locus-tag	class	description
JKA73_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JKA73_RS00015	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JKA73_RS00045	COG2814	Major facilitator Superfamily
JKA73_RS00055	COG2259	Doxx family
JKA73_RS00065	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JKA73_RS00070	COG3550	peptidyl-serine autophosphorylation
JKA73_RS00080	COG0189	ligase activity
JKA73_RS00085	COG0515	serine threonine protein kinase
JKA73_RS00125	COG0557	exoribonuclease II activity
JKA73_RS00190	COG3387	PFAM Glycoside hydrolase 15-related
JKA73_RS00265	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JKA73_RS00295	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JKA73_RS00305	COG1690	Belongs to the RtcB family
JKA73_RS00330	COG2815	serine threonine protein kinase
JKA73_RS00330	COG0515	serine threonine protein kinase
JKA73_RS00355	COG0402	S-adenosylhomocysteine deaminase activity
JKA73_RS00370	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JKA73_RS00380	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS00395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JKA73_RS00405	COG2814	Major facilitator Superfamily
JKA73_RS00410	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
JKA73_RS00415	COG0625	glutathione transferase activity
JKA73_RS00450	COG4106	trans-aconitate 2-methyltransferase activity
JKA73_RS00455	COG3550	peptidyl-serine autophosphorylation
JKA73_RS00485	COG3173	Aminoglycoside phosphotransferase
JKA73_RS00490	COG0477	Major facilitator Superfamily
JKA73_RS00500	COG0577	efflux transmembrane transporter activity
JKA73_RS00500	COG1136	(ABC) transporter
JKA73_RS00505	COG0577	efflux transmembrane transporter activity
JKA73_RS00550	COG2204	response regulator
JKA73_RS00555	COG0515	serine threonine protein kinase
JKA73_RS00580	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
JKA73_RS00580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKA73_RS00590	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JKA73_RS00600	COG2843	Capsule synthesis protein
JKA73_RS00620	COG0038	chloride channel
JKA73_RS00640	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JKA73_RS00650	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JKA73_RS00655	COG1073	alpha beta
JKA73_RS00700	COG4717	serine-type aminopeptidase activity
JKA73_RS00705	COG0420	3'-5' exonuclease activity
JKA73_RS00725	COG5000	phosphorelay sensor kinase activity
JKA73_RS00735	COG5006	permease, DMT superfamily
JKA73_RS00760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JKA73_RS00780	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JKA73_RS00790	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JKA73_RS00795	COG2205	protein histidine kinase activity
JKA73_RS00800	COG5002	protein histidine kinase activity
JKA73_RS00830	COG0840	transmembrane signaling receptor activity
JKA73_RS00835	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JKA73_RS00850	COG2205	protein histidine kinase activity
JKA73_RS00860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JKA73_RS00865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKA73_RS00870	COG2204	response regulator
JKA73_RS00875	COG0446	pyridine nucleotide-disulphide oxidoreductase
JKA73_RS00930	COG2304	oxidoreductase activity
JKA73_RS00940	COG4999	Histidine kinase
JKA73_RS00940	COG3850	Histidine kinase
JKA73_RS00940	COG3437	response regulator, receiver
JKA73_RS00940	COG2205	protein histidine kinase activity
JKA73_RS00945	COG5002	protein histidine kinase activity
JKA73_RS00950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JKA73_RS00955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JKA73_RS00960	COG0697	spore germination
JKA73_RS00970	COG1233	COG1233 Phytoene dehydrogenase and related
JKA73_RS00980	COG2226	methyltransferase
JKA73_RS00985	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JKA73_RS00990	COG1404	Belongs to the peptidase S8 family
JKA73_RS01010	COG1196	nuclear chromosome segregation
JKA73_RS01010	COG0741	lytic transglycosylase activity
JKA73_RS01010	COG0739	heme binding
JKA73_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS01020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JKA73_RS01025	COG1522	sequence-specific DNA binding
JKA73_RS01030	COG1309	transcriptional regulator
JKA73_RS01035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JKA73_RS01100	COG0840	transmembrane signaling receptor activity
JKA73_RS01110	COG5002	protein histidine kinase activity
JKA73_RS01175	COG4335	DNA alkylation repair
JKA73_RS01180	COG2205	protein histidine kinase activity
JKA73_RS01180	COG0784	Response regulator, receiver
JKA73_RS01185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JKA73_RS01200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JKA73_RS01205	COG1127	ABC transporter
JKA73_RS01230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JKA73_RS01245	COG0745	RESPONSE REGULATOR receiver
JKA73_RS01250	COG0475	glutathione-regulated potassium exporter activity
JKA73_RS01255	COG1396	sequence-specific DNA binding
JKA73_RS01335	COG1051	belongs to the nudix hydrolase family
JKA73_RS01340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JKA73_RS01345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JKA73_RS01350	COG1690	Belongs to the RtcB family
JKA73_RS01380	COG2181	nitrate reductase activity
JKA73_RS01380	COG0247	lactate metabolic process
JKA73_RS01410	COG0477	Major facilitator Superfamily
JKA73_RS01425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKA73_RS01430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKA73_RS01460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JKA73_RS01465	COG0667	Aldo Keto reductase
JKA73_RS01530	COG4948	Mandelate Racemase Muconate Lactonizing
JKA73_RS01585	COG0586	Pfam SNARE associated Golgi protein
JKA73_RS01620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKA73_RS01635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JKA73_RS01635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JKA73_RS01640	COG0745	RESPONSE REGULATOR receiver
JKA73_RS01660	COG0784	Response regulator, receiver
JKA73_RS01660	COG2205	protein histidine kinase activity
JKA73_RS01665	COG3158	transport of potassium into the cell
JKA73_RS01690	COG0823	Involved in the tonB-independent uptake of proteins
JKA73_RS01720	COG0189	ligase activity
JKA73_RS01725	COG2204	response regulator
JKA73_RS01755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JKA73_RS01805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JKA73_RS01810	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JKA73_RS01815	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JKA73_RS01850	COG2239	Acts as a magnesium transporter
JKA73_RS01895	COG0582	viral genome integration into host DNA
JKA73_RS01925	COG0515	serine threonine protein kinase
JKA73_RS01925	COG2815	serine threonine protein kinase
JKA73_RS01955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JKA73_RS01975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JKA73_RS01980	COG0515	serine threonine protein kinase
JKA73_RS01985	COG4191	Histidine kinase
JKA73_RS01990	COG1881	PFAM PEBP family protein
JKA73_RS02005	COG0356	it plays a direct role in the translocation of protons across the membrane
JKA73_RS02010	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JKA73_RS02015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JKA73_RS02020	COG0012	GTP binding
JKA73_RS02030	COG0372	Belongs to the citrate synthase family
JKA73_RS02035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JKA73_RS02065	COG1408	metallophosphoesterase
JKA73_RS02105	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS02170	COG2258	MOSC domain
JKA73_RS02280	COG4191	Histidine kinase
JKA73_RS02285	COG2204	response regulator
JKA73_RS02290	COG3852	Histidine kinase
JKA73_RS02300	COG0006	proline dipeptidase activity
JKA73_RS02320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JKA73_RS02325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JKA73_RS02330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JKA73_RS02370	COG0602	queuosine metabolic process
JKA73_RS02375	COG2816	NAD+ diphosphatase activity
JKA73_RS02380	COG0346	lactoylglutathione lyase activity
JKA73_RS02395	COG2070	2-Nitropropane dioxygenase
JKA73_RS02490	COG2826	transposase and inactivated derivatives, IS30 family
JKA73_RS02500	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JKA73_RS02530	COG4771	TonB-dependent receptor
JKA73_RS02540	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JKA73_RS02540	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JKA73_RS02565	COG2815	serine threonine protein kinase
JKA73_RS02565	COG0515	serine threonine protein kinase
JKA73_RS02600	COG0436	Aminotransferase
JKA73_RS02620	COG0551	DNA topoisomerase type I activity
JKA73_RS02620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JKA73_RS02630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JKA73_RS02645	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JKA73_RS02650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JKA73_RS02685	COG0625	glutathione transferase activity
JKA73_RS02705	COG0515	serine threonine protein kinase
JKA73_RS02710	COG0842	Transport permease protein
JKA73_RS02715	COG1131	(ABC) transporter
JKA73_RS02735	COG0488	(ABC) transporter
JKA73_RS02740	COG1876	peptidase activity
JKA73_RS02745	COG0501	Belongs to the peptidase M48B family
JKA73_RS02790	COG1525	nuclease
JKA73_RS02795	COG5002	protein histidine kinase activity
JKA73_RS02875	COG1819	glycosyl
JKA73_RS02880	COG0668	transmembrane transport
JKA73_RS02895	COG0517	IMP dehydrogenase activity
JKA73_RS02895	COG1125	glycine betaine transport
JKA73_RS02910	COG0109	protoheme IX farnesyltransferase activity
JKA73_RS02910	COG1612	heme a metabolic process
JKA73_RS02915	COG2204	response regulator
JKA73_RS02945	COG0671	phosphoesterase, PA-phosphatase related
JKA73_RS02955	COG0110	maltose O-acetyltransferase activity
JKA73_RS02960	COG4191	Histidine kinase
JKA73_RS02975	COG1793	dna ligase
JKA73_RS02980	COG3265	gluconokinase activity
JKA73_RS02990	COG2376	Dihydroxyacetone kinase
JKA73_RS03010	COG0488	(ABC) transporter
JKA73_RS03070	COG1309	transcriptional regulator
JKA73_RS03080	COG1116	anion transmembrane transporter activity
JKA73_RS03110	COG1192	Involved in chromosome partitioning
JKA73_RS03120	COG0501	Belongs to the peptidase M48B family
JKA73_RS03130	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JKA73_RS03160	COG5002	protein histidine kinase activity
JKA73_RS03165	COG0308	aminopeptidase N
JKA73_RS03200	COG1846	Transcriptional regulator
JKA73_RS03205	COG1764	response to oxidative stress
JKA73_RS03230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JKA73_RS03250	COG1234	tRNA 3'-trailer cleavage
JKA73_RS03260	COG1309	transcriptional regulator
JKA73_RS03265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JKA73_RS03295	COG1278	Cold shock
JKA73_RS03325	COG0667	Aldo Keto reductase
JKA73_RS03335	COG3795	YCII-related domain
JKA73_RS03340	COG4941	Belongs to the sigma-70 factor family
JKA73_RS03350	COG2124	cytochrome p450
JKA73_RS03355	COG4604	ABC transporter, ATP-binding protein
JKA73_RS03360	COG4605	iron ion homeostasis
JKA73_RS03365	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKA73_RS03370	COG4607	ABC-type enterochelin transport system periplasmic component
JKA73_RS03400	COG0577	efflux transmembrane transporter activity
JKA73_RS03400	COG1136	(ABC) transporter
JKA73_RS03440	COG2031	fatty acid transporter
JKA73_RS03450	COG5002	protein histidine kinase activity
JKA73_RS03465	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JKA73_RS03470	COG0745	RESPONSE REGULATOR receiver
JKA73_RS03480	COG4999	Histidine kinase
JKA73_RS03480	COG2205	protein histidine kinase activity
JKA73_RS03480	COG3850	Histidine kinase
JKA73_RS03480	COG3437	response regulator, receiver
JKA73_RS03485	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JKA73_RS03490	COG2201	protein-glutamate methylesterase activity
JKA73_RS03495	COG3437	response regulator, receiver
JKA73_RS03520	COG1131	(ABC) transporter
JKA73_RS03540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JKA73_RS03545	COG0745	RESPONSE REGULATOR receiver
JKA73_RS03565	COG3483	tryptophan 2,3-dioxygenase activity
JKA73_RS03570	COG0745	RESPONSE REGULATOR receiver
JKA73_RS03575	COG3850	Histidine kinase
JKA73_RS03575	COG3437	response regulator, receiver
JKA73_RS03575	COG4999	Histidine kinase
JKA73_RS03575	COG2205	protein histidine kinase activity
JKA73_RS03595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKA73_RS03645	COG1132	(ABC) transporter
JKA73_RS03655	COG0484	heat shock protein binding
JKA73_RS03700	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JKA73_RS03755	COG0745	RESPONSE REGULATOR receiver
JKA73_RS03780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JKA73_RS03800	COG3842	ATPase activity
JKA73_RS03810	COG0300	oxidoreductase activity
JKA73_RS03835	COG0330	HflC and HflK could
JKA73_RS03845	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS03860	COG0583	DNA-binding transcription factor activity
JKA73_RS03875	COG0537	adenosine 5'-monophosphoramidase activity
JKA73_RS03890	COG0612	Peptidase, M16
JKA73_RS03920	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS03965	COG0679	Auxin Efflux Carrier
JKA73_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS04105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JKA73_RS04140	COG0604	alcohol dehydrogenase
JKA73_RS04150	COG3383	formate dehydrogenase (NAD+) activity
JKA73_RS04160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JKA73_RS04170	COG1360	Flagellar Motor Protein
JKA73_RS04185	COG0443	Heat shock 70 kDa protein
JKA73_RS04205	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JKA73_RS04210	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JKA73_RS04215	COG0625	glutathione transferase activity
JKA73_RS04225	COG0783	Belongs to the Dps family
JKA73_RS04310	COG2819	hydrolase of the alpha beta superfamily
JKA73_RS04325	COG1309	transcriptional regulator
JKA73_RS04330	COG1408	metallophosphoesterase
JKA73_RS04355	COG1090	epimerase
JKA73_RS04365	COG0142	geranyltranstransferase activity
JKA73_RS04375	COG1562	ergosterol biosynthetic process
JKA73_RS04380	COG1233	COG1233 Phytoene dehydrogenase and related
JKA73_RS04425	COG2815	serine threonine protein kinase
JKA73_RS04425	COG0515	serine threonine protein kinase
JKA73_RS04430	COG2204	response regulator
JKA73_RS04455	COG0174	glutamine synthetase
JKA73_RS04470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JKA73_RS04475	COG3844	kynureninase activity
JKA73_RS04485	COG0662	Cupin 2, conserved barrel domain protein
JKA73_RS04530	COG4191	Histidine kinase
JKA73_RS04550	COG1297	OPT oligopeptide transporter protein
JKA73_RS04555	COG2815	serine threonine protein kinase
JKA73_RS04555	COG0515	serine threonine protein kinase
JKA73_RS04560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKA73_RS04575	COG2204	response regulator
JKA73_RS04605	COG1846	Transcriptional regulator
JKA73_RS04640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JKA73_RS04650	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JKA73_RS04655	COG0363	glucosamine-6-phosphate deaminase activity
JKA73_RS04660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JKA73_RS04690	COG0420	3'-5' exonuclease activity
JKA73_RS04725	COG1464	Belongs to the NlpA lipoprotein family
JKA73_RS04730	COG2011	ABC-type metal ion transport system permease component
JKA73_RS04735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JKA73_RS04740	COG0626	cystathionine gamma-synthase activity
JKA73_RS04745	COG0626	cystathionine gamma-synthase activity
JKA73_RS04750	COG0460	homoserine dehydrogenase
JKA73_RS04750	COG0527	aspartate kinase activity
JKA73_RS04765	COG1858	cytochrome C peroxidase
JKA73_RS04800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JKA73_RS04815	COG3023	N-Acetylmuramoyl-L-alanine amidase
JKA73_RS04845	COG2205	protein histidine kinase activity
JKA73_RS04855	COG3842	ATPase activity
JKA73_RS04860	COG0644	oxidoreductase
JKA73_RS04865	COG1201	RNA secondary structure unwinding
JKA73_RS04870	COG1404	Belongs to the peptidase S8 family
JKA73_RS04950	COG5002	protein histidine kinase activity
JKA73_RS04965	COG4968	Prepilin-type N-terminal cleavage methylation domain
JKA73_RS04995	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JKA73_RS05005	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS05010	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS05025	COG0297	glycogen (starch) synthase activity
JKA73_RS05035	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS05060	COG0463	Glycosyl transferase, family 2
JKA73_RS05060	COG1216	Glycosyl transferase, family 2
JKA73_RS05070	COG1940	carbohydrate kinase activity
JKA73_RS05085	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS05090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JKA73_RS05150	COG3724	N-succinylarginine dihydrolase activity
JKA73_RS05155	COG1560	Kdo2-lipid A biosynthetic process
JKA73_RS05170	COG1137	ATPase activity
JKA73_RS05190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JKA73_RS05195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKA73_RS05195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JKA73_RS05195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JKA73_RS05205	COG1490	D-aminoacyl-tRNA deacylase activity
JKA73_RS05210	COG2027	D-alanyl-D-alanine carboxypeptidase
JKA73_RS05215	COG0629	single-stranded DNA binding
JKA73_RS05220	COG2009	succinate dehydrogenase
JKA73_RS05225	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JKA73_RS05235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JKA73_RS05245	COG4191	Histidine kinase
JKA73_RS05250	COG2204	response regulator
JKA73_RS05260	COG1007	ATP synthesis coupled electron transport
JKA73_RS05275	COG0713	ATP synthesis coupled electron transport
JKA73_RS05280	COG0839	Belongs to the complex I subunit 6 family
JKA73_RS05305	COG0560	Phosphoserine phosphatase
JKA73_RS05305	COG3830	Belongs to the UPF0237 family
JKA73_RS05320	COG0071	Belongs to the small heat shock protein (HSP20) family
JKA73_RS05325	COG0745	RESPONSE REGULATOR receiver
JKA73_RS05330	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JKA73_RS05335	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JKA73_RS05340	COG0504	CTP synthase activity
JKA73_RS05350	COG1132	(ABC) transporter
JKA73_RS05355	COG0656	L-ascorbic acid biosynthetic process
JKA73_RS05365	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JKA73_RS05375	COG0564	pseudouridine synthase activity
JKA73_RS05380	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JKA73_RS05395	COG0484	heat shock protein binding
JKA73_RS05415	COG0511	ligase activity, forming carbon-carbon bonds
JKA73_RS05415	COG5016	pyruvate
JKA73_RS05420	COG0439	Biotin carboxylase
JKA73_RS05430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JKA73_RS05485	COG2264	protein methyltransferase activity
JKA73_RS05495	COG2264	protein methyltransferase activity
JKA73_RS05510	COG2204	response regulator
JKA73_RS05515	COG4191	Histidine kinase
JKA73_RS05525	COG1714	RDD family
JKA73_RS05540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JKA73_RS05570	COG2264	protein methyltransferase activity
JKA73_RS05580	COG0612	Peptidase, M16
JKA73_RS05635	COG1959	2 iron, 2 sulfur cluster binding
JKA73_RS05640	COG0719	Fe-S assembly protein
JKA73_RS05645	COG0396	ATPase activity
JKA73_RS05650	COG0719	Fe-S assembly protein
JKA73_RS05660	COG0822	iron-sulfur transferase activity
JKA73_RS05675	COG1446	asparaginase
JKA73_RS05690	COG0515	serine threonine protein kinase
JKA73_RS05690	COG2815	serine threonine protein kinase
JKA73_RS05710	COG2205	protein histidine kinase activity
JKA73_RS05715	COG2204	response regulator
JKA73_RS05735	COG1376	ErfK ybiS ycfS ynhG family protein
JKA73_RS05740	COG0432	Pfam Uncharacterised protein family UPF0047
JKA73_RS05760	COG0544	peptidyl-prolyl cis-trans isomerase activity
JKA73_RS05770	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JKA73_RS05790	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JKA73_RS05825	COG5000	phosphorelay sensor kinase activity
JKA73_RS05870	COG1040	competence protein
JKA73_RS05875	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JKA73_RS05885	COG1690	Belongs to the RtcB family
JKA73_RS05890	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JKA73_RS05940	COG3852	Histidine kinase
JKA73_RS05945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JKA73_RS05950	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JKA73_RS05960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JKA73_RS05965	COG0156	8-amino-7-oxononanoate synthase activity
JKA73_RS05970	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JKA73_RS05995	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JKA73_RS06000	COG3273	potassium ion transport
JKA73_RS06000	COG0471	metal ion transport
JKA73_RS06030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JKA73_RS06050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JKA73_RS06070	COG3279	Response regulator of the LytR AlgR family
JKA73_RS06075	COG3275	phosphorelay sensor kinase activity
JKA73_RS06095	COG0297	glycogen (starch) synthase activity
JKA73_RS06120	COG4535	Mg2 and Co2 transporter CorC
JKA73_RS06145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JKA73_RS06165	COG4771	TonB-dependent receptor
JKA73_RS06175	COG3720	iron ion transport
JKA73_RS06185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKA73_RS06190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JKA73_RS06305	COG3604	Transcriptional regulator
JKA73_RS06390	COG0745	RESPONSE REGULATOR receiver
JKA73_RS06395	COG5002	protein histidine kinase activity
JKA73_RS06415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JKA73_RS06430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JKA73_RS06455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JKA73_RS06460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JKA73_RS06465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JKA73_RS06500	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JKA73_RS06510	COG0123	including yeast histone deacetylase and acetoin utilization protein
JKA73_RS06565	COG0405	Gamma-glutamyltransferase
JKA73_RS06575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JKA73_RS06580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JKA73_RS06605	COG2183	response to ionizing radiation
JKA73_RS06620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JKA73_RS06635	COG1413	lyase activity
JKA73_RS06645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JKA73_RS06650	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JKA73_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS06715	COG0840	transmembrane signaling receptor activity
JKA73_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS06750	COG0564	pseudouridine synthase activity
JKA73_RS06755	COG1215	transferase activity, transferring glycosyl groups
JKA73_RS06770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JKA73_RS06785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JKA73_RS06790	COG0484	heat shock protein binding
JKA73_RS06795	COG0242	peptide deformylase activity
JKA73_RS06800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JKA73_RS06810	COG0739	heme binding
JKA73_RS06815	COG0776	regulation of translation
JKA73_RS06830	COG1183	phosphatidylcholine synthase activity
JKA73_RS06835	COG1058	Belongs to the CinA family
JKA73_RS06835	COG1546	Belongs to the CinA family
JKA73_RS06855	COG1252	NADH dehydrogenase
JKA73_RS06860	COG0606	chelatase, subunit chli
JKA73_RS06930	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JKA73_RS06935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JKA73_RS06935	COG0116	Belongs to the methyltransferase superfamily
JKA73_RS06955	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JKA73_RS06960	COG0154	amidase activity
JKA73_RS06965	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JKA73_RS06990	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JKA73_RS06995	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JKA73_RS07000	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JKA73_RS07025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JKA73_RS07035	COG1666	GTP binding
JKA73_RS07040	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JKA73_RS07045	COG0515	serine threonine protein kinase
JKA73_RS07120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JKA73_RS07160	COG1515	deoxyribonuclease V activity
JKA73_RS07190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JKA73_RS07225	COG0210	DNA helicase
JKA73_RS07240	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JKA73_RS07250	COG1690	Belongs to the RtcB family
JKA73_RS07265	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JKA73_RS07280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JKA73_RS07285	COG0318	PFAM AMP-dependent synthetase and ligase
JKA73_RS07325	COG2967	ApaG domain
JKA73_RS07345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKA73_RS07355	COG0009	L-threonylcarbamoyladenylate synthase
JKA73_RS07360	COG1090	epimerase
JKA73_RS07395	COG2202	Pas domain
JKA73_RS07395	COG2205	protein histidine kinase activity
JKA73_RS07405	COG0723	plastoquinol--plastocyanin reductase activity
JKA73_RS07405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JKA73_RS07425	COG2814	Major facilitator Superfamily
JKA73_RS07430	COG0531	amino acid
JKA73_RS07435	COG2264	protein methyltransferase activity
JKA73_RS07460	COG0450	alkyl hydroperoxide reductase
JKA73_RS07465	COG3604	Transcriptional regulator
JKA73_RS07480	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JKA73_RS07490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JKA73_RS07500	COG1045	serine acetyltransferase
JKA73_RS07505	COG0318	PFAM AMP-dependent synthetase and ligase
JKA73_RS07510	COG3070	regulator of competence-specific genes
JKA73_RS07515	COG0583	DNA-binding transcription factor activity
JKA73_RS07520	COG0477	Major facilitator Superfamily
JKA73_RS07525	COG2815	serine threonine protein kinase
JKA73_RS07525	COG0515	serine threonine protein kinase
JKA73_RS07535	COG1238	metal cluster binding
JKA73_RS07545	COG0628	permease
JKA73_RS07570	COG1187	pseudouridine synthase activity
JKA73_RS07585	COG0512	Glutamine amidotransferase of anthranilate synthase
JKA73_RS07635	COG2264	protein methyltransferase activity
JKA73_RS07640	COG0436	Aminotransferase
JKA73_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS07655	COG0318	PFAM AMP-dependent synthetase and ligase
JKA73_RS07655	COG0300	oxidoreductase activity
JKA73_RS07655	COG3321	synthase
JKA73_RS07655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JKA73_RS07695	COG2010	Cytochrome c
JKA73_RS07725	COG1278	Cold shock
JKA73_RS07735	COG2378	regulation of single-species biofilm formation
JKA73_RS07805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKA73_RS07815	COG0531	amino acid
JKA73_RS07845	COG0673	inositol 2-dehydrogenase activity
JKA73_RS07850	COG1132	(ABC) transporter
JKA73_RS07855	COG1088	dTDP-glucose 4,6-dehydratase activity
JKA73_RS07860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JKA73_RS07865	COG0297	glycogen (starch) synthase activity
JKA73_RS07905	COG1959	2 iron, 2 sulfur cluster binding
JKA73_RS07910	COG2267	carboxylic ester hydrolase activity
JKA73_RS07920	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JKA73_RS07935	COG2272	Belongs to the type-B carboxylesterase lipase family
JKA73_RS08000	COG2814	Major facilitator Superfamily
JKA73_RS08060	COG2937	Belongs to the GPAT DAPAT family
JKA73_RS08065	COG0277	FAD linked oxidase domain protein
JKA73_RS08070	COG1309	transcriptional regulator
JKA73_RS08080	COG0642	Histidine kinase
JKA73_RS08095	COG0823	Involved in the tonB-independent uptake of proteins
JKA73_RS08095	COG1506	peptidase
JKA73_RS08100	COG0583	DNA-binding transcription factor activity
JKA73_RS08115	COG0456	acetyltransferase
JKA73_RS08120	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JKA73_RS08150	COG0577	efflux transmembrane transporter activity
JKA73_RS08150	COG1136	(ABC) transporter
JKA73_RS08225	COG0515	serine threonine protein kinase
JKA73_RS08310	COG3811	Belongs to the UPF0386 family
JKA73_RS08370	COG0753	catalase activity
JKA73_RS08380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JKA73_RS08425	COG0667	Aldo Keto reductase
JKA73_RS08430	COG0583	DNA-binding transcription factor activity
JKA73_RS08445	COG1846	Transcriptional regulator
JKA73_RS08470	COG1404	Belongs to the peptidase S8 family
JKA73_RS08805	COG4653	Phage capsid family
JKA73_RS08815	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JKA73_RS08835	COG5518	Phage portal protein
JKA73_RS08845	COG2205	protein histidine kinase activity
JKA73_RS08875	COG2176	DNA-directed DNA polymerase activity
JKA73_RS08950	COG2815	serine threonine protein kinase
JKA73_RS08950	COG0515	serine threonine protein kinase
JKA73_RS08980	COG0515	serine threonine protein kinase
JKA73_RS09010	COG0737	Belongs to the 5'-nucleotidase family
JKA73_RS09010	COG1525	nuclease
JKA73_RS09010	COG4085	toxin activity
JKA73_RS09030	COG1484	DNA-dependent DNA replication
JKA73_RS09045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JKA73_RS09045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JKA73_RS09050	COG1619	proteins homologs of microcin C7 resistance protein MccF
JKA73_RS09055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JKA73_RS09060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JKA73_RS09065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKA73_RS09070	COG0483	inositol monophosphate 1-phosphatase activity
JKA73_RS09090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS09125	COG1100	Small GTP-binding protein
JKA73_RS09145	COG0515	serine threonine protein kinase
JKA73_RS09150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JKA73_RS09155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JKA73_RS09165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JKA73_RS09190	COG0590	tRNA wobble adenosine to inosine editing
JKA73_RS09210	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JKA73_RS09240	COG1088	dTDP-glucose 4,6-dehydratase activity
JKA73_RS09255	COG0514	ATP-dependent DNA helicase (RecQ)
JKA73_RS09265	COG2003	Belongs to the UPF0758 family
JKA73_RS09270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS09275	COG0492	ferredoxin-NADP+ reductase activity
JKA73_RS09320	COG1832	CoA-binding protein
JKA73_RS09340	COG2226	methyltransferase
JKA73_RS09345	COG0646	methionine synthase
JKA73_RS09345	COG1410	methionine synthase
JKA73_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS09385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JKA73_RS09420	COG0424	maF-like protein
JKA73_RS09445	COG0210	DNA helicase
JKA73_RS09450	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JKA73_RS09470	COG2137	regulation of response to DNA damage stimulus
JKA73_RS09495	COG0709	Synthesizes selenophosphate from selenide and ATP
JKA73_RS09500	COG0860	N-Acetylmuramoyl-L-alanine amidase
JKA73_RS09505	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JKA73_RS09510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JKA73_RS09550	COG0544	peptidyl-prolyl cis-trans isomerase activity
JKA73_RS09555	COG0740	serine-type endopeptidase activity
JKA73_RS09565	COG1505	serine-type exopeptidase activity
JKA73_RS09575	COG4166	transmembrane transport
JKA73_RS09595	COG1678	Uncharacterized ACR, COG1678
JKA73_RS09600	COG0271	Belongs to the BolA IbaG family
JKA73_RS09605	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JKA73_RS09615	COG0006	proline dipeptidase activity
JKA73_RS09625	COG3148	PFAM DTW domain containing protein
JKA73_RS09635	COG1595	DNA-templated transcription, initiation
JKA73_RS09650	COG1573	uracil-dna glycosylase
JKA73_RS09660	COG0626	cystathionine gamma-synthase activity
JKA73_RS09680	COG2030	dehydratase
JKA73_RS09695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JKA73_RS09700	COG0631	protein serine/threonine phosphatase activity
JKA73_RS09710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JKA73_RS09725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JKA73_RS09730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JKA73_RS09740	COG1428	Deoxynucleoside kinase
JKA73_RS09745	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JKA73_RS09750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JKA73_RS09755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JKA73_RS09775	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JKA73_RS09795	COG0779	Required for maturation of 30S ribosomal subunits
JKA73_RS09810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JKA73_RS09820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JKA73_RS09825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JKA73_RS09830	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JKA73_RS09835	COG1185	polyribonucleotide nucleotidyltransferase activity
JKA73_RS09845	COG0739	heme binding
JKA73_RS09850	COG0756	dUTP diphosphatase activity
JKA73_RS09865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JKA73_RS09890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKA73_RS09905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKA73_RS09925	COG0612	Peptidase, M16
JKA73_RS10035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKA73_RS10060	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JKA73_RS10080	COG2390	Transcriptional regulator
