locus-tag	class	description
C3L23_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C3L23_RS00010	COG0592	DNA-directed DNA polymerase activity
C3L23_RS00015	COG0187	DNA topoisomerase II activity
C3L23_RS00020	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C3L23_RS00025	COG1459	type II secretion system
C3L23_RS00030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C3L23_RS00080	COG2165	general secretion pathway protein
C3L23_RS00110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C3L23_RS00110	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C3L23_RS00135	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
C3L23_RS00140	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
C3L23_RS00160	COG1269	ATP hydrolysis coupled proton transport
C3L23_RS00175	COG0237	dephospho-CoA kinase activity
C3L23_RS00190	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C3L23_RS00195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C3L23_RS00200	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C3L23_RS00205	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C3L23_RS00210	COG1077	Cell shape determining protein MreB Mrl
C3L23_RS00225	COG3022	response to hydroperoxide
C3L23_RS00245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3L23_RS00255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C3L23_RS00260	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C3L23_RS00265	COG0352	thiamine-phosphate diphosphorylase activity
C3L23_RS00270	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C3L23_RS00285	COG0284	orotidine-5'-phosphate decarboxylase activity
C3L23_RS00290	COG0717	Belongs to the dCTP deaminase family
C3L23_RS00300	COG0511	ligase activity, forming carbon-carbon bonds
C3L23_RS00305	COG0439	Biotin carboxylase
C3L23_RS00315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3L23_RS00320	COG0668	transmembrane transport
C3L23_RS00330	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C3L23_RS00340	COG2814	Major facilitator Superfamily
C3L23_RS00350	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C3L23_RS00355	COG0233	cytoplasmic translational termination
C3L23_RS00365	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C3L23_RS00380	COG0352	thiamine-phosphate diphosphorylase activity
C3L23_RS00385	COG0670	Belongs to the BI1 family
C3L23_RS00395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C3L23_RS00410	COG0840	transmembrane signaling receptor activity
C3L23_RS00425	COG2022	thiamine diphosphate biosynthetic process
C3L23_RS00435	COG3706	GGDEF domain
C3L23_RS00470	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C3L23_RS00480	COG1294	oxidase, subunit
C3L23_RS00500	COG0328	RNA-DNA hybrid ribonuclease activity
C3L23_RS00510	COG0571	ribonuclease III activity
C3L23_RS00515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C3L23_RS00520	COG1917	Cupin 2, conserved barrel domain protein
C3L23_RS00535	COG0314	molybdopterin synthase activity
C3L23_RS00560	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C3L23_RS00565	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C3L23_RS00570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C3L23_RS00580	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C3L23_RS00595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C3L23_RS00600	COG0531	amino acid
C3L23_RS00615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C3L23_RS00620	COG1984	allophanate hydrolase subunit 2
C3L23_RS00625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C3L23_RS00630	COG0156	8-amino-7-oxononanoate synthase activity
C3L23_RS00635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C3L23_RS00640	COG0745	RESPONSE REGULATOR receiver
C3L23_RS00645	COG0642	Histidine kinase
C3L23_RS00650	COG0424	maF-like protein
C3L23_RS00660	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C3L23_RS00665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C3L23_RS00670	COG0745	RESPONSE REGULATOR receiver
C3L23_RS00675	COG2264	protein methyltransferase activity
C3L23_RS00680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3L23_RS00690	COG1183	phosphatidylcholine synthase activity
C3L23_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C3L23_RS00700	COG1160	GTP binding
C3L23_RS00710	COG0180	Tryptophanyl-tRNA synthetase
C3L23_RS00720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C3L23_RS00725	COG0688	phosphatidylethanolamine metabolic process
C3L23_RS00745	COG0505	Belongs to the CarA family
C3L23_RS00755	COG1968	undecaprenyl-diphosphatase activity
C3L23_RS00760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C3L23_RS00770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C3L23_RS00775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C3L23_RS00840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C3L23_RS00845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C3L23_RS00865	COG0250	Participates in transcription elongation, termination and antitermination
C3L23_RS00870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C3L23_RS00875	COG0081	regulation of translation
C3L23_RS00880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C3L23_RS00885	COG0222	ribosome binding
C3L23_RS00890	COG0085	RNA polymerase activity
C3L23_RS00890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C3L23_RS00895	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C3L23_RS00900	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C3L23_RS00905	COG0049	tRNA binding
C3L23_RS00910	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C3L23_RS00925	COG0157	Belongs to the NadC ModD family
C3L23_RS00945	COG3681	Belongs to the UPF0597 family
C3L23_RS00950	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C3L23_RS00985	COG4662	Binding-protein-dependent transport system inner membrane component
C3L23_RS01005	COG0157	Belongs to the NadC ModD family
C3L23_RS01010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C3L23_RS01015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C3L23_RS01025	COG0745	RESPONSE REGULATOR receiver
C3L23_RS01030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C3L23_RS01035	COG0248	Ppx GppA phosphatase
C3L23_RS01080	COG0004	ammonium transporteR
C3L23_RS01085	COG0347	Belongs to the P(II) protein family
C3L23_RS01125	COG1748	Saccharopine dehydrogenase
C3L23_RS01135	COG3290	protein histidine kinase activity
C3L23_RS01135	COG0840	transmembrane signaling receptor activity
C3L23_RS01145	COG3706	GGDEF domain
C3L23_RS01150	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C3L23_RS01155	COG0135	phosphoribosylanthranilate isomerase activity
C3L23_RS01160	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C3L23_RS01170	COG0575	Belongs to the CDS family
C3L23_RS01175	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C3L23_RS01180	COG0546	phosphoglycolate phosphatase activity
C3L23_RS01185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3L23_RS01190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3L23_RS01195	COG0569	domain protein
C3L23_RS01200	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C3L23_RS01205	COG1144	Oxidoreductase
C3L23_RS01210	COG0674	pyruvate-flavodoxin oxidoreductase activity
C3L23_RS01215	COG1013	pyruvate-flavodoxin oxidoreductase activity
C3L23_RS01220	COG0038	chloride channel
C3L23_RS01240	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C3L23_RS01245	COG2201	protein-glutamate methylesterase activity
