locus-tag	class	description
BK054_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BK054_RS00010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BK054_RS00030	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BK054_RS00035	COG0306	phosphate transporter
BK054_RS00045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BK054_RS00055	COG2855	membrane
BK054_RS00060	COG0583	DNA-binding transcription factor activity
BK054_RS00085	COG2378	regulation of single-species biofilm formation
BK054_RS00130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BK054_RS00145	COG0587	DNA-directed DNA polymerase activity
BK054_RS00155	COG1396	sequence-specific DNA binding
BK054_RS00160	COG1063	alcohol dehydrogenase
BK054_RS00165	COG1484	DNA-dependent DNA replication
BK054_RS00170	COG4584	PFAM Integrase catalytic
BK054_RS00175	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BK054_RS00180	COG0582	viral genome integration into host DNA
BK054_RS00210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BK054_RS00215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK054_RS00225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BK054_RS00235	COG0659	secondary active sulfate transmembrane transporter activity
BK054_RS00270	COG2072	flavoprotein involved in K transport
BK054_RS00275	COG0798	PFAM Bile acid sodium symporter
BK054_RS00340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BK054_RS00340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BK054_RS00355	COG1674	ftsk spoiiie
BK054_RS00375	COG0450	alkyl hydroperoxide reductase
BK054_RS00380	COG1757	Na H antiporter
BK054_RS00385	COG3781	membrane
BK054_RS00400	COG0517	IMP dehydrogenase activity
BK054_RS00400	COG0516	GMP reductase activity
BK054_RS00410	COG0604	alcohol dehydrogenase
BK054_RS00415	COG1917	Cupin 2, conserved barrel domain protein
BK054_RS00415	COG4977	sequence-specific DNA binding
BK054_RS00425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BK054_RS00445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK054_RS00460	COG2171	N-acyltransferase activity
BK054_RS00465	COG1368	sulfuric ester hydrolase activity
BK054_RS00470	COG0463	Glycosyl transferase, family 2
BK054_RS00475	COG0463	Glycosyl transferase, family 2
BK054_RS00480	COG0047	phosphoribosylformylglycinamidine synthase activity
BK054_RS00480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BK054_RS00495	COG4260	virion core protein, lumpy skin disease virus
BK054_RS00510	COG1696	Membrane protein involved in D-alanine export
BK054_RS00515	COG3584	3D domain protein
BK054_RS00515	COG1388	LysM domain
BK054_RS00525	COG0018	arginyl-trna synthetase
BK054_RS00535	COG1881	PFAM PEBP family protein
BK054_RS00550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BK054_RS00565	COG3344	reverse transcriptase
BK054_RS00610	COG0285	dihydrofolate synthase activity
BK054_RS00625	COG0811	peptide transport
BK054_RS00630	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BK054_RS00635	COG1960	acyl-CoA dehydrogenase activity
BK054_RS00650	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BK054_RS00655	COG3047	cAMP biosynthetic process
BK054_RS00655	COG2885	chlorophyll binding
BK054_RS00670	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BK054_RS00670	COG2885	chlorophyll binding
BK054_RS00705	COG4753	response regulator
BK054_RS00705	COG2207	Transcriptional regulator
BK054_RS00755	COG0254	rRNA binding
BK054_RS00790	COG0463	Glycosyl transferase, family 2
BK054_RS00795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BK054_RS00800	COG1132	(ABC) transporter
BK054_RS00810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BK054_RS00815	COG0105	UTP biosynthetic process
BK054_RS00835	COG1393	Belongs to the ArsC family
BK054_RS00850	COG0133	tryptophan synthase activity
BK054_RS00860	COG0488	(ABC) transporter
BK054_RS00865	COG1408	metallophosphoesterase
BK054_RS00870	COG2972	Histidine kinase
BK054_RS00885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BK054_RS00945	COG0183	Belongs to the thiolase family
BK054_RS00950	COG0791	NLP P60 protein
BK054_RS00955	COG0513	Belongs to the DEAD box helicase family
BK054_RS00960	COG2211	Major facilitator Superfamily
BK054_RS00965	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BK054_RS00970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BK054_RS00995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BK054_RS01000	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BK054_RS01000	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BK054_RS01005	COG0799	negative regulation of ribosome biogenesis
BK054_RS01010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BK054_RS01020	COG4589	Belongs to the CDS family
BK054_RS01025	COG0688	phosphatidylethanolamine metabolic process
BK054_RS01035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BK054_RS01040	COG0305	Participates in initiation and elongation during chromosome replication
BK054_RS01045	COG0825	malonyl-CoA metabolic process
BK054_RS01060	COG0343	queuine tRNA-ribosyltransferase activity
BK054_RS01065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK054_RS01120	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BK054_RS01125	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BK054_RS01130	COG0500	methyltransferase
BK054_RS01135	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BK054_RS01145	COG3958	Transketolase
BK054_RS01150	COG3959	Transketolase, thiamine diphosphate binding domain
BK054_RS01170	COG1120	ATPase activity
BK054_RS01175	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BK054_RS01190	COG2195	Cleaves the N-terminal amino acid of tripeptides
BK054_RS01195	COG3853	Toxic anion resistance protein (TelA)
BK054_RS01215	COG0697	spore germination
BK054_RS01280	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BK054_RS01285	COG0252	asparaginase activity
BK054_RS01315	COG2824	Alkylphosphonate utilization operon protein PhnA
BK054_RS01320	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BK054_RS01355	COG0419	ATPase involved in DNA repair
BK054_RS01360	COG0420	3'-5' exonuclease activity
BK054_RS01375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BK054_RS01395	COG2807	transmembrane transport
BK054_RS01435	COG1611	Belongs to the LOG family
BK054_RS01450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BK054_RS01485	COG1482	cell wall glycoprotein biosynthetic process
BK054_RS01490	COG0720	synthase
BK054_RS01495	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BK054_RS01510	COG0514	ATP-dependent DNA helicase (RecQ)
BK054_RS01515	COG0517	IMP dehydrogenase activity
BK054_RS01515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BK054_RS01520	COG0805	protein transport
BK054_RS01525	COG1137	ATPase activity
BK054_RS01545	COG3279	Response regulator of the LytR AlgR family
BK054_RS01565	COG0497	DNA recombination
BK054_RS01590	COG1528	Iron-storage protein
BK054_RS01595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BK054_RS01605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BK054_RS01620	COG0359	binds to the 23S rRNA
BK054_RS01625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BK054_RS01630	COG0360	Binds together with S18 to 16S ribosomal RNA
BK054_RS01640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BK054_RS01685	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BK054_RS01695	COG0492	ferredoxin-NADP+ reductase activity
BK054_RS01705	COG0814	amino acid
BK054_RS01710	COG0814	amino acid
BK054_RS01715	COG2910	NAD(P)H-binding
BK054_RS01720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BK054_RS01730	COG0525	valine-tRNA ligase activity
BK054_RS01760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BK054_RS01765	COG2814	Major facilitator Superfamily
BK054_RS01770	COG1573	uracil-dna glycosylase
BK054_RS01780	COG2814	Major facilitator Superfamily
BK054_RS01790	COG1253	flavin adenine dinucleotide binding
BK054_RS01795	COG0295	cytidine deaminase activity
BK054_RS01805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BK054_RS01810	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BK054_RS01830	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BK054_RS01835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BK054_RS01845	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BK054_RS01850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BK054_RS01875	COG1999	signal sequence binding
BK054_RS01890	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BK054_RS01900	COG1959	2 iron, 2 sulfur cluster binding
BK054_RS01915	COG0552	protein localization to endoplasmic reticulum
BK054_RS01925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BK054_RS01930	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BK054_RS01935	COG1546	Belongs to the CinA family
BK054_RS01935	COG1058	Belongs to the CinA family
BK054_RS01945	COG0179	Fumarylacetoacetate (FAA) hydrolase
BK054_RS01955	COG1858	cytochrome C peroxidase
BK054_RS01990	COG1733	regulation of RNA biosynthetic process
BK054_RS02020	COG1131	(ABC) transporter
BK054_RS02080	COG3852	Histidine kinase
BK054_RS02125	COG1690	Belongs to the RtcB family
BK054_RS02140	COG3541	Predicted nucleotidyltransferase
BK054_RS02175	COG0508	dehydrogenase complex catalyzes the overall conversion of
BK054_RS02180	COG1217	gtp-binding protein TYPA
BK054_RS02185	COG0268	Binds directly to 16S ribosomal RNA
BK054_RS02220	COG0442	prolyl-tRNA aminoacylation
BK054_RS02240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BK054_RS02250	COG0471	metal ion transport
BK054_RS02265	COG2205	protein histidine kinase activity
BK054_RS02280	COG0242	peptide deformylase activity
BK054_RS02340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BK054_RS02345	COG0534	Mate efflux family protein
BK054_RS02370	COG4206	TonB-dependent receptor
BK054_RS02390	COG0148	phosphopyruvate hydratase activity
BK054_RS02395	COG0505	Belongs to the CarA family
BK054_RS02400	COG0203	ribosomal protein L17
BK054_RS02405	COG0202	RNA polymerase activity
BK054_RS02410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BK054_RS02415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BK054_RS02420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BK054_RS02425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BK054_RS02435	COG0200	Binds to the 23S rRNA
BK054_RS02440	COG1841	ribosomal large subunit assembly
BK054_RS02445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BK054_RS02450	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BK054_RS02455	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BK054_RS02460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BK054_RS02465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BK054_RS02470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BK054_RS02475	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BK054_RS02480	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BK054_RS02485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BK054_RS02490	COG0255	Belongs to the universal ribosomal protein uL29 family
BK054_RS02495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BK054_RS02500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BK054_RS02505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BK054_RS02510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BK054_RS02515	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BK054_RS02520	COG0089	rRNA binding
BK054_RS02525	COG0088	Forms part of the polypeptide exit tunnel
BK054_RS02530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BK054_RS02535	COG0051	transcription antitermination factor activity, RNA binding
BK054_RS02540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BK054_RS02545	COG0049	tRNA binding
BK054_RS02550	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BK054_RS02555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BK054_RS02570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BK054_RS02580	COG2003	Belongs to the UPF0758 family
BK054_RS02585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BK054_RS02600	COG3591	Belongs to the peptidase S1B family
BK054_RS02605	COG1320	monovalent cation:proton antiporter activity
BK054_RS02610	COG2212	antiporter activity
BK054_RS02615	COG1863	multisubunit Na H antiporter MnhE subunit
BK054_RS02620	COG0651	ATP synthesis coupled electron transport
BK054_RS02625	COG1006	Multisubunit Na H antiporter MnhC subunit
BK054_RS02635	COG2111	Na H antiporter
BK054_RS02635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BK054_RS02640	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BK054_RS02645	COG0563	adenylate kinase activity
BK054_RS02660	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BK054_RS02665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BK054_RS02795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BK054_RS02815	COG3655	Transcriptional regulator
BK054_RS02825	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BK054_RS02825	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BK054_RS02850	COG0671	phosphoesterase, PA-phosphatase related
BK054_RS02860	COG2814	Major facilitator Superfamily
BK054_RS02865	COG0697	spore germination
BK054_RS02880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BK054_RS02885	COG1127	ABC transporter
BK054_RS02915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BK054_RS02925	COG4206	TonB-dependent receptor
BK054_RS02925	COG1629	transport
BK054_RS02945	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BK054_RS02950	COG0085	RNA polymerase activity
BK054_RS02955	COG0222	ribosome binding
BK054_RS02960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BK054_RS02965	COG0081	regulation of translation
BK054_RS02970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BK054_RS03015	COG4974	Belongs to the 'phage' integrase family
BK054_RS03020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BK054_RS03035	COG3279	Response regulator of the LytR AlgR family
BK054_RS03040	COG3275	phosphorelay sensor kinase activity
BK054_RS03065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BK054_RS03080	COG1960	acyl-CoA dehydrogenase activity
BK054_RS03085	COG1555	photosystem II stabilization
BK054_RS03085	COG1596	polysaccharide export
BK054_RS03115	COG4206	TonB-dependent receptor
BK054_RS03115	COG1629	transport
BK054_RS03125	COG1629	transport
BK054_RS03130	COG0702	epimerase
BK054_RS03135	COG1629	transport
BK054_RS03145	COG1629	transport
BK054_RS03150	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BK054_RS03155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BK054_RS03160	COG1388	LysM domain
BK054_RS03160	COG0791	NLP P60 protein
BK054_RS03175	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BK054_RS03200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BK054_RS03205	COG0739	heme binding
BK054_RS03215	COG1704	LemA family
BK054_RS03235	COG1160	GTP binding
BK054_RS03240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BK054_RS03265	COG0488	(ABC) transporter
BK054_RS03290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BK054_RS03305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BK054_RS03330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BK054_RS03335	COG0459	protein refolding
BK054_RS03340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BK054_RS03345	COG0321	lipoyl(octanoyl) transferase activity
BK054_RS03350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BK054_RS03365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BK054_RS03375	COG1185	polyribonucleotide nucleotidyltransferase activity
BK054_RS03380	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BK054_RS03390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BK054_RS03390	COG0617	tRNA 3'-terminal CCA addition
BK054_RS03390	COG3620	sequence-specific DNA binding
BK054_RS03400	COG1610	YqeY-like protein
BK054_RS03440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BK054_RS03455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BK054_RS03460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BK054_RS03465	COG0772	Belongs to the SEDS family
BK054_RS03470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BK054_RS03475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BK054_RS03495	COG0275	rRNA processing
BK054_RS03500	COG2001	Belongs to the MraZ family
BK054_RS03510	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BK054_RS03525	COG1629	transport
BK054_RS03530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BK054_RS03535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BK054_RS03545	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BK054_RS03550	COG0463	Glycosyl transferase, family 2
BK054_RS03565	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BK054_RS03570	COG2363	Small membrane protein
BK054_RS03580	COG4172	Belongs to the ABC transporter superfamily
BK054_RS03600	COG4122	O-methyltransferase activity
BK054_RS03605	COG0671	phosphoesterase, PA-phosphatase related
BK054_RS03635	COG3340	Belongs to the peptidase S51 family
BK054_RS03685	COG1538	Outer membrane efflux protein
BK054_RS03695	COG3118	belongs to the thioredoxin family
BK054_RS03705	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BK054_RS03705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BK054_RS03720	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BK054_RS03725	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BK054_RS03730	COG0052	Belongs to the universal ribosomal protein uS2 family
BK054_RS03735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BK054_RS03740	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BK054_RS03765	COG0351	phosphomethylpyrimidine kinase
BK054_RS03770	COG0352	thiamine-phosphate diphosphorylase activity
BK054_RS03775	COG2022	thiamine diphosphate biosynthetic process
BK054_RS03780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BK054_RS03785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BK054_RS03790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BK054_RS03800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BK054_RS03805	COG3852	Histidine kinase
BK054_RS03815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BK054_RS03865	COG4771	TonB-dependent receptor
BK054_RS03870	COG1970	mechanosensitive ion channel activity
BK054_RS03875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BK054_RS03905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BK054_RS03905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BK054_RS03910	COG3118	belongs to the thioredoxin family
BK054_RS03915	COG0612	Peptidase, M16
BK054_RS03925	COG0481	GTPase activity
BK054_RS03950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BK054_RS03955	COG0693	protein deglycase activity
BK054_RS03960	COG0668	transmembrane transport
BK054_RS03975	COG0823	Involved in the tonB-independent uptake of proteins
BK054_RS03975	COG1506	peptidase
BK054_RS03980	COG1301	dicarboxylic acid transport
BK054_RS03985	COG0586	Pfam SNARE associated Golgi protein
BK054_RS03995	COG0492	ferredoxin-NADP+ reductase activity
BK054_RS04005	COG0489	protein tyrosine kinase activity
BK054_RS04015	COG0577	efflux transmembrane transporter activity
BK054_RS04040	COG0577	efflux transmembrane transporter activity
BK054_RS04060	COG1136	(ABC) transporter
BK054_RS04065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK054_RS04105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BK054_RS04110	COG5002	protein histidine kinase activity
BK054_RS04115	COG0745	RESPONSE REGULATOR receiver
BK054_RS04120	COG4771	TonB-dependent receptor
BK054_RS04150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BK054_RS04160	COG0358	DNA primase activity
BK054_RS04185	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BK054_RS04200	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BK054_RS04200	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BK054_RS04215	COG0113	porphobilinogen synthase activity
