locus-tag	class	description
I6G71_RS00020	COG3676	manually curated
I6G71_RS00040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I6G71_RS00050	COG2954	triphosphatase activity
I6G71_RS00055	COG1981	membrane
I6G71_RS00080	COG0739	heme binding
I6G71_RS00085	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
I6G71_RS00135	COG0142	geranyltranstransferase activity
I6G71_RS00195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I6G71_RS00205	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
I6G71_RS00225	COG2350	Protein conserved in bacteria
I6G71_RS00250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I6G71_RS00275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
I6G71_RS00285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
I6G71_RS00290	COG1137	ATPase activity
I6G71_RS00315	COG2814	Major facilitator Superfamily
I6G71_RS00410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I6G71_RS00415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I6G71_RS00420	COG0583	DNA-binding transcription factor activity
I6G71_RS00430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
I6G71_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I6G71_RS00440	COG0488	(ABC) transporter
I6G71_RS00450	COG2017	converts alpha-aldose to the beta-anomer
I6G71_RS00460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6G71_RS00470	COG0798	PFAM Bile acid sodium symporter
I6G71_RS00480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6G71_RS00515	COG0640	Transcriptional regulator
I6G71_RS00520	COG0708	Exodeoxyribonuclease III
I6G71_RS00545	COG2960	long-chain fatty acid transporting porin activity
I6G71_RS00550	COG0606	chelatase, subunit chli
I6G71_RS00615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I6G71_RS00675	COG2252	PERMEase
I6G71_RS00685	COG0372	Belongs to the citrate synthase family
I6G71_RS00700	COG2828	Protein conserved in bacteria
I6G71_RS00710	COG0009	L-threonylcarbamoyladenylate synthase
I6G71_RS00715	COG1959	2 iron, 2 sulfur cluster binding
I6G71_RS00730	COG0287	Prephenate dehydrogenase
I6G71_RS00735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I6G71_RS00745	COG0697	spore germination
I6G71_RS00750	COG2814	Major facilitator Superfamily
I6G71_RS00810	COG0802	atpase or kinase
I6G71_RS00880	COG1376	ErfK ybiS ycfS ynhG family protein
I6G71_RS00885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
I6G71_RS00895	COG2830	Protein of unknown function (DUF452)
I6G71_RS00900	COG0500	methyltransferase
I6G71_RS00980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6G71_RS00985	COG1538	Outer membrane efflux protein
I6G71_RS00995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I6G71_RS01005	COG2999	glutathione oxidoreductase activity
I6G71_RS01015	COG1994	Peptidase M50
I6G71_RS01035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I6G71_RS01035	COG3453	Protein conserved in bacteria
I6G71_RS01045	COG3278	Belongs to the heme-copper respiratory oxidase family
I6G71_RS01060	COG2010	Cytochrome c
I6G71_RS01075	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
I6G71_RS01080	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
I6G71_RS01120	COG1620	l-lactate permease
I6G71_RS01135	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I6G71_RS01150	COG0733	neurotransmitter:sodium symporter activity
I6G71_RS01175	COG3676	manually curated
I6G71_RS01205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
I6G71_RS01220	COG0586	Pfam SNARE associated Golgi protein
I6G71_RS01225	COG0252	asparaginase activity
I6G71_RS01240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I6G71_RS01285	COG3245	cytochrome
I6G71_RS01325	COG3008	intermembrane lipid transfer
I6G71_RS01325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
I6G71_RS01350	COG0826	peptidase U32
I6G71_RS01355	COG0561	phosphatase activity
I6G71_RS01375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I6G71_RS01380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I6G71_RS01410	COG1596	polysaccharide export
I6G71_RS01410	COG1555	photosystem II stabilization
I6G71_RS01470	COG1115	amino acid carrier protein
I6G71_RS01475	COG1272	protein, Hemolysin III
I6G71_RS01485	COG1160	GTP binding
I6G71_RS01515	COG2194	sulfuric ester hydrolase activity
I6G71_RS01520	COG0778	Nitroreductase
I6G71_RS01535	COG1262	PFAM Formylglycine-generating sulfatase enzyme
I6G71_RS01555	COG3423	Transcriptional regulator
I6G71_RS01565	COG2842	Transposition protein
I6G71_RS01720	COG4383	Mu-like prophage protein gp29
I6G71_RS01740	COG4397	Mu-like prophage major head subunit gpT
I6G71_RS01855	COG3392	D12 class N6 adenine-specific DNA methyltransferase
I6G71_RS01865	COG1619	proteins homologs of microcin C7 resistance protein MccF
I6G71_RS01885	COG0351	phosphomethylpyrimidine kinase
I6G71_RS01905	COG0569	domain protein
I6G71_RS01910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I6G71_RS01910	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I6G71_RS01950	COG5002	protein histidine kinase activity
I6G71_RS01965	COG1002	Type II restriction enzyme, methylase subunits
I6G71_RS02000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I6G71_RS02015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I6G71_RS02075	COG2084	Dehydrogenase
I6G71_RS02105	COG1999	signal sequence binding
I6G71_RS02115	COG0028	Belongs to the TPP enzyme family
I6G71_RS02140	COG1049	propionate catabolic process, 2-methylcitrate cycle
I6G71_RS02170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I6G71_RS02180	COG1765	OsmC-like protein
I6G71_RS02185	COG1802	Transcriptional regulator
I6G71_RS02190	COG2431	L-lysine efflux transmembrane transporter activity
I6G71_RS02230	COG0318	PFAM AMP-dependent synthetase and ligase
I6G71_RS02290	COG3945	hemerythrin HHE cation binding domain
I6G71_RS02310	COG1881	PFAM PEBP family protein
I6G71_RS02315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I6G71_RS02325	COG0859	PFAM glycosyl transferase family 9
I6G71_RS02340	COG0277	FAD linked oxidase domain protein
I6G71_RS02355	COG1562	ergosterol biosynthetic process
I6G71_RS02415	COG0765	amino acid transport
I6G71_RS02445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
I6G71_RS02480	COG1966	Carbon starvation protein
I6G71_RS02505	COG1253	flavin adenine dinucleotide binding
I6G71_RS02525	COG1607	acyl-coa hydrolase
I6G71_RS02555	COG1942	4-Oxalocrotonate Tautomerase
I6G71_RS02560	COG0436	Aminotransferase
I6G71_RS02610	COG1943	Transposase
I6G71_RS02625	COG1196	nuclear chromosome segregation
I6G71_RS02625	COG0741	lytic transglycosylase activity
I6G71_RS02625	COG0739	heme binding
I6G71_RS02630	COG2814	Major facilitator Superfamily
I6G71_RS02645	COG0697	spore germination
I6G71_RS02655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I6G71_RS02660	COG0348	domain, Protein
I6G71_RS02675	COG2070	2-Nitropropane dioxygenase
I6G71_RS02715	COG0210	DNA helicase
I6G71_RS02740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
I6G71_RS02765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
I6G71_RS02770	COG1139	Iron-sulfur cluster binding protein
I6G71_RS02780	COG0247	lactate metabolic process
I6G71_RS02785	COG0477	Major facilitator Superfamily
I6G71_RS02790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6G71_RS02795	COG0791	NLP P60 protein
I6G71_RS02870	COG0513	Belongs to the DEAD box helicase family
I6G71_RS02880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I6G71_RS02895	COG1560	Kdo2-lipid A biosynthetic process
I6G71_RS02905	COG0308	aminopeptidase N
I6G71_RS02945	COG1194	a g-specific adenine glycosylase
I6G71_RS02960	COG0800	Aldolase
I6G71_RS02970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
I6G71_RS02985	COG1737	Transcriptional regulator
I6G71_RS03015	COG3676	manually curated
I6G71_RS03030	COG3036	rescue of stalled ribosome
I6G71_RS03040	COG0822	iron-sulfur transferase activity
I6G71_RS03055	COG1304	FMN binding
I6G71_RS03060	COG3421	Type III restriction
I6G71_RS03105	COG0513	Belongs to the DEAD box helicase family
I6G71_RS03125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
I6G71_RS03155	COG0543	2 iron, 2 sulfur cluster binding
I6G71_RS03155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I6G71_RS03165	COG2990	Protein conserved in bacteria
I6G71_RS03180	COG2095	MarC family integral membrane protein
I6G71_RS03185	COG1012	belongs to the aldehyde dehydrogenase family
I6G71_RS03195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
I6G71_RS03195	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
I6G71_RS03210	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
I6G71_RS03235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6G71_RS03240	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6G71_RS03245	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
I6G71_RS03255	COG0179	Fumarylacetoacetate (FAA) hydrolase
I6G71_RS03270	COG3045	CreA protein
I6G71_RS03280	COG0793	Belongs to the peptidase S41A family
I6G71_RS03300	COG3676	manually curated
I6G71_RS03320	COG2217	Heavy metal translocating P-type atpase
I6G71_RS03325	COG0492	ferredoxin-NADP+ reductase activity
I6G71_RS03355	COG0730	response to heat
I6G71_RS03360	COG1183	phosphatidylcholine synthase activity
I6G71_RS03415	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
I6G71_RS03420	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
I6G71_RS03425	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
I6G71_RS03430	COG0789	Transcriptional regulator
I6G71_RS03460	COG0733	neurotransmitter:sodium symporter activity
I6G71_RS03475	COG0741	lytic transglycosylase activity
I6G71_RS03475	COG1388	LysM domain
I6G71_RS03500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I6G71_RS03515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I6G71_RS03520	COG0633	Ferredoxin
I6G71_RS03550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
I6G71_RS03565	COG2951	lytic endotransglycosylase activity
I6G71_RS03580	COG3676	manually curated
I6G71_RS03595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I6G71_RS03600	COG0318	PFAM AMP-dependent synthetase and ligase
I6G71_RS03635	COG2608	mercury ion transmembrane transporter activity
I6G71_RS03640	COG4797	methyltransferase
I6G71_RS03640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
I6G71_RS03655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I6G71_RS03665	COG0523	cobalamin synthesis protein
I6G71_RS03670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I6G71_RS03695	COG0251	oxidation-reduction process
I6G71_RS03700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I6G71_RS03710	COG0697	spore germination
I6G71_RS03715	COG1027	Aspartate ammonia-lyase
I6G71_RS03725	COG2353	YceI-like domain
I6G71_RS03765	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
I6G71_RS03775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I6G71_RS03780	COG2217	Heavy metal translocating P-type atpase
I6G71_RS03810	COG0583	DNA-binding transcription factor activity
I6G71_RS03830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I6G71_RS03880	COG2197	response regulator
I6G71_RS03885	COG3850	Histidine kinase
I6G71_RS03895	COG0307	riboflavin synthase, alpha
I6G71_RS03910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I6G71_RS03930	COG0488	(ABC) transporter
I6G71_RS03935	COG1393	Belongs to the ArsC family
I6G71_RS03965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I6G71_RS03970	COG2890	protein-(glutamine-N5) methyltransferase activity
I6G71_RS03980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I6G71_RS04005	COG0488	(ABC) transporter
I6G71_RS04030	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
I6G71_RS04050	COG0330	HflC and HflK could
I6G71_RS04055	COG0628	permease
I6G71_RS04110	COG0557	exoribonuclease II activity
I6G71_RS04135	COG1217	gtp-binding protein TYPA
I6G71_RS04165	COG2895	sulfate adenylyltransferase (ATP) activity
I6G71_RS04200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
I6G71_RS04220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6G71_RS04235	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I6G71_RS04240	COG2975	iron-sulfur cluster assembly
I6G71_RS04250	COG0633	Ferredoxin
I6G71_RS04275	COG1562	ergosterol biosynthetic process
I6G71_RS04305	COG4178	(ABC) transporter
I6G71_RS04310	COG3392	D12 class N6 adenine-specific DNA methyltransferase
I6G71_RS04340	COG5301	cellulose 1,4-beta-cellobiosidase activity
I6G71_RS04425	COG4388	Caudovirus prohead serine protease
I6G71_RS04430	COG5005	Phage virion morphogenesis
I6G71_RS04435	COG2369	cell adhesion
I6G71_RS04440	COG4383	Mu-like prophage protein gp29
I6G71_RS04535	COG3561	AntA/AntB antirepressor
I6G71_RS04545	COG4396	Host-nuclease inhibitor protein Gam
I6G71_RS04595	COG4178	(ABC) transporter
I6G71_RS04600	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
I6G71_RS04620	COG2866	Carboxypeptidase
I6G71_RS04630	COG3012	SEC-C Motif Domain Protein
I6G71_RS04630	COG3318	Belongs to the UPF0149 family
I6G71_RS04680	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
I6G71_RS04690	COG2841	Protein conserved in bacteria
I6G71_RS04700	COG0405	Gamma-glutamyltransferase
I6G71_RS04735	COG0586	Pfam SNARE associated Golgi protein
I6G71_RS04740	COG0488	(ABC) transporter
I6G71_RS04760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
I6G71_RS04770	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
I6G71_RS04810	COG2801	Transposase and inactivated derivatives
I6G71_RS04930	COG0277	FAD linked oxidase domain protein
I6G71_RS04955	COG1773	rubredoxin
I6G71_RS05060	COG0560	Phosphoserine phosphatase
I6G71_RS05065	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
I6G71_RS05075	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
I6G71_RS05080	COG2249	NAD(P)H dehydrogenase (quinone) activity
I6G71_RS05150	COG2189	Belongs to the N(4) N(6)-methyltransferase family
I6G71_RS05160	COG1943	Transposase
I6G71_RS05180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6G71_RS05190	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6G71_RS05195	COG0567	Dehydrogenase, E1 component
I6G71_RS05210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I6G71_RS05235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
I6G71_RS05235	COG0678	peroxiredoxin activity
I6G71_RS05270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
I6G71_RS05270	COG2813	Specifically methylates the guanine in position
I6G71_RS05300	COG0590	tRNA wobble adenosine to inosine editing
I6G71_RS05315	COG2233	PERMEase
I6G71_RS05340	COG1607	acyl-coa hydrolase
I6G71_RS05345	COG4221	oxidoreductase activity
I6G71_RS05390	COG0436	Aminotransferase
I6G71_RS05430	COG0305	Participates in initiation and elongation during chromosome replication
I6G71_RS05435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
I6G71_RS05440	COG1755	Isoprenylcysteine carboxyl methyltransferase
I6G71_RS05460	COG4208	sulfate ABC transporter
I6G71_RS05470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I6G71_RS05675	COG0438	transferase activity, transferring glycosyl groups
I6G71_RS05680	COG1702	phosphate starvation-inducible protein PhoH
I6G71_RS05710	COG0312	modulator of DNA gyrase
I6G71_RS05715	COG1278	Cold shock
I6G71_RS05780	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
I6G71_RS05780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
I6G71_RS05850	COG1309	transcriptional regulator
I6G71_RS05855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I6G71_RS05870	COG1187	pseudouridine synthase activity
I6G71_RS05875	COG0778	Nitroreductase
I6G71_RS05885	COG0626	cystathionine gamma-synthase activity
I6G71_RS05905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
I6G71_RS05935	COG0471	metal ion transport
I6G71_RS05940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I6G71_RS05950	COG1126	abc transporter atp-binding protein
I6G71_RS05955	COG0765	amino acid transport
I6G71_RS05960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6G71_RS05965	COG2837	iron assimilation
I6G71_RS05970	COG1074	ATP-dependent DNA helicase activity
I6G71_RS06025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
I6G71_RS06035	COG0084	hydrolase, TatD family'
I6G71_RS06055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I6G71_RS06065	COG0681	Belongs to the peptidase S26 family
I6G71_RS06135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I6G71_RS06150	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
I6G71_RS06160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I6G71_RS06180	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
I6G71_RS06180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I6G71_RS06200	COG0497	DNA recombination
I6G71_RS06205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
I6G71_RS06210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I6G71_RS06245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I6G71_RS06245	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
I6G71_RS06340	COG3263	regulation of cellular component size
I6G71_RS06345	COG3263	regulation of cellular component size
I6G71_RS06355	COG2354	Protein conserved in bacteria
I6G71_RS06370	COG1561	YicC-like family, N-terminal region
I6G71_RS06385	COG1466	dna polymerase III delta subunit
I6G71_RS06390	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
I6G71_RS06400	COG0385	Bile acid
I6G71_RS06440	COG1126	abc transporter atp-binding protein
I6G71_RS06455	COG0285	dihydrofolate synthase activity
I6G71_RS06470	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
I6G71_RS06530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
I6G71_RS06590	COG0280	phosphate acetyltransferase
I6G71_RS06590	COG0281	malic enzyme
I6G71_RS06600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I6G71_RS06620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I6G71_RS06690	COG0494	nUDIX hydrolase
I6G71_RS06710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I6G71_RS06730	COG1178	ABC-type Fe3 transport system permease component
I6G71_RS06740	COG0857	belongs to the CobB CobQ family
I6G71_RS06740	COG0280	phosphate acetyltransferase
I6G71_RS06780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I6G71_RS06800	COG2833	Protein of unknown function (DUF455)
I6G71_RS06825	COG3676	manually curated
I6G71_RS06835	COG0004	ammonium transporteR
I6G71_RS06845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I6G71_RS06850	COG1177	transmembrane transport
I6G71_RS06855	COG1176	ABC-type spermidine putrescine transport system, permease component I
I6G71_RS06860	COG3842	ATPase activity
I6G71_RS06875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I6G71_RS06880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I6G71_RS06885	COG1862	Preprotein translocase
I6G71_RS06890	COG0123	including yeast histone deacetylase and acetoin utilization protein
I6G71_RS06895	COG1063	alcohol dehydrogenase
I6G71_RS06920	COG0805	protein transport
I6G71_RS06940	COG0745	RESPONSE REGULATOR receiver
I6G71_RS06945	COG2205	protein histidine kinase activity
I6G71_RS06980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6G71_RS06985	COG0803	Belongs to the bacterial solute-binding protein 9 family
I6G71_RS07060	COG3676	manually curated
I6G71_RS07075	COG0644	oxidoreductase
I6G71_RS07075	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
I6G71_RS07125	COG1522	sequence-specific DNA binding
I6G71_RS07135	COG2832	Protein of unknown function (DUF454)
I6G71_RS07175	COG1477	protein flavinylation
I6G71_RS07180	COG2991	Protein conserved in bacteria
I6G71_RS07190	COG1045	serine acetyltransferase
I6G71_RS07250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I6G71_RS07255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I6G71_RS07265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6G71_RS07275	COG1064	alcohol dehydrogenase
I6G71_RS07280	COG1196	nuclear chromosome segregation
I6G71_RS07295	COG1620	l-lactate permease
I6G71_RS07310	COG1448	Aminotransferase
I6G71_RS07330	COG1757	Na H antiporter
I6G71_RS07345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I6G71_RS07350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I6G71_RS07355	COG1757	Na H antiporter
I6G71_RS07375	COG3759	membrane
I6G71_RS07380	COG0720	synthase
I6G71_RS07430	COG3210	domain, Protein
I6G71_RS07460	COG3210	domain, Protein
I6G71_RS07465	COG2831	hemolysin activation secretion protein
I6G71_RS07510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
I6G71_RS07525	COG1530	ribonuclease E activity
I6G71_RS07545	COG2851	Citrate transporter
I6G71_RS07550	COG0431	NADPH-dependent FMN reductase
I6G71_RS07580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6G71_RS07585	COG1333	cytochrome c biogenesis protein
I6G71_RS07640	COG0121	glutamine amidotransferase
I6G71_RS07650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I6G71_RS07650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I6G71_RS07670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
I6G71_RS07675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I6G71_RS07685	COG3977	Valine--pyruvate aminotransferase
I6G71_RS07690	COG0613	PHP domain protein
I6G71_RS07765	COG0196	riboflavin kinase activity
I6G71_RS07785	COG0012	GTP binding
I6G71_RS07815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I6G71_RS07825	COG0489	protein tyrosine kinase activity
I6G71_RS07845	COG2852	Protein conserved in bacteria
I6G71_RS07865	COG0583	DNA-binding transcription factor activity
I6G71_RS07870	COG2249	NAD(P)H dehydrogenase (quinone) activity
I6G71_RS07885	COG0511	ligase activity, forming carbon-carbon bonds
I6G71_RS07890	COG0439	Biotin carboxylase
I6G71_RS07955	COG1214	PFAM Peptidase M22, glycoprotease
I6G71_RS07985	COG1505	serine-type exopeptidase activity
I6G71_RS08010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I6G71_RS08015	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
I6G71_RS08020	COG1956	GAF domain-containing protein
I6G71_RS08090	COG3676	manually curated
I6G71_RS08130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
I6G71_RS08185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I6G71_RS08200	COG1028	Short-chain dehydrogenase reductase Sdr
I6G71_RS08210	COG1943	Transposase
I6G71_RS08230	COG0483	inositol monophosphate 1-phosphatase activity
I6G71_RS08235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I6G71_RS08300	COG0356	it plays a direct role in the translocation of protons across the membrane
I6G71_RS08330	COG1464	Belongs to the NlpA lipoprotein family
I6G71_RS08335	COG2011	ABC-type metal ion transport system permease component
I6G71_RS08340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I6G71_RS08360	COG1610	YqeY-like protein
I6G71_RS08370	COG2969	positive regulation of protein catabolic process
I6G71_RS08375	COG0625	glutathione transferase activity
I6G71_RS08410	COG0824	Thioesterase
I6G71_RS08430	COG2854	intermembrane phospholipid transfer
I6G71_RS08435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
I6G71_RS08440	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
I6G71_RS08445	COG1127	ABC transporter
I6G71_RS08470	COG1012	belongs to the aldehyde dehydrogenase family
I6G71_RS08485	COG0512	Glutamine amidotransferase of anthranilate synthase
I6G71_RS08485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I6G71_RS08520	COG3676	manually curated
I6G71_RS08525	COG0733	neurotransmitter:sodium symporter activity
I6G71_RS08565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I6G71_RS08565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I6G71_RS08635	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6G71_RS08640	COG4605	iron ion homeostasis
I6G71_RS08650	COG4604	ABC transporter, ATP-binding protein
I6G71_RS08655	COG0347	Belongs to the P(II) protein family
I6G71_RS08675	COG2239	Acts as a magnesium transporter
I6G71_RS08685	COG0791	NLP P60 protein
I6G71_RS08695	COG1380	Effector of murein hydrolase LrgA
I6G71_RS08700	COG1346	cytolysis
I6G71_RS08710	COG0038	chloride channel
I6G71_RS08715	COG1643	Atp-dependent helicase
I6G71_RS08735	COG1643	Atp-dependent helicase
I6G71_RS08770	COG1555	photosystem II stabilization
I6G71_RS08770	COG1596	polysaccharide export
I6G71_RS08800	COG0564	pseudouridine synthase activity
I6G71_RS08825	COG0799	negative regulation of ribosome biogenesis
I6G71_RS08835	COG0288	reversible hydration of carbon dioxide
I6G71_RS08845	COG2610	gluconate transmembrane transporter activity
I6G71_RS08850	COG3265	gluconokinase activity
I6G71_RS08865	COG0814	amino acid
I6G71_RS08875	COG1368	sulfuric ester hydrolase activity
I6G71_RS08940	COG3842	ATPase activity
I6G71_RS08950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I6G71_RS08965	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
I6G71_RS08970	COG1793	dna ligase
I6G71_RS08975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I6G71_RS08985	COG2857	Cytochrome c1
I6G71_RS08990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
I6G71_RS08995	COG0723	plastoquinol--plastocyanin reductase activity
I6G71_RS09005	COG0583	DNA-binding transcription factor activity
I6G71_RS09045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I6G71_RS09055	COG2056	Na+-H+ antiporter family
I6G71_RS09070	COG0312	modulator of DNA gyrase
I6G71_RS09115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
I6G71_RS09160	COG0708	Exodeoxyribonuclease III
I6G71_RS09190	COG3038	cytochrome b561
I6G71_RS09220	COG0024	Methionine aminopeptidase
I6G71_RS09355	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
I6G71_RS09355	COG0616	signal peptide processing
I6G71_RS09360	COG1546	Belongs to the CinA family
I6G71_RS09360	COG1058	Belongs to the CinA family
I6G71_RS09395	COG0729	surface antigen
I6G71_RS09425	COG1546	Belongs to the CinA family
I6G71_RS09455	COG2824	Alkylphosphonate utilization operon protein PhnA
I6G71_RS09495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I6G71_RS09535	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
I6G71_RS09540	COG1519	Transferase
I6G71_RS09550	COG0861	Integral membrane protein TerC family
I6G71_RS09580	COG2884	Cell division ATP-binding protein ftsE
I6G71_RS09585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I6G71_RS09630	COG1335	isochorismatase
I6G71_RS09635	COG0859	PFAM glycosyl transferase family 9
I6G71_RS09650	COG1739	Uncharacterized protein family UPF0029
I6G71_RS09685	COG1595	DNA-templated transcription, initiation
I6G71_RS09690	COG3219	Protein conserved in bacteria
I6G71_RS09705	COG2259	Doxx family
I6G71_RS09710	COG4667	esterase of the alpha-beta hydrolase superfamily
I6G71_RS09725	COG3104	oligopeptide transport
I6G71_RS09735	COG1289	transmembrane transporter activity
I6G71_RS09760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I6G71_RS09795	COG1555	photosystem II stabilization
I6G71_RS09795	COG1596	polysaccharide export
I6G71_RS09805	COG1297	OPT oligopeptide transporter protein
I6G71_RS09920	COG0786	glutamate:sodium symporter activity
I6G71_RS09955	COG0469	pyruvate kinase activity
I6G71_RS10010	COG1652	LysM domain
I6G71_RS10035	COG5000	phosphorelay sensor kinase activity
I6G71_RS10040	COG2204	response regulator
I6G71_RS10045	COG0758	DNA mediated transformation
I6G71_RS10075	COG0742	ribosomal rna small subunit methyltransferase
I6G71_RS10080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6G71_RS10295	COG0201	protein transport
I6G71_RS10380	COG1115	amino acid carrier protein
I6G71_RS10465	COG1192	Involved in chromosome partitioning
I6G71_RS10485	COG1115	amino acid carrier protein
I6G71_RS10495	COG1530	ribonuclease E activity
I6G71_RS10545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I6G71_RS10590	COG1760	l-serine dehydratase
I6G71_RS10605	COG0339	signal peptide processing
I6G71_RS10615	COG1943	Transposase
I6G71_RS10625	COG0753	catalase activity
I6G71_RS10630	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
I6G71_RS10650	COG0385	Bile acid
I6G71_RS10655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I6G71_RS10705	COG1914	H( )-stimulated, divalent metal cation uptake system
I6G71_RS10715	COG1984	allophanate hydrolase subunit 2
I6G71_RS10720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
I6G71_RS10725	COG0210	DNA helicase
I6G71_RS10745	COG3676	manually curated
I6G71_RS10755	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
I6G71_RS10765	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
I6G71_RS10785	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
I6G71_RS10790	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
I6G71_RS10875	COG0142	geranyltranstransferase activity
I6G71_RS10895	COG1132	(ABC) transporter
I6G71_RS10920	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I6G71_RS10925	COG1040	competence protein
I6G71_RS10940	COG0514	ATP-dependent DNA helicase (RecQ)
I6G71_RS10965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I6G71_RS10980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I6G71_RS10985	COG0557	exoribonuclease II activity
I6G71_RS10990	COG1611	Belongs to the LOG family
I6G71_RS11000	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
I6G71_RS11010	COG1199	ATP-dependent helicase activity
I6G71_RS11020	COG0415	Belongs to the DNA photolyase family
I6G71_RS11025	COG0583	DNA-binding transcription factor activity
I6G71_RS11030	COG2259	Doxx family
I6G71_RS11050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I6G71_RS11055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY