from XMP
GQS07_RS11470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQS07_RS11475	COG0569	domain protein
GQS07_RS11480	COG3384	dioxygenase
GQS07_RS11490	COG2070	2-Nitropropane dioxygenase
GQS07_RS11515	COG1575	Belongs to the MenA family. Type 1 subfamily
GQS07_RS11520	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GQS07_RS11535	COG0697	spore germination
GQS07_RS11540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQS07_RS11550	COG0482	sulfurtransferase activity
GQS07_RS11560	COG0706	membrane insertase activity
GQS07_RS11565	COG0504	CTP synthase activity
GQS07_RS11570	COG0833	amino acid
GQS07_RS11575	COG1404	Belongs to the peptidase S8 family
GQS07_RS11580	COG3956	TIGRFAM MazG family protein
GQS07_RS11610	COG0242	peptide deformylase activity
GQS07_RS11650	COG2197	response regulator
GQS07_RS11705	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GQS07_RS11725	COG1917	Cupin 2, conserved barrel domain protein
GQS07_RS11725	COG4977	sequence-specific DNA binding
GQS07_RS11735	COG4628	conserved protein (DUF2132)
GQS07_RS11745	COG1028	Short-chain dehydrogenase reductase Sdr
GQS07_RS11750	COG0823	Involved in the tonB-independent uptake of proteins
GQS07_RS11750	COG1506	peptidase
GQS07_RS11765	COG3118	belongs to the thioredoxin family
GQS07_RS11795	COG1252	NADH dehydrogenase
GQS07_RS11800	COG3530	Putative quorum-sensing-regulated virulence factor
GQS07_RS11810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQS07_RS11810	COG0519	Catalyzes the synthesis of GMP from XMP
GQS07_RS11815	COG0786	glutamate:sodium symporter activity
GQS07_RS11820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS07_RS11825	COG0488	(ABC) transporter
GQS07_RS11855	COG1360	Flagellar Motor Protein
GQS07_RS11905	COG1702	phosphate starvation-inducible protein PhoH
GQS07_RS11915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GQS07_RS11930	COG0023	Translation Initiation Factor
GQS07_RS11935	COG0813	purine-nucleoside phosphorylase activity
GQS07_RS11940	COG0427	acetyl-CoA hydrolase
GQS07_RS11945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GQS07_RS11955	COG2363	Small membrane protein
GQS07_RS11960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQS07_RS11995	COG0237	dephospho-CoA kinase activity
GQS07_RS12000	COG1216	Glycosyl transferase, family 2
GQS07_RS12000	COG0463	Glycosyl transferase, family 2
GQS07_RS12005	COG2204	response regulator
GQS07_RS12030	COG1858	cytochrome C peroxidase
GQS07_RS12040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GQS07_RS12045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GQS07_RS12050	COG0513	Belongs to the DEAD box helicase family
GQS07_RS12085	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GQS07_RS12085	COG0321	lipoyl(octanoyl) transferase activity
GQS07_RS12095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQS07_RS12100	COG0697	spore germination
GQS07_RS12105	COG0427	acetyl-CoA hydrolase
GQS07_RS12110	COG1193	negative regulation of DNA recombination
GQS07_RS12115	COG3011	Protein conserved in bacteria
GQS07_RS12130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQS07_RS12135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GQS07_RS12140	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQS07_RS12145	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GQS07_RS12145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GQS07_RS12150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQS07_RS12155	COG1078	dGTPase activity
GQS07_RS12160	COG2986	histidine ammonia-lyase
GQS07_RS12165	COG3022	response to hydroperoxide
GQS07_RS12215	COG1566	PFAM secretion protein HlyD family protein
GQS07_RS12225	COG0730	response to heat
GQS07_RS12265	COG1061	Type III restriction enzyme res subunit
GQS07_RS12325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GQS07_RS12330	COG0083	homoserine kinase activity
GQS07_RS12335	COG0460	homoserine dehydrogenase
GQS07_RS12335	COG0527	aspartate kinase activity
GQS07_RS12350	COG2814	Major facilitator Superfamily
GQS07_RS12375	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQS07_RS12410	COG0513	Belongs to the DEAD box helicase family
GQS07_RS12415	COG1278	Cold shock
GQS07_RS12445	COG3059	membrane
GQS07_RS12450	COG2207	Transcriptional regulator
GQS07_RS12450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GQS07_RS12460	COG1607	acyl-coa hydrolase
GQS07_RS12470	COG0583	DNA-binding transcription factor activity
GQS07_RS12475	COG2814	Major facilitator Superfamily
GQS07_RS12500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQS07_RS12505	COG1368	sulfuric ester hydrolase activity
GQS07_RS12580	COG0471	metal ion transport
GQS07_RS12585	COG0517	IMP dehydrogenase activity
GQS07_RS12715	COG0358	DNA primase activity
GQS07_RS12735	COG4974	Belongs to the 'phage' integrase family
GQS07_RS12740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GQS07_RS12760	COG0302	gtp cyclohydrolase
GQS07_RS12765	COG0215	cysteine-tRNA ligase activity
GQS07_RS12770	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GQS07_RS12775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GQS07_RS12780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQS07_RS12790	COG0187	DNA topoisomerase II activity
GQS07_RS12810	COG1346	cytolysis
GQS07_RS12820	COG2884	Cell division ATP-binding protein ftsE
GQS07_RS12830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GQS07_RS12835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GQS07_RS12840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GQS07_RS12845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQS07_RS12880	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GQS07_RS12910	COG4974	Belongs to the 'phage' integrase family
GQS07_RS12950	COG0358	DNA primase activity
GQS07_RS12950	COG0305	Participates in initiation and elongation during chromosome replication
GQS07_RS12995	COG0513	Belongs to the DEAD box helicase family
GQS07_RS13030	COG0642	Histidine kinase
GQS07_RS13040	COG2996	Protein conserved in bacteria
GQS07_RS13050	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GQS07_RS13060	COG1363	Peptidase, m42
GQS07_RS13075	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GQS07_RS13090	COG0156	8-amino-7-oxononanoate synthase activity
GQS07_RS13095	COG0022	dehydrogenase e1 component
GQS07_RS13105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQS07_RS13140	COG1088	dTDP-glucose 4,6-dehydratase activity
GQS07_RS13145	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GQS07_RS13150	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GQS07_RS13155	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GQS07_RS13160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GQS07_RS13185	COG0745	RESPONSE REGULATOR receiver
GQS07_RS13200	COG0488	(ABC) transporter
GQS07_RS13220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GQS07_RS13225	COG0424	maF-like protein
GQS07_RS13240	COG2860	membrane
GQS07_RS13270	COG0714	Associated with various cellular activities
GQS07_RS13280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQS07_RS13295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQS07_RS13305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GQS07_RS13315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQS07_RS13325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GQS07_RS13340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GQS07_RS13345	COG0542	response to heat
GQS07_RS13350	COG4067	protein conserved in archaea
GQS07_RS13350	COG0189	ligase activity
GQS07_RS13360	COG0288	reversible hydration of carbon dioxide
GQS07_RS13370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GQS07_RS13435	COG0339	signal peptide processing
GQS07_RS13470	COG0405	Gamma-glutamyltransferase
GQS07_RS13525	COG2197	response regulator
GQS07_RS13560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQS07_RS13565	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GQS07_RS13575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GQS07_RS13600	COG0149	triose-phosphate isomerase activity
GQS07_RS13610	COG1012	belongs to the aldehyde dehydrogenase family
GQS07_RS13620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS07_RS13630	COG2890	protein-(glutamine-N5) methyltransferase activity
GQS07_RS13635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQS07_RS13635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQS07_RS13640	COG1739	Uncharacterized protein family UPF0029
GQS07_RS13655	COG0824	Thioesterase