JKA73_RS10080	COG4584	PFAM Integrase catalytic
JKA73_RS10185	COG0667	Aldo Keto reductase
JKA73_RS10200	COG2356	endonuclease I
JKA73_RS10230	COG1643	Atp-dependent helicase
JKA73_RS10305	COG1250	3-hydroxyacyl-CoA dehydrogenase
JKA73_RS10330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JKA73_RS10345	COG2133	pyrroloquinoline quinone binding
JKA73_RS10395	COG0657	acetylesterase activity
JKA73_RS10435	COG1268	BioY protein
JKA73_RS10460	COG2814	Major facilitator Superfamily
JKA73_RS10510	COG0194	GDP metabolic process
JKA73_RS10545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JKA73_RS10585	COG3226	Transcriptional regulator
JKA73_RS10595	COG0737	Belongs to the 5'-nucleotidase family
JKA73_RS10600	COG1335	isochorismatase
JKA73_RS10625	COG2226	methyltransferase
JKA73_RS10635	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JKA73_RS10640	COG0277	FAD linked oxidase domain protein
JKA73_RS10670	COG4176	ABC-type proline glycine betaine transport system permease component
JKA73_RS10675	COG2113	Glycine betaine
JKA73_RS10680	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JKA73_RS10700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKA73_RS10710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKA73_RS10720	COG4651	solute:proton antiporter activity
JKA73_RS10720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JKA73_RS10725	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JKA73_RS10725	COG1703	isobutyryl-CoA mutase activity
JKA73_RS10725	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JKA73_RS10730	COG1703	isobutyryl-CoA mutase activity
JKA73_RS10745	COG0328	RNA-DNA hybrid ribonuclease activity
JKA73_RS10750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JKA73_RS10755	COG2070	2-Nitropropane dioxygenase
JKA73_RS10760	COG1136	(ABC) transporter
JKA73_RS10760	COG0577	efflux transmembrane transporter activity
JKA73_RS10945	COG0758	DNA mediated transformation
JKA73_RS11155	COG0306	phosphate transporter
JKA73_RS11165	COG1064	alcohol dehydrogenase
JKA73_RS11170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JKA73_RS11180	COG0427	acetyl-CoA hydrolase
JKA73_RS11185	COG0339	signal peptide processing
JKA73_RS11190	COG0351	phosphomethylpyrimidine kinase
JKA73_RS11200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JKA73_RS11230	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JKA73_RS11245	COG0017	Asparaginyl-tRNA synthetase
JKA73_RS11270	COG2124	cytochrome p450
JKA73_RS11280	COG0813	purine-nucleoside phosphorylase activity
JKA73_RS11295	COG0513	Belongs to the DEAD box helicase family
JKA73_RS11320	COG1063	alcohol dehydrogenase
JKA73_RS11335	COG3850	Histidine kinase
JKA73_RS11335	COG2205	protein histidine kinase activity
JKA73_RS11335	COG3437	response regulator, receiver
JKA73_RS11335	COG4999	Histidine kinase
JKA73_RS11350	COG3541	Predicted nucleotidyltransferase
JKA73_RS11370	COG3228	Belongs to the MtfA family
JKA73_RS11375	COG1072	(Pantothenic acid kinase))
JKA73_RS11390	COG2153	protein acetylation
JKA73_RS11400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JKA73_RS11415	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JKA73_RS11420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JKA73_RS11430	COG0175	sulfate reduction
JKA73_RS11435	COG1648	precorrin-2 dehydrogenase activity
JKA73_RS11435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JKA73_RS11440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JKA73_RS11440	COG1648	precorrin-2 dehydrogenase activity
JKA73_RS11445	COG0175	sulfate reduction
JKA73_RS11480	COG0047	phosphoribosylformylglycinamidine synthase activity
JKA73_RS11480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JKA73_RS11485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JKA73_RS11490	COG0517	IMP dehydrogenase activity
JKA73_RS11495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JKA73_RS11525	COG0019	diaminopimelate decarboxylase activity
JKA73_RS11530	COG1215	transferase activity, transferring glycosyl groups
JKA73_RS11535	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JKA73_RS11545	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS11550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JKA73_RS11575	COG5002	protein histidine kinase activity
JKA73_RS11580	COG1218	3'(2'),5'-bisphosphate nucleotidase
JKA73_RS11590	COG3663	DNA glycosylase
JKA73_RS11605	COG4297	protein containing double-stranded beta helix domain
JKA73_RS11610	COG1228	amidohydrolase
JKA73_RS11620	COG2363	Small membrane protein
JKA73_RS11650	COG2943	transferase activity, transferring hexosyl groups
JKA73_RS11660	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JKA73_RS11675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JKA73_RS11680	COG0386	Belongs to the glutathione peroxidase family
JKA73_RS11730	COG4991	sh3 domain protein
JKA73_RS11730	COG3064	Membrane
JKA73_RS11730	COG0515	serine threonine protein kinase
JKA73_RS11750	COG1301	dicarboxylic acid transport
JKA73_RS11755	COG1047	Peptidyl-prolyl cis-trans
JKA73_RS11770	COG0488	(ABC) transporter
JKA73_RS11775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JKA73_RS11805	COG1187	pseudouridine synthase activity
JKA73_RS11830	COG2373	Large extracellular alpha-helical protein
JKA73_RS11835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JKA73_RS11840	COG4953	penicillin-binding protein 1C
JKA73_RS11865	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JKA73_RS11885	COG1136	(ABC) transporter
JKA73_RS11885	COG0577	efflux transmembrane transporter activity
JKA73_RS11895	COG1136	(ABC) transporter
JKA73_RS11930	COG1191	sigma factor activity
JKA73_RS11985	COG1987	bacterial-type flagellum assembly
JKA73_RS11995	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JKA73_RS12000	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JKA73_RS12055	COG4789	Type iii secretion
JKA73_RS12060	COG1716	ATPase activity
JKA73_RS12105	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JKA73_RS12115	COG0714	Associated with various cellular activities
JKA73_RS12140	COG0616	signal peptide processing
JKA73_RS12155	COG0187	DNA topoisomerase II activity
JKA73_RS12160	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JKA73_RS12180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKA73_RS12185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKA73_RS12290	COG1459	type II secretion system
JKA73_RS12320	COG0312	modulator of DNA gyrase
JKA73_RS12325	COG0312	modulator of DNA gyrase
JKA73_RS12335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS12350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JKA73_RS12380	COG5001	Diguanylate cyclase
JKA73_RS12380	COG3300	MHYT domain
JKA73_RS12395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JKA73_RS12400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JKA73_RS12405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JKA73_RS12410	COG1022	Amp-dependent synthetase and ligase
JKA73_RS12445	COG0416	fatty acid biosynthetic process
JKA73_RS12460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JKA73_RS12470	COG0564	pseudouridine synthase activity
JKA73_RS12505	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JKA73_RS12510	COG4589	Belongs to the CDS family
JKA73_RS12515	COG0750	zinc metalloprotease
JKA73_RS12520	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JKA73_RS12525	COG1214	PFAM Peptidase M22, glycoprotease
JKA73_RS12550	COG0314	molybdopterin synthase activity
JKA73_RS12580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JKA73_RS12585	COG0156	8-amino-7-oxononanoate synthase activity
JKA73_RS12590	COG0406	alpha-ribazole phosphatase activity
JKA73_RS12600	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JKA73_RS12620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JKA73_RS12620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JKA73_RS12660	COG0515	serine threonine protein kinase
JKA73_RS12670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JKA73_RS12690	COG0584	glycerophosphoryl diester phosphodiesterase
JKA73_RS12740	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JKA73_RS12760	COG3104	oligopeptide transport
JKA73_RS12780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JKA73_RS12800	COG0456	acetyltransferase
JKA73_RS12810	COG1074	ATP-dependent DNA helicase activity
JKA73_RS12815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JKA73_RS12855	COG0658	competence protein
JKA73_RS12855	COG2333	competence protein COMEC
JKA73_RS12860	COG1329	Transcriptional regulator
JKA73_RS12875	COG0215	cysteine-tRNA ligase activity
JKA73_RS12885	COG0556	nucleotide-excision repair
JKA73_RS12890	COG0322	excinuclease ABC activity
JKA73_RS12940	COG0424	maF-like protein
JKA73_RS12945	COG3706	GGDEF domain
JKA73_RS12950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JKA73_RS12970	COG0772	Belongs to the SEDS family
JKA73_RS12990	COG3118	belongs to the thioredoxin family
JKA73_RS13005	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JKA73_RS13010	COG0181	hydroxymethylbilane synthase activity
JKA73_RS13015	COG1587	Uroporphyrinogen-III synthase
JKA73_RS13020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JKA73_RS13060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JKA73_RS13065	COG0022	dehydrogenase e1 component
JKA73_RS13070	COG0508	dehydrogenase complex catalyzes the overall conversion of
JKA73_RS13115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JKA73_RS13160	COG0784	Response regulator, receiver
JKA73_RS13210	COG1100	Small GTP-binding protein
JKA73_RS13215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JKA73_RS13225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JKA73_RS13230	COG1024	Enoyl-CoA hydratase
JKA73_RS13235	COG1683	Conserved Protein
JKA73_RS13240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JKA73_RS13245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JKA73_RS13250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS13260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JKA73_RS13265	COG0285	dihydrofolate synthase activity
JKA73_RS13285	COG1396	sequence-specific DNA binding
JKA73_RS13295	COG1309	transcriptional regulator
JKA73_RS13300	COG1024	Enoyl-CoA hydratase
JKA73_RS13355	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JKA73_RS13365	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JKA73_RS13370	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JKA73_RS13375	COG1034	ATP synthesis coupled electron transport
JKA73_RS13380	COG0649	NAD binding
JKA73_RS13385	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JKA73_RS13400	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JKA73_RS13405	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JKA73_RS13430	COG0613	PHP domain protein
JKA73_RS13450	COG1166	arginine decarboxylase activity
JKA73_RS13455	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JKA73_RS13465	COG0484	heat shock protein binding
JKA73_RS13470	COG0443	Heat shock 70 kDa protein
JKA73_RS13515	COG1796	DNA polymerase
JKA73_RS13515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JKA73_RS13525	COG0521	Mo-molybdopterin cofactor biosynthetic process
JKA73_RS13545	COG4191	Histidine kinase
JKA73_RS13620	COG0745	RESPONSE REGULATOR receiver
JKA73_RS13640	COG1136	(ABC) transporter
JKA73_RS13640	COG0577	efflux transmembrane transporter activity
JKA73_RS13660	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JKA73_RS13670	COG0534	Mate efflux family protein
JKA73_RS13700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JKA73_RS13720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS13745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JKA73_RS13745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JKA73_RS13755	COG0084	hydrolase, TatD family'
JKA73_RS13765	COG3481	metal-dependent phosphohydrolase, HD sub domain
JKA73_RS13770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JKA73_RS13780	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JKA73_RS13790	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JKA73_RS13800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JKA73_RS13805	COG0126	phosphoglycerate kinase activity
JKA73_RS13810	COG0149	triose-phosphate isomerase activity
JKA73_RS13845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JKA73_RS13850	COG1116	anion transmembrane transporter activity
JKA73_RS13885	COG1012	belongs to the aldehyde dehydrogenase family
JKA73_RS13890	COG0583	DNA-binding transcription factor activity
JKA73_RS13900	COG1012	belongs to the aldehyde dehydrogenase family
JKA73_RS13910	COG1739	Uncharacterized protein family UPF0029
JKA73_RS13915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JKA73_RS13990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKA73_RS14040	COG1309	transcriptional regulator
JKA73_RS14060	COG2072	flavoprotein involved in K transport
JKA73_RS14075	COG0628	permease
JKA73_RS14110	COG4372	Transposase
JKA73_RS14150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JKA73_RS14195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JKA73_RS14245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JKA73_RS14285	COG2366	antibiotic biosynthetic process
JKA73_RS14290	COG1183	phosphatidylcholine synthase activity
JKA73_RS14305	COG0515	serine threonine protein kinase
JKA73_RS14310	COG0515	serine threonine protein kinase
JKA73_RS14320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JKA73_RS14325	COG0138	bifunctional purine biosynthesis protein purh
JKA73_RS14335	COG0151	Belongs to the GarS family
JKA73_RS14355	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS14365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JKA73_RS14375	COG1215	transferase activity, transferring glycosyl groups
JKA73_RS14380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JKA73_RS14475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JKA73_RS14480	COG1120	ATPase activity
JKA73_RS14510	COG0302	gtp cyclohydrolase
JKA73_RS14515	COG0277	FAD linked oxidase domain protein
JKA73_RS14535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JKA73_RS14545	COG0745	RESPONSE REGULATOR receiver
JKA73_RS14555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JKA73_RS14565	COG1846	Transcriptional regulator
JKA73_RS14580	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS14585	COG1301	dicarboxylic acid transport
JKA73_RS14600	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JKA73_RS14615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JKA73_RS14620	COG1692	metallophosphoesterase
JKA73_RS14640	COG0515	serine threonine protein kinase
JKA73_RS14690	COG1196	nuclear chromosome segregation
JKA73_RS14690	COG0745	RESPONSE REGULATOR receiver
JKA73_RS14705	COG1543	Belongs to the glycosyl hydrolase 57 family
JKA73_RS14710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKA73_RS14725	COG1496	oxidoreductase activity
JKA73_RS14745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JKA73_RS14770	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JKA73_RS14795	COG0490	domain, Protein
JKA73_RS14795	COG0471	metal ion transport
JKA73_RS14800	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JKA73_RS14805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JKA73_RS14815	COG0484	heat shock protein binding
JKA73_RS14820	COG0443	Heat shock 70 kDa protein
JKA73_RS14845	COG0237	dephospho-CoA kinase activity
JKA73_RS14860	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JKA73_RS14885	COG0167	dihydroorotate dehydrogenase activity
JKA73_RS14900	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JKA73_RS14905	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JKA73_RS14920	COG3852	Histidine kinase
JKA73_RS14935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JKA73_RS14945	COG0509	glycine decarboxylation via glycine cleavage system
JKA73_RS14950	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JKA73_RS14950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JKA73_RS14955	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JKA73_RS14980	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS14990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JKA73_RS15015	COG1643	Atp-dependent helicase
JKA73_RS15045	COG0189	ligase activity
JKA73_RS15055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JKA73_RS15080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JKA73_RS15085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JKA73_RS15105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JKA73_RS15110	COG0081	regulation of translation
JKA73_RS15115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JKA73_RS15120	COG0222	ribosome binding
JKA73_RS15125	COG0085	RNA polymerase activity
