locus-tag	class	description
A6L27_RS00040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6L27_RS00055	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A6L27_RS00065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6L27_RS00085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6L27_RS00085	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A6L27_RS00100	COG0497	DNA recombination
A6L27_RS00105	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A6L27_RS00110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A6L27_RS00145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6L27_RS00145	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A6L27_RS00255	COG2354	Protein conserved in bacteria
A6L27_RS00270	COG1561	YicC-like family, N-terminal region
A6L27_RS00285	COG1466	dna polymerase III delta subunit
A6L27_RS00290	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
A6L27_RS00300	COG0385	Bile acid
A6L27_RS00345	COG1126	abc transporter atp-binding protein
A6L27_RS00360	COG0285	dihydrofolate synthase activity
A6L27_RS00375	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A6L27_RS00440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A6L27_RS00490	COG0281	malic enzyme
A6L27_RS00490	COG0280	phosphate acetyltransferase
A6L27_RS00500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A6L27_RS00520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6L27_RS00645	COG2732	(Barnase) inhibitor
A6L27_RS00665	COG0494	nUDIX hydrolase
A6L27_RS00685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A6L27_RS00705	COG1178	ABC-type Fe3 transport system permease component
A6L27_RS00750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A6L27_RS00760	COG0463	Glycosyl transferase, family 2
A6L27_RS00780	COG2833	Protein of unknown function (DUF455)
A6L27_RS00810	COG0004	ammonium transporteR
A6L27_RS00815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6L27_RS00820	COG1177	transmembrane transport
A6L27_RS00825	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6L27_RS00830	COG3842	ATPase activity
A6L27_RS00840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A6L27_RS00845	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A6L27_RS00850	COG1862	Preprotein translocase
A6L27_RS00855	COG0123	including yeast histone deacetylase and acetoin utilization protein
A6L27_RS00860	COG1063	alcohol dehydrogenase
A6L27_RS00885	COG0805	protein transport
A6L27_RS00905	COG0745	RESPONSE REGULATOR receiver
A6L27_RS00910	COG2205	protein histidine kinase activity
A6L27_RS00945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6L27_RS00950	COG0803	Belongs to the bacterial solute-binding protein 9 family
A6L27_RS00980	COG3676	manually curated
A6L27_RS00990	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A6L27_RS00990	COG0644	oxidoreductase
A6L27_RS01030	COG1522	sequence-specific DNA binding
A6L27_RS01040	COG2832	Protein of unknown function (DUF454)
A6L27_RS01080	COG1477	protein flavinylation
A6L27_RS01085	COG2991	Protein conserved in bacteria
A6L27_RS01095	COG1045	serine acetyltransferase
A6L27_RS01140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A6L27_RS01145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A6L27_RS01155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6L27_RS01165	COG1064	alcohol dehydrogenase
A6L27_RS01170	COG1196	nuclear chromosome segregation
A6L27_RS01185	COG1620	l-lactate permease
A6L27_RS01200	COG1448	Aminotransferase
A6L27_RS01220	COG1757	Na H antiporter
A6L27_RS01245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A6L27_RS01250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A6L27_RS01255	COG1757	Na H antiporter
A6L27_RS01275	COG3759	membrane
A6L27_RS01280	COG0720	synthase
A6L27_RS01400	COG2831	hemolysin activation secretion protein
A6L27_RS01460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A6L27_RS01475	COG1530	ribonuclease E activity
A6L27_RS01485	COG0745	RESPONSE REGULATOR receiver
A6L27_RS01490	COG2851	Citrate transporter
A6L27_RS01500	COG0431	NADPH-dependent FMN reductase
A6L27_RS01530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A6L27_RS01535	COG1333	cytochrome c biogenesis protein
A6L27_RS01595	COG0121	glutamine amidotransferase
A6L27_RS01605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6L27_RS01605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6L27_RS01625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A6L27_RS01645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A6L27_RS01655	COG3977	Valine--pyruvate aminotransferase
A6L27_RS01660	COG0613	PHP domain protein
A6L27_RS01715	COG0196	riboflavin kinase activity
A6L27_RS01740	COG0012	GTP binding
A6L27_RS01775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6L27_RS01785	COG0489	protein tyrosine kinase activity
A6L27_RS01820	COG2852	Protein conserved in bacteria
A6L27_RS01845	COG0583	DNA-binding transcription factor activity
A6L27_RS01850	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6L27_RS01870	COG0511	ligase activity, forming carbon-carbon bonds
A6L27_RS01875	COG0439	Biotin carboxylase
A6L27_RS01925	COG1214	PFAM Peptidase M22, glycoprotease
A6L27_RS01955	COG1505	serine-type exopeptidase activity
A6L27_RS01985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6L27_RS01990	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A6L27_RS01995	COG1956	GAF domain-containing protein
A6L27_RS02040	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A6L27_RS02155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A6L27_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
A6L27_RS02180	COG1943	Transposase
A6L27_RS02230	COG1199	ATP-dependent helicase activity
A6L27_RS02240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A6L27_RS02250	COG1611	Belongs to the LOG family
A6L27_RS02255	COG0557	exoribonuclease II activity
A6L27_RS02260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6L27_RS02275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A6L27_RS02295	COG0514	ATP-dependent DNA helicase (RecQ)
A6L27_RS02315	COG2226	methyltransferase
A6L27_RS02325	COG1040	competence protein
A6L27_RS02330	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A6L27_RS02355	COG1132	(ABC) transporter
A6L27_RS02370	COG0142	geranyltranstransferase activity
A6L27_RS02435	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A6L27_RS02440	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
A6L27_RS02460	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6L27_RS02475	COG3676	manually curated
A6L27_RS02500	COG0210	DNA helicase
A6L27_RS02510	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A6L27_RS02515	COG1984	allophanate hydrolase subunit 2
A6L27_RS02525	COG1914	H( )-stimulated, divalent metal cation uptake system
A6L27_RS02580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6L27_RS02585	COG0385	Bile acid
A6L27_RS02600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A6L27_RS02600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A6L27_RS02605	COG0753	catalase activity
A6L27_RS02620	COG1943	Transposase
A6L27_RS02630	COG0339	signal peptide processing
A6L27_RS02645	COG1760	l-serine dehydratase
A6L27_RS02650	COG1760	l-serine dehydratase
A6L27_RS02695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A6L27_RS02740	COG0564	pseudouridine synthase activity
A6L27_RS02750	COG1530	ribonuclease E activity
A6L27_RS02760	COG1115	amino acid carrier protein
A6L27_RS02775	COG1192	Involved in chromosome partitioning
A6L27_RS02855	COG1115	amino acid carrier protein
A6L27_RS02935	COG0201	protein transport
A6L27_RS03110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A6L27_RS03140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A6L27_RS03145	COG0742	ribosomal rna small subunit methyltransferase
A6L27_RS03150	COG1476	TRANSCRIPTIONal
A6L27_RS03175	COG0758	DNA mediated transformation
A6L27_RS03180	COG2204	response regulator
A6L27_RS03185	COG5000	phosphorelay sensor kinase activity
A6L27_RS03215	COG1652	LysM domain
A6L27_RS03330	COG0469	pyruvate kinase activity
A6L27_RS03360	COG0786	glutamate:sodium symporter activity
A6L27_RS03400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A6L27_RS03420	COG2089	acid synthase
A6L27_RS03490	COG1297	OPT oligopeptide transporter protein
A6L27_RS03505	COG1555	photosystem II stabilization
A6L27_RS03505	COG1596	polysaccharide export
A6L27_RS03545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A6L27_RS03570	COG1289	transmembrane transporter activity
A6L27_RS03590	COG1546	Belongs to the CinA family
A6L27_RS03615	COG2824	Alkylphosphonate utilization operon protein PhnA
A6L27_RS03660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6L27_RS03700	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A6L27_RS03705	COG1519	Transferase
A6L27_RS03715	COG0861	Integral membrane protein TerC family
A6L27_RS03745	COG2884	Cell division ATP-binding protein ftsE
A6L27_RS03750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6L27_RS03795	COG1335	isochorismatase
A6L27_RS03800	COG0859	PFAM glycosyl transferase family 9
A6L27_RS03815	COG1739	Uncharacterized protein family UPF0029
A6L27_RS03835	COG3676	manually curated
A6L27_RS03865	COG1595	DNA-templated transcription, initiation
A6L27_RS03870	COG3219	Protein conserved in bacteria
A6L27_RS03885	COG2259	Doxx family
A6L27_RS03890	COG4667	esterase of the alpha-beta hydrolase superfamily
A6L27_RS03910	COG3104	oligopeptide transport
A6L27_RS03920	COG0729	surface antigen
A6L27_RS03950	COG1058	Belongs to the CinA family
A6L27_RS03950	COG1546	Belongs to the CinA family
A6L27_RS03955	COG0616	signal peptide processing
A6L27_RS04105	COG0024	Methionine aminopeptidase
A6L27_RS04135	COG3038	cytochrome b561
A6L27_RS04155	COG0708	Exodeoxyribonuclease III
A6L27_RS04200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A6L27_RS04250	COG0312	modulator of DNA gyrase
A6L27_RS04260	COG2056	Na+-H+ antiporter family
A6L27_RS04275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A6L27_RS04315	COG0583	DNA-binding transcription factor activity
A6L27_RS04325	COG0723	plastoquinol--plastocyanin reductase activity
A6L27_RS04330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A6L27_RS04335	COG2857	Cytochrome c1
A6L27_RS04345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6L27_RS04350	COG1793	dna ligase
A6L27_RS04355	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A6L27_RS04370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A6L27_RS04375	COG3842	ATPase activity
A6L27_RS04460	COG1368	sulfuric ester hydrolase activity
A6L27_RS04470	COG0814	amino acid
A6L27_RS04485	COG3265	gluconokinase activity
A6L27_RS04490	COG2610	gluconate transmembrane transporter activity
A6L27_RS04500	COG0288	reversible hydration of carbon dioxide
A6L27_RS04510	COG0799	negative regulation of ribosome biogenesis
A6L27_RS04535	COG0564	pseudouridine synthase activity
A6L27_RS04570	COG1596	polysaccharide export
A6L27_RS04570	COG1555	photosystem II stabilization
A6L27_RS04615	COG1643	Atp-dependent helicase
A6L27_RS04630	COG1643	Atp-dependent helicase
A6L27_RS04635	COG0038	chloride channel
A6L27_RS04645	COG1346	cytolysis
A6L27_RS04660	COG0791	NLP P60 protein
A6L27_RS04670	COG2239	Acts as a magnesium transporter
A6L27_RS04695	COG0347	Belongs to the P(II) protein family
A6L27_RS04705	COG4604	ABC transporter, ATP-binding protein
A6L27_RS04715	COG4605	iron ion homeostasis
A6L27_RS04720	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6L27_RS04770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6L27_RS04770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6L27_RS04780	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
A6L27_RS04800	COG0733	neurotransmitter:sodium symporter activity
A6L27_RS04805	COG3676	manually curated
A6L27_RS04840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A6L27_RS04840	COG0512	Glutamine amidotransferase of anthranilate synthase
A6L27_RS04850	COG1012	belongs to the aldehyde dehydrogenase family
A6L27_RS04865	COG1127	ABC transporter
A6L27_RS04870	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A6L27_RS04875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A6L27_RS04880	COG2854	intermembrane phospholipid transfer
A6L27_RS04900	COG0824	Thioesterase
A6L27_RS04935	COG0625	glutathione transferase activity
A6L27_RS04940	COG2969	positive regulation of protein catabolic process
A6L27_RS04950	COG1610	YqeY-like protein
A6L27_RS04970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A6L27_RS04975	COG2011	ABC-type metal ion transport system permease component
A6L27_RS04980	COG1464	Belongs to the NlpA lipoprotein family
A6L27_RS05015	COG0356	it plays a direct role in the translocation of protons across the membrane
A6L27_RS05070	COG1216	Glycosyl transferase, family 2
A6L27_RS05090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A6L27_RS05115	COG0583	DNA-binding transcription factor activity
A6L27_RS05120	COG2259	Doxx family
A6L27_RS05140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A6L27_RS05145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6L27_RS05190	COG1596	polysaccharide export
A6L27_RS05190	COG1555	photosystem II stabilization
A6L27_RS05205	COG3676	manually curated
A6L27_RS05220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A6L27_RS05230	COG2954	triphosphatase activity
A6L27_RS05235	COG1981	membrane
A6L27_RS05265	COG0739	heme binding
A6L27_RS05270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A6L27_RS05320	COG0142	geranyltranstransferase activity
A6L27_RS05380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6L27_RS05395	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A6L27_RS05420	COG2350	Protein conserved in bacteria
A6L27_RS05445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6L27_RS05470	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A6L27_RS05480	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A6L27_RS05485	COG1137	ATPase activity
A6L27_RS05515	COG2814	Major facilitator Superfamily
A6L27_RS05605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6L27_RS05610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6L27_RS05615	COG0583	DNA-binding transcription factor activity
A6L27_RS05635	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A6L27_RS05640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A6L27_RS05645	COG0488	(ABC) transporter
A6L27_RS05655	COG2017	converts alpha-aldose to the beta-anomer
A6L27_RS05665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A6L27_RS05715	COG0640	Transcriptional regulator
A6L27_RS05720	COG0708	Exodeoxyribonuclease III
A6L27_RS05750	COG2960	long-chain fatty acid transporting porin activity
A6L27_RS05820	COG2194	sulfuric ester hydrolase activity
A6L27_RS05825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A6L27_RS05885	COG2252	PERMEase
A6L27_RS05900	COG0372	Belongs to the citrate synthase family
A6L27_RS05910	COG5505	Protein of unknown function (DUF819)
A6L27_RS05920	COG2828	Protein conserved in bacteria
A6L27_RS05930	COG0009	L-threonylcarbamoyladenylate synthase
A6L27_RS05935	COG1959	2 iron, 2 sulfur cluster binding
A6L27_RS05950	COG0287	Prephenate dehydrogenase
A6L27_RS05955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A6L27_RS06025	COG0697	spore germination
A6L27_RS06030	COG2814	Major facilitator Superfamily
A6L27_RS06090	COG0802	atpase or kinase
A6L27_RS06155	COG0471	metal ion transport
A6L27_RS06160	COG1376	ErfK ybiS ycfS ynhG family protein
A6L27_RS06165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A6L27_RS06175	COG2830	Protein of unknown function (DUF452)
A6L27_RS06180	COG0500	methyltransferase
A6L27_RS06260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6L27_RS06265	COG1538	Outer membrane efflux protein
A6L27_RS06275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A6L27_RS06280	COG2999	glutathione oxidoreductase activity
A6L27_RS06295	COG1994	Peptidase M50
A6L27_RS06315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6L27_RS06315	COG3453	Protein conserved in bacteria
A6L27_RS06325	COG3278	Belongs to the heme-copper respiratory oxidase family
A6L27_RS06340	COG2010	Cytochrome c
A6L27_RS06350	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A6L27_RS06355	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A6L27_RS06390	COG1620	l-lactate permease
A6L27_RS06410	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A6L27_RS06430	COG0733	neurotransmitter:sodium symporter activity
A6L27_RS06460	COG3676	manually curated
A6L27_RS06500	COG0586	Pfam SNARE associated Golgi protein
A6L27_RS06505	COG0252	asparaginase activity
A6L27_RS06520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6L27_RS06565	COG3245	cytochrome
A6L27_RS06605	COG3008	intermembrane lipid transfer
A6L27_RS06605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A6L27_RS06610	COG2995	paraquat-inducible protein a
A6L27_RS06640	COG0826	peptidase U32
A6L27_RS06650	COG0561	phosphatase activity
A6L27_RS06670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A6L27_RS06675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A6L27_RS06710	COG1555	photosystem II stabilization
A6L27_RS06710	COG1596	polysaccharide export
A6L27_RS06770	COG1115	amino acid carrier protein
A6L27_RS06775	COG1272	protein, Hemolysin III
A6L27_RS06785	COG1160	GTP binding
A6L27_RS06815	COG2194	sulfuric ester hydrolase activity
A6L27_RS06820	COG0778	Nitroreductase
A6L27_RS06835	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A6L27_RS06865	COG1619	proteins homologs of microcin C7 resistance protein MccF
A6L27_RS06905	COG0351	phosphomethylpyrimidine kinase
A6L27_RS06925	COG0569	domain protein
A6L27_RS06980	COG5002	protein histidine kinase activity
A6L27_RS06995	COG1275	C4-dicarboxylate transporter malic acid transport protein
A6L27_RS07005	COG3547	Transposase (IS116 IS110 IS902 family)
A6L27_RS07055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A6L27_RS07065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A6L27_RS07100	COG0616	signal peptide processing
A6L27_RS07125	COG2084	Dehydrogenase
A6L27_RS07155	COG1999	signal sequence binding
A6L27_RS07165	COG0028	Belongs to the TPP enzyme family
A6L27_RS07190	COG1049	propionate catabolic process, 2-methylcitrate cycle
A6L27_RS07220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A6L27_RS07230	COG1765	OsmC-like protein
A6L27_RS07235	COG1802	Transcriptional regulator
A6L27_RS07240	COG2431	L-lysine efflux transmembrane transporter activity
A6L27_RS07245	COG1349	DNA-binding transcription factor activity
A6L27_RS07275	COG0318	PFAM AMP-dependent synthetase and ligase
A6L27_RS07350	COG3945	hemerythrin HHE cation binding domain
A6L27_RS07365	COG1881	PFAM PEBP family protein
A6L27_RS07370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A6L27_RS07380	COG0859	PFAM glycosyl transferase family 9
A6L27_RS07395	COG0277	FAD linked oxidase domain protein
A6L27_RS07415	COG1562	ergosterol biosynthetic process
A6L27_RS07480	COG0765	amino acid transport
A6L27_RS07515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A6L27_RS07560	COG1966	Carbon starvation protein
A6L27_RS07590	COG1253	flavin adenine dinucleotide binding
A6L27_RS07605	COG1607	acyl-coa hydrolase
A6L27_RS07645	COG1942	4-Oxalocrotonate Tautomerase
A6L27_RS07650	COG0436	Aminotransferase
A6L27_RS07695	COG1943	Transposase
A6L27_RS07715	COG0741	lytic transglycosylase activity
A6L27_RS07715	COG0739	heme binding
A6L27_RS07715	COG1196	nuclear chromosome segregation
A6L27_RS07720	COG2814	Major facilitator Superfamily
A6L27_RS07730	COG0697	spore germination
A6L27_RS07740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A6L27_RS07755	COG0348	domain, Protein
A6L27_RS07765	COG2070	2-Nitropropane dioxygenase
A6L27_RS07805	COG0210	DNA helicase
A6L27_RS07850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A6L27_RS07875	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A6L27_RS07880	COG1139	Iron-sulfur cluster binding protein
A6L27_RS07890	COG0247	lactate metabolic process
A6L27_RS07895	COG0477	Major facilitator Superfamily
A6L27_RS07900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6L27_RS07905	COG0791	NLP P60 protein
A6L27_RS07975	COG0513	Belongs to the DEAD box helicase family
A6L27_RS07985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6L27_RS08000	COG1560	Kdo2-lipid A biosynthetic process
A6L27_RS08015	COG0308	aminopeptidase N
A6L27_RS08040	COG3676	manually curated
A6L27_RS08065	COG1194	a g-specific adenine glycosylase
A6L27_RS08075	COG0800	Aldolase
A6L27_RS08085	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A6L27_RS08100	COG1737	Transcriptional regulator
A6L27_RS08145	COG3036	rescue of stalled ribosome
A6L27_RS08155	COG0822	iron-sulfur transferase activity
A6L27_RS08175	COG1304	FMN binding
A6L27_RS08180	COG3421	Type III restriction
A6L27_RS08185	COG2189	Belongs to the N(4) N(6)-methyltransferase family
A6L27_RS08190	COG2189	Belongs to the N(4) N(6)-methyltransferase family
A6L27_RS08235	COG0513	Belongs to the DEAD box helicase family
A6L27_RS08260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A6L27_RS08285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A6L27_RS08285	COG0543	2 iron, 2 sulfur cluster binding
A6L27_RS08295	COG2990	Protein conserved in bacteria
A6L27_RS08310	COG2095	MarC family integral membrane protein
A6L27_RS08315	COG1012	belongs to the aldehyde dehydrogenase family
A6L27_RS08325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A6L27_RS08325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A6L27_RS08335	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A6L27_RS08355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6L27_RS08360	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6L27_RS08365	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A6L27_RS08380	COG0179	Fumarylacetoacetate (FAA) hydrolase
A6L27_RS08395	COG3045	CreA protein
A6L27_RS08405	COG0793	Belongs to the peptidase S41A family
A6L27_RS08435	COG2217	Heavy metal translocating P-type atpase
A6L27_RS08440	COG0492	ferredoxin-NADP+ reductase activity
A6L27_RS08465	COG0730	response to heat
A6L27_RS08470	COG1183	phosphatidylcholine synthase activity
A6L27_RS08530	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A6L27_RS08535	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A6L27_RS08540	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A6L27_RS08545	COG0789	Transcriptional regulator
A6L27_RS08575	COG1388	LysM domain
A6L27_RS08575	COG0741	lytic transglycosylase activity
A6L27_RS08600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6L27_RS08610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6L27_RS08615	COG0633	Ferredoxin
A6L27_RS08645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A6L27_RS08655	COG2951	lytic endotransglycosylase activity
A6L27_RS08665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A6L27_RS08670	COG0318	PFAM AMP-dependent synthetase and ligase
A6L27_RS08700	COG2608	mercury ion transmembrane transporter activity
A6L27_RS08705	COG4797	methyltransferase
A6L27_RS08705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A6L27_RS08720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A6L27_RS08730	COG0523	cobalamin synthesis protein
A6L27_RS08735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A6L27_RS08760	COG0251	oxidation-reduction process
A6L27_RS08775	COG0697	spore germination
A6L27_RS08780	COG1027	Aspartate ammonia-lyase
A6L27_RS08785	COG2353	YceI-like domain
A6L27_RS08835	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A6L27_RS08845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A6L27_RS08850	COG2217	Heavy metal translocating P-type atpase
A6L27_RS08885	COG0583	DNA-binding transcription factor activity
A6L27_RS08900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A6L27_RS08925	COG1216	Glycosyl transferase, family 2
A6L27_RS08955	COG2197	response regulator
A6L27_RS08960	COG3850	Histidine kinase
A6L27_RS08970	COG0307	riboflavin synthase, alpha
A6L27_RS08990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A6L27_RS09010	COG0488	(ABC) transporter
A6L27_RS09015	COG1393	Belongs to the ArsC family
A6L27_RS09050	COG2890	protein-(glutamine-N5) methyltransferase activity
A6L27_RS09055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A6L27_RS09080	COG0488	(ABC) transporter
A6L27_RS09125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A6L27_RS09140	COG0330	HflC and HflK could
A6L27_RS09145	COG0628	permease
A6L27_RS09205	COG0557	exoribonuclease II activity
A6L27_RS09230	COG1217	gtp-binding protein TYPA
A6L27_RS09265	COG2895	sulfate adenylyltransferase (ATP) activity
A6L27_RS09305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A6L27_RS09325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6L27_RS09340	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A6L27_RS09345	COG2975	iron-sulfur cluster assembly
A6L27_RS09360	COG0633	Ferredoxin
A6L27_RS09380	COG1562	ergosterol biosynthetic process
A6L27_RS09390	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A6L27_RS09425	COG4178	(ABC) transporter
A6L27_RS09430	COG3392	D12 class N6 adenine-specific DNA methyltransferase
A6L27_RS09450	COG3093	addiction module antidote protein HigA
A6L27_RS09510	COG4178	(ABC) transporter
A6L27_RS09515	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A6L27_RS09540	COG2866	Carboxypeptidase
A6L27_RS09550	COG3012	SEC-C Motif Domain Protein
A6L27_RS09550	COG3318	Belongs to the UPF0149 family
A6L27_RS09595	COG0494	nUDIX hydrolase
A6L27_RS09610	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A6L27_RS09620	COG2841	Protein conserved in bacteria
A6L27_RS09625	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A6L27_RS09630	COG0405	Gamma-glutamyltransferase
A6L27_RS09645	COG0586	Pfam SNARE associated Golgi protein
A6L27_RS09650	COG0488	(ABC) transporter
A6L27_RS09670	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A6L27_RS09680	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A6L27_RS09710	COG2801	Transposase and inactivated derivatives
A6L27_RS09820	COG0277	FAD linked oxidase domain protein
A6L27_RS09845	COG1773	rubredoxin
A6L27_RS09950	COG0560	Phosphoserine phosphatase
A6L27_RS09955	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A6L27_RS09965	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A6L27_RS09970	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6L27_RS10010	COG3676	manually curated
A6L27_RS10025	COG0512	Glutamine amidotransferase of anthranilate synthase
A6L27_RS10060	COG1943	Transposase
A6L27_RS10080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6L27_RS10085	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6L27_RS10090	COG0567	Dehydrogenase, E1 component
A6L27_RS10105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A6L27_RS10135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A6L27_RS10135	COG0678	peroxiredoxin activity
A6L27_RS10175	COG2813	Specifically methylates the guanine in position
A6L27_RS10175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A6L27_RS10225	COG2233	PERMEase
A6L27_RS10260	COG1607	acyl-coa hydrolase
A6L27_RS10265	COG4221	oxidoreductase activity
A6L27_RS10380	COG1196	nuclear chromosome segregation
A6L27_RS10530	COG0582	viral genome integration into host DNA
A6L27_RS10550	COG0436	Aminotransferase
A6L27_RS10590	COG0305	Participates in initiation and elongation during chromosome replication
A6L27_RS10595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A6L27_RS10600	COG1755	Isoprenylcysteine carboxyl methyltransferase
A6L27_RS10615	COG4208	sulfate ABC transporter
A6L27_RS10625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A6L27_RS10630	COG1686	Belongs to the peptidase S11 family
A6L27_RS10810	COG0438	transferase activity, transferring glycosyl groups
A6L27_RS10815	COG1702	phosphate starvation-inducible protein PhoH
A6L27_RS10845	COG0312	modulator of DNA gyrase
A6L27_RS10850	COG1278	Cold shock
A6L27_RS10880	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A6L27_RS10880	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A6L27_RS10925	COG1309	transcriptional regulator
A6L27_RS10930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6L27_RS10945	COG1187	pseudouridine synthase activity
A6L27_RS10950	COG0778	Nitroreductase
A6L27_RS10960	COG0626	cystathionine gamma-synthase activity
A6L27_RS10980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A6L27_RS10985	COG2867	negative regulation of translational initiation
A6L27_RS11010	COG0471	metal ion transport
A6L27_RS11015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A6L27_RS11025	COG1126	abc transporter atp-binding protein
A6L27_RS11030	COG0765	amino acid transport
A6L27_RS11035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6L27_RS11040	COG2837	iron assimilation
A6L27_RS11045	COG1074	ATP-dependent DNA helicase activity
A6L27_RS11105	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A6L27_RS11115	COG0084	hydrolase, TatD family'
A6L27_RS11135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A6L27_RS11145	COG0681	Belongs to the peptidase S26 family