locus-tag	class	description
FOC66_RS00035	COG0142	geranyltranstransferase activity
FOC66_RS00100	COG1994	Peptidase M50
FOC66_RS00105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC66_RS00120	COG0697	spore germination
FOC66_RS00175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC66_RS00180	COG0009	L-threonylcarbamoyladenylate synthase
FOC66_RS00195	COG0308	aminopeptidase N
FOC66_RS00215	COG0440	acetolactate synthase activity
FOC66_RS00220	COG0028	Belongs to the TPP enzyme family
FOC66_RS00230	COG1999	signal sequence binding
FOC66_RS00255	COG0287	Prephenate dehydrogenase
FOC66_RS00310	COG1555	photosystem II stabilization
FOC66_RS00325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC66_RS00365	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOC66_RS00375	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOC66_RS00385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC66_RS00405	COG2975	iron-sulfur cluster assembly
FOC66_RS00455	COG2951	lytic endotransglycosylase activity
FOC66_RS00465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC66_RS00525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC66_RS00540	COG0567	Dehydrogenase, E1 component
FOC66_RS00545	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC66_RS00550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC66_RS00570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC66_RS00575	COG1061	Type III restriction enzyme res subunit
FOC66_RS00580	COG1002	Type II restriction enzyme, methylase subunits
FOC66_RS00610	COG0662	Cupin 2, conserved barrel domain protein
FOC66_RS00635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC66_RS00640	COG2217	Heavy metal translocating P-type atpase
FOC66_RS00685	COG1561	YicC-like family, N-terminal region
FOC66_RS00695	COG0385	Bile acid
FOC66_RS00705	COG0730	response to heat
FOC66_RS00715	COG1902	pentaerythritol trinitrate reductase activity
FOC66_RS00720	COG1063	alcohol dehydrogenase
FOC66_RS00725	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC66_RS00730	COG1862	Preprotein translocase
FOC66_RS00735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC66_RS00740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC66_RS00750	COG0778	Nitroreductase
FOC66_RS00780	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC66_RS00815	COG1247	-acetyltransferase
FOC66_RS00875	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC66_RS00895	COG0800	Aldolase
FOC66_RS00905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC66_RS00920	COG1737	Transcriptional regulator
FOC66_RS00940	COG1116	anion transmembrane transporter activity
FOC66_RS00980	COG3275	phosphorelay sensor kinase activity
FOC66_RS00985	COG1049	propionate catabolic process, 2-methylcitrate cycle
FOC66_RS00990	COG0513	Belongs to the DEAD box helicase family
FOC66_RS01005	COG1686	Belongs to the peptidase S11 family
FOC66_RS01010	COG0501	Belongs to the peptidase M48B family
FOC66_RS01045	COG0857	belongs to the CobB CobQ family
FOC66_RS01045	COG0280	phosphate acetyltransferase
FOC66_RS01075	COG0084	hydrolase, TatD family'
FOC66_RS01080	COG0252	asparaginase activity
FOC66_RS01085	COG0586	Pfam SNARE associated Golgi protein
FOC66_RS01105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FOC66_RS01145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC66_RS01175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC66_RS01185	COG1530	ribonuclease E activity
FOC66_RS01205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC66_RS01210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC66_RS01225	COG1196	nuclear chromosome segregation
FOC66_RS01235	COG0438	transferase activity, transferring glycosyl groups
FOC66_RS01240	COG0312	modulator of DNA gyrase
FOC66_RS01270	COG0697	spore germination
FOC66_RS01300	COG1064	alcohol dehydrogenase
FOC66_RS01305	COG0564	pseudouridine synthase activity
FOC66_RS01340	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC66_RS01360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC66_RS01380	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOC66_RS01385	COG0497	DNA recombination
FOC66_RS01410	COG0318	PFAM AMP-dependent synthetase and ligase
FOC66_RS01460	COG0175	sulfate reduction
FOC66_RS01465	COG1272	protein, Hemolysin III
FOC66_RS01470	COG1115	amino acid carrier protein
FOC66_RS01550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOC66_RS01555	COG1610	YqeY-like protein
FOC66_RS01575	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC66_RS01595	COG0601	transmembrane transport
FOC66_RS01600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC66_RS01605	COG4172	Belongs to the ABC transporter superfamily
FOC66_RS01635	COG0277	FAD linked oxidase domain protein
FOC66_RS01655	COG1523	belongs to the glycosyl hydrolase 13 family
FOC66_RS01660	COG0058	SHG alpha-glucan phosphorylase activity
FOC66_RS01680	COG0802	atpase or kinase
FOC66_RS01690	COG1690	Belongs to the RtcB family
FOC66_RS01695	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FOC66_RS01715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC66_RS01715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC66_RS01725	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FOC66_RS01740	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOC66_RS01745	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOC66_RS01765	COG4172	Belongs to the ABC transporter superfamily
FOC66_RS01770	COG0318	PFAM AMP-dependent synthetase and ligase
FOC66_RS01775	COG0084	hydrolase, TatD family'
FOC66_RS01825	COG4221	oxidoreductase activity
FOC66_RS01835	COG0523	cobalamin synthesis protein
FOC66_RS01840	COG4174	ABC transporter (Permease)
FOC66_RS01845	COG4239	(ABC) transporter, permease
FOC66_RS01855	COG0730	response to heat
FOC66_RS01860	COG1183	phosphatidylcholine synthase activity
FOC66_RS01925	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOC66_RS01925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC66_RS01970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC66_RS01990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOC66_RS02005	COG1278	Cold shock
FOC66_RS02030	COG0492	ferredoxin-NADP+ reductase activity
FOC66_RS02035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC66_RS02040	COG1177	transmembrane transport
FOC66_RS02045	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC66_RS02050	COG3842	ATPase activity
FOC66_RS02105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOC66_RS02105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOC66_RS02120	COG0248	Ppx GppA phosphatase
FOC66_RS02130	COG2814	Major facilitator Superfamily
FOC66_RS02195	COG2866	Carboxypeptidase
FOC66_RS02205	COG0569	domain protein
FOC66_RS02210	COG0471	metal ion transport
FOC66_RS02220	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC66_RS02240	COG2116	formate transmembrane transporter activity
FOC66_RS02245	COG1607	acyl-coa hydrolase
FOC66_RS02305	COG1518	maintenance of DNA repeat elements
FOC66_RS02310	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FOC66_RS02320	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FOC66_RS02325	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FOC66_RS02330	COG4650	regulator
FOC66_RS02350	COG0698	ribose 5-phosphate isomerase
FOC66_RS02360	COG0494	nUDIX hydrolase
FOC66_RS02390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOC66_RS02395	COG2076	Multidrug Resistance protein
FOC66_RS02415	COG2895	sulfate adenylyltransferase (ATP) activity
FOC66_RS02415	COG0529	Catalyzes the synthesis of activated sulfate
FOC66_RS02430	COG2841	Protein conserved in bacteria
FOC66_RS02435	COG4771	TonB-dependent receptor
FOC66_RS02440	COG0778	Nitroreductase
FOC66_RS02445	COG1027	Aspartate ammonia-lyase
FOC66_RS02465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC66_RS02480	COG0640	Transcriptional regulator
FOC66_RS02485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC66_RS02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC66_RS02520	COG2959	enzyme of heme biosynthesis
FOC66_RS02530	COG1132	(ABC) transporter
FOC66_RS02545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC66_RS02560	COG1253	flavin adenine dinucleotide binding
FOC66_RS02595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC66_RS02600	COG1309	transcriptional regulator
FOC66_RS02620	COG0824	Thioesterase
FOC66_RS02635	COG4178	(ABC) transporter
FOC66_RS02640	COG4774	siderophore transport
FOC66_RS02645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC66_RS02680	COG1234	tRNA 3'-trailer cleavage
FOC66_RS02705	COG2353	YceI-like domain
FOC66_RS02710	COG0385	Bile acid
FOC66_RS02745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC66_RS02770	COG1028	Short-chain dehydrogenase reductase Sdr
FOC66_RS02775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC66_RS02825	COG1882	Formate acetyltransferase
FOC66_RS02830	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC66_RS02840	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FOC66_RS02860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC66_RS02860	COG1648	precorrin-2 dehydrogenase activity
FOC66_RS02915	COG3036	rescue of stalled ribosome
FOC66_RS02930	COG0822	iron-sulfur transferase activity
FOC66_RS02955	COG1304	FMN binding
FOC66_RS02970	COG0626	cystathionine gamma-synthase activity
FOC66_RS02985	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOC66_RS03005	COG1562	ergosterol biosynthetic process
FOC66_RS03015	COG0408	coproporphyrinogen oxidase activity
FOC66_RS03020	COG0791	NLP P60 protein
FOC66_RS03025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC66_RS03050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC66_RS03075	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC66_RS03090	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC66_RS03110	COG0617	tRNA 3'-terminal CCA addition
FOC66_RS03140	COG1702	phosphate starvation-inducible protein PhoH
FOC66_RS03160	COG2304	oxidoreductase activity
FOC66_RS03195	COG1733	regulation of RNA biosynthetic process
FOC66_RS03220	COG0210	DNA helicase
FOC66_RS03225	COG0167	dihydroorotate dehydrogenase activity
FOC66_RS03240	COG0513	Belongs to the DEAD box helicase family
FOC66_RS03290	COG0598	Magnesium transport protein CorA
FOC66_RS03295	COG1607	acyl-coa hydrolase
FOC66_RS03315	COG1584	GPR1 FUN34 yaaH family protein
FOC66_RS03320	COG0633	Ferredoxin
FOC66_RS03325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC66_RS03335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC66_RS03345	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC66_RS03385	COG0372	Belongs to the citrate synthase family
FOC66_RS03395	COG2828	Protein conserved in bacteria
FOC66_RS03410	COG0628	permease
FOC66_RS03440	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOC66_RS03450	COG1125	glycine betaine transport
FOC66_RS03450	COG0517	IMP dehydrogenase activity
FOC66_RS03510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC66_RS03515	COG4558	Periplasmic binding protein
FOC66_RS03520	COG4771	TonB-dependent receptor
FOC66_RS03525	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC66_RS03530	COG2207	Transcriptional regulator
FOC66_RS03685	COG3384	dioxygenase
FOC66_RS03710	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC66_RS03720	COG3850	Histidine kinase
FOC66_RS03725	COG2197	response regulator
FOC66_RS03735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC66_RS03755	COG0488	(ABC) transporter
FOC66_RS03775	COG4208	sulfate ABC transporter
FOC66_RS03785	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOC66_RS03795	COG0330	HflC and HflK could
FOC66_RS03815	COG2233	PERMEase
FOC66_RS03830	COG1139	Iron-sulfur cluster binding protein
FOC66_RS03840	COG0247	lactate metabolic process
FOC66_RS03850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC66_RS03855	COG0765	amino acid transport
FOC66_RS03860	COG1126	abc transporter atp-binding protein
FOC66_RS03865	COG0488	(ABC) transporter
FOC66_RS03915	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC66_RS03920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC66_RS03940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOC66_RS03945	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC66_RS03950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC66_RS03960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC66_RS03965	COG3738	Protein conserved in bacteria
FOC66_RS03990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOC66_RS04020	COG0697	spore germination
FOC66_RS04025	COG0484	heat shock protein binding
FOC66_RS04035	COG0251	oxidation-reduction process
FOC66_RS04050	COG1629	transport
FOC66_RS04050	COG4774	siderophore transport
FOC66_RS04070	COG3012	SEC-C Motif Domain Protein
FOC66_RS04070	COG3318	Belongs to the UPF0149 family
FOC66_RS04075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC66_RS04100	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC66_RS04110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC66_RS04140	COG1393	Belongs to the ArsC family
FOC66_RS04145	COG0557	exoribonuclease II activity
FOC66_RS04195	COG1187	pseudouridine synthase activity
FOC66_RS04200	COG0733	neurotransmitter:sodium symporter activity
FOC66_RS04205	COG0277	FAD linked oxidase domain protein
FOC66_RS04245	COG1943	Transposase
FOC66_RS04270	COG2233	PERMEase
FOC66_RS04300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC66_RS04330	COG2867	negative regulation of translational initiation
FOC66_RS04360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOC66_RS04380	COG1426	Protein conserved in bacteria
FOC66_RS04390	COG3739	integral membrane protein
FOC66_RS04400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC66_RS04405	COG0305	Participates in initiation and elongation during chromosome replication
FOC66_RS04470	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FOC66_RS04475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC66_RS04505	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC66_RS04535	COG2217	Heavy metal translocating P-type atpase
FOC66_RS04540	COG2608	mercury ion transmembrane transporter activity
FOC66_RS04545	COG2814	Major facilitator Superfamily
FOC66_RS04550	COG0471	metal ion transport
FOC66_RS04555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC66_RS04560	COG1881	PFAM PEBP family protein
FOC66_RS04565	COG2321	neutral zinc metallopeptidase
FOC66_RS04575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC66_RS04590	COG0307	riboflavin synthase, alpha
FOC66_RS04595	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOC66_RS04610	COG0859	PFAM glycosyl transferase family 9
FOC66_RS04625	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC66_RS04630	COG0463	Glycosyl transferase, family 2
FOC66_RS04675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC66_RS04680	COG2813	Specifically methylates the guanine in position
FOC66_RS04680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC66_RS04695	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOC66_RS04715	COG2854	intermembrane phospholipid transfer
FOC66_RS04720	COG1942	4-Oxalocrotonate Tautomerase
FOC66_RS04725	COG0436	Aminotransferase
FOC66_RS04735	COG3568	Endonuclease Exonuclease Phosphatase
FOC66_RS04750	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC66_RS04755	COG0586	Pfam SNARE associated Golgi protein
FOC66_RS04760	COG1696	Membrane protein involved in D-alanine export
FOC66_RS04780	COG1408	metallophosphoesterase
FOC66_RS04785	COG2837	iron assimilation
FOC66_RS04800	COG1074	ATP-dependent DNA helicase activity
FOC66_RS04815	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOC66_RS04820	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
FOC66_RS04865	COG0494	nUDIX hydrolase
FOC66_RS04905	COG0285	dihydrofolate synthase activity
FOC66_RS04920	COG1126	abc transporter atp-binding protein
FOC66_RS04940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC66_RS04950	COG0681	Belongs to the peptidase S26 family
FOC66_RS04960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC66_RS04975	COG0678	peroxiredoxin activity
FOC66_RS04975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC66_RS04995	COG0741	lytic transglycosylase activity
FOC66_RS04995	COG1388	LysM domain
FOC66_RS05025	COG1077	Cell shape determining protein MreB Mrl
FOC66_RS05030	COG1792	Involved in formation and maintenance of cell shape
FOC66_RS05040	COG0768	penicillin binding
FOC66_RS05045	COG0772	Belongs to the SEDS family
FOC66_RS05055	COG1012	belongs to the aldehyde dehydrogenase family
FOC66_RS05060	COG0280	phosphate acetyltransferase
FOC66_RS05060	COG0281	malic enzyme
FOC66_RS05070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC66_RS05125	COG0196	riboflavin kinase activity
FOC66_RS05140	COG2885	chlorophyll binding
FOC66_RS05145	COG2070	2-Nitropropane dioxygenase
FOC66_RS05155	COG1773	rubredoxin
FOC66_RS05185	COG3045	CreA protein
FOC66_RS05195	COG0793	Belongs to the peptidase S41A family
FOC66_RS05265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC66_RS05280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC66_RS05320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC66_RS05320	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC66_RS05460	COG4942	peptidase
FOC66_RS05485	COG1966	Carbon starvation protein
FOC66_RS05490	COG1187	pseudouridine synthase activity
FOC66_RS05505	COG1160	GTP binding
FOC66_RS05530	COG0488	(ABC) transporter
FOC66_RS05545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC66_RS05580	COG2814	Major facilitator Superfamily
FOC66_RS05585	COG0433	COG0433 Predicted ATPase
FOC66_RS05610	COG0187	DNA topoisomerase II activity
FOC66_RS05660	COG1045	serine acetyltransferase
FOC66_RS05670	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOC66_RS05670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC66_RS05685	COG2995	paraquat-inducible protein a
FOC66_RS05690	COG3008	intermembrane lipid transfer
FOC66_RS05690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOC66_RS05700	COG2999	glutathione oxidoreductase activity
FOC66_RS05705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC66_RS05710	COG2116	formate transmembrane transporter activity
FOC66_RS05725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC66_RS05750	COG1448	Aminotransferase
FOC66_RS05765	COG2833	Protein of unknown function (DUF455)
FOC66_RS05780	COG3245	cytochrome
FOC66_RS05805	COG0733	neurotransmitter:sodium symporter activity
FOC66_RS05835	COG2967	ApaG domain
FOC66_RS05840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC66_RS05850	COG0300	oxidoreductase activity
FOC66_RS05855	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FOC66_RS05865	COG1555	photosystem II stabilization
FOC66_RS05900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC66_RS05935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC66_RS05945	COG1538	Outer membrane efflux protein
FOC66_RS05950	COG2354	Protein conserved in bacteria
FOC66_RS05970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC66_RS05975	COG1757	Na H antiporter
FOC66_RS05985	COG0765	amino acid transport
FOC66_RS06010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC66_RS06015	COG2011	ABC-type metal ion transport system permease component
FOC66_RS06020	COG1464	Belongs to the NlpA lipoprotein family
FOC66_RS06035	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC66_RS06050	COG4263	nitrous-oxide reductase activity
FOC66_RS06080	COG2350	Protein conserved in bacteria
FOC66_RS06105	COG3265	gluconokinase activity
FOC66_RS06110	COG2610	gluconate transmembrane transporter activity
FOC66_RS06120	COG0805	protein transport
FOC66_RS06190	COG0745	RESPONSE REGULATOR receiver
FOC66_RS06195	COG2205	protein histidine kinase activity
FOC66_RS06245	COG0583	DNA-binding transcription factor activity
FOC66_RS06250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC66_RS06255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC66_RS06260	COG3313	Fe-S protein
FOC66_RS06275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC66_RS06290	COG3945	hemerythrin HHE cation binding domain
FOC66_RS06370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC66_RS06375	COG1376	ErfK ybiS ycfS ynhG family protein
FOC66_RS06385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC66_RS06400	COG0631	protein serine/threonine phosphatase activity
FOC66_RS06405	COG2267	carboxylic ester hydrolase activity
FOC66_RS06410	COG0671	phosphoesterase, PA-phosphatase related
FOC66_RS06410	COG2453	phosphatase
FOC66_RS06425	COG4589	Belongs to the CDS family
FOC66_RS06435	COG0826	peptidase U32
FOC66_RS06440	COG0826	peptidase U32
FOC66_RS06445	COG3154	lipid carrier protein
FOC66_RS06450	COG2010	Cytochrome c
FOC66_RS06465	COG3278	Belongs to the heme-copper respiratory oxidase family
FOC66_RS06500	COG1522	sequence-specific DNA binding
FOC66_RS06510	COG2832	Protein of unknown function (DUF454)
FOC66_RS06550	COG1477	protein flavinylation
FOC66_RS06555	COG2991	Protein conserved in bacteria
FOC66_RS06570	COG1114	Component of the transport system for branched-chain amino acids
FOC66_RS06585	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC66_RS06610	COG2252	PERMEase
FOC66_RS06670	COG1765	OsmC-like protein
FOC66_RS06675	COG0351	phosphomethylpyrimidine kinase
FOC66_RS06685	COG0519	Catalyzes the synthesis of GMP from XMP
FOC66_RS06705	COG0038	chloride channel
FOC66_RS06715	COG1346	cytolysis
FOC66_RS06720	COG1380	Effector of murein hydrolase LrgA
FOC66_RS06725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC66_RS06730	COG0315	cyclic pyranopterin monophosphate synthase activity
FOC66_RS06740	COG0012	GTP binding
FOC66_RS06745	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOC66_RS06760	COG0791	NLP P60 protein
FOC66_RS06775	COG1760	l-serine dehydratase
FOC66_RS06795	COG0720	synthase
FOC66_RS06800	COG3759	membrane
FOC66_RS06810	COG1620	l-lactate permease
FOC66_RS06890	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC66_RS06905	COG1442	glycosyl transferase family 8
FOC66_RS06910	COG1028	Short-chain dehydrogenase reductase Sdr
FOC66_RS06940	COG2027	D-alanyl-D-alanine carboxypeptidase
FOC66_RS06945	COG0477	Major facilitator Superfamily
FOC66_RS06950	COG0431	NADPH-dependent FMN reductase
FOC66_RS07005	COG0613	PHP domain protein
FOC66_RS07010	COG0121	glutamine amidotransferase
FOC66_RS07015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOC66_RS07020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC66_RS07020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC66_RS07050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC66_RS07065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC66_RS07070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC66_RS07125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC66_RS07150	COG2962	Rard protein
FOC66_RS07160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC66_RS07165	COG1333	cytochrome c biogenesis protein
FOC66_RS07190	COG0583	DNA-binding transcription factor activity
FOC66_RS07230	COG0339	signal peptide processing
FOC66_RS07245	COG2954	triphosphatase activity
FOC66_RS07255	COG3245	cytochrome
FOC66_RS07265	COG0583	DNA-binding transcription factor activity
FOC66_RS07285	COG1442	glycosyl transferase family 8
FOC66_RS07335	COG0511	ligase activity, forming carbon-carbon bonds
FOC66_RS07345	COG0439	Biotin carboxylase
FOC66_RS07350	COG0753	catalase activity
FOC66_RS07365	COG1629	transport
FOC66_RS07370	COG4607	ABC-type enterochelin transport system periplasmic component
FOC66_RS07375	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC66_RS07380	COG4605	iron ion homeostasis
FOC66_RS07395	COG4604	ABC transporter, ATP-binding protein
FOC66_RS07400	COG3977	Valine--pyruvate aminotransferase
FOC66_RS07410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC66_RS07420	COG1560	Kdo2-lipid A biosynthetic process
FOC66_RS07440	COG0312	modulator of DNA gyrase
FOC66_RS07465	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC66_RS07490	COG0628	permease
FOC66_RS07495	COG0814	amino acid
FOC66_RS07530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC66_RS07550	COG4166	transmembrane transport
FOC66_RS07560	COG0708	Exodeoxyribonuclease III
FOC66_RS07585	COG1555	photosystem II stabilization
FOC66_RS07620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC66_RS07630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC66_RS07645	COG0708	Exodeoxyribonuclease III
FOC66_RS07745	COG2823	Periplasmic or secreted lipoprotein
FOC66_RS07755	COG0024	Methionine aminopeptidase
FOC66_RS07770	COG0671	phosphoesterase, PA-phosphatase related
FOC66_RS07775	COG1058	Belongs to the CinA family
FOC66_RS07775	COG1546	Belongs to the CinA family
FOC66_RS07830	COG1192	Involved in chromosome partitioning
FOC66_RS07835	COG2856	Zn peptidase
FOC66_RS07845	COG1643	Atp-dependent helicase
FOC66_RS07875	COG1643	Atp-dependent helicase
FOC66_RS07880	COG0799	negative regulation of ribosome biogenesis
FOC66_RS07890	COG0288	reversible hydration of carbon dioxide
FOC66_RS07900	COG3842	ATPase activity
FOC66_RS07925	COG1115	amino acid carrier protein
FOC66_RS07935	COG0415	Belongs to the DNA photolyase family
FOC66_RS07955	COG0583	DNA-binding transcription factor activity
FOC66_RS07970	COG0861	Integral membrane protein TerC family
FOC66_RS07985	COG1012	belongs to the aldehyde dehydrogenase family
FOC66_RS07995	COG1115	amino acid carrier protein
FOC66_RS08040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC66_RS08050	COG0201	protein transport
FOC66_RS08245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC66_RS08250	COG0742	ribosomal rna small subunit methyltransferase
FOC66_RS08270	COG0758	DNA mediated transformation
FOC66_RS08275	COG2204	response regulator
FOC66_RS08280	COG5000	phosphorelay sensor kinase activity
FOC66_RS08290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC66_RS08290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC66_RS08295	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FOC66_RS08320	COG0469	pyruvate kinase activity
FOC66_RS08360	COG1555	photosystem II stabilization
FOC66_RS08400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC66_RS08405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC66_RS08420	COG1289	transmembrane transporter activity
FOC66_RS08430	COG0612	Peptidase, M16
FOC66_RS08480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC66_RS08490	COG0668	transmembrane transport
FOC66_RS08495	COG1546	Belongs to the CinA family
FOC66_RS08510	COG0672	)-iron permease
FOC66_RS08530	COG2226	methyltransferase
FOC66_RS08540	COG1040	competence protein
FOC66_RS08545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC66_RS08605	COG1846	Transcriptional regulator
FOC66_RS08605	COG0456	acetyltransferase
FOC66_RS08610	COG1199	ATP-dependent helicase activity
FOC66_RS08620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC66_RS08625	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC66_RS08630	COG0405	Gamma-glutamyltransferase
FOC66_RS08650	COG1335	isochorismatase
FOC66_RS08655	COG0859	PFAM glycosyl transferase family 9
FOC66_RS08670	COG1739	Uncharacterized protein family UPF0029
FOC66_RS08710	COG0142	geranyltranstransferase activity
FOC66_RS08720	COG0557	exoribonuclease II activity
FOC66_RS08725	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC66_RS08775	COG2884	Cell division ATP-binding protein ftsE
FOC66_RS08780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC66_RS08825	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC66_RS08830	COG0514	ATP-dependent DNA helicase (RecQ)
FOC66_RS08835	COG2259	Doxx family
FOC66_RS08850	COG3219	Protein conserved in bacteria
FOC66_RS08855	COG1595	DNA-templated transcription, initiation
FOC66_RS08870	COG0729	surface antigen
FOC66_RS08880	COG1132	(ABC) transporter
FOC66_RS08885	COG1611	Belongs to the LOG family
FOC66_RS08900	COG3104	oligopeptide transport
FOC66_RS08905	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC66_RS08925	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FOC66_RS08940	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FOC66_RS09100	COG1297	OPT oligopeptide transporter protein
FOC66_RS09105	COG1519	Transferase
FOC66_RS09120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC66_RS09125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC66_RS09130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC66_RS09150	COG1178	ABC-type Fe3 transport system permease component
FOC66_RS09155	COG3038	cytochrome b561
FOC66_RS09165	COG0616	signal peptide processing
FOC66_RS09165	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOC66_RS09175	COG0786	glutamate:sodium symporter activity
FOC66_RS09220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC66_RS09225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC66_RS09240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC66_RS09240	COG1215	transferase activity, transferring glycosyl groups
FOC66_RS09285	COG2259	Doxx family
FOC66_RS09315	COG0824	Thioesterase
FOC66_RS09340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOC66_RS09345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC66_RS09350	COG1127	ABC transporter
FOC66_RS09390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC66_RS09395	COG1126	abc transporter atp-binding protein
FOC66_RS09405	COG0765	amino acid transport
FOC66_RS09425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC66_RS09435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC66_RS09445	COG1530	ribonuclease E activity
FOC66_RS09455	COG1970	mechanosensitive ion channel activity
FOC66_RS09470	COG1505	serine-type exopeptidase activity
FOC66_RS09490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC66_RS09505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOC66_RS09545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC66_RS09560	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC66_RS09600	COG2268	Band 7 protein
FOC66_RS09605	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC66_RS09620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC66_RS09620	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC66_RS09655	COG0210	DNA helicase
FOC66_RS09660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC66_RS09665	COG0733	neurotransmitter:sodium symporter activity
FOC66_RS09680	COG1346	cytolysis
FOC66_RS09685	COG1380	Effector of murein hydrolase LrgA
FOC66_RS09690	COG0583	DNA-binding transcription factor activity
FOC66_RS09695	COG2239	Acts as a magnesium transporter
FOC66_RS09725	COG0456	acetyltransferase
FOC66_RS09730	COG1214	PFAM Peptidase M22, glycoprotease
FOC66_RS09735	COG0625	glutathione transferase activity
FOC66_RS09745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC66_RS09810	COG0489	protein tyrosine kinase activity
FOC66_RS09825	COG1131	(ABC) transporter
FOC66_RS09840	COG2878	Part of a membrane complex involved in electron transport
FOC66_RS09850	COG3012	SEC-C Motif Domain Protein
FOC66_RS09860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC66_RS09910	COG2056	Na+-H+ antiporter family
FOC66_RS09915	COG0477	Major facilitator Superfamily
FOC66_RS09920	COG1012	belongs to the aldehyde dehydrogenase family
FOC66_RS09920	COG1454	alcohol dehydrogenase
FOC66_RS09935	COG2119	membrane
FOC66_RS09940	COG0564	pseudouridine synthase activity
FOC66_RS09945	COG0583	DNA-binding transcription factor activity
FOC66_RS09955	COG0723	plastoquinol--plastocyanin reductase activity
FOC66_RS09960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC66_RS09965	COG2857	Cytochrome c1
FOC66_RS09970	COG0625	glutathione transferase activity
FOC66_RS09975	COG2969	positive regulation of protein catabolic process
FOC66_RS10035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC66_RS10070	COG0154	amidase activity
FOC66_RS10125	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FOC66_RS10180	COG3279	Response regulator of the LytR AlgR family
FOC66_RS10200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOC66_RS10210	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOC66_RS10215	COG1137	ATPase activity
FOC66_RS10230	COG2814	Major facilitator Superfamily
FOC66_RS10240	COG1609	Transcriptional regulator
FOC66_RS10275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC66_RS10280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC66_RS10310	COG4178	(ABC) transporter
FOC66_RS10325	COG0560	Phosphoserine phosphatase
FOC66_RS10375	COG1216	Glycosyl transferase, family 2
FOC66_RS10410	COG0644	oxidoreductase
FOC66_RS10410	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FOC66_RS10425	COG1959	2 iron, 2 sulfur cluster binding
FOC66_RS10450	COG0142	geranyltranstransferase activity
FOC66_RS10470	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOC66_RS10480	COG0859	PFAM glycosyl transferase family 9
FOC66_RS10490	COG0739	heme binding
FOC66_RS10515	COG1994	Peptidase M50
FOC66_RS10520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC66_RS10535	COG0697	spore germination
FOC66_RS10585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC66_RS10590	COG0009	L-threonylcarbamoyladenylate synthase