locus-tag	class	description
H3L91_RS00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
H3L91_RS00015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
H3L91_RS00020	ENOG41086UY	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H3L91_RS00070	ENOG4105D1F	ATP-binding protein
H3L91_RS00095	ENOG4105DJ4	phosphatidylserine decarboxylase
H3L91_RS00115	ENOG4105NIV	Esterase
H3L91_RS00120	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
H3L91_RS00160	ENOG4105DR5	peptidase
H3L91_RS00170	ENOG4108ZAI	phosphatidylglycerophosphatase a
H3L91_RS00175	ENOG4105EZR	dyp-type peroxidase family protein
H3L91_RS00190	ENOG4105DB7	PHP domain protein
H3L91_RS00195	ENOG4105EXG	Transcriptional regulator
H3L91_RS00200	ENOG4105MGM	doxx family
H3L91_RS00235	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
H3L91_RS00250	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
H3L91_RS00255	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
H3L91_RS00260	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
H3L91_RS00270	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
H3L91_RS00280	ENOG4107QHF	type ii secretion system protein e
H3L91_RS00295	ENOG4105WD1	Membrane
H3L91_RS00300	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
H3L91_RS00320	ENOG4105T95	Thiol disulfide interChange protein
H3L91_RS00330	ENOG4105CT1	(ABC) transporter
H3L91_RS00335	ENOG4105CDA	abc transporter atp-binding protein
H3L91_RS00345	ENOG4105E5Q	amino acid AbC transporter
H3L91_RS00350	ENOG4105CJR	Integral membrane protein (MviN
H3L91_RS00385	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
H3L91_RS00395	ENOG4105CW7	secretion protein, HlyD family
H3L91_RS00445	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H3L91_RS00475	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
H3L91_RS00480	ENOG4105CAK	Cell division ATP-binding protein ftsE
H3L91_RS00485	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
H3L91_RS00490	ENOG4107QMS	site-determining protein
H3L91_RS00495	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
H3L91_RS00500	ENOG4105C5Q	Transcriptional regulator
H3L91_RS00505	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
H3L91_RS00510	ENOG4108Z0R	Transferase
H3L91_RS00515	ENOG4105CJW	magnesium transporter
H3L91_RS00535	ENOG4108WQI	RNA Polymerase
H3L91_RS00555	ENOG4109045	doxx family
H3L91_RS00580	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
H3L91_RS00585	ENOG4105ECY	inositol monophosphatase
H3L91_RS00595	ENOG4108S0S	Nucleotidyl transferase
H3L91_RS00620	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
H3L91_RS00640	ENOG4107QPK	)-transporter
H3L91_RS00645	ENOG4105FE9	pseudouridine synthase
H3L91_RS00650	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
H3L91_RS00665	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
H3L91_RS00685	ENOG4105CEN	a g-specific adenine glycosylase
H3L91_RS00695	ENOG4105CSM	endonuclease III
H3L91_RS00700	ENOG4105EM2	membrane
H3L91_RS00710	ENOG4108XC3	NADH ubiquinone oxidoreductase
H3L91_RS00715	ENOG4105C5H	ABC transporter
H3L91_RS00730	ENOG4105E7U	AraC family transcriptional regulator
H3L91_RS00765	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H3L91_RS00790	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
H3L91_RS00810	ENOG4108YYH	Nadph-dependent fmn reductase
H3L91_RS00820	ENOG4105DFP	Integrase
H3L91_RS00875	ENOG4105CA3	membrane-bound lytic murein transglycosylase
H3L91_RS00900	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
H3L91_RS00905	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
H3L91_RS00910	ENOG4105C10	Electron transfer flavoprotein
H3L91_RS00915	ENOG4105BZJ	Electron transfer flavoprotein
H3L91_RS00920	ENOG4105D16	lipopolysaccharide heptosyltransferase i
H3L91_RS00925	ENOG4108RWI	nicotinamidase
H3L91_RS00930	ENOG4108R96	Methyltransferase, YaeB family
H3L91_RS00945	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
H3L91_RS01000	ENOG4107TCE	N-acetyltransferase
H3L91_RS01030	ENOG4105F2I	Transposase
H3L91_RS01035	ENOG4105CQ0	ABC transporter
H3L91_RS01055	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
H3L91_RS01065	ENOG4107QN1	sodium solute
H3L91_RS01125	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
H3L91_RS01130	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
H3L91_RS01135	ENOG41072GX	Peptidase M22 Glycoprotease
H3L91_RS01140	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
H3L91_RS01150	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
H3L91_RS01155	ENOG4108IJ0	Aspartate ammonia-lyase
H3L91_RS01190	ENOG4105C2D	reductase
H3L91_RS01195	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H3L91_RS01220	ENOG4108SHN	Glycosyl transferase, family 2
H3L91_RS01240	ENOG4105DTN	riboflavin biosynthesis protein ribF
H3L91_RS01270	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H3L91_RS01330	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
H3L91_RS01345	ENOG4105CNM	Receptor
H3L91_RS01375	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H3L91_RS01385	ENOG4105E9S	glutaredoxin 2
H3L91_RS01400	ENOG4105II7	pyrroline-5-carboxylate reductase
H3L91_RS01410	ENOG4105DFA	alanine racemase domain protein
H3L91_RS01415	ENOG4105CZX	twitching motility protein
H3L91_RS01420	ENOG4105CZX	twitching motility protein
H3L91_RS01440	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H3L91_RS01445	ENOG4108V2W	Carbonate dehydratase
H3L91_RS01450	ENOG4107UWN	reductase
H3L91_RS01460	ENOG4105CVJ	phosphoglycerate mutase
H3L91_RS01470	ENOG4105BZG	amino acid carrier protein
H3L91_RS01475	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
H3L91_RS01485	ENOG4107RNH	Outer membrane receptor FepA
H3L91_RS01500	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
H3L91_RS01540	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3L91_RS01545	ENOG4105DU1	integral membrane protein, terc
H3L91_RS01550	ENOG4105KB2	stringent starvation protein b
H3L91_RS01555	ENOG4107MKT	Stringent starvation protein a
H3L91_RS01560	ENOG4105EIX	cytochrome c1
H3L91_RS01565	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H3L91_RS01570	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H3L91_RS01575	ENOG4107QNR	UPF0135 protein
H3L91_RS01580	ENOG4105DGW	oligopeptidase A
H3L91_RS01585	ENOG4105CGY	Dna recombination protein
H3L91_RS01590	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
H3L91_RS01595	ENOG4105DVT	helicase
H3L91_RS01600	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
H3L91_RS01605	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
H3L91_RS01640	ENOG4105EAH	synthase
H3L91_RS01655	ENOG4105DZ2	Transcriptional regulator
H3L91_RS01660	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H3L91_RS01670	ENOG4107QJE	Chromosome Partitioning Protein
H3L91_RS01675	ENOG4105KVH	Transcriptional regulator
H3L91_RS01680	ENOG4107FW0	short-chain dehydrogenase reductase
H3L91_RS01735	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
H3L91_RS01755	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
H3L91_RS01760	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H3L91_RS01770	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H3L91_RS01790	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
H3L91_RS01825	ENOG4107QTF	adenylosuccinate lyase
H3L91_RS01840	ENOG4105D2N	Aldolase
H3L91_RS01920	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
H3L91_RS01940	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
H3L91_RS01945	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
H3L91_RS02005	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
H3L91_RS02010	ENOG4105C0H	protease
H3L91_RS02025	ENOG4105CHR	reductase
H3L91_RS02035	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
H3L91_RS02040	ENOG4107YB6	acetyltransferase, (GNAT) family
H3L91_RS02060	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3L91_RS02070	ENOG4105BZM	domain protein
H3L91_RS02085	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
H3L91_RS02100	ENOG4105C4R	Atp-dependent dna helicase
H3L91_RS02105	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
H3L91_RS02110	ENOG4105DUX	Transporter
H3L91_RS02130	ENOG4105NAU	thioesterase Superfamily protein
H3L91_RS02160	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
H3L91_RS02170	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
H3L91_RS02185	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
H3L91_RS02190	ENOG4105C5I	Dehydrogenase
H3L91_RS02210	ENOG4105JKW	Valine--pyruvate aminotransferase
H3L91_RS02240	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
H3L91_RS02255	ENOG4105BZ1	(ABC) transporter
H3L91_RS02280	ENOG4106H78	methyltransferase
H3L91_RS02285	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
H3L91_RS02350	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H3L91_RS02355	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
H3L91_RS02370	ENOG4108Z20	Acyl-transferase
H3L91_RS02375	ENOG4105EHV	domain protein
H3L91_RS02380	ENOG4107QN2	dihydrolipoyl dehydrogenase
H3L91_RS02400	ENOG41081UC	Inherit from COG: Competence protein
H3L91_RS02405	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
H3L91_RS02420	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
H3L91_RS02440	ENOG4105EQ2	LysR family Transcriptional regulator
H3L91_RS02475	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
H3L91_RS02480	ENOG4105KVH	Transcriptional regulator
H3L91_RS02485	ENOG4105F2I	Transposase
H3L91_RS02540	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
H3L91_RS02555	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
H3L91_RS02575	ENOG4105MZU	cell filamentation protein
H3L91_RS02605	ENOG4105CPF	Cell wall formation (By similarity)
H3L91_RS02615	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
H3L91_RS02630	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
H3L91_RS02655	ENOG4105C2X	Arabinose 5-phosphate isomerase
H3L91_RS02675	ENOG4105D82	Glutamate dehydrogenase
H3L91_RS02685	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
H3L91_RS02690	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
H3L91_RS02695	ENOG4105VUF	Transcriptional regulator
H3L91_RS02705	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H3L91_RS02725	ENOG4105VCQ	rubredoxin
H3L91_RS02730	ENOG4105CDU	Replicative dna helicase
H3L91_RS02755	ENOG4108ZUW	Major pilin subunit
H3L91_RS02760	ENOG4105FE1	phytoene synthase
H3L91_RS02775	ENOG4108K5P	(LipO)protein
H3L91_RS02805	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
H3L91_RS02835	ENOG4108NKP	c4-dicarboxylate transporter malic acid transport protein
H3L91_RS02840	ENOG4105DHQ	Histidine kinase
H3L91_RS02845	ENOG4105DIK	(ABC) transporter
H3L91_RS02855	ENOG4105CC5	ABC transporter
H3L91_RS02860	ENOG4105DSE	periplasmic solute binding protein
H3L91_RS02865	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
H3L91_RS02870	ENOG4108UMI	ABC transporter, permease
H3L91_RS02895	ENOG4105KVH	Transcriptional regulator
H3L91_RS02900	ENOG4105CIS	alcohol dehydrogenase
H3L91_RS02905	ENOG4105CSC	Glucose uptake protein
H3L91_RS02910	ENOG4105CV8	reductase
H3L91_RS02925	ENOG4105EMU	Dehydrogenase
H3L91_RS02930	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
H3L91_RS02940	ENOG4107RP9	extracellular solute-binding protein, family 3
H3L91_RS02950	ENOG4107YTP	response regulator receiver protein
H3L91_RS02955	ENOG4105CBS	Chea signal transduction histidine kinase
H3L91_RS02965	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
H3L91_RS02990	ENOG4105DZR	Type I site-specific deoxyribonuclease
H3L91_RS02995	ENOG4105EKX	Restriction modification system DNA (Specificity
H3L91_RS03000	ENOG4105CVR	type I restriction-modification system
H3L91_RS03035	ENOG4105CNU	cell division protein FtsK
H3L91_RS03045	ENOG4105MPD	Cytochrome
H3L91_RS03055	ENOG4105C7K	acetolactate synthase
H3L91_RS03060	ENOG4108ZP8	Acetolactate synthase small subunit
H3L91_RS03075	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H3L91_RS03080	ENOG4105ES5	Histidine kinase
H3L91_RS03115	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H3L91_RS03125	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H3L91_RS03135	ENOG4105GKE	subunit e
H3L91_RS03150	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
H3L91_RS03170	ENOG4105DF2	NADH dehydrogenase subunit j
H3L91_RS03190	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
H3L91_RS03200	ENOG4105C8S	subunit m
H3L91_RS03220	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
H3L91_RS03230	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
H3L91_RS03255	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
H3L91_RS03260	ENOG4105EHG	Permease protein
H3L91_RS03285	ENOG4105C3G	gtp-binding protein
H3L91_RS03305	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
H3L91_RS03310	ENOG4105C4R	Atp-dependent dna helicase
H3L91_RS03315	ENOG4105CJ1	ABC, transporter
H3L91_RS03325	ENOG4105D22	carbon starvation protein
H3L91_RS03335	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
H3L91_RS03350	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H3L91_RS03380	ENOG4105DFP	Integrase
H3L91_RS03530	ENOG4105RWQ	Protein of unknown function (DUF1364)
H3L91_RS03555	ENOG4108N0N	Phage Terminase Large Subunit
H3L91_RS03565	ENOG4108C66	Inherit from COG: DNA primase
H3L91_RS03670	ENOG4105VXN	addiction module toxin, RelE StbE family
H3L91_RS03745	ENOG4106050	phage regulatory protein, rha family
H3L91_RS03780	ENOG4107UQD	Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity)
H3L91_RS03810	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H3L91_RS03830	ENOG4105KNE	Phosphatidate cytidylyltransferase
H3L91_RS03835	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
H3L91_RS03850	ENOG41080IJ	Diacylglycerol kinase
H3L91_RS03855	ENOG4105D7Z	glutathione synthase
H3L91_RS03860	ENOG4105K5B	UPF0225 protein
H3L91_RS03885	ENOG4105DHS	permease protein
H3L91_RS03890	ENOG4105CM4	permease protein
H3L91_RS03895	ENOG4108IPW	abc transporter atp-binding protein
H3L91_RS03905	ENOG4107RDB	Major Facilitator
H3L91_RS03915	ENOG4105EVN	Prephenate dehydrogenase
H3L91_RS03940	ENOG4105F2I	Transposase
H3L91_RS03950	ENOG4105EUJ	GTP cyclohydrolase i
H3L91_RS04005	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
H3L91_RS04020	ENOG4105KTH	gatB Yqey
H3L91_RS04045	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
H3L91_RS04055	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H3L91_RS04065	ENOG4105C9X	ppx gppa phosphatase
H3L91_RS04080	ENOG4105C5X	domain protein
H3L91_RS04095	ENOG4105FR1	rard protein
H3L91_RS04100	ENOG4105C6K	Malic enzyme
H3L91_RS04135	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
H3L91_RS04200	ENOG4108F3G	Type I restriction-modification system, R subunit
H3L91_RS04240	ENOG4105EQ2	LysR family Transcriptional regulator
H3L91_RS04250	ENOG4108ZT1	Transcriptional regulator
H3L91_RS04260	ENOG4108KTG	Membrane protein, drug metabolite transporter
H3L91_RS04270	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
H3L91_RS04280	ENOG4108W6C	Dehydrogenase
H3L91_RS04290	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
H3L91_RS04295	ENOG4107SC1	transglycosylase
H3L91_RS04305	ENOG4105CUV	Homoserine Kinase
H3L91_RS04345	ENOG4105CI3	gtp-binding protein typa
H3L91_RS04350	ENOG4108YRX	Iron-storage protein
H3L91_RS04360	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
H3L91_RS04380	ENOG4105F2I	Transposase
H3L91_RS04385	ENOG4105CSR	polyphosphate kinase 2
H3L91_RS04395	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
H3L91_RS04440	ENOG4105D6E	homoserine dehydrogenase
H3L91_RS04450	ENOG4105ECY	inositol monophosphatase
H3L91_RS04485	ENOG4106IKR	
H3L91_RS04530	ENOG4105DFP	Integrase
H3L91_RS04570	ENOG4105CHC	glucokinase (EC 2.7.1.2)
H3L91_RS04600	ENOG4105DFD	Na H antiporter
H3L91_RS04610	ENOG4105D3Q	Sugar transferase
H3L91_RS04620	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
H3L91_RS04625	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
H3L91_RS04630	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
H3L91_RS04640	ENOG4105EHM	Aminoglycoside phosphotransferase
H3L91_RS04650	ENOG4105XA0	heptosyltransferase ii
H3L91_RS04690	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
H3L91_RS04700	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
H3L91_RS04705	ENOG4105DKP	glycosyl transferase, family 9
H3L91_RS04720	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
H3L91_RS04780	ENOG4105C3M	thioredoxin reductase
H3L91_RS04785	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
H3L91_RS04790	ENOG4105DQR	SNARE associated Golgi
H3L91_RS04795	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
H3L91_RS04805	ENOG4105VF7	tolerance protein
H3L91_RS04860	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
H3L91_RS04895	ENOG4105C3F	Signal peptidase i
H3L91_RS04900	ENOG4105D52	delta-aminolevulinic acid dehydratase
H3L91_RS04940	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
H3L91_RS04945	ENOG41061WM	D-Alanyl-D-Alanine
H3L91_RS04950	ENOG4105K3M	)-transporter
H3L91_RS04960	ENOG4105CFU	surface antigen
H3L91_RS04970	ENOG4108NEV	two component transcriptional regulator, LytTR family
H3L91_RS04975	ENOG4105C28	cystathionine
H3L91_RS04980	ENOG4105C03	ribonuclease
H3L91_RS04990	ENOG4108ZPB	UPF0306 protein
H3L91_RS05005	ENOG4105C5H	ABC transporter
H3L91_RS05030	ENOG4105HF0	Membrane
H3L91_RS05035	ENOG4105F1S	paraquat-inducible protein a
H3L91_RS05045	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
H3L91_RS05050	ENOG4105C11	sulfate adenylyltransferase), subunit 2
H3L91_RS05055	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
H3L91_RS05085	ENOG4105XPH	Ferredoxin
H3L91_RS05090	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
H3L91_RS05105	ENOG4108HRK	Histidine kinase
H3L91_RS05115	ENOG4108TIT	dATP pyrophosphohydrolase
H3L91_RS05120	ENOG4105EGS	Mechanosensitive ion channel
H3L91_RS05125	ENOG4108ZUW	Major pilin subunit
H3L91_RS05135	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
H3L91_RS05145	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
H3L91_RS05150	ENOG4105EA8	2-Nitropropane dioxygenase
H3L91_RS05155	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
H3L91_RS05180	ENOG4108UJV	acyl-CoA thioesterase i
H3L91_RS05190	ENOG4108R6K	riboflavin synthase, subunit alpha
H3L91_RS05195	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
H3L91_RS05200	ENOG4108YZA	Nitrogen regulatory protein pii
H3L91_RS05205	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
H3L91_RS05220	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
H3L91_RS05245	ENOG41084A1	Protein CrcB homolog
H3L91_RS05255	ENOG4107QRG	dna polymerase iii
H3L91_RS05265	ENOG4105F8V	Hydrolase, tatD family
H3L91_RS05270	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
H3L91_RS05290	ENOG4108RH0	Crea protein
H3L91_RS05300	ENOG4105EE5	Membrane protein terC
H3L91_RS05305	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
H3L91_RS05325	ENOG4105WVQ	Fe-S assembly protein IscX
H3L91_RS05330	ENOG4108ZIT	Ferredoxin, 2FE-2S
H3L91_RS05340	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
H3L91_RS05355	ENOG4108Z4V	iron-sulfur cluster assembly
H3L91_RS05365	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
H3L91_RS05385	ENOG4105DMF	Dehydrogenase
H3L91_RS05405	ENOG4105F27	Major Facilitator
H3L91_RS05410	ENOG410827H	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
H3L91_RS05420	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
H3L91_RS05435	ENOG4107QIJ	Aconitate hydratase 2
H3L91_RS05485	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H3L91_RS05495	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
H3L91_RS05500	ENOG4105KA3	membrAne
H3L91_RS05505	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
H3L91_RS05515	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H3L91_RS05520	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H3L91_RS05565	ENOG4105CM2	brancheD-chain amino acid aminotransferase
H3L91_RS05605	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
H3L91_RS05620	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
H3L91_RS05625	ENOG4105KPV	Transcriptional regulator
H3L91_RS05640	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H3L91_RS05665	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
H3L91_RS05675	ENOG4105C28	cystathionine
H3L91_RS05680	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H3L91_RS05705	ENOG4105CNM	Receptor
H3L91_RS05710	ENOG4105C8P	)-transporter
H3L91_RS05715	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H3L91_RS05720	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
H3L91_RS05795	ENOG4105DP0	ferredoxin-NADP reductase
H3L91_RS05800	ENOG4105DJ0	Poly(A) Polymerase
H3L91_RS05815	ENOG4105CFH	Aspartokinase
H3L91_RS05825	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
H3L91_RS05835	ENOG4108Z4T	Peptidase M50
H3L91_RS05845	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
H3L91_RS05870	ENOG4107QMH	DNA methylase
H3L91_RS05875	ENOG4105UGU	tonB-dependent Receptor
H3L91_RS05890	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H3L91_RS05910	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H3L91_RS05915	ENOG41076E6	Uroporphyrinogen-III Synthase
H3L91_RS05935	ENOG4105D6U	Sodium Glutamate Symporter
H3L91_RS06000	ENOG4105DFP	Integrase
H3L91_RS06015	ENOG4108R99	pseudouridine synthase
H3L91_RS06030	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
H3L91_RS06040	ENOG41077RS	Phosphatase
H3L91_RS06045	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
H3L91_RS06050	ENOG4105CGK	Exodeoxyribonuclease III
H3L91_RS06060	ENOG4105C26	Dehydrogenase
H3L91_RS06065	ENOG4108EC8	DNA internalization-related competence protein ComEC
H3L91_RS06145	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
H3L91_RS06155	ENOG4107QN2	dihydrolipoyl dehydrogenase
H3L91_RS06165	ENOG4107QSN	dihydrolipoamide acetyltransferase
H3L91_RS06170	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
H3L91_RS06195	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
H3L91_RS06200	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
H3L91_RS06210	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
H3L91_RS06245	ENOG4105DFU	Cell wall formation (By similarity)
H3L91_RS06265	ENOG4105CMI	transporter
H3L91_RS06270	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
H3L91_RS06275	ENOG4105C1A	potassium transporter peripheral membrane
H3L91_RS06280	ENOG4105DSJ	YicC domain protein
H3L91_RS06315	ENOG4105C0P	Mg chelatase subunit ChlI
H3L91_RS06320	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
H3L91_RS06355	ENOG4105C2M	dna polymerase I
H3L91_RS06375	ENOG41062JF	Transcriptional regulator
H3L91_RS06395	ENOG4105D1S	lipid A biosynthesis
H3L91_RS06415	ENOG4105DFP	Integrase
H3L91_RS06475	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3L91_RS06480	ENOG410904N	short-chain dehydrogenase reductase
H3L91_RS06485	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
H3L91_RS06490	ENOG4105C2W	permease
H3L91_RS06505	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
H3L91_RS06510	ENOG4105CEY	Amp-dependent synthetase and ligase
H3L91_RS06515	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
H3L91_RS06525	ENOG4108SNK	aliphatic sulfonates import ATP-binding protein SsuB
H3L91_RS06535	ENOG4105QEW	
H3L91_RS06550	ENOG41069NU	Nitroreductase
H3L91_RS06555	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H3L91_RS06560	ENOG4105UCG	Domain of unknown function (DUF333)
H3L91_RS06565	ENOG4108Z6B	deaminase
H3L91_RS06570	ENOG4105CNI	cell division protein FtsW
H3L91_RS06575	ENOG4105CJN	penicillin-binding protein
H3L91_RS06610	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H3L91_RS06620	ENOG4105DFE	Dna adenine methylase
H3L91_RS06635	ENOG4108MJ5	VirK protein
H3L91_RS06650	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
H3L91_RS06690	ENOG4108R3D	Electron transport complex
H3L91_RS06710	ENOG4105CHM	Aminotransferase
H3L91_RS06740	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
H3L91_RS06770	ENOG4105UGU	tonB-dependent Receptor
H3L91_RS06780	ENOG4108ZAF	Molybdopterin
H3L91_RS06790	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
H3L91_RS06795	ENOG4108RCM	Nitroreductase
H3L91_RS06810	ENOG4105DQQ	Major facilitator superfamily MFS_1
H3L91_RS06815	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
H3L91_RS06820	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
H3L91_RS06825	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
H3L91_RS06830	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
H3L91_RS06840	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3L91_RS06845	ENOG4105E0C	molybdate abc transporter
H3L91_RS06855	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
H3L91_RS06860	ENOG4105D0D	Nitrate reductase 2, gamma subunit
H3L91_RS06865	ENOG4105R3A	Nitrate reductase
H3L91_RS06870	ENOG4108IUE	nitrate reductase beta subunit
H3L91_RS06880	ENOG4105CRU	nitrate reductase, alpha subunit
H3L91_RS06890	ENOG4105EHG	Permease protein
H3L91_RS06895	ENOG4105E0A	ABC, transporter
H3L91_RS06900	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
H3L91_RS06910	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
H3L91_RS06965	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
H3L91_RS06970	ENOG4105CFP	Peptidase U32
H3L91_RS06985	ENOG4105CUZ	uba thif-type nad fad binding protein
H3L91_RS07010	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
H3L91_RS07030	ENOG4105C59	p-type ATPase
H3L91_RS07045	ENOG4108R5S	membrane
H3L91_RS07050	ENOG4105DR4	Methyltransferase
H3L91_RS07055	ENOG4105C1J	atp-dependent rna helicase
H3L91_RS07060	ENOG4108JQ5	ABC transporter
H3L91_RS07065	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H3L91_RS07070	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H3L91_RS07080	ENOG4107QSI	ABC, transporter
H3L91_RS07090	ENOG4105CK7	Sodium proline symporter
H3L91_RS07095	ENOG4105C26	Dehydrogenase
H3L91_RS07110	ENOG4108TZV	Membrane
H3L91_RS07125	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
H3L91_RS07135	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
H3L91_RS07145	ENOG4105DFI	Membrane
H3L91_RS07155	ENOG4108HPI	phosphatidate Cytidylyltransferase
H3L91_RS07180	ENOG4105K63	Thioredoxin
H3L91_RS07185	ENOG4107RET	Isocitrate lyase
H3L91_RS07195	ENOG4105EX9	Membrane
H3L91_RS07205	ENOG4108HGY	Proline imino-peptidase
H3L91_RS07225	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
H3L91_RS07240	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
H3L91_RS07250	ENOG4107QP3	malate synthase g
H3L91_RS07255	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H3L91_RS07265	ENOG4105C5H	ABC transporter
H3L91_RS07275	ENOG4105WPN	DNA integration recombination invertion protein
H3L91_RS07280	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
H3L91_RS07285	ENOG4105FE9	pseudouridine synthase
H3L91_RS07300	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
H3L91_RS07305	ENOG4105J5G	Transferase hexapeptide repeat containing protein
H3L91_RS07310	ENOG4105C9A	Phoh family
H3L91_RS07315	ENOG4108TEB	UPF0114 protein
H3L91_RS07320	ENOG4107QKA	exodeoxyribonuclease V beta
H3L91_RS07325	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
H3L91_RS07330	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
H3L91_RS07335	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
H3L91_RS07345	ENOG4107T7U	Sulfatase
H3L91_RS07390	ENOG4107RN3	metallophosphoesterase
H3L91_RS07400	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
H3L91_RS07415	ENOG4105VEJ	Heat shock protein
H3L91_RS07420	ENOG4105CGZ	zinc metallopeptidase
H3L91_RS07430	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
H3L91_RS07440	ENOG4105D7A	ATP-binding protein
H3L91_RS07445	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H3L91_RS07460	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H3L91_RS07465	ENOG4105D82	Glutamate dehydrogenase
H3L91_RS07475	ENOG4105VUC	UPF0237 protein
H3L91_RS07480	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H3L91_RS07485	ENOG4108JQ5	ABC transporter
H3L91_RS07510	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3L91_RS07515	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
H3L91_RS07520	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H3L91_RS07525	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3L91_RS07530	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H3L91_RS07535	ENOG4105KJF	protein tyrosine phosphatase
H3L91_RS07550	ENOG4108URH	decarboxylase
H3L91_RS07555	ENOG4107SRH	Nad-dependent epimerase dehydratase
H3L91_RS07565	ENOG4105C6K	Malic enzyme
H3L91_RS07575	ENOG4105C02	permease
H3L91_RS07580	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
H3L91_RS07585	ENOG4106WTF	Glycosyl transferase, family 2
H3L91_RS07590	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
H3L91_RS07595	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
H3L91_RS07625	ENOG4105C37	(CBS) domain
H3L91_RS07630	ENOG4105D0S	secretion protein (HlyD
H3L91_RS07640	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
H3L91_RS07650	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3L91_RS07655	ENOG4105F38	ABC transporter, permease
H3L91_RS07660	ENOG4105D38	putrescine abc transporter
H3L91_RS07680	ENOG4108IU3	tonb-dependent siderophore receptor
H3L91_RS07695	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
H3L91_RS07700	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
H3L91_RS07705	ENOG4107QR9	Iron-sulfur cluster binding protein
H3L91_RS07715	ENOG4108UK5	Transposase
H3L91_RS07745	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
H3L91_RS07760	ENOG4108PTX	LysR family Transcriptional regulator
H3L91_RS07765	ENOG4105KME	endoribonuclease L-psp
H3L91_RS07770	ENOG4105CI0	Citrate lyase
H3L91_RS07775	ENOG4105DP0	ferredoxin-NADP reductase
H3L91_RS07780	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
H3L91_RS07790	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
H3L91_RS07800	ENOG4105X23	Endonuclease Exonuclease phosphatase
H3L91_RS07820	ENOG4105DDQ	anthranilate synthase
H3L91_RS07860	ENOG4105BZU	Histidine kinase
H3L91_RS07865	ENOG4105WH1	Two component transcriptional regulator luxr family
H3L91_RS07885	ENOG4105E98	transcriptional regulator DeoR family
H3L91_RS07890	ENOG4105CN1	protease
H3L91_RS07905	ENOG4105D3G	Pseudouridine synthase
H3L91_RS07910	ENOG4105HDK	L-asparaginase
H3L91_RS07920	ENOG4105C5H	ABC transporter
H3L91_RS07950	ENOG4105EN6	Membrane
H3L91_RS07980	ENOG4107QMP	dna polymerase iii subunits gamma and tau
H3L91_RS08025	ENOG4105C2W	permease
H3L91_RS08030	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H3L91_RS08040	ENOG4105C2C	drug resistance transporter, Bcr CflA
H3L91_RS08045	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
H3L91_RS08055	ENOG4105CQ0	ABC transporter
H3L91_RS08085	ENOG4108JA2	transcriptioN-repair coupling factor
H3L91_RS08110	ENOG4107QYX	exodeoxyribonuclease v alpha
H3L91_RS08120	ENOG4108MVK	Receptor
H3L91_RS08135	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
H3L91_RS08140	ENOG4105BZ1	(ABC) transporter
H3L91_RS08280	ENOG4105K70	DNA-binding protein
H3L91_RS08335	ENOG4105M7P	phage repressor
H3L91_RS08395	ENOG4105CF2	Mu-like prophage FluMu protein GP28
H3L91_RS08400	ENOG4105QIB	mu-like prophage Flumu protein gp29
H3L91_RS08405	ENOG4108QUU	Morphogenesis Protein
H3L91_RS08410	ENOG4107XYH	virion morphogenesis protein
H3L91_RS08430	ENOG4105E7A	Glutamine amidotransferase
H3L91_RS08435	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
H3L91_RS08440	ENOG4105CGF	Aromatic amino acid aminotransferase
H3L91_RS08445	ENOG4105CV1	Transketolase (EC 2.2.1.1)
H3L91_RS08450	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
H3L91_RS08455	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
H3L91_RS08470	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
H3L91_RS08475	ENOG4105VTW	prevent-host-death family
H3L91_RS08480	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
H3L91_RS08485	ENOG4105K8N	protein family UPF0079, ATPase
H3L91_RS08490	ENOG4105DSY	exodeoxyribonuclease V, gamma
H3L91_RS08510	ENOG4105E6M	Sulphatase-modifying factor protein
H3L91_RS08520	ENOG4105CEI	nitrite reductase
H3L91_RS08545	ENOG4107QN2	dihydrolipoyl dehydrogenase
H3L91_RS08550	ENOG4105C7S	Dehydrogenase
H3L91_RS08555	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
H3L91_RS08560	ENOG4105BZN	citrate synthase
H3L91_RS08565	ENOG410681N	tpr repeat protein
H3L91_RS08570	ENOG4105E33	succinate dehydrogenase
H3L91_RS08600	ENOG4105CVE	Lytic murein transglycosylase
H3L91_RS08610	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
H3L91_RS08620	ENOG4105VIE	preprotein translocase, subunit YajC
H3L91_RS08625	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H3L91_RS08630	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H3L91_RS08635	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
H3L91_RS08645	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
H3L91_RS08650	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
H3L91_RS08655	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3L91_RS08675	ENOG4105CX6	glutaminyL-tRNA synthetase
H3L91_RS08680	ENOG4105D01	(LipO)protein
H3L91_RS08685	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
H3L91_RS08705	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L91_RS08745	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H3L91_RS08750	ENOG4105E9Q	Acyl-transferase
H3L91_RS08755	ENOG4105K8R	UPF0145 protein
H3L91_RS08775	ENOG41090R7	Ferric uptake
H3L91_RS08790	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
H3L91_RS08805	ENOG4108UJU	UPF0301 protein
H3L91_RS08810	ENOG4105CDY	transcriptional regulatory protein
H3L91_RS08825	ENOG4107QK7	reductase
H3L91_RS08830	ENOG4108V1T	peptidylprolyl cis-trans isomerase
H3L91_RS08845	ENOG4105KUZ	arsenate reductase
H3L91_RS08855	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
H3L91_RS08895	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
H3L91_RS08905	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
H3L91_RS08920	ENOG4105C25	Primosomal protein n'
H3L91_RS08965	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
H3L91_RS08975	ENOG4105ETU	transcriptional activator (TenA
H3L91_RS08985	ENOG4105F2I	Transposase
H3L91_RS08990	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3L91_RS09010	ENOG4108IJ6	ABC transporter
H3L91_RS09015	ENOG4105ECW	sulfate abc transporter
H3L91_RS09020	ENOG4108I5D	sulfate abc transporter
H3L91_RS09040	ENOG4105C26	Dehydrogenase
H3L91_RS09050	ENOG4105K4H	Nlp p60 protein
H3L91_RS09070	ENOG4105CUT	histidyl-tRNA synthetase
H3L91_RS09105	ENOG4105D6Z	AFG1 family ATPase
H3L91_RS09115	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
H3L91_RS09125	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
H3L91_RS09140	ENOG4105CHV	Transcription elongation factor NusA
H3L91_RS09150	ENOG4105CNU	cell division protein FtsK
H3L91_RS09155	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
H3L91_RS09180	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
H3L91_RS09190	ENOG4105CHM	Aminotransferase
H3L91_RS09195	ENOG4105F2I	Transposase
H3L91_RS09215	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3L91_RS09220	ENOG4105EAC	phosphoserine phosphatase
H3L91_RS09230	ENOG4105HBR	Rna-binding protein
H3L91_RS09240	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H3L91_RS09250	ENOG4105MJ9	esterase
H3L91_RS09255	ENOG4105D4P	Coproporphyrinogen iii oxidase
H3L91_RS09265	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
H3L91_RS09275	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
H3L91_RS09295	ENOG4105EI2	Pseudouridine synthase
H3L91_RS09300	ENOG4105C03	ribonuclease
H3L91_RS09310	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
H3L91_RS09325	ENOG4105K59	histidine triad (HIT) protein
H3L91_RS09330	ENOG4105C34	Pseudouridine synthase
H3L91_RS09350	ENOG4105EYA	deoxyribonuclease
H3L91_RS09355	ENOG4105D6S	protein involved in catabolism of external DNA
H3L91_RS09390	ENOG4105DS1	cytochrome b561
H3L91_RS09395	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
H3L91_RS09400	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
H3L91_RS09410	ENOG4108004	Modulates RecA activity (By similarity)
H3L91_RS09420	ENOG41079KZ	Major Facilitator Superfamily
H3L91_RS09425	ENOG4107QX8	SPFH domain, Band 7 family protein
H3L91_RS09435	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
H3L91_RS09440	ENOG4105CKI	cobalamin synthesis protein
H3L91_RS09445	ENOG4105MYN	Zinc uptake regulation protein
H3L91_RS09450	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
H3L91_RS09455	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H3L91_RS09470	ENOG4108UK5	Transposase
H3L91_RS09490	ENOG4105CJB	Exodeoxyribonuclease I
H3L91_RS09500	ENOG4105SYT	Methylenetetrahydrofolate reductase
H3L91_RS09535	ENOG4108HCJ	Hydrolase
H3L91_RS09545	ENOG4105CNM	Receptor
H3L91_RS09555	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H3L91_RS09585	ENOG4105E9H	Lytic Murein transglycosylase
H3L91_RS09660	ENOG4105KRF	dihydroneopterin aldolase
H3L91_RS09665	ENOG4105VEQ	Cold shock protein
H3L91_RS09685	ENOG4105K9H	YciI-like protein
H3L91_RS09740	ENOG4105E2X	shikimate dehydrogenase
H3L91_RS09745	ENOG4105EYM	Major Facilitator superfamily
H3L91_RS09770	ENOG4105D1H	recombination factor protein RarA
H3L91_RS09790	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
H3L91_RS09795	ENOG4105NX3	Membrane
H3L91_RS09800	ENOG4105C7N	Xanthine uracil vitamin C permease
H3L91_RS09815	ENOG4105HHA	aminodeoxychorismate lyase
H3L91_RS09820	ENOG4105C5F	glutamine synthetase
H3L91_RS09840	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
H3L91_RS09880	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H3L91_RS09935	ENOG4108K5P	(LipO)protein
H3L91_RS09960	ENOG4105C6K	Malic enzyme
H3L91_RS09965	ENOG4108UKZ	OsmC family
H3L91_RS09970	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
H3L91_RS09990	ENOG4105C1J	atp-dependent rna helicase
H3L91_RS10030	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H3L91_RS10050	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L91_RS10075	ENOG4105CZX	twitching motility protein
H3L91_RS10090	ENOG4107S74	Lysophospholipid transporter LplT
H3L91_RS10120	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
H3L91_RS10155	ENOG4108JQC	penicillin-binding protein 1A
H3L91_RS10160	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3L91_RS10165	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H3L91_RS10185	ENOG4105W0Z	cytoplasmic protein
H3L91_RS10200	ENOG4105D5T	phosphonate abc transporter
H3L91_RS10210	ENOG4105DY2	Paraquat-inducible protein b
H3L91_RS10220	ENOG4105KD1	integral membrane protein
H3L91_RS10255	ENOG4105C8J	)-transporter
H3L91_RS10280	ENOG4108HM4	ABC transporter
H3L91_RS10285	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
H3L91_RS10290	ENOG4105HDD	phospholipase
H3L91_RS10300	ENOG4108ZGU	inhibitor of vertebrate lysozyme
H3L91_RS10325	ENOG4105CD8	aminopeptidase N
H3L91_RS10345	ENOG4107S2Z	UPF0761 membrane protein
H3L91_RS10350	ENOG4105NTK	Transcriptional repressor Mpra
H3L91_RS10355	ENOG4105NSG	hemerythrin hhe cation binding domain protein
H3L91_RS10375	ENOG4105CQB	FAD linked oxidase domain protein
H3L91_RS10390	ENOG4105CEV	competence damage-inducible protein
H3L91_RS10405	ENOG4105D3Y	Na H antiporter
H3L91_RS10420	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
H3L91_RS10430	ENOG41082IR	Excinuclease ABC C subunit domain protein
H3L91_RS10450	ENOG4105EW9	transcriptional regulator AsnC family
H3L91_RS10465	ENOG4105CR8	Transcriptional regulator
H3L91_RS10470	ENOG4105CKW	Inner membrane protein yedI
H3L91_RS10485	ENOG4105CSA	Coproporphyrinogen iii oxidase
H3L91_RS10505	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
H3L91_RS10510	ENOG4105BZU	Histidine kinase
H3L91_RS10535	ENOG4105F7F	Chaperone
H3L91_RS10580	ENOG4105CGK	Exodeoxyribonuclease III
H3L91_RS10600	ENOG4105C7B	Threonine dehydratase
H3L91_RS10605	ENOG4105DZ1	carboxypeptidase
H3L91_RS10620	ENOG4105EEI	dihydropteroate synthase
H3L91_RS10635	ENOG4108VD1	dedA family
H3L91_RS10695	ENOG4105CQ7	ATP-dependent helicase
H3L91_RS10705	ENOG4108UK5	Transposase
H3L91_RS10710	ENOG4105CQ7	ATP-dependent helicase
H3L91_RS10710	ENOG4105CQ7	ATP-dependent helicase
H3L91_RS10730	ENOG4105EKT	)-iron permease
H3L91_RS10735	ENOG410650H	(LipO)protein
H3L91_RS10765	ENOG4105K4H	Nlp p60 protein
H3L91_RS10785	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
H3L91_RS10790	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
H3L91_RS10795	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H3L91_RS10805	ENOG4107QQG	Dehydrogenase
H3L91_RS10810	ENOG4105D7W	serine acetyltransferase
H3L91_RS10820	ENOG4105DHJ	ABC, transporter
H3L91_RS10835	ENOG4105CY3	ABC transporter, permease
H3L91_RS10840	ENOG4107PE3	Mammalian cell entry related domain protein
H3L91_RS10865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H3L91_RS10870	ENOG4107TUY	Histidine kinase
H3L91_RS10895	ENOG4108TGP	Thioesterase superfamily protein
H3L91_RS10905	ENOG4105CRE	cytochrome C
H3L91_RS10910	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
H3L91_RS10960	ENOG4105FE1	phytoene synthase
H3L91_RS10965	ENOG4107RZC	phospholipase d
H3L91_RS11000	ENOG4105F8C	transglutaminase domain-containing protein
H3L91_RS11010	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H3L91_RS11040	ENOG4105C5Q	Transcriptional regulator
H3L91_RS11060	ENOG4105E0A	ABC, transporter
H3L91_RS11065	ENOG4105J76	Periplasmic binding protein
H3L91_RS11070	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
H3L91_RS11075	ENOG4108V1U	phospholipid-binding protein
H3L91_RS11105	ENOG4107QHF	type ii secretion system protein e
H3L91_RS11150	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
H3L91_RS11225	ENOG4105E4C	Lytic transglycosylase catalytic
H3L91_RS11230	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H3L91_RS11420	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
H3L91_RS11425	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
H3L91_RS11435	ENOG4105CP2	von willebrand factor, type a
H3L91_RS11470	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H3L91_RS11480	ENOG4108IUZ	ABC transporter
H3L91_RS11485	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3L91_RS11490	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
H3L91_RS11500	ENOG4108ZG0	Ompa motb domain protein
H3L91_RS11535	ENOG4105C6T	cysteine synthase
H3L91_RS11550	ENOG4105Z2P	Protein of unknown function (DUF465)
H3L91_RS11555	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
H3L91_RS11620	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
H3L91_RS11635	ENOG4105ECX	polysaccharide export
H3L91_RS11675	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
H3L91_RS11705	ENOG4105D06	uba thif-type nad fad binding protein
H3L91_RS11710	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
H3L91_RS11720	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H3L91_RS11725	ENOG4105I08	Pseudouridine synthase
H3L91_RS11735	ENOG4107RZZ	dna polymerase iii epsilon subunit
H3L91_RS11750	ENOG4105C8J	)-transporter
H3L91_RS11765	ENOG4105D4P	Coproporphyrinogen iii oxidase
H3L91_RS11775	ENOG4107R11	Transcriptional regulator
H3L91_RS11785	ENOG4105UYK	outer membrane protein a
H3L91_RS11790	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
H3L91_RS11815	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
H3L91_RS11820	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
H3L91_RS11825	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
H3L91_RS11865	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
H3L91_RS11905	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H3L91_RS11910	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
H3L91_RS11930	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
H3L91_RS11935	ENOG4105CB5	ATP-dependent DNA helicase recG
H3L91_RS11980	ENOG4108JU5	Magnesium and cobalt efflux protein
H3L91_RS11985	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
H3L91_RS11995	ENOG4108JUA	Transcriptional regulator
H3L91_RS12085	ENOG4105E5Q	amino acid AbC transporter
H3L91_RS12105	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
H3L91_RS12110	ENOG4105BZS	acriflavin resistance protein
H3L91_RS12115	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
H3L91_RS12125	ENOG4105Q26	Siderophore-interacting protein
H3L91_RS12145	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)