locus-tag	class	description
MFUL124B02_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MFUL124B02_RS00050	COG2814	Major facilitator Superfamily
MFUL124B02_RS00060	COG2259	Doxx family
MFUL124B02_RS00075	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MFUL124B02_RS00085	COG0189	ligase activity
MFUL124B02_RS00090	COG2815	serine threonine protein kinase
MFUL124B02_RS00090	COG0515	serine threonine protein kinase
MFUL124B02_RS00130	COG0515	serine threonine protein kinase
MFUL124B02_RS00145	COG0557	exoribonuclease II activity
MFUL124B02_RS00190	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFUL124B02_RS00195	COG1063	alcohol dehydrogenase
MFUL124B02_RS00205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFUL124B02_RS00220	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MFUL124B02_RS00245	COG2274	protein secretion by the type I secretion system
MFUL124B02_RS00250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFUL124B02_RS00250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFUL124B02_RS00265	COG3311	Transcriptional regulator
MFUL124B02_RS00280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MFUL124B02_RS00310	COG1063	alcohol dehydrogenase
MFUL124B02_RS00315	COG3387	PFAM Glycoside hydrolase 15-related
MFUL124B02_RS00340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MFUL124B02_RS00375	COG1690	Belongs to the RtcB family
MFUL124B02_RS00400	COG0515	serine threonine protein kinase
MFUL124B02_RS00420	COG0402	S-adenosylhomocysteine deaminase activity
MFUL124B02_RS00460	COG1309	transcriptional regulator
MFUL124B02_RS00485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MFUL124B02_RS00500	COG2814	Major facilitator Superfamily
MFUL124B02_RS00540	COG2226	methyltransferase
MFUL124B02_RS00565	COG0477	Major facilitator Superfamily
MFUL124B02_RS00575	COG1104	cysteine desulfurase activity
MFUL124B02_RS00580	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS00580	COG1136	(ABC) transporter
MFUL124B02_RS00585	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS00625	COG2204	response regulator
MFUL124B02_RS00630	COG0515	serine threonine protein kinase
MFUL124B02_RS00640	COG1012	belongs to the aldehyde dehydrogenase family
MFUL124B02_RS00645	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
MFUL124B02_RS00645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MFUL124B02_RS00655	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MFUL124B02_RS00715	COG0038	chloride channel
MFUL124B02_RS00735	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MFUL124B02_RS00740	COG3781	membrane
MFUL124B02_RS00795	COG4717	serine-type aminopeptidase activity
MFUL124B02_RS00800	COG0420	3'-5' exonuclease activity
MFUL124B02_RS00835	COG4191	Histidine kinase
MFUL124B02_RS00910	COG0640	Transcriptional regulator
MFUL124B02_RS00935	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MFUL124B02_RS00940	COG2205	protein histidine kinase activity
MFUL124B02_RS00945	COG5002	protein histidine kinase activity
MFUL124B02_RS00990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MFUL124B02_RS00995	COG3268	Saccharopine dehydrogenase
MFUL124B02_RS01005	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MFUL124B02_RS01015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MFUL124B02_RS01020	COG3453	Protein conserved in bacteria
MFUL124B02_RS01020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MFUL124B02_RS01030	COG0446	pyridine nucleotide-disulphide oxidoreductase
MFUL124B02_RS01045	COG1285	pathogenesis
MFUL124B02_RS01110	COG2304	oxidoreductase activity
MFUL124B02_RS01135	COG5002	protein histidine kinase activity
MFUL124B02_RS01140	COG5002	protein histidine kinase activity
MFUL124B02_RS01145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MFUL124B02_RS01155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MFUL124B02_RS01160	COG0697	spore germination
MFUL124B02_RS01165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MFUL124B02_RS01190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MFUL124B02_RS01210	COG1196	nuclear chromosome segregation
MFUL124B02_RS01210	COG0741	lytic transglycosylase activity
MFUL124B02_RS01210	COG0739	heme binding
MFUL124B02_RS01215	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS01220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MFUL124B02_RS01225	COG1522	sequence-specific DNA binding
MFUL124B02_RS01265	COG1309	transcriptional regulator
MFUL124B02_RS01270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFUL124B02_RS01275	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS01325	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS01330	COG2205	protein histidine kinase activity
MFUL124B02_RS01340	COG0840	transmembrane signaling receptor activity
MFUL124B02_RS01350	COG2205	protein histidine kinase activity
MFUL124B02_RS01350	COG0784	Response regulator, receiver
MFUL124B02_RS01350	COG2198	Histidine kinase
MFUL124B02_RS01355	COG0784	Response regulator, receiver
MFUL124B02_RS01355	COG2198	Histidine kinase
MFUL124B02_RS01355	COG2205	protein histidine kinase activity
MFUL124B02_RS01415	COG4335	DNA alkylation repair
MFUL124B02_RS01420	COG0784	Response regulator, receiver
MFUL124B02_RS01420	COG2205	protein histidine kinase activity
MFUL124B02_RS01425	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MFUL124B02_RS01440	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MFUL124B02_RS01445	COG1127	ABC transporter
MFUL124B02_RS01455	COG2124	cytochrome p450
MFUL124B02_RS01465	COG2124	cytochrome p450
MFUL124B02_RS01470	COG2124	cytochrome p450
MFUL124B02_RS01485	COG0189	ligase activity
MFUL124B02_RS01485	COG4067	protein conserved in archaea
MFUL124B02_RS01520	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS01525	COG0475	glutathione-regulated potassium exporter activity
MFUL124B02_RS01530	COG1396	sequence-specific DNA binding
MFUL124B02_RS01555	COG2808	Putative FMN-binding domain
MFUL124B02_RS01570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MFUL124B02_RS01615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MFUL124B02_RS01620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MFUL124B02_RS01625	COG1690	Belongs to the RtcB family
MFUL124B02_RS01655	COG0247	lactate metabolic process
MFUL124B02_RS01655	COG2181	nitrate reductase activity
MFUL124B02_RS01685	COG0477	Major facilitator Superfamily
MFUL124B02_RS01700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS01705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS01725	COG1819	glycosyl
MFUL124B02_RS01735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MFUL124B02_RS01740	COG0667	Aldo Keto reductase
MFUL124B02_RS01745	COG3850	Histidine kinase
MFUL124B02_RS01745	COG4999	Histidine kinase
MFUL124B02_RS01745	COG2205	protein histidine kinase activity
MFUL124B02_RS01745	COG3437	response regulator, receiver
MFUL124B02_RS01785	COG2197	response regulator
MFUL124B02_RS01810	COG4948	Mandelate Racemase Muconate Lactonizing
MFUL124B02_RS01840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MFUL124B02_RS01845	COG0628	permease
MFUL124B02_RS01890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MFUL124B02_RS01895	COG2885	chlorophyll binding
MFUL124B02_RS01905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFUL124B02_RS01905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFUL124B02_RS01910	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS01925	COG2267	carboxylic ester hydrolase activity
MFUL124B02_RS01930	COG1131	(ABC) transporter
MFUL124B02_RS01990	COG4946	Tricorn protease homolog
MFUL124B02_RS01990	COG1506	peptidase
MFUL124B02_RS01990	COG0823	Involved in the tonB-independent uptake of proteins
MFUL124B02_RS02005	COG5002	protein histidine kinase activity
MFUL124B02_RS02010	COG3158	transport of potassium into the cell
MFUL124B02_RS02040	COG0823	Involved in the tonB-independent uptake of proteins
MFUL124B02_RS02045	COG5002	protein histidine kinase activity
MFUL124B02_RS02070	COG0189	ligase activity
MFUL124B02_RS02105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MFUL124B02_RS02155	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MFUL124B02_RS02160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MFUL124B02_RS02165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MFUL124B02_RS02175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MFUL124B02_RS02185	COG3279	Response regulator of the LytR AlgR family
MFUL124B02_RS02190	COG3275	phosphorelay sensor kinase activity
MFUL124B02_RS02195	COG0596	Alpha beta hydrolase
MFUL124B02_RS02200	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
MFUL124B02_RS02225	COG2239	Acts as a magnesium transporter
MFUL124B02_RS02310	COG1250	3-hydroxyacyl-CoA dehydrogenase
MFUL124B02_RS02315	COG0183	Belongs to the thiolase family
MFUL124B02_RS02345	COG0559	Belongs to the binding-protein-dependent transport system permease family
MFUL124B02_RS02370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MFUL124B02_RS02375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MFUL124B02_RS02380	COG0515	serine threonine protein kinase
MFUL124B02_RS02390	COG4191	Histidine kinase
MFUL124B02_RS02395	COG1881	PFAM PEBP family protein
MFUL124B02_RS02410	COG0356	it plays a direct role in the translocation of protons across the membrane
MFUL124B02_RS02415	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFUL124B02_RS02420	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MFUL124B02_RS02425	COG0012	GTP binding
MFUL124B02_RS02455	COG0372	Belongs to the citrate synthase family
MFUL124B02_RS02460	COG2226	methyltransferase
MFUL124B02_RS02510	COG1408	metallophosphoesterase
MFUL124B02_RS02515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MFUL124B02_RS02565	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS02590	COG0667	Aldo Keto reductase
MFUL124B02_RS02610	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MFUL124B02_RS02640	COG2258	MOSC domain
MFUL124B02_RS02680	COG2124	cytochrome p450
MFUL124B02_RS02740	COG1272	protein, Hemolysin III
MFUL124B02_RS02760	COG4191	Histidine kinase
MFUL124B02_RS02765	COG2204	response regulator
MFUL124B02_RS02770	COG3852	Histidine kinase
MFUL124B02_RS02790	COG0534	Mate efflux family protein
MFUL124B02_RS02800	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MFUL124B02_RS02805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MFUL124B02_RS02810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MFUL124B02_RS02825	COG2827	Endonuclease containing a URI domain
MFUL124B02_RS02850	COG0602	queuosine metabolic process
MFUL124B02_RS02860	COG2816	NAD+ diphosphatase activity
MFUL124B02_RS02870	COG0346	lactoylglutathione lyase activity
MFUL124B02_RS02885	COG2070	2-Nitropropane dioxygenase
MFUL124B02_RS02895	COG4771	TonB-dependent receptor
MFUL124B02_RS02905	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MFUL124B02_RS02905	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MFUL124B02_RS02930	COG2815	serine threonine protein kinase
MFUL124B02_RS02930	COG0515	serine threonine protein kinase
MFUL124B02_RS02975	COG0436	Aminotransferase
MFUL124B02_RS03005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFUL124B02_RS03005	COG0551	DNA topoisomerase type I activity
MFUL124B02_RS03015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFUL124B02_RS03030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MFUL124B02_RS03040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MFUL124B02_RS03050	COG2272	Belongs to the type-B carboxylesterase lipase family
MFUL124B02_RS03055	COG0515	serine threonine protein kinase
MFUL124B02_RS03060	COG0842	Transport permease protein
MFUL124B02_RS03065	COG1131	(ABC) transporter
MFUL124B02_RS03075	COG0488	(ABC) transporter
MFUL124B02_RS03085	COG3584	3D domain protein
MFUL124B02_RS03085	COG1388	LysM domain
MFUL124B02_RS03110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MFUL124B02_RS03145	COG2205	protein histidine kinase activity
MFUL124B02_RS03160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFUL124B02_RS03260	COG2205	protein histidine kinase activity
MFUL124B02_RS03265	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS03295	COG1125	glycine betaine transport
MFUL124B02_RS03295	COG0517	IMP dehydrogenase activity
MFUL124B02_RS03305	COG1612	heme a metabolic process
MFUL124B02_RS03305	COG0109	protoheme IX farnesyltransferase activity
MFUL124B02_RS03380	COG0671	phosphoesterase, PA-phosphatase related
MFUL124B02_RS03390	COG0110	maltose O-acetyltransferase activity
MFUL124B02_RS03395	COG4191	Histidine kinase
MFUL124B02_RS03475	COG1793	dna ligase
MFUL124B02_RS03485	COG3265	gluconokinase activity
MFUL124B02_RS03490	COG1335	isochorismatase
MFUL124B02_RS03500	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS03550	COG0488	(ABC) transporter
MFUL124B02_RS03565	COG1309	transcriptional regulator
MFUL124B02_RS03575	COG0625	glutathione transferase activity
MFUL124B02_RS03605	COG1192	Involved in chromosome partitioning
MFUL124B02_RS03615	COG4783	chaperone-mediated protein folding
MFUL124B02_RS03625	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MFUL124B02_RS03665	COG5002	protein histidine kinase activity
MFUL124B02_RS03670	COG0308	aminopeptidase N
MFUL124B02_RS03675	COG0484	heat shock protein binding
MFUL124B02_RS03705	COG1764	response to oxidative stress
MFUL124B02_RS03740	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MFUL124B02_RS03750	COG0596	Alpha beta hydrolase
MFUL124B02_RS03760	COG1234	tRNA 3'-trailer cleavage
MFUL124B02_RS03770	COG1309	transcriptional regulator
MFUL124B02_RS03800	COG1051	belongs to the nudix hydrolase family
MFUL124B02_RS03815	COG1278	Cold shock
MFUL124B02_RS03825	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
MFUL124B02_RS03900	COG2031	fatty acid transporter
MFUL124B02_RS03905	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MFUL124B02_RS03910	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS03920	COG2205	protein histidine kinase activity
MFUL124B02_RS03920	COG3437	response regulator, receiver
MFUL124B02_RS03920	COG3850	Histidine kinase
MFUL124B02_RS03920	COG4999	Histidine kinase
MFUL124B02_RS03925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MFUL124B02_RS03960	COG0656	L-ascorbic acid biosynthetic process
MFUL124B02_RS03965	COG5002	protein histidine kinase activity
MFUL124B02_RS03985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MFUL124B02_RS03990	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS03995	COG2205	protein histidine kinase activity
MFUL124B02_RS04010	COG3483	tryptophan 2,3-dioxygenase activity
MFUL124B02_RS04020	COG3437	response regulator, receiver
MFUL124B02_RS04020	COG2205	protein histidine kinase activity
MFUL124B02_RS04020	COG3850	Histidine kinase
MFUL124B02_RS04020	COG4999	Histidine kinase
MFUL124B02_RS04035	COG5002	protein histidine kinase activity
MFUL124B02_RS04040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MFUL124B02_RS04095	COG1132	(ABC) transporter
MFUL124B02_RS04105	COG0484	heat shock protein binding
MFUL124B02_RS04150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MFUL124B02_RS04205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFUL124B02_RS04225	COG3842	ATPase activity
MFUL124B02_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS04255	COG0789	Transcriptional regulator
MFUL124B02_RS04265	COG0330	HflC and HflK could
MFUL124B02_RS04270	COG0616	signal peptide processing
MFUL124B02_RS04285	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MFUL124B02_RS04290	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS04315	COG0612	Peptidase, M16
MFUL124B02_RS04345	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS04365	COG0840	transmembrane signaling receptor activity
MFUL124B02_RS04380	COG3938	Belongs to the proline racemase family
MFUL124B02_RS04385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MFUL124B02_RS04400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MFUL124B02_RS04420	COG3291	Pkd domain containing protein
MFUL124B02_RS04470	COG4251	negative regulation of phosphorylation
MFUL124B02_RS04490	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS04510	COG2814	Major facilitator Superfamily
MFUL124B02_RS04515	COG0679	Auxin Efflux Carrier
MFUL124B02_RS04610	COG1131	(ABC) transporter
MFUL124B02_RS04650	COG0300	oxidoreductase activity
MFUL124B02_RS04720	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MFUL124B02_RS04730	COG0804	urea catabolic process
MFUL124B02_RS04735	COG0831	urea catabolic process
MFUL124B02_RS04735	COG0832	Belongs to the urease beta subunit family
MFUL124B02_RS04740	COG0829	nickel cation binding
MFUL124B02_RS04745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MFUL124B02_RS04750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MFUL124B02_RS04760	COG1309	transcriptional regulator
MFUL124B02_RS04800	COG0243	molybdopterin cofactor binding
MFUL124B02_RS04810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFUL124B02_RS04825	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MFUL124B02_RS04850	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS04870	COG3025	triphosphatase activity
MFUL124B02_RS04870	COG5607	PFAM CHAD domain containing protein
MFUL124B02_RS04875	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MFUL124B02_RS04910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MFUL124B02_RS04915	COG0625	glutathione transferase activity
MFUL124B02_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS04925	COG0783	Belongs to the Dps family
MFUL124B02_RS04970	COG0625	glutathione transferase activity
MFUL124B02_RS05020	COG2819	hydrolase of the alpha beta superfamily
MFUL124B02_RS05050	COG1309	transcriptional regulator
MFUL124B02_RS05065	COG1408	metallophosphoesterase
MFUL124B02_RS05100	COG2819	hydrolase of the alpha beta superfamily
MFUL124B02_RS05110	COG1090	epimerase
MFUL124B02_RS05120	COG0142	geranyltranstransferase activity
MFUL124B02_RS05130	COG1562	ergosterol biosynthetic process
MFUL124B02_RS05185	COG2815	serine threonine protein kinase
MFUL124B02_RS05185	COG0515	serine threonine protein kinase
MFUL124B02_RS05190	COG2204	response regulator
MFUL124B02_RS05215	COG0174	glutamine synthetase
MFUL124B02_RS05230	COG0640	Transcriptional regulator
MFUL124B02_RS05250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MFUL124B02_RS05255	COG3844	kynureninase activity
MFUL124B02_RS05280	COG5002	protein histidine kinase activity
MFUL124B02_RS05325	COG0515	serine threonine protein kinase
MFUL124B02_RS05350	COG2815	serine threonine protein kinase
MFUL124B02_RS05350	COG0515	serine threonine protein kinase
MFUL124B02_RS05360	COG5507	3-demethylubiquinone-9 3-methyltransferase
MFUL124B02_RS05365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS05370	COG2204	response regulator
MFUL124B02_RS05375	COG0392	lysyltransferase activity
MFUL124B02_RS05410	COG2204	response regulator
MFUL124B02_RS05425	COG4206	TonB-dependent receptor
MFUL124B02_RS05430	COG2192	nodulation
MFUL124B02_RS05440	COG1492	cobalamin metabolic process
MFUL124B02_RS05445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MFUL124B02_RS05450	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MFUL124B02_RS05455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFUL124B02_RS05460	COG2124	cytochrome p450
MFUL124B02_RS05465	COG0406	alpha-ribazole phosphatase activity
MFUL124B02_RS05470	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MFUL124B02_RS05475	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MFUL124B02_RS05490	COG1846	Transcriptional regulator
MFUL124B02_RS05500	COG2814	Major facilitator Superfamily
MFUL124B02_RS05545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MFUL124B02_RS05570	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFUL124B02_RS05575	COG0363	glucosamine-6-phosphate deaminase activity
MFUL124B02_RS05580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MFUL124B02_RS05590	COG0204	Acyl-transferase
MFUL124B02_RS05610	COG0420	3'-5' exonuclease activity
MFUL124B02_RS05645	COG2267	carboxylic ester hydrolase activity
MFUL124B02_RS05655	COG3852	Histidine kinase
MFUL124B02_RS05665	COG1464	Belongs to the NlpA lipoprotein family
MFUL124B02_RS05670	COG2011	ABC-type metal ion transport system permease component
MFUL124B02_RS05675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MFUL124B02_RS05680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MFUL124B02_RS05685	COG0626	cystathionine gamma-synthase activity
MFUL124B02_RS05690	COG0626	cystathionine gamma-synthase activity
MFUL124B02_RS05695	COG0460	homoserine dehydrogenase
MFUL124B02_RS05695	COG0527	aspartate kinase activity
MFUL124B02_RS05765	COG3436	PFAM IS66 Orf2 family protein
MFUL124B02_RS05775	COG2433	Pfam Transposase IS66
MFUL124B02_RS05790	COG2226	methyltransferase