C3L23_RS01250	COG0598	Magnesium transport protein CorA
C3L23_RS01260	COG2194	sulfuric ester hydrolase activity
C3L23_RS01265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C3L23_RS01270	COG5002	protein histidine kinase activity
C3L23_RS01280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C3L23_RS01285	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C3L23_RS01290	COG0504	CTP synthase activity
C3L23_RS01295	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C3L23_RS01295	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C3L23_RS01310	COG1858	cytochrome C peroxidase
C3L23_RS01315	COG5001	Diguanylate cyclase
C3L23_RS01315	COG5002	protein histidine kinase activity
C3L23_RS01320	COG0792	nuclease activity
C3L23_RS01325	COG0824	Thioesterase
C3L23_RS01330	COG2081	HI0933 family
C3L23_RS01350	COG4974	Belongs to the 'phage' integrase family
C3L23_RS01370	COG0195	Participates in both transcription termination and antitermination
C3L23_RS01390	COG0038	chloride channel
C3L23_RS01395	COG1987	bacterial-type flagellum assembly
C3L23_RS01405	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
C3L23_RS01410	COG3287	FIST C domain
C3L23_RS01410	COG2199	diguanylate cyclase activity
C3L23_RS01410	COG2200	EAL domain
C3L23_RS01415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C3L23_RS01420	COG0148	phosphopyruvate hydratase activity
C3L23_RS01435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C3L23_RS01445	COG1573	uracil-dna glycosylase
C3L23_RS01455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C3L23_RS01465	COG2165	general secretion pathway protein
C3L23_RS01475	COG0616	signal peptide processing
C3L23_RS01480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C3L23_RS01490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3L23_RS01495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C3L23_RS01500	COG0825	malonyl-CoA metabolic process
C3L23_RS01515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C3L23_RS01530	COG0730	response to heat
C3L23_RS01540	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3L23_RS01540	COG1776	CheC inhibitor of MCP methylation
C3L23_RS01550	COG0445	tRNA wobble uridine modification
C3L23_RS01570	COG0745	RESPONSE REGULATOR receiver
C3L23_RS01580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C3L23_RS01590	COG0581	inorganic phosphate transmembrane transporter activity
C3L23_RS01595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C3L23_RS01600	COG0306	phosphate transporter
C3L23_RS01605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C3L23_RS01615	COG1192	Involved in chromosome partitioning
C3L23_RS01620	COG1475	DNA binding
C3L23_RS01630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C3L23_RS01635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C3L23_RS01640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C3L23_RS01645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C3L23_RS01650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C3L23_RS01655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C3L23_RS01660	COG0811	peptide transport
C3L23_RS01665	COG0848	biopolymer transport protein
C3L23_RS01675	COG0823	Involved in the tonB-independent uptake of proteins
C3L23_RS01680	COG3047	cAMP biosynthetic process
C3L23_RS01680	COG2885	chlorophyll binding
C3L23_RS01690	COG1047	Peptidyl-prolyl cis-trans
C3L23_RS01695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C3L23_RS01705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C3L23_RS01715	COG0037	tRNA processing
C3L23_RS01720	COG0482	sulfurtransferase activity
C3L23_RS01725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C3L23_RS01730	COG1739	Uncharacterized protein family UPF0029
C3L23_RS01740	COG0531	amino acid
C3L23_RS01745	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C3L23_RS01750	COG2046	Belongs to the sulfate adenylyltransferase family
C3L23_RS01760	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C3L23_RS01760	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C3L23_RS01770	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C3L23_RS01775	COG0489	protein tyrosine kinase activity
C3L23_RS01795	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C3L23_RS01805	COG1074	ATP-dependent DNA helicase activity
C3L23_RS01820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C3L23_RS01825	COG0756	dUTP diphosphatase activity
C3L23_RS01830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C3L23_RS01840	COG0835	chemotaxis
C3L23_RS01840	COG0784	Response regulator, receiver
C3L23_RS01845	COG0643	Histidine kinase
C3L23_RS01845	COG0784	Response regulator, receiver
C3L23_RS01845	COG2198	Histidine kinase
C3L23_RS01850	COG0835	chemotaxis
C3L23_RS01855	COG1166	arginine decarboxylase activity
C3L23_RS01860	COG0124	histidyl-tRNA synthetase
C3L23_RS01870	COG1692	metallophosphoesterase
C3L23_RS01880	COG1451	nucleotide metabolic process
C3L23_RS01885	COG1322	Protein conserved in bacteria
C3L23_RS01910	COG0315	cyclic pyranopterin monophosphate synthase activity
C3L23_RS01920	COG0730	response to heat
C3L23_RS01930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3L23_RS01945	COG1309	transcriptional regulator
C3L23_RS01955	COG2833	Protein of unknown function (DUF455)
C3L23_RS01960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C3L23_RS01965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C3L23_RS01980	COG0745	RESPONSE REGULATOR receiver
C3L23_RS01985	COG0642	Histidine kinase
C3L23_RS02005	COG0004	ammonium transporteR
C3L23_RS02010	COG0347	Belongs to the P(II) protein family
C3L23_RS02020	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C3L23_RS02030	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C3L23_RS02035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3L23_RS02045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3L23_RS02050	COG0432	Pfam Uncharacterised protein family UPF0047
C3L23_RS02065	COG0179	Fumarylacetoacetate (FAA) hydrolase
C3L23_RS02070	COG0602	queuosine metabolic process
C3L23_RS02080	COG1851	Uncharacterised protein family (UPF0128)
C3L23_RS02085	COG1332	CRISPR-associated RAMP protein, Csm5 family
C3L23_RS02175	COG0582	viral genome integration into host DNA
C3L23_RS02185	COG2095	MarC family integral membrane protein
C3L23_RS02195	COG3264	Mechanosensitive ion channel
C3L23_RS02195	COG1196	nuclear chromosome segregation
C3L23_RS02210	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C3L23_RS02215	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C3L23_RS02225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3L23_RS02230	COG0416	fatty acid biosynthetic process
C3L23_RS02235	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C3L23_RS02245	COG0105	UTP biosynthetic process
C3L23_RS02290	COG2304	oxidoreductase activity
C3L23_RS02305	COG0714	Associated with various cellular activities
C3L23_RS02320	COG0840	transmembrane signaling receptor activity
C3L23_RS02340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3L23_RS02345	COG1331	Highly conserved protein containing a thioredoxin domain
C3L23_RS02350	COG2033	superoxide reductase activity
C3L23_RS02355	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C3L23_RS02365	COG0052	Belongs to the universal ribosomal protein uS2 family
C3L23_RS02370	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C3L23_RS02375	COG1136	(ABC) transporter
