locus-tag	class	description
NITSA_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NITSA_RS00010	COG0592	DNA-directed DNA polymerase activity
NITSA_RS00015	COG0504	CTP synthase activity
NITSA_RS00020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NITSA_RS00020	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NITSA_RS00035	COG1104	cysteine desulfurase activity
NITSA_RS00045	COG0544	peptidyl-prolyl cis-trans isomerase activity
NITSA_RS00050	COG0740	serine-type endopeptidase activity
NITSA_RS00055	COG0242	peptide deformylase activity
NITSA_RS00060	COG0606	chelatase, subunit chli
NITSA_RS00070	COG2855	membrane
NITSA_RS00075	COG0583	DNA-binding transcription factor activity
NITSA_RS00080	COG0746	molybdenum cofactor guanylyltransferase activity
NITSA_RS00105	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NITSA_RS00115	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NITSA_RS00135	COG1139	Iron-sulfur cluster binding protein
NITSA_RS00140	COG0247	lactate metabolic process
NITSA_RS00145	COG0778	Nitroreductase
NITSA_RS00150	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NITSA_RS00155	COG0237	dephospho-CoA kinase activity
NITSA_RS00160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NITSA_RS00210	COG0129	dihydroxy-acid dehydratase activity
NITSA_RS00215	COG1388	LysM domain
NITSA_RS00215	COG0791	NLP P60 protein
NITSA_RS00225	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NITSA_RS00230	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NITSA_RS00245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NITSA_RS00250	COG4796	Type ii and iii secretion system protein
NITSA_RS00280	COG2165	general secretion pathway protein
NITSA_RS00310	COG1187	pseudouridine synthase activity
NITSA_RS00315	COG0517	IMP dehydrogenase activity
NITSA_RS00315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NITSA_RS00325	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NITSA_RS00330	COG0107	imidazoleglycerol-phosphate synthase activity
NITSA_RS00340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NITSA_RS00345	COG0564	pseudouridine synthase activity
NITSA_RS00350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NITSA_RS00355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NITSA_RS00360	COG1459	type II secretion system
NITSA_RS00365	COG1309	transcriptional regulator
NITSA_RS00385	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NITSA_RS00390	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NITSA_RS00410	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NITSA_RS00420	COG0310	cobalt ion transport
NITSA_RS00435	COG1122	ATPase activity
NITSA_RS00440	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NITSA_RS00445	COG0298	carbon dioxide binding
NITSA_RS00450	COG0409	Hydrogenase expression formation protein
NITSA_RS00460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NITSA_RS00460	COG1024	Enoyl-CoA hydratase
NITSA_RS00505	COG0450	alkyl hydroperoxide reductase
NITSA_RS00520	COG0051	transcription antitermination factor activity, RNA binding
NITSA_RS00525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NITSA_RS00530	COG0088	Forms part of the polypeptide exit tunnel
NITSA_RS00535	COG0089	rRNA binding
NITSA_RS00540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NITSA_RS00545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NITSA_RS00550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NITSA_RS00555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NITSA_RS00560	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NITSA_RS00565	COG0255	Belongs to the universal ribosomal protein uL29 family
NITSA_RS00570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NITSA_RS00575	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NITSA_RS00580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NITSA_RS00585	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NITSA_RS00590	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NITSA_RS00595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NITSA_RS00600	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NITSA_RS00605	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NITSA_RS00610	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NITSA_RS00615	COG0200	Binds to the 23S rRNA
NITSA_RS00620	COG0201	protein transport
NITSA_RS00625	COG0024	Methionine aminopeptidase
NITSA_RS00630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NITSA_RS00635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NITSA_RS00640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NITSA_RS00645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NITSA_RS00650	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NITSA_RS00655	COG0202	RNA polymerase activity
NITSA_RS00660	COG0203	ribosomal protein L17
NITSA_RS00675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NITSA_RS00720	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NITSA_RS00725	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NITSA_RS00735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NITSA_RS00740	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NITSA_RS00755	COG1295	ribonuclease BN
NITSA_RS00765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NITSA_RS00770	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NITSA_RS00775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NITSA_RS00780	COG1355	regulation of microtubule-based process
NITSA_RS00790	COG2078	PFAM AMMECR1 domain protein
NITSA_RS00795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NITSA_RS00800	COG0135	phosphoribosylanthranilate isomerase activity
NITSA_RS00805	COG2176	DNA-directed DNA polymerase activity
NITSA_RS00815	COG0288	reversible hydration of carbon dioxide
NITSA_RS00820	COG0418	dihydroorotase activity
NITSA_RS00830	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NITSA_RS00835	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NITSA_RS00840	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NITSA_RS00845	COG0649	NAD binding
NITSA_RS00865	COG1034	ATP synthesis coupled electron transport
NITSA_RS00870	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NITSA_RS00875	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NITSA_RS00880	COG0839	Belongs to the complex I subunit 6 family
NITSA_RS00885	COG0713	ATP synthesis coupled electron transport
NITSA_RS00890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NITSA_RS00900	COG1007	ATP synthesis coupled electron transport
NITSA_RS00905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NITSA_RS00935	COG0194	GDP metabolic process
NITSA_RS00940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NITSA_RS00945	COG0018	arginyl-trna synthetase
NITSA_RS00955	COG2193	ferroxidase activity
NITSA_RS00960	COG1592	Rubrerythrin
NITSA_RS00965	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NITSA_RS00970	COG0799	negative regulation of ribosome biogenesis
NITSA_RS00975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NITSA_RS00980	COG0126	phosphoglycerate kinase activity
NITSA_RS00985	COG0149	triose-phosphate isomerase activity
NITSA_RS00990	COG0601	transmembrane transport
NITSA_RS01000	COG0195	Participates in both transcription termination and antitermination
NITSA_RS01010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NITSA_RS01015	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NITSA_RS01020	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NITSA_RS01025	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NITSA_RS01030	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NITSA_RS01035	COG0148	phosphopyruvate hydratase activity
NITSA_RS01045	COG0475	glutathione-regulated potassium exporter activity
NITSA_RS01045	COG0569	domain protein
NITSA_RS01050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NITSA_RS01060	COG0277	FAD linked oxidase domain protein
NITSA_RS01070	COG0739	heme binding
NITSA_RS01100	COG2957	Belongs to the agmatine deiminase family
NITSA_RS01105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NITSA_RS01165	COG0582	viral genome integration into host DNA
NITSA_RS01175	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NITSA_RS01180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NITSA_RS01190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NITSA_RS01195	COG0575	Belongs to the CDS family
NITSA_RS01200	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NITSA_RS01215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NITSA_RS01230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NITSA_RS01235	COG1053	succinate dehydrogenase
NITSA_RS01240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NITSA_RS01255	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NITSA_RS01260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NITSA_RS01265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NITSA_RS01265	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NITSA_RS01270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NITSA_RS01275	COG2022	thiamine diphosphate biosynthetic process
NITSA_RS01280	COG0159	tryptophan synthase activity
NITSA_RS01285	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NITSA_RS01290	COG2255	four-way junction helicase activity
NITSA_RS01295	COG0628	permease
NITSA_RS01300	COG0745	RESPONSE REGULATOR receiver
NITSA_RS01305	COG0642	Histidine kinase
NITSA_RS01315	COG1404	Belongs to the peptidase S8 family
NITSA_RS01335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NITSA_RS01340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NITSA_RS01350	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NITSA_RS01360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NITSA_RS01365	COG2321	neutral zinc metallopeptidase
NITSA_RS01370	COG5001	Diguanylate cyclase
NITSA_RS01375	COG0495	leucyl-tRNA aminoacylation
NITSA_RS01385	COG0285	dihydrofolate synthase activity
NITSA_RS01390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NITSA_RS01400	COG0714	Associated with various cellular activities
NITSA_RS01440	COG0287	Prephenate dehydrogenase
NITSA_RS01445	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NITSA_RS01450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NITSA_RS01455	COG0540	Belongs to the ATCase OTCase family
NITSA_RS01460	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NITSA_RS01465	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NITSA_RS01475	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NITSA_RS01480	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NITSA_RS01490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NITSA_RS01495	COG0193	aminoacyl-tRNA hydrolase activity
NITSA_RS01505	COG0019	diaminopimelate decarboxylase activity
NITSA_RS01510	COG1605	Chorismate mutase
NITSA_RS01510	COG0077	Prephenate dehydratase
NITSA_RS01515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NITSA_RS01525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NITSA_RS01530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NITSA_RS01535	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NITSA_RS01540	COG0105	UTP biosynthetic process
NITSA_RS01550	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NITSA_RS01555	COG0416	fatty acid biosynthetic process
NITSA_RS01560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NITSA_RS01580	COG1305	Transglutaminase-like
NITSA_RS01585	COG0709	Synthesizes selenophosphate from selenide and ATP
NITSA_RS01590	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NITSA_RS01600	COG1490	D-aminoacyl-tRNA deacylase activity
NITSA_RS01605	COG2326	polyphosphate kinase activity
NITSA_RS01610	COG0165	Argininosuccinate lyase
NITSA_RS01630	COG4932	domain protein
NITSA_RS01630	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
NITSA_RS01630	COG3266	domain, Protein
NITSA_RS01670	COG0537	adenosine 5'-monophosphoramidase activity
NITSA_RS01675	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NITSA_RS01680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NITSA_RS01680	COG0072	phenylalanine-tRNA ligase activity
NITSA_RS01685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NITSA_RS01690	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NITSA_RS01695	COG0539	negative regulation of cytoplasmic translation
NITSA_RS01695	COG1185	polyribonucleotide nucleotidyltransferase activity
NITSA_RS01700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NITSA_RS01710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NITSA_RS01720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NITSA_RS01725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NITSA_RS01730	COG0693	protein deglycase activity
NITSA_RS01735	COG0436	Aminotransferase
NITSA_RS01810	COG1393	Belongs to the ArsC family
NITSA_RS01815	COG0587	DNA-directed DNA polymerase activity
NITSA_RS01825	COG0039	L-malate dehydrogenase activity
NITSA_RS01835	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NITSA_RS01835	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NITSA_RS01840	COG0045	succinate-CoA ligase (ADP-forming) activity
NITSA_RS01845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NITSA_RS01850	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NITSA_RS01855	COG2010	Cytochrome c
NITSA_RS01875	COG3258	Cytochrome c
NITSA_RS01885	COG0737	Belongs to the 5'-nucleotidase family
NITSA_RS01900	COG0674	pyruvate-flavodoxin oxidoreductase activity
NITSA_RS01900	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NITSA_RS01905	COG1013	pyruvate-flavodoxin oxidoreductase activity
NITSA_RS01915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NITSA_RS01920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NITSA_RS01925	COG1466	dna polymerase III delta subunit
NITSA_RS01930	COG0557	exoribonuclease II activity
NITSA_RS01935	COG0501	Belongs to the peptidase M48B family
NITSA_RS01940	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NITSA_RS01945	COG2861	carbohydrate metabolic process
NITSA_RS01955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NITSA_RS01960	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NITSA_RS01965	COG0552	protein localization to endoplasmic reticulum
NITSA_RS01980	COG1418	mRNA catabolic process
NITSA_RS01995	COG0500	methyltransferase
NITSA_RS02000	COG0745	RESPONSE REGULATOR receiver
NITSA_RS02005	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NITSA_RS02005	COG2050	protein possibly involved in aromatic compounds catabolism
NITSA_RS02015	COG2833	Protein of unknown function (DUF455)
NITSA_RS02020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NITSA_RS02030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NITSA_RS02035	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NITSA_RS02045	COG0488	(ABC) transporter
NITSA_RS02050	COG0501	Belongs to the peptidase M48B family
NITSA_RS02055	COG2890	protein-(glutamine-N5) methyltransferase activity
NITSA_RS02070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NITSA_RS02075	COG2195	Cleaves the N-terminal amino acid of tripeptides
NITSA_RS02080	COG0745	RESPONSE REGULATOR receiver
NITSA_RS02095	COG2165	general secretion pathway protein
NITSA_RS02120	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NITSA_RS02125	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NITSA_RS02135	COG5002	protein histidine kinase activity
NITSA_RS02135	COG0784	Response regulator, receiver
NITSA_RS02135	COG2205	protein histidine kinase activity
NITSA_RS02150	COG0322	excinuclease ABC activity
NITSA_RS02160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NITSA_RS02170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NITSA_RS02170	COG0519	Catalyzes the synthesis of GMP from XMP
NITSA_RS02185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NITSA_RS02190	COG1722	exodeoxyribonuclease VII activity
NITSA_RS02200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NITSA_RS02210	COG0251	oxidation-reduction process
NITSA_RS02215	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NITSA_RS02220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NITSA_RS02225	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NITSA_RS02230	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NITSA_RS02235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NITSA_RS02240	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NITSA_RS02240	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NITSA_RS02245	COG1192	Involved in chromosome partitioning
NITSA_RS02250	COG1475	DNA binding
NITSA_RS02260	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NITSA_RS02265	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NITSA_RS02270	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NITSA_RS02275	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NITSA_RS02280	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NITSA_RS02285	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NITSA_RS02290	COG0811	peptide transport
NITSA_RS02295	COG0848	biopolymer transport protein
NITSA_RS02310	COG0326	Molecular chaperone. Has ATPase activity
NITSA_RS02340	COG0484	heat shock protein binding
NITSA_RS02345	COG1185	polyribonucleotide nucleotidyltransferase activity
NITSA_RS02355	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NITSA_RS02370	COG0484	heat shock protein binding
NITSA_RS02380	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NITSA_RS02390	COG2404	hydrolase activity, acting on ester bonds
NITSA_RS02400	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NITSA_RS02405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NITSA_RS02410	COG0443	Heat shock 70 kDa protein
NITSA_RS02420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NITSA_RS02435	COG0028	Belongs to the TPP enzyme family
NITSA_RS02440	COG0440	acetolactate synthase activity
NITSA_RS02455	COG0840	transmembrane signaling receptor activity
NITSA_RS02460	COG1410	methionine synthase
NITSA_RS02460	COG0646	methionine synthase
NITSA_RS02475	COG1597	lipid kinase activity
NITSA_RS02485	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NITSA_RS02490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NITSA_RS02495	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NITSA_RS02510	COG5002	protein histidine kinase activity
NITSA_RS02510	COG3850	Histidine kinase
NITSA_RS02515	COG0745	RESPONSE REGULATOR receiver
NITSA_RS02520	COG2205	protein histidine kinase activity
NITSA_RS02530	COG4263	nitrous-oxide reductase activity
NITSA_RS02545	COG0437	4 iron, 4 sulfur cluster binding
NITSA_RS02560	COG0348	domain, Protein
NITSA_RS02565	COG1131	(ABC) transporter
NITSA_RS02585	COG0840	transmembrane signaling receptor activity
NITSA_RS02590	COG0745	RESPONSE REGULATOR receiver
NITSA_RS02595	COG0811	peptide transport
NITSA_RS02600	COG0848	biopolymer transport protein
NITSA_RS02650	COG1136	(ABC) transporter
NITSA_RS02670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NITSA_RS02675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NITSA_RS02680	COG0825	malonyl-CoA metabolic process
NITSA_RS02685	COG0586	Pfam SNARE associated Golgi protein
NITSA_RS02690	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NITSA_RS02695	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NITSA_RS02700	COG4106	trans-aconitate 2-methyltransferase activity
NITSA_RS02710	COG2226	methyltransferase
NITSA_RS02715	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NITSA_RS02720	COG0642	Histidine kinase
NITSA_RS02725	COG0745	RESPONSE REGULATOR receiver
NITSA_RS02730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NITSA_RS02765	COG1136	(ABC) transporter
NITSA_RS02775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NITSA_RS02810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NITSA_RS02850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NITSA_RS02875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NITSA_RS02895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NITSA_RS02900	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NITSA_RS02905	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NITSA_RS02920	COG0512	Glutamine amidotransferase of anthranilate synthase
NITSA_RS02965	COG0140	phosphoribosyl-ATP diphosphatase activity
NITSA_RS02965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NITSA_RS02980	COG0840	transmembrane signaling receptor activity
NITSA_RS02985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NITSA_RS02995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NITSA_RS02995	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NITSA_RS03000	COG0788	formyltetrahydrofolate deformylase activity
NITSA_RS03005	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NITSA_RS03050	COG1294	oxidase, subunit
NITSA_RS03095	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NITSA_RS03105	COG0133	tryptophan synthase activity
NITSA_RS03115	COG0066	3-isopropylmalate dehydratase activity
NITSA_RS03120	COG0473	3-isopropylmalate dehydrogenase activity
NITSA_RS03130	COG0617	tRNA 3'-terminal CCA addition
NITSA_RS03140	COG0569	domain protein
NITSA_RS03145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NITSA_RS03150	COG1473	amidohydrolase
NITSA_RS03165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NITSA_RS03170	COG1121	(ABC) transporter
NITSA_RS03205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NITSA_RS03220	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NITSA_RS03225	COG0805	protein transport
NITSA_RS03235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NITSA_RS03240	COG0494	nUDIX hydrolase
NITSA_RS03245	COG0527	aspartate kinase activity
NITSA_RS03260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NITSA_RS03280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NITSA_RS03285	COG1132	(ABC) transporter
NITSA_RS03295	COG1160	GTP binding
NITSA_RS03300	COG0668	transmembrane transport
NITSA_RS03315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NITSA_RS03320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NITSA_RS03325	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NITSA_RS03330	COG0612	Peptidase, M16
NITSA_RS03335	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NITSA_RS03355	COG3383	formate dehydrogenase (NAD+) activity
NITSA_RS03360	COG0792	nuclease activity
NITSA_RS03375	COG3118	belongs to the thioredoxin family
NITSA_RS03380	COG0492	ferredoxin-NADP+ reductase activity
NITSA_RS03385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NITSA_RS03390	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NITSA_RS03395	COG1242	4 iron, 4 sulfur cluster binding
NITSA_RS03445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NITSA_RS03485	COG0405	Gamma-glutamyltransferase
NITSA_RS03490	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NITSA_RS03495	COG0174	glutamine synthetase
NITSA_RS03500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NITSA_RS03505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NITSA_RS03525	COG0826	peptidase U32
NITSA_RS03540	COG0752	glycyl-tRNA synthetase alpha subunit
NITSA_RS03545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NITSA_RS03555	COG1519	Transferase
NITSA_RS03560	COG1872	DUF167
NITSA_RS03565	COG0564	pseudouridine synthase activity
NITSA_RS03570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NITSA_RS03575	COG0356	it plays a direct role in the translocation of protons across the membrane
NITSA_RS03585	COG0352	thiamine-phosphate diphosphorylase activity
NITSA_RS03590	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NITSA_RS03595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NITSA_RS03605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NITSA_RS03640	COG0606	chelatase, subunit chli
NITSA_RS03650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NITSA_RS03655	COG1459	type II secretion system
NITSA_RS03660	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NITSA_RS03670	COG0484	heat shock protein binding
NITSA_RS03675	COG0789	Transcriptional regulator
NITSA_RS03680	COG1993	acr, cog1993
NITSA_RS03685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NITSA_RS03695	COG1981	membrane
NITSA_RS03705	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NITSA_RS03715	COG0668	transmembrane transport
NITSA_RS03765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NITSA_RS03770	COG0632	four-way junction helicase activity
NITSA_RS03780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NITSA_RS03815	COG0688	phosphatidylethanolamine metabolic process
NITSA_RS03825	COG0546	phosphoglycolate phosphatase activity
NITSA_RS03840	COG1704	LemA family
NITSA_RS03850	COG0280	phosphate acetyltransferase
NITSA_RS03850	COG0857	belongs to the CobB CobQ family
NITSA_RS03855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NITSA_RS03860	COG3093	addiction module antidote protein HigA
NITSA_RS03870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NITSA_RS03875	COG0742	ribosomal rna small subunit methyltransferase
NITSA_RS03895	COG0288	reversible hydration of carbon dioxide
NITSA_RS03900	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NITSA_RS03940	COG2801	Transposase and inactivated derivatives
NITSA_RS03985	COG0776	regulation of translation
NITSA_RS03990	COG1674	ftsk spoiiie
NITSA_RS03990	COG1196	nuclear chromosome segregation
NITSA_RS04000	COG1049	propionate catabolic process, 2-methylcitrate cycle
NITSA_RS04010	COG0387	Pfam Sodium calcium exchanger
NITSA_RS04030	COG1733	regulation of RNA biosynthetic process
NITSA_RS04035	COG1335	isochorismatase
NITSA_RS04050	COG0647	UMP catabolic process
NITSA_RS04055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NITSA_RS04060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NITSA_RS04065	COG0037	tRNA processing
NITSA_RS04090	COG0134	indole-3-glycerol-phosphate synthase activity
NITSA_RS04110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NITSA_RS04135	COG0697	spore germination
NITSA_RS04160	COG0683	leucine binding
NITSA_RS04170	COG1473	amidohydrolase
NITSA_RS04180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NITSA_RS04200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NITSA_RS04220	COG0714	Associated with various cellular activities
NITSA_RS04235	COG0457	Tetratricopeptide repeat
NITSA_RS04245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NITSA_RS04290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NITSA_RS04295	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NITSA_RS04310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NITSA_RS04325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NITSA_RS04345	COG0564	pseudouridine synthase activity
NITSA_RS04355	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NITSA_RS04360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NITSA_RS04375	COG0528	UMP kinase activity
NITSA_RS04380	COG1758	RNA polymerase activity
NITSA_RS04390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NITSA_RS04410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NITSA_RS04415	COG3174	membrane
NITSA_RS04425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NITSA_RS04430	COG0728	peptidoglycan biosynthetic process
NITSA_RS04465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NITSA_RS04470	COG4232	protein-disulfide reductase activity
NITSA_RS04475	COG1331	Highly conserved protein containing a thioredoxin domain
NITSA_RS04480	COG0101	tRNA pseudouridine synthase activity
NITSA_RS04490	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NITSA_RS04495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NITSA_RS04505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NITSA_RS04510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NITSA_RS04520	COG0585	pseudouridine synthase activity
NITSA_RS04525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NITSA_RS04530	COG0590	tRNA wobble adenosine to inosine editing
NITSA_RS04570	COG0142	geranyltranstransferase activity
NITSA_RS04575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NITSA_RS04580	COG0442	prolyl-tRNA aminoacylation
NITSA_RS04595	COG0181	hydroxymethylbilane synthase activity
NITSA_RS04600	COG0563	adenylate kinase activity
NITSA_RS04605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NITSA_RS04610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NITSA_RS04670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NITSA_RS04675	COG1028	Short-chain dehydrogenase reductase Sdr
NITSA_RS04680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NITSA_RS04685	COG0612	Peptidase, M16
NITSA_RS04720	COG1496	oxidoreductase activity
NITSA_RS04740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NITSA_RS04750	COG0488	(ABC) transporter
NITSA_RS04770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NITSA_RS04775	COG0084	hydrolase, TatD family'
NITSA_RS04785	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NITSA_RS04790	COG0131	Imidazoleglycerol-phosphate dehydratase
NITSA_RS04795	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NITSA_RS04825	COG0768	penicillin binding
NITSA_RS04830	COG0124	histidyl-tRNA synthetase
NITSA_RS04835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NITSA_RS04840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NITSA_RS04850	COG0163	prenyltransferase activity
NITSA_RS04860	COG3150	esterase
NITSA_RS04865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NITSA_RS04865	COG1796	DNA polymerase
NITSA_RS04875	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NITSA_RS04880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NITSA_RS04890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NITSA_RS04925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NITSA_RS04925	COG0574	Belongs to the PEP-utilizing enzyme family
NITSA_RS04940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NITSA_RS04950	COG3247	response to pH
NITSA_RS04955	COG0148	phosphopyruvate hydratase activity
NITSA_RS04960	COG0531	amino acid
NITSA_RS04980	COG2095	MarC family integral membrane protein
NITSA_RS04985	COG0586	Pfam SNARE associated Golgi protein
NITSA_RS05005	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NITSA_RS05015	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NITSA_RS05020	COG0297	glycogen (starch) synthase activity
NITSA_RS05035	COG1449	Belongs to the glycosyl hydrolase 57 family
NITSA_RS05045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NITSA_RS05055	COG0058	SHG alpha-glucan phosphorylase activity
NITSA_RS05060	COG0588	phosphoglycerate mutase activity
NITSA_RS05070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NITSA_RS05075	COG0022	dehydrogenase e1 component
NITSA_RS05080	COG0508	dehydrogenase complex catalyzes the overall conversion of
NITSA_RS05085	COG4716	Myosin-crossreactive antigen
NITSA_RS05090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NITSA_RS05125	COG0166	Belongs to the GPI family
NITSA_RS05135	COG0205	6-phosphofructokinase activity
NITSA_RS05140	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NITSA_RS05150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NITSA_RS05160	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NITSA_RS05165	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NITSA_RS05175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NITSA_RS05180	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NITSA_RS05200	COG0004	ammonium transporteR
NITSA_RS05210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NITSA_RS05220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NITSA_RS05225	COG0450	alkyl hydroperoxide reductase
NITSA_RS05235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NITSA_RS05245	COG1278	Cold shock
NITSA_RS05290	COG1166	arginine decarboxylase activity
NITSA_RS05295	COG1045	serine acetyltransferase
NITSA_RS05300	COG1489	DNA binding
NITSA_RS05320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NITSA_RS05320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NITSA_RS05355	COG1203	CRISPR-associated helicase, Cas3
NITSA_RS05360	COG2161	toxin-antitoxin pair type II binding
NITSA_RS05365	COG4115	mRNA cleavage
NITSA_RS05375	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NITSA_RS05405	COG0840	transmembrane signaling receptor activity
NITSA_RS05410	COG0745	RESPONSE REGULATOR receiver
NITSA_RS05420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NITSA_RS05430	COG3287	FIST C domain
NITSA_RS05430	COG2199	diguanylate cyclase activity
NITSA_RS05430	COG2200	EAL domain
NITSA_RS05435	COG0745	RESPONSE REGULATOR receiver
NITSA_RS05450	COG2048	Heterodisulfide reductase, subunit B
NITSA_RS05455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NITSA_RS05460	COG1053	succinate dehydrogenase
NITSA_RS05465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NITSA_RS05490	COG0133	tryptophan synthase activity
NITSA_RS05505	COG1309	transcriptional regulator
NITSA_RS05520	COG0210	DNA helicase
NITSA_RS05535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NITSA_RS05560	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NITSA_RS05570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NITSA_RS05575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NITSA_RS05610	COG1739	Uncharacterized protein family UPF0029
NITSA_RS05615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NITSA_RS05635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NITSA_RS05660	COG0729	surface antigen
NITSA_RS05665	COG4608	Belongs to the ABC transporter superfamily
NITSA_RS05670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NITSA_RS05695	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NITSA_RS05700	COG0681	Belongs to the peptidase S26 family
NITSA_RS05705	COG1994	Peptidase M50
NITSA_RS05710	COG0698	ribose 5-phosphate isomerase
NITSA_RS05720	COG0525	valine-tRNA ligase activity
NITSA_RS05735	COG2226	methyltransferase
NITSA_RS05760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NITSA_RS05765	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NITSA_RS05775	COG0497	DNA recombination
NITSA_RS05780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NITSA_RS05785	COG0708	Exodeoxyribonuclease III
NITSA_RS05790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NITSA_RS05795	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NITSA_RS05800	COG0137	argininosuccinate synthase activity
NITSA_RS05805	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NITSA_RS05815	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NITSA_RS05830	COG0653	protein targeting
NITSA_RS05845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NITSA_RS05855	COG0811	peptide transport
NITSA_RS05860	COG0848	biopolymer transport protein
NITSA_RS05865	COG0731	radical SAM domain protein
NITSA_RS06130	COG0582	viral genome integration into host DNA
NITSA_RS06135	COG0534	Mate efflux family protein
NITSA_RS06140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NITSA_RS06145	COG1127	ABC transporter
NITSA_RS06165	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NITSA_RS06170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NITSA_RS06175	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NITSA_RS06180	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NITSA_RS06185	COG1077	Cell shape determining protein MreB Mrl
NITSA_RS06195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NITSA_RS06205	COG0217	transcriptional regulatory protein
NITSA_RS06210	COG0585	pseudouridine synthase activity
NITSA_RS06245	COG0481	GTPase activity
NITSA_RS06260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NITSA_RS06265	COG5001	Diguanylate cyclase
NITSA_RS06265	COG3300	MHYT domain
NITSA_RS06270	COG0598	Magnesium transport protein CorA
NITSA_RS06280	COG1643	Atp-dependent helicase
NITSA_RS06305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NITSA_RS06315	COG0215	cysteine-tRNA ligase activity
NITSA_RS06320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NITSA_RS06325	COG1254	Belongs to the acylphosphatase family
NITSA_RS06345	COG1078	dGTPase activity
NITSA_RS06350	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NITSA_RS06360	COG0511	ligase activity, forming carbon-carbon bonds
NITSA_RS06375	COG1968	undecaprenyl-diphosphatase activity
NITSA_RS06380	COG1132	(ABC) transporter
NITSA_RS06385	COG0560	Phosphoserine phosphatase
NITSA_RS06395	COG0281	malic enzyme
NITSA_RS06400	COG0579	oxidoreductase
NITSA_RS06415	COG0372	Belongs to the citrate synthase family
NITSA_RS06425	COG0659	secondary active sulfate transmembrane transporter activity
NITSA_RS06470	COG0840	transmembrane signaling receptor activity
NITSA_RS06485	COG0521	Mo-molybdopterin cofactor biosynthetic process
NITSA_RS06490	COG0300	oxidoreductase activity
NITSA_RS06515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NITSA_RS06520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NITSA_RS06530	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NITSA_RS06540	COG0343	queuine tRNA-ribosyltransferase activity
NITSA_RS06545	COG1187	pseudouridine synthase activity
NITSA_RS06550	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NITSA_RS06600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NITSA_RS06610	COG0706	membrane insertase activity
NITSA_RS06620	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NITSA_RS06630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NITSA_RS06640	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NITSA_RS06645	COG2204	response regulator
NITSA_RS06655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NITSA_RS06660	COG1053	succinate dehydrogenase
NITSA_RS06670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NITSA_RS06690	COG3012	SEC-C Motif Domain Protein
NITSA_RS06700	COG2151	metal-sulfur cluster biosynthetic enzyme
NITSA_RS06710	COG0719	Fe-S assembly protein
NITSA_RS06715	COG0396	ATPase activity
NITSA_RS06720	COG0719	Fe-S assembly protein
NITSA_RS06730	COG0561	phosphatase activity
NITSA_RS06760	COG1794	racemase activity, acting on amino acids and derivatives
NITSA_RS06765	COG1028	Short-chain dehydrogenase reductase Sdr
NITSA_RS06790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NITSA_RS06790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NITSA_RS06810	COG0482	sulfurtransferase activity
NITSA_RS06820	COG1419	protein localization to endoplasmic reticulum
NITSA_RS06825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NITSA_RS06830	COG0006	proline dipeptidase activity
NITSA_RS06835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NITSA_RS06840	COG0402	S-adenosylhomocysteine deaminase activity
NITSA_RS06860	COG1333	cytochrome c biogenesis protein
NITSA_RS06860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NITSA_RS06895	COG0745	RESPONSE REGULATOR receiver
NITSA_RS06905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NITSA_RS06930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NITSA_RS06935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NITSA_RS06940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NITSA_RS06960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NITSA_RS06965	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NITSA_RS06980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NITSA_RS06990	COG0335	large ribosomal subunit rRNA binding
NITSA_RS06995	COG0336	Belongs to the RNA methyltransferase TrmD family
NITSA_RS07000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NITSA_RS07005	COG1837	Belongs to the UPF0109 family
NITSA_RS07010	COG0228	four-way junction DNA binding
NITSA_RS07020	COG1333	cytochrome c biogenesis protein
NITSA_RS07020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NITSA_RS07040	COG2824	Alkylphosphonate utilization operon protein PhnA
NITSA_RS07055	COG0438	transferase activity, transferring glycosyl groups
NITSA_RS07065	COG0463	Glycosyl transferase, family 2
NITSA_RS07100	COG2963	transposase activity
NITSA_RS07105	COG2801	Transposase and inactivated derivatives
NITSA_RS07120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NITSA_RS07145	COG1091	dTDP-4-dehydrorhamnose reductase activity
NITSA_RS07155	COG2244	polysaccharide biosynthetic process
NITSA_RS07165	COG0028	Belongs to the TPP enzyme family
NITSA_RS07165	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NITSA_RS07170	COG1454	alcohol dehydrogenase
NITSA_RS07195	COG0438	transferase activity, transferring glycosyl groups
NITSA_RS07200	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NITSA_RS07200	COG0662	Cupin 2, conserved barrel domain protein
NITSA_RS07215	COG0859	PFAM glycosyl transferase family 9
NITSA_RS07225	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NITSA_RS07230	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NITSA_RS07230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NITSA_RS07240	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NITSA_RS07245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NITSA_RS07270	COG0754	glutathionylspermidine amidase activity
NITSA_RS07285	COG0849	cell division
NITSA_RS07305	COG0275	rRNA processing
NITSA_RS07325	COG0167	dihydroorotate dehydrogenase activity
NITSA_RS07335	COG2354	Protein conserved in bacteria
NITSA_RS07350	COG0493	'glutamate synthase
NITSA_RS07355	COG0070	glutamate synthase
NITSA_RS07355	COG0069	glutamate synthase activity
NITSA_RS07355	COG0067	glutamate synthase
NITSA_RS07370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NITSA_RS07385	COG2081	HI0933 family
NITSA_RS07395	COG0750	zinc metalloprotease
NITSA_RS07400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NITSA_RS07410	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NITSA_RS07410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NITSA_RS07440	COG2226	methyltransferase
NITSA_RS07450	COG0586	Pfam SNARE associated Golgi protein
NITSA_RS07470	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NITSA_RS07480	COG0390	transport system, permease component
NITSA_RS07485	COG0352	thiamine-phosphate diphosphorylase activity
NITSA_RS07490	COG2020	methyltransferase activity
NITSA_RS07500	COG1331	Highly conserved protein containing a thioredoxin domain
NITSA_RS07505	COG2863	cytochrome
NITSA_RS07515	COG5002	protein histidine kinase activity
NITSA_RS07525	COG3118	belongs to the thioredoxin family
NITSA_RS07565	COG0681	Belongs to the peptidase S26 family
NITSA_RS07600	COG1573	uracil-dna glycosylase
NITSA_RS07605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NITSA_RS07605	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NITSA_RS07615	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NITSA_RS07620	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NITSA_RS07625	COG0359	binds to the 23S rRNA
NITSA_RS07635	COG0513	Belongs to the DEAD box helicase family
NITSA_RS07640	COG0542	response to heat
NITSA_RS07645	COG0793	Belongs to the peptidase S41A family
NITSA_RS07650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NITSA_RS07655	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NITSA_RS07660	COG0047	phosphoribosylformylglycinamidine synthase activity
NITSA_RS07670	COG0204	Acyl-transferase
NITSA_RS07690	COG2062	phosphohistidine phosphatase, SixA
NITSA_RS07695	COG0824	Thioesterase
NITSA_RS07705	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NITSA_RS07705	COG0316	Belongs to the HesB IscA family
NITSA_RS07725	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NITSA_RS07730	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NITSA_RS07740	COG0012	GTP binding
NITSA_RS07750	COG4807	Protein conserved in bacteria
NITSA_RS07755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NITSA_RS07760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NITSA_RS07780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NITSA_RS07785	COG0019	diaminopimelate decarboxylase activity
NITSA_RS07800	COG0514	ATP-dependent DNA helicase (RecQ)
NITSA_RS07830	COG1047	Peptidyl-prolyl cis-trans
NITSA_RS07840	COG0823	Involved in the tonB-independent uptake of proteins
NITSA_RS07845	COG0516	GMP reductase activity
NITSA_RS07845	COG0517	IMP dehydrogenase activity
NITSA_RS07850	COG0154	amidase activity
NITSA_RS07870	COG1028	Short-chain dehydrogenase reductase Sdr
NITSA_RS07875	COG2207	Transcriptional regulator
NITSA_RS07875	COG1917	Cupin 2, conserved barrel domain protein
NITSA_RS07885	COG2205	protein histidine kinase activity
NITSA_RS07905	COG3256	nitric oxide reductase
NITSA_RS07910	COG2010	Cytochrome c
NITSA_RS07935	COG0736	holo-[acyl-carrier-protein] synthase activity
NITSA_RS07940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NITSA_RS07945	COG0444	Belongs to the ABC transporter superfamily
NITSA_RS07950	COG0156	8-amino-7-oxononanoate synthase activity
NITSA_RS07955	COG0424	maF-like protein
NITSA_RS07960	COG1276	copper resistance
NITSA_RS07965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NITSA_RS07980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NITSA_RS07985	COG0772	Belongs to the SEDS family
NITSA_RS07995	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NITSA_RS08000	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NITSA_RS08010	COG1136	(ABC) transporter
NITSA_RS08015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NITSA_RS08020	COG0052	Belongs to the universal ribosomal protein uS2 family
NITSA_RS08030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NITSA_RS08060	COG1012	belongs to the aldehyde dehydrogenase family
NITSA_RS08075	COG2151	metal-sulfur cluster biosynthetic enzyme
NITSA_RS08090	COG1648	precorrin-2 dehydrogenase activity
NITSA_RS08090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NITSA_RS08115	COG3043	anaerobic respiration
NITSA_RS08120	COG0348	domain, Protein
NITSA_RS08125	COG0437	4 iron, 4 sulfur cluster binding
NITSA_RS08130	COG0243	molybdopterin cofactor binding
NITSA_RS08135	COG1522	sequence-specific DNA binding
NITSA_RS08140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NITSA_RS08145	COG1587	Uroporphyrinogen-III synthase
NITSA_RS08145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NITSA_RS08150	COG0535	radical SAM domain protein
NITSA_RS08165	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NITSA_RS08170	COG2995	paraquat-inducible protein a
NITSA_RS08175	COG2995	paraquat-inducible protein a
NITSA_RS08180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NITSA_RS08180	COG3008	intermembrane lipid transfer
NITSA_RS08190	COG3706	GGDEF domain
NITSA_RS08195	COG2205	protein histidine kinase activity
NITSA_RS08195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NITSA_RS08200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NITSA_RS08210	COG2022	thiamine diphosphate biosynthetic process
NITSA_RS08210	COG2104	thiamine diphosphate biosynthetic process
NITSA_RS08235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NITSA_RS08240	COG0038	chloride channel
NITSA_RS08245	COG0196	riboflavin kinase activity
NITSA_RS08255	COG1671	Belongs to the UPF0178 family
NITSA_RS08260	COG1280	lysine exporter protein (LysE YggA)
NITSA_RS08275	COG2204	response regulator
NITSA_RS08295	COG1301	dicarboxylic acid transport
NITSA_RS08300	COG1332	CRISPR-associated RAMP protein, Csm5 family
NITSA_RS08305	COG1851	Uncharacterised protein family (UPF0128)
NITSA_RS08315	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NITSA_RS08325	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NITSA_RS08335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NITSA_RS08345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NITSA_RS08365	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NITSA_RS08370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NITSA_RS08385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NITSA_RS08395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NITSA_RS08410	COG0489	protein tyrosine kinase activity
NITSA_RS08415	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NITSA_RS08420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NITSA_RS08420	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NITSA_RS08430	COG2046	Belongs to the sulfate adenylyltransferase family
NITSA_RS08435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NITSA_RS08455	COG1704	LemA family
NITSA_RS08490	COG2217	Heavy metal translocating P-type atpase
NITSA_RS08545	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NITSA_RS08550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NITSA_RS08555	COG2264	protein methyltransferase activity
NITSA_RS08560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NITSA_RS08565	COG1183	phosphatidylcholine synthase activity
NITSA_RS08570	COG1970	mechanosensitive ion channel activity
NITSA_RS08580	COG1854	S-ribosylhomocysteine lyase activity
NITSA_RS08585	COG1570	exodeoxyribonuclease VII activity
NITSA_RS08595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NITSA_RS08595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NITSA_RS08605	COG1881	PFAM PEBP family protein
NITSA_RS08610	COG0697	spore germination
NITSA_RS08615	COG0179	Fumarylacetoacetate (FAA) hydrolase
NITSA_RS08620	COG2252	PERMEase
NITSA_RS08630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NITSA_RS08635	COG4597	amino acid ABC transporter
NITSA_RS08640	COG0765	amino acid transport
NITSA_RS08645	COG1126	abc transporter atp-binding protein
NITSA_RS08650	COG2860	membrane
NITSA_RS08710	COG0438	transferase activity, transferring glycosyl groups
NITSA_RS08715	COG0297	glycogen (starch) synthase activity
NITSA_RS08770	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NITSA_RS08790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NITSA_RS08820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NITSA_RS08820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NITSA_RS08845	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NITSA_RS08850	COG1013	pyruvate-flavodoxin oxidoreductase activity
NITSA_RS08855	COG0674	pyruvate-flavodoxin oxidoreductase activity
NITSA_RS08860	COG1144	Oxidoreductase
NITSA_RS08865	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NITSA_RS08870	COG0546	phosphoglycolate phosphatase activity
NITSA_RS08880	COG0446	pyridine nucleotide-disulphide oxidoreductase
NITSA_RS08885	COG0242	peptide deformylase activity
NITSA_RS08890	COG0243	molybdopterin cofactor binding
NITSA_RS08895	COG0437	4 iron, 4 sulfur cluster binding
NITSA_RS08910	COG0582	viral genome integration into host DNA
NITSA_RS09165	COG0629	single-stranded DNA binding
NITSA_RS09170	COG0863	Belongs to the N(4) N(6)-methyltransferase family
NITSA_RS09225	COG1921	L-seryl-tRNASec selenium transferase activity
NITSA_RS09235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NITSA_RS09235	COG0425	Belongs to the sulfur carrier protein TusA family
NITSA_RS09255	COG0489	protein tyrosine kinase activity
NITSA_RS09270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NITSA_RS09275	COG1116	anion transmembrane transporter activity
NITSA_RS09295	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NITSA_RS09320	COG0651	ATP synthesis coupled electron transport
NITSA_RS09325	COG1666	GTP binding
NITSA_RS09330	COG0460	homoserine dehydrogenase
NITSA_RS09335	COG0436	Aminotransferase
NITSA_RS09345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NITSA_RS09355	COG0254	rRNA binding
NITSA_RS09370	COG2863	cytochrome
NITSA_RS09375	COG0602	queuosine metabolic process
NITSA_RS09380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NITSA_RS09385	COG2857	Cytochrome c1
NITSA_RS09390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NITSA_RS09395	COG0723	plastoquinol--plastocyanin reductase activity
NITSA_RS09405	COG0445	tRNA wobble uridine modification
NITSA_RS09410	COG0307	riboflavin synthase, alpha
NITSA_RS09445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NITSA_RS09450	COG0360	Binds together with S18 to 16S ribosomal RNA
NITSA_RS09455	COG0629	single-stranded DNA binding
NITSA_RS09460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NITSA_RS09465	COG1137	ATPase activity
NITSA_RS09470	COG0802	atpase or kinase
NITSA_RS09475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NITSA_RS09480	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NITSA_RS09490	COG2171	N-acyltransferase activity
NITSA_RS09505	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NITSA_RS09510	COG0243	molybdopterin cofactor binding
NITSA_RS09520	COG0284	orotidine-5'-phosphate decarboxylase activity
NITSA_RS09525	COG0303	'Molybdopterin
NITSA_RS09535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NITSA_RS09540	COG0459	protein refolding
NITSA_RS09545	COG0584	glycerophosphoryl diester phosphodiesterase
NITSA_RS09550	COG0779	Required for maturation of 30S ribosomal subunits
NITSA_RS09560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NITSA_RS09565	COG0083	homoserine kinase activity
NITSA_RS09575	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NITSA_RS09580	COG4942	peptidase
NITSA_RS09585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NITSA_RS09590	COG0157	Belongs to the NadC ModD family
NITSA_RS09600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NITSA_RS09615	COG0745	RESPONSE REGULATOR receiver
NITSA_RS09625	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NITSA_RS09630	COG0248	Ppx GppA phosphatase
NITSA_RS09635	COG0469	pyruvate kinase activity
NITSA_RS09640	COG0705	Rhomboid family
NITSA_RS09655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NITSA_RS09660	COG0357	Ribosomal RNA small subunit methyltransferase G
NITSA_RS09665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NITSA_RS09670	COG0113	porphobilinogen synthase activity
NITSA_RS09675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NITSA_RS09680	COG3706	GGDEF domain
NITSA_RS09700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NITSA_RS09705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NITSA_RS09710	COG1074	ATP-dependent DNA helicase activity
NITSA_RS09750	COG3278	Belongs to the heme-copper respiratory oxidase family
NITSA_RS09755	COG1181	Belongs to the D-alanine--D-alanine ligase family
NITSA_RS09770	COG0505	Belongs to the CarA family
NITSA_RS09780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NITSA_RS09785	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NITSA_RS09790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NITSA_RS09805	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NITSA_RS09810	COG2814	Major facilitator Superfamily
NITSA_RS09815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NITSA_RS09825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NITSA_RS09830	COG4221	oxidoreductase activity
NITSA_RS09845	COG0038	chloride channel
NITSA_RS09855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NITSA_RS09860	COG0049	tRNA binding
NITSA_RS09865	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NITSA_RS09870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NITSA_RS09875	COG0085	RNA polymerase activity
NITSA_RS09880	COG0222	ribosome binding
NITSA_RS09885	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NITSA_RS09890	COG0081	regulation of translation
NITSA_RS09895	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NITSA_RS09900	COG0250	Participates in transcription elongation, termination and antitermination
NITSA_RS09915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NITSA_RS09940	COG3022	response to hydroperoxide
NITSA_RS09975	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NITSA_RS09985	COG0187	DNA topoisomerase II activity
NITSA_RS09990	COG0303	'Molybdopterin
NITSA_RS09995	COG0314	molybdopterin synthase activity
NITSA_RS10005	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NITSA_RS10010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NITSA_RS10015	COG1086	Polysaccharide biosynthesis protein
NITSA_RS10020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NITSA_RS10060	COG1132	(ABC) transporter
NITSA_RS10075	COG0439	Biotin carboxylase
NITSA_RS10080	COG0511	ligase activity, forming carbon-carbon bonds
NITSA_RS10085	COG0717	Belongs to the dCTP deaminase family
NITSA_RS10090	COG4974	Belongs to the 'phage' integrase family
NITSA_RS10105	COG1193	negative regulation of DNA recombination
NITSA_RS10120	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NITSA_RS10125	COG2027	D-alanyl-D-alanine carboxypeptidase
NITSA_RS10130	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NITSA_RS10135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NITSA_RS10140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NITSA_RS10145	COG1862	Preprotein translocase
NITSA_RS10150	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NITSA_RS10155	COG0318	PFAM AMP-dependent synthetase and ligase
NITSA_RS10170	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NITSA_RS10190	COG0071	Belongs to the small heat shock protein (HSP20) family
NITSA_RS10205	COG0658	competence protein
NITSA_RS10205	COG2333	competence protein COMEC
NITSA_RS10210	COG0305	Participates in initiation and elongation during chromosome replication
NITSA_RS10215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NITSA_RS10220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NITSA_RS10230	COG2165	general secretion pathway protein
NITSA_RS10245	COG0028	Belongs to the TPP enzyme family
NITSA_RS10260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NITSA_RS10275	COG0463	Glycosyl transferase, family 2
NITSA_RS10320	COG0556	nucleotide-excision repair
NITSA_RS10325	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NITSA_RS10330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NITSA_RS10350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NITSA_RS10360	COG0037	tRNA processing
NITSA_RS10380	COG2841	Protein conserved in bacteria
NITSA_RS10405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NITSA_RS10410	COG0306	phosphate transporter
NITSA_RS10420	COG2205	protein histidine kinase activity
NITSA_RS10430	COG2951	lytic endotransglycosylase activity
NITSA_RS10435	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NITSA_RS10440	COG0571	ribonuclease III activity
NITSA_RS10445	COG0328	RNA-DNA hybrid ribonuclease activity
NITSA_RS10455	COG0358	DNA primase activity
NITSA_RS10460	COG0137	argininosuccinate synthase activity
NITSA_RS10480	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NITSA_RS10485	COG1252	NADH dehydrogenase
NITSA_RS10490	COG0348	domain, Protein
NITSA_RS10500	COG0315	cyclic pyranopterin monophosphate synthase activity
NITSA_RS10510	COG2995	paraquat-inducible protein a
NITSA_RS10520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NITSA_RS10530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NITSA_RS10535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NITSA_RS10540	COG0268	Binds directly to 16S ribosomal RNA
NITSA_RS10545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NITSA_RS10555	COG2814	Major facilitator Superfamily
NITSA_RS10580	COG1129	ABC transporter
NITSA_RS10580	COG0842	Transport permease protein
NITSA_RS10585	COG0842	Transport permease protein
NITSA_RS10590	COG0842	Transport permease protein
NITSA_RS10595	COG0671	phosphoesterase, PA-phosphatase related
NITSA_RS10635	COG0670	Belongs to the BI1 family
NITSA_RS10640	COG0352	thiamine-phosphate diphosphorylase activity
NITSA_RS10650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NITSA_RS10655	COG0233	cytoplasmic translational termination
NITSA_RS10660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NITSA_RS10665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NITSA_RS10670	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NITSA_RS10690	COG2081	HI0933 family
NITSA_RS10695	COG1217	gtp-binding protein TYPA
NITSA_RS10700	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NITSA_RS10705	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
NITSA_RS10710	COG2989	Protein conserved in bacteria
NITSA_RS10715	COG0492	ferredoxin-NADP+ reductase activity
NITSA_RS10720	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NITSA_RS10755	COG1388	LysM domain
NITSA_RS10755	COG3584	3D domain protein
NITSA_RS10765	COG1309	transcriptional regulator
NITSA_RS10770	COG1058	Belongs to the CinA family
NITSA_RS10770	COG1546	Belongs to the CinA family
NITSA_RS10775	COG0791	NLP P60 protein
NITSA_RS10775	COG3883	PFAM NLP P60 protein
NITSA_RS10780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NITSA_RS10815	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NITSA_RS10825	COG0772	Belongs to the SEDS family
NITSA_RS10855	COG5002	protein histidine kinase activity
NITSA_RS10935	COG2885	chlorophyll binding
NITSA_RS10940	COG2205	protein histidine kinase activity
NITSA_RS10945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NITSA_RS10995	COG1309	transcriptional regulator