locus-tag	class	description
H3L91_RS00025	COG0142	geranyltranstransferase activity
H3L91_RS00115	COG2819	hydrolase of the alpha beta superfamily
H3L91_RS00120	COG1970	mechanosensitive ion channel activity
H3L91_RS00125	COG3676	manually curated
H3L91_RS00145	COG0612	Peptidase, M16
H3L91_RS00160	COG0739	heme binding
H3L91_RS00170	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H3L91_RS00175	COG2837	iron assimilation
H3L91_RS00190	COG0613	PHP domain protein
H3L91_RS00200	COG2259	Doxx family
H3L91_RS00255	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H3L91_RS00260	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
H3L91_RS00290	COG0697	spore germination
H3L91_RS00295	COG2832	Protein of unknown function (DUF454)
H3L91_RS00320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H3L91_RS00330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3L91_RS00335	COG1126	abc transporter atp-binding protein
H3L91_RS00350	COG0728	peptidoglycan biosynthetic process
H3L91_RS00385	COG1538	Outer membrane efflux protein
H3L91_RS00445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H3L91_RS00480	COG2884	Cell division ATP-binding protein ftsE
H3L91_RS00500	COG0583	DNA-binding transcription factor activity
H3L91_RS00505	COG0799	negative regulation of ribosome biogenesis
H3L91_RS00510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H3L91_RS00515	COG2239	Acts as a magnesium transporter
H3L91_RS00535	COG1595	DNA-templated transcription, initiation
H3L91_RS00540	COG3219	Protein conserved in bacteria
H3L91_RS00555	COG2259	Doxx family
H3L91_RS00580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H3L91_RS00585	COG0483	inositol monophosphate 1-phosphatase activity
H3L91_RS00620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H3L91_RS00640	COG0471	metal ion transport
H3L91_RS00645	COG1187	pseudouridine synthase activity
H3L91_RS00695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H3L91_RS00700	COG1289	transmembrane transporter activity
H3L91_RS00710	COG3738	Protein conserved in bacteria
H3L91_RS00735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H3L91_RS00765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H3L91_RS00775	COG1505	serine-type exopeptidase activity
H3L91_RS00805	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H3L91_RS00810	COG0431	NADPH-dependent FMN reductase
H3L91_RS00820	COG0582	viral genome integration into host DNA
H3L91_RS00875	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H3L91_RS00900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H3L91_RS00905	COG1739	Uncharacterized protein family UPF0029
H3L91_RS00920	COG0859	PFAM glycosyl transferase family 9
H3L91_RS00925	COG1335	isochorismatase
H3L91_RS00945	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H3L91_RS01000	COG1247	-acetyltransferase
H3L91_RS01035	COG4178	(ABC) transporter
H3L91_RS01055	COG0616	signal peptide processing
H3L91_RS01055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H3L91_RS01060	COG1611	Belongs to the LOG family
H3L91_RS01065	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H3L91_RS01075	COG0583	DNA-binding transcription factor activity
H3L91_RS01130	COG0179	Fumarylacetoacetate (FAA) hydrolase
H3L91_RS01135	COG1214	PFAM Peptidase M22, glycoprotease
H3L91_RS01140	COG0456	acetyltransferase
H3L91_RS01150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H3L91_RS01155	COG1027	Aspartate ammonia-lyase
H3L91_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
H3L91_RS01195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H3L91_RS01220	COG1215	transferase activity, transferring glycosyl groups
H3L91_RS01230	COG0824	Thioesterase
H3L91_RS01240	COG0196	riboflavin kinase activity
H3L91_RS01270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H3L91_RS01335	COG4166	transmembrane transport
H3L91_RS01345	COG4773	Receptor
H3L91_RS01370	COG1114	Component of the transport system for branched-chain amino acids
H3L91_RS01375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H3L91_RS01385	COG2999	glutathione oxidoreductase activity
H3L91_RS01390	COG0557	exoribonuclease II activity
H3L91_RS01400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H3L91_RS01445	COG0288	reversible hydration of carbon dioxide
H3L91_RS01460	COG0406	alpha-ribazole phosphatase activity
H3L91_RS01470	COG1115	amino acid carrier protein
H3L91_RS01475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H3L91_RS01475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H3L91_RS01500	COG0024	Methionine aminopeptidase
H3L91_RS01540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H3L91_RS01545	COG0861	Integral membrane protein TerC family
H3L91_RS01550	COG2969	positive regulation of protein catabolic process
H3L91_RS01555	COG0625	glutathione transferase activity
H3L91_RS01560	COG2857	Cytochrome c1
H3L91_RS01565	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H3L91_RS01570	COG0723	plastoquinol--plastocyanin reductase activity
H3L91_RS01580	COG0339	signal peptide processing
H3L91_RS01595	COG1199	ATP-dependent helicase activity
H3L91_RS01600	COG2027	D-alanyl-D-alanine carboxypeptidase
H3L91_RS01605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H3L91_RS01640	COG0142	geranyltranstransferase activity
H3L91_RS01655	COG0583	DNA-binding transcription factor activity
H3L91_RS01670	COG1192	Involved in chromosome partitioning
H3L91_RS01675	COG1733	regulation of RNA biosynthetic process
H3L91_RS01680	COG0300	oxidoreductase activity
H3L91_RS01735	COG0312	modulator of DNA gyrase
H3L91_RS01755	COG0356	it plays a direct role in the translocation of protons across the membrane
H3L91_RS01940	COG0200	Binds to the 23S rRNA
H3L91_RS01945	COG0201	protein transport
H3L91_RS01955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H3L91_RS02010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H3L91_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
H3L91_RS02040	COG2153	protein acetylation
H3L91_RS02100	COG0210	DNA helicase
H3L91_RS02105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H3L91_RS02110	COG3104	oligopeptide transport
H3L91_RS02170	COG3278	Belongs to the heme-copper respiratory oxidase family
H3L91_RS02185	COG2010	Cytochrome c
H3L91_RS02190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H3L91_RS02210	COG3977	Valine--pyruvate aminotransferase
H3L91_RS02215	COG2119	membrane
H3L91_RS02255	COG1132	(ABC) transporter
H3L91_RS02260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H3L91_RS02260	COG0758	DNA mediated transformation
H3L91_RS02280	COG0742	ribosomal rna small subunit methyltransferase
H3L91_RS02285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H3L91_RS02355	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H3L91_RS02375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H3L91_RS02375	COG0678	peroxiredoxin activity
H3L91_RS02380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H3L91_RS02400	COG1040	competence protein
H3L91_RS02405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H3L91_RS02420	COG2226	methyltransferase
H3L91_RS02450	COG3676	manually curated
H3L91_RS02475	COG2249	NAD(P)H dehydrogenase (quinone) activity
H3L91_RS02480	COG1733	regulation of RNA biosynthetic process
H3L91_RS02555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H3L91_RS02575	COG2184	nucleotidyltransferase activity
H3L91_RS02655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H3L91_RS02655	COG0517	IMP dehydrogenase activity
H3L91_RS02685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H3L91_RS02690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H3L91_RS02695	COG0789	Transcriptional regulator
H3L91_RS02705	COG0477	Major facilitator Superfamily
H3L91_RS02725	COG1773	rubredoxin
H3L91_RS02730	COG0305	Participates in initiation and elongation during chromosome replication
H3L91_RS02755	COG4969	Belongs to the N-Me-Phe pilin family
H3L91_RS02765	COG1233	COG1233 Phytoene dehydrogenase and related
H3L91_RS02805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3L91_RS02835	COG1275	C4-dicarboxylate transporter malic acid transport protein
H3L91_RS02840	COG0642	Histidine kinase
H3L91_RS02855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H3L91_RS02860	COG0803	Belongs to the bacterial solute-binding protein 9 family
H3L91_RS02865	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H3L91_RS02870	COG2011	ABC-type metal ion transport system permease component
H3L91_RS02895	COG1733	regulation of RNA biosynthetic process
H3L91_RS02900	COG0604	alcohol dehydrogenase
H3L91_RS02905	COG4975	Glucose uptake
H3L91_RS02910	COG0656	L-ascorbic acid biosynthetic process
H3L91_RS02925	COG4221	oxidoreductase activity
H3L91_RS02950	COG2201	protein-glutamate methylesterase activity
H3L91_RS02955	COG0643	Histidine kinase
H3L91_RS02955	COG2198	Histidine kinase
H3L91_RS02965	COG0438	transferase activity, transferring glycosyl groups
H3L91_RS02990	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H3L91_RS02995	COG0732	type I restriction modification DNA specificity domain
H3L91_RS03000	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H3L91_RS03045	COG3245	cytochrome
H3L91_RS03055	COG0028	Belongs to the TPP enzyme family
H3L91_RS03060	COG0440	acetolactate synthase activity
H3L91_RS03065	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H3L91_RS03075	COG2204	response regulator
H3L91_RS03080	COG5000	phosphorelay sensor kinase activity
H3L91_RS03115	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H3L91_RS03135	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H3L91_RS03145	COG1034	ATP synthesis coupled electron transport
H3L91_RS03190	COG1605	Chorismate mutase
H3L91_RS03190	COG0287	Prephenate dehydrogenase
H3L91_RS03230	COG0204	Acyl-transferase
H3L91_RS03235	COG2814	Major facilitator Superfamily
H3L91_RS03250	COG2608	mercury ion transmembrane transporter activity
H3L91_RS03255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H3L91_RS03260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3L91_RS03285	COG0012	GTP binding
H3L91_RS03305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H3L91_RS03315	COG0842	Transport permease protein
H3L91_RS03315	COG1129	ABC transporter
H3L91_RS03325	COG1966	Carbon starvation protein
H3L91_RS03350	COG0285	dihydrofolate synthase activity
H3L91_RS03355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H3L91_RS03380	COG0582	viral genome integration into host DNA
H3L91_RS03555	COG1783	phage Terminase large subunit
H3L91_RS03565	COG2369	cell adhesion
H3L91_RS03670	COG3041	Addiction module toxin RelE StbE family
H3L91_RS03745	COG3646	Phage regulatory protein
H3L91_RS03780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H3L91_RS03830	COG0575	Belongs to the CDS family
H3L91_RS03850	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H3L91_RS03860	COG3012	SEC-C Motif Domain Protein
H3L91_RS03875	COG1794	racemase activity, acting on amino acids and derivatives
H3L91_RS03885	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3L91_RS03890	COG4605	iron ion homeostasis
H3L91_RS03895	COG4604	ABC transporter, ATP-binding protein
H3L91_RS03905	COG2814	Major facilitator Superfamily
H3L91_RS03915	COG0287	Prephenate dehydrogenase
H3L91_RS03925	COG1115	amino acid carrier protein
H3L91_RS03950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H3L91_RS03950	COG0302	gtp cyclohydrolase
H3L91_RS04020	COG1610	YqeY-like protein
H3L91_RS04065	COG0248	Ppx GppA phosphatase
H3L91_RS04080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H3L91_RS04085	COG1793	dna ligase
H3L91_RS04100	COG0281	malic enzyme
H3L91_RS04135	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H3L91_RS04185	COG1620	l-lactate permease
H3L91_RS04250	COG1846	Transcriptional regulator
H3L91_RS04260	COG0697	spore germination
H3L91_RS04280	COG0300	oxidoreductase activity
H3L91_RS04290	COG0494	nUDIX hydrolase
H3L91_RS04295	COG0741	lytic transglycosylase activity
H3L91_RS04395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H3L91_RS04485	COG5301	cellulose 1,4-beta-cellobiosidase activity
H3L91_RS04530	COG0582	viral genome integration into host DNA
H3L91_RS04570	COG1737	Transcriptional regulator
H3L91_RS04570	COG0837	glucose binding
H3L91_RS04610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H3L91_RS04620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H3L91_RS04625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H3L91_RS04630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H3L91_RS04660	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H3L91_RS04705	COG0859	PFAM glycosyl transferase family 9
H3L91_RS04780	COG0492	ferredoxin-NADP+ reductase activity
H3L91_RS04785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H3L91_RS04790	COG0586	Pfam SNARE associated Golgi protein
H3L91_RS04795	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H3L91_RS04805	COG1324	tolerance protein
H3L91_RS04895	COG0681	Belongs to the peptidase S26 family
H3L91_RS04960	COG0729	surface antigen
H3L91_RS04970	COG3279	Response regulator of the LytR AlgR family
H3L91_RS04975	COG0626	cystathionine gamma-synthase activity
H3L91_RS04980	COG1530	ribonuclease E activity
H3L91_RS04990	COG3787	Belongs to the UPF0306 family
H3L91_RS05005	COG0488	(ABC) transporter
H3L91_RS05030	COG0730	response to heat
H3L91_RS05035	COG2995	paraquat-inducible protein a
H3L91_RS05045	COG2895	sulfate adenylyltransferase (ATP) activity
H3L91_RS05050	COG0175	sulfate reduction
H3L91_RS05085	COG0633	Ferredoxin
H3L91_RS05105	COG3275	phosphorelay sensor kinase activity
H3L91_RS05115	COG0494	nUDIX hydrolase
H3L91_RS05120	COG3264	Mechanosensitive ion channel
H3L91_RS05120	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H3L91_RS05135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3L91_RS05145	COG1538	Outer membrane efflux protein
H3L91_RS05150	COG2070	2-Nitropropane dioxygenase
H3L91_RS05155	COG2267	carboxylic ester hydrolase activity
H3L91_RS05180	COG2755	lipolytic protein G-D-S-L family
H3L91_RS05190	COG0307	riboflavin synthase, alpha
H3L91_RS05220	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
H3L91_RS05220	COG0778	Nitroreductase
H3L91_RS05265	COG0084	hydrolase, TatD family'
H3L91_RS05290	COG3045	CreA protein
H3L91_RS05300	COG1253	flavin adenine dinucleotide binding
H3L91_RS05325	COG2975	iron-sulfur cluster assembly
H3L91_RS05365	COG0822	iron-sulfur transferase activity
H3L91_RS05385	COG1304	FMN binding
H3L91_RS05405	COG2814	Major facilitator Superfamily
H3L91_RS05410	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H3L91_RS05470	COG1064	alcohol dehydrogenase
H3L91_RS05485	COG2226	methyltransferase
H3L91_RS05495	COG0720	synthase
H3L91_RS05500	COG3759	membrane
H3L91_RS05515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H3L91_RS05565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H3L91_RS05605	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H3L91_RS05605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H3L91_RS05625	COG1959	2 iron, 2 sulfur cluster binding
H3L91_RS05665	COG4174	ABC transporter (Permease)
H3L91_RS05700	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H3L91_RS05710	COG0471	metal ion transport
H3L91_RS05715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H3L91_RS05720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H3L91_RS05800	COG0617	tRNA 3'-terminal CCA addition
H3L91_RS05825	COG0497	DNA recombination
H3L91_RS05835	COG1994	Peptidase M50
H3L91_RS05845	COG0009	L-threonylcarbamoyladenylate synthase
H3L91_RS05890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H3L91_RS05910	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H3L91_RS05935	COG0786	glutamate:sodium symporter activity
H3L91_RS06000	COG0582	viral genome integration into host DNA
H3L91_RS06030	COG4239	(ABC) transporter, permease
H3L91_RS06040	COG2453	phosphatase
H3L91_RS06040	COG0671	phosphoesterase, PA-phosphatase related
H3L91_RS06045	COG1763	Mo-molybdopterin cofactor biosynthetic process
H3L91_RS06050	COG0708	Exodeoxyribonuclease III
H3L91_RS06060	COG1012	belongs to the aldehyde dehydrogenase family
H3L91_RS06145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H3L91_RS06155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H3L91_RS06165	COG0508	dehydrogenase complex catalyzes the overall conversion of
H3L91_RS06170	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H3L91_RS06200	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H3L91_RS06210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H3L91_RS06245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H3L91_RS06265	COG0842	Transport permease protein
H3L91_RS06275	COG0569	domain protein
H3L91_RS06280	COG1561	YicC-like family, N-terminal region
H3L91_RS06370	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
H3L91_RS06395	COG1560	Kdo2-lipid A biosynthetic process
H3L91_RS06405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H3L91_RS06415	COG0582	viral genome integration into host DNA
H3L91_RS06470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H3L91_RS06480	COG1028	Short-chain dehydrogenase reductase Sdr
H3L91_RS06485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H3L91_RS06490	COG2233	PERMEase
H3L91_RS06510	COG0318	PFAM AMP-dependent synthetase and ligase
H3L91_RS06515	COG3263	regulation of cellular component size
H3L91_RS06525	COG1116	anion transmembrane transporter activity
H3L91_RS06550	COG0778	Nitroreductase
H3L91_RS06560	COG3042	response to heat
H3L91_RS06565	COG0590	tRNA wobble adenosine to inosine editing
H3L91_RS06570	COG0772	Belongs to the SEDS family
H3L91_RS06575	COG0768	penicillin binding
H3L91_RS06590	COG1077	Cell shape determining protein MreB Mrl
H3L91_RS06620	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H3L91_RS06635	COG2990	Protein conserved in bacteria
H3L91_RS06670	COG3676	manually curated
H3L91_RS06680	COG3385	transposase activity
H3L91_RS06690	COG2878	Part of a membrane complex involved in electron transport
H3L91_RS06700	COG3676	manually curated
H3L91_RS06705	COG3385	transposase activity
H3L91_RS06710	COG0436	Aminotransferase
H3L91_RS06780	COG0314	molybdopterin synthase activity
H3L91_RS06790	COG0315	cyclic pyranopterin monophosphate synthase activity
H3L91_RS06795	COG0778	Nitroreductase
H3L91_RS06810	COG2223	nitrite transmembrane transporter activity
H3L91_RS06815	COG0303	'Molybdopterin
H3L91_RS06820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H3L91_RS06825	COG0521	Mo-molybdopterin cofactor biosynthetic process
H3L91_RS06830	COG0746	molybdenum cofactor guanylyltransferase activity
H3L91_RS06840	COG3842	ATPase activity
H3L91_RS06845	COG4149	molybdate abc transporter
H3L91_RS06855	COG0725	ABC transporter, periplasmic molybdate-binding protein
H3L91_RS06860	COG2181	nitrate reductase activity
H3L91_RS06865	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H3L91_RS06870	COG1140	nitrate reductase beta subunit
H3L91_RS06880	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H3L91_RS06895	COG1120	ATPase activity
H3L91_RS06900	COG2249	NAD(P)H dehydrogenase (quinone) activity
H3L91_RS06910	COG0644	oxidoreductase
H3L91_RS06910	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H3L91_RS06985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H3L91_RS07010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H3L91_RS07030	COG2217	Heavy metal translocating P-type atpase
H3L91_RS07045	COG3647	Membrane
H3L91_RS07055	COG0513	Belongs to the DEAD box helicase family
H3L91_RS07060	COG4172	Belongs to the ABC transporter superfamily
H3L91_RS07065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H3L91_RS07070	COG0601	transmembrane transport
H3L91_RS07110	COG0697	spore germination
H3L91_RS07115	COG2866	Carboxypeptidase
H3L91_RS07125	COG0039	L-malate dehydrogenase activity
H3L91_RS07145	COG0697	spore germination
H3L91_RS07155	COG4589	Belongs to the CDS family
H3L91_RS07195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H3L91_RS07225	COG0653	protein targeting
H3L91_RS07240	COG2095	MarC family integral membrane protein
H3L91_RS07250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H3L91_RS07270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H3L91_RS07275	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H3L91_RS07280	COG1183	phosphatidylcholine synthase activity
H3L91_RS07310	COG1702	phosphate starvation-inducible protein PhoH
H3L91_RS07320	COG1074	ATP-dependent DNA helicase activity
H3L91_RS07330	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H3L91_RS07335	COG1619	proteins homologs of microcin C7 resistance protein MccF
H3L91_RS07345	COG1368	sulfuric ester hydrolase activity
H3L91_RS07390	COG1408	metallophosphoesterase
H3L91_RS07395	COG0783	Belongs to the Dps family
H3L91_RS07400	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H3L91_RS07400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H3L91_RS07415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H3L91_RS07420	COG2321	neutral zinc metallopeptidase
H3L91_RS07430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H3L91_RS07440	COG0433	COG0433 Predicted ATPase
H3L91_RS07445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H3L91_RS07465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H3L91_RS07480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H3L91_RS07485	COG4172	Belongs to the ABC transporter superfamily
H3L91_RS07525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3L91_RS07535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H3L91_RS07555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H3L91_RS07565	COG0280	phosphate acetyltransferase
H3L91_RS07565	COG0281	malic enzyme
H3L91_RS07575	COG0628	permease
H3L91_RS07580	COG3161	chorismate lyase activity
H3L91_RS07585	COG0463	Glycosyl transferase, family 2
H3L91_RS07595	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H3L91_RS07625	COG1253	flavin adenine dinucleotide binding
H3L91_RS07630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3L91_RS07650	COG3842	ATPase activity
H3L91_RS07655	COG1176	ABC-type spermidine putrescine transport system, permease component I
H3L91_RS07660	COG1177	transmembrane transport
H3L91_RS07675	COG3676	manually curated
H3L91_RS07680	COG4774	siderophore transport
H3L91_RS07695	COG0247	lactate metabolic process
H3L91_RS07705	COG1139	Iron-sulfur cluster binding protein
H3L91_RS07715	COG1943	Transposase
H3L91_RS07760	COG0583	DNA-binding transcription factor activity
H3L91_RS07770	COG2301	Belongs to the HpcH HpaI aldolase family
H3L91_RS07790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H3L91_RS07800	COG3568	Endonuclease Exonuclease Phosphatase
H3L91_RS07860	COG3850	Histidine kinase
H3L91_RS07865	COG2197	response regulator
H3L91_RS07890	COG0793	Belongs to the peptidase S41A family
H3L91_RS07905	COG0564	pseudouridine synthase activity
H3L91_RS07910	COG0252	asparaginase activity
H3L91_RS07920	COG0488	(ABC) transporter
H3L91_RS07950	COG2860	membrane
H3L91_RS07980	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H3L91_RS07985	COG3154	lipid carrier protein
H3L91_RS07990	COG0826	peptidase U32
H3L91_RS07995	COG0826	peptidase U32
H3L91_RS08025	COG2233	PERMEase
H3L91_RS08040	COG2814	Major facilitator Superfamily
H3L91_RS08055	COG4178	(ABC) transporter
H3L91_RS08085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H3L91_RS08110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H3L91_RS08135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H3L91_RS08140	COG1132	(ABC) transporter
H3L91_RS08335	COG2932	Transcriptional regulator
H3L91_RS08395	COG4373	Mu-like prophage FluMu protein gp28
H3L91_RS08400	COG4383	Mu-like prophage protein gp29
H3L91_RS08405	COG2369	cell adhesion
H3L91_RS08410	COG5005	Phage virion morphogenesis
H3L91_RS08420	COG3385	transposase activity
H3L91_RS08430	COG0121	glutamine amidotransferase
H3L91_RS08435	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H3L91_RS08440	COG1448	Aminotransferase
H3L91_RS08445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H3L91_RS08450	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H3L91_RS08455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H3L91_RS08470	COG4115	mRNA cleavage
H3L91_RS08475	COG2161	toxin-antitoxin pair type II binding
H3L91_RS08485	COG0802	atpase or kinase
H3L91_RS08490	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H3L91_RS08510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H3L91_RS08530	COG3256	nitric oxide reductase
H3L91_RS08545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H3L91_RS08550	COG0508	dehydrogenase complex catalyzes the overall conversion of
H3L91_RS08555	COG0567	Dehydrogenase, E1 component
H3L91_RS08565	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H3L91_RS08570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H3L91_RS08575	COG1053	succinate dehydrogenase
H3L91_RS08600	COG2951	lytic endotransglycosylase activity
H3L91_RS08610	COG0756	dUTP diphosphatase activity
H3L91_RS08620	COG1862	Preprotein translocase
H3L91_RS08625	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H3L91_RS08630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H3L91_RS08635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3L91_RS08650	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H3L91_RS08680	COG1464	Belongs to the NlpA lipoprotein family
H3L91_RS08685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H3L91_RS08745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H3L91_RS08745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H3L91_RS08755	COG0393	Putative heavy-metal-binding
H3L91_RS08760	COG0393	Putative heavy-metal-binding
H3L91_RS08790	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H3L91_RS08845	COG1393	Belongs to the ArsC family
H3L91_RS08855	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H3L91_RS08920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H3L91_RS08965	COG0415	Belongs to the DNA photolyase family
H3L91_RS08975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H3L91_RS09015	COG4208	sulfate ABC transporter
H3L91_RS09040	COG1012	belongs to the aldehyde dehydrogenase family
H3L91_RS09050	COG0791	NLP P60 protein
H3L91_RS09105	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H3L91_RS09150	COG1674	ftsk spoiiie
H3L91_RS09155	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H3L91_RS09190	COG0436	Aminotransferase
H3L91_RS09220	COG0560	Phosphoserine phosphatase
H3L91_RS09230	COG1534	Rna-binding protein
H3L91_RS09240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H3L91_RS09245	COG0789	Transcriptional regulator
H3L91_RS09250	COG3545	Serine hydrolase
H3L91_RS09265	COG1519	Transferase
H3L91_RS09275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H3L91_RS09300	COG1530	ribonuclease E activity
H3L91_RS09310	COG0805	protein transport
H3L91_RS09345	COG0351	phosphomethylpyrimidine kinase
H3L91_RS09350	COG0084	hydrolase, TatD family'
H3L91_RS09355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H3L91_RS09390	COG3038	cytochrome b561
H3L91_RS09395	COG1854	S-ribosylhomocysteine lyase activity
H3L91_RS09400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H3L91_RS09420	COG0477	Major facilitator Superfamily
H3L91_RS09425	COG0330	HflC and HflK could
H3L91_RS09440	COG0523	cobalamin synthesis protein
H3L91_RS09445	COG0735	belongs to the Fur family
H3L91_RS09470	COG1943	Transposase
H3L91_RS09490	COG2925	Exonuclease
H3L91_RS09535	COG0561	phosphatase activity
H3L91_RS09555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H3L91_RS09585	COG1388	LysM domain
H3L91_RS09585	COG0741	lytic transglycosylase activity
H3L91_RS09660	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H3L91_RS09665	COG1278	Cold shock
H3L91_RS09685	COG2350	Protein conserved in bacteria
H3L91_RS09705	COG3676	manually curated
H3L91_RS09745	COG2211	Major facilitator Superfamily
H3L91_RS09770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H3L91_RS09790	COG0829	nickel cation binding
H3L91_RS09795	COG3739	integral membrane protein
H3L91_RS09800	COG2252	PERMEase
H3L91_RS09815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H3L91_RS09880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H3L91_RS09935	COG4942	peptidase
H3L91_RS09965	COG1765	OsmC-like protein
H3L91_RS09970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H3L91_RS09990	COG0513	Belongs to the DEAD box helicase family
H3L91_RS10030	COG0514	ATP-dependent DNA helicase (RecQ)
H3L91_RS10035	COG1063	alcohol dehydrogenase
H3L91_RS10065	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H3L91_RS10175	COG3385	transposase activity
H3L91_RS10200	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H3L91_RS10210	COG3008	intermembrane lipid transfer
H3L91_RS10210	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H3L91_RS10255	COG0733	neurotransmitter:sodium symporter activity
H3L91_RS10285	COG0268	Binds directly to 16S ribosomal RNA
H3L91_RS10325	COG0308	aminopeptidase N
H3L91_RS10350	COG1846	Transcriptional regulator
H3L91_RS10355	COG3945	hemerythrin HHE cation binding domain
H3L91_RS10375	COG0277	FAD linked oxidase domain protein
H3L91_RS10390	COG1058	Belongs to the CinA family
H3L91_RS10390	COG1546	Belongs to the CinA family
H3L91_RS10405	COG2056	Na+-H+ antiporter family
H3L91_RS10420	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H3L91_RS10430	COG2827	Endonuclease containing a URI domain
H3L91_RS10465	COG0583	DNA-binding transcription factor activity
H3L91_RS10470	COG2354	Protein conserved in bacteria
H3L91_RS10475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H3L91_RS10485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H3L91_RS10505	COG0745	RESPONSE REGULATOR receiver
H3L91_RS10510	COG5002	protein histidine kinase activity
H3L91_RS10535	COG0443	Heat shock 70 kDa protein
H3L91_RS10580	COG0708	Exodeoxyribonuclease III
H3L91_RS10600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H3L91_RS10605	COG1686	Belongs to the peptidase S11 family
H3L91_RS10635	COG0586	Pfam SNARE associated Golgi protein
H3L91_RS10695	COG1643	Atp-dependent helicase
H3L91_RS10705	COG1943	Transposase
H3L91_RS10710	COG1643	Atp-dependent helicase
H3L91_RS10710	COG1643	Atp-dependent helicase
H3L91_RS10730	COG0672	)-iron permease
H3L91_RS10765	COG0791	NLP P60 protein
H3L91_RS10785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H3L91_RS10790	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H3L91_RS10795	COG0519	Catalyzes the synthesis of GMP from XMP
H3L91_RS10800	COG0673	inositol 2-dehydrogenase activity
H3L91_RS10810	COG1045	serine acetyltransferase
H3L91_RS10820	COG1127	ABC transporter
H3L91_RS10835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H3L91_RS10840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H3L91_RS10885	COG2954	triphosphatase activity
H3L91_RS10895	COG0824	Thioesterase
H3L91_RS10905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H3L91_RS10910	COG1333	cytochrome c biogenesis protein
H3L91_RS10960	COG1562	ergosterol biosynthetic process
H3L91_RS10965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H3L91_RS11010	COG0714	Associated with various cellular activities
H3L91_RS11045	COG1380	Effector of murein hydrolase LrgA
H3L91_RS11060	COG1120	ATPase activity
H3L91_RS11065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H3L91_RS11075	COG1881	PFAM PEBP family protein
H3L91_RS11105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H3L91_RS11150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H3L91_RS11175	COG0681	Belongs to the peptidase S26 family
H3L91_RS11225	COG0741	lytic transglycosylase activity
H3L91_RS11225	COG1196	nuclear chromosome segregation
H3L91_RS11225	COG0739	heme binding
H3L91_RS11230	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H3L91_RS11245	COG1487	ribonuclease activity
H3L91_RS11280	COG3621	Patatin-like phospholipase
H3L91_RS11420	COG1192	Involved in chromosome partitioning
H3L91_RS11425	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H3L91_RS11435	COG2304	oxidoreductase activity
H3L91_RS11450	COG1505	serine-type exopeptidase activity
H3L91_RS11480	COG1137	ATPase activity
H3L91_RS11485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H3L91_RS11500	COG2885	chlorophyll binding
H3L91_RS11550	COG2841	Protein conserved in bacteria
H3L91_RS11555	COG1091	dTDP-4-dehydrorhamnose reductase activity
H3L91_RS11605	COG1999	signal sequence binding
H3L91_RS11675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H3L91_RS11705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H3L91_RS11710	COG1196	nuclear chromosome segregation
H3L91_RS11720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H3L91_RS11725	COG1187	pseudouridine synthase activity
H3L91_RS11750	COG0733	neurotransmitter:sodium symporter activity
H3L91_RS11765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H3L91_RS11770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H3L91_RS11775	COG0583	DNA-binding transcription factor activity
H3L91_RS11790	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H3L91_RS11865	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H3L91_RS11905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H3L91_RS11910	COG1376	ErfK ybiS ycfS ynhG family protein
H3L91_RS11930	COG0312	modulator of DNA gyrase
H3L91_RS11935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H3L91_RS12085	COG0765	amino acid transport