C3L23_RS02375	COG0577	efflux transmembrane transporter activity
C3L23_RS02380	COG1684	flagellar biosynthetic protein fliR
C3L23_RS02395	COG0194	GDP metabolic process
C3L23_RS02400	COG0018	arginyl-trna synthetase
C3L23_RS02425	COG0799	negative regulation of ribosome biogenesis
C3L23_RS02430	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C3L23_RS02435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3L23_RS02440	COG0126	phosphoglycerate kinase activity
C3L23_RS02445	COG0149	triose-phosphate isomerase activity
C3L23_RS02450	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C3L23_RS02455	COG4773	Receptor
C3L23_RS02465	COG0460	homoserine dehydrogenase
C3L23_RS02470	COG0436	Aminotransferase
C3L23_RS02490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C3L23_RS02495	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C3L23_RS02505	COG1573	uracil-dna glycosylase
C3L23_RS02515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C3L23_RS02525	COG0343	queuine tRNA-ribosyltransferase activity
C3L23_RS02555	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C3L23_RS02580	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C3L23_RS02585	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C3L23_RS02590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C3L23_RS02620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3L23_RS02625	COG0174	glutamine synthetase
C3L23_RS02640	COG0540	Belongs to the ATCase OTCase family
C3L23_RS02645	COG0500	methyltransferase
C3L23_RS02655	COG2195	Cleaves the N-terminal amino acid of tripeptides
C3L23_RS02660	COG0288	reversible hydration of carbon dioxide
C3L23_RS02675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C3L23_RS02680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C3L23_RS02685	COG1758	RNA polymerase activity
C3L23_RS02695	COG0564	pseudouridine synthase activity
C3L23_RS02705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C3L23_RS02725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C3L23_RS02730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C3L23_RS02735	COG2161	toxin-antitoxin pair type II binding
C3L23_RS02740	COG4115	mRNA cleavage
C3L23_RS02780	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C3L23_RS02800	COG0772	Belongs to the SEDS family
C3L23_RS02805	COG0840	transmembrane signaling receptor activity
C3L23_RS02810	COG0840	transmembrane signaling receptor activity
C3L23_RS02825	COG0357	Ribosomal RNA small subunit methyltransferase G
C3L23_RS02830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C3L23_RS02835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C3L23_RS02880	COG3043	anaerobic respiration
C3L23_RS02885	COG0348	domain, Protein
C3L23_RS02890	COG0437	4 iron, 4 sulfur cluster binding
C3L23_RS02895	COG0243	molybdopterin cofactor binding
C3L23_RS02900	COG0745	RESPONSE REGULATOR receiver
C3L23_RS02920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C3L23_RS02920	COG1333	cytochrome c biogenesis protein
C3L23_RS02925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C3L23_RS02930	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C3L23_RS02935	COG0113	porphobilinogen synthase activity
C3L23_RS02940	COG0181	hydroxymethylbilane synthase activity
C3L23_RS02945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3L23_RS02955	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C3L23_RS02960	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C3L23_RS02980	COG0375	protein maturation
C3L23_RS03000	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C3L23_RS03005	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C3L23_RS03010	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C3L23_RS03015	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C3L23_RS03020	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C3L23_RS03025	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C3L23_RS03045	COG0765	amino acid transport
C3L23_RS03060	COG0765	amino acid transport
C3L23_RS03070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3L23_RS03085	COG1127	ABC transporter
C3L23_RS03095	COG0840	transmembrane signaling receptor activity
C3L23_RS03105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3L23_RS03115	COG1473	amidohydrolase
C3L23_RS03130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C3L23_RS03135	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C3L23_RS03140	COG0542	response to heat
C3L23_RS03145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C3L23_RS03150	COG0166	Belongs to the GPI family
C3L23_RS03165	COG4786	Flagellar basal body rod
C3L23_RS03170	COG4786	Flagellar basal body rod
C3L23_RS03175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C3L23_RS03180	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C3L23_RS03185	COG1663	tetraacyldisaccharide 4'-kinase activity
C3L23_RS03210	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C3L23_RS03215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C3L23_RS03225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C3L23_RS03230	COG0217	transcriptional regulatory protein
C3L23_RS03235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3L23_RS03240	COG0191	fructose-bisphosphate aldolase activity
C3L23_RS03250	COG2111	Na H antiporter
C3L23_RS03250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3L23_RS03255	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C3L23_RS03270	COG3261	NADH dehydrogenase
C3L23_RS03270	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C3L23_RS03290	COG3290	protein histidine kinase activity
C3L23_RS03290	COG0840	transmembrane signaling receptor activity
C3L23_RS03345	COG0582	viral genome integration into host DNA
C3L23_RS03360	COG3228	Belongs to the MtfA family
C3L23_RS03365	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C3L23_RS03370	COG0204	Acyl-transferase
C3L23_RS03380	COG0739	heme binding
C3L23_RS03385	COG0047	phosphoribosylformylglycinamidine synthase activity
C3L23_RS03395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C3L23_RS03400	COG0793	Belongs to the peptidase S41A family
C3L23_RS03405	COG0542	response to heat
C3L23_RS03420	COG0840	transmembrane signaling receptor activity
C3L23_RS03425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C3L23_RS03455	COG1040	competence protein
C3L23_RS03470	COG2204	response regulator
C3L23_RS03475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C3L23_RS03485	COG0731	radical SAM domain protein
C3L23_RS03515	COG4221	oxidoreductase activity
C3L23_RS03535	COG0159	tryptophan synthase activity
C3L23_RS03540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C3L23_RS03545	COG2255	four-way junction helicase activity
C3L23_RS03550	COG0628	permease
C3L23_RS03555	COG1420	regulation of RNA biosynthetic process
C3L23_RS03560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C3L23_RS03565	COG0443	Heat shock 70 kDa protein
C3L23_RS03575	COG1490	D-aminoacyl-tRNA deacylase activity
C3L23_RS03580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C3L23_RS03585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C3L23_RS03585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C3L23_RS03590	COG1546	Belongs to the CinA family
C3L23_RS03590	COG1058	Belongs to the CinA family
C3L23_RS03595	COG2326	polyphosphate kinase activity
C3L23_RS03600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C3L23_RS03610	COG0154	amidase activity
C3L23_RS03615	COG0516	GMP reductase activity
C3L23_RS03615	COG0517	IMP dehydrogenase activity
C3L23_RS03630	COG0019	diaminopimelate decarboxylase activity
C3L23_RS03665	COG0512	Glutamine amidotransferase of anthranilate synthase
C3L23_RS03675	COG0045	succinate-CoA ligase (ADP-forming) activity
C3L23_RS03715	COG0501	Belongs to the peptidase M48B family
C3L23_RS03720	COG1028	Short-chain dehydrogenase reductase Sdr
C3L23_RS03725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3L23_RS03745	COG2095	MarC family integral membrane protein
C3L23_RS03750	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C3L23_RS03765	COG4139	cobalamin transport
C3L23_RS03770	COG1120	ATPase activity
C3L23_RS03775	COG0310	cobalt ion transport
C3L23_RS03790	COG1122	ATPase activity
C3L23_RS03795	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C3L23_RS03800	COG0298	carbon dioxide binding
C3L23_RS03805	COG0409	Hydrogenase expression formation protein
C3L23_RS03810	COG0309	Hydrogenase expression formation protein (HypE)
C3L23_RS03825	COG0751	glycine-tRNA ligase activity
C3L23_RS03845	COG2200	EAL domain
C3L23_RS03845	COG2199	diguanylate cyclase activity
C3L23_RS03845	COG3287	FIST C domain
C3L23_RS03855	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3L23_RS03860	COG0649	NAD binding
C3L23_RS03865	COG0651	ATP synthesis coupled electron transport
C3L23_RS03880	COG0651	ATP synthesis coupled electron transport
C3L23_RS03895	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C3L23_RS03900	COG0681	Belongs to the peptidase S26 family
C3L23_RS03905	COG1994	Peptidase M50
C3L23_RS03915	COG0484	heat shock protein binding
C3L23_RS03920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C3L23_RS03925	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C3L23_RS03930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C3L23_RS03930	COG0574	Belongs to the PEP-utilizing enzyme family
C3L23_RS03950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C3L23_RS03955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3L23_RS03960	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3L23_RS03965	COG0022	dehydrogenase e1 component
C3L23_RS03970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3L23_RS03975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C3L23_RS03985	COG0205	6-phosphofructokinase activity
C3L23_RS03990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C3L23_RS03995	COG0321	lipoyl(octanoyl) transferase activity
C3L23_RS04010	COG0583	DNA-binding transcription factor activity
C3L23_RS04040	COG0142	geranyltranstransferase activity
C3L23_RS04045	COG0590	tRNA wobble adenosine to inosine editing
C3L23_RS04050	COG1192	Involved in chromosome partitioning
C3L23_RS04065	COG0802	atpase or kinase
C3L23_RS04070	COG1137	ATPase activity
C3L23_RS04075	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C3L23_RS04080	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C3L23_RS04085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C3L23_RS04090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C3L23_RS04095	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C3L23_RS04120	COG3271	cysteine-type peptidase activity
C3L23_RS04120	COG2274	protein secretion by the type I secretion system
C3L23_RS04130	COG1342	Belongs to the UPF0251 family
C3L23_RS04135	COG1252	NADH dehydrogenase
C3L23_RS04145	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C3L23_RS04150	COG0492	ferredoxin-NADP+ reductase activity
C3L23_RS04155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C3L23_RS04165	COG0028	Belongs to the TPP enzyme family
C3L23_RS04170	COG0440	acetolactate synthase activity
C3L23_RS04175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C3L23_RS04200	COG1053	succinate dehydrogenase
C3L23_RS04210	COG0277	FAD linked oxidase domain protein
C3L23_RS04240	COG2326	polyphosphate kinase activity
C3L23_RS04250	COG1045	serine acetyltransferase
C3L23_RS04255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C3L23_RS04260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C3L23_RS04265	COG0163	prenyltransferase activity
C3L23_RS04275	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C3L23_RS04285	COG0525	valine-tRNA ligase activity
C3L23_RS04290	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C3L23_RS04315	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C3L23_RS04320	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C3L23_RS04325	COG0594	ribonuclease P activity
C3L23_RS04330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C3L23_RS04335	COG0706	membrane insertase activity
C3L23_RS04345	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C3L23_RS04360	COG1355	regulation of microtubule-based process
C3L23_RS04370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C3L23_RS04400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C3L23_RS04405	COG0484	heat shock protein binding
C3L23_RS04415	COG1185	polyribonucleotide nucleotidyltransferase activity
C3L23_RS04420	COG0436	Aminotransferase
C3L23_RS04435	COG1794	racemase activity, acting on amino acids and derivatives
C3L23_RS04440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C3L23_RS04445	COG0612	Peptidase, M16
C3L23_RS04455	COG0275	rRNA processing
C3L23_RS04470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C3L23_RS04485	COG0387	Pfam Sodium calcium exchanger
C3L23_RS04490	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C3L23_RS04495	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C3L23_RS04500	COG1944	ATP diphosphatase activity
C3L23_RS04505	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C3L23_RS04515	COG0588	phosphoglycerate mutase activity
C3L23_RS04535	COG0390	transport system, permease component
C3L23_RS04540	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C3L23_RS04550	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C3L23_RS04555	COG4191	Histidine kinase
C3L23_RS04560	COG1959	2 iron, 2 sulfur cluster binding
C3L23_RS04565	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C3L23_RS04570	COG2226	methyltransferase
C3L23_RS04580	COG3287	FIST C domain
C3L23_RS04580	COG2200	EAL domain
C3L23_RS04580	COG2199	diguanylate cyclase activity
C3L23_RS04585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C3L23_RS04600	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C3L23_RS04615	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C3L23_RS04620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C3L23_RS04635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C3L23_RS04645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C3L23_RS04650	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C3L23_RS04655	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C3L23_RS04660	COG0537	adenosine 5'-monophosphoramidase activity
C3L23_RS04665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C3L23_RS04670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3L23_RS04670	COG0072	phenylalanine-tRNA ligase activity
C3L23_RS04675	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C3L23_RS04680	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C3L23_RS04685	COG1185	polyribonucleotide nucleotidyltransferase activity
C3L23_RS04685	COG0539	negative regulation of cytoplasmic translation
C3L23_RS04695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C3L23_RS04700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C3L23_RS04705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C3L23_RS04710	COG0133	tryptophan synthase activity
C3L23_RS04725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C3L23_RS04730	COG0012	GTP binding
C3L23_RS04735	COG2996	Protein conserved in bacteria
C3L23_RS04745	COG2361	Protein of unknown function DUF86
C3L23_RS04765	COG3012	SEC-C Motif Domain Protein
C3L23_RS04795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C3L23_RS04800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3L23_RS04815	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C3L23_RS04840	COG2824	Alkylphosphonate utilization operon protein PhnA
C3L23_RS04865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C3L23_RS04870	COG1254	Belongs to the acylphosphatase family
C3L23_RS04875	COG1181	Belongs to the D-alanine--D-alanine ligase family
C3L23_RS04880	COG0632	four-way junction helicase activity
C3L23_RS04890	COG0728	peptidoglycan biosynthetic process
C3L23_RS04895	COG0215	cysteine-tRNA ligase activity
C3L23_RS04920	COG2885	chlorophyll binding
C3L23_RS04930	COG0167	dihydroorotate dehydrogenase activity
C3L23_RS04935	COG0446	pyridine nucleotide-disulphide oxidoreductase
C3L23_RS04950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C3L23_RS04955	COG0750	zinc metalloprotease
C3L23_RS04960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C3L23_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
C3L23_RS04970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C3L23_RS04980	COG0653	protein targeting
C3L23_RS04995	COG0501	Belongs to the peptidase M48B family
C3L23_RS05000	COG2211	Major facilitator Superfamily
C3L23_RS05005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3L23_RS05015	COG0849	cell division
C3L23_RS05025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C3L23_RS05035	COG0736	holo-[acyl-carrier-protein] synthase activity
C3L23_RS05050	COG1136	(ABC) transporter
C3L23_RS05085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C3L23_RS05085	COG0519	Catalyzes the synthesis of GMP from XMP
C3L23_RS05090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C3L23_RS05095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C3L23_RS05110	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C3L23_RS05130	COG4145	pantothenate transmembrane transporter activity
C3L23_RS05135	COG0322	excinuclease ABC activity
C3L23_RS05145	COG1881	PFAM PEBP family protein
C3L23_RS05155	COG0196	riboflavin kinase activity
C3L23_RS05170	COG2201	protein-glutamate methylesterase activity
C3L23_RS05175	COG0643	Histidine kinase
C3L23_RS05175	COG2198	Histidine kinase
C3L23_RS05180	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C3L23_RS05190	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C3L23_RS05195	COG0488	(ABC) transporter
C3L23_RS05205	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C3L23_RS05210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3L23_RS05225	COG1749	Flagellar hook protein flgE
C3L23_RS05225	COG1749	Flagellar hook protein flgE
C3L23_RS05230	COG0165	Argininosuccinate lyase
C3L23_RS05255	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C3L23_RS05265	COG1280	lysine exporter protein (LysE YggA)
C3L23_RS05270	COG0436	Aminotransferase
C3L23_RS05275	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C3L23_RS05290	COG0497	DNA recombination
C3L23_RS05295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C3L23_RS05300	COG2193	ferroxidase activity
C3L23_RS05310	COG0668	transmembrane transport
C3L23_RS05315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C3L23_RS05325	COG0563	adenylate kinase activity
C3L23_RS05335	COG2199	diguanylate cyclase activity
C3L23_RS05335	COG2203	Gaf domain
C3L23_RS05345	COG2048	Heterodisulfide reductase, subunit B
C3L23_RS05350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C3L23_RS05355	COG1053	succinate dehydrogenase
C3L23_RS05360	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C3L23_RS05360	COG0493	'glutamate synthase
C3L23_RS05365	COG0375	protein maturation
C3L23_RS05370	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C3L23_RS05380	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3L23_RS05390	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3L23_RS05395	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C3L23_RS05400	COG0651	ATP synthesis coupled electron transport
C3L23_RS05405	COG0840	transmembrane signaling receptor activity
C3L23_RS05420	COG0442	prolyl-tRNA aminoacylation
C3L23_RS05445	COG2003	Belongs to the UPF0758 family
C3L23_RS05450	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C3L23_RS05455	COG0137	argininosuccinate synthase activity
C3L23_RS05475	COG1110	DNA topoisomerase II activity
C3L23_RS05485	COG1151	hydroxylamine reductase activity
C3L23_RS05500	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C3L23_RS05515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C3L23_RS05530	COG0305	Participates in initiation and elongation during chromosome replication
C3L23_RS05545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C3L23_RS05555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C3L23_RS05565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3L23_RS05570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C3L23_RS05575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C3L23_RS05600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3L23_RS05605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C3L23_RS05615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3L23_RS05625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C3L23_RS05630	COG1605	Chorismate mutase
C3L23_RS05630	COG0077	Prephenate dehydratase
C3L23_RS05640	COG0019	diaminopimelate decarboxylase activity
C3L23_RS05650	COG0193	aminoacyl-tRNA hydrolase activity
C3L23_RS05655	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C3L23_RS05665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C3L23_RS05670	COG0560	Phosphoserine phosphatase
C3L23_RS05675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C3L23_RS05680	COG0805	protein transport
C3L23_RS05695	COG3706	GGDEF domain
C3L23_RS05705	COG0585	pseudouridine synthase activity
C3L23_RS05715	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C3L23_RS05725	COG0840	transmembrane signaling receptor activity
C3L23_RS05730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C3L23_RS05745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C3L23_RS05755	COG1053	succinate dehydrogenase
C3L23_RS05765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C3L23_RS05775	COG0659	secondary active sulfate transmembrane transporter activity
C3L23_RS05780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C3L23_RS05785	COG2165	general secretion pathway protein
C3L23_RS05795	COG2165	general secretion pathway protein
C3L23_RS05810	COG0556	nucleotide-excision repair
C3L23_RS05820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C3L23_RS05825	COG1193	negative regulation of DNA recombination
C3L23_RS05830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C3L23_RS05835	COG3118	belongs to the thioredoxin family
C3L23_RS05840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C3L23_RS05850	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C3L23_RS05855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C3L23_RS05865	COG1459	type II secretion system
C3L23_RS05885	COG2894	cell division
C3L23_RS05890	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C3L23_RS05900	COG0758	DNA mediated transformation
C3L23_RS05910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C3L23_RS05915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C3L23_RS05920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C3L23_RS05925	COG1338	Plays a role in the flagellum-specific transport system
C3L23_RS05935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C3L23_RS05940	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C3L23_RS05955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C3L23_RS05960	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C3L23_RS06100	COG0616	signal peptide processing
C3L23_RS06160	COG0305	Participates in initiation and elongation during chromosome replication
C3L23_RS06185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C3L23_RS06230	COG0582	viral genome integration into host DNA
C3L23_RS06260	COG0358	DNA primase activity
C3L23_RS06265	COG0482	sulfurtransferase activity
C3L23_RS06270	COG0768	penicillin binding
C3L23_RS06285	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C3L23_RS06300	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C3L23_RS06305	COG0131	Imidazoleglycerol-phosphate dehydratase
C3L23_RS06310	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C3L23_RS06320	COG0084	hydrolase, TatD family'
C3L23_RS06325	COG0281	malic enzyme
C3L23_RS06335	COG0521	Mo-molybdopterin cofactor biosynthetic process
C3L23_RS06350	COG0698	ribose 5-phosphate isomerase
C3L23_RS06355	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C3L23_RS06370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C3L23_RS06385	COG0527	aspartate kinase activity
C3L23_RS06390	COG0494	nUDIX hydrolase
C3L23_RS06395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3L23_RS06405	COG0134	indole-3-glycerol-phosphate synthase activity
C3L23_RS06415	COG0727	PFAM Uncharacterised protein family (UPF0153)
C3L23_RS06430	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C3L23_RS06435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C3L23_RS06450	COG3962	Belongs to the TPP enzyme family
C3L23_RS06455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C3L23_RS06455	COG0674	pyruvate-flavodoxin oxidoreductase activity
C3L23_RS06465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C3L23_RS06470	COG0045	succinate-CoA ligase (ADP-forming) activity
C3L23_RS06475	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C3L23_RS06475	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C3L23_RS06485	COG0039	L-malate dehydrogenase activity
C3L23_RS06505	COG0789	Transcriptional regulator
C3L23_RS06510	COG0484	heat shock protein binding
C3L23_RS06520	COG0494	nUDIX hydrolase
C3L23_RS06530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3L23_RS06530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3L23_RS06535	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C3L23_RS06545	COG3174	membrane
C3L23_RS06550	COG0066	3-isopropylmalate dehydratase activity
C3L23_RS06555	COG0473	3-isopropylmalate dehydrogenase activity
C3L23_RS06575	COG0788	formyltetrahydrofolate deformylase activity
C3L23_RS06585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C3L23_RS06610	COG0557	exoribonuclease II activity
C3L23_RS06635	COG1074	ATP-dependent DNA helicase activity
C3L23_RS06655	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C3L23_RS06660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C3L23_RS06665	COG0359	binds to the 23S rRNA
C3L23_RS06670	COG0840	transmembrane signaling receptor activity
C3L23_RS06685	COG3437	response regulator, receiver
C3L23_RS06685	COG3850	Histidine kinase
C3L23_RS06685	COG4999	Histidine kinase
C3L23_RS06685	COG2205	protein histidine kinase activity
C3L23_RS06695	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C3L23_RS06700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C3L23_RS06705	COG3706	GGDEF domain
C3L23_RS06730	COG0785	Cytochrome C biogenesis protein
C3L23_RS06740	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C3L23_RS06745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C3L23_RS06750	COG0247	lactate metabolic process
C3L23_RS06775	COG1305	Transglutaminase-like
C3L23_RS06785	COG0425	Belongs to the sulfur carrier protein TusA family
C3L23_RS06790	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C3L23_RS06810	COG2199	diguanylate cyclase activity
C3L23_RS06810	COG2203	Gaf domain
C3L23_RS06815	COG4565	transcriptional regulatory protein
C3L23_RS06820	COG0642	Histidine kinase
C3L23_RS06845	COG3383	formate dehydrogenase (NAD+) activity
C3L23_RS06855	COG0437	4 iron, 4 sulfur cluster binding
C3L23_RS06865	COG0725	ABC transporter, periplasmic molybdate-binding protein
C3L23_RS06870	COG3842	ATPase activity
C3L23_RS06875	COG4149	molybdate abc transporter
C3L23_RS06880	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C3L23_RS06885	COG3383	formate dehydrogenase (NAD+) activity
C3L23_RS06900	COG3706	GGDEF domain
C3L23_RS06900	COG4251	negative regulation of phosphorylation
C3L23_RS06900	COG5001	Diguanylate cyclase
C3L23_RS06900	COG2203	Gaf domain
C3L23_RS06920	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C3L23_RS06935	COG1921	L-seryl-tRNASec selenium transferase activity
C3L23_RS06945	COG0254	rRNA binding
C3L23_RS06950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C3L23_RS06955	COG0133	tryptophan synthase activity
C3L23_RS06965	COG0481	GTPase activity
C3L23_RS06980	COG0587	DNA-directed DNA polymerase activity
C3L23_RS06995	COG3287	FIST C domain
C3L23_RS06995	COG2199	diguanylate cyclase activity
C3L23_RS06995	COG2200	EAL domain
C3L23_RS07005	COG0724	RNA recognition motif
C3L23_RS07025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C3L23_RS07030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C3L23_RS07035	COG3706	GGDEF domain
C3L23_RS07040	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3L23_RS07040	COG1776	CheC inhibitor of MCP methylation
C3L23_RS07045	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3L23_RS07060	COG0455	bacterial-type flagellum organization
C3L23_RS07065	COG1419	protein localization to endoplasmic reticulum
C3L23_RS07070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C3L23_RS07075	COG0006	proline dipeptidase activity
C3L23_RS07080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C3L23_RS07085	COG0402	S-adenosylhomocysteine deaminase activity
C3L23_RS07095	COG1674	ftsk spoiiie
C3L23_RS07095	COG1196	nuclear chromosome segregation
C3L23_RS07100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3L23_RS07105	COG1570	exodeoxyribonuclease VII activity
C3L23_RS07110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C3L23_RS07115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C3L23_RS07120	COG0629	single-stranded DNA binding
C3L23_RS07125	COG0360	Binds together with S18 to 16S ribosomal RNA
C3L23_RS07135	COG0318	PFAM AMP-dependent synthetase and ligase
C3L23_RS07140	COG0642	Histidine kinase
C3L23_RS07155	COG1459	type II secretion system
C3L23_RS07220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C3L23_RS07225	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C3L23_RS07240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C3L23_RS07245	COG0037	tRNA processing
C3L23_RS07255	COG0823	Involved in the tonB-independent uptake of proteins
C3L23_RS07275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C3L23_RS07280	COG0268	Binds directly to 16S ribosomal RNA
C3L23_RS07285	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C3L23_RS07315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C3L23_RS07320	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C3L23_RS07325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C3L23_RS07330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C3L23_RS07335	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C3L23_RS07340	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C3L23_RS07345	COG0251	oxidation-reduction process
C3L23_RS07355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C3L23_RS07360	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C3L23_RS07380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C3L23_RS07385	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C3L23_RS07395	COG1007	ATP synthesis coupled electron transport
C3L23_RS07400	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3L23_RS07405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3L23_RS07410	COG0713	ATP synthesis coupled electron transport
C3L23_RS07430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3L23_RS07430	COG0649	NAD binding
C3L23_RS07435	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3L23_RS07440	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3L23_RS07450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C3L23_RS07455	COG0745	RESPONSE REGULATOR receiver
C3L23_RS07460	COG2205	protein histidine kinase activity
C3L23_RS07460	COG0784	Response regulator, receiver
C3L23_RS07495	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C3L23_RS07510	COG5001	Diguanylate cyclase
C3L23_RS07510	COG3300	MHYT domain
C3L23_RS07530	COG1217	gtp-binding protein TYPA
C3L23_RS07535	COG3290	protein histidine kinase activity
C3L23_RS07535	COG0840	transmembrane signaling receptor activity
C3L23_RS07555	COG1749	Flagellar hook protein flgE
C3L23_RS07570	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C3L23_RS07570	COG1796	DNA polymerase
C3L23_RS07590	COG1519	Transferase
C3L23_RS07590	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C3L23_RS07600	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C3L23_RS07605	COG0752	glycyl-tRNA synthetase alpha subunit
C3L23_RS07625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C3L23_RS07630	COG0826	peptidase U32
C3L23_RS07640	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C3L23_RS07645	COG2814	Major facilitator Superfamily
C3L23_RS07650	COG1706	bacterial-type flagellum-dependent cell motility
C3L23_RS07655	COG3951	Flagellar rod assembly protein muramidase FlgJ
C3L23_RS07670	COG1256	bacterial-type flagellum assembly
C3L23_RS07685	COG0356	it plays a direct role in the translocation of protons across the membrane
C3L23_RS07700	COG0287	Prephenate dehydrogenase
C3L23_RS07705	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C3L23_RS07710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C3L23_RS07715	COG1862	Preprotein translocase
C3L23_RS07720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3L23_RS07725	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3L23_RS07735	COG0495	leucyl-tRNA aminoacylation
C3L23_RS07750	COG0285	dihydrofolate synthase activity
C3L23_RS07755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C3L23_RS07765	COG0514	ATP-dependent DNA helicase (RecQ)
C3L23_RS07775	COG2095	MarC family integral membrane protein
C3L23_RS07780	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C3L23_RS07810	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C3L23_RS07815	COG0459	protein refolding
C3L23_RS07820	COG0335	large ribosomal subunit rRNA binding
C3L23_RS07825	COG0840	transmembrane signaling receptor activity
C3L23_RS07830	COG0336	Belongs to the RNA methyltransferase TrmD family
C3L23_RS07835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C3L23_RS07845	COG0228	four-way junction DNA binding
C3L23_RS07850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C3L23_RS07855	COG0564	pseudouridine synthase activity
C3L23_RS07870	COG0243	molybdopterin cofactor binding
C3L23_RS07875	COG0437	4 iron, 4 sulfur cluster binding
C3L23_RS07885	COG0446	pyridine nucleotide-disulphide oxidoreductase
C3L23_RS07895	COG3118	belongs to the thioredoxin family
C3L23_RS07905	COG0492	ferredoxin-NADP+ reductase activity
C3L23_RS07910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C3L23_RS07915	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C3L23_RS07920	COG1242	4 iron, 4 sulfur cluster binding
C3L23_RS07925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C3L23_RS07930	COG2203	Gaf domain
C3L23_RS07930	COG2199	diguanylate cyclase activity
C3L23_RS07935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3L23_RS07940	COG1418	mRNA catabolic process
C3L23_RS07955	COG0552	protein localization to endoplasmic reticulum
C3L23_RS07965	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C3L23_RS07970	COG0484	heat shock protein binding
C3L23_RS07975	COG2226	methyltransferase
C3L23_RS07980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3L23_RS07980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3L23_RS07985	COG0779	Required for maturation of 30S ribosomal subunits
C3L23_RS07990	COG0561	phosphatase activity
C3L23_RS07995	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C3L23_RS08000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C3L23_RS08010	COG0083	homoserine kinase activity
C3L23_RS08020	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C3L23_RS08025	COG0850	regulation of cytokinetic process
C3L23_RS08035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C3L23_RS08040	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C3L23_RS08045	COG0531	amino acid
C3L23_RS08050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C3L23_RS08060	COG0513	Belongs to the DEAD box helicase family
C3L23_RS08070	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C3L23_RS08070	COG0140	phosphoribosyl-ATP diphosphatase activity
C3L23_RS08085	COG1012	belongs to the aldehyde dehydrogenase family
C3L23_RS08100	COG0579	oxidoreductase
C3L23_RS08135	COG0069	glutamate synthase activity
C3L23_RS08135	COG0067	glutamate synthase
C3L23_RS08135	COG0070	glutamate synthase
C3L23_RS08140	COG0247	lactate metabolic process
C3L23_RS08145	COG1139	Iron-sulfur cluster binding protein
C3L23_RS08155	COG2199	diguanylate cyclase activity
C3L23_RS08155	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C3L23_RS08170	COG0644	oxidoreductase
C3L23_RS08190	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C3L23_RS08195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3L23_RS08200	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C3L23_RS08205	COG2171	N-acyltransferase activity
C3L23_RS08215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C3L23_RS08230	COG0432	Pfam Uncharacterised protein family UPF0047
C3L23_RS08235	COG1187	pseudouridine synthase activity
C3L23_RS08240	COG0517	IMP dehydrogenase activity
C3L23_RS08240	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C3L23_RS08245	COG1049	propionate catabolic process, 2-methylcitrate cycle
C3L23_RS08255	COG4399	Belongs to the UPF0754 family
C3L23_RS08270	COG2089	acid synthase
C3L23_RS08285	COG1083	cytidylyl-transferase
C3L23_RS08290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C3L23_RS08295	COG1086	Polysaccharide biosynthesis protein
C3L23_RS08305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3L23_RS08310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3L23_RS08340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C3L23_RS08345	COG0024	Methionine aminopeptidase
C3L23_RS08350	COG0201	protein transport
C3L23_RS08355	COG0200	Binds to the 23S rRNA
C3L23_RS08360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C3L23_RS08365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C3L23_RS08370	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C3L23_RS08375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C3L23_RS08380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C3L23_RS08385	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C3L23_RS08390	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C3L23_RS08395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C3L23_RS08400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C3L23_RS08405	COG0255	Belongs to the universal ribosomal protein uL29 family
C3L23_RS08410	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C3L23_RS08415	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C3L23_RS08420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C3L23_RS08425	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C3L23_RS08430	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C3L23_RS08435	COG0089	rRNA binding
C3L23_RS08440	COG0088	Forms part of the polypeptide exit tunnel
C3L23_RS08445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C3L23_RS08450	COG0051	transcription antitermination factor activity, RNA binding
C3L23_RS08455	COG1611	Belongs to the LOG family
C3L23_RS08470	COG0842	Transport permease protein
C3L23_RS08475	COG1129	ABC transporter
C3L23_RS08475	COG0842	Transport permease protein
C3L23_RS08480	COG1129	ABC transporter
C3L23_RS08480	COG0842	Transport permease protein
C3L23_RS08495	COG2814	Major facilitator Superfamily
C3L23_RS08515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C3L23_RS08520	COG1215	transferase activity, transferring glycosyl groups
C3L23_RS08525	COG0859	PFAM glycosyl transferase family 9
C3L23_RS08535	COG0438	transferase activity, transferring glycosyl groups
C3L23_RS08545	COG1215	transferase activity, transferring glycosyl groups
C3L23_RS08550	COG2244	polysaccharide biosynthetic process
C3L23_RS08555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C3L23_RS08570	COG1181	Belongs to the D-alanine--D-alanine ligase family
C3L23_RS08590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C3L23_RS08620	COG1596	polysaccharide export
C3L23_RS08620	COG1555	photosystem II stabilization
C3L23_RS08630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3L23_RS08635	COG2895	sulfate adenylyltransferase (ATP) activity
C3L23_RS08640	COG0175	sulfate reduction
C3L23_RS08645	COG0529	Catalyzes the synthesis of activated sulfate
C3L23_RS08670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C3L23_RS08675	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C3L23_RS08680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C3L23_RS08685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C3L23_RS08690	COG0142	geranyltranstransferase activity
C3L23_RS08700	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C3L23_RS08705	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C3L23_RS08710	COG3411	Ferredoxin
C3L23_RS08715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C3L23_RS08730	COG0203	ribosomal protein L17
C3L23_RS08735	COG0202	RNA polymerase activity
C3L23_RS08740	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C3L23_RS08745	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C3L23_RS08750	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C3L23_RS08755	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C3L23_RS08760	COG2252	PERMEase
C3L23_RS08765	COG0071	Belongs to the small heat shock protein (HSP20) family
C3L23_RS08775	COG0668	transmembrane transport
C3L23_RS08780	COG0768	penicillin binding
C3L23_RS08795	COG1815	bacterial-type flagellum-dependent cell motility
C3L23_RS08800	COG0772	Belongs to the SEDS family
C3L23_RS08810	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C3L23_RS08815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C3L23_RS08815	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C3L23_RS08835	COG0859	PFAM glycosyl transferase family 9
C3L23_RS08850	COG0859	PFAM glycosyl transferase family 9
C3L23_RS08860	COG0859	PFAM glycosyl transferase family 9
C3L23_RS08870	COG0859	PFAM glycosyl transferase family 9
C3L23_RS08890	COG1132	(ABC) transporter
C3L23_RS08895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C3L23_RS08895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C3L23_RS08910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C3L23_RS08915	COG0606	chelatase, subunit chli
C3L23_RS08920	COG0242	peptide deformylase activity
C3L23_RS08930	COG0740	serine-type endopeptidase activity
C3L23_RS08935	COG0544	peptidyl-prolyl cis-trans isomerase activity
C3L23_RS08940	COG0302	gtp cyclohydrolase
C3L23_RS08945	COG1157	protein secretion by the type III secretion system
C3L23_RS08950	COG3300	MHYT domain
C3L23_RS08950	COG5001	Diguanylate cyclase
C3L23_RS09000	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C3L23_RS09085	COG0582	viral genome integration into host DNA
C3L23_RS09090	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C3L23_RS09095	COG1132	(ABC) transporter
C3L23_RS09105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C3L23_RS09110	COG0129	dihydroxy-acid dehydratase activity
C3L23_RS09130	COG2078	PFAM AMMECR1 domain protein
C3L23_RS09150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C3L23_RS09160	COG1215	transferase activity, transferring glycosyl groups
C3L23_RS09165	COG0726	polysaccharide deacetylase
C3L23_RS09165	COG1649	PFAM Uncharacterised BCR, COG1649
C3L23_RS09220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C3L23_RS09230	COG0564	pseudouridine synthase activity
C3L23_RS09265	COG1121	(ABC) transporter
C3L23_RS09270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3L23_RS09285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3L23_RS09335	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C3L23_RS09335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3L23_RS09340	COG0418	dihydroorotase activity
C3L23_RS09355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C3L23_RS09360	COG0107	imidazoleglycerol-phosphate synthase activity
C3L23_RS09375	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C3L23_RS09385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3L23_RS09395	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C3L23_RS09400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C3L23_RS09410	COG2877	3-deoxy-8-phosphooctulonate synthase activity
C3L23_RS09415	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C3L23_RS09425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C3L23_RS09430	COG2200	EAL domain
C3L23_RS09430	COG2199	diguanylate cyclase activity
C3L23_RS09430	COG3287	FIST C domain
C3L23_RS09440	COG2860	membrane
C3L23_RS09445	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group