BK054_RS04220	COG0408	coproporphyrinogen oxidase activity
BK054_RS04230	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BK054_RS04240	COG0181	hydroxymethylbilane synthase activity
BK054_RS04245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BK054_RS04255	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BK054_RS04260	COG1981	membrane
BK054_RS04270	COG1024	Enoyl-CoA hydratase
BK054_RS04290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BK054_RS04300	COG0439	Biotin carboxylase
BK054_RS04305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BK054_RS04350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BK054_RS04360	COG0423	glycine-tRNA ligase activity
BK054_RS04375	COG1304	FMN binding
BK054_RS04390	COG0702	epimerase
BK054_RS04395	COG1027	Aspartate ammonia-lyase
BK054_RS04410	COG1040	competence protein
BK054_RS04425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BK054_RS04430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BK054_RS04435	COG1053	succinate dehydrogenase
BK054_RS04450	COG2267	carboxylic ester hydrolase activity
BK054_RS04470	COG1074	ATP-dependent DNA helicase activity
BK054_RS04475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BK054_RS04480	COG0469	pyruvate kinase activity
BK054_RS04490	COG0571	ribonuclease III activity
BK054_RS04495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BK054_RS04500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BK054_RS04510	COG0328	RNA-DNA hybrid ribonuclease activity
BK054_RS04515	COG1714	RDD family
BK054_RS04535	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BK054_RS04540	COG0471	metal ion transport
BK054_RS04545	COG1418	mRNA catabolic process
BK054_RS04575	COG0792	nuclease activity
BK054_RS04580	COG1619	proteins homologs of microcin C7 resistance protein MccF
BK054_RS04585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BK054_RS04600	COG2954	triphosphatase activity
BK054_RS04675	COG1335	isochorismatase
BK054_RS04685	COG4771	TonB-dependent receptor
BK054_RS04695	COG4607	ABC-type enterochelin transport system periplasmic component
BK054_RS04700	COG1902	pentaerythritol trinitrate reductase activity
BK054_RS04705	COG2814	Major facilitator Superfamily
BK054_RS04710	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BK054_RS04715	COG0193	aminoacyl-tRNA hydrolase activity
BK054_RS04720	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BK054_RS04725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BK054_RS04840	COG0750	zinc metalloprotease
BK054_RS04845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BK054_RS04855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BK054_RS04860	COG2239	Acts as a magnesium transporter
BK054_RS04865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BK054_RS04875	COG0708	Exodeoxyribonuclease III
BK054_RS04880	COG1360	Flagellar Motor Protein
BK054_RS04885	COG0668	transmembrane transport
BK054_RS04895	COG1570	exodeoxyribonuclease VII activity
BK054_RS04900	COG0756	dUTP diphosphatase activity
BK054_RS04925	COG1012	belongs to the aldehyde dehydrogenase family
BK054_RS04945	COG0714	Associated with various cellular activities
BK054_RS04960	COG2304	oxidoreductase activity
BK054_RS04965	COG2304	oxidoreductase activity
BK054_RS04995	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BK054_RS05005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BK054_RS05010	COG0165	Argininosuccinate lyase
BK054_RS05020	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BK054_RS05035	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BK054_RS05050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BK054_RS05055	COG0859	PFAM glycosyl transferase family 9
BK054_RS05065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BK054_RS05080	COG0151	Belongs to the GarS family
BK054_RS05150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BK054_RS05155	COG2183	response to ionizing radiation
BK054_RS05215	COG0698	ribose 5-phosphate isomerase
BK054_RS05220	COG0318	PFAM AMP-dependent synthetase and ligase
BK054_RS05235	COG0557	exoribonuclease II activity
BK054_RS05290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BK054_RS05290	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BK054_RS05295	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BK054_RS05305	COG1233	COG1233 Phytoene dehydrogenase and related
BK054_RS05315	COG1215	transferase activity, transferring glycosyl groups
BK054_RS05325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BK054_RS05365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BK054_RS05375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BK054_RS05390	COG1131	(ABC) transporter
BK054_RS05410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BK054_RS05415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BK054_RS05430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BK054_RS05440	COG1028	Short-chain dehydrogenase reductase Sdr
BK054_RS05460	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BK054_RS05465	COG0445	tRNA wobble uridine modification
BK054_RS05480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BK054_RS05485	COG0470	DNA polymerase III
BK054_RS05490	COG0126	phosphoglycerate kinase activity
BK054_RS05495	COG1388	LysM domain
BK054_RS05495	COG3942	CHAP domain
BK054_RS05505	COG3158	transport of potassium into the cell
BK054_RS05510	COG2365	Tyrosine phosphatase family
BK054_RS05515	COG0594	ribonuclease P activity
BK054_RS05530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BK054_RS05535	COG1943	Transposase
BK054_RS05540	COG0316	Belongs to the HesB IscA family
BK054_RS05545	COG0719	Fe-S assembly protein
BK054_RS05550	COG0396	ATPase activity
BK054_RS05555	COG0719	Fe-S assembly protein
BK054_RS05560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BK054_RS05570	COG3720	iron ion transport
BK054_RS05575	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BK054_RS05580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK054_RS05590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BK054_RS05595	COG2166	iron-sulfur cluster assembly
BK054_RS05600	COG2151	metal-sulfur cluster biosynthetic enzyme
BK054_RS05615	COG2502	aspartate--ammonia ligase
BK054_RS05620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BK054_RS05635	COG1607	acyl-coa hydrolase
BK054_RS05645	COG0758	DNA mediated transformation
BK054_RS05645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BK054_RS05650	COG0180	Tryptophanyl-tRNA synthetase
BK054_RS05670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BK054_RS05680	COG0242	peptide deformylase activity
BK054_RS05695	COG0826	peptidase U32
BK054_RS05710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BK054_RS05725	COG1561	YicC-like family, N-terminal region
BK054_RS05730	COG0194	GDP metabolic process
BK054_RS05735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BK054_RS05740	COG1979	alcohol dehydrogenase
BK054_RS05745	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BK054_RS05770	COG4152	abc transporter atp-binding protein
BK054_RS05795	COG0356	it plays a direct role in the translocation of protons across the membrane
BK054_RS05800	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BK054_RS05805	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BK054_RS05810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BK054_RS05815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BK054_RS05820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BK054_RS05840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BK054_RS05845	COG1774	PSP1 C-terminal conserved region
BK054_RS05860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BK054_RS05910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BK054_RS05910	COG3153	acetyltransferase
BK054_RS05920	COG0745	RESPONSE REGULATOR receiver
BK054_RS05925	COG5002	protein histidine kinase activity
BK054_RS05930	COG1285	pathogenesis
BK054_RS05935	COG2239	Acts as a magnesium transporter
BK054_RS05940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK054_RS05965	COG4206	TonB-dependent receptor
BK054_RS05965	COG1629	transport
BK054_RS05980	COG0612	Peptidase, M16
BK054_RS05985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BK054_RS05995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BK054_RS06005	COG1012	belongs to the aldehyde dehydrogenase family
BK054_RS06035	COG0517	IMP dehydrogenase activity
BK054_RS06035	COG0516	GMP reductase activity
BK054_RS06045	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BK054_RS06050	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BK054_RS06055	COG0297	glycogen (starch) synthase activity
BK054_RS06065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BK054_RS06070	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BK054_RS06075	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BK054_RS06085	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BK054_RS06105	COG2323	membrane
BK054_RS06110	COG3540	Alkaline phosphatase
BK054_RS06115	COG0501	Belongs to the peptidase M48B family
BK054_RS06135	COG1381	Involved in DNA repair and RecF pathway recombination
BK054_RS06140	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BK054_RS06150	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BK054_RS06155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BK054_RS06160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BK054_RS06185	COG0322	excinuclease ABC activity
BK054_RS06190	COG1752	Esterase of the alpha-beta hydrolase superfamily
BK054_RS06200	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BK054_RS06210	COG3483	tryptophan 2,3-dioxygenase activity
BK054_RS06215	COG0739	heme binding
BK054_RS06220	COG0166	Belongs to the GPI family
BK054_RS06225	COG1629	transport
BK054_RS06230	COG0667	Aldo Keto reductase
BK054_RS06235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BK054_RS06235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BK054_RS06270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BK054_RS06315	COG0527	aspartate kinase activity
BK054_RS06325	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BK054_RS06340	COG0793	Belongs to the peptidase S41A family
BK054_RS06345	COG3590	peptidase
BK054_RS06350	COG1999	signal sequence binding
BK054_RS06355	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BK054_RS06355	COG1918	ferrous iron import across plasma membrane
BK054_RS06365	COG0159	tryptophan synthase activity
BK054_RS06370	COG0133	tryptophan synthase activity
BK054_RS06375	COG0135	phosphoribosylanthranilate isomerase activity
BK054_RS06380	COG0134	indole-3-glycerol-phosphate synthase activity
BK054_RS06385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BK054_RS06390	COG0512	Glutamine amidotransferase of anthranilate synthase
BK054_RS06395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BK054_RS06400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK054_RS06410	COG1007	ATP synthesis coupled electron transport
BK054_RS06420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BK054_RS06425	COG0713	ATP synthesis coupled electron transport
BK054_RS06430	COG0839	Belongs to the complex I subunit 6 family
BK054_RS06435	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BK054_RS06440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BK054_RS06445	COG1034	ATP synthesis coupled electron transport
BK054_RS06450	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BK054_RS06455	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BK054_RS06460	COG0649	NAD binding
BK054_RS06465	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BK054_RS06470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BK054_RS06475	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BK054_RS06480	COG1278	Cold shock
BK054_RS06485	COG0439	Biotin carboxylase
BK054_RS06490	COG0511	ligase activity, forming carbon-carbon bonds
BK054_RS06495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BK054_RS06500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BK054_RS06510	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BK054_RS06535	COG0589	response to stress
BK054_RS06540	COG0779	Required for maturation of 30S ribosomal subunits
BK054_RS06545	COG0195	Participates in both transcription termination and antitermination
BK054_RS06550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BK054_RS06555	COG2738	Putative neutral zinc metallopeptidase
BK054_RS06565	COG0196	riboflavin kinase activity
BK054_RS06575	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BK054_RS06580	COG0720	synthase
BK054_RS06630	COG2814	Major facilitator Superfamily
BK054_RS06635	COG1435	thymidine kinase activity
BK054_RS06645	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BK054_RS06655	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BK054_RS06655	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BK054_RS06660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BK054_RS06670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BK054_RS06670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BK054_RS06700	COG0252	asparaginase activity
BK054_RS06710	COG0084	hydrolase, TatD family'
BK054_RS06750	COG0814	amino acid
BK054_RS06775	COG1505	serine-type exopeptidase activity
BK054_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
BK054_RS06795	COG0783	Belongs to the Dps family
BK054_RS06805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BK054_RS06810	COG0300	oxidoreductase activity
BK054_RS06820	COG1960	acyl-CoA dehydrogenase activity
BK054_RS06835	COG1051	belongs to the nudix hydrolase family
BK054_RS06845	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BK054_RS06865	COG0460	homoserine dehydrogenase
BK054_RS06865	COG0527	aspartate kinase activity
BK054_RS06870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BK054_RS06875	COG0626	cystathionine gamma-synthase activity
BK054_RS06885	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BK054_RS06900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BK054_RS06905	COG0228	four-way junction DNA binding
BK054_RS07050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BK054_RS07055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BK054_RS07165	COG3550	peptidyl-serine autophosphorylation
BK054_RS07200	COG3264	Mechanosensitive ion channel
BK054_RS07200	COG1196	nuclear chromosome segregation
BK054_RS07205	COG3757	hydrolase, family 25
BK054_RS07210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BK054_RS07220	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BK054_RS07235	COG0791	NLP P60 protein
BK054_RS07240	COG0658	competence protein
BK054_RS07240	COG2333	competence protein COMEC
BK054_RS07255	COG3104	oligopeptide transport
BK054_RS07280	COG0823	Involved in the tonB-independent uptake of proteins
BK054_RS07280	COG1506	peptidase
BK054_RS07340	COG2081	HI0933 family
BK054_RS07430	COG1187	pseudouridine synthase activity
BK054_RS07435	COG1741	Belongs to the pirin family
BK054_RS07440	COG0427	acetyl-CoA hydrolase
BK054_RS07455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK054_RS07470	COG1012	belongs to the aldehyde dehydrogenase family
BK054_RS07485	COG0357	Ribosomal RNA small subunit methyltransferase G
BK054_RS07490	COG0436	Aminotransferase
BK054_RS07500	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BK054_RS07510	COG2989	Protein conserved in bacteria
BK054_RS07515	COG4771	TonB-dependent receptor
BK054_RS07525	COG4221	oxidoreductase activity
BK054_RS07540	COG0754	glutathionylspermidine amidase activity
BK054_RS07605	COG3177	Filamentation induced by cAMP protein fic
BK054_RS07610	COG2003	Belongs to the UPF0758 family
BK054_RS07630	COG0358	DNA primase activity
BK054_RS07660	COG0346	lactoylglutathione lyase activity
BK054_RS07665	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BK054_RS07680	COG0326	Molecular chaperone. Has ATPase activity
BK054_RS07700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BK054_RS07715	COG1395	domain, Protein
BK054_RS07720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BK054_RS07745	COG1309	transcriptional regulator
BK054_RS07770	COG0567	Dehydrogenase, E1 component
BK054_RS07775	COG0508	dehydrogenase complex catalyzes the overall conversion of
BK054_RS07780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BK054_RS07785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BK054_RS07785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BK054_RS07800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BK054_RS07805	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BK054_RS07815	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BK054_RS07820	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BK054_RS07825	COG0612	Peptidase, M16
BK054_RS07830	COG0612	Peptidase, M16
BK054_RS07845	COG0629	single-stranded DNA binding
BK054_RS07850	COG1194	a g-specific adenine glycosylase
BK054_RS07855	COG0776	regulation of translation
BK054_RS07860	COG1530	ribonuclease E activity
BK054_RS07865	COG4953	penicillin-binding protein 1C
BK054_RS07870	COG2373	Large extracellular alpha-helical protein
BK054_RS07880	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BK054_RS07900	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BK054_RS07905	COG0017	Asparaginyl-tRNA synthetase
BK054_RS07915	COG0233	cytoplasmic translational termination
BK054_RS07920	COG0528	UMP kinase activity
BK054_RS07960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BK054_RS07965	COG1968	undecaprenyl-diphosphatase activity
BK054_RS07975	COG2177	Part of the ABC transporter FtsEX involved in
BK054_RS07980	COG0495	leucyl-tRNA aminoacylation
BK054_RS07990	COG2010	Cytochrome c
BK054_RS07995	COG0437	4 iron, 4 sulfur cluster binding
BK054_RS08020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BK054_RS08025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BK054_RS08030	COG2255	four-way junction helicase activity
BK054_RS08035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BK054_RS08040	COG0280	phosphate acetyltransferase
BK054_RS08040	COG0281	malic enzyme
BK054_RS08045	COG0632	four-way junction helicase activity
BK054_RS08055	COG0509	glycine decarboxylation via glycine cleavage system
BK054_RS08065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BK054_RS08070	COG0109	protoheme IX farnesyltransferase activity
BK054_RS08095	COG1999	signal sequence binding
BK054_RS08100	COG2322	membrane
BK054_RS08115	COG1566	PFAM secretion protein HlyD family protein
BK054_RS08120	COG1214	PFAM Peptidase M22, glycoprotease
BK054_RS08125	COG0668	transmembrane transport
BK054_RS08130	COG1331	Highly conserved protein containing a thioredoxin domain
BK054_RS08155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BK054_RS08160	COG0596	Alpha beta hydrolase
BK054_RS08165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BK054_RS08175	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BK054_RS08185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BK054_RS08205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BK054_RS08220	COG1950	PFAM Membrane protein of
BK054_RS08235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BK054_RS08265	COG1917	Cupin 2, conserved barrel domain protein
BK054_RS08265	COG4977	sequence-specific DNA binding
BK054_RS08295	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BK054_RS08330	COG2003	Belongs to the UPF0758 family
BK054_RS08395	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BK054_RS08430	COG2353	YceI-like domain
BK054_RS08445	COG1428	Deoxynucleoside kinase
BK054_RS08450	COG0616	signal peptide processing
BK054_RS08475	COG4717	serine-type aminopeptidase activity
BK054_RS08490	COG2814	Major facilitator Superfamily
BK054_RS08495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BK054_RS08500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BK054_RS08520	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BK054_RS08545	COG0772	Belongs to the SEDS family
BK054_RS08550	COG0768	penicillin binding
BK054_RS08565	COG1077	Cell shape determining protein MreB Mrl
BK054_RS08570	COG0138	bifunctional purine biosynthesis protein purh
BK054_RS08575	COG1136	(ABC) transporter
BK054_RS08575	COG0577	efflux transmembrane transporter activity
BK054_RS08580	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BK054_RS08605	COG2226	methyltransferase
BK054_RS08615	COG1115	amino acid carrier protein
BK054_RS08625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BK054_RS08635	COG0508	dehydrogenase complex catalyzes the overall conversion of
BK054_RS08635	COG0022	dehydrogenase e1 component
BK054_RS08650	COG2086	electron transfer activity
BK054_RS08655	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BK054_RS08665	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BK054_RS08675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BK054_RS08685	COG1428	Deoxynucleoside kinase
BK054_RS08690	COG1522	sequence-specific DNA binding
BK054_RS08695	COG1629	transport
BK054_RS08705	COG1131	(ABC) transporter
BK054_RS08715	COG0730	response to heat
BK054_RS08720	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BK054_RS08725	COG1162	GTPase activity
BK054_RS08745	COG0612	Peptidase, M16
BK054_RS08760	COG4206	TonB-dependent receptor
BK054_RS08760	COG1629	transport
BK054_RS08775	COG1228	amidohydrolase
BK054_RS08780	COG1490	D-aminoacyl-tRNA deacylase activity
BK054_RS08795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BK054_RS08800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BK054_RS08805	COG3844	kynureninase activity
BK054_RS08810	COG0010	Belongs to the arginase family
BK054_RS08815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BK054_RS08820	COG0433	COG0433 Predicted ATPase
BK054_RS08825	COG0811	peptide transport
BK054_RS08860	COG0602	queuosine metabolic process
BK054_RS08870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BK054_RS08885	COG3279	Response regulator of the LytR AlgR family
BK054_RS08890	COG0702	epimerase
BK054_RS08905	COG2972	Histidine kinase
BK054_RS08910	COG3876	Protein conserved in bacteria
BK054_RS08915	COG0577	efflux transmembrane transporter activity
BK054_RS08930	COG1917	Cupin 2, conserved barrel domain protein
BK054_RS08930	COG2169	Transcriptional regulator
BK054_RS08980	COG0545	Peptidyl-prolyl cis-trans isomerase
BK054_RS08985	COG2207	Transcriptional regulator
BK054_RS08985	COG4753	response regulator
BK054_RS09000	COG1114	Component of the transport system for branched-chain amino acids
BK054_RS09015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BK054_RS09065	COG2217	Heavy metal translocating P-type atpase
BK054_RS09075	COG3047	cAMP biosynthetic process
BK054_RS09085	COG4145	pantothenate transmembrane transporter activity
BK054_RS09090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BK054_RS09100	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BK054_RS09135	COG2949	membrane
BK054_RS09140	COG0513	Belongs to the DEAD box helicase family
BK054_RS09155	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BK054_RS09155	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BK054_RS09160	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BK054_RS09160	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BK054_RS09170	COG0572	uridine kinase
BK054_RS09185	COG0527	aspartate kinase activity
BK054_RS09190	COG0019	diaminopimelate decarboxylase activity
BK054_RS09210	COG2264	protein methyltransferase activity
BK054_RS09220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BK054_RS09225	COG1690	Belongs to the RtcB family
BK054_RS09240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BK054_RS09250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BK054_RS09255	COG1181	Belongs to the D-alanine--D-alanine ligase family
BK054_RS09265	COG0564	pseudouridine synthase activity
BK054_RS09270	COG0037	tRNA processing
BK054_RS09290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BK054_RS09295	COG1132	(ABC) transporter
BK054_RS09300	COG0101	tRNA pseudouridine synthase activity
BK054_RS09345	COG1136	(ABC) transporter
BK054_RS09350	COG2096	Adenosyltransferase
BK054_RS09360	COG0653	protein targeting
BK054_RS09365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BK054_RS09375	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BK054_RS09380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BK054_RS09385	COG2217	Heavy metal translocating P-type atpase
BK054_RS09395	COG3278	Belongs to the heme-copper respiratory oxidase family
BK054_RS09410	COG0348	domain, Protein
BK054_RS09430	COG0681	Belongs to the peptidase S26 family
BK054_RS09435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BK054_RS09445	COG1475	DNA binding
BK054_RS09450	COG1192	Involved in chromosome partitioning
BK054_RS09455	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BK054_RS09485	COG0662	Cupin 2, conserved barrel domain protein
BK054_RS09485	COG2207	Transcriptional regulator
BK054_RS09490	COG2226	methyltransferase
BK054_RS09495	COG0456	acetyltransferase
BK054_RS09555	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BK054_RS09565	COG0326	Molecular chaperone. Has ATPase activity
BK054_RS09575	COG2885	chlorophyll binding
BK054_RS09595	COG1090	epimerase
BK054_RS09600	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BK054_RS09605	COG0484	heat shock protein binding
BK054_RS09610	COG4152	abc transporter atp-binding protein
BK054_RS09620	COG2204	response regulator
BK054_RS09645	COG2249	NAD(P)H dehydrogenase (quinone) activity
BK054_RS09665	COG1678	Uncharacterized ACR, COG1678
BK054_RS09675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BK054_RS09680	COG0514	ATP-dependent DNA helicase (RecQ)
BK054_RS09700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BK054_RS09710	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BK054_RS09720	COG4974	Belongs to the 'phage' integrase family
BK054_RS09725	COG1418	mRNA catabolic process
BK054_RS09765	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BK054_RS09770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BK054_RS09785	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BK054_RS09800	COG1335	isochorismatase
BK054_RS09835	COG0659	secondary active sulfate transmembrane transporter activity
BK054_RS09840	COG1131	(ABC) transporter
BK054_RS09850	COG0335	large ribosomal subunit rRNA binding
BK054_RS09855	COG1609	Transcriptional regulator
BK054_RS09855	COG2207	Transcriptional regulator
BK054_RS09870	COG0336	Belongs to the RNA methyltransferase TrmD family
BK054_RS09880	COG2814	Major facilitator Superfamily
BK054_RS09885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BK054_RS09890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BK054_RS09895	COG0697	spore germination
BK054_RS09900	COG0069	glutamate synthase activity
BK054_RS09905	COG0038	chloride channel
BK054_RS09915	COG1132	(ABC) transporter
BK054_RS09920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BK054_RS09930	COG1862	Preprotein translocase
BK054_RS09935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BK054_RS09940	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BK054_RS09945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BK054_RS09950	COG0488	(ABC) transporter
BK054_RS09960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK054_RS09980	COG2326	polyphosphate kinase activity
BK054_RS09990	COG0534	Mate efflux family protein
BK054_RS10000	COG1703	isobutyryl-CoA mutase activity
BK054_RS10005	COG2223	nitrite transmembrane transporter activity
BK054_RS10015	COG2239	Acts as a magnesium transporter
BK054_RS10035	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BK054_RS10050	COG0473	3-isopropylmalate dehydrogenase activity
BK054_RS10055	COG0066	3-isopropylmalate dehydratase activity
BK054_RS10060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BK054_RS10065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BK054_RS10105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BK054_RS10115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BK054_RS10120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BK054_RS10130	COG4771	TonB-dependent receptor
BK054_RS10185	COG4682	membrane
BK054_RS10195	COG0577	efflux transmembrane transporter activity
BK054_RS10200	COG0124	histidyl-tRNA synthetase
BK054_RS10215	COG0753	catalase activity
BK054_RS10235	COG2733	membrane
BK054_RS10240	COG0564	pseudouridine synthase activity
BK054_RS10270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BK054_RS10275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BK054_RS10335	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BK054_RS10345	COG1663	tetraacyldisaccharide 4'-kinase activity
BK054_RS10350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BK054_RS10365	COG1187	pseudouridine synthase activity
BK054_RS10420	COG3829	transcription factor binding
BK054_RS10430	COG3621	Patatin-like phospholipase
BK054_RS10455	COG2378	regulation of single-species biofilm formation
BK054_RS10480	COG0300	oxidoreductase activity
BK054_RS10490	COG1063	alcohol dehydrogenase
BK054_RS10500	COG0583	DNA-binding transcription factor activity
BK054_RS10505	COG4221	oxidoreductase activity
BK054_RS10510	COG2207	Transcriptional regulator
BK054_RS10525	COG0596	Alpha beta hydrolase
BK054_RS10560	COG4372	Transposase
BK054_RS10610	COG4974	Belongs to the 'phage' integrase family
BK054_RS10630	COG1506	peptidase
BK054_RS10635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BK054_RS10645	COG2356	endonuclease I
BK054_RS10655	COG0586	Pfam SNARE associated Golgi protein
BK054_RS10660	COG2356	endonuclease I
BK054_RS10665	COG2356	endonuclease I
BK054_RS10670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BK054_RS10670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BK054_RS10685	COG1595	DNA-templated transcription, initiation
BK054_RS10690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK054_RS10700	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BK054_RS10710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BK054_RS10745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BK054_RS10750	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BK054_RS10760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BK054_RS10775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK054_RS10780	COG0606	chelatase, subunit chli
BK054_RS10790	COG2321	neutral zinc metallopeptidase
BK054_RS10800	COG4773	Receptor
BK054_RS10805	COG2207	Transcriptional regulator
BK054_RS10810	COG0217	transcriptional regulatory protein
BK054_RS10815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BK054_RS10825	COG2217	Heavy metal translocating P-type atpase
BK054_RS10840	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BK054_RS10850	COG0564	pseudouridine synthase activity
BK054_RS10855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BK054_RS10865	COG1760	l-serine dehydratase
BK054_RS10870	COG0443	Heat shock 70 kDa protein
BK054_RS10910	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BK054_RS10960	COG2204	response regulator
BK054_RS10970	COG0318	PFAM AMP-dependent synthetase and ligase
BK054_RS10975	COG1506	peptidase
BK054_RS10975	COG0823	Involved in the tonB-independent uptake of proteins
BK054_RS10990	COG0673	inositol 2-dehydrogenase activity
BK054_RS11005	COG0116	Belongs to the methyltransferase superfamily
BK054_RS11005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BK054_RS11075	COG0497	DNA recombination
BK054_RS11090	COG0405	Gamma-glutamyltransferase
BK054_RS11105	COG1289	transmembrane transporter activity
BK054_RS11150	COG0339	signal peptide processing
BK054_RS11195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BK054_RS11205	COG0288	reversible hydration of carbon dioxide
BK054_RS11215	COG4067	protein conserved in archaea
BK054_RS11215	COG0189	ligase activity
BK054_RS11220	COG0542	response to heat
BK054_RS11225	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BK054_RS11240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BK054_RS11250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BK054_RS11260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BK054_RS11270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BK054_RS11285	COG2207	Transcriptional regulator
BK054_RS11290	COG0477	Major facilitator Superfamily
BK054_RS11305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BK054_RS11310	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BK054_RS11315	COG0714	Associated with various cellular activities
BK054_RS11345	COG2860	membrane
BK054_RS11360	COG0424	maF-like protein
BK054_RS11365	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BK054_RS11375	COG2346	COG2346, Truncated hemoglobins
BK054_RS11400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BK054_RS11430	COG1368	sulfuric ester hydrolase activity
BK054_RS11435	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BK054_RS11450	COG2814	Major facilitator Superfamily
BK054_RS11455	COG0583	DNA-binding transcription factor activity
BK054_RS11460	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK054_RS11465	COG4605	iron ion homeostasis
BK054_RS11470	COG4604	ABC transporter, ATP-binding protein
BK054_RS11475	COG4607	ABC-type enterochelin transport system periplasmic component
BK054_RS11480	COG1607	acyl-coa hydrolase
BK054_RS11495	COG0022	dehydrogenase e1 component
BK054_RS11500	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BK054_RS11510	COG0022	dehydrogenase e1 component
BK054_RS11515	COG0156	8-amino-7-oxononanoate synthase activity
BK054_RS11520	COG2814	Major facilitator Superfamily
BK054_RS11535	COG1363	Peptidase, m42
BK054_RS11545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BK054_RS11555	COG2996	Protein conserved in bacteria
BK054_RS11570	COG4771	TonB-dependent receptor
BK054_RS11575	COG0745	RESPONSE REGULATOR receiver
BK054_RS11575	COG3292	Two component regulator propeller
BK054_RS11575	COG2205	protein histidine kinase activity
BK054_RS11580	COG0745	RESPONSE REGULATOR receiver
BK054_RS11590	COG3275	phosphorelay sensor kinase activity
BK054_RS11595	COG3279	Response regulator of the LytR AlgR family
BK054_RS11600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK054_RS11645	COG4372	Transposase
BK054_RS11685	COG4372	Transposase
BK054_RS11745	COG0456	acetyltransferase
BK054_RS11760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK054_RS11785	COG2169	Transcriptional regulator
BK054_RS11790	COG4221	oxidoreductase activity
BK054_RS11835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BK054_RS11840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BK054_RS11845	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BK054_RS11850	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BK054_RS11860	COG2884	Cell division ATP-binding protein ftsE
BK054_RS11870	COG1346	cytolysis
BK054_RS11890	COG0187	DNA topoisomerase II activity
BK054_RS11900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BK054_RS11915	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BK054_RS11920	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BK054_RS11925	COG0215	cysteine-tRNA ligase activity
BK054_RS11930	COG0302	gtp cyclohydrolase
BK054_RS11950	COG2059	Chromate
BK054_RS11995	COG0688	phosphatidylethanolamine metabolic process
BK054_RS12000	COG2059	Chromate
BK054_RS12010	COG3425	synthase
BK054_RS12020	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BK054_RS12050	COG1917	Cupin 2, conserved barrel domain protein
BK054_RS12050	COG2207	Transcriptional regulator
BK054_RS12055	COG0110	maltose O-acetyltransferase activity
BK054_RS12060	COG1064	alcohol dehydrogenase
BK054_RS12070	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BK054_RS12090	COG1215	transferase activity, transferring glycosyl groups
BK054_RS12110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BK054_RS12125	COG1024	Enoyl-CoA hydratase
BK054_RS12175	COG0628	permease
BK054_RS12180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BK054_RS12185	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BK054_RS12195	COG0205	6-phosphofructokinase activity
BK054_RS12220	COG0251	oxidation-reduction process
BK054_RS12230	COG0860	N-Acetylmuramoyl-L-alanine amidase
BK054_RS12235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BK054_RS12245	COG0247	lactate metabolic process
BK054_RS12245	COG2181	nitrate reductase activity
BK054_RS12255	COG1472	Belongs to the glycosyl hydrolase 3 family
BK054_RS12260	COG4771	TonB-dependent receptor
BK054_RS12295	COG2249	NAD(P)H dehydrogenase (quinone) activity
BK054_RS12300	COG3118	belongs to the thioredoxin family
BK054_RS12310	COG2207	Transcriptional regulator
BK054_RS12345	COG1733	regulation of RNA biosynthetic process
BK054_RS12385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK054_RS12405	COG2195	Cleaves the N-terminal amino acid of tripeptides
BK054_RS12420	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BK054_RS12425	COG0284	orotidine-5'-phosphate decarboxylase activity
BK054_RS12430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BK054_RS12445	COG0210	DNA helicase
BK054_RS12450	COG0009	L-threonylcarbamoyladenylate synthase
BK054_RS12455	COG0045	succinate-CoA ligase (ADP-forming) activity
BK054_RS12460	COG4807	Protein conserved in bacteria
BK054_RS12465	COG0556	nucleotide-excision repair
BK054_RS12475	COG1051	belongs to the nudix hydrolase family
BK054_RS12480	COG2814	Major facilitator Superfamily
BK054_RS12490	COG1960	acyl-CoA dehydrogenase activity
BK054_RS12495	COG0183	Belongs to the thiolase family
BK054_RS12500	COG1024	Enoyl-CoA hydratase
BK054_RS12500	COG1250	3-hydroxyacyl-CoA dehydrogenase
BK054_RS12510	COG1022	Amp-dependent synthetase and ligase
BK054_RS12515	COG1368	sulfuric ester hydrolase activity
BK054_RS12520	COG1368	sulfuric ester hydrolase activity
BK054_RS12540	COG0484	heat shock protein binding
BK054_RS12550	COG0542	response to heat
BK054_RS12615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BK054_RS12625	COG1012	belongs to the aldehyde dehydrogenase family
BK054_RS12640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BK054_RS12660	COG1253	flavin adenine dinucleotide binding
BK054_RS12670	COG0460	homoserine dehydrogenase
BK054_RS12670	COG0527	aspartate kinase activity
BK054_RS12675	COG0083	homoserine kinase activity
BK054_RS12680	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BK054_RS12685	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BK054_RS12730	COG0288	reversible hydration of carbon dioxide
BK054_RS12765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BK054_RS12810	COG1104	cysteine desulfurase activity
BK054_RS12815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BK054_RS12820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BK054_RS12825	COG0579	oxidoreductase
BK054_RS12840	COG4452	Inner membrane protein CreD
BK054_RS12860	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BK054_RS12860	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BK054_RS12860	COG1703	isobutyryl-CoA mutase activity
BK054_RS12870	COG3011	Protein conserved in bacteria
BK054_RS12875	COG1193	negative regulation of DNA recombination
BK054_RS12890	COG0427	acetyl-CoA hydrolase
BK054_RS12900	COG0321	lipoyl(octanoyl) transferase activity
BK054_RS12900	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BK054_RS12935	COG0513	Belongs to the DEAD box helicase family
BK054_RS12940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BK054_RS12945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BK054_RS12970	COG0802	atpase or kinase
BK054_RS12975	COG2204	response regulator
BK054_RS12980	COG1216	Glycosyl transferase, family 2
BK054_RS12980	COG0463	Glycosyl transferase, family 2
BK054_RS12985	COG0237	dephospho-CoA kinase activity
BK054_RS13020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BK054_RS13025	COG2363	Small membrane protein
BK054_RS13040	COG0427	acetyl-CoA hydrolase
BK054_RS13045	COG0813	purine-nucleoside phosphorylase activity
BK054_RS13050	COG0023	Translation Initiation Factor
BK054_RS13065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BK054_RS13075	COG1702	phosphate starvation-inducible protein PhoH
BK054_RS13115	COG3279	Response regulator of the LytR AlgR family
BK054_RS13120	COG0475	glutathione-regulated potassium exporter activity
BK054_RS13145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BK054_RS13200	COG3645	SOS response
BK054_RS13210	COG0488	(ABC) transporter
BK054_RS13215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BK054_RS13220	COG0786	glutamate:sodium symporter activity
BK054_RS13225	COG0519	Catalyzes the synthesis of GMP from XMP
BK054_RS13225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BK054_RS13230	COG0860	N-Acetylmuramoyl-L-alanine amidase
BK054_RS13230	COG1388	LysM domain
BK054_RS13235	COG3530	Putative quorum-sensing-regulated virulence factor
BK054_RS13240	COG1252	NADH dehydrogenase
BK054_RS13275	COG0456	acetyltransferase
BK054_RS13280	COG3275	phosphorelay sensor kinase activity
BK054_RS13320	COG1629	transport
BK054_RS13320	COG4206	TonB-dependent receptor
BK054_RS13325	COG0702	epimerase
BK054_RS13330	COG1785	Belongs to the alkaline phosphatase family
BK054_RS13355	COG0006	proline dipeptidase activity
BK054_RS13370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BK054_RS13375	COG5002	protein histidine kinase activity
BK054_RS13385	COG0010	Belongs to the arginase family
BK054_RS13390	COG1228	amidohydrolase
BK054_RS13395	COG0598	Magnesium transport protein CorA
BK054_RS13400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BK054_RS13430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BK054_RS13435	COG3457	Alanine racemase
BK054_RS13450	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BK054_RS13465	COG1522	sequence-specific DNA binding
BK054_RS13470	COG1988	membrane-bound metal-dependent
BK054_RS13480	COG3844	kynureninase activity
BK054_RS13515	COG2814	Major facilitator Superfamily
BK054_RS13550	COG1858	cytochrome C peroxidase
BK054_RS13560	COG3022	response to hydroperoxide
BK054_RS13565	COG2986	histidine ammonia-lyase
BK054_RS13570	COG1078	dGTPase activity
BK054_RS13575	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BK054_RS13580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BK054_RS13580	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BK054_RS13585	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BK054_RS13590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BK054_RS13595	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BK054_RS13630	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BK054_RS13630	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BK054_RS13635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BK054_RS13660	COG0488	(ABC) transporter
BK054_RS13680	COG1943	Transposase
BK054_RS13690	COG2234	aminopeptidase activity
BK054_RS13695	COG0300	oxidoreductase activity
BK054_RS13700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BK054_RS13745	COG1506	peptidase
BK054_RS13745	COG0823	Involved in the tonB-independent uptake of proteins
BK054_RS13750	COG1028	Short-chain dehydrogenase reductase Sdr
BK054_RS13795	COG2814	Major facilitator Superfamily
BK054_RS13810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK054_RS13825	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BK054_RS13840	COG2197	response regulator
BK054_RS13855	COG1028	Short-chain dehydrogenase reductase Sdr
BK054_RS13860	COG2207	Transcriptional regulator
BK054_RS13895	COG1917	Cupin 2, conserved barrel domain protein
BK054_RS13895	COG4977	sequence-specific DNA binding
BK054_RS13905	COG1566	PFAM secretion protein HlyD family protein
BK054_RS13930	COG0242	peptide deformylase activity
BK054_RS13940	COG3956	TIGRFAM MazG family protein
BK054_RS13965	COG0009	L-threonylcarbamoyladenylate synthase
BK054_RS13975	COG1169	isochorismate synthase
BK054_RS13980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BK054_RS14035	COG1335	isochorismatase
BK054_RS14085	COG1917	Cupin 2, conserved barrel domain protein
BK054_RS14085	COG4977	sequence-specific DNA binding
BK054_RS14115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BK054_RS14130	COG2818	Glycosylase
BK054_RS14145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BK054_RS14150	COG0569	domain protein
BK054_RS14155	COG3384	dioxygenase
BK054_RS14190	COG1575	Belongs to the MenA family. Type 1 subfamily
BK054_RS14195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BK054_RS14200	COG4948	Mandelate Racemase Muconate Lactonizing
BK054_RS14205	COG2169	Transcriptional regulator
BK054_RS14210	COG0697	spore germination
BK054_RS14230	COG1295	ribonuclease BN
BK054_RS14255	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BK054_RS14325	COG0656	L-ascorbic acid biosynthetic process
BK054_RS14355	COG0730	response to heat
BK054_RS14365	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BK054_RS14370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BK054_RS14370	COG1648	precorrin-2 dehydrogenase activity
BK054_RS14385	COG2895	sulfate adenylyltransferase (ATP) activity
BK054_RS14390	COG0175	sulfate reduction
BK054_RS14395	COG0175	sulfate reduction
BK054_RS14400	COG1959	2 iron, 2 sulfur cluster binding
BK054_RS14410	COG1733	regulation of RNA biosynthetic process
BK054_RS14415	COG4628	conserved protein (DUF2132)
BK054_RS14440	COG0640	Transcriptional regulator
BK054_RS14450	COG0387	Pfam Sodium calcium exchanger
BK054_RS14470	COG4771	TonB-dependent receptor
BK054_RS14480	COG0573	inorganic phosphate transmembrane transporter activity
BK054_RS14485	COG0581	inorganic phosphate transmembrane transporter activity
BK054_RS14490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BK054_RS14545	COG2249	NAD(P)H dehydrogenase (quinone) activity
BK054_RS14550	COG1733	regulation of RNA biosynthetic process
BK054_RS14560	COG1858	cytochrome C peroxidase
BK054_RS14610	COG4106	trans-aconitate 2-methyltransferase activity
BK054_RS14635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK054_RS14640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BK054_RS14645	COG0596	Alpha beta hydrolase
BK054_RS14650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK054_RS14670	COG3278	Belongs to the heme-copper respiratory oxidase family
BK054_RS14675	COG1484	DNA-dependent DNA replication
BK054_RS14680	COG4584	PFAM Integrase catalytic
BK054_RS14700	COG4372	Transposase
BK054_RS14755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BK054_RS14775	COG4372	Transposase
BK054_RS14825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BK054_RS14835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BK054_RS14855	COG1054	Belongs to the UPF0176 family
BK054_RS14860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BK054_RS14870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BK054_RS14880	COG0482	sulfurtransferase activity
BK054_RS14890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BK054_RS14895	COG0706	membrane insertase activity
BK054_RS14900	COG0504	CTP synthase activity
BK054_RS14910	COG0833	amino acid
BK054_RS14925	COG2252	PERMEase
BK054_RS14970	COG1063	alcohol dehydrogenase
BK054_RS14980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BK054_RS14985	COG1611	Belongs to the LOG family
BK054_RS14990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BK054_RS14995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BK054_RS15000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BK054_RS15005	COG3279	Response regulator of the LytR AlgR family
BK054_RS15015	COG3275	phosphorelay sensor kinase activity
BK054_RS15045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BK054_RS15050	COG1136	(ABC) transporter
BK054_RS15060	COG0248	Ppx GppA phosphatase
BK054_RS15065	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BK054_RS15080	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BK054_RS15110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BK054_RS15125	COG1139	Iron-sulfur cluster binding protein
BK054_RS15130	COG0247	lactate metabolic process
BK054_RS15135	COG1620	l-lactate permease
BK054_RS15155	COG2226	methyltransferase
BK054_RS15185	COG1028	Short-chain dehydrogenase reductase Sdr
BK054_RS15190	COG1757	Na H antiporter
BK054_RS15250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BK054_RS15260	COG1132	(ABC) transporter
BK054_RS15280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BK054_RS15290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BK054_RS15295	COG0673	inositol 2-dehydrogenase activity
BK054_RS15300	COG1250	3-hydroxyacyl-CoA dehydrogenase
BK054_RS15310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BK054_RS15315	COG2176	DNA-directed DNA polymerase activity
BK054_RS15320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BK054_RS15325	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BK054_RS15350	COG2814	Major facilitator Superfamily
BK054_RS15370	COG0702	epimerase
BK054_RS15375	COG4771	TonB-dependent receptor
BK054_RS15400	COG1566	PFAM secretion protein HlyD family protein
BK054_RS15440	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK054_RS15470	COG1396	sequence-specific DNA binding
BK054_RS15525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BK054_RS15530	COG0363	glucosamine-6-phosphate deaminase activity
BK054_RS15540	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BK054_RS15540	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BK054_RS15555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BK054_RS15565	COG5434	Belongs to the glycosyl hydrolase 28 family
BK054_RS15580	COG0438	transferase activity, transferring glycosyl groups
BK054_RS15595	COG1216	Glycosyl transferase, family 2
BK054_RS15595	COG0463	Glycosyl transferase, family 2
BK054_RS15610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BK054_RS15615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BK054_RS15620	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BK054_RS15625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BK054_RS15630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BK054_RS15690	COG2353	YceI-like domain
BK054_RS15710	COG1629	transport
BK054_RS15770	COG1278	Cold shock
BK054_RS15780	COG0793	Belongs to the peptidase S41A family
BK054_RS15780	COG3409	Peptidoglycan-binding domain 1 protein
BK054_RS15800	COG2197	response regulator
BK054_RS15805	COG4585	Histidine kinase
BK054_RS15850	COG2885	chlorophyll binding
BK054_RS15880	COG1396	sequence-specific DNA binding
BK054_RS15885	COG3550	peptidyl-serine autophosphorylation
BK054_RS15890	COG3550	peptidyl-serine autophosphorylation
BK054_RS16035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BK054_RS16060	COG4585	Histidine kinase
BK054_RS16080	COG1088	dTDP-glucose 4,6-dehydratase activity
BK054_RS16085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BK054_RS16090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BK054_RS16095	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BK054_RS16105	COG0513	Belongs to the DEAD box helicase family
BK054_RS16110	COG1278	Cold shock
BK054_RS16115	COG1278	Cold shock
BK054_RS16150	COG2837	iron assimilation
BK054_RS16170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BK054_RS16175	COG4106	trans-aconitate 2-methyltransferase activity
BK054_RS16175	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BK054_RS16180	COG0156	8-amino-7-oxononanoate synthase activity
BK054_RS16220	COG0604	alcohol dehydrogenase
BK054_RS16240	COG0328	RNA-DNA hybrid ribonuclease activity
BK054_RS16255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BK054_RS16265	COG2207	Transcriptional regulator
BK054_RS16265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BK054_RS16290	COG1629	transport
BK054_RS16300	COG1595	DNA-templated transcription, initiation
BK054_RS16315	COG1629	transport
BK054_RS16320	COG0702	epimerase
BK054_RS16325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BK054_RS16345	COG3118	belongs to the thioredoxin family
BK054_RS16360	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BK054_RS16375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BK054_RS16375	COG0456	acetyltransferase
BK054_RS16390	COG0730	response to heat
BK054_RS16405	COG2207	Transcriptional regulator
BK054_RS16405	COG4753	response regulator
BK054_RS16410	COG4413	Urea transporter
BK054_RS16415	COG0829	nickel cation binding
BK054_RS16420	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BK054_RS16430	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BK054_RS16435	COG0804	urea catabolic process
BK054_RS16440	COG0832	Belongs to the urease beta subunit family
BK054_RS16445	COG0831	urea catabolic process
BK054_RS16460	COG2312	Erythromycin esterase
BK054_RS16470	COG0653	protein targeting
BK054_RS16485	COG1120	ATPase activity
BK054_RS16490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK054_RS16505	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BK054_RS16510	COG0375	protein maturation
BK054_RS16525	COG1733	regulation of RNA biosynthetic process
BK054_RS16530	COG0778	Nitroreductase
BK054_RS16535	COG1846	Transcriptional regulator
BK054_RS16585	COG4774	siderophore transport
BK054_RS16595	COG1733	regulation of RNA biosynthetic process
BK054_RS16600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BK054_RS16625	COG0477	Major facilitator Superfamily
BK054_RS16665	COG1191	sigma factor activity
BK054_RS16695	COG2249	NAD(P)H dehydrogenase (quinone) activity
BK054_RS16700	COG1733	regulation of RNA biosynthetic process
BK054_RS16715	COG0259	pyridoxamine-phosphate oxidase activity
BK054_RS16720	COG1234	tRNA 3'-trailer cleavage
BK054_RS16765	COG0540	Belongs to the ATCase OTCase family
BK054_RS16770	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BK054_RS16785	COG0431	NADPH-dependent FMN reductase
BK054_RS16790	COG2885	chlorophyll binding
BK054_RS16795	COG4122	O-methyltransferase activity
BK054_RS16800	COG0077	Prephenate dehydratase
BK054_RS16800	COG1605	Chorismate mutase
BK054_RS16810	COG0386	Belongs to the glutathione peroxidase family
BK054_RS16815	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BK054_RS16825	COG0402	S-adenosylhomocysteine deaminase activity
BK054_RS16830	COG0666	response to abiotic stimulus
BK054_RS16835	COG2207	Transcriptional regulator
BK054_RS16845	COG5006	permease, DMT superfamily
BK054_RS16855	COG0438	transferase activity, transferring glycosyl groups
BK054_RS16870	COG2814	Major facilitator Superfamily
BK054_RS16890	COG3609	addiction module antidote protein, CC2985 family
BK054_RS16910	COG0471	metal ion transport
BK054_RS16915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BK054_RS16920	COG4589	Belongs to the CDS family
BK054_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
BK054_RS16940	COG2267	carboxylic ester hydrolase activity
BK054_RS16955	COG2972	Histidine kinase
BK054_RS16965	COG3340	Belongs to the peptidase S51 family
BK054_RS16970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BK054_RS16975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BK054_RS16980	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BK054_RS16985	COG0440	acetolactate synthase activity
BK054_RS16990	COG0028	Belongs to the TPP enzyme family
BK054_RS16995	COG0129	dihydroxy-acid dehydratase activity
BK054_RS17010	COG1280	lysine exporter protein (LysE YggA)
BK054_RS17015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK054_RS17020	COG0697	spore germination
BK054_RS17030	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BK054_RS17035	COG1132	(ABC) transporter
BK054_RS17040	COG1132	(ABC) transporter
BK054_RS17040	COG2375	cellular response to nickel ion
BK054_RS17070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK054_RS17075	COG0697	spore germination
BK054_RS17095	COG4607	ABC-type enterochelin transport system periplasmic component
BK054_RS17100	COG4574	serine-type endopeptidase inhibitor activity
BK054_RS17105	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BK054_RS17130	COG0745	RESPONSE REGULATOR receiver
BK054_RS17150	COG0488	(ABC) transporter
BK054_RS17195	COG0456	acetyltransferase
BK054_RS17200	COG4585	Histidine kinase
BK054_RS17210	COG2197	response regulator
BK054_RS17300	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BK054_RS17345	COG1741	Belongs to the pirin family
BK054_RS17365	COG2076	Multidrug Resistance protein
BK054_RS17400	COG2365	Tyrosine phosphatase family
BK054_RS17405	COG0753	catalase activity
BK054_RS17415	COG4585	Histidine kinase
BK054_RS17420	COG0415	Belongs to the DNA photolyase family
BK054_RS17425	COG0471	metal ion transport
BK054_RS17435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BK054_RS17440	COG1053	succinate dehydrogenase
BK054_RS17455	COG0477	Major facilitator Superfamily
BK054_RS17460	COG0512	Glutamine amidotransferase of anthranilate synthase
BK054_RS17465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BK054_RS17470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BK054_RS17495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BK054_RS17510	COG1045	serine acetyltransferase
BK054_RS17520	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BK054_RS17535	COG1757	Na H antiporter
BK054_RS17540	COG0517	IMP dehydrogenase activity
BK054_RS17540	COG0516	GMP reductase activity
BK054_RS17550	COG1280	lysine exporter protein (LysE YggA)
BK054_RS17555	COG0167	dihydroorotate dehydrogenase activity
BK054_RS17565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BK054_RS17570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BK054_RS17595	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BK054_RS17595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BK054_RS17625	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BK054_RS17630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BK054_RS17640	COG0742	ribosomal rna small subunit methyltransferase
BK054_RS17665	COG0861	Integral membrane protein TerC family
BK054_RS17675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BK054_RS17700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BK054_RS17700	COG1333	cytochrome c biogenesis protein
BK054_RS17710	COG2885	chlorophyll binding
BK054_RS17740	COG2197	response regulator
BK054_RS17745	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BK054_RS17745	COG0140	phosphoribosyl-ATP diphosphatase activity
BK054_RS17750	COG0107	imidazoleglycerol-phosphate synthase activity
BK054_RS17755	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BK054_RS17765	COG0131	Imidazoleglycerol-phosphate dehydratase
BK054_RS17765	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BK054_RS17770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BK054_RS17775	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BK054_RS17780	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BK054_RS17795	COG0006	proline dipeptidase activity
BK054_RS17845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BK054_RS17910	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BK054_RS17920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BK054_RS17935	COG0601	transmembrane transport
BK054_RS17945	COG0149	triose-phosphate isomerase activity
BK054_RS17960	COG2197	response regulator
BK054_RS18005	COG0798	PFAM Bile acid sodium symporter
BK054_RS18020	COG1943	Transposase
BK054_RS18025	COG1012	belongs to the aldehyde dehydrogenase family
BK054_RS18045	COG2890	protein-(glutamine-N5) methyltransferase activity
BK054_RS18050	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BK054_RS18050	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BK054_RS18055	COG1739	Uncharacterized protein family UPF0029