JKA73_RS15130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JKA73_RS15145	COG0739	heme binding
JKA73_RS15145	COG1196	nuclear chromosome segregation
JKA73_RS15145	COG0741	lytic transglycosylase activity
JKA73_RS15170	COG1381	Involved in DNA repair and RecF pathway recombination
JKA73_RS15185	COG0789	Transcriptional regulator
JKA73_RS15195	COG0515	serine threonine protein kinase
JKA73_RS15195	COG2815	serine threonine protein kinase
JKA73_RS15205	COG0515	serine threonine protein kinase
JKA73_RS15205	COG2815	serine threonine protein kinase
JKA73_RS15210	COG2204	response regulator
JKA73_RS15225	COG5002	protein histidine kinase activity
JKA73_RS15230	COG0515	serine threonine protein kinase
JKA73_RS15235	COG0752	glycyl-tRNA synthetase alpha subunit
JKA73_RS15240	COG0751	glycine-tRNA ligase activity
JKA73_RS15340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JKA73_RS15385	COG1505	serine-type exopeptidase activity
JKA73_RS15455	COG3608	succinylglutamate desuccinylase aspartoacylase
JKA73_RS15455	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JKA73_RS15465	COG2311	Membrane
JKA73_RS15470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JKA73_RS15505	COG1272	protein, Hemolysin III
JKA73_RS15525	COG3590	peptidase
JKA73_RS15535	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JKA73_RS15535	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JKA73_RS15570	COG2354	Protein conserved in bacteria
JKA73_RS15575	COG2130	NADP-dependent
JKA73_RS15585	COG0330	HflC and HflK could
JKA73_RS15605	COG1643	Atp-dependent helicase
JKA73_RS15635	COG4372	Transposase
JKA73_RS15640	COG4584	PFAM Integrase catalytic
JKA73_RS15650	COG3436	PFAM IS66 Orf2 family protein
JKA73_RS15695	COG2826	transposase and inactivated derivatives, IS30 family
JKA73_RS15780	COG0515	serine threonine protein kinase
JKA73_RS15785	COG0515	serine threonine protein kinase
JKA73_RS15815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JKA73_RS15825	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JKA73_RS15830	COG2921	Belongs to the UPF0250 family
JKA73_RS15845	COG0443	Heat shock 70 kDa protein
JKA73_RS15880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JKA73_RS15910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JKA73_RS15910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JKA73_RS15915	COG0425	Belongs to the sulfur carrier protein TusA family
JKA73_RS15920	COG1131	(ABC) transporter
JKA73_RS15930	COG0768	penicillin binding
JKA73_RS15950	COG2204	response regulator
JKA73_RS15955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JKA73_RS15975	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JKA73_RS15980	COG0077	Prephenate dehydratase
JKA73_RS15980	COG1605	Chorismate mutase
JKA73_RS15985	COG0077	Prephenate dehydratase
JKA73_RS15985	COG1605	Chorismate mutase
JKA73_RS15990	COG2153	protein acetylation
JKA73_RS16020	COG0489	protein tyrosine kinase activity
JKA73_RS16025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JKA73_RS16030	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JKA73_RS16055	COG3088	subunit of a heme lyase
JKA73_RS16060	COG3173	Aminoglycoside phosphotransferase
JKA73_RS16070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JKA73_RS16070	COG2755	lipolytic protein G-D-S-L family
JKA73_RS16085	COG5507	3-demethylubiquinone-9 3-methyltransferase
JKA73_RS16120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKA73_RS16125	COG1138	Cytochrome C-type biogenesis protein
JKA73_RS16130	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JKA73_RS16140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JKA73_RS16150	COG1131	(ABC) transporter
JKA73_RS16195	COG0352	thiamine-phosphate diphosphorylase activity
JKA73_RS16200	COG2022	thiamine diphosphate biosynthetic process
JKA73_RS16255	COG2267	carboxylic ester hydrolase activity
JKA73_RS16260	COG0598	Magnesium transport protein CorA
JKA73_RS16310	COG0018	arginyl-trna synthetase
JKA73_RS16315	COG5002	protein histidine kinase activity
JKA73_RS16340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JKA73_RS16345	COG0049	tRNA binding
JKA73_RS16350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JKA73_RS16355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JKA73_RS16360	COG0051	transcription antitermination factor activity, RNA binding
JKA73_RS16365	COG0088	Forms part of the polypeptide exit tunnel
JKA73_RS16370	COG0089	rRNA binding
JKA73_RS16375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JKA73_RS16380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JKA73_RS16385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JKA73_RS16390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JKA73_RS16395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JKA73_RS16400	COG0255	Belongs to the universal ribosomal protein uL29 family
JKA73_RS16405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JKA73_RS16410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JKA73_RS16415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JKA73_RS16425	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JKA73_RS16430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JKA73_RS16435	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JKA73_RS16440	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JKA73_RS16445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JKA73_RS16450	COG1841	ribosomal large subunit assembly
JKA73_RS16455	COG0200	Binds to the 23S rRNA
JKA73_RS16460	COG0201	protein transport
JKA73_RS16465	COG0563	adenylate kinase activity
JKA73_RS16470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JKA73_RS16475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JKA73_RS16480	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JKA73_RS16485	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JKA73_RS16490	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JKA73_RS16495	COG0202	RNA polymerase activity
JKA73_RS16500	COG0203	ribosomal protein L17
JKA73_RS16540	COG2313	pseudouridylate synthase activity
JKA73_RS16545	COG1956	GAF domain-containing protein
JKA73_RS16560	COG0488	(ABC) transporter
JKA73_RS16575	COG0741	lytic transglycosylase activity
JKA73_RS16580	COG1278	Cold shock
JKA73_RS16610	COG0564	pseudouridine synthase activity
JKA73_RS16630	COG1297	OPT oligopeptide transporter protein
JKA73_RS16635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JKA73_RS16650	COG0714	Associated with various cellular activities
JKA73_RS16660	COG0739	heme binding
JKA73_RS16660	COG1196	nuclear chromosome segregation
JKA73_RS16660	COG0741	lytic transglycosylase activity
JKA73_RS16690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JKA73_RS16735	COG1217	gtp-binding protein TYPA
JKA73_RS16740	COG0596	Alpha beta hydrolase
JKA73_RS16745	COG2204	response regulator
JKA73_RS16760	COG0742	ribosomal rna small subunit methyltransferase
JKA73_RS16765	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JKA73_RS16770	COG0436	Aminotransferase
JKA73_RS16780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JKA73_RS16785	COG1902	pentaerythritol trinitrate reductase activity
JKA73_RS16810	COG0242	peptide deformylase activity
JKA73_RS16865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JKA73_RS16870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JKA73_RS16880	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JKA73_RS16885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKA73_RS16885	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKA73_RS16895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JKA73_RS16920	COG3852	Histidine kinase
JKA73_RS16925	COG2132	Multicopper oxidase
JKA73_RS16950	COG2132	Multicopper oxidase
JKA73_RS16960	COG2217	Heavy metal translocating P-type atpase
JKA73_RS17005	COG0626	cystathionine gamma-synthase activity
JKA73_RS17015	COG1058	Belongs to the CinA family
JKA73_RS17015	COG1546	Belongs to the CinA family
JKA73_RS17030	COG3590	peptidase
JKA73_RS17080	COG0745	RESPONSE REGULATOR receiver
JKA73_RS17085	COG5002	protein histidine kinase activity
JKA73_RS17105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JKA73_RS17125	COG3791	Glutathione-dependent formaldehyde-activating
JKA73_RS17130	COG0673	inositol 2-dehydrogenase activity
JKA73_RS17135	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JKA73_RS17140	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS17140	COG3321	synthase
JKA73_RS17140	COG0604	alcohol dehydrogenase
JKA73_RS17160	COG2986	histidine ammonia-lyase
JKA73_RS17165	COG0527	aspartate kinase activity
JKA73_RS17190	COG1215	transferase activity, transferring glycosyl groups
JKA73_RS17205	COG0210	DNA helicase
JKA73_RS17210	COG0443	Heat shock 70 kDa protein
JKA73_RS17240	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JKA73_RS17240	COG2146	nitrite reductase [NAD(P)H] activity
JKA73_RS17275	COG0529	Catalyzes the synthesis of activated sulfate
JKA73_RS17280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JKA73_RS17310	COG3436	PFAM IS66 Orf2 family protein
JKA73_RS17350	COG0631	protein serine/threonine phosphatase activity
JKA73_RS17370	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JKA73_RS17410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKA73_RS17845	COG3239	Fatty acid desaturase
JKA73_RS17860	COG0617	tRNA 3'-terminal CCA addition
JKA73_RS17865	COG0482	sulfurtransferase activity
JKA73_RS17875	COG0776	regulation of translation
JKA73_RS17910	COG0481	GTPase activity
JKA73_RS17915	COG0681	Belongs to the peptidase S26 family
JKA73_RS17920	COG0540	Belongs to the ATCase OTCase family
JKA73_RS17930	COG0505	Belongs to the CarA family
JKA73_RS17955	COG1022	Amp-dependent synthetase and ligase
JKA73_RS17960	COG0372	Belongs to the citrate synthase family
JKA73_RS17965	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JKA73_RS17970	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JKA73_RS17975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JKA73_RS17990	COG2226	methyltransferase
JKA73_RS17995	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JKA73_RS18005	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JKA73_RS18020	COG4948	Mandelate Racemase Muconate Lactonizing
JKA73_RS18025	COG0318	PFAM AMP-dependent synthetase and ligase
JKA73_RS18050	COG5002	protein histidine kinase activity
JKA73_RS18055	COG0538	isocitrate dehydrogenase activity
JKA73_RS18065	COG1053	succinate dehydrogenase
JKA73_RS18070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JKA73_RS18075	COG0045	succinate-CoA ligase (ADP-forming) activity
JKA73_RS18080	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JKA73_RS18090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JKA73_RS18095	COG0228	four-way junction DNA binding
JKA73_RS18100	COG1837	Belongs to the UPF0109 family
JKA73_RS18105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JKA73_RS18110	COG0336	Belongs to the RNA methyltransferase TrmD family
JKA73_RS18115	COG0335	large ribosomal subunit rRNA binding
JKA73_RS18125	COG0792	nuclease activity
JKA73_RS18130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JKA73_RS18145	COG2204	response regulator
JKA73_RS18160	COG0728	peptidoglycan biosynthetic process
JKA73_RS18190	COG1404	Belongs to the peptidase S8 family
JKA73_RS18200	COG0154	amidase activity
JKA73_RS18235	COG2255	four-way junction helicase activity
JKA73_RS18240	COG4305	rare lipoprotein A
JKA73_RS18245	COG2304	oxidoreductase activity
JKA73_RS18265	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS18285	COG1278	Cold shock
JKA73_RS18295	COG0545	Peptidyl-prolyl cis-trans isomerase
JKA73_RS18315	COG0628	permease
JKA73_RS18330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JKA73_RS18335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JKA73_RS18340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JKA73_RS18345	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JKA73_RS18350	COG0072	phenylalanine-tRNA ligase activity
JKA73_RS18355	COG0776	regulation of translation
JKA73_RS18370	COG2826	transposase and inactivated derivatives, IS30 family
JKA73_RS18450	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS18465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JKA73_RS18505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JKA73_RS18510	COG0477	Major facilitator Superfamily
JKA73_RS18515	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JKA73_RS18520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JKA73_RS18525	COG3433	isochorismatase activity
JKA73_RS18525	COG1535	isochorismatase
JKA73_RS18530	COG1021	2,3-dihydroxybenzoate-AMP ligase
JKA73_RS18535	COG1169	isochorismate synthase
JKA73_RS18540	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS18555	COG0577	efflux transmembrane transporter activity
JKA73_RS18565	COG0277	FAD linked oxidase domain protein
JKA73_RS18565	COG0247	lactate metabolic process
JKA73_RS18570	COG0028	Belongs to the TPP enzyme family
JKA73_RS18620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JKA73_RS18635	COG2076	Multidrug Resistance protein
JKA73_RS18665	COG1335	isochorismatase
JKA73_RS18680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JKA73_RS18700	COG3227	Zinc metalloprotease (Elastase)
JKA73_RS18730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JKA73_RS18745	COG0366	Alpha amylase catalytic
JKA73_RS18785	COG0515	serine threonine protein kinase
JKA73_RS18830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKA73_RS18840	COG3706	GGDEF domain
JKA73_RS18850	COG2521	methyltransferase
JKA73_RS18850	COG2136	Putative SAM-dependent methyltransferase
JKA73_RS18875	COG0612	Peptidase, M16
JKA73_RS18885	COG0564	pseudouridine synthase activity
JKA73_RS18900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JKA73_RS18910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JKA73_RS18935	COG0688	phosphatidylethanolamine metabolic process
JKA73_RS18970	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JKA73_RS18980	COG3781	membrane
JKA73_RS18985	COG0745	RESPONSE REGULATOR receiver
JKA73_RS19005	COG2201	protein-glutamate methylesterase activity
JKA73_RS19010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JKA73_RS19010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JKA73_RS19030	COG1830	Aldolase
JKA73_RS19050	COG0456	acetyltransferase
JKA73_RS19055	COG0156	8-amino-7-oxononanoate synthase activity
JKA73_RS19080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JKA73_RS19085	COG3290	protein histidine kinase activity
JKA73_RS19085	COG0840	transmembrane signaling receptor activity
JKA73_RS19095	COG1024	Enoyl-CoA hydratase
JKA73_RS19105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JKA73_RS19110	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS19120	COG0571	ribonuclease III activity
JKA73_RS19135	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JKA73_RS19140	COG1160	GTP binding
JKA73_RS19175	COG1136	(ABC) transporter
JKA73_RS19175	COG0577	efflux transmembrane transporter activity
JKA73_RS19185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JKA73_RS19185	COG0519	Catalyzes the synthesis of GMP from XMP
JKA73_RS19195	COG0517	IMP dehydrogenase activity
JKA73_RS19195	COG0516	GMP reductase activity
JKA73_RS19200	COG0443	Heat shock 70 kDa protein
JKA73_RS19215	COG0586	Pfam SNARE associated Golgi protein
JKA73_RS19225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JKA73_RS19230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JKA73_RS19245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JKA73_RS19255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JKA73_RS19260	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JKA73_RS19265	COG0183	Belongs to the thiolase family
JKA73_RS19280	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS19285	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JKA73_RS19290	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS19300	COG1024	Enoyl-CoA hydratase
JKA73_RS19305	COG1250	3-hydroxyacyl-CoA dehydrogenase
JKA73_RS19320	COG0489	protein tyrosine kinase activity
JKA73_RS19350	COG0430	RNA-3'-phosphate cyclase activity
JKA73_RS19365	COG3852	Histidine kinase
JKA73_RS19430	COG2165	general secretion pathway protein
JKA73_RS19455	COG1946	Acyl-CoA thioesterase
JKA73_RS19470	COG1047	Peptidyl-prolyl cis-trans
JKA73_RS19475	COG3359	exonuclease
JKA73_RS19480	COG1205	dead DEAH box helicase
JKA73_RS19480	COG1111	helicase
JKA73_RS19485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JKA73_RS19500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS19515	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JKA73_RS19520	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JKA73_RS19525	COG0180	Tryptophanyl-tRNA synthetase
JKA73_RS19535	COG4974	Belongs to the 'phage' integrase family
JKA73_RS19545	COG0009	L-threonylcarbamoyladenylate synthase
JKA73_RS19550	COG0475	glutathione-regulated potassium exporter activity
JKA73_RS19550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JKA73_RS19570	COG0398	Pfam SNARE associated Golgi protein
JKA73_RS19600	COG0028	Belongs to the TPP enzyme family
JKA73_RS19605	COG2111	Na H antiporter
JKA73_RS19605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JKA73_RS19610	COG2111	Na H antiporter
JKA73_RS19615	COG1006	Multisubunit Na H antiporter MnhC subunit
JKA73_RS19620	COG0651	ATP synthesis coupled electron transport
JKA73_RS19625	COG1863	multisubunit Na H antiporter MnhE subunit
JKA73_RS19630	COG2212	antiporter activity
JKA73_RS19635	COG1320	monovalent cation:proton antiporter activity
JKA73_RS19650	COG1845	cytochrome c oxidase, subunit III
JKA73_RS19655	COG1845	cytochrome c oxidase, subunit III
JKA73_RS19655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JKA73_RS19660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JKA73_RS19690	COG0437	4 iron, 4 sulfur cluster binding
JKA73_RS19700	COG1301	dicarboxylic acid transport
JKA73_RS19710	COG0784	Response regulator, receiver
JKA73_RS19710	COG4191	Histidine kinase
JKA73_RS19715	COG2814	Major facilitator Superfamily
JKA73_RS19720	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JKA73_RS19775	COG0110	maltose O-acetyltransferase activity
JKA73_RS19785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKA73_RS19795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JKA73_RS19800	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JKA73_RS19835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JKA73_RS19845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JKA73_RS19850	COG1116	anion transmembrane transporter activity
JKA73_RS19850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JKA73_RS19855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JKA73_RS19880	COG0067	glutamate synthase
JKA73_RS19880	COG0069	glutamate synthase activity
JKA73_RS19880	COG0070	glutamate synthase
JKA73_RS19890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JKA73_RS19895	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
JKA73_RS19900	COG4654	Cytochrome c, class I
JKA73_RS19905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JKA73_RS19935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JKA73_RS19950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JKA73_RS19955	COG2226	methyltransferase
JKA73_RS19960	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS19960	COG3321	synthase
JKA73_RS19960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKA73_RS19960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JKA73_RS19960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JKA73_RS19965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JKA73_RS19965	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS19965	COG4221	oxidoreductase activity
JKA73_RS19965	COG3321	synthase
JKA73_RS19975	COG3321	synthase
JKA73_RS19975	COG0300	oxidoreductase activity
JKA73_RS19975	COG4221	oxidoreductase activity
JKA73_RS19975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKA73_RS19980	COG0300	oxidoreductase activity
JKA73_RS19980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKA73_RS19980	COG3321	synthase
JKA73_RS19980	COG4221	oxidoreductase activity
JKA73_RS19990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JKA73_RS19990	COG3321	synthase
JKA73_RS19990	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS19990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKA73_RS19990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JKA73_RS19995	COG1024	Enoyl-CoA hydratase
JKA73_RS20000	COG1024	Enoyl-CoA hydratase
JKA73_RS20005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JKA73_RS20015	COG2124	cytochrome p450
JKA73_RS20025	COG3425	synthase
JKA73_RS20030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKA73_RS20040	COG3425	synthase
JKA73_RS20045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKA73_RS20090	COG0585	pseudouridine synthase activity
JKA73_RS20115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JKA73_RS20125	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS20150	COG0708	Exodeoxyribonuclease III
JKA73_RS20225	COG0488	(ABC) transporter
JKA73_RS20305	COG0667	Aldo Keto reductase
JKA73_RS20380	COG0515	serine threonine protein kinase
JKA73_RS20380	COG2815	serine threonine protein kinase
JKA73_RS20425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JKA73_RS20465	COG0741	lytic transglycosylase activity
JKA73_RS20480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JKA73_RS20485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JKA73_RS20490	COG0825	malonyl-CoA metabolic process
JKA73_RS20525	COG2766	serine protein kinase
JKA73_RS20530	COG0443	Heat shock 70 kDa protein
JKA73_RS20535	COG0515	serine threonine protein kinase
JKA73_RS20545	COG0495	leucyl-tRNA aminoacylation
JKA73_RS20560	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JKA73_RS20575	COG0101	tRNA pseudouridine synthase activity
JKA73_RS20610	COG1606	tRNA processing
JKA73_RS20615	COG0529	Catalyzes the synthesis of activated sulfate
JKA73_RS20615	COG2046	Belongs to the sulfate adenylyltransferase family
JKA73_RS20630	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JKA73_RS20650	COG4585	Histidine kinase
JKA73_RS20665	COG1131	(ABC) transporter
JKA73_RS20680	COG0604	alcohol dehydrogenase
JKA73_RS20680	COG3321	synthase
JKA73_RS20680	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS20700	COG0513	Belongs to the DEAD box helicase family
JKA73_RS20705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JKA73_RS20720	COG1408	metallophosphoesterase
JKA73_RS20780	COG1181	Belongs to the D-alanine--D-alanine ligase family
JKA73_RS20795	COG0113	porphobilinogen synthase activity
JKA73_RS20805	COG1131	(ABC) transporter
JKA73_RS20885	COG0583	DNA-binding transcription factor activity
JKA73_RS20900	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS20925	COG1228	amidohydrolase
JKA73_RS20955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JKA73_RS21020	COG0745	RESPONSE REGULATOR receiver
JKA73_RS21030	COG0686	Belongs to the AlaDH PNT family
JKA73_RS21035	COG1595	DNA-templated transcription, initiation
JKA73_RS21045	COG0745	RESPONSE REGULATOR receiver
JKA73_RS21055	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JKA73_RS21060	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JKA73_RS21060	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JKA73_RS21090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JKA73_RS21100	COG3220	belongs to the UPF0276 family
JKA73_RS21115	COG0745	RESPONSE REGULATOR receiver
JKA73_RS21120	COG2205	protein histidine kinase activity
JKA73_RS21160	COG1136	(ABC) transporter
JKA73_RS21160	COG0577	efflux transmembrane transporter activity
JKA73_RS21165	COG1136	(ABC) transporter
JKA73_RS21165	COG0577	efflux transmembrane transporter activity
JKA73_RS21170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JKA73_RS21185	COG0542	response to heat
JKA73_RS21220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JKA73_RS21230	COG3876	Protein conserved in bacteria
JKA73_RS21245	COG1193	negative regulation of DNA recombination
JKA73_RS21265	COG2204	response regulator
JKA73_RS21270	COG4191	Histidine kinase
JKA73_RS21280	COG1136	(ABC) transporter
JKA73_RS21285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JKA73_RS21290	COG1136	(ABC) transporter
JKA73_RS21290	COG0577	efflux transmembrane transporter activity
JKA73_RS21295	COG0693	protein deglycase activity
JKA73_RS21300	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS21305	COG1408	metallophosphoesterase
JKA73_RS21320	COG0557	exoribonuclease II activity
JKA73_RS21330	COG0303	'Molybdopterin
JKA73_RS21335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKA73_RS21335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKA73_RS21360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JKA73_RS21365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JKA73_RS21380	COG0140	phosphoribosyl-ATP diphosphatase activity
JKA73_RS21380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JKA73_RS21390	COG0107	imidazoleglycerol-phosphate synthase activity
JKA73_RS21395	COG0131	Imidazoleglycerol-phosphate dehydratase
JKA73_RS21400	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JKA73_RS21405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JKA73_RS21410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JKA73_RS21415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JKA73_RS21420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JKA73_RS21425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JKA73_RS21425	COG2022	thiamine diphosphate biosynthetic process
JKA73_RS21430	COG2199	diguanylate cyclase activity
JKA73_RS21430	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JKA73_RS21445	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JKA73_RS21450	COG0517	IMP dehydrogenase activity
JKA73_RS21450	COG0617	tRNA 3'-terminal CCA addition
JKA73_RS21450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JKA73_RS21455	COG0471	metal ion transport
JKA73_RS21465	COG2204	response regulator
JKA73_RS21485	COG4191	Histidine kinase
JKA73_RS21490	COG4566	intracellular signal transduction
JKA73_RS21490	COG0745	RESPONSE REGULATOR receiver
JKA73_RS21495	COG2205	protein histidine kinase activity
JKA73_RS21515	COG3852	Histidine kinase
JKA73_RS21560	COG2204	response regulator
JKA73_RS21565	COG4191	Histidine kinase
JKA73_RS21570	COG1309	transcriptional regulator
JKA73_RS21575	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JKA73_RS21590	COG3425	synthase
JKA73_RS21595	COG0071	Belongs to the small heat shock protein (HSP20) family
JKA73_RS21655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKA73_RS21725	COG0003	Pfam Anion-transporting ATPase
JKA73_RS21765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JKA73_RS21775	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS21780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JKA73_RS21820	COG0737	Belongs to the 5'-nucleotidase family
JKA73_RS21850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKA73_RS21860	COG0730	response to heat
JKA73_RS21900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JKA73_RS21920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JKA73_RS21940	COG0406	alpha-ribazole phosphatase activity
JKA73_RS21940	COG0494	nUDIX hydrolase
JKA73_RS21950	COG0515	serine threonine protein kinase
JKA73_RS21960	COG2204	response regulator
JKA73_RS21980	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JKA73_RS21990	COG1228	amidohydrolase
JKA73_RS21995	COG0121	glutamine amidotransferase
JKA73_RS22000	COG0802	atpase or kinase
JKA73_RS22005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JKA73_RS22005	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JKA73_RS22010	COG0736	holo-[acyl-carrier-protein] synthase activity
JKA73_RS22015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JKA73_RS22020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JKA73_RS22025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JKA73_RS22035	COG2353	YceI-like domain
JKA73_RS22040	COG0583	DNA-binding transcription factor activity
JKA73_RS22045	COG1741	Belongs to the pirin family
JKA73_RS22050	COG1741	Belongs to the pirin family
JKA73_RS22055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JKA73_RS22060	COG0037	tRNA processing
JKA73_RS22100	COG2226	methyltransferase
JKA73_RS22110	COG0515	serine threonine protein kinase
JKA73_RS22110	COG2815	serine threonine protein kinase
JKA73_RS22130	COG0515	serine threonine protein kinase
JKA73_RS22180	COG3246	L-lysine catabolic process to acetate
JKA73_RS22185	COG1607	acyl-coa hydrolase
JKA73_RS22190	COG5012	cobalamin binding
JKA73_RS22200	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JKA73_RS22205	COG0753	catalase activity
JKA73_RS22215	COG0604	alcohol dehydrogenase
JKA73_RS22225	COG1573	uracil-dna glycosylase
JKA73_RS22235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JKA73_RS22250	COG0631	protein serine/threonine phosphatase activity
JKA73_RS22300	COG0318	PFAM AMP-dependent synthetase and ligase
JKA73_RS22305	COG1742	UPF0060 membrane protein
JKA73_RS22370	COG2119	membrane
JKA73_RS22395	COG4464	protein tyrosine phosphatase activity
JKA73_RS22400	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JKA73_RS22415	COG0010	Belongs to the arginase family
JKA73_RS22425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKA73_RS22430	COG0515	serine threonine protein kinase
JKA73_RS22430	COG2815	serine threonine protein kinase
JKA73_RS22435	COG3268	Saccharopine dehydrogenase
JKA73_RS22450	COG0745	RESPONSE REGULATOR receiver
JKA73_RS22485	COG5002	protein histidine kinase activity
JKA73_RS22490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JKA73_RS22505	COG0739	heme binding
JKA73_RS22510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JKA73_RS22515	COG0148	phosphopyruvate hydratase activity
JKA73_RS22535	COG1494	fructose-1,6-bisphosphatase
JKA73_RS22540	COG0824	Thioesterase
JKA73_RS22545	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
JKA73_RS22555	COG0525	valine-tRNA ligase activity
JKA73_RS22570	COG3706	GGDEF domain
JKA73_RS22590	COG0459	protein refolding
JKA73_RS22650	COG2815	serine threonine protein kinase
JKA73_RS22650	COG0515	serine threonine protein kinase
JKA73_RS22790	COG1222	aaa ATPase
JKA73_RS22800	COG4221	oxidoreductase activity
JKA73_RS22830	COG3119	arylsulfatase activity
JKA73_RS22850	COG0604	alcohol dehydrogenase
JKA73_RS22850	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS22850	COG3321	synthase
JKA73_RS22945	COG1032	radical SAM domain protein
JKA73_RS22975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JKA73_RS23010	COG0515	serine threonine protein kinase
JKA73_RS23020	COG4771	TonB-dependent receptor
JKA73_RS23035	COG2208	phosphoserine phosphatase activity
JKA73_RS23035	COG2770	Histidine kinase
JKA73_RS23040	COG0750	zinc metalloprotease
JKA73_RS23050	COG0022	dehydrogenase e1 component
JKA73_RS23110	COG1042	CoA-binding domain protein
JKA73_RS23110	COG0045	succinate-CoA ligase (ADP-forming) activity
JKA73_RS23110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKA73_RS23135	COG2885	chlorophyll binding
JKA73_RS23150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JKA73_RS23150	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JKA73_RS23155	COG0343	queuine tRNA-ribosyltransferase activity
JKA73_RS23160	COG0488	(ABC) transporter
JKA73_RS23170	COG1295	ribonuclease BN
JKA73_RS23195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JKA73_RS23215	COG1032	radical SAM domain protein
JKA73_RS23275	COG0477	Major facilitator Superfamily
JKA73_RS23310	COG1216	Glycosyl transferase, family 2
JKA73_RS23315	COG0463	Glycosyl transferase, family 2
JKA73_RS23325	COG1215	transferase activity, transferring glycosyl groups
JKA73_RS23370	COG0741	lytic transglycosylase activity
JKA73_RS23395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JKA73_RS23440	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JKA73_RS23445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JKA73_RS23450	COG0142	geranyltranstransferase activity
JKA73_RS23465	COG1570	exodeoxyribonuclease VII activity
JKA73_RS23550	COG4608	Belongs to the ABC transporter superfamily
JKA73_RS23555	COG0444	Belongs to the ABC transporter superfamily
JKA73_RS23575	COG0811	peptide transport
JKA73_RS23585	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS23595	COG2030	dehydratase
JKA73_RS23610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JKA73_RS23620	COG0714	Associated with various cellular activities
JKA73_RS23630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKA73_RS23635	COG1193	negative regulation of DNA recombination
JKA73_RS23675	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JKA73_RS23675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JKA73_RS23685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JKA73_RS23690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JKA73_RS23695	COG1862	Preprotein translocase
JKA73_RS23700	COG0343	queuine tRNA-ribosyltransferase activity
JKA73_RS23705	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JKA73_RS23710	COG2385	sporulation resulting in formation of a cellular spore
JKA73_RS23740	COG0515	serine threonine protein kinase
JKA73_RS23770	COG0194	GDP metabolic process
JKA73_RS23775	COG1561	YicC-like family, N-terminal region
JKA73_RS23785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JKA73_RS23785	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JKA73_RS23795	COG1663	tetraacyldisaccharide 4'-kinase activity