MFUL124B02_RS05795	COG0789	Transcriptional regulator
MFUL124B02_RS05805	COG4104	PAAR repeat-containing protein
MFUL124B02_RS05805	COG3209	COG3209 Rhs family protein
MFUL124B02_RS05805	COG3209	COG3209 Rhs family protein
MFUL124B02_RS05805	COG4104	PAAR repeat-containing protein
MFUL124B02_RS05830	COG3023	N-Acetylmuramoyl-L-alanine amidase
MFUL124B02_RS05840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFUL124B02_RS05860	COG2205	protein histidine kinase activity
MFUL124B02_RS05880	COG1201	RNA secondary structure unwinding
MFUL124B02_RS05885	COG1404	Belongs to the peptidase S8 family
MFUL124B02_RS05900	COG2322	membrane
MFUL124B02_RS05935	COG0697	spore germination
MFUL124B02_RS05965	COG0402	S-adenosylhomocysteine deaminase activity
MFUL124B02_RS05990	COG5002	protein histidine kinase activity
MFUL124B02_RS06035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MFUL124B02_RS06040	COG0489	protein tyrosine kinase activity
MFUL124B02_RS06045	COG0297	glycogen (starch) synthase activity
MFUL124B02_RS06050	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS06065	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS06070	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS06080	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS06105	COG1215	transferase activity, transferring glycosyl groups
MFUL124B02_RS06110	COG1940	carbohydrate kinase activity
MFUL124B02_RS06145	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MFUL124B02_RS06145	COG2755	lipolytic protein G-D-S-L family
MFUL124B02_RS06150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MFUL124B02_RS06190	COG3724	N-succinylarginine dihydrolase activity
MFUL124B02_RS06195	COG1560	Kdo2-lipid A biosynthetic process
MFUL124B02_RS06210	COG1137	ATPase activity
MFUL124B02_RS06230	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS06235	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MFUL124B02_RS06245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MFUL124B02_RS06255	COG1490	D-aminoacyl-tRNA deacylase activity
MFUL124B02_RS06265	COG0629	single-stranded DNA binding
MFUL124B02_RS06270	COG2009	succinate dehydrogenase
MFUL124B02_RS06275	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MFUL124B02_RS06285	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MFUL124B02_RS06295	COG4191	Histidine kinase
MFUL124B02_RS06300	COG2204	response regulator
MFUL124B02_RS06310	COG1007	ATP synthesis coupled electron transport
MFUL124B02_RS06325	COG0713	ATP synthesis coupled electron transport
MFUL124B02_RS06330	COG0839	Belongs to the complex I subunit 6 family
MFUL124B02_RS06340	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MFUL124B02_RS06345	COG0784	Response regulator, receiver
MFUL124B02_RS06350	COG0515	serine threonine protein kinase
MFUL124B02_RS06350	COG2815	serine threonine protein kinase
MFUL124B02_RS06355	COG0560	Phosphoserine phosphatase
MFUL124B02_RS06355	COG3830	Belongs to the UPF0237 family
MFUL124B02_RS06370	COG0071	Belongs to the small heat shock protein (HSP20) family
MFUL124B02_RS06380	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MFUL124B02_RS06385	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MFUL124B02_RS06390	COG0504	CTP synthase activity
MFUL124B02_RS06400	COG1132	(ABC) transporter
MFUL124B02_RS06405	COG0656	L-ascorbic acid biosynthetic process
MFUL124B02_RS06410	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MFUL124B02_RS06420	COG0564	pseudouridine synthase activity
MFUL124B02_RS06425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MFUL124B02_RS06435	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS06440	COG1534	Rna-binding protein
MFUL124B02_RS06445	COG0484	heat shock protein binding
MFUL124B02_RS06500	COG5016	pyruvate
MFUL124B02_RS06500	COG0511	ligase activity, forming carbon-carbon bonds
MFUL124B02_RS06505	COG0439	Biotin carboxylase
MFUL124B02_RS06515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MFUL124B02_RS06545	COG2264	protein methyltransferase activity
MFUL124B02_RS06570	COG2204	response regulator
MFUL124B02_RS06575	COG4191	Histidine kinase
MFUL124B02_RS06595	COG1714	RDD family
MFUL124B02_RS06605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MFUL124B02_RS06610	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MFUL124B02_RS06640	COG2264	protein methyltransferase activity
MFUL124B02_RS06665	COG2226	methyltransferase
MFUL124B02_RS06670	COG0612	Peptidase, M16
MFUL124B02_RS06680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MFUL124B02_RS06745	COG0719	Fe-S assembly protein
MFUL124B02_RS06750	COG0396	ATPase activity
MFUL124B02_RS06755	COG0719	Fe-S assembly protein
MFUL124B02_RS06765	COG0822	iron-sulfur transferase activity
MFUL124B02_RS06770	COG2151	metal-sulfur cluster biosynthetic enzyme
MFUL124B02_RS06775	COG0693	protein deglycase activity
MFUL124B02_RS06780	COG1446	asparaginase
MFUL124B02_RS06815	COG0515	serine threonine protein kinase
MFUL124B02_RS06815	COG2815	serine threonine protein kinase
MFUL124B02_RS06835	COG4191	Histidine kinase
MFUL124B02_RS06840	COG2204	response regulator
MFUL124B02_RS06855	COG1376	ErfK ybiS ycfS ynhG family protein
MFUL124B02_RS06860	COG0432	Pfam Uncharacterised protein family UPF0047
MFUL124B02_RS06910	COG2130	NADP-dependent
MFUL124B02_RS06950	COG2204	response regulator
MFUL124B02_RS06955	COG5000	phosphorelay sensor kinase activity
MFUL124B02_RS07000	COG0308	aminopeptidase N
MFUL124B02_RS07010	COG1040	competence protein
MFUL124B02_RS07015	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MFUL124B02_RS07020	COG1690	Belongs to the RtcB family
MFUL124B02_RS07025	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MFUL124B02_RS07075	COG3852	Histidine kinase
MFUL124B02_RS07085	COG3409	Peptidoglycan-binding domain 1 protein
MFUL124B02_RS07090	COG2261	transglycosylase associated protein
MFUL124B02_RS07110	COG1272	protein, Hemolysin III
MFUL124B02_RS07115	COG1366	Belongs to the anti-sigma-factor antagonist family
MFUL124B02_RS07130	COG1733	regulation of RNA biosynthetic process
MFUL124B02_RS07135	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MFUL124B02_RS07145	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MFUL124B02_RS07150	COG0156	8-amino-7-oxononanoate synthase activity
MFUL124B02_RS07155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MFUL124B02_RS07165	COG0436	Aminotransferase
MFUL124B02_RS07180	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MFUL124B02_RS07185	COG0471	metal ion transport
MFUL124B02_RS07185	COG3273	potassium ion transport
MFUL124B02_RS07215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MFUL124B02_RS07225	COG2155	Conserved Protein
MFUL124B02_RS07250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MFUL124B02_RS07265	COG0823	Involved in the tonB-independent uptake of proteins
MFUL124B02_RS07270	COG3279	Response regulator of the LytR AlgR family
MFUL124B02_RS07275	COG3275	phosphorelay sensor kinase activity
MFUL124B02_RS07295	COG0297	glycogen (starch) synthase activity
MFUL124B02_RS07300	COG2815	serine threonine protein kinase
MFUL124B02_RS07300	COG0515	serine threonine protein kinase
MFUL124B02_RS07335	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MFUL124B02_RS07355	COG4771	TonB-dependent receptor
MFUL124B02_RS07365	COG3720	iron ion transport
MFUL124B02_RS07370	COG4558	Periplasmic binding protein
MFUL124B02_RS07375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFUL124B02_RS07380	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MFUL124B02_RS07515	COG1228	amidohydrolase
MFUL124B02_RS07530	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS07535	COG5002	protein histidine kinase activity
MFUL124B02_RS07555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MFUL124B02_RS07560	COG2814	Major facilitator Superfamily
MFUL124B02_RS07565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MFUL124B02_RS07570	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MFUL124B02_RS07575	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS07585	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MFUL124B02_RS07590	COG0189	ligase activity
MFUL124B02_RS07595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MFUL124B02_RS07600	COG3959	Transketolase, thiamine diphosphate binding domain
MFUL124B02_RS07610	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS07610	COG0300	oxidoreductase activity
MFUL124B02_RS07610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MFUL124B02_RS07610	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS07610	COG3321	synthase
MFUL124B02_RS07645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MFUL124B02_RS07670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFUL124B02_RS07675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFUL124B02_RS07680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MFUL124B02_RS07685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MFUL124B02_RS07710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MFUL124B02_RS07715	COG2353	YceI-like domain
MFUL124B02_RS07720	COG1741	Belongs to the pirin family
MFUL124B02_RS07740	COG1131	(ABC) transporter
MFUL124B02_RS07770	COG0405	Gamma-glutamyltransferase
MFUL124B02_RS07775	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MFUL124B02_RS07780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MFUL124B02_RS07795	COG3540	Alkaline phosphatase
MFUL124B02_RS07810	COG2183	response to ionizing radiation
MFUL124B02_RS07830	COG0326	Molecular chaperone. Has ATPase activity
MFUL124B02_RS07835	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MFUL124B02_RS07865	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MFUL124B02_RS07870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MFUL124B02_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS07930	COG0840	transmembrane signaling receptor activity
MFUL124B02_RS07940	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS07970	COG0564	pseudouridine synthase activity
MFUL124B02_RS07975	COG1215	transferase activity, transferring glycosyl groups
MFUL124B02_RS07995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MFUL124B02_RS08010	COG0625	glutathione transferase activity
MFUL124B02_RS08020	COG4585	Histidine kinase
MFUL124B02_RS08025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFUL124B02_RS08035	COG0242	peptide deformylase activity
MFUL124B02_RS08040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MFUL124B02_RS08050	COG0739	heme binding
MFUL124B02_RS08055	COG0776	regulation of translation
MFUL124B02_RS08070	COG1183	phosphatidylcholine synthase activity
MFUL124B02_RS08075	COG1058	Belongs to the CinA family
MFUL124B02_RS08075	COG1546	Belongs to the CinA family
MFUL124B02_RS08095	COG1252	NADH dehydrogenase
MFUL124B02_RS08100	COG0606	chelatase, subunit chli
MFUL124B02_RS08170	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MFUL124B02_RS08175	COG0116	Belongs to the methyltransferase superfamily
MFUL124B02_RS08175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MFUL124B02_RS08195	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFUL124B02_RS08200	COG0154	amidase activity
MFUL124B02_RS08205	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFUL124B02_RS08235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MFUL124B02_RS08240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MFUL124B02_RS08245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MFUL124B02_RS08270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MFUL124B02_RS08280	COG1666	GTP binding
MFUL124B02_RS08285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFUL124B02_RS08295	COG0515	serine threonine protein kinase
MFUL124B02_RS08310	COG0542	response to heat
MFUL124B02_RS08380	COG0569	domain protein
MFUL124B02_RS08385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MFUL124B02_RS08390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MFUL124B02_RS08395	COG1714	RDD family
MFUL124B02_RS08590	COG4653	Phage capsid family
MFUL124B02_RS08600	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MFUL124B02_RS08625	COG5518	Phage portal protein
MFUL124B02_RS08650	COG4974	Belongs to the 'phage' integrase family
MFUL124B02_RS08670	COG2176	DNA-directed DNA polymerase activity
MFUL124B02_RS08740	COG0515	serine threonine protein kinase
MFUL124B02_RS08755	COG0515	serine threonine protein kinase
MFUL124B02_RS08760	COG4584	PFAM Integrase catalytic
MFUL124B02_RS08765	COG1484	DNA-dependent DNA replication
MFUL124B02_RS08865	COG3279	Response regulator of the LytR AlgR family
MFUL124B02_RS08875	COG2267	carboxylic ester hydrolase activity
MFUL124B02_RS08900	COG0625	glutathione transferase activity
MFUL124B02_RS08915	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS08955	COG1515	deoxyribonuclease V activity
MFUL124B02_RS08985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MFUL124B02_RS09030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MFUL124B02_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS09040	COG1690	Belongs to the RtcB family
MFUL124B02_RS09055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MFUL124B02_RS09065	COG0477	Major facilitator Superfamily
MFUL124B02_RS09070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MFUL124B02_RS09075	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS09115	COG2967	ApaG domain
MFUL124B02_RS09135	COG0009	L-threonylcarbamoyladenylate synthase
MFUL124B02_RS09140	COG1090	epimerase
MFUL124B02_RS09145	COG1131	(ABC) transporter
MFUL124B02_RS09175	COG2205	protein histidine kinase activity
MFUL124B02_RS09175	COG2202	Pas domain
MFUL124B02_RS09180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MFUL124B02_RS09180	COG0723	plastoquinol--plastocyanin reductase activity
MFUL124B02_RS09190	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MFUL124B02_RS09215	COG2814	Major facilitator Superfamily
MFUL124B02_RS09225	COG2264	protein methyltransferase activity
MFUL124B02_RS09245	COG0783	Belongs to the Dps family
MFUL124B02_RS09255	COG0450	alkyl hydroperoxide reductase
MFUL124B02_RS09280	COG0625	glutathione transferase activity
MFUL124B02_RS09300	COG1741	Belongs to the pirin family
MFUL124B02_RS09315	COG1902	pentaerythritol trinitrate reductase activity
MFUL124B02_RS09395	COG1228	amidohydrolase
MFUL124B02_RS09425	COG1595	DNA-templated transcription, initiation
MFUL124B02_RS09465	COG0765	amino acid transport
MFUL124B02_RS09470	COG1126	abc transporter atp-binding protein
MFUL124B02_RS09495	COG5002	protein histidine kinase activity
MFUL124B02_RS09500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MFUL124B02_RS09505	COG1984	allophanate hydrolase subunit 2
MFUL124B02_RS09510	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MFUL124B02_RS09520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MFUL124B02_RS09530	COG1045	serine acetyltransferase
MFUL124B02_RS09535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MFUL124B02_RS09540	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS09565	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS09570	COG0477	Major facilitator Superfamily
MFUL124B02_RS09575	COG2815	serine threonine protein kinase
MFUL124B02_RS09575	COG0515	serine threonine protein kinase
MFUL124B02_RS09585	COG1238	metal cluster binding
MFUL124B02_RS09600	COG0628	permease
MFUL124B02_RS09615	COG1187	pseudouridine synthase activity
MFUL124B02_RS09635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MFUL124B02_RS09670	COG1131	(ABC) transporter
MFUL124B02_RS09680	COG2264	protein methyltransferase activity
MFUL124B02_RS09685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MFUL124B02_RS09690	COG3584	3D domain protein
MFUL124B02_RS09690	COG1388	LysM domain
MFUL124B02_RS09790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MFUL124B02_RS09805	COG1278	Cold shock
MFUL124B02_RS09815	COG1278	Cold shock
MFUL124B02_RS09820	COG1131	(ABC) transporter
MFUL124B02_RS09830	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS09835	COG2378	regulation of single-species biofilm formation
MFUL124B02_RS09865	COG2376	Dihydroxyacetone kinase
MFUL124B02_RS09900	COG3275	phosphorelay sensor kinase activity
MFUL124B02_RS09905	COG3279	Response regulator of the LytR AlgR family
MFUL124B02_RS09995	COG0076	glutamate decarboxylase activity
MFUL124B02_RS10015	COG0477	Major facilitator Superfamily
MFUL124B02_RS10025	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MFUL124B02_RS10050	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS10090	COG0251	oxidation-reduction process
MFUL124B02_RS10110	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS10125	COG1595	DNA-templated transcription, initiation
MFUL124B02_RS10155	COG3279	Response regulator of the LytR AlgR family
MFUL124B02_RS10160	COG3275	phosphorelay sensor kinase activity
MFUL124B02_RS10165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MFUL124B02_RS10180	COG2937	Belongs to the GPAT DAPAT family
MFUL124B02_RS10185	COG0277	FAD linked oxidase domain protein
MFUL124B02_RS10190	COG1309	transcriptional regulator
MFUL124B02_RS10220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MFUL124B02_RS10260	COG0501	Belongs to the peptidase M48B family
MFUL124B02_RS10295	COG0640	Transcriptional regulator
MFUL124B02_RS10315	COG3321	synthase
MFUL124B02_RS10315	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS10315	COG0604	alcohol dehydrogenase
MFUL124B02_RS10325	COG3321	synthase
MFUL124B02_RS10325	COG0604	alcohol dehydrogenase
MFUL124B02_RS10360	COG1643	Atp-dependent helicase
MFUL124B02_RS10400	COG0515	serine threonine protein kinase
MFUL124B02_RS10400	COG2815	serine threonine protein kinase
MFUL124B02_RS10405	COG2259	Doxx family
MFUL124B02_RS10430	COG0702	epimerase
MFUL124B02_RS10435	COG1733	regulation of RNA biosynthetic process
MFUL124B02_RS10455	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS10460	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS10465	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS10510	COG2234	aminopeptidase activity
MFUL124B02_RS10515	COG0640	Transcriptional regulator
MFUL124B02_RS10525	COG1073	alpha beta
MFUL124B02_RS10540	COG1733	regulation of RNA biosynthetic process
MFUL124B02_RS10570	COG1309	transcriptional regulator
MFUL124B02_RS10575	COG2130	NADP-dependent
MFUL124B02_RS10630	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS10635	COG2814	Major facilitator Superfamily
MFUL124B02_RS10655	COG5507	3-demethylubiquinone-9 3-methyltransferase
MFUL124B02_RS10750	COG3227	Zinc metalloprotease (Elastase)
MFUL124B02_RS10755	COG1595	DNA-templated transcription, initiation
MFUL124B02_RS10780	COG0515	serine threonine protein kinase
MFUL124B02_RS10795	COG0402	S-adenosylhomocysteine deaminase activity
MFUL124B02_RS10805	COG3275	phosphorelay sensor kinase activity
MFUL124B02_RS10840	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS10845	COG1733	regulation of RNA biosynthetic process
MFUL124B02_RS10850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS10860	COG2354	Protein conserved in bacteria
MFUL124B02_RS10945	COG3813	Protein conserved in bacteria
MFUL124B02_RS10950	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS10960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MFUL124B02_RS10975	COG0640	Transcriptional regulator
MFUL124B02_RS11015	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS11025	COG2207	Transcriptional regulator
MFUL124B02_RS11030	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS11045	COG0681	Belongs to the peptidase S26 family
MFUL124B02_RS11055	COG5002	protein histidine kinase activity
MFUL124B02_RS11060	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS11155	COG2124	cytochrome p450
MFUL124B02_RS11195	COG0741	lytic transglycosylase activity
MFUL124B02_RS11195	COG1196	nuclear chromosome segregation
MFUL124B02_RS11195	COG0739	heme binding
MFUL124B02_RS11210	COG2207	Transcriptional regulator
MFUL124B02_RS11215	COG4221	oxidoreductase activity
MFUL124B02_RS11245	COG3338	carbonate dehydratase activity
MFUL124B02_RS11265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MFUL124B02_RS11265	COG2755	lipolytic protein G-D-S-L family
MFUL124B02_RS11275	COG1022	Amp-dependent synthetase and ligase
MFUL124B02_RS11300	COG0657	acetylesterase activity
MFUL124B02_RS11320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MFUL124B02_RS11335	COG0667	Aldo Keto reductase
MFUL124B02_RS11340	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS11350	COG0625	glutathione transferase activity
MFUL124B02_RS11355	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MFUL124B02_RS11465	COG0693	protein deglycase activity
MFUL124B02_RS11485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MFUL124B02_RS11520	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS11605	COG2843	Capsule synthesis protein
MFUL124B02_RS11630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS11635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS11665	COG2204	response regulator
MFUL124B02_RS11680	COG2814	Major facilitator Superfamily
MFUL124B02_RS11685	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS11715	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFUL124B02_RS11755	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFUL124B02_RS11760	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS11805	COG2755	lipolytic protein G-D-S-L family
MFUL124B02_RS11805	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MFUL124B02_RS11840	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS11895	COG1619	proteins homologs of microcin C7 resistance protein MccF
MFUL124B02_RS11905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MFUL124B02_RS11910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MFUL124B02_RS11935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS11970	COG1100	Small GTP-binding protein
MFUL124B02_RS11990	COG0515	serine threonine protein kinase
MFUL124B02_RS11995	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MFUL124B02_RS12000	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MFUL124B02_RS12010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFUL124B02_RS12040	COG0590	tRNA wobble adenosine to inosine editing
MFUL124B02_RS12060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MFUL124B02_RS12090	COG0204	Acyl-transferase
MFUL124B02_RS12095	COG1088	dTDP-glucose 4,6-dehydratase activity
MFUL124B02_RS12115	COG0514	ATP-dependent DNA helicase (RecQ)
MFUL124B02_RS12125	COG2003	Belongs to the UPF0758 family
MFUL124B02_RS12135	COG0492	ferredoxin-NADP+ reductase activity
MFUL124B02_RS12185	COG1832	CoA-binding protein
MFUL124B02_RS12205	COG3284	Transcriptional regulator
MFUL124B02_RS12215	COG2226	methyltransferase
MFUL124B02_RS12220	COG1410	methionine synthase
MFUL124B02_RS12220	COG0646	methionine synthase
MFUL124B02_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS12250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MFUL124B02_RS12255	COG0084	hydrolase, TatD family'
MFUL124B02_RS12285	COG0424	maF-like protein
MFUL124B02_RS12310	COG0210	DNA helicase
MFUL124B02_RS12315	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MFUL124B02_RS12335	COG2137	regulation of response to DNA damage stimulus
MFUL124B02_RS12360	COG0709	Synthesizes selenophosphate from selenide and ATP
MFUL124B02_RS12365	COG0860	N-Acetylmuramoyl-L-alanine amidase
MFUL124B02_RS12370	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MFUL124B02_RS12375	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MFUL124B02_RS12415	COG0544	peptidyl-prolyl cis-trans isomerase activity
MFUL124B02_RS12420	COG0740	serine-type endopeptidase activity
MFUL124B02_RS12430	COG1505	serine-type exopeptidase activity
MFUL124B02_RS12440	COG4166	transmembrane transport
MFUL124B02_RS12460	COG1678	Uncharacterized ACR, COG1678
MFUL124B02_RS12465	COG0271	Belongs to the BolA IbaG family
MFUL124B02_RS12470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MFUL124B02_RS12485	COG0006	proline dipeptidase activity
MFUL124B02_RS12495	COG3148	PFAM DTW domain containing protein
MFUL124B02_RS12520	COG1573	uracil-dna glycosylase
MFUL124B02_RS12525	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS12530	COG0626	cystathionine gamma-synthase activity
MFUL124B02_RS12565	COG2030	dehydratase
MFUL124B02_RS12575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MFUL124B02_RS12600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MFUL124B02_RS12605	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MFUL124B02_RS12615	COG0631	protein serine/threonine phosphatase activity
MFUL124B02_RS12625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MFUL124B02_RS12640	COG0484	heat shock protein binding
MFUL124B02_RS12650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MFUL124B02_RS12655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MFUL124B02_RS12665	COG1428	Deoxynucleoside kinase
MFUL124B02_RS12670	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MFUL124B02_RS12675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MFUL124B02_RS12680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MFUL124B02_RS12700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MFUL124B02_RS12720	COG0779	Required for maturation of 30S ribosomal subunits
MFUL124B02_RS12730	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MFUL124B02_RS12745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MFUL124B02_RS12750	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MFUL124B02_RS12755	COG1185	polyribonucleotide nucleotidyltransferase activity
MFUL124B02_RS12765	COG0739	heme binding
MFUL124B02_RS12770	COG0756	dUTP diphosphatase activity
MFUL124B02_RS12785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MFUL124B02_RS12790	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MFUL124B02_RS12805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS12820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MFUL124B02_RS12835	COG0612	Peptidase, M16
MFUL124B02_RS12860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MFUL124B02_RS12895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MFUL124B02_RS12970	COG0702	epimerase
MFUL124B02_RS12995	COG3604	Transcriptional regulator
MFUL124B02_RS13035	COG3173	Aminoglycoside phosphotransferase
MFUL124B02_RS13050	COG0156	8-amino-7-oxononanoate synthase activity
MFUL124B02_RS13055	COG1136	(ABC) transporter
MFUL124B02_RS13055	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS13090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MFUL124B02_RS13095	COG1116	anion transmembrane transporter activity
MFUL124B02_RS13135	COG5001	Diguanylate cyclase
MFUL124B02_RS13160	COG0544	peptidyl-prolyl cis-trans isomerase activity
MFUL124B02_RS13175	COG3226	Transcriptional regulator
MFUL124B02_RS13205	COG1802	Transcriptional regulator
MFUL124B02_RS13210	COG0179	Fumarylacetoacetate (FAA) hydrolase
MFUL124B02_RS13220	COG0726	polysaccharide deacetylase
MFUL124B02_RS13225	COG5002	protein histidine kinase activity
MFUL124B02_RS13260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MFUL124B02_RS13270	COG0252	asparaginase activity
MFUL124B02_RS13275	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MFUL124B02_RS13285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MFUL124B02_RS13320	COG4585	Histidine kinase
MFUL124B02_RS13355	COG0789	Transcriptional regulator
MFUL124B02_RS13380	COG1733	regulation of RNA biosynthetic process
MFUL124B02_RS13385	COG1733	regulation of RNA biosynthetic process
MFUL124B02_RS13435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MFUL124B02_RS13450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MFUL124B02_RS13460	COG3321	synthase
MFUL124B02_RS13460	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS13460	COG0604	alcohol dehydrogenase
MFUL124B02_RS13470	COG0156	8-amino-7-oxononanoate synthase activity
MFUL124B02_RS13500	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS13500	COG1136	(ABC) transporter
MFUL124B02_RS13515	COG1309	transcriptional regulator
MFUL124B02_RS13525	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS13535	COG1902	pentaerythritol trinitrate reductase activity
MFUL124B02_RS13580	COG0531	amino acid
MFUL124B02_RS13595	COG0784	Response regulator, receiver
MFUL124B02_RS13595	COG2205	protein histidine kinase activity
MFUL124B02_RS13595	COG5002	protein histidine kinase activity
MFUL124B02_RS13600	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MFUL124B02_RS13605	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS13620	COG2124	cytochrome p450
MFUL124B02_RS13680	COG1233	COG1233 Phytoene dehydrogenase and related
MFUL124B02_RS13685	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS13685	COG3321	synthase
MFUL124B02_RS13685	COG0604	alcohol dehydrogenase
MFUL124B02_RS13740	COG0697	spore germination
MFUL124B02_RS13775	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MFUL124B02_RS13860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFUL124B02_RS13880	COG1012	belongs to the aldehyde dehydrogenase family
MFUL124B02_RS13885	COG1278	Cold shock
MFUL124B02_RS13930	COG2326	polyphosphate kinase activity
MFUL124B02_RS13965	COG2205	protein histidine kinase activity
MFUL124B02_RS14035	COG1222	aaa ATPase
MFUL124B02_RS14165	COG1562	ergosterol biosynthetic process
MFUL124B02_RS14215	COG0028	Belongs to the TPP enzyme family
MFUL124B02_RS14220	COG3795	YCII-related domain
MFUL124B02_RS14225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MFUL124B02_RS14230	COG4941	Belongs to the sigma-70 factor family
MFUL124B02_RS14240	COG3507	Belongs to the glycosyl hydrolase 43 family
MFUL124B02_RS14260	COG1012	belongs to the aldehyde dehydrogenase family
MFUL124B02_RS14265	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS14285	COG0328	RNA-DNA hybrid ribonuclease activity
MFUL124B02_RS14320	COG1132	(ABC) transporter
MFUL124B02_RS14325	COG1132	(ABC) transporter
MFUL124B02_RS14340	COG0668	transmembrane transport
MFUL124B02_RS14360	COG0154	amidase activity
MFUL124B02_RS14370	COG1671	Belongs to the UPF0178 family
MFUL124B02_RS14380	COG3275	phosphorelay sensor kinase activity
MFUL124B02_RS14385	COG3279	Response regulator of the LytR AlgR family
MFUL124B02_RS14425	COG0515	serine threonine protein kinase
MFUL124B02_RS14425	COG2815	serine threonine protein kinase
MFUL124B02_RS14445	COG2205	protein histidine kinase activity
MFUL124B02_RS14460	COG0306	phosphate transporter
MFUL124B02_RS14480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFUL124B02_RS14485	COG4257	antibiotic catabolic process
MFUL124B02_RS14520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS14550	COG0427	acetyl-CoA hydrolase
MFUL124B02_RS14560	COG0339	signal peptide processing
MFUL124B02_RS14570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MFUL124B02_RS14615	COG0017	Asparaginyl-tRNA synthetase
MFUL124B02_RS14665	COG0813	purine-nucleoside phosphorylase activity
MFUL124B02_RS14695	COG0513	Belongs to the DEAD box helicase family
MFUL124B02_RS14705	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MFUL124B02_RS14750	COG5002	protein histidine kinase activity
MFUL124B02_RS14750	COG2205	protein histidine kinase activity
MFUL124B02_RS14750	COG0784	Response regulator, receiver
MFUL124B02_RS14760	COG3541	Predicted nucleotidyltransferase
MFUL124B02_RS14785	COG1072	(Pantothenic acid kinase))
MFUL124B02_RS14800	COG2153	protein acetylation
MFUL124B02_RS14810	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS14815	COG2814	Major facilitator Superfamily
MFUL124B02_RS14830	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MFUL124B02_RS14845	COG0175	sulfate reduction
MFUL124B02_RS14850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MFUL124B02_RS14850	COG1648	precorrin-2 dehydrogenase activity
MFUL124B02_RS14970	COG0047	phosphoribosylformylglycinamidine synthase activity
MFUL124B02_RS14970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFUL124B02_RS14975	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFUL124B02_RS14980	COG0517	IMP dehydrogenase activity
MFUL124B02_RS14985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFUL124B02_RS15020	COG0019	diaminopimelate decarboxylase activity
MFUL124B02_RS15025	COG1215	transferase activity, transferring glycosyl groups
MFUL124B02_RS15035	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MFUL124B02_RS15045	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS15050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MFUL124B02_RS15095	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MFUL124B02_RS15100	COG1335	isochorismatase
MFUL124B02_RS15105	COG2197	response regulator
MFUL124B02_RS15135	COG1218	3'(2'),5'-bisphosphate nucleotidase
MFUL124B02_RS15160	COG1228	amidohydrolase
MFUL124B02_RS15170	COG2363	Small membrane protein
MFUL124B02_RS15215	COG2943	transferase activity, transferring hexosyl groups
MFUL124B02_RS15225	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MFUL124B02_RS15245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MFUL124B02_RS15250	COG0386	Belongs to the glutathione peroxidase family
MFUL124B02_RS15290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MFUL124B02_RS15305	COG0515	serine threonine protein kinase
MFUL124B02_RS15325	COG1301	dicarboxylic acid transport
MFUL124B02_RS15345	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS15345	COG1136	(ABC) transporter
MFUL124B02_RS15355	COG0488	(ABC) transporter
MFUL124B02_RS15360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MFUL124B02_RS15390	COG1187	pseudouridine synthase activity
MFUL124B02_RS15400	COG1742	UPF0060 membrane protein
MFUL124B02_RS15425	COG2373	Large extracellular alpha-helical protein
MFUL124B02_RS15430	COG4953	penicillin-binding protein 1C
MFUL124B02_RS15435	COG5337	Spore coat protein CotH
MFUL124B02_RS15470	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS15470	COG1136	(ABC) transporter
MFUL124B02_RS15480	COG1136	(ABC) transporter
MFUL124B02_RS15515	COG1191	sigma factor activity
MFUL124B02_RS15525	COG1766	The M ring may be actively involved in energy transduction
MFUL124B02_RS15580	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MFUL124B02_RS15585	COG2257	FlhB HrpN YscU SpaS Family
MFUL124B02_RS15625	COG4789	Type iii secretion
MFUL124B02_RS15685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MFUL124B02_RS15700	COG0714	Associated with various cellular activities
MFUL124B02_RS15730	COG0616	signal peptide processing
MFUL124B02_RS15745	COG0187	DNA topoisomerase II activity
MFUL124B02_RS15750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFUL124B02_RS15785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MFUL124B02_RS15880	COG1459	type II secretion system
MFUL124B02_RS15910	COG0312	modulator of DNA gyrase
MFUL124B02_RS15915	COG0312	modulator of DNA gyrase
MFUL124B02_RS15925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS15940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MFUL124B02_RS15980	COG5001	Diguanylate cyclase
MFUL124B02_RS15980	COG3300	MHYT domain
MFUL124B02_RS15995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MFUL124B02_RS16000	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MFUL124B02_RS16005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MFUL124B02_RS16040	COG0416	fatty acid biosynthetic process
MFUL124B02_RS16060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFUL124B02_RS16065	COG0667	Aldo Keto reductase
MFUL124B02_RS16075	COG0546	phosphoglycolate phosphatase activity
MFUL124B02_RS16080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MFUL124B02_RS16115	COG0515	serine threonine protein kinase
MFUL124B02_RS16120	COG0564	pseudouridine synthase activity
MFUL124B02_RS16155	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS16160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MFUL124B02_RS16165	COG4589	Belongs to the CDS family
MFUL124B02_RS16170	COG0750	zinc metalloprotease
MFUL124B02_RS16175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MFUL124B02_RS16180	COG1214	PFAM Peptidase M22, glycoprotease
MFUL124B02_RS16185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MFUL124B02_RS16205	COG0314	molybdopterin synthase activity
MFUL124B02_RS16230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MFUL124B02_RS16240	COG0406	alpha-ribazole phosphatase activity
MFUL124B02_RS16250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFUL124B02_RS16265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS16270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MFUL124B02_RS16270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MFUL124B02_RS16290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MFUL124B02_RS16310	COG0515	serine threonine protein kinase
MFUL124B02_RS16320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MFUL124B02_RS16325	COG0316	Belongs to the HesB IscA family
MFUL124B02_RS16330	COG1607	acyl-coa hydrolase
MFUL124B02_RS16340	COG0584	glycerophosphoryl diester phosphodiesterase
MFUL124B02_RS16350	COG0515	serine threonine protein kinase
MFUL124B02_RS16385	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MFUL124B02_RS16405	COG3104	oligopeptide transport
MFUL124B02_RS16435	COG2815	serine threonine protein kinase
MFUL124B02_RS16435	COG0515	serine threonine protein kinase
MFUL124B02_RS16470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MFUL124B02_RS16485	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS16490	COG0456	acetyltransferase
MFUL124B02_RS16500	COG1074	ATP-dependent DNA helicase activity
MFUL124B02_RS16505	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MFUL124B02_RS16550	COG2333	competence protein COMEC
MFUL124B02_RS16550	COG0658	competence protein
MFUL124B02_RS16555	COG1329	Transcriptional regulator
MFUL124B02_RS16570	COG0215	cysteine-tRNA ligase activity
MFUL124B02_RS16580	COG0556	nucleotide-excision repair
MFUL124B02_RS16585	COG0322	excinuclease ABC activity
MFUL124B02_RS16655	COG0424	maF-like protein
MFUL124B02_RS16660	COG3706	GGDEF domain
MFUL124B02_RS16665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MFUL124B02_RS16680	COG0768	penicillin binding
MFUL124B02_RS16685	COG0772	Belongs to the SEDS family
MFUL124B02_RS16700	COG3118	belongs to the thioredoxin family
MFUL124B02_RS16715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MFUL124B02_RS16720	COG0181	hydroxymethylbilane synthase activity
MFUL124B02_RS16725	COG1587	Uroporphyrinogen-III synthase
MFUL124B02_RS16735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MFUL124B02_RS16795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MFUL124B02_RS16800	COG0022	dehydrogenase e1 component
MFUL124B02_RS16805	COG0508	dehydrogenase complex catalyzes the overall conversion of
MFUL124B02_RS16820	COG3852	Histidine kinase
MFUL124B02_RS16830	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS16855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MFUL124B02_RS16895	COG0784	Response regulator, receiver
MFUL124B02_RS16955	COG1100	Small GTP-binding protein
MFUL124B02_RS16960	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MFUL124B02_RS16965	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MFUL124B02_RS16970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MFUL124B02_RS16980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MFUL124B02_RS16985	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS16990	COG0596	Alpha beta hydrolase
MFUL124B02_RS17000	COG1683	Conserved Protein
MFUL124B02_RS17005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MFUL124B02_RS17010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MFUL124B02_RS17015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS17025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MFUL124B02_RS17030	COG0285	dihydrofolate synthase activity
MFUL124B02_RS17050	COG1396	sequence-specific DNA binding
MFUL124B02_RS17060	COG1309	transcriptional regulator
MFUL124B02_RS17065	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS17080	COG3568	Endonuclease Exonuclease Phosphatase
MFUL124B02_RS17130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MFUL124B02_RS17135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MFUL124B02_RS17140	COG1034	ATP synthesis coupled electron transport
MFUL124B02_RS17145	COG0649	NAD binding
MFUL124B02_RS17170	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MFUL124B02_RS17175	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MFUL124B02_RS17190	COG3119	arylsulfatase activity
MFUL124B02_RS17195	COG0613	PHP domain protein
MFUL124B02_RS17200	COG1959	2 iron, 2 sulfur cluster binding
MFUL124B02_RS17220	COG1166	arginine decarboxylase activity
MFUL124B02_RS17235	COG0484	heat shock protein binding
MFUL124B02_RS17240	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS17255	COG2172	sigma factor antagonist activity
MFUL124B02_RS17270	COG1366	Belongs to the anti-sigma-factor antagonist family
MFUL124B02_RS17415	COG3227	Zinc metalloprotease (Elastase)
MFUL124B02_RS17430	COG1796	DNA polymerase
MFUL124B02_RS17430	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MFUL124B02_RS17440	COG0521	Mo-molybdopterin cofactor biosynthetic process
MFUL124B02_RS17465	COG1233	COG1233 Phytoene dehydrogenase and related
MFUL124B02_RS17480	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS17525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MFUL124B02_RS17530	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS17545	COG0110	maltose O-acetyltransferase activity
MFUL124B02_RS17560	COG1136	(ABC) transporter
MFUL124B02_RS17560	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS17570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS17600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MFUL124B02_RS17600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MFUL124B02_RS17610	COG0084	hydrolase, TatD family'
MFUL124B02_RS17620	COG3481	metal-dependent phosphohydrolase, HD sub domain
MFUL124B02_RS17625	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MFUL124B02_RS17635	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
MFUL124B02_RS17645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MFUL124B02_RS17660	COG0126	phosphoglycerate kinase activity
MFUL124B02_RS17665	COG0149	triose-phosphate isomerase activity
MFUL124B02_RS17680	COG0582	viral genome integration into host DNA
MFUL124B02_RS17715	COG4584	PFAM Integrase catalytic
MFUL124B02_RS17720	COG1484	DNA-dependent DNA replication
MFUL124B02_RS17725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MFUL124B02_RS17765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MFUL124B02_RS17790	COG2204	response regulator
MFUL124B02_RS17835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MFUL124B02_RS17840	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS17850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MFUL124B02_RS17880	COG2986	histidine ammonia-lyase
MFUL124B02_RS17905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFUL124B02_RS17910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFUL124B02_RS17930	COG0515	serine threonine protein kinase
MFUL124B02_RS17930	COG2815	serine threonine protein kinase
MFUL124B02_RS17945	COG0346	lactoylglutathione lyase activity
MFUL124B02_RS17950	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS17960	COG1012	belongs to the aldehyde dehydrogenase family
MFUL124B02_RS17980	COG0668	transmembrane transport
MFUL124B02_RS18015	COG1454	alcohol dehydrogenase
MFUL124B02_RS18020	COG0824	Thioesterase
MFUL124B02_RS18055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MFUL124B02_RS18085	COG2226	methyltransferase
MFUL124B02_RS18090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MFUL124B02_RS18120	COG1070	Carbohydrate kinase
MFUL124B02_RS18130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MFUL124B02_RS18135	COG0412	Dienelactone hydrolase
MFUL124B02_RS18190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MFUL124B02_RS18210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFUL124B02_RS18215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MFUL124B02_RS18250	COG0714	Associated with various cellular activities
MFUL124B02_RS18265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFUL124B02_RS18310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MFUL124B02_RS18320	COG2366	antibiotic biosynthetic process
MFUL124B02_RS18325	COG1183	phosphatidylcholine synthase activity
MFUL124B02_RS18340	COG0515	serine threonine protein kinase
MFUL124B02_RS18350	COG0515	serine threonine protein kinase
MFUL124B02_RS18360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFUL124B02_RS18365	COG0138	bifunctional purine biosynthesis protein purh
MFUL124B02_RS18375	COG0151	Belongs to the GarS family
MFUL124B02_RS18380	COG0795	lipopolysaccharide-transporting ATPase activity
MFUL124B02_RS18395	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS18400	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS18405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MFUL124B02_RS18435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFUL124B02_RS18440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFUL124B02_RS18445	COG3411	Ferredoxin
MFUL124B02_RS18455	COG0670	Belongs to the BI1 family
MFUL124B02_RS18505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MFUL124B02_RS18510	COG1121	(ABC) transporter
MFUL124B02_RS18525	COG3746	phosphate-selective porin O and P
MFUL124B02_RS18540	COG0302	gtp cyclohydrolase
MFUL124B02_RS18545	COG0277	FAD linked oxidase domain protein
MFUL124B02_RS18565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MFUL124B02_RS18575	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS18585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MFUL124B02_RS18605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFUL124B02_RS18610	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS18630	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MFUL124B02_RS18650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFUL124B02_RS18655	COG1692	metallophosphoesterase
MFUL124B02_RS18670	COG0515	serine threonine protein kinase
MFUL124B02_RS18720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MFUL124B02_RS18730	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS18730	COG1196	nuclear chromosome segregation
MFUL124B02_RS18730	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS18730	COG1196	nuclear chromosome segregation
MFUL124B02_RS18745	COG1543	Belongs to the glycosyl hydrolase 57 family
MFUL124B02_RS18750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS18765	COG1496	oxidoreductase activity
MFUL124B02_RS18785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFUL124B02_RS18810	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MFUL124B02_RS18835	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MFUL124B02_RS18840	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MFUL124B02_RS18850	COG0484	heat shock protein binding
MFUL124B02_RS18855	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS18890	COG0237	dephospho-CoA kinase activity
MFUL124B02_RS18905	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MFUL124B02_RS18930	COG0167	dihydroorotate dehydrogenase activity
MFUL124B02_RS18935	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MFUL124B02_RS18940	COG2840	Smr protein MutS2
MFUL124B02_RS18945	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MFUL124B02_RS18950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MFUL124B02_RS18980	COG1397	ADP-ribosylglycohydrolase
MFUL124B02_RS18985	COG3852	Histidine kinase
MFUL124B02_RS19005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MFUL124B02_RS19010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MFUL124B02_RS19015	COG0509	glycine decarboxylation via glycine cleavage system
MFUL124B02_RS19020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MFUL124B02_RS19020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MFUL124B02_RS19050	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS19065	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MFUL124B02_RS19090	COG1643	Atp-dependent helicase
MFUL124B02_RS19130	COG0189	ligase activity
MFUL124B02_RS19140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFUL124B02_RS19170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MFUL124B02_RS19190	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MFUL124B02_RS19195	COG0081	regulation of translation
MFUL124B02_RS19200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MFUL124B02_RS19205	COG0222	ribosome binding
MFUL124B02_RS19210	COG0085	RNA polymerase activity
MFUL124B02_RS19215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFUL124B02_RS19230	COG0741	lytic transglycosylase activity
MFUL124B02_RS19230	COG1196	nuclear chromosome segregation
MFUL124B02_RS19230	COG0739	heme binding
MFUL124B02_RS19255	COG1381	Involved in DNA repair and RecF pathway recombination
MFUL124B02_RS19300	COG2204	response regulator
MFUL124B02_RS19325	COG5002	protein histidine kinase activity
MFUL124B02_RS19330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MFUL124B02_RS19335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFUL124B02_RS19345	COG1309	transcriptional regulator
MFUL124B02_RS19355	COG2207	Transcriptional regulator
MFUL124B02_RS19370	COG0515	serine threonine protein kinase
MFUL124B02_RS19375	COG0752	glycyl-tRNA synthetase alpha subunit
MFUL124B02_RS19405	COG1450	Type ii and iii secretion system protein
MFUL124B02_RS19420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFUL124B02_RS19420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFUL124B02_RS19435	COG1872	DUF167
MFUL124B02_RS19535	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFUL124B02_RS19555	COG1505	serine-type exopeptidase activity
MFUL124B02_RS19560	COG2027	D-alanyl-D-alanine carboxypeptidase
MFUL124B02_RS19600	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MFUL124B02_RS19655	COG1268	BioY protein
MFUL124B02_RS19690	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MFUL124B02_RS19700	COG0564	pseudouridine synthase activity
MFUL124B02_RS19845	COG3608	succinylglutamate desuccinylase aspartoacylase
MFUL124B02_RS19845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MFUL124B02_RS19850	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS19855	COG2814	Major facilitator Superfamily
MFUL124B02_RS19860	COG2311	Membrane
MFUL124B02_RS19865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MFUL124B02_RS19870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS19970	COG3590	peptidase
MFUL124B02_RS19980	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MFUL124B02_RS19980	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MFUL124B02_RS19995	COG3034	peptidoglycan biosynthetic process
MFUL124B02_RS20030	COG0531	amino acid
MFUL124B02_RS20085	COG2080	2 iron, 2 sulfur cluster binding
MFUL124B02_RS20105	COG0840	transmembrane signaling receptor activity
MFUL124B02_RS20120	COG0531	amino acid
MFUL124B02_RS20145	COG4935	Belongs to the peptidase S8 family
MFUL124B02_RS20145	COG1404	Belongs to the peptidase S8 family
MFUL124B02_RS20195	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MFUL124B02_RS20215	COG1408	metallophosphoesterase
MFUL124B02_RS20220	COG4221	oxidoreductase activity
MFUL124B02_RS20225	COG1136	(ABC) transporter
MFUL124B02_RS20225	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS20235	COG1136	(ABC) transporter
MFUL124B02_RS20245	COG4191	Histidine kinase
MFUL124B02_RS20250	COG2204	response regulator
MFUL124B02_RS20270	COG0823	Involved in the tonB-independent uptake of proteins
MFUL124B02_RS20285	COG1193	negative regulation of DNA recombination
MFUL124B02_RS20300	COG3876	Protein conserved in bacteria
MFUL124B02_RS20310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MFUL124B02_RS20335	COG0542	response to heat
MFUL124B02_RS20350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFUL124B02_RS20355	COG1136	(ABC) transporter
MFUL124B02_RS20360	COG1136	(ABC) transporter
MFUL124B02_RS20360	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS20395	COG2205	protein histidine kinase activity
MFUL124B02_RS20400	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS20430	COG2304	oxidoreductase activity
MFUL124B02_RS20440	COG5599	Phosphatase
MFUL124B02_RS20455	COG3220	belongs to the UPF0276 family
MFUL124B02_RS20495	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MFUL124B02_RS20495	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MFUL124B02_RS20500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MFUL124B02_RS20520	COG1595	DNA-templated transcription, initiation
MFUL124B02_RS20525	COG0686	Belongs to the AlaDH PNT family
MFUL124B02_RS20535	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS20590	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MFUL124B02_RS20610	COG1131	(ABC) transporter
MFUL124B02_RS20620	COG0113	porphobilinogen synthase activity
MFUL124B02_RS20635	COG1181	Belongs to the D-alanine--D-alanine ligase family
MFUL124B02_RS20655	COG0628	permease
MFUL124B02_RS20695	COG1408	metallophosphoesterase
MFUL124B02_RS20710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MFUL124B02_RS20715	COG0513	Belongs to the DEAD box helicase family
MFUL124B02_RS20740	COG1703	isobutyryl-CoA mutase activity
MFUL124B02_RS20740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MFUL124B02_RS20740	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MFUL124B02_RS20770	COG0515	serine threonine protein kinase
MFUL124B02_RS20800	COG1131	(ABC) transporter
MFUL124B02_RS20815	COG4585	Histidine kinase
MFUL124B02_RS20825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MFUL124B02_RS20835	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MFUL124B02_RS20850	COG0529	Catalyzes the synthesis of activated sulfate
MFUL124B02_RS20850	COG2046	Belongs to the sulfate adenylyltransferase family
MFUL124B02_RS20855	COG1606	tRNA processing
MFUL124B02_RS20865	COG0101	tRNA pseudouridine synthase activity
MFUL124B02_RS20905	COG0515	serine threonine protein kinase
MFUL124B02_RS20910	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS20950	COG0825	malonyl-CoA metabolic process
MFUL124B02_RS20955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MFUL124B02_RS20960	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MFUL124B02_RS20965	COG0741	lytic transglycosylase activity
MFUL124B02_RS20980	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MFUL124B02_RS21005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MFUL124B02_RS21045	COG2815	serine threonine protein kinase
MFUL124B02_RS21045	COG0515	serine threonine protein kinase
MFUL124B02_RS21070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS21095	COG0667	Aldo Keto reductase
MFUL124B02_RS21130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MFUL124B02_RS21145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MFUL124B02_RS21180	COG0488	(ABC) transporter
MFUL124B02_RS21280	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS21295	COG2909	trisaccharide binding
MFUL124B02_RS21405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MFUL124B02_RS21425	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS21450	COG3320	Male sterility
MFUL124B02_RS21450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFUL124B02_RS21460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MFUL124B02_RS21525	COG0708	Exodeoxyribonuclease III
MFUL124B02_RS21560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MFUL124B02_RS21565	COG0493	'glutamate synthase
MFUL124B02_RS21585	COG0585	pseudouridine synthase activity
MFUL124B02_RS21630	COG1192	Involved in chromosome partitioning
MFUL124B02_RS21635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MFUL124B02_RS21660	COG0069	glutamate synthase activity
MFUL124B02_RS21660	COG0070	glutamate synthase
MFUL124B02_RS21660	COG0067	glutamate synthase
MFUL124B02_RS21680	COG4774	siderophore transport
MFUL124B02_RS21685	COG3128	pkhd-type hydroxylase
MFUL124B02_RS21715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MFUL124B02_RS21725	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MFUL124B02_RS21785	COG0386	Belongs to the glutathione peroxidase family
MFUL124B02_RS21790	COG2133	pyrroloquinoline quinone binding
MFUL124B02_RS21795	COG1228	amidohydrolase
MFUL124B02_RS21800	COG0456	acetyltransferase
MFUL124B02_RS21810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MFUL124B02_RS21815	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MFUL124B02_RS21840	COG0860	N-Acetylmuramoyl-L-alanine amidase
MFUL124B02_RS21855	COG2207	Transcriptional regulator
MFUL124B02_RS21885	COG2234	aminopeptidase activity
MFUL124B02_RS21890	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MFUL124B02_RS21895	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MFUL124B02_RS21900	COG2124	cytochrome p450
MFUL124B02_RS21905	COG2814	Major facilitator Superfamily
MFUL124B02_RS21940	COG3279	Response regulator of the LytR AlgR family
MFUL124B02_RS21950	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS21955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MFUL124B02_RS21960	COG4770	biotin carboxylase activity
MFUL124B02_RS21980	COG0437	4 iron, 4 sulfur cluster binding
MFUL124B02_RS21990	COG3383	formate dehydrogenase (NAD+) activity
MFUL124B02_RS21990	COG0243	molybdopterin cofactor binding
MFUL124B02_RS21995	COG2124	cytochrome p450
MFUL124B02_RS22005	COG0135	phosphoribosylanthranilate isomerase activity
MFUL124B02_RS22025	COG0398	Pfam SNARE associated Golgi protein
MFUL124B02_RS22045	COG0475	glutathione-regulated potassium exporter activity
MFUL124B02_RS22045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MFUL124B02_RS22050	COG0009	L-threonylcarbamoyladenylate synthase
MFUL124B02_RS22060	COG4974	Belongs to the 'phage' integrase family
MFUL124B02_RS22080	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MFUL124B02_RS22085	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MFUL124B02_RS22100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS22115	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MFUL124B02_RS22120	COG1111	helicase
MFUL124B02_RS22120	COG1205	dead DEAH box helicase
MFUL124B02_RS22125	COG3359	exonuclease
MFUL124B02_RS22130	COG1047	Peptidyl-prolyl cis-trans
MFUL124B02_RS22150	COG1946	Acyl-CoA thioesterase
MFUL124B02_RS22175	COG0456	acetyltransferase
MFUL124B02_RS22175	COG1846	Transcriptional regulator
MFUL124B02_RS22220	COG0842	Transport permease protein
MFUL124B02_RS22225	COG0842	Transport permease protein
MFUL124B02_RS22225	COG1129	ABC transporter
MFUL124B02_RS22230	COG1131	(ABC) transporter
MFUL124B02_RS22235	COG1131	(ABC) transporter
MFUL124B02_RS22265	COG3852	Histidine kinase
MFUL124B02_RS22280	COG0430	RNA-3'-phosphate cyclase activity
MFUL124B02_RS22310	COG0489	protein tyrosine kinase activity
MFUL124B02_RS22325	COG1250	3-hydroxyacyl-CoA dehydrogenase
MFUL124B02_RS22330	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS22340	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS22350	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS22370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MFUL124B02_RS22375	COG1309	transcriptional regulator
MFUL124B02_RS22380	COG0183	Belongs to the thiolase family
MFUL124B02_RS22385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MFUL124B02_RS22390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MFUL124B02_RS22400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFUL124B02_RS22410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MFUL124B02_RS22430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MFUL124B02_RS22435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MFUL124B02_RS22450	COG0586	Pfam SNARE associated Golgi protein
MFUL124B02_RS22455	COG0534	Mate efflux family protein
MFUL124B02_RS22465	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS22470	COG0516	GMP reductase activity
MFUL124B02_RS22470	COG0517	IMP dehydrogenase activity
MFUL124B02_RS22480	COG0519	Catalyzes the synthesis of GMP from XMP
MFUL124B02_RS22480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MFUL124B02_RS22485	COG4990	cell redox homeostasis
MFUL124B02_RS22485	COG3591	Belongs to the peptidase S1B family
MFUL124B02_RS22490	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS22490	COG1136	(ABC) transporter
MFUL124B02_RS22510	COG0494	nUDIX hydrolase
MFUL124B02_RS22525	COG1160	GTP binding
MFUL124B02_RS22530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MFUL124B02_RS22540	COG0571	ribonuclease III activity
MFUL124B02_RS22550	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS22560	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS22570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MFUL124B02_RS22595	COG0156	8-amino-7-oxononanoate synthase activity
MFUL124B02_RS22600	COG0456	acetyltransferase
MFUL124B02_RS22630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MFUL124B02_RS22630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MFUL124B02_RS22655	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS22665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MFUL124B02_RS22695	COG0124	histidyl-tRNA synthetase
MFUL124B02_RS22700	COG0688	phosphatidylethanolamine metabolic process
MFUL124B02_RS22725	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MFUL124B02_RS22735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MFUL124B02_RS22755	COG0564	pseudouridine synthase activity
MFUL124B02_RS22760	COG0612	Peptidase, M16
MFUL124B02_RS22765	COG0612	Peptidase, M16
MFUL124B02_RS22770	COG2197	response regulator
MFUL124B02_RS22790	COG2136	Putative SAM-dependent methyltransferase
MFUL124B02_RS22790	COG2521	methyltransferase
MFUL124B02_RS22800	COG3706	GGDEF domain
MFUL124B02_RS22860	COG0515	serine threonine protein kinase
MFUL124B02_RS22870	COG0515	serine threonine protein kinase
MFUL124B02_RS22875	COG0515	serine threonine protein kinase
MFUL124B02_RS22880	COG0515	serine threonine protein kinase
MFUL124B02_RS22920	COG5002	protein histidine kinase activity
MFUL124B02_RS22925	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS22935	COG0366	Alpha amylase catalytic
MFUL124B02_RS22950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MFUL124B02_RS22955	COG2249	NAD(P)H dehydrogenase (quinone) activity
MFUL124B02_RS23015	COG0840	transmembrane signaling receptor activity
MFUL124B02_RS23080	COG2076	Multidrug Resistance protein
MFUL124B02_RS23095	COG2985	domain, Protein
MFUL124B02_RS23125	COG0252	asparaginase activity
MFUL124B02_RS23135	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MFUL124B02_RS23140	COG2423	ornithine cyclodeaminase activity
MFUL124B02_RS23155	COG2301	Belongs to the HpcH HpaI aldolase family
MFUL124B02_RS23160	COG0156	8-amino-7-oxononanoate synthase activity
MFUL124B02_RS23170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS23175	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS23180	COG1169	isochorismate synthase
MFUL124B02_RS23185	COG1021	2,3-dihydroxybenzoate-AMP ligase
MFUL124B02_RS23190	COG1535	isochorismatase
MFUL124B02_RS23190	COG3433	isochorismatase activity
MFUL124B02_RS23195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MFUL124B02_RS23200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFUL124B02_RS23200	COG3320	Male sterility
MFUL124B02_RS23205	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MFUL124B02_RS23210	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MFUL124B02_RS23225	COG0811	peptide transport
MFUL124B02_RS23260	COG0142	geranyltranstransferase activity
MFUL124B02_RS23265	COG2264	protein methyltransferase activity
MFUL124B02_RS23280	COG2175	clavaminate synthase activity
MFUL124B02_RS23300	COG2366	antibiotic biosynthetic process
MFUL124B02_RS23325	COG0776	regulation of translation
MFUL124B02_RS23330	COG0072	phenylalanine-tRNA ligase activity
MFUL124B02_RS23335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MFUL124B02_RS23340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MFUL124B02_RS23345	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MFUL124B02_RS23350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFUL124B02_RS23365	COG0628	permease
MFUL124B02_RS23400	COG1278	Cold shock
MFUL124B02_RS23510	COG3501	Rhs element vgr protein
MFUL124B02_RS23575	COG0477	Major facilitator Superfamily
MFUL124B02_RS23595	COG2304	oxidoreductase activity
MFUL124B02_RS23605	COG4305	rare lipoprotein A
MFUL124B02_RS23610	COG2255	four-way junction helicase activity
MFUL124B02_RS23650	COG0154	amidase activity
MFUL124B02_RS23685	COG0728	peptidoglycan biosynthetic process
MFUL124B02_RS23700	COG2204	response regulator
MFUL124B02_RS23715	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MFUL124B02_RS23720	COG0792	nuclease activity
MFUL124B02_RS23730	COG0335	large ribosomal subunit rRNA binding
MFUL124B02_RS23735	COG0336	Belongs to the RNA methyltransferase TrmD family
MFUL124B02_RS23740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MFUL124B02_RS23745	COG1837	Belongs to the UPF0109 family
MFUL124B02_RS23750	COG0228	four-way junction DNA binding
MFUL124B02_RS23755	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MFUL124B02_RS23765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MFUL124B02_RS23770	COG0045	succinate-CoA ligase (ADP-forming) activity
MFUL124B02_RS23775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MFUL124B02_RS23780	COG1053	succinate dehydrogenase
MFUL124B02_RS23790	COG0538	isocitrate dehydrogenase activity
MFUL124B02_RS23830	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS23835	COG4948	Mandelate Racemase Muconate Lactonizing
MFUL124B02_RS23840	COG1575	Belongs to the MenA family. Type 1 subfamily
MFUL124B02_RS23850	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MFUL124B02_RS23860	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MFUL124B02_RS23865	COG2226	methyltransferase
MFUL124B02_RS23880	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MFUL124B02_RS23885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MFUL124B02_RS23890	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MFUL124B02_RS23895	COG0372	Belongs to the citrate synthase family
MFUL124B02_RS23900	COG1022	Amp-dependent synthetase and ligase
MFUL124B02_RS23925	COG0505	Belongs to the CarA family
MFUL124B02_RS23935	COG0540	Belongs to the ATCase OTCase family
MFUL124B02_RS23940	COG0681	Belongs to the peptidase S26 family
MFUL124B02_RS23945	COG0681	Belongs to the peptidase S26 family
MFUL124B02_RS23950	COG0481	GTPase activity
MFUL124B02_RS23960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MFUL124B02_RS23985	COG0776	regulation of translation
MFUL124B02_RS23995	COG0482	sulfurtransferase activity
MFUL124B02_RS24000	COG0617	tRNA 3'-terminal CCA addition
MFUL124B02_RS24045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MFUL124B02_RS24120	COG0604	alcohol dehydrogenase
MFUL124B02_RS24120	COG3321	synthase
MFUL124B02_RS24130	COG1032	radical SAM domain protein
MFUL124B02_RS24145	COG0003	Pfam Anion-transporting ATPase
MFUL124B02_RS24185	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS24190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MFUL124B02_RS24195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MFUL124B02_RS24200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MFUL124B02_RS24205	COG0529	Catalyzes the synthesis of activated sulfate
MFUL124B02_RS24235	COG1215	transferase activity, transferring glycosyl groups
MFUL124B02_RS24340	COG2146	nitrite reductase [NAD(P)H] activity
MFUL124B02_RS24340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MFUL124B02_RS24370	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS24390	COG1215	transferase activity, transferring glycosyl groups
MFUL124B02_RS24405	COG0527	aspartate kinase activity
MFUL124B02_RS24410	COG2986	histidine ammonia-lyase
MFUL124B02_RS24420	COG3961	Belongs to the TPP enzyme family
MFUL124B02_RS24425	COG1741	Belongs to the pirin family
MFUL124B02_RS24460	COG1058	Belongs to the CinA family
MFUL124B02_RS24460	COG1546	Belongs to the CinA family
MFUL124B02_RS24470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MFUL124B02_RS24480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MFUL124B02_RS24480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MFUL124B02_RS24485	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MFUL124B02_RS24495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MFUL124B02_RS24510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MFUL124B02_RS24530	COG3695	enzyme binding
MFUL124B02_RS24545	COG3220	belongs to the UPF0276 family
MFUL124B02_RS24570	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MFUL124B02_RS24590	COG0242	peptide deformylase activity
MFUL124B02_RS24615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MFUL124B02_RS24625	COG0436	Aminotransferase
MFUL124B02_RS24630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MFUL124B02_RS24635	COG0742	ribosomal rna small subunit methyltransferase
MFUL124B02_RS24645	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS24655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MFUL124B02_RS24695	COG2124	cytochrome p450
MFUL124B02_RS24740	COG2124	cytochrome p450
MFUL124B02_RS24770	COG1695	Transcriptional regulator
MFUL124B02_RS24845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MFUL124B02_RS24910	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MFUL124B02_RS24935	COG1196	nuclear chromosome segregation
MFUL124B02_RS24935	COG0741	lytic transglycosylase activity
MFUL124B02_RS24935	COG0739	heme binding
MFUL124B02_RS24945	COG0714	Associated with various cellular activities
MFUL124B02_RS24960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFUL124B02_RS24965	COG1297	OPT oligopeptide transporter protein
MFUL124B02_RS24995	COG0564	pseudouridine synthase activity
MFUL124B02_RS25020	COG1921	L-seryl-tRNASec selenium transferase activity
MFUL124B02_RS25025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MFUL124B02_RS25085	COG0741	lytic transglycosylase activity
MFUL124B02_RS25090	COG4191	Histidine kinase
MFUL124B02_RS25095	COG0488	(ABC) transporter
MFUL124B02_RS25110	COG1956	GAF domain-containing protein
MFUL124B02_RS25115	COG2313	pseudouridylate synthase activity
MFUL124B02_RS25155	COG0203	ribosomal protein L17
MFUL124B02_RS25160	COG0202	RNA polymerase activity
MFUL124B02_RS25165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MFUL124B02_RS25170	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MFUL124B02_RS25175	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MFUL124B02_RS25180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MFUL124B02_RS25190	COG0563	adenylate kinase activity
MFUL124B02_RS25195	COG0201	protein transport
MFUL124B02_RS25200	COG0200	Binds to the 23S rRNA
MFUL124B02_RS25205	COG1841	ribosomal large subunit assembly
MFUL124B02_RS25210	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MFUL124B02_RS25215	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MFUL124B02_RS25220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MFUL124B02_RS25225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MFUL124B02_RS25230	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFUL124B02_RS25240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MFUL124B02_RS25245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MFUL124B02_RS25250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MFUL124B02_RS25255	COG0255	Belongs to the universal ribosomal protein uL29 family
MFUL124B02_RS25260	COG0255	Belongs to the universal ribosomal protein uL29 family
MFUL124B02_RS25265	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MFUL124B02_RS25270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MFUL124B02_RS25275	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MFUL124B02_RS25280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MFUL124B02_RS25285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MFUL124B02_RS25290	COG0089	rRNA binding
MFUL124B02_RS25295	COG0088	Forms part of the polypeptide exit tunnel
MFUL124B02_RS25300	COG0051	transcription antitermination factor activity, RNA binding
MFUL124B02_RS25310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MFUL124B02_RS25315	COG0049	tRNA binding
MFUL124B02_RS25320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MFUL124B02_RS25325	COG0454	-acetyltransferase
MFUL124B02_RS25345	COG5002	protein histidine kinase activity
MFUL124B02_RS25350	COG0018	arginyl-trna synthetase
MFUL124B02_RS25355	COG2937	Belongs to the GPAT DAPAT family
MFUL124B02_RS25390	COG1404	Belongs to the peptidase S8 family
MFUL124B02_RS25430	COG0598	Magnesium transport protein CorA
MFUL124B02_RS25435	COG2267	carboxylic ester hydrolase activity
MFUL124B02_RS25490	COG2022	thiamine diphosphate biosynthetic process
MFUL124B02_RS25495	COG0352	thiamine-phosphate diphosphorylase activity
MFUL124B02_RS25540	COG4133	protoheme IX ABC transporter activity
MFUL124B02_RS25550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MFUL124B02_RS25560	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MFUL124B02_RS25565	COG1138	Cytochrome C-type biogenesis protein
MFUL124B02_RS25585	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MFUL124B02_RS25595	COG3088	subunit of a heme lyase
MFUL124B02_RS25625	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MFUL124B02_RS25630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MFUL124B02_RS25635	COG0489	protein tyrosine kinase activity
MFUL124B02_RS25660	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS25670	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MFUL124B02_RS25700	COG1595	DNA-templated transcription, initiation
MFUL124B02_RS25710	COG0077	Prephenate dehydratase
MFUL124B02_RS25710	COG1605	Chorismate mutase
MFUL124B02_RS25715	COG1605	Chorismate mutase
MFUL124B02_RS25715	COG0077	Prephenate dehydratase
MFUL124B02_RS25720	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MFUL124B02_RS25740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MFUL124B02_RS25745	COG2204	response regulator
MFUL124B02_RS25765	COG0768	penicillin binding
MFUL124B02_RS25775	COG1131	(ABC) transporter
MFUL124B02_RS25785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MFUL124B02_RS25785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MFUL124B02_RS25815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MFUL124B02_RS25850	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS25870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MFUL124B02_RS25880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MFUL124B02_RS25905	COG1111	helicase
MFUL124B02_RS25905	COG1205	dead DEAH box helicase
MFUL124B02_RS25910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MFUL124B02_RS26045	COG0515	serine threonine protein kinase
MFUL124B02_RS26060	COG0557	exoribonuclease II activity
MFUL124B02_RS26070	COG0303	'Molybdopterin
MFUL124B02_RS26080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MFUL124B02_RS26080	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MFUL124B02_RS26110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MFUL124B02_RS26115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MFUL124B02_RS26130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MFUL124B02_RS26130	COG0140	phosphoribosyl-ATP diphosphatase activity
MFUL124B02_RS26140	COG0107	imidazoleglycerol-phosphate synthase activity
MFUL124B02_RS26145	COG0131	Imidazoleglycerol-phosphate dehydratase
MFUL124B02_RS26150	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MFUL124B02_RS26155	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MFUL124B02_RS26160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MFUL124B02_RS26165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MFUL124B02_RS26170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MFUL124B02_RS26175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MFUL124B02_RS26175	COG2022	thiamine diphosphate biosynthetic process
MFUL124B02_RS26195	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MFUL124B02_RS26200	COG0516	GMP reductase activity
MFUL124B02_RS26200	COG0517	IMP dehydrogenase activity
MFUL124B02_RS26205	COG0471	metal ion transport
MFUL124B02_RS26215	COG2204	response regulator
MFUL124B02_RS26225	COG0501	Belongs to the peptidase M48B family
MFUL124B02_RS26230	COG4191	Histidine kinase
MFUL124B02_RS26235	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS26235	COG4566	intracellular signal transduction
MFUL124B02_RS26240	COG2205	protein histidine kinase activity
MFUL124B02_RS26265	COG3852	Histidine kinase
MFUL124B02_RS26340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFUL124B02_RS26350	COG1309	transcriptional regulator
MFUL124B02_RS26355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MFUL124B02_RS26370	COG3425	synthase
MFUL124B02_RS26380	COG0667	Aldo Keto reductase
MFUL124B02_RS26395	COG0625	glutathione transferase activity
MFUL124B02_RS26400	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS26405	COG0673	inositol 2-dehydrogenase activity
MFUL124B02_RS26600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MFUL124B02_RS26620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MFUL124B02_RS26640	COG0494	nUDIX hydrolase
MFUL124B02_RS26660	COG2204	response regulator
MFUL124B02_RS26665	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MFUL124B02_RS26685	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MFUL124B02_RS26695	COG1228	amidohydrolase
MFUL124B02_RS26700	COG0121	glutamine amidotransferase
MFUL124B02_RS26710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MFUL124B02_RS26710	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MFUL124B02_RS26715	COG0736	holo-[acyl-carrier-protein] synthase activity
MFUL124B02_RS26720	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MFUL124B02_RS26725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MFUL124B02_RS26730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MFUL124B02_RS26735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFUL124B02_RS26740	COG0037	tRNA processing
MFUL124B02_RS26785	COG2226	methyltransferase
MFUL124B02_RS26795	COG3246	L-lysine catabolic process to acetate
MFUL124B02_RS26800	COG1607	acyl-coa hydrolase
MFUL124B02_RS26805	COG5012	cobalamin binding
MFUL124B02_RS26815	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MFUL124B02_RS26820	COG0753	catalase activity
MFUL124B02_RS26830	COG0604	alcohol dehydrogenase
MFUL124B02_RS26840	COG1573	uracil-dna glycosylase
MFUL124B02_RS26850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MFUL124B02_RS26865	COG0631	protein serine/threonine phosphatase activity
MFUL124B02_RS26895	COG4191	Histidine kinase
MFUL124B02_RS26925	COG4104	PAAR repeat-containing protein
MFUL124B02_RS26925	COG3209	COG3209 Rhs family protein
MFUL124B02_RS26955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MFUL124B02_RS26960	COG1404	Belongs to the peptidase S8 family
MFUL124B02_RS26970	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MFUL124B02_RS26985	COG1132	(ABC) transporter
MFUL124B02_RS26990	COG1132	(ABC) transporter
MFUL124B02_RS27015	COG2274	protein secretion by the type I secretion system
MFUL124B02_RS27055	COG4464	protein tyrosine phosphatase activity
MFUL124B02_RS27060	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MFUL124B02_RS27065	COG3321	synthase
MFUL124B02_RS27065	COG0604	alcohol dehydrogenase
MFUL124B02_RS27075	COG0515	serine threonine protein kinase
MFUL124B02_RS27075	COG2815	serine threonine protein kinase
MFUL124B02_RS27100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS27110	COG5002	protein histidine kinase activity
MFUL124B02_RS27110	COG2198	Histidine kinase
MFUL124B02_RS27110	COG0784	Response regulator, receiver
MFUL124B02_RS27125	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS27160	COG5002	protein histidine kinase activity
MFUL124B02_RS27165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MFUL124B02_RS27185	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MFUL124B02_RS27200	COG1494	fructose-1,6-bisphosphatase
MFUL124B02_RS27205	COG0824	Thioesterase
MFUL124B02_RS27210	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
MFUL124B02_RS27220	COG0596	Alpha beta hydrolase
MFUL124B02_RS27230	COG0157	Belongs to the NadC ModD family
MFUL124B02_RS27235	COG0525	valine-tRNA ligase activity
MFUL124B02_RS27250	COG3706	GGDEF domain
MFUL124B02_RS27260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MFUL124B02_RS27260	COG2205	protein histidine kinase activity
MFUL124B02_RS27270	COG0459	protein refolding
MFUL124B02_RS27410	COG2226	methyltransferase
MFUL124B02_RS27425	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MFUL124B02_RS27455	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS27475	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS27480	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS27485	COG0183	Belongs to the thiolase family
MFUL124B02_RS27495	COG1012	belongs to the aldehyde dehydrogenase family
MFUL124B02_RS27500	COG2010	Cytochrome c
MFUL124B02_RS27505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MFUL124B02_RS27525	COG2423	ornithine cyclodeaminase activity
MFUL124B02_RS27535	COG0148	phosphopyruvate hydratase activity
MFUL124B02_RS27550	COG4942	peptidase
MFUL124B02_RS27615	COG3135	benzoate transporter
MFUL124B02_RS27630	COG2022	thiamine diphosphate biosynthetic process
MFUL124B02_RS27630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MFUL124B02_RS27660	COG0515	serine threonine protein kinase
MFUL124B02_RS27670	COG4771	TonB-dependent receptor
MFUL124B02_RS27685	COG2208	phosphoserine phosphatase activity
MFUL124B02_RS27685	COG2770	Histidine kinase
MFUL124B02_RS27695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MFUL124B02_RS27700	COG0022	dehydrogenase e1 component
MFUL124B02_RS27730	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MFUL124B02_RS27730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MFUL124B02_RS27735	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MFUL124B02_RS27745	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS27750	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS27830	COG2205	protein histidine kinase activity
MFUL124B02_RS27830	COG4191	Histidine kinase
MFUL124B02_RS27830	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS27895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MFUL124B02_RS27895	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MFUL124B02_RS27900	COG0343	queuine tRNA-ribosyltransferase activity
MFUL124B02_RS27905	COG0488	(ABC) transporter
MFUL124B02_RS27920	COG1959	2 iron, 2 sulfur cluster binding
MFUL124B02_RS27925	COG1295	ribonuclease BN
MFUL124B02_RS27930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFUL124B02_RS27995	COG1216	Glycosyl transferase, family 2
MFUL124B02_RS28000	COG1216	Glycosyl transferase, family 2
MFUL124B02_RS28045	COG0741	lytic transglycosylase activity
MFUL124B02_RS28070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MFUL124B02_RS28115	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MFUL124B02_RS28120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MFUL124B02_RS28225	COG4608	Belongs to the ABC transporter superfamily
MFUL124B02_RS28230	COG0444	Belongs to the ABC transporter superfamily
MFUL124B02_RS28250	COG0811	peptide transport
MFUL124B02_RS28260	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS28270	COG2030	dehydratase
MFUL124B02_RS28280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MFUL124B02_RS28280	COG2199	diguanylate cyclase activity
MFUL124B02_RS28285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MFUL124B02_RS28295	COG0714	Associated with various cellular activities
MFUL124B02_RS28305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MFUL124B02_RS28310	COG1193	negative regulation of DNA recombination
MFUL124B02_RS28320	COG2197	response regulator
MFUL124B02_RS28325	COG4585	Histidine kinase
MFUL124B02_RS28330	COG4585	Histidine kinase
MFUL124B02_RS28360	COG0384	phenazine biosynthesis protein PhzF
MFUL124B02_RS28365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MFUL124B02_RS28400	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MFUL124B02_RS28400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MFUL124B02_RS28410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MFUL124B02_RS28415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MFUL124B02_RS28420	COG1862	Preprotein translocase
MFUL124B02_RS28425	COG0343	queuine tRNA-ribosyltransferase activity
MFUL124B02_RS28430	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MFUL124B02_RS28435	COG2385	sporulation resulting in formation of a cellular spore
MFUL124B02_RS28460	COG1509	lysine 2,3-aminomutase activity
MFUL124B02_RS28465	COG0515	serine threonine protein kinase
MFUL124B02_RS28495	COG0194	GDP metabolic process
MFUL124B02_RS28500	COG1561	YicC-like family, N-terminal region
MFUL124B02_RS28510	COG2835	tetraacyldisaccharide 4'-kinase activity
MFUL124B02_RS28515	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MFUL124B02_RS28515	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MFUL124B02_RS28520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MFUL124B02_RS28520	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MFUL124B02_RS28525	COG1663	tetraacyldisaccharide 4'-kinase activity
MFUL124B02_RS28530	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS28540	COG1519	Transferase
MFUL124B02_RS28550	COG1132	(ABC) transporter
MFUL124B02_RS28560	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MFUL124B02_RS28565	COG0463	Glycosyl transferase, family 2
MFUL124B02_RS28570	COG2095	MarC family integral membrane protein
MFUL124B02_RS28590	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MFUL124B02_RS28595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MFUL124B02_RS28600	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MFUL124B02_RS28610	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MFUL124B02_RS28615	COG1136	(ABC) transporter
MFUL124B02_RS28625	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MFUL124B02_RS28635	COG1595	DNA-templated transcription, initiation
MFUL124B02_RS28650	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MFUL124B02_RS28650	COG0662	Cupin 2, conserved barrel domain protein
MFUL124B02_RS28655	COG1480	7TM receptor with intracellular HD hydrolase
MFUL124B02_RS28675	COG3956	TIGRFAM MazG family protein
MFUL124B02_RS28680	COG0268	Binds directly to 16S ribosomal RNA
MFUL124B02_RS28695	COG0495	leucyl-tRNA aminoacylation
MFUL124B02_RS28700	COG1629	transport
MFUL124B02_RS28710	COG2084	Dehydrogenase
MFUL124B02_RS28720	COG1131	(ABC) transporter
MFUL124B02_RS28725	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS28730	COG2201	protein-glutamate methylesterase activity
MFUL124B02_RS28735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MFUL124B02_RS28750	COG0835	chemotaxis
MFUL124B02_RS28760	COG0643	Histidine kinase
MFUL124B02_RS28760	COG0784	Response regulator, receiver
MFUL124B02_RS28760	COG2198	Histidine kinase
MFUL124B02_RS28765	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS28775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MFUL124B02_RS28780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MFUL124B02_RS28790	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MFUL124B02_RS28790	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MFUL124B02_RS28795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MFUL124B02_RS28800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MFUL124B02_RS28805	COG0698	ribose 5-phosphate isomerase
MFUL124B02_RS28810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MFUL124B02_RS28815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFUL124B02_RS28820	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS28825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MFUL124B02_RS28830	COG0416	fatty acid biosynthetic process
MFUL124B02_RS28835	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MFUL124B02_RS28840	COG1399	metal-binding, possibly nucleic acid-binding protein
MFUL124B02_RS28855	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS28860	COG5002	protein histidine kinase activity
MFUL124B02_RS28870	COG2062	phosphohistidine phosphatase, SixA
MFUL124B02_RS28880	COG0730	response to heat
MFUL124B02_RS28895	COG2204	response regulator
MFUL124B02_RS28920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MFUL124B02_RS28925	COG0573	inorganic phosphate transmembrane transporter activity
MFUL124B02_RS28930	COG0581	inorganic phosphate transmembrane transporter activity
MFUL124B02_RS28935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MFUL124B02_RS28950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MFUL124B02_RS28955	COG5002	protein histidine kinase activity
MFUL124B02_RS28955	COG2205	protein histidine kinase activity
MFUL124B02_RS28955	COG0784	Response regulator, receiver
MFUL124B02_RS28960	COG1253	flavin adenine dinucleotide binding
MFUL124B02_RS28965	COG2197	response regulator
MFUL124B02_RS28970	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MFUL124B02_RS29050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MFUL124B02_RS29055	COG4208	sulfate ABC transporter
MFUL124B02_RS29060	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MFUL124B02_RS29085	COG0542	response to heat
MFUL124B02_RS29155	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MFUL124B02_RS29190	COG0351	phosphomethylpyrimidine kinase
MFUL124B02_RS29195	COG3795	YCII-related domain
MFUL124B02_RS29200	COG4941	Belongs to the sigma-70 factor family
MFUL124B02_RS29235	COG0288	reversible hydration of carbon dioxide
MFUL124B02_RS29255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MFUL124B02_RS29265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MFUL124B02_RS29320	COG3063	Type IV pilus biogenesis stability protein PilW
MFUL124B02_RS29340	COG1324	tolerance protein
MFUL124B02_RS29345	COG0542	response to heat
MFUL124B02_RS29355	COG1652	LysM domain
MFUL124B02_RS29370	COG1131	(ABC) transporter
MFUL124B02_RS29395	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MFUL124B02_RS29420	COG1595	DNA-templated transcription, initiation
MFUL124B02_RS29440	COG2223	nitrite transmembrane transporter activity
MFUL124B02_RS29455	COG1758	RNA polymerase activity
MFUL124B02_RS29475	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MFUL124B02_RS29480	COG0459	protein refolding
MFUL124B02_RS29495	COG3829	transcription factor binding
MFUL124B02_RS29505	COG1196	nuclear chromosome segregation
MFUL124B02_RS29515	COG1253	flavin adenine dinucleotide binding
MFUL124B02_RS29525	COG2843	Capsule synthesis protein
MFUL124B02_RS29530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MFUL124B02_RS29535	COG2890	protein-(glutamine-N5) methyltransferase activity
MFUL124B02_RS29540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFUL124B02_RS29590	COG0523	cobalamin synthesis protein
MFUL124B02_RS29595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MFUL124B02_RS29605	COG2204	response regulator
MFUL124B02_RS29610	COG2205	protein histidine kinase activity
MFUL124B02_RS29615	COG0659	secondary active sulfate transmembrane transporter activity
MFUL124B02_RS29660	COG3209	COG3209 Rhs family protein
MFUL124B02_RS29690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MFUL124B02_RS29700	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS29770	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MFUL124B02_RS29805	COG3220	belongs to the UPF0276 family
MFUL124B02_RS29840	COG0270	DNA (cytosine-5-)-methyltransferase activity
MFUL124B02_RS29865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MFUL124B02_RS29870	COG3800	Transcriptional regulator
MFUL124B02_RS29870	COG1396	sequence-specific DNA binding
MFUL124B02_RS29885	COG0730	response to heat
MFUL124B02_RS29895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MFUL124B02_RS29910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MFUL124B02_RS29910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MFUL124B02_RS29915	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MFUL124B02_RS29925	COG2255	four-way junction helicase activity
MFUL124B02_RS29940	COG0632	four-way junction helicase activity
MFUL124B02_RS29945	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MFUL124B02_RS29950	COG0217	transcriptional regulatory protein
MFUL124B02_RS29955	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS29975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MFUL124B02_RS29985	COG0430	RNA-3'-phosphate cyclase activity
MFUL124B02_RS29995	COG1690	Belongs to the RtcB family
MFUL124B02_RS30000	COG4650	regulator
MFUL124B02_RS30075	COG1104	cysteine desulfurase activity
MFUL124B02_RS30080	COG0822	iron-sulfur transferase activity
MFUL124B02_RS30085	COG0316	Belongs to the HesB IscA family
MFUL124B02_RS30090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MFUL124B02_RS30100	COG0633	Ferredoxin
MFUL124B02_RS30145	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MFUL124B02_RS30155	COG1304	FMN binding
MFUL124B02_RS30200	COG1846	Transcriptional regulator
MFUL124B02_RS30225	COG2066	Belongs to the glutaminase family
MFUL124B02_RS30240	COG2133	pyrroloquinoline quinone binding
MFUL124B02_RS30260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS30265	COG1335	isochorismatase
MFUL124B02_RS30275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFUL124B02_RS30295	COG0720	synthase
MFUL124B02_RS30305	COG5002	protein histidine kinase activity
MFUL124B02_RS30310	COG0612	Peptidase, M16
MFUL124B02_RS30345	COG1012	belongs to the aldehyde dehydrogenase family
MFUL124B02_RS30350	COG3284	Transcriptional regulator
MFUL124B02_RS30380	COG3239	Fatty acid desaturase
MFUL124B02_RS30390	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS30400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MFUL124B02_RS30415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MFUL124B02_RS30415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFUL124B02_RS30420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFUL124B02_RS30475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MFUL124B02_RS30490	COG2088	sporulation resulting in formation of a cellular spore
MFUL124B02_RS30495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFUL124B02_RS30500	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MFUL124B02_RS30505	COG0193	aminoacyl-tRNA hydrolase activity
MFUL124B02_RS30510	COG0360	Binds together with S18 to 16S ribosomal RNA
MFUL124B02_RS30515	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MFUL124B02_RS30520	COG0359	binds to the 23S rRNA
MFUL124B02_RS30530	COG3275	phosphorelay sensor kinase activity
MFUL124B02_RS30535	COG3279	Response regulator of the LytR AlgR family
MFUL124B02_RS30545	COG0351	phosphomethylpyrimidine kinase
MFUL124B02_RS30545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MFUL124B02_RS30545	COG0352	thiamine-phosphate diphosphorylase activity
MFUL124B02_RS30550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MFUL124B02_RS30555	COG0352	thiamine-phosphate diphosphorylase activity
MFUL124B02_RS30580	COG0542	response to heat
MFUL124B02_RS30600	COG1309	transcriptional regulator
MFUL124B02_RS30610	COG1473	amidohydrolase
MFUL124B02_RS30640	COG5002	protein histidine kinase activity
MFUL124B02_RS30645	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS30665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MFUL124B02_RS30670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MFUL124B02_RS30680	COG0165	Argininosuccinate lyase
MFUL124B02_RS30685	COG0137	argininosuccinate synthase activity
MFUL124B02_RS30695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MFUL124B02_RS30740	COG0402	S-adenosylhomocysteine deaminase activity
MFUL124B02_RS30760	COG0789	Transcriptional regulator
MFUL124B02_RS30785	COG2204	response regulator
MFUL124B02_RS30790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS30795	COG3186	Phenylalanine-4-hydroxylase
MFUL124B02_RS30830	COG4948	Mandelate Racemase Muconate Lactonizing
MFUL124B02_RS30835	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MFUL124B02_RS30845	COG0183	Belongs to the thiolase family
MFUL124B02_RS30850	COG1250	3-hydroxyacyl-CoA dehydrogenase
MFUL124B02_RS30850	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS30865	COG0254	rRNA binding
MFUL124B02_RS30880	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MFUL124B02_RS30885	COG2201	protein-glutamate methylesterase activity
MFUL124B02_RS30915	COG2885	chlorophyll binding
MFUL124B02_RS30920	COG2204	response regulator
MFUL124B02_RS30955	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MFUL124B02_RS30990	COG2267	carboxylic ester hydrolase activity
MFUL124B02_RS30995	COG2135	peptidase activity
MFUL124B02_RS31015	COG3279	Response regulator of the LytR AlgR family
MFUL124B02_RS31020	COG3275	phosphorelay sensor kinase activity
MFUL124B02_RS31030	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MFUL124B02_RS31070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFUL124B02_RS31080	COG1966	Carbon starvation protein
MFUL124B02_RS31085	COG2879	small protein
MFUL124B02_RS31110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MFUL124B02_RS31145	COG5000	phosphorelay sensor kinase activity
MFUL124B02_RS31160	COG2205	protein histidine kinase activity
MFUL124B02_RS31160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MFUL124B02_RS31185	COG3047	cAMP biosynthetic process
MFUL124B02_RS31185	COG2885	chlorophyll binding
MFUL124B02_RS31200	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MFUL124B02_RS31200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MFUL124B02_RS31205	COG0252	asparaginase activity
MFUL124B02_RS31225	COG1610	YqeY-like protein
MFUL124B02_RS31240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MFUL124B02_RS31250	COG1522	sequence-specific DNA binding
MFUL124B02_RS31255	COG0339	signal peptide processing
MFUL124B02_RS31275	COG1595	DNA-templated transcription, initiation
MFUL124B02_RS31305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MFUL124B02_RS31310	COG0835	chemotaxis
MFUL124B02_RS31320	COG2198	Histidine kinase
MFUL124B02_RS31320	COG0643	Histidine kinase
MFUL124B02_RS31380	COG0300	oxidoreductase activity
MFUL124B02_RS31385	COG1215	transferase activity, transferring glycosyl groups
MFUL124B02_RS31490	COG0737	Belongs to the 5'-nucleotidase family
MFUL124B02_RS31515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFUL124B02_RS31525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MFUL124B02_RS31640	COG1278	Cold shock
MFUL124B02_RS31655	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS31680	COG0109	protoheme IX farnesyltransferase activity
MFUL124B02_RS31700	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS31705	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS31715	COG0737	Belongs to the 5'-nucleotidase family
MFUL124B02_RS31770	COG0543	2 iron, 2 sulfur cluster binding
MFUL124B02_RS31770	COG0493	'glutamate synthase
MFUL124B02_RS31785	COG1965	Belongs to the frataxin family
MFUL124B02_RS31795	COG0233	cytoplasmic translational termination
MFUL124B02_RS31800	COG0528	UMP kinase activity
MFUL124B02_RS31805	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MFUL124B02_RS31810	COG0052	Belongs to the universal ribosomal protein uS2 family
MFUL124B02_RS31815	COG0653	protein targeting
MFUL124B02_RS31820	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
MFUL124B02_RS31830	COG0739	heme binding
MFUL124B02_RS31835	COG0631	protein serine/threonine phosphatase activity
MFUL124B02_RS31840	COG0497	DNA recombination
MFUL124B02_RS31845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MFUL124B02_RS31855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MFUL124B02_RS31870	COG2814	Major facilitator Superfamily
MFUL124B02_RS31875	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MFUL124B02_RS31885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MFUL124B02_RS31890	COG0737	Belongs to the 5'-nucleotidase family
MFUL124B02_RS31905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFUL124B02_RS31910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MFUL124B02_RS31925	COG3706	GGDEF domain
MFUL124B02_RS31930	COG0463	Glycosyl transferase, family 2
MFUL124B02_RS31940	COG2264	protein methyltransferase activity
MFUL124B02_RS31950	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS31950	COG1250	3-hydroxyacyl-CoA dehydrogenase
MFUL124B02_RS31965	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MFUL124B02_RS31970	COG0366	Alpha amylase catalytic
MFUL124B02_RS31985	COG3842	ATPase activity
MFUL124B02_RS31995	COG3833	ABC-type maltose transport systems, permease component
MFUL124B02_RS32035	COG0702	epimerase
MFUL124B02_RS32050	COG1902	pentaerythritol trinitrate reductase activity
MFUL124B02_RS32065	COG3321	synthase
MFUL124B02_RS32065	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS32065	COG0604	alcohol dehydrogenase
MFUL124B02_RS32070	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS32075	COG3795	YCII-related domain
MFUL124B02_RS32085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MFUL124B02_RS32095	COG0515	serine threonine protein kinase
MFUL124B02_RS32130	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS32150	COG1280	lysine exporter protein (LysE YggA)
MFUL124B02_RS32165	COG2311	Membrane
MFUL124B02_RS32185	COG4676	Protein conserved in bacteria
MFUL124B02_RS32200	COG2321	neutral zinc metallopeptidase
MFUL124B02_RS32205	COG0612	Peptidase, M16
MFUL124B02_RS32220	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MFUL124B02_RS32230	COG2205	protein histidine kinase activity
MFUL124B02_RS32230	COG0784	Response regulator, receiver
MFUL124B02_RS32235	COG0784	Response regulator, receiver
MFUL124B02_RS32235	COG2205	protein histidine kinase activity
MFUL124B02_RS32265	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MFUL124B02_RS32280	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS32310	COG1126	abc transporter atp-binding protein
MFUL124B02_RS32320	COG2204	response regulator
MFUL124B02_RS32325	COG4191	Histidine kinase
MFUL124B02_RS32330	COG2124	cytochrome p450
MFUL124B02_RS32335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MFUL124B02_RS32335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MFUL124B02_RS32340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MFUL124B02_RS32360	COG0210	DNA helicase
MFUL124B02_RS32370	COG1032	radical SAM domain protein
MFUL124B02_RS32390	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MFUL124B02_RS32460	COG0588	phosphoglycerate mutase activity
MFUL124B02_RS32475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MFUL124B02_RS32495	COG3278	Belongs to the heme-copper respiratory oxidase family
MFUL124B02_RS32555	COG0183	Belongs to the thiolase family
MFUL124B02_RS32565	COG0653	protein targeting
MFUL124B02_RS32575	COG0673	inositol 2-dehydrogenase activity
MFUL124B02_RS32615	COG0437	4 iron, 4 sulfur cluster binding
MFUL124B02_RS32640	COG1858	cytochrome C peroxidase
MFUL124B02_RS32655	COG3030	protein affecting phage T7 exclusion by the F plasmid
MFUL124B02_RS32675	COG1929	Belongs to the glycerate kinase type-1 family
MFUL124B02_RS32685	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MFUL124B02_RS32720	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MFUL124B02_RS32765	COG0457	Tetratricopeptide repeat
MFUL124B02_RS32765	COG0705	Rhomboid family
MFUL124B02_RS32775	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS32780	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS32790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MFUL124B02_RS32805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MFUL124B02_RS32810	COG1181	Belongs to the D-alanine--D-alanine ligase family
MFUL124B02_RS32815	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MFUL124B02_RS32820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MFUL124B02_RS32825	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MFUL124B02_RS32835	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MFUL124B02_RS32840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MFUL124B02_RS32845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MFUL124B02_RS32850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MFUL124B02_RS32860	COG3116	cell division
MFUL124B02_RS32865	COG0275	rRNA processing
MFUL124B02_RS32875	COG2001	Belongs to the MraZ family
MFUL124B02_RS32885	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS32905	COG0515	serine threonine protein kinase
MFUL124B02_RS32950	COG1309	transcriptional regulator
MFUL124B02_RS32985	COG1012	belongs to the aldehyde dehydrogenase family
MFUL124B02_RS32990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MFUL124B02_RS32990	COG0519	Catalyzes the synthesis of GMP from XMP
MFUL124B02_RS33010	COG0628	permease
MFUL124B02_RS33025	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MFUL124B02_RS33030	COG1254	Belongs to the acylphosphatase family
MFUL124B02_RS33045	COG1959	2 iron, 2 sulfur cluster binding
MFUL124B02_RS33045	COG1295	ribonuclease BN
MFUL124B02_RS33060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MFUL124B02_RS33075	COG4790	Type iii secretion
MFUL124B02_RS33115	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS33170	COG0714	Associated with various cellular activities
MFUL124B02_RS33175	COG2267	carboxylic ester hydrolase activity
MFUL124B02_RS33215	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS33290	COG0668	transmembrane transport
MFUL124B02_RS33300	COG0737	Belongs to the 5'-nucleotidase family
MFUL124B02_RS33305	COG1388	LysM domain
MFUL124B02_RS33305	COG1705	Flagellar rod assembly protein muramidase FlgJ
MFUL124B02_RS33320	COG0515	serine threonine protein kinase
MFUL124B02_RS33335	COG1136	(ABC) transporter
MFUL124B02_RS33335	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS33375	COG0402	S-adenosylhomocysteine deaminase activity
MFUL124B02_RS33380	COG0295	cytidine deaminase activity
MFUL124B02_RS33395	COG1309	transcriptional regulator
MFUL124B02_RS33400	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS33410	COG1744	ABC transporter substrate-binding protein PnrA-like
MFUL124B02_RS33415	COG3845	ABC transporter
MFUL124B02_RS33420	COG4603	Belongs to the binding-protein-dependent transport system permease family
MFUL124B02_RS33425	COG1079	Belongs to the binding-protein-dependent transport system permease family
MFUL124B02_RS33430	COG4191	Histidine kinase
MFUL124B02_RS33440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MFUL124B02_RS33450	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MFUL124B02_RS33455	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MFUL124B02_RS33460	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MFUL124B02_RS33510	COG0552	protein localization to endoplasmic reticulum
MFUL124B02_RS33535	COG1215	transferase activity, transferring glycosyl groups
MFUL124B02_RS33540	COG1181	Belongs to the D-alanine--D-alanine ligase family
MFUL124B02_RS33555	COG0793	Belongs to the peptidase S41A family
MFUL124B02_RS33565	COG4942	peptidase
MFUL124B02_RS33570	COG2177	Part of the ABC transporter FtsEX involved in
MFUL124B02_RS33575	COG2884	Cell division ATP-binding protein ftsE
MFUL124B02_RS33580	COG0471	metal ion transport
MFUL124B02_RS33595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MFUL124B02_RS33605	COG0811	peptide transport
MFUL124B02_RS33620	COG0823	Involved in the tonB-independent uptake of proteins
MFUL124B02_RS33625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MFUL124B02_RS33630	COG0248	Ppx GppA phosphatase
MFUL124B02_RS33635	COG2814	Major facilitator Superfamily
MFUL124B02_RS33650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MFUL124B02_RS33660	COG3409	Peptidoglycan-binding domain 1 protein
MFUL124B02_RS33660	COG3267	Type II secretory pathway component ExeA
MFUL124B02_RS33670	COG0439	Biotin carboxylase
MFUL124B02_RS33675	COG0511	ligase activity, forming carbon-carbon bonds
MFUL124B02_RS33680	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFUL124B02_RS33720	COG2204	response regulator
MFUL124B02_RS33725	COG4191	Histidine kinase
MFUL124B02_RS33730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MFUL124B02_RS33735	COG4968	Prepilin-type N-terminal cleavage methylation domain
MFUL124B02_RS33745	COG1131	(ABC) transporter
MFUL124B02_RS33770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MFUL124B02_RS33785	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MFUL124B02_RS33795	COG3852	Histidine kinase
MFUL124B02_RS33800	COG1459	type II secretion system
MFUL124B02_RS33810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MFUL124B02_RS33820	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MFUL124B02_RS33845	COG1199	ATP-dependent helicase activity
MFUL124B02_RS33870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MFUL124B02_RS33885	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS33895	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MFUL124B02_RS33905	COG0793	Belongs to the peptidase S41A family
MFUL124B02_RS33915	COG0584	glycerophosphoryl diester phosphodiesterase
MFUL124B02_RS33920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MFUL124B02_RS33945	COG1192	Involved in chromosome partitioning
MFUL124B02_RS33985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MFUL124B02_RS33995	COG2766	serine protein kinase
MFUL124B02_RS34000	COG2718	Belongs to the UPF0229 family
MFUL124B02_RS34005	COG2719	SpoVR family
MFUL124B02_RS34040	COG0739	heme binding
MFUL124B02_RS34050	COG0058	SHG alpha-glucan phosphorylase activity
MFUL124B02_RS34070	COG4604	ABC transporter, ATP-binding protein
MFUL124B02_RS34075	COG4605	iron ion homeostasis
MFUL124B02_RS34080	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFUL124B02_RS34085	COG4607	ABC-type enterochelin transport system periplasmic component
MFUL124B02_RS34090	COG0339	signal peptide processing
MFUL124B02_RS34100	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS34105	COG0826	peptidase U32
MFUL124B02_RS34110	COG1605	Chorismate mutase
MFUL124B02_RS34110	COG0287	Prephenate dehydrogenase
MFUL124B02_RS34115	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS34120	COG0587	DNA-directed DNA polymerase activity
MFUL124B02_RS34135	COG0667	Aldo Keto reductase
MFUL124B02_RS34140	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MFUL124B02_RS34195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MFUL124B02_RS34225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MFUL124B02_RS34235	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFUL124B02_RS34260	COG2032	superoxide dismutase activity
MFUL124B02_RS34310	COG0513	Belongs to the DEAD box helicase family
MFUL124B02_RS34320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MFUL124B02_RS34325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MFUL124B02_RS34340	COG2353	YceI-like domain
MFUL124B02_RS34345	COG3384	dioxygenase
MFUL124B02_RS34370	COG0183	Belongs to the thiolase family
MFUL124B02_RS34400	COG2351	hydroxyisourate hydrolase activity
MFUL124B02_RS34410	COG4266	Belongs to the allantoicase family
MFUL124B02_RS34415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MFUL124B02_RS34420	COG2072	flavoprotein involved in K transport
MFUL124B02_RS34425	COG1012	belongs to the aldehyde dehydrogenase family
MFUL124B02_RS34455	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS34460	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS34505	COG2169	Transcriptional regulator
MFUL124B02_RS34505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MFUL124B02_RS34515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MFUL124B02_RS34530	COG0805	protein transport
MFUL124B02_RS34560	COG3119	arylsulfatase activity
MFUL124B02_RS34570	COG0300	oxidoreductase activity
MFUL124B02_RS34575	COG0284	orotidine-5'-phosphate decarboxylase activity
MFUL124B02_RS34585	COG0564	pseudouridine synthase activity
MFUL124B02_RS34620	COG1793	dna ligase
MFUL124B02_RS34620	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MFUL124B02_RS34645	COG2086	electron transfer activity
MFUL124B02_RS34650	COG1960	acyl-CoA dehydrogenase activity
MFUL124B02_RS34655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MFUL124B02_RS34660	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MFUL124B02_RS34660	COG0517	IMP dehydrogenase activity
MFUL124B02_RS34670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MFUL124B02_RS34675	COG0179	Fumarylacetoacetate (FAA) hydrolase
MFUL124B02_RS34680	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MFUL124B02_RS34685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MFUL124B02_RS34720	COG1295	ribonuclease BN
MFUL124B02_RS34740	COG2342	PFAM TM1410 hypothetical-related protein
MFUL124B02_RS34745	COG1476	TRANSCRIPTIONal
MFUL124B02_RS34755	COG0697	spore germination
MFUL124B02_RS34765	COG2096	Adenosyltransferase
MFUL124B02_RS34770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MFUL124B02_RS34775	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFUL124B02_RS34795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MFUL124B02_RS34800	COG1078	dGTPase activity
MFUL124B02_RS34805	COG1181	Belongs to the D-alanine--D-alanine ligase family
MFUL124B02_RS34820	COG1331	Highly conserved protein containing a thioredoxin domain
MFUL124B02_RS34880	COG0515	serine threonine protein kinase
MFUL124B02_RS34900	COG0037	tRNA processing
MFUL124B02_RS34930	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MFUL124B02_RS34940	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MFUL124B02_RS34950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MFUL124B02_RS34950	COG1796	DNA polymerase
MFUL124B02_RS34970	COG1131	(ABC) transporter
MFUL124B02_RS34975	COG2264	protein methyltransferase activity
MFUL124B02_RS35010	COG4191	Histidine kinase
MFUL124B02_RS35025	COG0116	Belongs to the methyltransferase superfamily
MFUL124B02_RS35025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MFUL124B02_RS35040	COG0531	amino acid
MFUL124B02_RS35045	COG0564	pseudouridine synthase activity
MFUL124B02_RS35075	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MFUL124B02_RS35080	COG0542	response to heat
MFUL124B02_RS35090	COG2201	protein-glutamate methylesterase activity
MFUL124B02_RS35115	COG5002	protein histidine kinase activity
MFUL124B02_RS35115	COG2205	protein histidine kinase activity
MFUL124B02_RS35115	COG0784	Response regulator, receiver
MFUL124B02_RS35120	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MFUL124B02_RS35125	COG0567	Dehydrogenase, E1 component
MFUL124B02_RS35130	COG0508	dehydrogenase complex catalyzes the overall conversion of
MFUL124B02_RS35135	COG1278	Cold shock
MFUL124B02_RS35155	COG1230	cation diffusion facilitator family transporter
MFUL124B02_RS35175	COG2814	Major facilitator Superfamily
MFUL124B02_RS35190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MFUL124B02_RS35195	COG2815	serine threonine protein kinase
MFUL124B02_RS35195	COG0515	serine threonine protein kinase
MFUL124B02_RS35200	COG4771	TonB-dependent receptor
MFUL124B02_RS35215	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MFUL124B02_RS35220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MFUL124B02_RS35240	COG0326	Molecular chaperone. Has ATPase activity
MFUL124B02_RS35250	COG1233	COG1233 Phytoene dehydrogenase and related
MFUL124B02_RS35255	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MFUL124B02_RS35260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MFUL124B02_RS35265	COG0134	indole-3-glycerol-phosphate synthase activity
MFUL124B02_RS35270	COG0135	phosphoribosylanthranilate isomerase activity
MFUL124B02_RS35275	COG0133	tryptophan synthase activity
MFUL124B02_RS35280	COG0159	tryptophan synthase activity
MFUL124B02_RS35305	COG0406	alpha-ribazole phosphatase activity
MFUL124B02_RS35330	COG1793	dna ligase
MFUL124B02_RS35335	COG1201	RNA secondary structure unwinding
MFUL124B02_RS35355	COG0437	4 iron, 4 sulfur cluster binding
MFUL124B02_RS35390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MFUL124B02_RS35400	COG1845	cytochrome c oxidase, subunit III
MFUL124B02_RS35490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MFUL124B02_RS35495	COG3227	Zinc metalloprotease (Elastase)
MFUL124B02_RS35515	COG3214	Protein conserved in bacteria
MFUL124B02_RS35530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MFUL124B02_RS35535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MFUL124B02_RS35545	COG1678	Uncharacterized ACR, COG1678
MFUL124B02_RS35555	COG2205	protein histidine kinase activity
MFUL124B02_RS35595	COG1309	transcriptional regulator
MFUL124B02_RS35610	COG0322	excinuclease ABC activity
MFUL124B02_RS35620	COG0004	ammonium transporteR
MFUL124B02_RS35655	COG0590	tRNA wobble adenosine to inosine editing
MFUL124B02_RS35655	COG0037	tRNA processing
MFUL124B02_RS35680	COG2217	Heavy metal translocating P-type atpase
MFUL124B02_RS35710	COG1760	l-serine dehydratase
MFUL124B02_RS35730	COG0753	catalase activity
MFUL124B02_RS35730	COG0693	protein deglycase activity
MFUL124B02_RS35785	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MFUL124B02_RS35795	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS35930	COG2255	four-way junction helicase activity
MFUL124B02_RS35960	COG2204	response regulator
MFUL124B02_RS35985	COG3781	membrane
MFUL124B02_RS36025	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS36045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFUL124B02_RS36065	COG1846	Transcriptional regulator
MFUL124B02_RS36105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MFUL124B02_RS36110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MFUL124B02_RS36110	COG2111	Na H antiporter
MFUL124B02_RS36115	COG0651	ATP synthesis coupled electron transport
MFUL124B02_RS36120	COG0651	ATP synthesis coupled electron transport
MFUL124B02_RS36130	COG2111	Na H antiporter
MFUL124B02_RS36130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MFUL124B02_RS36135	COG1320	monovalent cation:proton antiporter activity
MFUL124B02_RS36150	COG3033	Beta-eliminating lyase
MFUL124B02_RS36165	COG0596	Alpha beta hydrolase
MFUL124B02_RS36185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MFUL124B02_RS36195	COG0288	reversible hydration of carbon dioxide
MFUL124B02_RS36205	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS36245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MFUL124B02_RS36250	COG3959	Transketolase, thiamine diphosphate binding domain
MFUL124B02_RS36270	COG4975	Glucose uptake
MFUL124B02_RS36280	COG0625	glutathione transferase activity
MFUL124B02_RS36295	COG3781	membrane
MFUL124B02_RS36300	COG0534	Mate efflux family protein
MFUL124B02_RS36315	COG0667	Aldo Keto reductase
MFUL124B02_RS36395	COG1595	DNA-templated transcription, initiation
MFUL124B02_RS36630	COG2433	Pfam Transposase IS66
MFUL124B02_RS36635	COG4372	Transposase
MFUL124B02_RS36650	COG3436	PFAM IS66 Orf2 family protein
MFUL124B02_RS36730	COG4372	Transposase
MFUL124B02_RS36735	COG4974	Belongs to the 'phage' integrase family
MFUL124B02_RS36750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MFUL124B02_RS36755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MFUL124B02_RS36760	COG0469	pyruvate kinase activity
MFUL124B02_RS36780	COG2723	6-phospho-beta-galactosidase activity
MFUL124B02_RS36785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFUL124B02_RS36790	COG1994	Peptidase M50
MFUL124B02_RS36790	COG0517	IMP dehydrogenase activity
MFUL124B02_RS36820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MFUL124B02_RS36830	COG0515	serine threonine protein kinase
MFUL124B02_RS36840	COG3394	polysaccharide catabolic process
MFUL124B02_RS36850	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MFUL124B02_RS36860	COG2815	serine threonine protein kinase
MFUL124B02_RS36860	COG0515	serine threonine protein kinase
MFUL124B02_RS36875	COG0248	Ppx GppA phosphatase
MFUL124B02_RS36885	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MFUL124B02_RS36890	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS36925	COG2910	NAD(P)H-binding
MFUL124B02_RS36940	COG0473	3-isopropylmalate dehydrogenase activity
MFUL124B02_RS36945	COG0023	Translation Initiation Factor
MFUL124B02_RS36960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MFUL124B02_RS37040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MFUL124B02_RS37045	COG0277	FAD linked oxidase domain protein
MFUL124B02_RS37105	COG0515	serine threonine protein kinase
MFUL124B02_RS37105	COG2815	serine threonine protein kinase
MFUL124B02_RS37115	COG3239	Fatty acid desaturase
MFUL124B02_RS37155	COG0741	lytic transglycosylase activity
MFUL124B02_RS37155	COG0739	heme binding
MFUL124B02_RS37155	COG1196	nuclear chromosome segregation
MFUL124B02_RS37180	COG1858	cytochrome C peroxidase
MFUL124B02_RS37205	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS37235	COG1408	metallophosphoesterase
MFUL124B02_RS37240	COG0235	Class ii aldolase
MFUL124B02_RS37245	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MFUL124B02_RS37250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MFUL124B02_RS37255	COG0640	Transcriptional regulator
MFUL124B02_RS37290	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS37300	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS37300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MFUL124B02_RS37300	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS37300	COG0300	oxidoreductase activity
MFUL124B02_RS37300	COG3321	synthase
MFUL124B02_RS37320	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS37335	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MFUL124B02_RS37340	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MFUL124B02_RS37395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MFUL124B02_RS37400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFUL124B02_RS37425	COG0737	Belongs to the 5'-nucleotidase family
MFUL124B02_RS37425	COG4085	toxin activity
MFUL124B02_RS37425	COG1525	nuclease
MFUL124B02_RS37430	COG1525	nuclease
MFUL124B02_RS37430	COG0737	Belongs to the 5'-nucleotidase family
MFUL124B02_RS37430	COG4085	toxin activity
MFUL124B02_RS37440	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MFUL124B02_RS37445	COG1063	alcohol dehydrogenase
MFUL124B02_RS37450	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS37455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MFUL124B02_RS37455	COG0574	Belongs to the PEP-utilizing enzyme family
MFUL124B02_RS37465	COG0071	Belongs to the small heat shock protein (HSP20) family
MFUL124B02_RS37475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MFUL124B02_RS37490	COG0740	serine-type endopeptidase activity
MFUL124B02_RS37495	COG0114	fumarate hydratase activity
MFUL124B02_RS37505	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MFUL124B02_RS37510	COG2224	Isocitrate lyase
MFUL124B02_RS37570	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS37575	COG0596	Alpha beta hydrolase
MFUL124B02_RS37605	COG3138	arginine N-succinyltransferase
MFUL124B02_RS37675	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MFUL124B02_RS37690	COG2094	Belongs to the DNA glycosylase MPG family
MFUL124B02_RS37695	COG1640	4-alpha-glucanotransferase
MFUL124B02_RS37755	COG1131	(ABC) transporter
MFUL124B02_RS37765	COG0714	Associated with various cellular activities
MFUL124B02_RS37775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MFUL124B02_RS37790	COG0667	Aldo Keto reductase
MFUL124B02_RS37810	COG2133	pyrroloquinoline quinone binding
MFUL124B02_RS37815	COG0811	peptide transport
MFUL124B02_RS37855	COG0546	phosphoglycolate phosphatase activity
MFUL124B02_RS37875	COG0741	lytic transglycosylase activity
MFUL124B02_RS37875	COG0739	heme binding
MFUL124B02_RS37875	COG1196	nuclear chromosome segregation
MFUL124B02_RS37900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFUL124B02_RS37965	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MFUL124B02_RS37970	COG1940	carbohydrate kinase activity
MFUL124B02_RS38010	COG1968	undecaprenyl-diphosphatase activity
MFUL124B02_RS38015	COG3012	SEC-C Motif Domain Protein
MFUL124B02_RS38040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MFUL124B02_RS38065	COG1285	pathogenesis
MFUL124B02_RS38075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MFUL124B02_RS38085	COG3716	PTS system mannose fructose sorbose family IID component
MFUL124B02_RS38090	COG3715	PTS system
MFUL124B02_RS38095	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MFUL124B02_RS38100	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MFUL124B02_RS38100	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MFUL124B02_RS38105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MFUL124B02_RS38110	COG4104	PAAR repeat-containing protein
MFUL124B02_RS38150	COG4771	TonB-dependent receptor
MFUL124B02_RS38180	COG0747	negative chemotaxis
MFUL124B02_RS38185	COG0601	transmembrane transport
MFUL124B02_RS38190	COG0444	Belongs to the ABC transporter superfamily
MFUL124B02_RS38195	COG4608	Belongs to the ABC transporter superfamily
MFUL124B02_RS38235	COG0657	acetylesterase activity
MFUL124B02_RS38240	COG2072	flavoprotein involved in K transport
MFUL124B02_RS38245	COG1971	Probably functions as a manganese efflux pump
MFUL124B02_RS38250	COG1660	Displays ATPase and GTPase activities
MFUL124B02_RS38255	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MFUL124B02_RS38260	COG0537	adenosine 5'-monophosphoramidase activity
MFUL124B02_RS38275	COG1966	Carbon starvation protein
MFUL124B02_RS38280	COG0515	serine threonine protein kinase
MFUL124B02_RS38310	COG4206	TonB-dependent receptor
MFUL124B02_RS38350	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MFUL124B02_RS38355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MFUL124B02_RS38405	COG1506	peptidase
MFUL124B02_RS38405	COG0823	Involved in the tonB-independent uptake of proteins
MFUL124B02_RS38410	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MFUL124B02_RS38425	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS38460	COG0714	Associated with various cellular activities
MFUL124B02_RS38480	COG0513	Belongs to the DEAD box helicase family
MFUL124B02_RS38485	COG3189	MarR family transcriptional regulator
MFUL124B02_RS38490	COG1472	Belongs to the glycosyl hydrolase 3 family
MFUL124B02_RS38505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MFUL124B02_RS38520	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS38535	COG0546	phosphoglycolate phosphatase activity
MFUL124B02_RS38535	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MFUL124B02_RS38540	COG0277	FAD linked oxidase domain protein
MFUL124B02_RS38555	COG0667	Aldo Keto reductase
MFUL124B02_RS38570	COG2137	regulation of response to DNA damage stimulus
MFUL124B02_RS38580	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS38610	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS38615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFUL124B02_RS38620	COG1755	Isoprenylcysteine carboxyl methyltransferase
MFUL124B02_RS38645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MFUL124B02_RS38655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MFUL124B02_RS38660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MFUL124B02_RS38675	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MFUL124B02_RS38680	COG4149	molybdate abc transporter
MFUL124B02_RS38685	COG0725	ABC transporter, periplasmic molybdate-binding protein
MFUL124B02_RS38690	COG1846	Transcriptional regulator
MFUL124B02_RS38695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS38700	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MFUL124B02_RS38735	COG0442	prolyl-tRNA aminoacylation
MFUL124B02_RS38745	COG1988	membrane-bound metal-dependent
MFUL124B02_RS38755	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MFUL124B02_RS38765	COG4106	trans-aconitate 2-methyltransferase activity
MFUL124B02_RS38820	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS38825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MFUL124B02_RS38895	COG3852	Histidine kinase
MFUL124B02_RS38910	COG3647	Membrane
MFUL124B02_RS38925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFUL124B02_RS38940	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MFUL124B02_RS38945	COG1691	(AIR) carboxylase
MFUL124B02_RS38965	COG2201	protein-glutamate methylesterase activity
MFUL124B02_RS38970	COG0835	chemotaxis
MFUL124B02_RS38980	COG0840	transmembrane signaling receptor activity
MFUL124B02_RS38985	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MFUL124B02_RS39010	COG0640	Transcriptional regulator
MFUL124B02_RS39025	COG0784	Response regulator, receiver
MFUL124B02_RS39025	COG5002	protein histidine kinase activity
MFUL124B02_RS39025	COG2205	protein histidine kinase activity
MFUL124B02_RS39030	COG1100	Small GTP-binding protein
MFUL124B02_RS39080	COG0024	Methionine aminopeptidase
MFUL124B02_RS39100	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS39110	COG4206	TonB-dependent receptor
MFUL124B02_RS39125	COG1199	ATP-dependent helicase activity
MFUL124B02_RS39150	COG0546	phosphoglycolate phosphatase activity
MFUL124B02_RS39165	COG1597	lipid kinase activity
MFUL124B02_RS39175	COG1420	regulation of RNA biosynthetic process
MFUL124B02_RS39180	COG0697	spore germination
MFUL124B02_RS39255	COG3550	peptidyl-serine autophosphorylation
MFUL124B02_RS39260	COG0693	protein deglycase activity
MFUL124B02_RS39270	COG3550	peptidyl-serine autophosphorylation
MFUL124B02_RS39275	COG2133	pyrroloquinoline quinone binding
MFUL124B02_RS39280	COG0025	NhaP-type Na H and K H
MFUL124B02_RS39285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS39310	COG2205	protein histidine kinase activity
MFUL124B02_RS39320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFUL124B02_RS39365	COG0408	coproporphyrinogen oxidase activity
MFUL124B02_RS39375	COG0408	coproporphyrinogen oxidase activity
MFUL124B02_RS39405	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS39430	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MFUL124B02_RS39440	COG2154	pterin-4-alpha-carbinolamine dehydratase
MFUL124B02_RS39470	COG3279	Response regulator of the LytR AlgR family
MFUL124B02_RS39475	COG3275	phosphorelay sensor kinase activity
MFUL124B02_RS39480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MFUL124B02_RS39500	COG2171	N-acyltransferase activity
MFUL124B02_RS39530	COG1215	transferase activity, transferring glycosyl groups
MFUL124B02_RS39550	COG4651	solute:proton antiporter activity
MFUL124B02_RS39550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MFUL124B02_RS39565	COG1077	Cell shape determining protein MreB Mrl
MFUL124B02_RS39595	COG1131	(ABC) transporter
MFUL124B02_RS39605	COG1505	serine-type exopeptidase activity
MFUL124B02_RS39625	COG1858	cytochrome C peroxidase
MFUL124B02_RS39650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MFUL124B02_RS39665	COG0308	aminopeptidase N
MFUL124B02_RS39685	COG1668	transmembrane transport
MFUL124B02_RS39690	COG4555	ABC transporter
MFUL124B02_RS39705	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MFUL124B02_RS39780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MFUL124B02_RS39795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MFUL124B02_RS39795	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MFUL124B02_RS39805	COG1309	transcriptional regulator
MFUL124B02_RS39820	COG0604	alcohol dehydrogenase
MFUL124B02_RS39820	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS39820	COG3321	synthase
MFUL124B02_RS39830	COG4191	Histidine kinase
MFUL124B02_RS39860	COG0546	phosphoglycolate phosphatase activity
MFUL124B02_RS39880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MFUL124B02_RS39885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFUL124B02_RS39885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFUL124B02_RS39900	COG2205	protein histidine kinase activity
MFUL124B02_RS39910	COG4221	oxidoreductase activity
MFUL124B02_RS39925	COG3243	poly(R)-hydroxyalkanoic acid synthase
MFUL124B02_RS39940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MFUL124B02_RS39950	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS39990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MFUL124B02_RS39995	COG0412	Dienelactone hydrolase
MFUL124B02_RS40035	COG1160	GTP binding
MFUL124B02_RS40115	COG0166	Belongs to the GPI family
MFUL124B02_RS40170	COG1271	oxidase subunit
MFUL124B02_RS40195	COG1959	2 iron, 2 sulfur cluster binding
MFUL124B02_RS40200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MFUL124B02_RS40205	COG2346	COG2346, Truncated hemoglobins
MFUL124B02_RS40210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MFUL124B02_RS40215	COG0640	Transcriptional regulator
MFUL124B02_RS40220	COG0640	Transcriptional regulator
MFUL124B02_RS40225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MFUL124B02_RS40235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MFUL124B02_RS40245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MFUL124B02_RS40250	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS40255	COG2949	membrane
MFUL124B02_RS40270	COG3118	belongs to the thioredoxin family
MFUL124B02_RS40340	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS40345	COG0667	Aldo Keto reductase
MFUL124B02_RS40360	COG2226	methyltransferase
MFUL124B02_RS40400	COG1063	alcohol dehydrogenase
MFUL124B02_RS40410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS40415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MFUL124B02_RS40425	COG2226	methyltransferase
MFUL124B02_RS40430	COG0564	pseudouridine synthase activity
MFUL124B02_RS40435	COG0835	chemotaxis
MFUL124B02_RS40440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MFUL124B02_RS40450	COG0840	transmembrane signaling receptor activity
MFUL124B02_RS40460	COG2201	protein-glutamate methylesterase activity
MFUL124B02_RS40465	COG5002	protein histidine kinase activity
MFUL124B02_RS40480	COG2205	protein histidine kinase activity
MFUL124B02_RS40485	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS40500	COG2201	protein-glutamate methylesterase activity
MFUL124B02_RS40520	COG0835	chemotaxis
MFUL124B02_RS40525	COG0643	Histidine kinase
MFUL124B02_RS40525	COG2198	Histidine kinase
MFUL124B02_RS40560	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS40605	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MFUL124B02_RS40650	COG1858	cytochrome C peroxidase
MFUL124B02_RS40670	COG5002	protein histidine kinase activity
MFUL124B02_RS40695	COG0515	serine threonine protein kinase
MFUL124B02_RS40695	COG2815	serine threonine protein kinase
MFUL124B02_RS40700	COG3437	response regulator, receiver
MFUL124B02_RS40785	COG1518	maintenance of DNA repeat elements
MFUL124B02_RS40810	COG1203	CRISPR-associated helicase, Cas3
MFUL124B02_RS40820	COG1012	belongs to the aldehyde dehydrogenase family
MFUL124B02_RS40845	COG0443	Heat shock 70 kDa protein
MFUL124B02_RS40850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFUL124B02_RS40855	COG2205	protein histidine kinase activity
MFUL124B02_RS40915	COG1360	Flagellar Motor Protein
MFUL124B02_RS40970	COG1515	deoxyribonuclease V activity
MFUL124B02_RS41030	COG2270	Major facilitator Superfamily
MFUL124B02_RS41035	COG2423	ornithine cyclodeaminase activity
MFUL124B02_RS41050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFUL124B02_RS41070	COG1472	Belongs to the glycosyl hydrolase 3 family
MFUL124B02_RS41085	COG0217	transcriptional regulatory protein
MFUL124B02_RS41105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MFUL124B02_RS41125	COG0423	glycine-tRNA ligase activity
MFUL124B02_RS41130	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS41130	COG1136	(ABC) transporter
MFUL124B02_RS41155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MFUL124B02_RS41270	COG5640	endopeptidase activity
MFUL124B02_RS41295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MFUL124B02_RS41340	COG0412	Dienelactone hydrolase
MFUL124B02_RS41345	COG0545	Peptidyl-prolyl cis-trans isomerase
MFUL124B02_RS41375	COG1176	ABC-type spermidine putrescine transport system, permease component I
MFUL124B02_RS41380	COG3842	ATPase activity
MFUL124B02_RS41395	COG1228	amidohydrolase
MFUL124B02_RS41400	COG0534	Mate efflux family protein
MFUL124B02_RS41410	COG2205	protein histidine kinase activity
MFUL124B02_RS41410	COG0784	Response regulator, receiver
MFUL124B02_RS41430	COG1058	Belongs to the CinA family
MFUL124B02_RS41430	COG1546	Belongs to the CinA family
MFUL124B02_RS41510	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS41510	COG1136	(ABC) transporter
MFUL124B02_RS41515	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS41515	COG1136	(ABC) transporter
MFUL124B02_RS41525	COG0577	efflux transmembrane transporter activity
MFUL124B02_RS41525	COG1136	(ABC) transporter
MFUL124B02_RS41530	COG1136	(ABC) transporter
MFUL124B02_RS41540	COG0318	PFAM AMP-dependent synthetase and ligase
MFUL124B02_RS41550	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MFUL124B02_RS41565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFUL124B02_RS41570	COG1024	Enoyl-CoA hydratase
MFUL124B02_RS41580	COG1560	Kdo2-lipid A biosynthetic process
MFUL124B02_RS41595	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MFUL124B02_RS41600	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS41620	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS41655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFUL124B02_RS41660	COG3118	belongs to the thioredoxin family
MFUL124B02_RS41685	COG2860	membrane
MFUL124B02_RS41710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MFUL124B02_RS41730	COG1846	Transcriptional regulator
MFUL124B02_RS41755	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS41775	COG2205	protein histidine kinase activity
MFUL124B02_RS41805	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS41810	COG0438	transferase activity, transferring glycosyl groups
MFUL124B02_RS41850	COG1056	cytidyltransferase-related domain
MFUL124B02_RS41850	COG1051	belongs to the nudix hydrolase family
MFUL124B02_RS41865	COG1028	Short-chain dehydrogenase reductase Sdr
MFUL124B02_RS41955	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS41960	COG0604	alcohol dehydrogenase
MFUL124B02_RS41970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFUL124B02_RS41975	COG0798	PFAM Bile acid sodium symporter
MFUL124B02_RS41980	COG0640	Transcriptional regulator
MFUL124B02_RS42105	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MFUL124B02_RS42145	COG1509	lysine 2,3-aminomutase activity
MFUL124B02_RS42215	COG1127	ABC transporter
MFUL124B02_RS42260	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MFUL124B02_RS42290	COG0714	Associated with various cellular activities
MFUL124B02_RS42300	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MFUL124B02_RS42310	COG0596	Alpha beta hydrolase
MFUL124B02_RS42315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MFUL124B02_RS42345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFUL124B02_RS42360	COG2226	methyltransferase
MFUL124B02_RS42365	COG0515	serine threonine protein kinase
MFUL124B02_RS42370	COG3932	Exopolysaccharide synthesis, ExoD
MFUL124B02_RS42380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFUL124B02_RS42470	COG1653	transport
MFUL124B02_RS42500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFUL124B02_RS42520	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MFUL124B02_RS42520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MFUL124B02_RS42600	COG1309	transcriptional regulator
MFUL124B02_RS42640	COG1064	alcohol dehydrogenase
MFUL124B02_RS42650	COG2755	lipolytic protein G-D-S-L family
MFUL124B02_RS42650	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MFUL124B02_RS42670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MFUL124B02_RS42725	COG2900	Belongs to the SlyX family
MFUL124B02_RS42765	COG0242	peptide deformylase activity
MFUL124B02_RS42795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFUL124B02_RS42800	COG3852	Histidine kinase
MFUL124B02_RS42815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFUL124B02_RS42830	COG2204	response regulator
MFUL124B02_RS42835	COG3852	Histidine kinase
MFUL124B02_RS42875	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MFUL124B02_RS42885	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MFUL124B02_RS42910	COG0823	Involved in the tonB-independent uptake of proteins
MFUL124B02_RS42910	COG1506	peptidase
MFUL124B02_RS42915	COG0583	DNA-binding transcription factor activity
MFUL124B02_RS42945	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS42950	COG1396	sequence-specific DNA binding
MFUL124B02_RS42960	COG2815	serine threonine protein kinase
MFUL124B02_RS42960	COG0515	serine threonine protein kinase
MFUL124B02_RS42965	COG0515	serine threonine protein kinase
MFUL124B02_RS42965	COG2815	serine threonine protein kinase
MFUL124B02_RS42990	COG0516	GMP reductase activity
MFUL124B02_RS42990	COG0517	IMP dehydrogenase activity
MFUL124B02_RS43025	COG3850	Histidine kinase
MFUL124B02_RS43025	COG5002	protein histidine kinase activity
MFUL124B02_RS43040	COG2205	protein histidine kinase activity
MFUL124B02_RS43060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MFUL124B02_RS43125	COG3483	tryptophan 2,3-dioxygenase activity
MFUL124B02_RS43150	COG0506	proline dehydrogenase activity
MFUL124B02_RS43165	COG1355	regulation of microtubule-based process
MFUL124B02_RS43180	COG2814	Major facilitator Superfamily
MFUL124B02_RS43195	COG0746	molybdenum cofactor guanylyltransferase activity
MFUL124B02_RS43200	COG0303	'Molybdopterin
MFUL124B02_RS43210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MFUL124B02_RS43230	COG0784	Response regulator, receiver
MFUL124B02_RS43245	COG2304	oxidoreductase activity
MFUL124B02_RS43290	COG5002	protein histidine kinase activity
MFUL124B02_RS43295	COG0297	glycogen (starch) synthase activity
MFUL124B02_RS43305	COG0463	Glycosyl transferase, family 2
MFUL124B02_RS43310	COG1045	serine acetyltransferase
MFUL124B02_RS43350	COG4941	Belongs to the sigma-70 factor family
MFUL124B02_RS43355	COG3795	YCII-related domain
MFUL124B02_RS43360	COG0277	FAD linked oxidase domain protein
MFUL124B02_RS43390	COG2204	response regulator
MFUL124B02_RS43400	COG0515	serine threonine protein kinase
MFUL124B02_RS43400	COG2815	serine threonine protein kinase
MFUL124B02_RS43410	COG2423	ornithine cyclodeaminase activity
MFUL124B02_RS43455	COG0745	RESPONSE REGULATOR receiver
MFUL124B02_RS43460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MFUL124B02_RS43465	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MFUL124B02_RS43475	COG1832	CoA-binding protein
MFUL124B02_RS43490	COG1475	DNA binding
MFUL124B02_RS43495	COG1192	Involved in chromosome partitioning
MFUL124B02_RS43515	COG0357	Ribosomal RNA small subunit methyltransferase G
MFUL124B02_RS43520	COG0445	tRNA wobble uridine modification
MFUL124B02_RS43525	COG2814	Major facilitator Superfamily
MFUL124B02_RS43535	COG0612	Peptidase, M16
MFUL124B02_RS43560	COG0667	Aldo Keto reductase
MFUL124B02_RS43565	COG0616	signal peptide processing
MFUL124B02_RS43580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MFUL124B02_RS43600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MFUL124B02_RS43605	COG0594	ribonuclease P activity
MFUL124B02_RS43610	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MFUL124B02_RS43715	COG2205	protein histidine kinase activity
MFUL124B02_RS43725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFUL124B02_RS43745	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MFUL124B02_RS43840	COG2264	protein methyltransferase activity
MFUL124B02_RS43870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFUL124B02_RS43890	COG1309	transcriptional regulator
MFUL124B02_RS43895	COG2815	serine threonine protein kinase
MFUL124B02_RS43895	COG0515	serine threonine protein kinase
MFUL124B02_RS43900	COG4978	Transcriptional regulator
MFUL124B02_RS43900	COG0789	Transcriptional regulator
MFUL124B02_RS43995	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MFUL124B02_RS44115	COG0515	serine threonine protein kinase
MFUL124B02_RS44120	COG0750	zinc metalloprotease
MFUL124B02_RS44140	COG1716	ATPase activity
MFUL124B02_RS44150	COG4191	Histidine kinase
MFUL124B02_RS44175	COG0456	acetyltransferase
MFUL124B02_RS44210	COG0751	glycine-tRNA ligase activity
MFUL124B02_RS44215	COG0751	glycine-tRNA ligase activity
MFUL124B02_RS44245	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MFUL124B02_RS44285	COG3275	phosphorelay sensor kinase activity
MFUL124B02_RS44305	COG0515	serine threonine protein kinase
MFUL124B02_RS44390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MFUL124B02_RS44585	COG3344	reverse transcriptase
MFUL124B02_RS44590	COG0515	serine threonine protein kinase
MFUL124B02_RS44600	COG2205	protein histidine kinase activity
MFUL124B02_RS44615	COG2602	Beta-lactamase
MFUL124B02_RS44670	COG2815	serine threonine protein kinase
MFUL124B02_RS44670	COG0515	serine threonine protein kinase
MFUL124B02_RS44685	COG2815	serine threonine protein kinase
MFUL124B02_RS44685	COG0515	serine threonine protein kinase
MFUL124B02_RS44695	COG3854	ATPases associated with a variety of cellular activities
MFUL124B02_RS44750	COG0784	Response regulator, receiver
MFUL124B02_RS44750	COG2205	protein histidine kinase activity
MFUL124B02_RS44785	COG2815	serine threonine protein kinase
MFUL124B02_RS44785	COG0515	serine threonine protein kinase
MFUL124B02_RS44795	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP