locus-tag	class	description
DV160_RS00030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DV160_RS00035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DV160_RS00040	COG1956	GAF domain-containing protein
DV160_RS00095	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DV160_RS00225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DV160_RS00240	COG1028	Short-chain dehydrogenase reductase Sdr
DV160_RS00250	COG1943	Transposase
DV160_RS00315	COG1199	ATP-dependent helicase activity
DV160_RS00325	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DV160_RS00335	COG1611	Belongs to the LOG family
DV160_RS00345	COG0557	exoribonuclease II activity
DV160_RS00360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DV160_RS00375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DV160_RS00400	COG0514	ATP-dependent DNA helicase (RecQ)
DV160_RS00420	COG2226	methyltransferase
DV160_RS00430	COG1040	competence protein
DV160_RS00435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DV160_RS00465	COG1132	(ABC) transporter
DV160_RS00480	COG0142	geranyltranstransferase activity
DV160_RS00550	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DV160_RS00555	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DV160_RS00575	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DV160_RS00580	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DV160_RS00590	COG3676	manually curated
DV160_RS00620	COG0210	DNA helicase
DV160_RS00630	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DV160_RS00635	COG1984	allophanate hydrolase subunit 2
DV160_RS00645	COG1914	H( )-stimulated, divalent metal cation uptake system
DV160_RS00700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DV160_RS00720	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DV160_RS00720	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DV160_RS00725	COG0753	catalase activity
DV160_RS00765	COG1943	Transposase
DV160_RS00780	COG0339	signal peptide processing
DV160_RS00800	COG1760	l-serine dehydratase
DV160_RS00805	COG1760	l-serine dehydratase
DV160_RS00850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DV160_RS00900	COG0564	pseudouridine synthase activity
DV160_RS00910	COG1530	ribonuclease E activity
DV160_RS00990	COG1115	amino acid carrier protein
DV160_RS01020	COG1192	Involved in chromosome partitioning
DV160_RS01105	COG1115	amino acid carrier protein
DV160_RS01195	COG0201	protein transport
DV160_RS01385	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DV160_RS01415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DV160_RS01420	COG0742	ribosomal rna small subunit methyltransferase
DV160_RS01425	COG1476	TRANSCRIPTIONal
DV160_RS01450	COG0758	DNA mediated transformation
DV160_RS01450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DV160_RS01455	COG2204	response regulator
DV160_RS01460	COG5000	phosphorelay sensor kinase activity
DV160_RS01485	COG1652	LysM domain
DV160_RS01585	COG0469	pyruvate kinase activity
DV160_RS01615	COG0786	glutamate:sodium symporter activity
DV160_RS01695	COG2089	acid synthase
DV160_RS01745	COG1297	OPT oligopeptide transporter protein
DV160_RS01755	COG1555	photosystem II stabilization
DV160_RS01755	COG1596	polysaccharide export
DV160_RS01795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DV160_RS01825	COG1289	transmembrane transporter activity
DV160_RS01945	COG1546	Belongs to the CinA family
DV160_RS01975	COG2824	Alkylphosphonate utilization operon protein PhnA
DV160_RS02025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DV160_RS02090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DV160_RS02095	COG1519	Transferase
DV160_RS02105	COG0861	Integral membrane protein TerC family
DV160_RS02140	COG2884	Cell division ATP-binding protein ftsE
DV160_RS02150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DV160_RS02205	COG1335	isochorismatase
DV160_RS02210	COG0859	PFAM glycosyl transferase family 9
DV160_RS02225	COG1739	Uncharacterized protein family UPF0029
DV160_RS02245	COG3676	manually curated
DV160_RS02275	COG1595	DNA-templated transcription, initiation
DV160_RS02280	COG3219	Protein conserved in bacteria
DV160_RS02295	COG2259	Doxx family
DV160_RS02300	COG4667	esterase of the alpha-beta hydrolase superfamily
DV160_RS02320	COG3104	oligopeptide transport
DV160_RS02335	COG0729	surface antigen
DV160_RS02375	COG1058	Belongs to the CinA family
DV160_RS02375	COG1546	Belongs to the CinA family
DV160_RS02380	COG0616	signal peptide processing
DV160_RS02565	COG0024	Methionine aminopeptidase
DV160_RS02595	COG3038	cytochrome b561
DV160_RS02625	COG0708	Exodeoxyribonuclease III
DV160_RS02675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DV160_RS02735	COG0312	modulator of DNA gyrase
DV160_RS02745	COG2056	Na+-H+ antiporter family
DV160_RS02760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DV160_RS02800	COG0583	DNA-binding transcription factor activity
DV160_RS02810	COG0723	plastoquinol--plastocyanin reductase activity
DV160_RS02815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DV160_RS02820	COG2857	Cytochrome c1
DV160_RS02830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DV160_RS02835	COG1793	dna ligase
DV160_RS02840	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DV160_RS02855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DV160_RS02885	COG3842	ATPase activity
DV160_RS03005	COG1368	sulfuric ester hydrolase activity
DV160_RS03015	COG0814	amino acid
DV160_RS03030	COG3265	gluconokinase activity
DV160_RS03035	COG2610	gluconate transmembrane transporter activity
DV160_RS03045	COG0288	reversible hydration of carbon dioxide
DV160_RS03055	COG0799	negative regulation of ribosome biogenesis
DV160_RS03080	COG0564	pseudouridine synthase activity
DV160_RS03115	COG1555	photosystem II stabilization
DV160_RS03115	COG1596	polysaccharide export
DV160_RS03165	COG1643	Atp-dependent helicase
DV160_RS03180	COG1643	Atp-dependent helicase
DV160_RS03185	COG0038	chloride channel
DV160_RS03195	COG1346	cytolysis
DV160_RS03215	COG0791	NLP P60 protein
DV160_RS03230	COG2239	Acts as a magnesium transporter
DV160_RS03255	COG0347	Belongs to the P(II) protein family
DV160_RS03265	COG4604	ABC transporter, ATP-binding protein
DV160_RS03275	COG4605	iron ion homeostasis
DV160_RS03280	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DV160_RS03345	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DV160_RS03345	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DV160_RS03355	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
DV160_RS03380	COG0733	neurotransmitter:sodium symporter activity
DV160_RS03385	COG3676	manually curated
DV160_RS03430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DV160_RS03430	COG0512	Glutamine amidotransferase of anthranilate synthase
DV160_RS03455	COG1012	belongs to the aldehyde dehydrogenase family
DV160_RS03480	COG1127	ABC transporter
DV160_RS03485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DV160_RS03490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DV160_RS03495	COG2854	intermembrane phospholipid transfer
DV160_RS03515	COG0824	Thioesterase
DV160_RS03545	COG0625	glutathione transferase activity
DV160_RS03550	COG2969	positive regulation of protein catabolic process
DV160_RS03560	COG1610	YqeY-like protein
DV160_RS03575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DV160_RS03580	COG2011	ABC-type metal ion transport system permease component
DV160_RS03585	COG1464	Belongs to the NlpA lipoprotein family
DV160_RS03625	COG0356	it plays a direct role in the translocation of protons across the membrane
DV160_RS03690	COG1216	Glycosyl transferase, family 2
DV160_RS03725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DV160_RS03730	COG0483	inositol monophosphate 1-phosphatase activity
DV160_RS03750	COG0415	Belongs to the DNA photolyase family
DV160_RS03755	COG0583	DNA-binding transcription factor activity
DV160_RS03760	COG2259	Doxx family
DV160_RS03780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DV160_RS03785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DV160_RS03830	COG1555	photosystem II stabilization
DV160_RS03830	COG1596	polysaccharide export
DV160_RS03860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DV160_RS03870	COG2954	triphosphatase activity
DV160_RS03875	COG1981	membrane
DV160_RS03915	COG0739	heme binding
DV160_RS03925	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DV160_RS03985	COG0142	geranyltranstransferase activity
DV160_RS04060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DV160_RS04075	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DV160_RS04100	COG2350	Protein conserved in bacteria
DV160_RS04125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DV160_RS04150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DV160_RS04160	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DV160_RS04165	COG1137	ATPase activity
DV160_RS04205	COG2814	Major facilitator Superfamily
DV160_RS04310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DV160_RS04315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DV160_RS04320	COG0583	DNA-binding transcription factor activity
DV160_RS04345	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DV160_RS04350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DV160_RS04355	COG0488	(ABC) transporter
DV160_RS04370	COG2017	converts alpha-aldose to the beta-anomer
DV160_RS04385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DV160_RS04435	COG0708	Exodeoxyribonuclease III
DV160_RS04480	COG2960	long-chain fatty acid transporting porin activity
DV160_RS04545	COG2194	sulfuric ester hydrolase activity
DV160_RS04550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DV160_RS04625	COG2252	PERMEase
DV160_RS04640	COG0372	Belongs to the citrate synthase family
DV160_RS04650	COG5505	Protein of unknown function (DUF819)
DV160_RS04660	COG2828	Protein conserved in bacteria
DV160_RS04670	COG0009	L-threonylcarbamoyladenylate synthase
DV160_RS04675	COG1959	2 iron, 2 sulfur cluster binding
DV160_RS04690	COG0287	Prephenate dehydrogenase
DV160_RS04695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DV160_RS04775	COG0697	spore germination
DV160_RS04785	COG2814	Major facilitator Superfamily
DV160_RS04865	COG0802	atpase or kinase
DV160_RS04975	COG0471	metal ion transport
DV160_RS04980	COG1376	ErfK ybiS ycfS ynhG family protein
DV160_RS04985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DV160_RS04995	COG2830	Protein of unknown function (DUF452)
DV160_RS05000	COG0500	methyltransferase
DV160_RS05080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DV160_RS05085	COG1538	Outer membrane efflux protein
DV160_RS05100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DV160_RS05110	COG2999	glutathione oxidoreductase activity
DV160_RS05135	COG1994	Peptidase M50
DV160_RS05160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DV160_RS05160	COG3453	Protein conserved in bacteria
DV160_RS05170	COG3278	Belongs to the heme-copper respiratory oxidase family
DV160_RS05185	COG2010	Cytochrome c
DV160_RS05200	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DV160_RS05205	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DV160_RS05245	COG1620	l-lactate permease
DV160_RS05270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DV160_RS05290	COG0733	neurotransmitter:sodium symporter activity
DV160_RS05320	COG3676	manually curated
DV160_RS05355	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DV160_RS05370	COG0586	Pfam SNARE associated Golgi protein
DV160_RS05375	COG0252	asparaginase activity
DV160_RS05390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DV160_RS05435	COG3245	cytochrome
DV160_RS05480	COG3008	intermembrane lipid transfer
DV160_RS05480	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DV160_RS05485	COG2995	paraquat-inducible protein a
DV160_RS05525	COG0826	peptidase U32
DV160_RS05535	COG0561	phosphatase activity
DV160_RS05555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DV160_RS05560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DV160_RS05600	COG1555	photosystem II stabilization
DV160_RS05600	COG1596	polysaccharide export
DV160_RS05675	COG1115	amino acid carrier protein
DV160_RS05680	COG1272	protein, Hemolysin III
DV160_RS05690	COG1160	GTP binding
DV160_RS05730	COG2194	sulfuric ester hydrolase activity
DV160_RS05735	COG0778	Nitroreductase
DV160_RS05765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DV160_RS05790	COG1619	proteins homologs of microcin C7 resistance protein MccF
DV160_RS05830	COG0351	phosphomethylpyrimidine kinase
DV160_RS05850	COG0569	domain protein
DV160_RS05920	COG5002	protein histidine kinase activity
DV160_RS05940	COG1275	C4-dicarboxylate transporter malic acid transport protein
DV160_RS05955	COG3547	Transposase (IS116 IS110 IS902 family)
DV160_RS06010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DV160_RS06020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DV160_RS06055	COG0616	signal peptide processing
DV160_RS06085	COG2084	Dehydrogenase
DV160_RS06115	COG1999	signal sequence binding
DV160_RS06125	COG0028	Belongs to the TPP enzyme family
DV160_RS06150	COG1049	propionate catabolic process, 2-methylcitrate cycle
DV160_RS06180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DV160_RS06190	COG1765	OsmC-like protein
DV160_RS06200	COG1802	Transcriptional regulator
DV160_RS06205	COG2431	L-lysine efflux transmembrane transporter activity
DV160_RS06210	COG1349	DNA-binding transcription factor activity
DV160_RS06250	COG0318	PFAM AMP-dependent synthetase and ligase
DV160_RS06360	COG3945	hemerythrin HHE cation binding domain
DV160_RS06385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DV160_RS06395	COG0859	PFAM glycosyl transferase family 9
DV160_RS06415	COG0277	FAD linked oxidase domain protein
DV160_RS06430	COG1562	ergosterol biosynthetic process
DV160_RS06495	COG0765	amino acid transport
DV160_RS06550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DV160_RS06630	COG1966	Carbon starvation protein
DV160_RS06680	COG1253	flavin adenine dinucleotide binding
DV160_RS06695	COG1607	acyl-coa hydrolase
DV160_RS06735	COG1942	4-Oxalocrotonate Tautomerase
DV160_RS06740	COG0436	Aminotransferase
DV160_RS06815	COG1943	Transposase
DV160_RS06835	COG0739	heme binding
DV160_RS06835	COG0741	lytic transglycosylase activity
DV160_RS06835	COG1196	nuclear chromosome segregation
DV160_RS06840	COG2814	Major facilitator Superfamily
DV160_RS06855	COG0697	spore germination
DV160_RS06865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DV160_RS06880	COG0348	domain, Protein
DV160_RS06890	COG2070	2-Nitropropane dioxygenase
DV160_RS06935	COG0210	DNA helicase
DV160_RS06985	COG2233	PERMEase
DV160_RS07035	COG2813	Specifically methylates the guanine in position
DV160_RS07035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DV160_RS07075	COG0678	peroxiredoxin activity
DV160_RS07075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DV160_RS07105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DV160_RS07125	COG0567	Dehydrogenase, E1 component
DV160_RS07130	COG0508	dehydrogenase complex catalyzes the overall conversion of
DV160_RS07140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DV160_RS07160	COG1943	Transposase
DV160_RS07265	COG2249	NAD(P)H dehydrogenase (quinone) activity
DV160_RS07270	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DV160_RS07280	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DV160_RS07290	COG0560	Phosphoserine phosphatase
DV160_RS07405	COG1773	rubredoxin
DV160_RS07430	COG0277	FAD linked oxidase domain protein
DV160_RS07550	COG2801	Transposase and inactivated derivatives
DV160_RS07585	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DV160_RS07595	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DV160_RS07615	COG0488	(ABC) transporter
DV160_RS07620	COG0586	Pfam SNARE associated Golgi protein
DV160_RS07635	COG0405	Gamma-glutamyltransferase
DV160_RS07650	COG2841	Protein conserved in bacteria
DV160_RS07660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DV160_RS07675	COG0494	nUDIX hydrolase
DV160_RS07740	COG3012	SEC-C Motif Domain Protein
DV160_RS07740	COG3318	Belongs to the UPF0149 family
DV160_RS07750	COG2866	Carboxypeptidase
DV160_RS07780	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DV160_RS07785	COG4178	(ABC) transporter
DV160_RS07865	COG3093	addiction module antidote protein HigA
DV160_RS07885	COG3392	D12 class N6 adenine-specific DNA methyltransferase
DV160_RS07890	COG4178	(ABC) transporter
DV160_RS07920	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DV160_RS07930	COG1562	ergosterol biosynthetic process
DV160_RS07955	COG0633	Ferredoxin
DV160_RS07970	COG2975	iron-sulfur cluster assembly
DV160_RS07975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DV160_RS07990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DV160_RS08010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DV160_RS08060	COG2895	sulfate adenylyltransferase (ATP) activity
DV160_RS08090	COG1217	gtp-binding protein TYPA
DV160_RS08115	COG0557	exoribonuclease II activity
DV160_RS08180	COG0628	permease
DV160_RS08190	COG0330	HflC and HflK could
DV160_RS08260	COG0488	(ABC) transporter
DV160_RS08285	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DV160_RS08300	COG2890	protein-(glutamine-N5) methyltransferase activity
DV160_RS08335	COG1393	Belongs to the ArsC family
DV160_RS08340	COG0488	(ABC) transporter
DV160_RS08360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DV160_RS08380	COG3850	Histidine kinase
DV160_RS08385	COG2197	response regulator
DV160_RS08420	COG1216	Glycosyl transferase, family 2
DV160_RS08440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DV160_RS08460	COG0583	DNA-binding transcription factor activity
DV160_RS08495	COG2217	Heavy metal translocating P-type atpase
DV160_RS08500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DV160_RS08510	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DV160_RS08570	COG2353	YceI-like domain
DV160_RS08575	COG1027	Aspartate ammonia-lyase
DV160_RS08580	COG0697	spore germination
DV160_RS08595	COG0251	oxidation-reduction process
DV160_RS08620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DV160_RS08625	COG0523	cobalamin synthesis protein
DV160_RS08635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DV160_RS08650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DV160_RS08650	COG4797	methyltransferase
DV160_RS08660	COG2608	mercury ion transmembrane transporter activity
DV160_RS08690	COG0318	PFAM AMP-dependent synthetase and ligase
DV160_RS08695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DV160_RS08710	COG2951	lytic endotransglycosylase activity
DV160_RS08730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DV160_RS08760	COG0633	Ferredoxin
DV160_RS08770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DV160_RS08780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DV160_RS08815	COG0741	lytic transglycosylase activity
DV160_RS08815	COG1388	LysM domain
DV160_RS08845	COG0789	Transcriptional regulator
DV160_RS08850	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DV160_RS08855	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DV160_RS08860	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DV160_RS08920	COG1183	phosphatidylcholine synthase activity
DV160_RS08925	COG0730	response to heat
DV160_RS08955	COG0492	ferredoxin-NADP+ reductase activity
DV160_RS08960	COG2217	Heavy metal translocating P-type atpase
DV160_RS08995	COG0793	Belongs to the peptidase S41A family
DV160_RS09010	COG3045	CreA protein
DV160_RS09025	COG0179	Fumarylacetoacetate (FAA) hydrolase
DV160_RS09040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DV160_RS09045	COG0508	dehydrogenase complex catalyzes the overall conversion of
DV160_RS09050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DV160_RS09085	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DV160_RS09095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DV160_RS09095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DV160_RS09120	COG1012	belongs to the aldehyde dehydrogenase family
DV160_RS09125	COG2095	MarC family integral membrane protein
DV160_RS09140	COG2990	Protein conserved in bacteria
DV160_RS09150	COG0543	2 iron, 2 sulfur cluster binding
DV160_RS09150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DV160_RS09180	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DV160_RS09210	COG0513	Belongs to the DEAD box helicase family
DV160_RS09265	COG3421	Type III restriction
DV160_RS09270	COG1304	FMN binding
DV160_RS09290	COG0822	iron-sulfur transferase activity
DV160_RS09300	COG3036	rescue of stalled ribosome
DV160_RS09345	COG1737	Transcriptional regulator
DV160_RS09360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DV160_RS09370	COG0800	Aldolase
DV160_RS09385	COG1194	a g-specific adenine glycosylase
DV160_RS09415	COG3676	manually curated
DV160_RS09440	COG0308	aminopeptidase N
DV160_RS09455	COG1560	Kdo2-lipid A biosynthetic process
DV160_RS09470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DV160_RS09480	COG0513	Belongs to the DEAD box helicase family
DV160_RS09540	COG0791	NLP P60 protein
DV160_RS09550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DV160_RS09555	COG0477	Major facilitator Superfamily
DV160_RS09560	COG0247	lactate metabolic process
DV160_RS09570	COG1139	Iron-sulfur cluster binding protein
DV160_RS09575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DV160_RS09600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DV160_RS09685	COG1607	acyl-coa hydrolase
DV160_RS09690	COG4221	oxidoreductase activity
DV160_RS09735	COG1192	Involved in chromosome partitioning
DV160_RS09880	COG1196	nuclear chromosome segregation
DV160_RS10030	COG0582	viral genome integration into host DNA
DV160_RS10055	COG0436	Aminotransferase
DV160_RS10115	COG0305	Participates in initiation and elongation during chromosome replication
DV160_RS10125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DV160_RS10130	COG1755	Isoprenylcysteine carboxyl methyltransferase
DV160_RS10145	COG4208	sulfate ABC transporter
DV160_RS10155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DV160_RS10165	COG1686	Belongs to the peptidase S11 family
DV160_RS10355	COG1702	phosphate starvation-inducible protein PhoH
DV160_RS10390	COG0312	modulator of DNA gyrase
DV160_RS10395	COG1278	Cold shock
DV160_RS10425	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DV160_RS10425	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DV160_RS10480	COG1309	transcriptional regulator
DV160_RS10485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DV160_RS10500	COG1187	pseudouridine synthase activity
DV160_RS10505	COG0778	Nitroreductase
DV160_RS10515	COG0626	cystathionine gamma-synthase activity
DV160_RS10535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DV160_RS10540	COG2867	negative regulation of translational initiation
DV160_RS10570	COG0471	metal ion transport
DV160_RS10575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DV160_RS10585	COG1126	abc transporter atp-binding protein
DV160_RS10590	COG0765	amino acid transport
DV160_RS10595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DV160_RS10605	COG2837	iron assimilation
DV160_RS10610	COG1074	ATP-dependent DNA helicase activity
DV160_RS10675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DV160_RS10685	COG0084	hydrolase, TatD family'
DV160_RS10705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DV160_RS10715	COG0681	Belongs to the peptidase S26 family
DV160_RS10805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DV160_RS10825	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DV160_RS10835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DV160_RS10855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DV160_RS10855	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DV160_RS10875	COG0497	DNA recombination
DV160_RS10880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DV160_RS10885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DV160_RS10920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DV160_RS10920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DV160_RS11050	COG1561	YicC-like family, N-terminal region
DV160_RS11065	COG1466	dna polymerase III delta subunit
DV160_RS11070	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
DV160_RS11085	COG0385	Bile acid
DV160_RS11140	COG1126	abc transporter atp-binding protein
DV160_RS11155	COG0285	dihydrofolate synthase activity
DV160_RS11170	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DV160_RS11255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DV160_RS11310	COG0281	malic enzyme
DV160_RS11310	COG0280	phosphate acetyltransferase
DV160_RS11320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DV160_RS11345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DV160_RS11490	COG2732	(Barnase) inhibitor
DV160_RS11515	COG0494	nUDIX hydrolase
DV160_RS11535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DV160_RS11560	COG1178	ABC-type Fe3 transport system permease component
DV160_RS11570	COG0280	phosphate acetyltransferase
DV160_RS11570	COG0857	belongs to the CobB CobQ family
DV160_RS11600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DV160_RS11630	COG2833	Protein of unknown function (DUF455)
DV160_RS11685	COG0004	ammonium transporteR
DV160_RS11690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DV160_RS11700	COG1177	transmembrane transport
DV160_RS11705	COG1176	ABC-type spermidine putrescine transport system, permease component I
DV160_RS11710	COG3842	ATPase activity
DV160_RS11720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DV160_RS11725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DV160_RS11730	COG1862	Preprotein translocase
DV160_RS11735	COG0123	including yeast histone deacetylase and acetoin utilization protein
DV160_RS11740	COG1063	alcohol dehydrogenase
DV160_RS11765	COG0805	protein transport
DV160_RS11785	COG0745	RESPONSE REGULATOR receiver
DV160_RS11790	COG2205	protein histidine kinase activity
DV160_RS11825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DV160_RS11830	COG0803	Belongs to the bacterial solute-binding protein 9 family
DV160_RS11850	COG3676	manually curated
DV160_RS11860	COG0644	oxidoreductase
DV160_RS11860	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DV160_RS11905	COG1522	sequence-specific DNA binding
DV160_RS11915	COG2832	Protein of unknown function (DUF454)
DV160_RS11960	COG1477	protein flavinylation
DV160_RS11965	COG2991	Protein conserved in bacteria
DV160_RS11975	COG1045	serine acetyltransferase
DV160_RS12035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DV160_RS12040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DV160_RS12055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DV160_RS12065	COG1064	alcohol dehydrogenase
DV160_RS12075	COG1196	nuclear chromosome segregation
DV160_RS12095	COG1620	l-lactate permease
DV160_RS12110	COG1448	Aminotransferase
DV160_RS12135	COG1757	Na H antiporter
DV160_RS12165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DV160_RS12170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DV160_RS12175	COG1757	Na H antiporter
DV160_RS12195	COG3759	membrane
DV160_RS12200	COG0720	synthase
DV160_RS12320	COG2831	hemolysin activation secretion protein
DV160_RS12385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DV160_RS12400	COG1530	ribonuclease E activity
DV160_RS12405	COG5000	phosphorelay sensor kinase activity
DV160_RS12420	COG2851	Citrate transporter
DV160_RS12425	COG0431	NADPH-dependent FMN reductase
DV160_RS12465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DV160_RS12470	COG1333	cytochrome c biogenesis protein
DV160_RS12550	COG0121	glutamine amidotransferase
DV160_RS12560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DV160_RS12560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DV160_RS12580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DV160_RS12600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DV160_RS12610	COG3977	Valine--pyruvate aminotransferase
DV160_RS12615	COG0613	PHP domain protein
DV160_RS12685	COG0196	riboflavin kinase activity
DV160_RS12710	COG0012	GTP binding
DV160_RS12745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DV160_RS12755	COG0489	protein tyrosine kinase activity
DV160_RS12805	COG2852	Protein conserved in bacteria
DV160_RS12830	COG0583	DNA-binding transcription factor activity
DV160_RS12840	COG2249	NAD(P)H dehydrogenase (quinone) activity
DV160_RS12860	COG0511	ligase activity, forming carbon-carbon bonds
DV160_RS12865	COG0439	Biotin carboxylase
DV160_RS12950	COG1505	serine-type exopeptidase activity