JKA73_RS23820	COG1132	(ABC) transporter
JKA73_RS23830	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JKA73_RS23840	COG2095	MarC family integral membrane protein
JKA73_RS23860	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JKA73_RS23865	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JKA73_RS23870	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JKA73_RS23880	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JKA73_RS23885	COG1136	(ABC) transporter
JKA73_RS23895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JKA73_RS23905	COG1595	DNA-templated transcription, initiation
JKA73_RS23910	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JKA73_RS23920	COG0662	Cupin 2, conserved barrel domain protein
JKA73_RS23920	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JKA73_RS23925	COG1480	7TM receptor with intracellular HD hydrolase
JKA73_RS23945	COG3956	TIGRFAM MazG family protein
JKA73_RS23950	COG0268	Binds directly to 16S ribosomal RNA
JKA73_RS23965	COG0495	leucyl-tRNA aminoacylation
JKA73_RS23970	COG1629	transport
JKA73_RS23980	COG2084	Dehydrogenase
JKA73_RS23990	COG1131	(ABC) transporter
JKA73_RS23995	COG0745	RESPONSE REGULATOR receiver
JKA73_RS24000	COG2201	protein-glutamate methylesterase activity
JKA73_RS24005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JKA73_RS24020	COG0835	chemotaxis
JKA73_RS24030	COG2198	Histidine kinase
JKA73_RS24030	COG0643	Histidine kinase
JKA73_RS24030	COG0784	Response regulator, receiver
JKA73_RS24030	COG0643	Histidine kinase
JKA73_RS24030	COG0784	Response regulator, receiver
JKA73_RS24030	COG2198	Histidine kinase
JKA73_RS24035	COG0745	RESPONSE REGULATOR receiver
JKA73_RS24045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JKA73_RS24050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JKA73_RS24060	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JKA73_RS24060	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JKA73_RS24065	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JKA73_RS24070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JKA73_RS24075	COG0698	ribose 5-phosphate isomerase
JKA73_RS24080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JKA73_RS24085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKA73_RS24090	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS24095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JKA73_RS24100	COG0416	fatty acid biosynthetic process
JKA73_RS24105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JKA73_RS24110	COG1399	metal-binding, possibly nucleic acid-binding protein
JKA73_RS24125	COG0745	RESPONSE REGULATOR receiver
JKA73_RS24130	COG5002	protein histidine kinase activity
JKA73_RS24140	COG2062	phosphohistidine phosphatase, SixA
JKA73_RS24150	COG0730	response to heat
JKA73_RS24160	COG0659	secondary active sulfate transmembrane transporter activity
JKA73_RS24165	COG2204	response regulator
JKA73_RS24170	COG5002	protein histidine kinase activity
JKA73_RS24175	COG0745	RESPONSE REGULATOR receiver
JKA73_RS24185	COG0573	inorganic phosphate transmembrane transporter activity
JKA73_RS24190	COG0581	inorganic phosphate transmembrane transporter activity
JKA73_RS24195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JKA73_RS24215	COG1253	flavin adenine dinucleotide binding
JKA73_RS24240	COG3047	cAMP biosynthetic process
JKA73_RS24240	COG2885	chlorophyll binding
JKA73_RS24290	COG3157	Type VI secretion system effector, Hcp
JKA73_RS24335	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JKA73_RS24340	COG4208	sulfate ABC transporter
JKA73_RS24355	COG0542	response to heat
JKA73_RS24375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JKA73_RS24395	COG0542	response to heat
JKA73_RS24410	COG0477	Major facilitator Superfamily
JKA73_RS24420	COG0154	amidase activity
JKA73_RS24425	COG0514	ATP-dependent DNA helicase (RecQ)
JKA73_RS24465	COG2815	serine threonine protein kinase
JKA73_RS24465	COG0515	serine threonine protein kinase
JKA73_RS24495	COG0210	DNA helicase
JKA73_RS24505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JKA73_RS24585	COG1324	tolerance protein
JKA73_RS24600	COG0527	aspartate kinase activity
JKA73_RS24650	COG2223	nitrite transmembrane transporter activity
JKA73_RS24665	COG1758	RNA polymerase activity
JKA73_RS24685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JKA73_RS24690	COG0459	protein refolding
JKA73_RS24710	COG3829	transcription factor binding
JKA73_RS24720	COG1196	nuclear chromosome segregation
JKA73_RS24725	COG1253	flavin adenine dinucleotide binding
JKA73_RS24735	COG2843	Capsule synthesis protein
JKA73_RS24740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JKA73_RS24745	COG2890	protein-(glutamine-N5) methyltransferase activity
JKA73_RS24750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JKA73_RS24785	COG2124	cytochrome p450
JKA73_RS24805	COG2264	protein methyltransferase activity
JKA73_RS24835	COG1231	oxidoreductase activity
JKA73_RS24920	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JKA73_RS24970	COG3800	Transcriptional regulator
JKA73_RS24970	COG1396	sequence-specific DNA binding
JKA73_RS24985	COG0730	response to heat
JKA73_RS24995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JKA73_RS25010	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JKA73_RS25010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JKA73_RS25015	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JKA73_RS25025	COG2255	four-way junction helicase activity
JKA73_RS25040	COG0632	four-way junction helicase activity
JKA73_RS25045	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JKA73_RS25050	COG0217	transcriptional regulatory protein
JKA73_RS25065	COG2204	response regulator
JKA73_RS25080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JKA73_RS25085	COG0430	RNA-3'-phosphate cyclase activity
JKA73_RS25090	COG1690	Belongs to the RtcB family
JKA73_RS25095	COG4650	regulator
JKA73_RS25115	COG2205	protein histidine kinase activity
JKA73_RS25165	COG3011	Protein conserved in bacteria
JKA73_RS25185	COG1104	cysteine desulfurase activity
JKA73_RS25190	COG0822	iron-sulfur transferase activity
JKA73_RS25195	COG0316	Belongs to the HesB IscA family
JKA73_RS25210	COG0633	Ferredoxin
JKA73_RS25270	COG1304	FMN binding
JKA73_RS25300	COG0501	Belongs to the peptidase M48B family
JKA73_RS25310	COG1846	Transcriptional regulator
JKA73_RS25335	COG5002	protein histidine kinase activity
JKA73_RS25340	COG0612	Peptidase, M16
JKA73_RS25365	COG1012	belongs to the aldehyde dehydrogenase family
JKA73_RS25370	COG3604	Transcriptional regulator
JKA73_RS25375	COG2885	chlorophyll binding
JKA73_RS25385	COG0457	Tetratricopeptide repeat
JKA73_RS25385	COG0515	serine threonine protein kinase
JKA73_RS25400	COG2204	response regulator
JKA73_RS25415	COG0745	RESPONSE REGULATOR receiver
JKA73_RS25445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JKA73_RS25540	COG1280	lysine exporter protein (LysE YggA)
JKA73_RS25545	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JKA73_RS25555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JKA73_RS25560	COG1435	thymidine kinase activity
JKA73_RS25570	COG2088	sporulation resulting in formation of a cellular spore
JKA73_RS25575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JKA73_RS25580	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JKA73_RS25585	COG0193	aminoacyl-tRNA hydrolase activity
JKA73_RS25590	COG0360	Binds together with S18 to 16S ribosomal RNA
JKA73_RS25595	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JKA73_RS25600	COG0359	binds to the 23S rRNA
JKA73_RS25610	COG3275	phosphorelay sensor kinase activity
JKA73_RS25615	COG3279	Response regulator of the LytR AlgR family
JKA73_RS25625	COG0352	thiamine-phosphate diphosphorylase activity
JKA73_RS25625	COG0351	phosphomethylpyrimidine kinase
JKA73_RS25625	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JKA73_RS25630	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JKA73_RS25635	COG0352	thiamine-phosphate diphosphorylase activity
JKA73_RS25660	COG0542	response to heat
JKA73_RS25670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JKA73_RS25680	COG2311	Membrane
JKA73_RS25695	COG1733	regulation of RNA biosynthetic process
JKA73_RS25700	COG0702	epimerase
JKA73_RS25715	COG1438	arginine binding
JKA73_RS25720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JKA73_RS25725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JKA73_RS25735	COG0165	Argininosuccinate lyase
JKA73_RS25740	COG0137	argininosuccinate synthase activity
JKA73_RS25750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JKA73_RS25780	COG0515	serine threonine protein kinase
JKA73_RS25800	COG0789	Transcriptional regulator
JKA73_RS25815	COG5002	protein histidine kinase activity
JKA73_RS25820	COG2204	response regulator
JKA73_RS25825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS25835	COG3186	Phenylalanine-4-hydroxylase
JKA73_RS25870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JKA73_RS25875	COG0183	Belongs to the thiolase family
JKA73_RS25880	COG1250	3-hydroxyacyl-CoA dehydrogenase
JKA73_RS25880	COG1024	Enoyl-CoA hydratase
JKA73_RS25895	COG0254	rRNA binding
JKA73_RS25910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JKA73_RS25915	COG2201	protein-glutamate methylesterase activity
JKA73_RS25955	COG2885	chlorophyll binding
JKA73_RS25960	COG2204	response regulator
JKA73_RS25995	COG0443	Heat shock 70 kDa protein
JKA73_RS26005	COG2135	peptidase activity
JKA73_RS26020	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JKA73_RS26040	COG1132	(ABC) transporter
JKA73_RS26045	COG0577	efflux transmembrane transporter activity
JKA73_RS26070	COG0641	radical SAM
JKA73_RS26090	COG2815	serine threonine protein kinase
JKA73_RS26090	COG0515	serine threonine protein kinase
JKA73_RS26125	COG5000	phosphorelay sensor kinase activity
JKA73_RS26175	COG2885	chlorophyll binding
JKA73_RS26175	COG3047	cAMP biosynthetic process
JKA73_RS26190	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JKA73_RS26190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JKA73_RS26195	COG0252	asparaginase activity
JKA73_RS26240	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS26250	COG1309	transcriptional regulator
JKA73_RS26260	COG0745	RESPONSE REGULATOR receiver
JKA73_RS26315	COG3436	PFAM IS66 Orf2 family protein
JKA73_RS26335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JKA73_RS26340	COG0513	Belongs to the DEAD box helicase family
JKA73_RS26350	COG0564	pseudouridine synthase activity
JKA73_RS26375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JKA73_RS26385	COG3942	CHAP domain
JKA73_RS26385	COG1388	LysM domain
JKA73_RS26400	COG3059	membrane
JKA73_RS26440	COG0412	Dienelactone hydrolase
JKA73_RS26620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JKA73_RS26675	COG2909	trisaccharide binding
JKA73_RS26710	COG1278	Cold shock
JKA73_RS26725	COG0745	RESPONSE REGULATOR receiver
JKA73_RS26730	COG2205	protein histidine kinase activity
JKA73_RS26745	COG1131	(ABC) transporter
JKA73_RS26750	COG0109	protoheme IX farnesyltransferase activity
JKA73_RS26775	COG0443	Heat shock 70 kDa protein
JKA73_RS26785	COG0737	Belongs to the 5'-nucleotidase family
JKA73_RS26840	COG0493	'glutamate synthase
JKA73_RS26840	COG0543	2 iron, 2 sulfur cluster binding
JKA73_RS26850	COG2062	phosphohistidine phosphatase, SixA
JKA73_RS26865	COG0233	cytoplasmic translational termination
JKA73_RS26870	COG0528	UMP kinase activity
JKA73_RS26875	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JKA73_RS26880	COG0052	Belongs to the universal ribosomal protein uS2 family
JKA73_RS26885	COG0653	protein targeting
JKA73_RS26890	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JKA73_RS26900	COG0739	heme binding
JKA73_RS26905	COG0631	protein serine/threonine phosphatase activity
JKA73_RS26910	COG0497	DNA recombination
JKA73_RS26915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKA73_RS26920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JKA73_RS26945	COG2814	Major facilitator Superfamily
JKA73_RS26950	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JKA73_RS26960	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JKA73_RS26975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JKA73_RS26995	COG1215	transferase activity, transferring glycosyl groups
JKA73_RS27000	COG3394	polysaccharide catabolic process
JKA73_RS27005	COG2813	Specifically methylates the guanine in position
JKA73_RS27015	COG1250	3-hydroxyacyl-CoA dehydrogenase
JKA73_RS27015	COG1024	Enoyl-CoA hydratase
JKA73_RS27020	COG0183	Belongs to the thiolase family
JKA73_RS27025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JKA73_RS27030	COG1874	Beta-galactosidase
JKA73_RS27030	COG0366	Alpha amylase catalytic
JKA73_RS27045	COG3842	ATPase activity
JKA73_RS27050	COG1175	transmembrane transport
JKA73_RS27125	COG2267	carboxylic ester hydrolase activity
JKA73_RS27130	COG5640	endopeptidase activity
JKA73_RS27190	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JKA73_RS27205	COG4941	Belongs to the sigma-70 factor family
JKA73_RS27215	COG0501	Belongs to the peptidase M48B family
JKA73_RS27245	COG1051	belongs to the nudix hydrolase family
JKA73_RS27260	COG0590	tRNA wobble adenosine to inosine editing
JKA73_RS27325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JKA73_RS27350	COG3227	Zinc metalloprotease (Elastase)
JKA73_RS27420	COG1505	serine-type exopeptidase activity
JKA73_RS27435	COG0429	hydrolase of the alpha beta-hydrolase fold
JKA73_RS27510	COG0612	Peptidase, M16
JKA73_RS27520	COG1652	LysM domain
JKA73_RS27540	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JKA73_RS27580	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JKA73_RS27595	COG0583	DNA-binding transcription factor activity
JKA73_RS27600	COG4249	Peptidase C14 caspase catalytic subunit p20
JKA73_RS27600	COG2319	Wd-40 repeat
JKA73_RS27645	COG1126	abc transporter atp-binding protein
JKA73_RS27650	COG0765	amino acid transport
JKA73_RS27660	COG0745	RESPONSE REGULATOR receiver
JKA73_RS27685	COG1032	radical SAM domain protein
JKA73_RS27745	COG5380	lipid catabolic process
JKA73_RS27760	COG1671	Belongs to the UPF0178 family
JKA73_RS27775	COG0588	phosphoglycerate mutase activity
JKA73_RS27790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JKA73_RS27835	COG3278	Belongs to the heme-copper respiratory oxidase family
JKA73_RS27855	COG1309	transcriptional regulator
JKA73_RS27865	COG1309	transcriptional regulator
JKA73_RS27875	COG1024	Enoyl-CoA hydratase
JKA73_RS27885	COG0653	protein targeting
JKA73_RS27890	COG0673	inositol 2-dehydrogenase activity
JKA73_RS27915	COG0437	4 iron, 4 sulfur cluster binding
JKA73_RS27940	COG1858	cytochrome C peroxidase
JKA73_RS27955	COG3030	protein affecting phage T7 exclusion by the F plasmid
JKA73_RS27965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JKA73_RS27975	COG1929	Belongs to the glycerate kinase type-1 family
JKA73_RS28000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JKA73_RS28020	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JKA73_RS28080	COG0745	RESPONSE REGULATOR receiver
JKA73_RS28085	COG1024	Enoyl-CoA hydratase
JKA73_RS28090	COG0511	ligase activity, forming carbon-carbon bonds
JKA73_RS28095	COG0439	Biotin carboxylase
JKA73_RS28105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JKA73_RS28120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JKA73_RS28125	COG1181	Belongs to the D-alanine--D-alanine ligase family
JKA73_RS28130	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JKA73_RS28135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JKA73_RS28140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JKA73_RS28150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JKA73_RS28155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JKA73_RS28160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JKA73_RS28165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JKA73_RS28175	COG3116	cell division
JKA73_RS28180	COG0275	rRNA processing
JKA73_RS28190	COG2001	Belongs to the MraZ family
JKA73_RS28200	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS28220	COG0515	serine threonine protein kinase
JKA73_RS28275	COG0519	Catalyzes the synthesis of GMP from XMP
JKA73_RS28275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JKA73_RS28290	COG0628	permease
JKA73_RS28300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JKA73_RS28305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JKA73_RS28310	COG1254	Belongs to the acylphosphatase family
JKA73_RS28325	COG1295	ribonuclease BN
JKA73_RS28340	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JKA73_RS28350	COG1987	bacterial-type flagellum assembly
JKA73_RS28365	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JKA73_RS28375	COG4669	(LipO)protein
JKA73_RS28395	COG0745	RESPONSE REGULATOR receiver
JKA73_RS28425	COG2304	oxidoreductase activity
JKA73_RS28445	COG0714	Associated with various cellular activities
JKA73_RS28460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKA73_RS28470	COG2204	response regulator
JKA73_RS28485	COG4968	Prepilin-type N-terminal cleavage methylation domain
JKA73_RS28515	COG2204	response regulator
JKA73_RS28550	COG0668	transmembrane transport
JKA73_RS28560	COG0737	Belongs to the 5'-nucleotidase family
JKA73_RS28565	COG1388	LysM domain
JKA73_RS28565	COG0741	lytic transglycosylase activity
JKA73_RS28595	COG0515	serine threonine protein kinase
JKA73_RS28610	COG1136	(ABC) transporter
JKA73_RS28635	COG2205	protein histidine kinase activity
JKA73_RS28640	COG0402	S-adenosylhomocysteine deaminase activity
JKA73_RS28645	COG0295	cytidine deaminase activity
JKA73_RS28670	COG1744	ABC transporter substrate-binding protein PnrA-like
JKA73_RS28675	COG3845	ABC transporter
JKA73_RS28680	COG4603	Belongs to the binding-protein-dependent transport system permease family
JKA73_RS28685	COG1079	Belongs to the binding-protein-dependent transport system permease family
JKA73_RS28690	COG4191	Histidine kinase
JKA73_RS28700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JKA73_RS28710	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JKA73_RS28770	COG4941	Belongs to the sigma-70 factor family
JKA73_RS28790	COG0552	protein localization to endoplasmic reticulum
JKA73_RS28815	COG1215	transferase activity, transferring glycosyl groups
JKA73_RS28820	COG1181	Belongs to the D-alanine--D-alanine ligase family
JKA73_RS28835	COG0793	Belongs to the peptidase S41A family
JKA73_RS28840	COG0508	dehydrogenase complex catalyzes the overall conversion of
JKA73_RS28840	COG0596	Alpha beta hydrolase
JKA73_RS28850	COG2177	Part of the ABC transporter FtsEX involved in
JKA73_RS28855	COG2884	Cell division ATP-binding protein ftsE
JKA73_RS28870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JKA73_RS28880	COG0811	peptide transport
JKA73_RS28895	COG0823	Involved in the tonB-independent uptake of proteins
JKA73_RS28915	COG2223	nitrite transmembrane transporter activity
JKA73_RS28930	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JKA73_RS28940	COG3267	Type II secretory pathway component ExeA
JKA73_RS28940	COG3409	Peptidoglycan-binding domain 1 protein
JKA73_RS28950	COG0439	Biotin carboxylase
JKA73_RS28955	COG0511	ligase activity, forming carbon-carbon bonds
JKA73_RS28960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JKA73_RS29000	COG2204	response regulator
JKA73_RS29005	COG3852	Histidine kinase
JKA73_RS29010	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JKA73_RS29020	COG1131	(ABC) transporter
JKA73_RS29030	COG4968	Prepilin-type N-terminal cleavage methylation domain
JKA73_RS29040	COG3852	Histidine kinase
JKA73_RS29045	COG1459	type II secretion system
JKA73_RS29055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JKA73_RS29065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JKA73_RS29090	COG1199	ATP-dependent helicase activity
JKA73_RS29110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JKA73_RS29125	COG0443	Heat shock 70 kDa protein
JKA73_RS29135	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JKA73_RS29145	COG0793	Belongs to the peptidase S41A family
JKA73_RS29155	COG0584	glycerophosphoryl diester phosphodiesterase
JKA73_RS29160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JKA73_RS29180	COG1192	Involved in chromosome partitioning
JKA73_RS29195	COG0003	Pfam Anion-transporting ATPase
JKA73_RS29220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JKA73_RS29235	COG2766	serine protein kinase
JKA73_RS29240	COG2718	Belongs to the UPF0229 family
JKA73_RS29245	COG2719	SpoVR family
JKA73_RS29250	COG0739	heme binding
JKA73_RS29260	COG0058	SHG alpha-glucan phosphorylase activity
JKA73_RS29285	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS29290	COG0826	peptidase U32
JKA73_RS29295	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JKA73_RS29300	COG1024	Enoyl-CoA hydratase
JKA73_RS29315	COG0587	DNA-directed DNA polymerase activity
JKA73_RS29430	COG4191	Histidine kinase
JKA73_RS29450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JKA73_RS29460	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JKA73_RS29465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS29470	COG3453	Protein conserved in bacteria
JKA73_RS29470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKA73_RS29480	COG2032	superoxide dismutase activity
JKA73_RS29535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JKA73_RS29540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JKA73_RS29555	COG2353	YceI-like domain
JKA73_RS29560	COG3384	dioxygenase
JKA73_RS29585	COG0183	Belongs to the thiolase family
JKA73_RS29620	COG3189	MarR family transcriptional regulator
JKA73_RS29625	COG1012	belongs to the aldehyde dehydrogenase family
JKA73_RS29660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JKA73_RS29660	COG2169	Transcriptional regulator
JKA73_RS29670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JKA73_RS29680	COG0805	protein transport
JKA73_RS29680	COG0805	protein transport
JKA73_RS29685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JKA73_RS29695	COG0840	transmembrane signaling receptor activity
JKA73_RS29700	COG0123	including yeast histone deacetylase and acetoin utilization protein
JKA73_RS29705	COG0300	oxidoreductase activity
JKA73_RS29710	COG0284	orotidine-5'-phosphate decarboxylase activity
JKA73_RS29720	COG0564	pseudouridine synthase activity
JKA73_RS29735	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JKA73_RS29735	COG1793	dna ligase
JKA73_RS29760	COG2086	electron transfer activity
JKA73_RS29765	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS29770	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JKA73_RS29775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JKA73_RS29775	COG0517	IMP dehydrogenase activity
JKA73_RS29790	COG0179	Fumarylacetoacetate (FAA) hydrolase
JKA73_RS29795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JKA73_RS29800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JKA73_RS29805	COG0019	diaminopimelate decarboxylase activity
JKA73_RS29825	COG4783	chaperone-mediated protein folding
JKA73_RS29830	COG1295	ribonuclease BN
JKA73_RS29835	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JKA73_RS29850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKA73_RS29865	COG0697	spore germination
JKA73_RS29875	COG2096	Adenosyltransferase
JKA73_RS29880	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JKA73_RS29885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JKA73_RS29900	COG0672	)-iron permease
JKA73_RS29920	COG1078	dGTPase activity
JKA73_RS29925	COG1181	Belongs to the D-alanine--D-alanine ligase family
JKA73_RS29940	COG1331	Highly conserved protein containing a thioredoxin domain
JKA73_RS29950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JKA73_RS30035	COG0596	Alpha beta hydrolase
JKA73_RS30035	COG0508	dehydrogenase complex catalyzes the overall conversion of
JKA73_RS30045	COG0515	serine threonine protein kinase
JKA73_RS30065	COG0037	tRNA processing
JKA73_RS30075	COG0308	aminopeptidase N
JKA73_RS30105	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JKA73_RS30115	COG2205	protein histidine kinase activity
JKA73_RS30125	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JKA73_RS30130	COG0251	oxidation-reduction process
JKA73_RS30145	COG5002	protein histidine kinase activity
JKA73_RS30145	COG3850	Histidine kinase
JKA73_RS30165	COG4607	ABC-type enterochelin transport system periplasmic component
JKA73_RS30180	COG1131	(ABC) transporter
JKA73_RS30200	COG4377	Putative membrane peptidase family (DUF2324)
JKA73_RS30220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JKA73_RS30235	COG4191	Histidine kinase
JKA73_RS30240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JKA73_RS30285	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JKA73_RS30290	COG0542	response to heat
JKA73_RS30300	COG2201	protein-glutamate methylesterase activity
JKA73_RS30325	COG2205	protein histidine kinase activity
JKA73_RS30325	COG2198	Histidine kinase
JKA73_RS30325	COG0784	Response regulator, receiver
JKA73_RS30330	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JKA73_RS30340	COG0508	dehydrogenase complex catalyzes the overall conversion of
JKA73_RS30345	COG1278	Cold shock
JKA73_RS30365	COG4935	Belongs to the peptidase S8 family
JKA73_RS30365	COG1404	Belongs to the peptidase S8 family
JKA73_RS30370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JKA73_RS30375	COG2815	serine threonine protein kinase
JKA73_RS30375	COG0515	serine threonine protein kinase
JKA73_RS30380	COG4771	TonB-dependent receptor
JKA73_RS30395	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JKA73_RS30400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JKA73_RS30415	COG0326	Molecular chaperone. Has ATPase activity
JKA73_RS30425	COG2205	protein histidine kinase activity
JKA73_RS30435	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JKA73_RS30460	COG1233	COG1233 Phytoene dehydrogenase and related
JKA73_RS30465	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JKA73_RS30470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JKA73_RS30475	COG0134	indole-3-glycerol-phosphate synthase activity
JKA73_RS30480	COG0135	phosphoribosylanthranilate isomerase activity
JKA73_RS30485	COG0133	tryptophan synthase activity
JKA73_RS30490	COG0159	tryptophan synthase activity
JKA73_RS30530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JKA73_RS30530	COG1793	dna ligase
JKA73_RS30555	COG0437	4 iron, 4 sulfur cluster binding
JKA73_RS30590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JKA73_RS30635	COG0429	hydrolase of the alpha beta-hydrolase fold
JKA73_RS30675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JKA73_RS30700	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JKA73_RS30715	COG0546	phosphoglycolate phosphatase activity
JKA73_RS30740	COG2205	protein histidine kinase activity
JKA73_RS30775	COG0322	excinuclease ABC activity
JKA73_RS30790	COG4584	PFAM Integrase catalytic
JKA73_RS30835	COG3344	reverse transcriptase
JKA73_RS30865	COG3436	PFAM IS66 Orf2 family protein
JKA73_RS30870	COG4372	Transposase
JKA73_RS30930	COG2076	Multidrug Resistance protein
JKA73_RS30960	COG4566	intracellular signal transduction
JKA73_RS30965	COG4191	Histidine kinase
JKA73_RS30975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JKA73_RS30975	COG2755	lipolytic protein G-D-S-L family
JKA73_RS31000	COG1741	Belongs to the pirin family
JKA73_RS31080	COG0544	peptidyl-prolyl cis-trans isomerase activity
JKA73_RS31090	COG2824	Alkylphosphonate utilization operon protein PhnA
JKA73_RS31105	COG0785	Cytochrome C biogenesis protein
JKA73_RS31120	COG2188	Transcriptional regulator
JKA73_RS31125	COG0730	response to heat
JKA73_RS31135	COG0500	methyltransferase
JKA73_RS31150	COG0583	DNA-binding transcription factor activity
JKA73_RS31185	COG3387	PFAM Glycoside hydrolase 15-related
JKA73_RS31190	COG1063	alcohol dehydrogenase
JKA73_RS31195	COG0667	Aldo Keto reductase
JKA73_RS31230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JKA73_RS31245	COG0004	ammonium transporteR
JKA73_RS31255	COG0515	serine threonine protein kinase
JKA73_RS31280	COG1760	l-serine dehydratase
JKA73_RS31290	COG0693	protein deglycase activity
JKA73_RS31290	COG0753	catalase activity
JKA73_RS31315	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JKA73_RS31325	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS31335	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JKA73_RS31340	COG3938	Belongs to the proline racemase family
JKA73_RS31345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JKA73_RS31360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JKA73_RS31370	COG3291	Pkd domain containing protein
JKA73_RS31400	COG0300	oxidoreductase activity
JKA73_RS31440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JKA73_RS31445	COG4221	oxidoreductase activity
JKA73_RS31450	COG5002	protein histidine kinase activity
JKA73_RS31455	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JKA73_RS31510	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JKA73_RS31545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS31550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS31560	COG1309	transcriptional regulator
JKA73_RS31620	COG1509	lysine 2,3-aminomutase activity
JKA73_RS31660	COG0640	Transcriptional regulator
JKA73_RS31695	COG2342	PFAM TM1410 hypothetical-related protein
JKA73_RS31735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JKA73_RS31740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JKA73_RS31745	COG0469	pyruvate kinase activity
JKA73_RS31775	COG0517	IMP dehydrogenase activity
JKA73_RS31775	COG1994	Peptidase M50
JKA73_RS31800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JKA73_RS31810	COG0515	serine threonine protein kinase
JKA73_RS31820	COG3394	polysaccharide catabolic process
JKA73_RS31825	COG2205	protein histidine kinase activity
JKA73_RS31830	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JKA73_RS31835	COG0515	serine threonine protein kinase
JKA73_RS31835	COG2815	serine threonine protein kinase
JKA73_RS31845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JKA73_RS31865	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JKA73_RS31870	COG0300	oxidoreductase activity
JKA73_RS31925	COG0473	3-isopropylmalate dehydrogenase activity
JKA73_RS31930	COG0023	Translation Initiation Factor
JKA73_RS31935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JKA73_RS31945	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JKA73_RS31955	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JKA73_RS31975	COG0625	glutathione transferase activity
JKA73_RS32010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JKA73_RS32015	COG0277	FAD linked oxidase domain protein
JKA73_RS32075	COG1309	transcriptional regulator
JKA73_RS32080	COG0741	lytic transglycosylase activity
JKA73_RS32085	COG0363	glucosamine-6-phosphate deaminase activity
JKA73_RS32100	COG0318	PFAM AMP-dependent synthetase and ligase
JKA73_RS32115	COG1408	metallophosphoesterase
JKA73_RS32120	COG0235	Class ii aldolase
JKA73_RS32125	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JKA73_RS32130	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JKA73_RS32170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKA73_RS32175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JKA73_RS32180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKA73_RS32195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JKA73_RS32200	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS32205	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS32210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JKA73_RS32215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JKA73_RS32220	COG1136	(ABC) transporter
JKA73_RS32220	COG0577	efflux transmembrane transporter activity
JKA73_RS32285	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JKA73_RS32325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JKA73_RS32355	COG2815	serine threonine protein kinase
JKA73_RS32355	COG0515	serine threonine protein kinase
JKA73_RS32365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JKA73_RS32370	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS32385	COG4783	chaperone-mediated protein folding
JKA73_RS32405	COG0740	serine-type endopeptidase activity
JKA73_RS32410	COG0114	fumarate hydratase activity
JKA73_RS32420	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JKA73_RS32425	COG2224	Isocitrate lyase
JKA73_RS32500	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JKA73_RS32515	COG2094	Belongs to the DNA glycosylase MPG family
JKA73_RS32520	COG1640	4-alpha-glucanotransferase
JKA73_RS32545	COG0583	DNA-binding transcription factor activity
JKA73_RS32585	COG1131	(ABC) transporter
JKA73_RS32595	COG0714	Associated with various cellular activities
JKA73_RS32620	COG0667	Aldo Keto reductase
JKA73_RS32705	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JKA73_RS32710	COG1940	carbohydrate kinase activity
JKA73_RS32760	COG3119	arylsulfatase activity
JKA73_RS32775	COG3795	YCII-related domain
JKA73_RS32795	COG1968	undecaprenyl-diphosphatase activity
JKA73_RS32805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JKA73_RS32810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JKA73_RS32835	COG1285	pathogenesis
JKA73_RS32840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JKA73_RS32845	COG0523	cobalamin synthesis protein
JKA73_RS32855	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JKA73_RS32865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JKA73_RS32875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JKA73_RS32885	COG3716	PTS system mannose fructose sorbose family IID component
JKA73_RS32895	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKA73_RS32900	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKA73_RS32900	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKA73_RS32905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JKA73_RS32950	COG4771	TonB-dependent receptor
JKA73_RS32975	COG0601	transmembrane transport
JKA73_RS32980	COG0444	Belongs to the ABC transporter superfamily
JKA73_RS33040	COG1660	Displays ATPase and GTPase activities
JKA73_RS33045	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JKA73_RS33050	COG0537	adenosine 5'-monophosphoramidase activity
JKA73_RS33065	COG1120	ATPase activity
JKA73_RS33070	COG0515	serine threonine protein kinase
JKA73_RS33080	COG0723	plastoquinol--plastocyanin reductase activity
JKA73_RS33080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JKA73_RS33095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKA73_RS33110	COG4206	TonB-dependent receptor
JKA73_RS33150	COG2205	protein histidine kinase activity
JKA73_RS33150	COG3437	response regulator, receiver
JKA73_RS33150	COG4999	Histidine kinase
JKA73_RS33150	COG3850	Histidine kinase
JKA73_RS33170	COG1846	Transcriptional regulator
JKA73_RS33200	COG1506	peptidase
JKA73_RS33200	COG0823	Involved in the tonB-independent uptake of proteins
JKA73_RS33205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JKA73_RS33215	COG0443	Heat shock 70 kDa protein
JKA73_RS33225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JKA73_RS33230	COG1024	Enoyl-CoA hydratase
JKA73_RS33240	COG0714	Associated with various cellular activities
JKA73_RS33275	COG0513	Belongs to the DEAD box helicase family
JKA73_RS33285	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JKA73_RS33290	COG0745	RESPONSE REGULATOR receiver
JKA73_RS33295	COG1472	Belongs to the glycosyl hydrolase 3 family
JKA73_RS33305	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JKA73_RS33320	COG0745	RESPONSE REGULATOR receiver
JKA73_RS33335	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JKA73_RS33335	COG0546	phosphoglycolate phosphatase activity
JKA73_RS33340	COG0277	FAD linked oxidase domain protein
JKA73_RS33365	COG0318	PFAM AMP-dependent synthetase and ligase
JKA73_RS33370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKA73_RS33375	COG1755	Isoprenylcysteine carboxyl methyltransferase
JKA73_RS33395	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JKA73_RS33400	COG4149	molybdate abc transporter
JKA73_RS33405	COG0725	ABC transporter, periplasmic molybdate-binding protein
JKA73_RS33410	COG1846	Transcriptional regulator
JKA73_RS33415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKA73_RS33420	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JKA73_RS33460	COG0442	prolyl-tRNA aminoacylation
JKA73_RS33465	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JKA73_RS33480	COG4106	trans-aconitate 2-methyltransferase activity
JKA73_RS33515	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
JKA73_RS33540	COG0443	Heat shock 70 kDa protein
JKA73_RS33545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JKA73_RS33595	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JKA73_RS33600	COG1691	(AIR) carboxylase
JKA73_RS33610	COG2198	Histidine kinase
JKA73_RS33610	COG0643	Histidine kinase
JKA73_RS33615	COG2201	protein-glutamate methylesterase activity
JKA73_RS33620	COG0835	chemotaxis
JKA73_RS33635	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JKA73_RS33660	COG5002	protein histidine kinase activity
JKA73_RS33660	COG0784	Response regulator, receiver
JKA73_RS33660	COG2205	protein histidine kinase activity
JKA73_RS33665	COG1100	Small GTP-binding protein
JKA73_RS33670	COG0456	acetyltransferase
JKA73_RS33690	COG2137	regulation of response to DNA damage stimulus
JKA73_RS33720	COG0024	Methionine aminopeptidase
JKA73_RS33730	COG4206	TonB-dependent receptor
JKA73_RS33735	COG1199	ATP-dependent helicase activity
JKA73_RS33760	COG0546	phosphoglycolate phosphatase activity
JKA73_RS33770	COG1597	lipid kinase activity
JKA73_RS33780	COG1420	regulation of RNA biosynthetic process
JKA73_RS33785	COG0697	spore germination
JKA73_RS33800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JKA73_RS33805	COG0235	Class ii aldolase
JKA73_RS33810	COG2205	protein histidine kinase activity
JKA73_RS33810	COG2202	Pas domain
JKA73_RS33815	COG2205	protein histidine kinase activity
JKA73_RS33815	COG0784	Response regulator, receiver
JKA73_RS33815	COG5002	protein histidine kinase activity
JKA73_RS33865	COG2133	pyrroloquinoline quinone binding
JKA73_RS33870	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS33945	COG0408	coproporphyrinogen oxidase activity
JKA73_RS33960	COG2267	carboxylic ester hydrolase activity
JKA73_RS33970	COG0577	efflux transmembrane transporter activity
JKA73_RS33995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JKA73_RS34005	COG2154	pterin-4-alpha-carbinolamine dehydratase
JKA73_RS34025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JKA73_RS34035	COG2171	N-acyltransferase activity
JKA73_RS34055	COG0076	glutamate decarboxylase activity
JKA73_RS34065	COG4651	solute:proton antiporter activity
JKA73_RS34065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JKA73_RS34085	COG1077	Cell shape determining protein MreB Mrl
JKA73_RS34100	COG0583	DNA-binding transcription factor activity
JKA73_RS34110	COG2155	Conserved Protein
JKA73_RS34120	COG3781	membrane
JKA73_RS34150	COG0574	Belongs to the PEP-utilizing enzyme family
JKA73_RS34150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JKA73_RS34155	COG1063	alcohol dehydrogenase
JKA73_RS34160	COG0534	Mate efflux family protein
JKA73_RS34180	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JKA73_RS34200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JKA73_RS34215	COG1505	serine-type exopeptidase activity
JKA73_RS34230	COG3594	Acyltransferase
JKA73_RS34245	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JKA73_RS34245	COG0392	lysyltransferase activity
JKA73_RS34265	COG0308	aminopeptidase N
JKA73_RS34285	COG1668	transmembrane transport
JKA73_RS34290	COG4555	ABC transporter
JKA73_RS34305	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JKA73_RS34330	COG3568	Endonuclease Exonuclease Phosphatase
JKA73_RS34330	COG1555	photosystem II stabilization
JKA73_RS34360	COG0477	Major facilitator Superfamily
JKA73_RS34390	COG5002	protein histidine kinase activity
JKA73_RS34395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKA73_RS34410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JKA73_RS34410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JKA73_RS34470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JKA73_RS34475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JKA73_RS34475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JKA73_RS34495	COG0720	synthase
JKA73_RS34500	COG4221	oxidoreductase activity
JKA73_RS34535	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS34550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JKA73_RS34600	COG1160	GTP binding
JKA73_RS34620	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS34630	COG3047	cAMP biosynthetic process
JKA73_RS34630	COG2885	chlorophyll binding
JKA73_RS34680	COG0166	Belongs to the GPI family
JKA73_RS34685	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS34695	COG4771	TonB-dependent receptor
JKA73_RS34705	COG1271	oxidase subunit
JKA73_RS34730	COG1959	2 iron, 2 sulfur cluster binding
JKA73_RS34740	COG2346	COG2346, Truncated hemoglobins
JKA73_RS34745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JKA73_RS34755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JKA73_RS34760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JKA73_RS34765	COG0784	Response regulator, receiver
JKA73_RS34765	COG0835	chemotaxis
JKA73_RS34770	COG2949	membrane
JKA73_RS34785	COG3118	belongs to the thioredoxin family
JKA73_RS34835	COG2205	protein histidine kinase activity
JKA73_RS34835	COG5002	protein histidine kinase activity
JKA73_RS34835	COG0784	Response regulator, receiver
JKA73_RS34860	COG0835	chemotaxis
JKA73_RS34875	COG0840	transmembrane signaling receptor activity
JKA73_RS34885	COG2201	protein-glutamate methylesterase activity
JKA73_RS34890	COG5002	protein histidine kinase activity
JKA73_RS34900	COG5002	protein histidine kinase activity
JKA73_RS34905	COG0745	RESPONSE REGULATOR receiver
JKA73_RS34920	COG2201	protein-glutamate methylesterase activity
JKA73_RS34940	COG0835	chemotaxis
JKA73_RS34945	COG0643	Histidine kinase
JKA73_RS34945	COG2198	Histidine kinase
JKA73_RS34955	COG5002	protein histidine kinase activity
JKA73_RS34965	COG0745	RESPONSE REGULATOR receiver
JKA73_RS34980	COG0784	Response regulator, receiver
JKA73_RS34980	COG2205	protein histidine kinase activity
JKA73_RS34980	COG5002	protein histidine kinase activity
JKA73_RS34985	COG1408	metallophosphoesterase
JKA73_RS35020	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JKA73_RS35030	COG2226	methyltransferase
JKA73_RS35035	COG0789	Transcriptional regulator
JKA73_RS35055	COG1012	belongs to the aldehyde dehydrogenase family
JKA73_RS35065	COG0183	Belongs to the thiolase family
JKA73_RS35085	COG5002	protein histidine kinase activity
JKA73_RS35120	COG0745	RESPONSE REGULATOR receiver
JKA73_RS35130	COG5002	protein histidine kinase activity
JKA73_RS35185	COG1518	maintenance of DNA repeat elements
JKA73_RS35220	COG0534	Mate efflux family protein
JKA73_RS35235	COG0443	Heat shock 70 kDa protein
JKA73_RS35240	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JKA73_RS35275	COG2204	response regulator
JKA73_RS35285	COG0746	molybdenum cofactor guanylyltransferase activity
JKA73_RS35305	COG2267	carboxylic ester hydrolase activity
JKA73_RS35315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKA73_RS35315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKA73_RS35325	COG0667	Aldo Keto reductase
JKA73_RS35390	COG2270	Major facilitator Superfamily
JKA73_RS35405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JKA73_RS35415	COG0217	transcriptional regulatory protein
JKA73_RS35445	COG1733	regulation of RNA biosynthetic process
JKA73_RS35455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JKA73_RS35475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JKA73_RS35525	COG2815	serine threonine protein kinase
JKA73_RS35525	COG0515	serine threonine protein kinase
JKA73_RS35565	COG0386	Belongs to the glutathione peroxidase family
JKA73_RS35585	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JKA73_RS35655	COG0412	Dienelactone hydrolase
JKA73_RS35660	COG0545	Peptidyl-prolyl cis-trans isomerase
JKA73_RS35685	COG4149	molybdate abc transporter
JKA73_RS35705	COG0534	Mate efflux family protein
JKA73_RS35725	COG0642	Histidine kinase
JKA73_RS35725	COG3850	Histidine kinase
JKA73_RS35810	COG1058	Belongs to the CinA family
JKA73_RS35810	COG1546	Belongs to the CinA family
JKA73_RS35815	COG0768	penicillin binding
JKA73_RS35830	COG3852	Histidine kinase
JKA73_RS35840	COG1136	(ABC) transporter
JKA73_RS35840	COG0577	efflux transmembrane transporter activity
JKA73_RS35845	COG1136	(ABC) transporter
JKA73_RS35850	COG0577	efflux transmembrane transporter activity
JKA73_RS35850	COG1136	(ABC) transporter
JKA73_RS35860	COG0318	PFAM AMP-dependent synthetase and ligase
JKA73_RS35865	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JKA73_RS35875	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JKA73_RS35895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JKA73_RS35900	COG1024	Enoyl-CoA hydratase
JKA73_RS35905	COG0308	aminopeptidase N
JKA73_RS35910	COG1560	Kdo2-lipid A biosynthetic process
JKA73_RS35925	COG0515	serine threonine protein kinase
JKA73_RS35925	COG2815	serine threonine protein kinase
JKA73_RS35930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JKA73_RS35940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JKA73_RS35970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JKA73_RS35990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JKA73_RS36000	COG0745	RESPONSE REGULATOR receiver
JKA73_RS36010	COG2205	protein histidine kinase activity
JKA73_RS36040	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS36045	COG0438	transferase activity, transferring glycosyl groups
JKA73_RS36070	COG1056	cytidyltransferase-related domain
JKA73_RS36070	COG1051	belongs to the nudix hydrolase family
JKA73_RS36080	COG1028	Short-chain dehydrogenase reductase Sdr
JKA73_RS36145	COG0515	serine threonine protein kinase
JKA73_RS36150	COG1404	Belongs to the peptidase S8 family
JKA73_RS36150	COG1404	Belongs to the peptidase S8 family
JKA73_RS36225	COG3842	ATPase activity
JKA73_RS36230	COG1127	ABC transporter
JKA73_RS36255	COG0596	Alpha beta hydrolase
JKA73_RS36300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JKA73_RS36350	COG0515	serine threonine protein kinase
JKA73_RS36355	COG3932	Exopolysaccharide synthesis, ExoD
JKA73_RS36365	COG0702	epimerase
JKA73_RS36395	COG0515	serine threonine protein kinase
JKA73_RS36445	COG1653	transport
JKA73_RS36475	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JKA73_RS36490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JKA73_RS36490	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JKA73_RS36515	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JKA73_RS36530	COG1960	acyl-CoA dehydrogenase activity
JKA73_RS36535	COG0583	DNA-binding transcription factor activity
JKA73_RS36555	COG1309	transcriptional regulator
JKA73_RS36600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JKA73_RS36615	COG1064	alcohol dehydrogenase
JKA73_RS36625	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JKA73_RS36625	COG2755	lipolytic protein G-D-S-L family
JKA73_RS36645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JKA73_RS36730	COG0242	peptide deformylase activity
JKA73_RS36760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JKA73_RS36780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JKA73_RS36795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JKA73_RS36815	COG5002	protein histidine kinase activity
JKA73_RS36820	COG0745	RESPONSE REGULATOR receiver
JKA73_RS36835	COG5001	Diguanylate cyclase
JKA73_RS36850	COG2815	serine threonine protein kinase
JKA73_RS36850	COG0515	serine threonine protein kinase
JKA73_RS36875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JKA73_RS36885	COG0003	Pfam Anion-transporting ATPase
JKA73_RS36890	COG0517	IMP dehydrogenase activity
JKA73_RS36890	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JKA73_RS36925	COG3942	CHAP domain
JKA73_RS36925	COG1388	LysM domain
JKA73_RS36950	COG3829	transcription factor binding
JKA73_RS36950	COG3290	protein histidine kinase activity
JKA73_RS36985	COG3483	tryptophan 2,3-dioxygenase activity
JKA73_RS37005	COG0506	proline dehydrogenase activity
JKA73_RS37010	COG3387	PFAM Glycoside hydrolase 15-related
JKA73_RS37025	COG2814	Major facilitator Superfamily
JKA73_RS37040	COG0746	molybdenum cofactor guanylyltransferase activity
JKA73_RS37045	COG0303	'Molybdopterin
JKA73_RS37055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JKA73_RS37080	COG0745	RESPONSE REGULATOR receiver
JKA73_RS37100	COG2304	oxidoreductase activity
JKA73_RS37135	COG2205	protein histidine kinase activity
JKA73_RS37155	COG2239	Acts as a magnesium transporter
JKA73_RS37160	COG5002	protein histidine kinase activity
JKA73_RS37180	COG1045	serine acetyltransferase
JKA73_RS37265	COG0038	chloride channel
JKA73_RS37290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JKA73_RS37295	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JKA73_RS37315	COG1475	DNA binding
JKA73_RS37320	COG1192	Involved in chromosome partitioning
JKA73_RS37335	COG0357	Ribosomal RNA small subunit methyltransferase G
JKA73_RS37340	COG0445	tRNA wobble uridine modification
JKA73_RS37345	COG2814	Major facilitator Superfamily
JKA73_RS37350	COG2267	carboxylic ester hydrolase activity
JKA73_RS37360	COG0612	Peptidase, M16
JKA73_RS37365	COG0616	signal peptide processing
JKA73_RS37380	COG0640	Transcriptional regulator
JKA73_RS37385	COG3832	glyoxalase III activity
JKA73_RS37400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JKA73_RS37415	COG0706	membrane insertase activity
JKA73_RS37420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JKA73_RS37425	COG0594	ribonuclease P activity
JKA73_RS37430	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JKA73_RS37440	COG0515	serine threonine protein kinase
JKA73_RS37440	COG3064	Membrane
JKA73_RS37440	COG4991	sh3 domain protein