locus-tag	class	description
JG735_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JG735_RS00010	COG0592	DNA-directed DNA polymerase activity
JG735_RS00015	COG0187	DNA topoisomerase II activity
JG735_RS00020	COG5001	Diguanylate cyclase
JG735_RS00020	COG5002	protein histidine kinase activity
JG735_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JG735_RS00030	COG1053	succinate dehydrogenase
JG735_RS00070	COG0450	alkyl hydroperoxide reductase
JG735_RS00080	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JG735_RS00085	COG4149	molybdate abc transporter
JG735_RS00120	COG3746	phosphate-selective porin O and P
JG735_RS00125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JG735_RS00140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JG735_RS00150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JG735_RS00185	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JG735_RS00195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JG735_RS00205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JG735_RS00220	COG0300	oxidoreductase activity
JG735_RS00225	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG735_RS00230	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JG735_RS00235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JG735_RS00240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JG735_RS00245	COG0564	pseudouridine synthase activity
JG735_RS00250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JG735_RS00255	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JG735_RS00265	COG0107	imidazoleglycerol-phosphate synthase activity
JG735_RS00270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JG735_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JG735_RS00280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JG735_RS00285	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JG735_RS00285	COG0517	IMP dehydrogenase activity
JG735_RS00290	COG1187	pseudouridine synthase activity
JG735_RS00295	COG0432	Pfam Uncharacterised protein family UPF0047
JG735_RS00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JG735_RS00300	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JG735_RS00320	COG1490	D-aminoacyl-tRNA deacylase activity
JG735_RS00330	COG3177	Filamentation induced by cAMP protein fic
JG735_RS00365	COG2095	MarC family integral membrane protein
JG735_RS00370	COG1309	transcriptional regulator
JG735_RS00395	COG4232	protein-disulfide reductase activity
JG735_RS00410	COG0633	Ferredoxin
JG735_RS00410	COG0543	2 iron, 2 sulfur cluster binding
JG735_RS00445	COG0730	response to heat
JG735_RS00460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JG735_RS00505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JG735_RS00520	COG0237	dephospho-CoA kinase activity
JG735_RS00525	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JG735_RS00535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JG735_RS00540	COG0268	Binds directly to 16S ribosomal RNA
JG735_RS00545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JG735_RS00550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JG735_RS00565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JG735_RS00570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JG735_RS00575	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JG735_RS00585	COG2203	Gaf domain
JG735_RS00585	COG3706	GGDEF domain
JG735_RS00585	COG5001	Diguanylate cyclase
JG735_RS00585	COG4251	negative regulation of phosphorylation
JG735_RS00610	COG1162	GTPase activity
JG735_RS00615	COG0129	dihydroxy-acid dehydratase activity
JG735_RS00655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JG735_RS00665	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JG735_RS00675	COG2226	methyltransferase
JG735_RS00680	COG2226	methyltransferase
JG735_RS00695	COG5001	Diguanylate cyclase
JG735_RS00700	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JG735_RS00715	COG0667	Aldo Keto reductase
JG735_RS00725	COG0348	domain, Protein
JG735_RS00750	COG1271	oxidase subunit
JG735_RS00755	COG1294	oxidase, subunit
JG735_RS00760	COG2200	EAL domain
JG735_RS00760	COG3287	FIST C domain
JG735_RS00760	COG2199	diguanylate cyclase activity
JG735_RS00790	COG0504	CTP synthase activity
JG735_RS00795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JG735_RS00830	COG0544	peptidyl-prolyl cis-trans isomerase activity
JG735_RS00835	COG0740	serine-type endopeptidase activity
JG735_RS00840	COG0242	peptide deformylase activity
JG735_RS00845	COG0606	chelatase, subunit chli
JG735_RS00910	COG2855	membrane
JG735_RS00915	COG0583	DNA-binding transcription factor activity
JG735_RS00920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JG735_RS00920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JG735_RS00930	COG3174	membrane
JG735_RS00935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JG735_RS00940	COG2022	thiamine diphosphate biosynthetic process
JG735_RS00950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG735_RS00955	COG0733	neurotransmitter:sodium symporter activity
JG735_RS01010	COG3787	Belongs to the UPF0306 family
JG735_RS01020	COG1981	membrane
JG735_RS01030	COG1194	a g-specific adenine glycosylase
JG735_RS01035	COG3228	Belongs to the MtfA family
JG735_RS01050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JG735_RS01055	COG0482	sulfurtransferase activity
JG735_RS01060	COG0358	DNA primase activity
JG735_RS01070	COG0328	RNA-DNA hybrid ribonuclease activity
JG735_RS01075	COG0571	ribonuclease III activity
JG735_RS01080	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JG735_RS01095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JG735_RS01155	COG2003	Belongs to the UPF0758 family
JG735_RS01165	COG0051	transcription antitermination factor activity, RNA binding
JG735_RS01170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JG735_RS01175	COG0088	Forms part of the polypeptide exit tunnel
JG735_RS01180	COG0089	rRNA binding
JG735_RS01185	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JG735_RS01190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JG735_RS01195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JG735_RS01200	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JG735_RS01205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JG735_RS01210	COG0255	Belongs to the universal ribosomal protein uL29 family
JG735_RS01215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JG735_RS01220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JG735_RS01225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JG735_RS01230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JG735_RS01235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JG735_RS01240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JG735_RS01245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JG735_RS01250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JG735_RS01255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JG735_RS01260	COG0200	Binds to the 23S rRNA
JG735_RS01265	COG0201	protein transport
JG735_RS01270	COG0024	Methionine aminopeptidase
JG735_RS01275	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JG735_RS01280	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JG735_RS01285	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JG735_RS01290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JG735_RS01295	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JG735_RS01300	COG0202	RNA polymerase activity
JG735_RS01305	COG0203	ribosomal protein L17
JG735_RS01320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JG735_RS01330	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JG735_RS01335	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JG735_RS01345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JG735_RS01370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JG735_RS01375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JG735_RS01390	COG0250	Participates in transcription elongation, termination and antitermination
JG735_RS01395	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JG735_RS01400	COG0081	regulation of translation
JG735_RS01405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JG735_RS01410	COG0222	ribosome binding
JG735_RS01415	COG0085	RNA polymerase activity
JG735_RS01420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JG735_RS01425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JG735_RS01430	COG0049	tRNA binding
JG735_RS01435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JG735_RS01450	COG2201	protein-glutamate methylesterase activity
JG735_RS01460	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JG735_RS01475	COG0724	RNA recognition motif
JG735_RS01480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JG735_RS01490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JG735_RS01500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JG735_RS01515	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JG735_RS01525	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JG735_RS01530	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JG735_RS01535	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JG735_RS01540	COG0649	NAD binding
JG735_RS01565	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JG735_RS01570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JG735_RS01575	COG0839	Belongs to the complex I subunit 6 family
JG735_RS01580	COG0713	ATP synthesis coupled electron transport
JG735_RS01585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JG735_RS01595	COG1007	ATP synthesis coupled electron transport
JG735_RS01600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JG735_RS01620	COG0582	viral genome integration into host DNA
JG735_RS01725	COG0629	single-stranded DNA binding
JG735_RS01825	COG1783	phage Terminase large subunit
JG735_RS01870	COG0459	protein refolding
JG735_RS01940	COG5001	Diguanylate cyclase
JG735_RS01940	COG4251	negative regulation of phosphorylation
JG735_RS01940	COG3706	GGDEF domain
JG735_RS01940	COG2203	Gaf domain
JG735_RS01960	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JG735_RS01965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JG735_RS01975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JG735_RS01980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JG735_RS01985	COG0825	malonyl-CoA metabolic process
JG735_RS02000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JG735_RS02005	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JG735_RS02010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JG735_RS02015	COG0135	phosphoribosylanthranilate isomerase activity
JG735_RS02020	COG2176	DNA-directed DNA polymerase activity
JG735_RS02025	COG1301	dicarboxylic acid transport
JG735_RS02030	COG0242	peptide deformylase activity
JG735_RS02045	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JG735_RS02050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JG735_RS02055	COG0288	reversible hydration of carbon dioxide
JG735_RS02060	COG0556	nucleotide-excision repair
JG735_RS02075	COG2165	general secretion pathway protein
JG735_RS02080	COG2165	general secretion pathway protein
JG735_RS02090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JG735_RS02095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JG735_RS02100	COG0305	Participates in initiation and elongation during chromosome replication
JG735_RS02110	COG1295	ribonuclease BN
JG735_RS02115	COG0277	FAD linked oxidase domain protein
JG735_RS02125	COG0739	heme binding
JG735_RS02130	COG2239	Acts as a magnesium transporter
JG735_RS02150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JG735_RS02155	COG1121	(ABC) transporter
JG735_RS02160	COG0803	Belongs to the bacterial solute-binding protein 9 family
JG735_RS02175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JG735_RS02190	COG0357	Ribosomal RNA small subunit methyltransferase G
JG735_RS02195	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JG735_RS02200	COG0113	porphobilinogen synthase activity
JG735_RS02205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JG735_RS02220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JG735_RS02230	COG1074	ATP-dependent DNA helicase activity
JG735_RS02235	COG0247	lactate metabolic process
JG735_RS02245	COG0840	transmembrane signaling receptor activity
JG735_RS02245	COG3290	protein histidine kinase activity
JG735_RS02250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JG735_RS02255	COG0628	permease
JG735_RS02260	COG2255	four-way junction helicase activity
JG735_RS02265	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JG735_RS02270	COG0159	tryptophan synthase activity
JG735_RS02310	COG0540	Belongs to the ATCase OTCase family
JG735_RS02320	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JG735_RS02325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JG735_RS02335	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JG735_RS02350	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JG735_RS02355	COG0193	aminoacyl-tRNA hydrolase activity
JG735_RS02365	COG0019	diaminopimelate decarboxylase activity
JG735_RS02375	COG1605	Chorismate mutase
JG735_RS02375	COG0077	Prephenate dehydratase
JG735_RS02380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JG735_RS02385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JG735_RS02390	COG0450	alkyl hydroperoxide reductase
JG735_RS02395	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JG735_RS02400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JG735_RS02405	COG0105	UTP biosynthetic process
JG735_RS02415	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JG735_RS02420	COG0416	fatty acid biosynthetic process
JG735_RS02425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JG735_RS02455	COG0714	Associated with various cellular activities
JG735_RS02485	COG0287	Prephenate dehydrogenase
JG735_RS02490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JG735_RS02495	COG1077	Cell shape determining protein MreB Mrl
JG735_RS02500	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JG735_RS02505	COG0642	Histidine kinase
JG735_RS02510	COG0745	RESPONSE REGULATOR receiver
JG735_RS02520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JG735_RS02530	COG0157	Belongs to the NadC ModD family
JG735_RS02545	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JG735_RS02555	COG0083	homoserine kinase activity
JG735_RS02565	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JG735_RS02570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JG735_RS02575	COG0779	Required for maturation of 30S ribosomal subunits
JG735_RS02580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JG735_RS02580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JG735_RS02590	COG5001	Diguanylate cyclase
JG735_RS02590	COG3300	MHYT domain
JG735_RS02595	COG1570	exodeoxyribonuclease VII activity
JG735_RS02605	COG0616	signal peptide processing
JG735_RS02610	COG0402	S-adenosylhomocysteine deaminase activity
JG735_RS02615	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JG735_RS02620	COG0006	proline dipeptidase activity
JG735_RS02625	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JG735_RS02630	COG0455	bacterial-type flagellum organization
JG735_RS02635	COG0482	sulfurtransferase activity
JG735_RS02640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JG735_RS02645	COG0481	GTPase activity
JG735_RS02670	COG0731	radical SAM domain protein
JG735_RS02675	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JG735_RS02685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JG735_RS02710	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JG735_RS02715	COG0243	molybdopterin cofactor binding
JG735_RS02720	COG0437	4 iron, 4 sulfur cluster binding
JG735_RS02725	COG0515	serine threonine protein kinase
JG735_RS02725	COG2815	serine threonine protein kinase
JG735_RS02730	COG2223	nitrite transmembrane transporter activity
JG735_RS02735	COG0004	ammonium transporteR
JG735_RS02765	COG0019	diaminopimelate decarboxylase activity
JG735_RS02770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JG735_RS02780	COG1730	sister chromatid segregation
JG735_RS02805	COG2132	Multicopper oxidase
JG735_RS02825	COG0459	protein refolding
JG735_RS02840	COG0745	RESPONSE REGULATOR receiver
JG735_RS02875	COG0284	orotidine-5'-phosphate decarboxylase activity
JG735_RS02880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JG735_RS02910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JG735_RS02935	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JG735_RS02955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JG735_RS02960	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JG735_RS02960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JG735_RS02965	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JG735_RS02970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JG735_RS02975	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JG735_RS02980	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JG735_RS02985	COG1077	Cell shape determining protein MreB Mrl
JG735_RS02995	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JG735_RS03005	COG1858	cytochrome C peroxidase
JG735_RS03015	COG0840	transmembrane signaling receptor activity
JG735_RS03020	COG0646	methionine synthase
JG735_RS03020	COG1410	methionine synthase
JG735_RS03040	COG4206	TonB-dependent receptor
JG735_RS03060	COG2195	Cleaves the N-terminal amino acid of tripeptides
JG735_RS03070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JG735_RS03075	COG0217	transcriptional regulatory protein
JG735_RS03080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JG735_RS03085	COG0191	fructose-bisphosphate aldolase activity
JG735_RS03100	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JG735_RS03105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JG735_RS03110	COG0306	phosphate transporter
JG735_RS03120	COG2199	diguanylate cyclase activity
JG735_RS03120	COG3287	FIST C domain
JG735_RS03120	COG2200	EAL domain
JG735_RS03170	COG0704	Plays a role in the regulation of phosphate uptake
JG735_RS03175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JG735_RS03185	COG0573	inorganic phosphate transmembrane transporter activity
JG735_RS03195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JG735_RS03215	COG0714	Associated with various cellular activities
JG735_RS03225	COG2304	oxidoreductase activity
JG735_RS03240	COG2046	Belongs to the sulfate adenylyltransferase family
JG735_RS03245	COG0745	RESPONSE REGULATOR receiver
JG735_RS03250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JG735_RS03250	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JG735_RS03255	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JG735_RS03260	COG0489	protein tyrosine kinase activity
JG735_RS03270	COG0840	transmembrane signaling receptor activity
JG735_RS03285	COG0784	Response regulator, receiver
JG735_RS03285	COG0835	chemotaxis
JG735_RS03290	COG0835	chemotaxis
JG735_RS03295	COG2198	Histidine kinase
JG735_RS03295	COG0643	Histidine kinase
JG735_RS03305	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JG735_RS03320	COG4786	Flagellar basal body rod
JG735_RS03335	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JG735_RS03340	COG1706	bacterial-type flagellum-dependent cell motility
JG735_RS03350	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JG735_RS03355	COG1419	protein localization to endoplasmic reticulum
JG735_RS03360	COG0455	bacterial-type flagellum organization
JG735_RS03365	COG1191	sigma factor activity
JG735_RS03380	COG1815	bacterial-type flagellum-dependent cell motility
JG735_RS03385	COG1558	bacterial-type flagellum-dependent cell motility
JG735_RS03390	COG1677	Flagellar hook-basal body complex protein FliE
JG735_RS03395	COG1766	The M ring may be actively involved in energy transduction
JG735_RS03405	COG1157	protein secretion by the type III secretion system
JG735_RS03420	COG1580	Controls the rotational direction of flagella during chemotaxis
JG735_RS03435	COG1338	Plays a role in the flagellum-specific transport system
JG735_RS03440	COG1987	bacterial-type flagellum assembly
JG735_RS03445	COG1684	flagellar biosynthetic protein fliR
JG735_RS03450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JG735_RS03470	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JG735_RS03475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JG735_RS03490	COG1516	flagellar protein fliS
JG735_RS03505	COG1256	bacterial-type flagellum assembly
JG735_RS03515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JG735_RS03520	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JG735_RS03525	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JG735_RS03540	COG0045	succinate-CoA ligase (ADP-forming) activity
JG735_RS03585	COG0165	Argininosuccinate lyase
JG735_RS03590	COG0537	adenosine 5'-monophosphoramidase activity
JG735_RS03595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JG735_RS03600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JG735_RS03600	COG0072	phenylalanine-tRNA ligase activity
JG735_RS03605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JG735_RS03610	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JG735_RS03615	COG0539	negative regulation of cytoplasmic translation
JG735_RS03615	COG1185	polyribonucleotide nucleotidyltransferase activity
JG735_RS03620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JG735_RS03630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JG735_RS03635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JG735_RS03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JG735_RS03650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JG735_RS03660	COG0693	protein deglycase activity
JG735_RS03670	COG1216	Glycosyl transferase, family 2
JG735_RS03675	COG0561	phosphatase activity
JG735_RS03680	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JG735_RS03680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JG735_RS03685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JG735_RS03690	COG0587	DNA-directed DNA polymerase activity
JG735_RS03715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JG735_RS03715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JG735_RS03720	COG3300	MHYT domain
JG735_RS03720	COG5001	Diguanylate cyclase
JG735_RS03725	COG0824	Thioesterase
JG735_RS03735	COG1573	uracil-dna glycosylase
JG735_RS03750	COG2048	Heterodisulfide reductase, subunit B
JG735_RS03760	COG1053	succinate dehydrogenase
JG735_RS03770	COG0585	pseudouridine synthase activity
JG735_RS03780	COG3706	GGDEF domain
JG735_RS03785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JG735_RS03790	COG0750	zinc metalloprotease
JG735_RS03795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JG735_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
JG735_RS03805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JG735_RS03815	COG0167	dihydroorotate dehydrogenase activity
JG735_RS03820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JG735_RS03825	COG0012	GTP binding
JG735_RS03830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JG735_RS03835	COG0586	Pfam SNARE associated Golgi protein
JG735_RS03840	COG0133	tryptophan synthase activity
JG735_RS03845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JG735_RS03850	COG0698	ribose 5-phosphate isomerase
JG735_RS03855	COG1994	Peptidase M50
JG735_RS03860	COG0681	Belongs to the peptidase S26 family
JG735_RS03865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JG735_RS03880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JG735_RS03885	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
JG735_RS03885	COG3261	NADH dehydrogenase
JG735_RS03890	COG0651	ATP synthesis coupled electron transport
JG735_RS03905	COG0651	ATP synthesis coupled electron transport
JG735_RS03915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JG735_RS03930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JG735_RS04015	COG0251	oxidation-reduction process
JG735_RS04020	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JG735_RS04025	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JG735_RS04030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JG735_RS04035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JG735_RS04040	COG0585	pseudouridine synthase activity
JG735_RS04045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JG735_RS04055	COG1192	Involved in chromosome partitioning
JG735_RS04060	COG1475	DNA binding
JG735_RS04070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JG735_RS04075	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JG735_RS04080	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JG735_RS04085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JG735_RS04090	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JG735_RS04095	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JG735_RS04100	COG0811	peptide transport
JG735_RS04105	COG0848	biopolymer transport protein
JG735_RS04115	COG0823	Involved in the tonB-independent uptake of proteins
JG735_RS04130	COG1047	Peptidyl-prolyl cis-trans
JG735_RS04135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JG735_RS04145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JG735_RS04150	COG0037	tRNA processing
JG735_RS04160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JG735_RS04170	COG5001	Diguanylate cyclase
JG735_RS04170	COG3300	MHYT domain
JG735_RS04175	COG0840	transmembrane signaling receptor activity
JG735_RS04190	COG0070	glutamate synthase
JG735_RS04190	COG0069	glutamate synthase activity
JG735_RS04190	COG0067	glutamate synthase
JG735_RS04195	COG0493	'glutamate synthase
JG735_RS04205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JG735_RS04210	COG0352	thiamine-phosphate diphosphorylase activity
JG735_RS04215	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JG735_RS04225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JG735_RS04235	COG0730	response to heat
JG735_RS04240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JG735_RS04255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JG735_RS04255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JG735_RS04260	COG1333	cytochrome c biogenesis protein
JG735_RS04260	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JG735_RS04265	COG0484	heat shock protein binding
JG735_RS04270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JG735_RS04275	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JG735_RS04280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JG735_RS04285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JG735_RS04290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JG735_RS04300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JG735_RS04305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JG735_RS04320	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JG735_RS04345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JG735_RS04360	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JG735_RS04365	COG0629	single-stranded DNA binding
JG735_RS04370	COG0360	Binds together with S18 to 16S ribosomal RNA
JG735_RS04380	COG0557	exoribonuclease II activity
JG735_RS04385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JG735_RS04390	COG2861	carbohydrate metabolic process
JG735_RS04395	COG0471	metal ion transport
JG735_RS04410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JG735_RS04420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JG735_RS04455	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JG735_RS04460	COG0805	protein transport
JG735_RS04465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JG735_RS04475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JG735_RS04480	COG0494	nUDIX hydrolase
JG735_RS04485	COG0527	aspartate kinase activity
JG735_RS04495	COG0470	DNA polymerase III
JG735_RS04500	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JG735_RS04510	COG1858	cytochrome C peroxidase
JG735_RS04515	COG5002	protein histidine kinase activity
JG735_RS04515	COG5001	Diguanylate cyclase
JG735_RS04520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JG735_RS04530	COG0196	riboflavin kinase activity
JG735_RS04535	COG1331	Highly conserved protein containing a thioredoxin domain
JG735_RS04540	COG4106	trans-aconitate 2-methyltransferase activity
JG735_RS04545	COG3706	GGDEF domain
JG735_RS04550	COG2404	hydrolase activity, acting on ester bonds
JG735_RS04555	COG1959	2 iron, 2 sulfur cluster binding
JG735_RS04560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JG735_RS04565	COG1420	regulation of RNA biosynthetic process
JG735_RS04570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JG735_RS04575	COG0443	Heat shock 70 kDa protein
JG735_RS04595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG735_RS04600	COG1331	Highly conserved protein containing a thioredoxin domain
JG735_RS04605	COG4232	protein-disulfide reductase activity
JG735_RS04615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JG735_RS04625	COG0463	Glycosyl transferase, family 2
JG735_RS04635	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JG735_RS04640	COG1355	regulation of microtubule-based process
JG735_RS04645	COG0101	tRNA pseudouridine synthase activity
JG735_RS04655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JG735_RS04660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JG735_RS04665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JG735_RS04670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JG735_RS04675	COG1132	(ABC) transporter
JG735_RS04680	COG0215	cysteine-tRNA ligase activity
JG735_RS04685	COG0728	peptidoglycan biosynthetic process
JG735_RS04695	COG0632	four-way junction helicase activity
JG735_RS04700	COG1181	Belongs to the D-alanine--D-alanine ligase family
JG735_RS04705	COG2081	HI0933 family
JG735_RS04710	COG2860	membrane
JG735_RS04725	COG1254	Belongs to the acylphosphatase family
JG735_RS04730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JG735_RS04760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JG735_RS04765	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JG735_RS04770	COG0343	queuine tRNA-ribosyltransferase activity
JG735_RS04780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JG735_RS04790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JG735_RS04795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JG735_RS04805	COG0521	Mo-molybdopterin cofactor biosynthetic process
JG735_RS04825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JG735_RS04835	COG5001	Diguanylate cyclase
JG735_RS04835	COG3300	MHYT domain
JG735_RS04840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JG735_RS04860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JG735_RS04885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JG735_RS04905	COG2104	thiamine diphosphate biosynthetic process
JG735_RS04910	COG0736	holo-[acyl-carrier-protein] synthase activity
JG735_RS04915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JG735_RS04925	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JG735_RS04935	COG0552	protein localization to endoplasmic reticulum
JG735_RS04950	COG1418	mRNA catabolic process
JG735_RS04965	COG0500	methyltransferase
JG735_RS04970	COG0647	UMP catabolic process
JG735_RS04980	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JG735_RS04980	COG2050	protein possibly involved in aromatic compounds catabolism
JG735_RS04985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JG735_RS04990	COG2833	Protein of unknown function (DUF455)
JG735_RS04995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JG735_RS05000	COG1663	tetraacyldisaccharide 4'-kinase activity
JG735_RS05005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JG735_RS05010	COG1324	tolerance protein
JG735_RS05015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JG735_RS05025	COG0488	(ABC) transporter
JG735_RS05030	COG0501	Belongs to the peptidase M48B family
JG735_RS05035	COG2890	protein-(glutamine-N5) methyltransferase activity
JG735_RS05045	COG1127	ABC transporter
JG735_RS05050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JG735_RS05055	COG0849	cell division
JG735_RS05060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JG735_RS05065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JG735_RS05070	COG0275	rRNA processing
JG735_RS05090	COG0142	geranyltranstransferase activity
JG735_RS05095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JG735_RS05100	COG0442	prolyl-tRNA aminoacylation
JG735_RS05105	COG3030	protein affecting phage T7 exclusion by the F plasmid
JG735_RS05115	COG0181	hydroxymethylbilane synthase activity
JG735_RS05125	COG2151	metal-sulfur cluster biosynthetic enzyme
JG735_RS05135	COG0396	ATPase activity
JG735_RS05140	COG0719	Fe-S assembly protein
JG735_RS05150	COG0659	secondary active sulfate transmembrane transporter activity
JG735_RS05155	COG0525	valine-tRNA ligase activity
JG735_RS05165	COG1459	type II secretion system
JG735_RS05170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JG735_RS05220	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JG735_RS05225	COG0359	binds to the 23S rRNA
JG735_RS05230	COG0137	argininosuccinate synthase activity
JG735_RS05235	COG0742	ribosomal rna small subunit methyltransferase
JG735_RS05255	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JG735_RS05260	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JG735_RS05275	COG0134	indole-3-glycerol-phosphate synthase activity
JG735_RS05295	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JG735_RS05310	COG0077	Prephenate dehydratase
JG735_RS05310	COG1605	Chorismate mutase
JG735_RS05315	COG0582	viral genome integration into host DNA
JG735_RS05325	COG0375	protein maturation
JG735_RS05330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JG735_RS05330	COG1024	Enoyl-CoA hydratase
JG735_RS05335	COG0309	Hydrogenase expression formation protein (HypE)
JG735_RS05340	COG0409	Hydrogenase expression formation protein
JG735_RS05345	COG0298	carbon dioxide binding
JG735_RS05350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JG735_RS05365	COG1252	NADH dehydrogenase
JG735_RS05370	COG3022	response to hydroperoxide
JG735_RS05375	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
JG735_RS05390	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
JG735_RS05395	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
JG735_RS05400	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
JG735_RS05420	COG2226	methyltransferase
JG735_RS05430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JG735_RS05435	COG0789	Transcriptional regulator
JG735_RS05440	COG0484	heat shock protein binding
JG735_RS05445	COG0326	Molecular chaperone. Has ATPase activity
JG735_RS05455	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JG735_RS05470	COG0058	SHG alpha-glucan phosphorylase activity
JG735_RS05480	COG0166	Belongs to the GPI family
JG735_RS05485	COG0058	SHG alpha-glucan phosphorylase activity
JG735_RS05495	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JG735_RS05505	COG1449	Belongs to the glycosyl hydrolase 57 family
JG735_RS05515	COG1940	carbohydrate kinase activity
JG735_RS05520	COG0297	glycogen (starch) synthase activity
JG735_RS05525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JG735_RS05535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JG735_RS05540	COG0022	dehydrogenase e1 component
JG735_RS05545	COG0508	dehydrogenase complex catalyzes the overall conversion of
JG735_RS05550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JG735_RS05555	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JG735_RS05580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JG735_RS05585	COG0045	succinate-CoA ligase (ADP-forming) activity
JG735_RS05585	COG1042	CoA-binding domain protein
JG735_RS05585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG735_RS05590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JG735_RS05590	COG0574	Belongs to the PEP-utilizing enzyme family
JG735_RS05595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JG735_RS05610	COG1509	lysine 2,3-aminomutase activity
JG735_RS05615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JG735_RS05620	COG2201	protein-glutamate methylesterase activity
JG735_RS05630	COG3300	MHYT domain
JG735_RS05630	COG5001	Diguanylate cyclase
JG735_RS05635	COG0745	RESPONSE REGULATOR receiver
JG735_RS05640	COG3850	Histidine kinase
JG735_RS05640	COG5002	protein histidine kinase activity
JG735_RS05670	COG2010	Cytochrome c
JG735_RS05695	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JG735_RS05705	COG2217	Heavy metal translocating P-type atpase
JG735_RS05710	COG0745	RESPONSE REGULATOR receiver
JG735_RS05715	COG0642	Histidine kinase
JG735_RS05720	COG0205	6-phosphofructokinase activity
JG735_RS05750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JG735_RS05765	COG0501	Belongs to the peptidase M48B family
JG735_RS05770	COG3608	succinylglutamate desuccinylase aspartoacylase
JG735_RS05775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JG735_RS05785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JG735_RS05790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JG735_RS05800	COG0706	membrane insertase activity
JG735_RS05805	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JG735_RS05810	COG0594	ribonuclease P activity
JG735_RS05815	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JG735_RS05825	COG0542	response to heat
JG735_RS05830	COG0793	Belongs to the peptidase S41A family
JG735_RS05835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JG735_RS05840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JG735_RS05845	COG0047	phosphoribosylformylglycinamidine synthase activity
JG735_RS05855	COG0204	Acyl-transferase
JG735_RS05860	COG0444	Belongs to the ABC transporter superfamily
JG735_RS05865	COG2824	Alkylphosphonate utilization operon protein PhnA
JG735_RS05870	COG2201	protein-glutamate methylesterase activity
JG735_RS05875	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JG735_RS05885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JG735_RS05895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JG735_RS05900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JG735_RS05905	COG3012	SEC-C Motif Domain Protein
JG735_RS05910	COG0352	thiamine-phosphate diphosphorylase activity
JG735_RS05920	COG0356	it plays a direct role in the translocation of protons across the membrane
JG735_RS05935	COG0802	atpase or kinase
JG735_RS05940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JG735_RS05945	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JG735_RS05950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JG735_RS05955	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JG735_RS05975	COG3962	Belongs to the TPP enzyme family
JG735_RS05980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JG735_RS05980	COG0674	pyruvate-flavodoxin oxidoreductase activity
JG735_RS05995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JG735_RS06000	COG0045	succinate-CoA ligase (ADP-forming) activity
JG735_RS06005	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JG735_RS06015	COG0039	L-malate dehydrogenase activity
JG735_RS06025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JG735_RS06040	COG0653	protein targeting
JG735_RS06050	COG1049	propionate catabolic process, 2-methylcitrate cycle
JG735_RS06060	COG1196	nuclear chromosome segregation
JG735_RS06060	COG1674	ftsk spoiiie
JG735_RS06065	COG0776	regulation of translation
JG735_RS06080	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JG735_RS06085	COG2894	cell division
JG735_RS06095	COG0163	prenyltransferase activity
JG735_RS06100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JG735_RS06105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JG735_RS06110	COG0124	histidyl-tRNA synthetase
JG735_RS06115	COG1166	arginine decarboxylase activity
JG735_RS06120	COG1045	serine acetyltransferase
JG735_RS06125	COG0436	Aminotransferase
JG735_RS06130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JG735_RS06140	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JG735_RS06145	COG0440	acetolactate synthase activity
JG735_RS06150	COG0028	Belongs to the TPP enzyme family
JG735_RS06160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JG735_RS06165	COG1832	CoA-binding protein
JG735_RS06170	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JG735_RS06190	COG0688	phosphatidylethanolamine metabolic process
JG735_RS06195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JG735_RS06215	COG1763	Mo-molybdopterin cofactor biosynthetic process
JG735_RS06220	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JG735_RS06230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JG735_RS06230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JG735_RS06240	COG0387	Pfam Sodium calcium exchanger
JG735_RS06245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JG735_RS06250	COG0531	amino acid
JG735_RS06255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JG735_RS06260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JG735_RS06265	COG0840	transmembrane signaling receptor activity
JG735_RS06270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JG735_RS06280	COG0768	penicillin binding
JG735_RS06295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JG735_RS06310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JG735_RS06315	COG0131	Imidazoleglycerol-phosphate dehydratase
JG735_RS06320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JG735_RS06325	COG0741	lytic transglycosylase activity
JG735_RS06325	COG1388	LysM domain
JG735_RS06330	COG0084	hydrolase, TatD family'
JG735_RS06335	COG0497	DNA recombination
JG735_RS06340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JG735_RS06345	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JG735_RS06355	COG0563	adenylate kinase activity
JG735_RS06360	COG1546	Belongs to the CinA family
JG735_RS06360	COG1058	Belongs to the CinA family
JG735_RS06370	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JG735_RS06380	COG1959	2 iron, 2 sulfur cluster binding
JG735_RS06385	COG0860	N-Acetylmuramoyl-L-alanine amidase
JG735_RS06395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JG735_RS06400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JG735_RS06405	COG1758	RNA polymerase activity
JG735_RS06410	COG0528	UMP kinase activity
JG735_RS06425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JG735_RS06430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JG735_RS06440	COG0564	pseudouridine synthase activity
JG735_RS06445	COG0772	Belongs to the SEDS family
JG735_RS06480	COG3108	Peptidase M15
JG735_RS06485	COG2989	Protein conserved in bacteria
JG735_RS06500	COG1132	(ABC) transporter
JG735_RS06515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JG735_RS06520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JG735_RS06520	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JG735_RS06535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JG735_RS06540	COG0788	formyltetrahydrofolate deformylase activity
JG735_RS06550	COG0473	3-isopropylmalate dehydrogenase activity
JG735_RS06555	COG0066	3-isopropylmalate dehydratase activity
JG735_RS06560	COG3290	protein histidine kinase activity
JG735_RS06560	COG0840	transmembrane signaling receptor activity
JG735_RS06585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JG735_RS06590	COG3150	esterase
JG735_RS06615	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JG735_RS06615	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JG735_RS06630	COG1086	Polysaccharide biosynthesis protein
JG735_RS06635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JG735_RS06640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JG735_RS06650	COG1215	transferase activity, transferring glycosyl groups
JG735_RS06675	COG1213	nucleotidyl transferase
JG735_RS06675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JG735_RS06685	COG2226	methyltransferase
JG735_RS06690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JG735_RS06695	COG1193	negative regulation of DNA recombination
JG735_RS06700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JG735_RS06740	COG0436	Aminotransferase
JG735_RS06760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JG735_RS06765	COG0475	glutathione-regulated potassium exporter activity
JG735_RS06775	COG2873	o-acetylhomoserine
JG735_RS06780	COG0517	IMP dehydrogenase activity
JG735_RS06780	COG0516	GMP reductase activity
JG735_RS06785	COG0154	amidase activity
JG735_RS06790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JG735_RS06795	COG1546	Belongs to the CinA family
JG735_RS06795	COG1058	Belongs to the CinA family
JG735_RS06835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JG735_RS06835	COG1796	DNA polymerase
JG735_RS06850	COG0642	Histidine kinase
JG735_RS06865	COG2863	cytochrome
JG735_RS06870	COG3118	belongs to the thioredoxin family
JG735_RS06900	COG1073	alpha beta
JG735_RS06930	COG3630	sodium ion export across plasma membrane
JG735_RS06950	COG1881	PFAM PEBP family protein
JG735_RS06955	COG0560	Phosphoserine phosphatase
JG735_RS06975	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JG735_RS06980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JG735_RS06995	COG0673	inositol 2-dehydrogenase activity
JG735_RS07005	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JG735_RS07010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JG735_RS07040	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JG735_RS07045	COG1185	polyribonucleotide nucleotidyltransferase activity
JG735_RS07050	COG0484	heat shock protein binding
JG735_RS07055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JG735_RS07075	COG0519	Catalyzes the synthesis of GMP from XMP
JG735_RS07075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JG735_RS07080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JG735_RS07085	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JG735_RS07095	COG0322	excinuclease ABC activity
JG735_RS07120	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JG735_RS07125	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JG735_RS07130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JG735_RS07155	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JG735_RS07160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JG735_RS07165	COG0612	Peptidase, M16
JG735_RS07170	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JG735_RS07180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JG735_RS07185	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JG735_RS07200	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JG735_RS07220	COG0668	transmembrane transport
JG735_RS07225	COG1160	GTP binding
JG735_RS07230	COG0180	Tryptophanyl-tRNA synthetase
JG735_RS07245	COG1993	acr, cog1993
JG735_RS07250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JG735_RS07265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JG735_RS07275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JG735_RS07305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JG735_RS07310	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JG735_RS07355	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JG735_RS07400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JG735_RS07410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JG735_RS07415	COG1183	phosphatidylcholine synthase activity
JG735_RS07420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JG735_RS07425	COG2264	protein methyltransferase activity
JG735_RS07430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JG735_RS07435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JG735_RS07450	COG2194	sulfuric ester hydrolase activity
JG735_RS07465	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JG735_RS07490	COG0848	biopolymer transport protein
JG735_RS07495	COG0811	peptide transport
JG735_RS07500	COG5002	protein histidine kinase activity
JG735_RS07500	COG3850	Histidine kinase
JG735_RS07510	COG0418	dihydroorotase activity
JG735_RS07520	COG0004	ammonium transporteR
JG735_RS07525	COG0347	Belongs to the P(II) protein family
JG735_RS07530	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JG735_RS07550	COG0367	asparagine synthase
JG735_RS07580	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JG735_RS07585	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JG735_RS07585	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JG735_RS07605	COG2217	Heavy metal translocating P-type atpase
JG735_RS07620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JG735_RS07625	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JG735_RS07630	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JG735_RS07640	COG1692	metallophosphoesterase
JG735_RS07645	COG0179	Fumarylacetoacetate (FAA) hydrolase
JG735_RS07650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JG735_RS07665	COG0495	leucyl-tRNA aminoacylation
JG735_RS07670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JG735_RS07675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JG735_RS07680	COG1862	Preprotein translocase
JG735_RS07685	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JG735_RS07715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JG735_RS07720	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JG735_RS07725	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JG735_RS07730	COG3706	GGDEF domain
JG735_RS07735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JG735_RS07740	COG0037	tRNA processing
JG735_RS07760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JG735_RS07770	COG0195	Participates in both transcription termination and antitermination
JG735_RS07775	COG0601	transmembrane transport
JG735_RS07790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JG735_RS07795	COG0149	triose-phosphate isomerase activity
JG735_RS07800	COG0126	phosphoglycerate kinase activity
JG735_RS07810	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JG735_RS07815	COG0799	negative regulation of ribosome biogenesis
JG735_RS07820	COG0018	arginyl-trna synthetase
JG735_RS07825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JG735_RS07830	COG0194	GDP metabolic process
JG735_RS07845	COG0335	large ribosomal subunit rRNA binding
JG735_RS07850	COG0336	Belongs to the RNA methyltransferase TrmD family
JG735_RS07855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JG735_RS07860	COG1837	Belongs to the UPF0109 family
JG735_RS07865	COG0228	four-way junction DNA binding
JG735_RS07870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JG735_RS07875	COG0564	pseudouridine synthase activity
JG735_RS07885	COG1519	Transferase
JG735_RS07895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JG735_RS07900	COG0752	glycyl-tRNA synthetase alpha subunit
JG735_RS07915	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JG735_RS07925	COG0826	peptidase U32
JG735_RS07940	COG0174	glutamine synthetase
JG735_RS07950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JG735_RS07955	COG0444	Belongs to the ABC transporter superfamily
JG735_RS07960	COG0156	8-amino-7-oxononanoate synthase activity
JG735_RS07965	COG0515	serine threonine protein kinase
JG735_RS07965	COG2815	serine threonine protein kinase
JG735_RS07970	COG0424	maF-like protein
JG735_RS07975	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JG735_RS07985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JG735_RS07990	COG0768	penicillin binding
JG735_RS07995	COG0772	Belongs to the SEDS family
JG735_RS08000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JG735_RS08005	COG3706	GGDEF domain
JG735_RS08010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JG735_RS08015	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JG735_RS08025	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JG735_RS08030	COG0052	Belongs to the universal ribosomal protein uS2 family
JG735_RS08035	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JG735_RS08050	COG1012	belongs to the aldehyde dehydrogenase family
JG735_RS08065	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JG735_RS08065	COG0140	phosphoribosyl-ATP diphosphatase activity
JG735_RS08075	COG1242	4 iron, 4 sulfur cluster binding
JG735_RS08080	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JG735_RS08085	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JG735_RS08090	COG0492	ferredoxin-NADP+ reductase activity
JG735_RS08095	COG3118	belongs to the thioredoxin family
JG735_RS08100	COG0792	nuclease activity
JG735_RS08105	COG3383	formate dehydrogenase (NAD+) activity
JG735_RS08110	COG0460	homoserine dehydrogenase
JG735_RS08115	COG0436	Aminotransferase
JG735_RS08130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JG735_RS08135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JG735_RS08140	COG0254	rRNA binding
JG735_RS08160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JG735_RS08220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JG735_RS08240	COG0303	'Molybdopterin
JG735_RS08250	COG0720	synthase
JG735_RS08255	COG0602	queuosine metabolic process
JG735_RS08260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JG735_RS08270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JG735_RS08275	COG0723	plastoquinol--plastocyanin reductase activity
JG735_RS08285	COG0445	tRNA wobble uridine modification
JG735_RS08335	COG1013	pyruvate-flavodoxin oxidoreductase activity
JG735_RS08340	COG0674	pyruvate-flavodoxin oxidoreductase activity
JG735_RS08345	COG1144	Oxidoreductase
JG735_RS08350	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JG735_RS08355	COG0546	phosphoglycolate phosphatase activity
JG735_RS08370	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JG735_RS08375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JG735_RS08390	COG0348	domain, Protein
JG735_RS08415	COG3278	Belongs to the heme-copper respiratory oxidase family
JG735_RS08420	COG0745	RESPONSE REGULATOR receiver
JG735_RS08440	COG0505	Belongs to the CarA family
JG735_RS08450	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JG735_RS08455	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JG735_RS08460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JG735_RS08465	COG0071	Belongs to the small heat shock protein (HSP20) family
JG735_RS08475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JG735_RS08480	COG2814	Major facilitator Superfamily
JG735_RS08490	COG0303	'Molybdopterin
JG735_RS08495	COG2902	Dehydrogenase
JG735_RS08500	COG0314	molybdopterin synthase activity
JG735_RS08510	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
JG735_RS08515	COG1858	cytochrome C peroxidase
JG735_RS08520	COG5001	Diguanylate cyclase
JG735_RS08520	COG3300	MHYT domain
JG735_RS08525	COG0281	malic enzyme
JG735_RS08525	COG0280	phosphate acetyltransferase
JG735_RS08530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JG735_RS08535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JG735_RS08540	COG2171	N-acyltransferase activity
JG735_RS08550	COG0439	Biotin carboxylase
JG735_RS08555	COG0511	ligase activity, forming carbon-carbon bonds
JG735_RS08560	COG0717	Belongs to the dCTP deaminase family
JG735_RS08565	COG3287	FIST C domain
JG735_RS08565	COG2200	EAL domain
JG735_RS08565	COG2199	diguanylate cyclase activity
JG735_RS08570	COG0367	asparagine synthase
JG735_RS08580	COG0598	Magnesium transport protein CorA
JG735_RS08590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JG735_RS08600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JG735_RS08605	COG0569	domain protein
JG735_RS08605	COG0475	glutathione-regulated potassium exporter activity
JG735_RS08620	COG0148	phosphopyruvate hydratase activity
JG735_RS08625	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JG735_RS08630	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
JG735_RS08635	COG2199	diguanylate cyclase activity
JG735_RS08640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JG735_RS08645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JG735_RS08650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JG735_RS08665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JG735_RS08670	COG0575	Belongs to the CDS family
JG735_RS08680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JG735_RS08685	COG1489	DNA binding
JG735_RS08700	COG1136	(ABC) transporter
JG735_RS08700	COG0577	efflux transmembrane transporter activity
JG735_RS08705	COG1136	(ABC) transporter
JG735_RS08705	COG0577	efflux transmembrane transporter activity
JG735_RS08765	COG0315	cyclic pyranopterin monophosphate synthase activity
JG735_RS08785	COG0513	Belongs to the DEAD box helicase family
JG735_RS08800	COG0483	inositol monophosphate 1-phosphatase activity
JG735_RS08805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JG735_RS08810	COG0745	RESPONSE REGULATOR receiver
JG735_RS08815	COG0642	Histidine kinase
JG735_RS08820	COG0494	nUDIX hydrolase
JG735_RS08840	COG2814	Major facilitator Superfamily
JG735_RS08850	COG1309	transcriptional regulator
JG735_RS08870	COG1129	ABC transporter
JG735_RS08870	COG0842	Transport permease protein
JG735_RS08875	COG0842	Transport permease protein
JG735_RS08880	COG0842	Transport permease protein
JG735_RS08900	COG1511	domain protein
JG735_RS08900	COG3264	Mechanosensitive ion channel
JG735_RS08905	COG0668	transmembrane transport
JG735_RS08910	COG5002	protein histidine kinase activity
JG735_RS08910	COG5001	Diguanylate cyclase
JG735_RS08920	COG0492	ferredoxin-NADP+ reductase activity
JG735_RS08940	COG1309	transcriptional regulator
JG735_RS08945	COG3706	GGDEF domain
JG735_RS08950	COG0569	domain protein
JG735_RS08955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JG735_RS08965	COG0038	chloride channel
JG735_RS08975	COG0531	amino acid
JG735_RS08990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JG735_RS09010	COG2205	protein histidine kinase activity
JG735_RS09015	COG0745	RESPONSE REGULATOR receiver
JG735_RS09030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JG735_RS09035	COG3300	MHYT domain
JG735_RS09035	COG5001	Diguanylate cyclase
JG735_RS09040	COG1110	DNA topoisomerase II activity
JG735_RS09055	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JG735_RS09065	COG2172	sigma factor antagonist activity
JG735_RS09070	COG1473	amidohydrolase
JG735_RS09110	COG1522	sequence-specific DNA binding
JG735_RS09115	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JG735_RS09115	COG1648	precorrin-2 dehydrogenase activity
JG735_RS09140	COG1131	(ABC) transporter
JG735_RS09145	COG0348	domain, Protein
JG735_RS09160	COG0437	4 iron, 4 sulfur cluster binding
JG735_RS09180	COG1587	Uroporphyrinogen-III synthase
JG735_RS09180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JG735_RS09195	COG0535	radical SAM domain protein
JG735_RS09200	COG2010	Cytochrome c
JG735_RS09215	COG3256	nitric oxide reductase
JG735_RS09220	COG2010	Cytochrome c
JG735_RS09230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JG735_RS09245	COG0840	transmembrane signaling receptor activity
JG735_RS09265	COG3043	anaerobic respiration
JG735_RS09270	COG0348	domain, Protein
JG735_RS09275	COG0437	4 iron, 4 sulfur cluster binding
JG735_RS09280	COG0243	molybdopterin cofactor binding
JG735_RS09300	COG2151	metal-sulfur cluster biosynthetic enzyme
JG735_RS09335	COG1140	nitrate reductase beta subunit
JG735_RS09340	COG0243	molybdopterin cofactor binding
JG735_RS09360	COG0489	protein tyrosine kinase activity
JG735_RS09390	COG3258	Cytochrome c
JG735_RS09410	COG5002	protein histidine kinase activity
JG735_RS09455	COG0670	Belongs to the BI1 family
JG735_RS09460	COG0352	thiamine-phosphate diphosphorylase activity
JG735_RS09475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JG735_RS09485	COG0233	cytoplasmic translational termination
JG735_RS09490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JG735_RS09500	COG2814	Major facilitator Superfamily
JG735_RS09505	COG0840	transmembrane signaling receptor activity
JG735_RS09515	COG0778	Nitroreductase
JG735_RS09525	COG1217	gtp-binding protein TYPA
JG735_RS09530	COG0546	phosphoglycolate phosphatase activity
JG735_RS09535	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JG735_RS09555	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JG735_RS09615	COG1116	anion transmembrane transporter activity
JG735_RS09620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JG735_RS09650	COG1528	Iron-storage protein
JG735_RS09680	COG0716	FMN binding