locus-tag	class	description
DSM104443_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
DSM104443_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DSM104443_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DSM104443_RS00025	ENOG4105ECQ	AraC Family Transcriptional Regulator
DSM104443_RS00040	ENOG4105C79	DNA protecting protein DprA
DSM104443_RS00055	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
DSM104443_RS00065	ENOG4105ES5	Histidine kinase
DSM104443_RS00070	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DSM104443_RS00085	ENOG4108JQ7	(ABC) transporter
DSM104443_RS00090	ENOG4105C3U	ABC transporter
DSM104443_RS00095	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS00100	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS00105	ENOG4105DEF	Extracellular solute-binding protein, family 5
DSM104443_RS00110	ENOG4105WAP	TPR repeat-containing protein
DSM104443_RS00115	ENOG4105D49	3-dehydroquinate synthase
DSM104443_RS00125	ENOG4105E4G	Type IV pilus
DSM104443_RS00150	ENOG4108JQC	penicillin-binding protein 1A
DSM104443_RS00160	ENOG4105D52	delta-aminolevulinic acid dehydratase
DSM104443_RS00165	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
DSM104443_RS00175	ENOG4105BZU	Histidine kinase
DSM104443_RS00180	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DSM104443_RS00185	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
DSM104443_RS00190	ENOG4105DWF	phosphomethylpyrimidine kinase
DSM104443_RS00195	ENOG4105VCQ	rubredoxin
DSM104443_RS00200	ENOG4108UNF	response regulator
DSM104443_RS00205	ENOG4105M3Z	response regulator
DSM104443_RS00215	ENOG4105C8Q	Methyl-accepting chemotaxis
DSM104443_RS00235	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
DSM104443_RS00245	ENOG4105BZU	Histidine kinase
DSM104443_RS00250	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
DSM104443_RS00260	ENOG4105CW7	secretion protein, HlyD family
DSM104443_RS00265	ENOG4105CJ1	ABC, transporter
DSM104443_RS00270	ENOG4107QWP	ABC-2 type transporter
DSM104443_RS00275	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
DSM104443_RS00280	ENOG4105DFG	type I secretion outer membrane protein
DSM104443_RS00285	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
DSM104443_RS00290	ENOG4105D16	lipopolysaccharide heptosyltransferase i
DSM104443_RS00310	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
DSM104443_RS00335	ENOG4105C2X	Arabinose 5-phosphate isomerase
DSM104443_RS00340	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
DSM104443_RS00350	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
DSM104443_RS00355	ENOG4108IUZ	ABC transporter
DSM104443_RS00360	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DSM104443_RS00365	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
DSM104443_RS00370	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
DSM104443_RS00375	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
DSM104443_RS00380	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
DSM104443_RS00390	ENOG4105CEN	a g-specific adenine glycosylase
DSM104443_RS00405	ENOG4108HRK	Histidine kinase
DSM104443_RS00410	ENOG4108VAC	response regulator
DSM104443_RS00415	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
DSM104443_RS00420	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
DSM104443_RS00430	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
DSM104443_RS00440	ENOG4105CSA	Coproporphyrinogen iii oxidase
DSM104443_RS00445	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DSM104443_RS00450	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
DSM104443_RS00455	ENOG4108ZF3	Phosphatase
DSM104443_RS00460	ENOG4105D9P	serine threonine protein kinase
DSM104443_RS00465	ENOG4105DSJ	YicC domain protein
DSM104443_RS00470	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
DSM104443_RS00475	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
DSM104443_RS00480	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DSM104443_RS00485	ENOG4105KME	endoribonuclease L-psp
DSM104443_RS00490	ENOG4105CB5	ATP-dependent DNA helicase recG
DSM104443_RS00495	ENOG4105RUM	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
DSM104443_RS00500	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
DSM104443_RS00505	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
DSM104443_RS00510	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
DSM104443_RS00540	ENOG4105DA5	(ABC) transporter
DSM104443_RS00545	ENOG4105CHH	sulfate transporter
DSM104443_RS00565	ENOG4108RMU	ferritin dps family protein
DSM104443_RS00570	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
DSM104443_RS00575	ENOG4105CZX	twitching motility protein
DSM104443_RS00580	ENOG4105CZX	twitching motility protein
DSM104443_RS00585	ENOG4105DFA	alanine racemase domain protein
DSM104443_RS00590	ENOG4105II7	pyrroline-5-carboxylate reductase
DSM104443_RS00595	ENOG4108VIA	integral membrane protein
DSM104443_RS00615	ENOG4105CEY	Amp-dependent synthetase and ligase
DSM104443_RS00620	ENOG4105C1G	acyl-Coa dehydrogenase
DSM104443_RS00630	ENOG4105CHR	reductase
DSM104443_RS00635	ENOG4105CHU	acetyl-coa acetyltransferase
DSM104443_RS00640	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DSM104443_RS00645	ENOG4108IV0	ABC, transporter
DSM104443_RS00650	ENOG4105C2J	ABC transporter
DSM104443_RS00660	ENOG4105C32	Amino acid ABC transporter (Permease)
DSM104443_RS00670	ENOG4105CC9	acyl-Coa dehydrogenase
DSM104443_RS00675	ENOG4105C1G	acyl-Coa dehydrogenase
DSM104443_RS00685	ENOG4108N5B	2-phosphosulfolactate phosphatase
DSM104443_RS00690	ENOG4105CPQ	Dehydrogenase
DSM104443_RS00695	ENOG4107258	Transcriptional regulator
DSM104443_RS00710	ENOG4105C03	ribonuclease
DSM104443_RS00715	ENOG4108Z03	MAF-like protein
DSM104443_RS00720	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
DSM104443_RS00725	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
DSM104443_RS00730	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
DSM104443_RS00735	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
DSM104443_RS00750	ENOG4105C8T	Leucyl-tRNA synthetase
DSM104443_RS00765	ENOG4105C4R	Atp-dependent dna helicase
DSM104443_RS00775	ENOG4105CUV	Homoserine Kinase
DSM104443_RS00785	ENOG4108URH	decarboxylase
DSM104443_RS00790	ENOG4105C2M	dna polymerase I
DSM104443_RS00800	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DSM104443_RS00865	ENOG4105D9P	serine threonine protein kinase
DSM104443_RS00875	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
DSM104443_RS00885	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
DSM104443_RS00905	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
DSM104443_RS00910	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
DSM104443_RS00915	ENOG4105DC1	bifunctional purine biosynthesis protein purh
DSM104443_RS00920	ENOG4105C12	Phosphoribosylglycinamide synthetase
DSM104443_RS00935	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
DSM104443_RS00960	ENOG4105BZU	Histidine kinase
DSM104443_RS00965	ENOG4105D9P	serine threonine protein kinase
DSM104443_RS00975	ENOG4108IV0	ABC, transporter
DSM104443_RS00980	ENOG4105C0Z	ABC transporter
DSM104443_RS00985	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
DSM104443_RS00995	ENOG4105C32	Amino acid ABC transporter (Permease)
DSM104443_RS01010	ENOG4105W2Z	cytochrome C, class I
DSM104443_RS01015	ENOG4105C7Z	Conserved Protein
DSM104443_RS01030	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DSM104443_RS01060	ENOG4105DXI	Major Facilitator superfamily
DSM104443_RS01080	ENOG4105CPC	Aldo Keto reductase
DSM104443_RS01115	ENOG4105C01	Dihydroxy-acid dehydratase
DSM104443_RS01125	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
DSM104443_RS01130	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
DSM104443_RS01175	ENOG4105WH1	Two component transcriptional regulator luxr family
DSM104443_RS01225	ENOG4105VDW	Csbd family
DSM104443_RS01230	ENOG4105DSF	transport protein
DSM104443_RS01240	ENOG4107EXC	regulatoR
DSM104443_RS01245	ENOG4105JJR	Histidine kinase
DSM104443_RS01250	ENOG4105BZU	Histidine kinase
DSM104443_RS01265	ENOG4105C28	cystathionine
DSM104443_RS01410	ENOG4105XDF	Protein of unknown function (DUF1272)
DSM104443_RS01555	ENOG4105EV8	ectoine hydroxylase
DSM104443_RS01675	ENOG4105E0A	ABC, transporter
DSM104443_RS01680	ENOG4105EHG	Permease protein
DSM104443_RS01685	ENOG4105S10	periplasmic binding protein
DSM104443_RS01690	ENOG4105BZU	Histidine kinase
DSM104443_RS01700	ENOG4105D05	Receptor
DSM104443_RS01705	ENOG4108KS2	transglutaminase domain protein
DSM104443_RS01720	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
DSM104443_RS01725	ENOG4108MG3	formate dehydrogenase
DSM104443_RS01730	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
DSM104443_RS01740	ENOG4105PHD	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DSM104443_RS01745	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
DSM104443_RS01750	ENOG4105EM7	Selenocysteine-specific translation elongation factor
DSM104443_RS01765	ENOG4108VJC	ABC transporter, periplasmic molybdate-binding protein
DSM104443_RS01775	ENOG4105CDA	abc transporter atp-binding protein
DSM104443_RS01785	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
DSM104443_RS01790	ENOG4105E0C	molybdate abc transporter
DSM104443_RS01795	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
DSM104443_RS01800	ENOG4105F4R	Transcriptional regulator mode
DSM104443_RS01810	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
DSM104443_RS01820	ENOG4107QIZ	NADH dehydrogenase
DSM104443_RS01825	ENOG4108IEG	Formate dehydrogenase Alpha subunit
DSM104443_RS01830	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
DSM104443_RS01840	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DSM104443_RS01845	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
DSM104443_RS01850	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
DSM104443_RS01860	ENOG4107QHF	type ii secretion system protein e
DSM104443_RS01875	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
DSM104443_RS01880	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
DSM104443_RS01885	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
DSM104443_RS01900	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DSM104443_RS01905	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
DSM104443_RS01935	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
DSM104443_RS01950	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
DSM104443_RS01955	ENOG4105CAK	Cell division ATP-binding protein ftsE
DSM104443_RS01965	ENOG4106H78	methyltransferase
DSM104443_RS01970	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
DSM104443_RS01975	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
DSM104443_RS01985	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
DSM104443_RS01990	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
DSM104443_RS02000	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
DSM104443_RS02010	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DSM104443_RS02015	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
DSM104443_RS02020	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
DSM104443_RS02025	ENOG4105C3G	gtp-binding protein
DSM104443_RS02045	ENOG4105CDV	Ompa motb domain protein
DSM104443_RS02065	ENOG4105C9A	Phoh family
DSM104443_RS02070	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
DSM104443_RS02075	ENOG4108JU5	Magnesium and cobalt efflux protein
DSM104443_RS02080	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
DSM104443_RS02090	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
DSM104443_RS02095	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
DSM104443_RS02100	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
DSM104443_RS02125	ENOG4105C7K	acetolactate synthase
DSM104443_RS02130	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
DSM104443_RS02135	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
DSM104443_RS02140	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
DSM104443_RS02145	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
DSM104443_RS02150	ENOG4105EHM	Aminoglycoside phosphotransferase
DSM104443_RS02155	ENOG4108S0S	Nucleotidyl transferase
DSM104443_RS02160	ENOG4107RAQ	aminopeptidase
DSM104443_RS02165	ENOG4105D0A	hydroxylase
DSM104443_RS02185	ENOG4105CA3	membrane-bound lytic murein transglycosylase
DSM104443_RS02190	ENOG4105NWN	ApaG protein
DSM104443_RS02200	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
DSM104443_RS02210	ENOG4105DDQ	anthranilate synthase
DSM104443_RS02215	ENOG4107QYG	anthranilate phosphoribosyltransferase
DSM104443_RS02220	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DSM104443_RS02230	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
DSM104443_RS02240	ENOG4105IPI	Membrane
DSM104443_RS02245	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DSM104443_RS02250	ENOG4108UJD	30S ribosomal protein S9
DSM104443_RS02255	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
DSM104443_RS02270	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
DSM104443_RS02275	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
DSM104443_RS02280	ENOG41063SB	peptidase
DSM104443_RS02285	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DSM104443_RS02320	ENOG4105CHP	RNA polymerase
DSM104443_RS02325	ENOG4105GRZ	Ycii-related protein
DSM104443_RS02330	ENOG4105F8J	Adenylate Guanylate cyclase
DSM104443_RS02350	ENOG4105CD8	aminopeptidase N
DSM104443_RS02355	ENOG4105C1J	atp-dependent rna helicase
DSM104443_RS02365	ENOG41085AF	Cytochrome
DSM104443_RS02380	ENOG4105C5I	Dehydrogenase
DSM104443_RS02435	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DSM104443_RS02445	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
DSM104443_RS02450	ENOG4105KIP	Thioesterase
DSM104443_RS02455	ENOG4105CN1	protease
DSM104443_RS02470	ENOG4105BZU	Histidine kinase
DSM104443_RS02475	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DSM104443_RS02495	ENOG4105BZU	Histidine kinase
DSM104443_RS02500	ENOG4105DHJ	ABC, transporter
DSM104443_RS02510	ENOG4107EFR	Flavocytochrome c
DSM104443_RS02515	ENOG41079YP	Citrate utilization protein b
DSM104443_RS02520	ENOG4105MP9	class II Aldolase
DSM104443_RS02530	ENOG4105DG4	malate L-lactate dehydrogenase
DSM104443_RS02545	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
DSM104443_RS02550	ENOG4105CD5	CoA-binding domain protein
DSM104443_RS02570	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
DSM104443_RS02580	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DSM104443_RS02605	ENOG4105CHR	reductase
DSM104443_RS02640	ENOG4105C5H	ABC transporter
DSM104443_RS02680	ENOG4105C01	Dihydroxy-acid dehydratase
DSM104443_RS02685	ENOG4105EUB	pirin domain protein
DSM104443_RS02700	ENOG4105CPC	Aldo Keto reductase
DSM104443_RS02730	ENOG4107S2Z	UPF0761 membrane protein
DSM104443_RS02790	ENOG4106RE7	Cytochrome
DSM104443_RS02795	ENOG4108VAC	response regulator
DSM104443_RS02800	ENOG4108HRK	Histidine kinase
DSM104443_RS02870	ENOG4107RN3	metallophosphoesterase
DSM104443_RS02960	ENOG4105E0K	tonB-dependent siderophore receptor
DSM104443_RS02975	ENOG410624X	efflux transporter, rnd family, mfp subunit
DSM104443_RS02995	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
DSM104443_RS03000	ENOG4105CI0	Citrate lyase
DSM104443_RS03005	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
DSM104443_RS03035	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
DSM104443_RS03045	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DSM104443_RS03080	ENOG4105VEQ	Cold shock protein
DSM104443_RS03090	ENOG4106WF9	DNA-binding transcriptional regulator TorR
DSM104443_RS03120	ENOG4108NEV	two component transcriptional regulator, LytTR family
DSM104443_RS03145	ENOG4105CX6	glutaminyL-tRNA synthetase
DSM104443_RS03185	ENOG4105CXT	aspartate transcarbamylase
DSM104443_RS03195	ENOG4105CJ1	ABC, transporter
DSM104443_RS03215	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
DSM104443_RS03235	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
DSM104443_RS03240	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
DSM104443_RS03250	ENOG4105CN1	protease
DSM104443_RS03270	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
DSM104443_RS03275	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
DSM104443_RS03290	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
DSM104443_RS03310	ENOG4105CQB	FAD linked oxidase domain protein
DSM104443_RS03315	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
DSM104443_RS03335	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
DSM104443_RS03355	ENOG4107FW0	short-chain dehydrogenase reductase
DSM104443_RS03365	ENOG4105W4M	Transport-associated protein
DSM104443_RS03370	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
DSM104443_RS03375	ENOG41082RQ	UPF0102 protein
DSM104443_RS03385	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
DSM104443_RS03390	ENOG4105EKE	dihydroorotase
DSM104443_RS03410	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
DSM104443_RS03420	ENOG4105CXK	mandelate racemase muconate lactonizing
DSM104443_RS03430	ENOG4108IJ9	(ABC) transporter
DSM104443_RS03435	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
DSM104443_RS03460	ENOG4108V6E	Cell division protein mraZ
DSM104443_RS03465	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
DSM104443_RS03475	ENOG4105CJN	penicillin-binding protein
DSM104443_RS03480	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
DSM104443_RS03485	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
DSM104443_RS03490	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DSM104443_RS03495	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
DSM104443_RS03500	ENOG4105CNI	cell division protein FtsW
DSM104443_RS03505	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DSM104443_RS03510	ENOG4105DFU	Cell wall formation (By similarity)
DSM104443_RS03515	ENOG4105D4A	Cell wall formation (By similarity)
DSM104443_RS03520	ENOG4105CPF	Cell wall formation (By similarity)
DSM104443_RS03525	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
DSM104443_RS03530	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
DSM104443_RS03535	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
DSM104443_RS03550	ENOG4108NST	exported protein
DSM104443_RS03565	ENOG4105D78	K07001 NTE family protein
DSM104443_RS03585	ENOG4105DR5	peptidase
DSM104443_RS03590	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DSM104443_RS03595	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
DSM104443_RS03615	ENOG4105M6F	mutator MutT protein
DSM104443_RS03620	ENOG4105CI2	imidazolone-5-propionate hydrolase
DSM104443_RS03625	ENOG4105CH5	extracellular solute-binding protein, family 7
DSM104443_RS03630	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
DSM104443_RS03635	ENOG4105D7T	ABC transporter
DSM104443_RS03645	ENOG4105I5W	Transporter
DSM104443_RS03650	ENOG4107XGZ	Hydrolase
DSM104443_RS03655	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
DSM104443_RS03660	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
DSM104443_RS03665	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
DSM104443_RS03670	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DSM104443_RS03675	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
DSM104443_RS03685	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
DSM104443_RS03690	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
DSM104443_RS03700	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
DSM104443_RS03705	ENOG4105VW4	glutaredoxin 3
DSM104443_RS03710	ENOG4107YZP	Rhodanese domain protein
DSM104443_RS03725	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DSM104443_RS03735	ENOG4105CN1	protease
DSM104443_RS03740	ENOG4105D06	uba thif-type nad fad binding protein
DSM104443_RS03755	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DSM104443_RS03760	ENOG4105VCC	30S ribosomal protein S21
DSM104443_RS03770	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
DSM104443_RS03775	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DSM104443_RS03810	ENOG4105K4P	CoA-binding domain protein
DSM104443_RS03820	ENOG4107QX8	SPFH domain, Band 7 family protein
DSM104443_RS03835	ENOG4105W1Y	Transcriptional regulator
DSM104443_RS03855	ENOG4107QPN	acyl-Coa dehydrogenase
DSM104443_RS03860	ENOG4105CHU	acetyl-coa acetyltransferase
DSM104443_RS03870	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DSM104443_RS03890	ENOG4108M3P	Membrane
DSM104443_RS03895	ENOG4105D0M	Protease HtpX homolog
DSM104443_RS03900	ENOG4108IQE	Amp-dependent synthetase and ligase
DSM104443_RS03910	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
DSM104443_RS03920	ENOG4105NAU	thioesterase Superfamily protein
DSM104443_RS03935	ENOG4105CHU	acetyl-coa acetyltransferase
DSM104443_RS03945	ENOG4105D25	secreted protein
DSM104443_RS03960	ENOG4105M08	Membrane
DSM104443_RS03970	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
DSM104443_RS03975	ENOG4105QVC	MOSC domain-containing protein
DSM104443_RS04000	ENOG410829K	Lysine exporter protein (Lyse ygga)
DSM104443_RS04005	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
DSM104443_RS04010	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
DSM104443_RS04070	ENOG4105T38	integral membrane protein
DSM104443_RS04080	ENOG4105CKU	formyltetrahydrofolate synthetase
DSM104443_RS04090	ENOG4105D9P	serine threonine protein kinase
DSM104443_RS04100	ENOG4105BZU	Histidine kinase
DSM104443_RS04105	ENOG4105BZU	Histidine kinase
DSM104443_RS04115	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DSM104443_RS04120	ENOG4105CQB	FAD linked oxidase domain protein
DSM104443_RS04125	ENOG4105CQB	FAD linked oxidase domain protein
DSM104443_RS04130	ENOG4105EU8	FAD linked oxidase domain protein
DSM104443_RS04135	ENOG4108K3A	Glutathione S-transferase
DSM104443_RS04140	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
DSM104443_RS04150	ENOG4105NRA	50s ribosomal protein l31 type b
DSM104443_RS04155	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
DSM104443_RS04160	ENOG4105K63	Thioredoxin
DSM104443_RS04165	ENOG4108Z4U	Ferredoxin
DSM104443_RS04175	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
DSM104443_RS04180	ENOG4105C4M	(Ubiquinol oxidase) subunit I
DSM104443_RS04190	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
DSM104443_RS04210	ENOG4108M9J	MaoC like domain protein
DSM104443_RS04225	ENOG4108YXG	UPF0502 protein
DSM104443_RS04235	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
DSM104443_RS04250	ENOG4105ETT	transcriptional Regulator, LysR family
DSM104443_RS04255	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
DSM104443_RS04260	ENOG4105BZS	acriflavin resistance protein
DSM104443_RS04275	ENOG4105E27	serine threonine protein kinase
DSM104443_RS04315	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
DSM104443_RS04325	ENOG4105W5Q	DNA repair protein (RadC
DSM104443_RS04330	ENOG4105KDC	50s ribosomal protein l28
DSM104443_RS04335	ENOG4105W0E	50S ribosomal protein L33
DSM104443_RS04355	ENOG4105EGS	Mechanosensitive ion channel
DSM104443_RS04375	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
DSM104443_RS04380	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
DSM104443_RS04400	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
DSM104443_RS04405	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
DSM104443_RS04415	ENOG4105DJ0	Poly(A) Polymerase
DSM104443_RS04420	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DSM104443_RS04460	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
DSM104443_RS04465	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
DSM104443_RS04475	ENOG4105VAW	lrga family
DSM104443_RS04505	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
DSM104443_RS04510	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
DSM104443_RS04530	ENOG4105D05	Receptor
DSM104443_RS04555	ENOG4105E39	Enoyl-CoA hydratase
DSM104443_RS04565	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DSM104443_RS04575	ENOG4105CI0	Citrate lyase
DSM104443_RS04585	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
DSM104443_RS04600	ENOG4105G2U	Cupin 2, conserved barrel domain protein
DSM104443_RS04620	ENOG4107T6J	Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit
DSM104443_RS04635	ENOG4105DY2	Paraquat-inducible protein b
DSM104443_RS04640	ENOG4105F1S	paraquat-inducible protein a
DSM104443_RS04660	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
DSM104443_RS04690	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
DSM104443_RS04695	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
DSM104443_RS04700	ENOG4108IFG	nitrite reductase, (NAD(P)H)
DSM104443_RS04705	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DSM104443_RS04715	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
DSM104443_RS04720	ENOG4105D7T	ABC transporter
DSM104443_RS04730	ENOG4105I5W	Transporter
DSM104443_RS04745	ENOG4108JJA	ABC, transporter
DSM104443_RS04750	ENOG4108JJA	ABC, transporter
DSM104443_RS04825	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
DSM104443_RS04840	ENOG4105ETT	transcriptional Regulator, LysR family
DSM104443_RS04855	ENOG4105F0N	pyrophosphate phospho-hydrolase
DSM104443_RS04865	ENOG4108Q5Y	Membrane
DSM104443_RS04870	ENOG41082BV	acetyltransferase
DSM104443_RS04875	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
DSM104443_RS04885	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
DSM104443_RS04890	ENOG4108V3W	Chemotaxis protein, CheW
DSM104443_RS04910	ENOG4105CJZ	response regulator
DSM104443_RS04940	ENOG4107TF3	peptidylprolyl cis-trans isomerase
DSM104443_RS04950	ENOG4105K9H	YciI-like protein
DSM104443_RS04955	ENOG4107835	probably involved in intracellular septation (By similarity)
DSM104443_RS04965	ENOG4105DB7	PHP domain protein
DSM104443_RS04970	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
DSM104443_RS04975	ENOG4107XZ0	Peptidase M50
DSM104443_RS04980	ENOG4105C31	Tryptophanyl-tRNA synthetase
DSM104443_RS04990	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
DSM104443_RS04995	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
DSM104443_RS05000	ENOG4105FE9	pseudouridine synthase
DSM104443_RS05015	ENOG4105ETT	transcriptional Regulator, LysR family
DSM104443_RS05030	ENOG4108W2Y	isochorismatase
DSM104443_RS05045	ENOG4105ZXK	Dehydrogenase
DSM104443_RS05060	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
DSM104443_RS05065	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
DSM104443_RS05070	ENOG4105MP9	class II Aldolase
DSM104443_RS05105	ENOG4105CZX	twitching motility protein
DSM104443_RS05110	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
DSM104443_RS05125	ENOG4108KQJ	Type 11 methyltransferase
DSM104443_RS05140	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DSM104443_RS05150	ENOG4105E8R	UPF0173 metal-dependent hydrolase
DSM104443_RS05155	ENOG4105CH5	extracellular solute-binding protein, family 7
DSM104443_RS05175	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
DSM104443_RS05190	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
DSM104443_RS05195	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
DSM104443_RS05200	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
DSM104443_RS05205	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
DSM104443_RS05210	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DSM104443_RS05245	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
DSM104443_RS05250	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
DSM104443_RS05255	ENOG4105CE9	30S ribosomal protein S2
DSM104443_RS05260	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
DSM104443_RS05265	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DSM104443_RS05270	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
DSM104443_RS05275	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DSM104443_RS05280	ENOG4105KNE	Phosphatidate cytidylyltransferase
DSM104443_RS05285	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
DSM104443_RS05290	ENOG4105DZP	Membrane-associated zinc metalloprotease
DSM104443_RS05295	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSM104443_RS05305	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DSM104443_RS05310	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
DSM104443_RS05315	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DSM104443_RS05320	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DSM104443_RS05325	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DSM104443_RS05330	ENOG4105C2N	RNA methyltransferase TrmH family group 3
DSM104443_RS05340	ENOG4105D78	K07001 NTE family protein
DSM104443_RS05350	ENOG4108FHP	Autotransporter beta-domain
DSM104443_RS05355	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
DSM104443_RS05360	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
DSM104443_RS05365	ENOG4107YB6	acetyltransferase, (GNAT) family
DSM104443_RS05380	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DSM104443_RS05410	ENOG4105D9P	serine threonine protein kinase
DSM104443_RS05425	ENOG4105EPD	Oligopeptide transporter, Opt family
DSM104443_RS05475	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DSM104443_RS05535	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS05545	ENOG4108JQ7	(ABC) transporter
DSM104443_RS05580	ENOG4105YVS	arsR family transcriptional regulator
DSM104443_RS05585	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DSM104443_RS05610	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DSM104443_RS05705	ENOG4107T0X	DNA ligase
DSM104443_RS05710	ENOG4107T0X	DNA ligase
DSM104443_RS05715	ENOG4107QHF	type ii secretion system protein e
DSM104443_RS05725	ENOG4105CUJ	penicillin amidase
DSM104443_RS05745	ENOG4107QRT	dEAD DEAH box helicase
DSM104443_RS05785	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DSM104443_RS05790	ENOG4108MN8	Membrane
DSM104443_RS05830	ENOG4105I4A	GCN5-related N-acetyltransferase
DSM104443_RS05845	ENOG4105E9Z	Nad-dependent epimerase dehydratase
DSM104443_RS05850	ENOG4105JXH	GntR family transcriptional regulator
DSM104443_RS05855	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
DSM104443_RS05875	ENOG4105CFH	Aspartokinase
DSM104443_RS05885	ENOG41066T0	asmA family
DSM104443_RS05895	ENOG4105DFP	Integrase
DSM104443_RS05970	ENOG4105EHU	Circadian clock protein KaiC
DSM104443_RS05975	ENOG4105BZU	Histidine kinase
DSM104443_RS06015	ENOG4108IXY	short-chain dehydrogenase reductase
DSM104443_RS06025	ENOG4108KGA	Nitrile hydratase
DSM104443_RS06030	ENOG4105EKJ	Nitrile hydratase subunit alpha
DSM104443_RS06040	ENOG4108SVW	integral membrane protein
DSM104443_RS06045	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
DSM104443_RS06050	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DSM104443_RS06060	ENOG4105BZU	Histidine kinase
DSM104443_RS06075	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
DSM104443_RS06085	ENOG4105CHR	reductase
DSM104443_RS06095	ENOG4105C32	Amino acid ABC transporter (Permease)
DSM104443_RS06105	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DSM104443_RS06110	ENOG4105D7K	pfkb domain protein
DSM104443_RS06120	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
DSM104443_RS06125	ENOG4108IUZ	ABC transporter
DSM104443_RS06130	ENOG4108IV0	ABC, transporter
DSM104443_RS06135	ENOG4108IJ6	ABC transporter
DSM104443_RS06170	ENOG4108T5G	Adenylate
DSM104443_RS06200	ENOG4105IPI	Membrane
DSM104443_RS06225	ENOG4105C26	Dehydrogenase
DSM104443_RS06245	ENOG4105C0A	alcohol dehydrogenase
DSM104443_RS06260	ENOG4105CPN	adenine deaminase
DSM104443_RS06280	ENOG4105EAM	Na Pi-cotransporter
DSM104443_RS06315	ENOG4108JQ6	ABC transporter
DSM104443_RS06320	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS06340	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
DSM104443_RS06360	ENOG4105C4Y	ABC transporter
DSM104443_RS06370	ENOG4107RCV	ABC transporter, permease
DSM104443_RS06420	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DSM104443_RS06425	ENOG4105GJM	(LipO)protein
DSM104443_RS06430	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
DSM104443_RS06445	ENOG4105EZE	Cupin 4 family protein
DSM104443_RS06450	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104443_RS06455	ENOG4108YZY	peptidylprolyl cis-trans isomerase
DSM104443_RS06465	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
DSM104443_RS06485	ENOG4109066	lysm domain bon superfamily protein
DSM104443_RS06490	ENOG4105CEP	NADH dehydrogenase
DSM104443_RS06510	ENOG4105ECY	inositol monophosphatase
DSM104443_RS06525	ENOG4105D7W	serine acetyltransferase
DSM104443_RS06535	ENOG4105C3J	Cysteine desulfurase
DSM104443_RS06540	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
DSM104443_RS06545	ENOG4108Z4V	iron-sulfur cluster assembly
DSM104443_RS06550	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
DSM104443_RS06560	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
DSM104443_RS06565	ENOG4108ZIT	Ferredoxin, 2FE-2S
DSM104443_RS06570	ENOG4105WVQ	Fe-S assembly protein IscX
DSM104443_RS06585	ENOG4105DKB	L-sorbosone dehydrogenase
DSM104443_RS06590	ENOG4105N7H	Cytochrome
DSM104443_RS06595	ENOG4105CHB	tonB-dependent Receptor
DSM104443_RS06600	ENOG410870F	Cyclic nucleotide-binding protein
DSM104443_RS06605	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DSM104443_RS06615	ENOG4107WP9	Histidine kinase
DSM104443_RS06625	ENOG4105EAC	phosphoserine phosphatase
DSM104443_RS06630	ENOG4108JA2	transcriptioN-repair coupling factor
DSM104443_RS06635	ENOG4107GFK	fumarate
DSM104443_RS06640	ENOG4108TEB	UPF0114 protein
DSM104443_RS06655	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DSM104443_RS06665	ENOG4105BZU	Histidine kinase
DSM104443_RS06670	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DSM104443_RS06695	ENOG4107QN1	sodium solute
DSM104443_RS06735	ENOG4105C7K	acetolactate synthase
DSM104443_RS06740	ENOG4108ZP8	Acetolactate synthase small subunit
DSM104443_RS06745	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
DSM104443_RS06750	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
DSM104443_RS06755	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
DSM104443_RS06760	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DSM104443_RS06770	ENOG4105CV8	reductase
DSM104443_RS06780	ENOG4107QTF	adenylosuccinate lyase
DSM104443_RS06785	ENOG4108U78	Glutathione S-transferase
DSM104443_RS06790	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
DSM104443_RS06800	ENOG4108R99	pseudouridine synthase
DSM104443_RS06810	ENOG4105VEQ	Cold shock protein
DSM104443_RS06815	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
DSM104443_RS06820	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DSM104443_RS06830	ENOG4107S7U	Sulfide dehydrogenase
DSM104443_RS06835	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
DSM104443_RS06840	ENOG4105D9U	N-acetyltransferase
DSM104443_RS06845	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
DSM104443_RS06850	ENOG4105D7A	ATP-binding protein
DSM104443_RS06855	ENOG4105CDY	transcriptional regulatory protein
DSM104443_RS06860	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
DSM104443_RS06865	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
DSM104443_RS06870	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
DSM104443_RS06875	ENOG4107YD3	Thioesterase
DSM104443_RS06880	ENOG4105E02	MotA TolQ exbB proton channel
DSM104443_RS06885	ENOG4105M8F	Biopolymer transport protein exbD tolR
DSM104443_RS06895	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
DSM104443_RS06900	ENOG4105KCK	Peptidoglycan-associated lipoprotein
DSM104443_RS06905	ENOG4105UFD	tol-pal system protein YbgF
DSM104443_RS06910	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
DSM104443_RS06935	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
DSM104443_RS06940	ENOG4107TCE	N-acetyltransferase
DSM104443_RS06945	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
DSM104443_RS06950	ENOG4105JJR	Histidine kinase
DSM104443_RS06960	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
DSM104443_RS06965	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
DSM104443_RS06970	ENOG4105CHV	Transcription elongation factor NusA
DSM104443_RS06975	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DSM104443_RS06980	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
DSM104443_RS06985	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DSM104443_RS06990	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
DSM104443_RS06995	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DSM104443_RS07020	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
DSM104443_RS07025	ENOG4105VDB	UPF0125 protein
DSM104443_RS07050	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DSM104443_RS07055	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DSM104443_RS07085	ENOG4105KUZ	arsenate reductase
DSM104443_RS07090	ENOG4108Z6B	deaminase
DSM104443_RS07095	ENOG4105C0B	DNA polymerase III (alpha subunit)
DSM104443_RS07100	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
DSM104443_RS07110	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DSM104443_RS07120	ENOG4105DHP	deoxycytidine triphosphate deaminase
DSM104443_RS07125	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DSM104443_RS07165	ENOG4105VZ8	Transcriptional regulator
DSM104443_RS07190	ENOG4105FC8	fad dependent oxidoreductase
DSM104443_RS07195	ENOG4107QK9	Beta-lactamase
DSM104443_RS07200	ENOG4105DUX	Transporter
DSM104443_RS07210	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
DSM104443_RS07235	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
DSM104443_RS07240	ENOG4105NBF	ammecr1 domain protein
DSM104443_RS07255	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DSM104443_RS07260	ENOG41090A4	Pterin carbinolamine dehydratase
DSM104443_RS07265	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
DSM104443_RS07270	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
DSM104443_RS07275	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
DSM104443_RS07295	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS07310	ENOG4107TH8	cina domain protein
DSM104443_RS07315	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
DSM104443_RS07320	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
DSM104443_RS07325	ENOG4108004	Modulates RecA activity (By similarity)
DSM104443_RS07335	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DSM104443_RS07345	ENOG4105CPK	Glycosyl transferase (Group 1
DSM104443_RS07350	ENOG4105E09	nadh pyrophosphatase
DSM104443_RS07360	ENOG4105DA5	(ABC) transporter
DSM104443_RS07370	ENOG4107QN2	dihydrolipoyl dehydrogenase
DSM104443_RS07375	ENOG4107QSN	dihydrolipoamide acetyltransferase
DSM104443_RS07380	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
DSM104443_RS07385	ENOG4108ZF3	Phosphatase
DSM104443_RS07400	ENOG4107QHF	type ii secretion system protein e
DSM104443_RS07405	ENOG4105DHT	Metal Dependent Phosphohydrolase
DSM104443_RS07410	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
DSM104443_RS07415	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
DSM104443_RS07440	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
DSM104443_RS07450	ENOG4105ERG	peptidase m48, ste24p
DSM104443_RS07455	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DSM104443_RS07470	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
DSM104443_RS07475	ENOG4105CHR	reductase
DSM104443_RS07490	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DSM104443_RS07505	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
DSM104443_RS07540	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
DSM104443_RS07550	ENOG41067HS	methyltransferase
DSM104443_RS07560	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
DSM104443_RS07575	ENOG4107QMP	dna polymerase iii subunits gamma and tau
DSM104443_RS07585	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
DSM104443_RS07625	ENOG4105GVR	general secretion pathway protein D
DSM104443_RS07630	ENOG4108UHE	carbonic anhydrase
DSM104443_RS07635	ENOG4107SM8	Adenylate Guanylate cyclase
DSM104443_RS07680	ENOG4108V5V	Serine Threonine protein kinase
DSM104443_RS07690	ENOG4107QPK	)-transporter
DSM104443_RS07700	ENOG4105CK2	sodium dicarboxylate symporter
DSM104443_RS07710	ENOG4108ZXC	Two component transcriptional regulator, luxr family
DSM104443_RS07715	ENOG4105BZU	Histidine kinase
DSM104443_RS07720	ENOG4105BZU	Histidine kinase
DSM104443_RS07725	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
DSM104443_RS07735	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
DSM104443_RS07755	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
DSM104443_RS07760	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
DSM104443_RS07765	ENOG4107S1E	Beta-lactamase
DSM104443_RS07770	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
DSM104443_RS07775	ENOG4108J59	Extracellular solute-binding protein, family 5
DSM104443_RS07805	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
DSM104443_RS07815	ENOG4105C6K	Malic enzyme
DSM104443_RS07830	ENOG4107RIS	Acyl-transferase
DSM104443_RS07870	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
DSM104443_RS07895	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
DSM104443_RS07920	ENOG41082BM	Transcriptional regulator, arsr family
DSM104443_RS07935	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DSM104443_RS07950	ENOG4105E7U	AraC family transcriptional regulator
DSM104443_RS07955	ENOG4105C9K	Endothelin-converting enzyme 1
DSM104443_RS07965	ENOG4108JQ1	Dehydrogenase
DSM104443_RS07975	ENOG4105CW7	secretion protein, HlyD family
DSM104443_RS07980	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DSM104443_RS07985	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DSM104443_RS07990	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DSM104443_RS07995	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
DSM104443_RS08005	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
DSM104443_RS08010	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
DSM104443_RS08015	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DSM104443_RS08020	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
DSM104443_RS08025	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
DSM104443_RS08030	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
DSM104443_RS08040	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
DSM104443_RS08045	ENOG4105C28	cystathionine
DSM104443_RS08065	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
DSM104443_RS08075	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
DSM104443_RS08090	ENOG4105C8N	cysteinyl-tRNA synthetase
DSM104443_RS08100	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DSM104443_RS08105	ENOG4105CFG	Acts as a chaperone (By similarity)
DSM104443_RS08110	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DSM104443_RS08115	ENOG41086DT	Membrane protein of unknown function
DSM104443_RS08120	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
DSM104443_RS08125	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
DSM104443_RS08130	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
DSM104443_RS08135	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
DSM104443_RS08150	ENOG4106CJB	Phospholipase Carboxylesterase
DSM104443_RS08155	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
DSM104443_RS08160	ENOG4105N42	UPF0307 protein
DSM104443_RS08165	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
DSM104443_RS08170	ENOG4105CH5	extracellular solute-binding protein, family 7
DSM104443_RS08180	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
DSM104443_RS08185	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104443_RS08205	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DSM104443_RS08210	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
DSM104443_RS08215	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
DSM104443_RS08235	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
DSM104443_RS08240	ENOG4107YIM	Involved in the transcription termination process (By similarity)
DSM104443_RS08245	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
DSM104443_RS08250	ENOG4108ZAI	phosphatidylglycerophosphatase a
DSM104443_RS08255	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
DSM104443_RS08275	ENOG4107QN2	dihydrolipoyl dehydrogenase
DSM104443_RS08280	ENOG4105EHV	domain protein
DSM104443_RS08285	ENOG4105C5Q	Transcriptional regulator
DSM104443_RS08290	ENOG41064MX	Tetr family transcriptional regulator
DSM104443_RS08310	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
DSM104443_RS08315	ENOG4108RAC	Rubrerythrin
DSM104443_RS08340	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DSM104443_RS08355	ENOG4105CGP	Urocanate hydratase
DSM104443_RS08395	ENOG4105C3F	Signal peptidase i
DSM104443_RS08400	ENOG4107QPD	alcohol dehydrogenase
DSM104443_RS08415	ENOG4105C4W	S-formylglutathione hydrolase
DSM104443_RS08425	ENOG41061CK	Antibiotic biosynthesis monooxygenase
DSM104443_RS08435	ENOG4108J2R	molybdopterin oxidoreductase
DSM104443_RS08450	ENOG4105R40	Glycine betaine carnitine choline
DSM104443_RS08460	ENOG4106517	Short-chain dehydrogenase reductase Sdr
DSM104443_RS08465	ENOG4105C01	Dihydroxy-acid dehydratase
DSM104443_RS08485	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
DSM104443_RS08490	ENOG4105EG2	ABC transporter, permease
DSM104443_RS08510	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DSM104443_RS08525	ENOG4105C8Q	Methyl-accepting chemotaxis
DSM104443_RS08530	ENOG4105C5I	Dehydrogenase
DSM104443_RS08535	ENOG4105DG4	malate L-lactate dehydrogenase
DSM104443_RS08545	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
DSM104443_RS08560	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
DSM104443_RS08565	ENOG4105CTX	dehydratase
DSM104443_RS08570	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
DSM104443_RS08585	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DSM104443_RS08590	ENOG4108J2P	Alpha beta hydrolase fold
DSM104443_RS08610	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
DSM104443_RS08630	ENOG4105E4C	Lytic transglycosylase catalytic
DSM104443_RS08635	ENOG4105BZS	acriflavin resistance protein
DSM104443_RS08640	ENOG410624X	efflux transporter, rnd family, mfp subunit
DSM104443_RS08660	ENOG41080XP	Cbs domain
DSM104443_RS08665	ENOG4105DEN	Luciferase family
DSM104443_RS08670	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DSM104443_RS08675	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DSM104443_RS08685	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
DSM104443_RS08690	ENOG4105BZU	Histidine kinase
DSM104443_RS08700	ENOG4107XI7	Tetr family transcriptional regulator
DSM104443_RS08705	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
DSM104443_RS08715	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
DSM104443_RS08780	ENOG4107E2E	PKHD-type hydroxylase
DSM104443_RS08795	ENOG4105BZU	Histidine kinase
DSM104443_RS08800	ENOG4105BZU	Histidine kinase
DSM104443_RS08815	ENOG4105BZU	Histidine kinase
DSM104443_RS08825	ENOG4105D05	Receptor
DSM104443_RS08830	ENOG4105ES5	Histidine kinase
DSM104443_RS08835	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DSM104443_RS08850	ENOG4108WZ2	response regulator
DSM104443_RS08865	ENOG4105C8Q	Methyl-accepting chemotaxis
DSM104443_RS08870	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DSM104443_RS08895	ENOG4105C2M	dna polymerase I
DSM104443_RS08905	ENOG4108KU3	Integrase
DSM104443_RS08990	ENOG4105H1G	trap transporter solute receptor taxi family
DSM104443_RS08995	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DSM104443_RS09025	ENOG4105DZQ	phospholipase D Transphosphatidylase
DSM104443_RS09075	ENOG4105BZU	Histidine kinase
DSM104443_RS09125	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
DSM104443_RS09155	ENOG4106UX7	integral membrane protein
DSM104443_RS09180	ENOG4108WQI	RNA Polymerase
DSM104443_RS09200	ENOG4107GRR	phosphate transport regulator
DSM104443_RS09205	ENOG4107QXV	Phosphate transporter
DSM104443_RS09225	ENOG4105C7F	AcnD-accessory protein PrpF
DSM104443_RS09230	ENOG4107QM5	aconitate hydratase
DSM104443_RS09255	ENOG4107QM5	aconitate hydratase
DSM104443_RS09270	ENOG4107QM5	aconitate hydratase
DSM104443_RS09280	ENOG4105DXD	2-methylcitrate dehydratase
DSM104443_RS09290	ENOG4105BZN	citrate synthase
DSM104443_RS09295	ENOG4105CR4	methylisocitrate lyase
DSM104443_RS09305	ENOG4105DJG	MaoC domain protein dehydratase
DSM104443_RS09310	ENOG4105CI0	Citrate lyase
DSM104443_RS09315	ENOG4105FDP	GntR family transcriptional regulator
DSM104443_RS09325	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
DSM104443_RS09335	ENOG4105E33	succinate dehydrogenase
DSM104443_RS09340	ENOG41060IS	Flavinator of succinate dehydrogenase
DSM104443_RS09345	ENOG4105BZN	citrate synthase
DSM104443_RS09350	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
DSM104443_RS09355	ENOG4105C7S	Dehydrogenase
DSM104443_RS09375	ENOG4107QN2	dihydrolipoyl dehydrogenase
DSM104443_RS09380	ENOG4105D6Z	AFG1 family ATPase
DSM104443_RS09385	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
DSM104443_RS09395	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DSM104443_RS09405	ENOG4105CRQ	synthase (Component I)
DSM104443_RS09415	ENOG4105CEY	Amp-dependent synthetase and ligase
DSM104443_RS09430	ENOG4105E39	Enoyl-CoA hydratase
DSM104443_RS09445	ENOG4105C0Z	ABC transporter
DSM104443_RS09450	ENOG4108IV0	ABC, transporter
DSM104443_RS09460	ENOG4105C32	Amino acid ABC transporter (Permease)
DSM104443_RS09475	ENOG4105CDH	Citrulline--aspartate ligase
DSM104443_RS09495	ENOG4105BZJ	Electron transfer flavoprotein
DSM104443_RS09500	ENOG4105C10	Electron transfer flavoprotein
DSM104443_RS09505	ENOG4105CSU	acyl-Coa dehydrogenase
DSM104443_RS09510	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
DSM104443_RS09520	ENOG4105D8V	Glucose sorbosone dehydrogenase
DSM104443_RS09525	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
DSM104443_RS09545	ENOG4105BZU	Histidine kinase
DSM104443_RS09550	ENOG4105ERH	Fumarylacetoacetate hydrolase
DSM104443_RS09555	ENOG4105CGU	Enoyl-CoA hydratase
DSM104443_RS09560	ENOG4105E39	Enoyl-CoA hydratase
DSM104443_RS09565	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DSM104443_RS09570	ENOG4105C26	Dehydrogenase
DSM104443_RS09575	ENOG4105D0C	transport protein
DSM104443_RS09620	ENOG4105CBG	Sulfatase
DSM104443_RS09640	ENOG4108ZXC	Two component transcriptional regulator, luxr family
DSM104443_RS09645	ENOG4105BZU	Histidine kinase
DSM104443_RS09710	ENOG4105E39	Enoyl-CoA hydratase
DSM104443_RS09715	ENOG4107QX3	carboxylase
DSM104443_RS09730	ENOG4105C1G	acyl-Coa dehydrogenase
DSM104443_RS09745	ENOG4105CHU	acetyl-coa acetyltransferase
DSM104443_RS09755	ENOG4105C1G	acyl-Coa dehydrogenase
DSM104443_RS09770	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DSM104443_RS09780	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DSM104443_RS09785	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DSM104443_RS09795	ENOG4105ETT	transcriptional Regulator, LysR family
DSM104443_RS09800	ENOG4105KHM	amidohydrolase 2
DSM104443_RS09805	ENOG4105JSC	dimethylmenaquinone methyltransferase
DSM104443_RS09820	ENOG4108IQE	Amp-dependent synthetase and ligase
DSM104443_RS09825	ENOG4105C0Z	ABC transporter
DSM104443_RS09830	ENOG4105C32	Amino acid ABC transporter (Permease)
DSM104443_RS09845	ENOG4108IV0	ABC, transporter
DSM104443_RS09855	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DSM104443_RS09860	ENOG4107QKW	extracellular solute-binding protein family 1
DSM104443_RS09880	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
DSM104443_RS09900	ENOG4108IUW	ABC transporter
DSM104443_RS09905	ENOG4108SDH	ABC, transporter
DSM104443_RS09910	ENOG4105DVT	helicase
DSM104443_RS09935	ENOG4105E0F	Histidine kinase
DSM104443_RS09960	ENOG41072GX	Peptidase M22 Glycoprotease
DSM104443_RS09970	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
DSM104443_RS09990	ENOG4107258	Transcriptional regulator
DSM104443_RS09995	ENOG4105KWW	Biogenesis protein
DSM104443_RS10000	ENOG4107QX9	Thiol disulfide interChange protein
DSM104443_RS10005	ENOG4105DA4	cytochrome c-type biogenesis protein
DSM104443_RS10010	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
DSM104443_RS10020	ENOG41060IM	Heme exporter protein
DSM104443_RS10025	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
DSM104443_RS10030	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
DSM104443_RS10070	ENOG4105CAY	ferredoxin--nadp reductase
DSM104443_RS10080	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
DSM104443_RS10085	ENOG4105BZU	Histidine kinase
DSM104443_RS10090	ENOG4105CPI	Metal Dependent Phosphohydrolase
DSM104443_RS10125	ENOG4105CBS	Chea signal transduction histidine kinase
DSM104443_RS10130	ENOG4105C8Q	Methyl-accepting chemotaxis
DSM104443_RS10135	ENOG4105C8Q	Methyl-accepting chemotaxis
DSM104443_RS10140	ENOG4108V3W	Chemotaxis protein, CheW
DSM104443_RS10145	ENOG4105C8Q	Methyl-accepting chemotaxis
DSM104443_RS10150	ENOG4105BZU	Histidine kinase
DSM104443_RS10155	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
DSM104443_RS10165	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
DSM104443_RS10170	ENOG4105DQU	oxidoreductase, subunit beta
DSM104443_RS10185	ENOG4105C5W	Aldolase
DSM104443_RS10200	ENOG4108IAB	Phoh family
DSM104443_RS10205	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104443_RS10235	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DSM104443_RS10250	ENOG4108Z18	K06886 hemoglobin
DSM104443_RS10255	ENOG4105CI3	gtp-binding protein typa
DSM104443_RS10260	ENOG4105BZU	Histidine kinase
DSM104443_RS10295	ENOG4108J2P	Alpha beta hydrolase fold
DSM104443_RS10305	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
DSM104443_RS10310	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DSM104443_RS10325	ENOG4105NBR	Pectinesterase
DSM104443_RS10335	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
DSM104443_RS10345	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
DSM104443_RS10355	ENOG4105E9Z	Nad-dependent epimerase dehydratase
DSM104443_RS10360	ENOG4105ETE	Transcriptional regulator (LacI family
DSM104443_RS10365	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
DSM104443_RS10370	ENOG4105M00	molybdopterin converting factor, subunit 1
DSM104443_RS10375	ENOG4108ZAF	Molybdopterin
DSM104443_RS10380	ENOG41080HT	Transcriptional regulator, arsr family
DSM104443_RS10385	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
DSM104443_RS10390	ENOG4105W2Z	cytochrome C, class I
DSM104443_RS10420	ENOG4105CGH	5'-nucleotidase
DSM104443_RS10435	ENOG4105N7H	Cytochrome
DSM104443_RS10440	ENOG4105DKB	L-sorbosone dehydrogenase
DSM104443_RS10475	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DSM104443_RS10480	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DSM104443_RS10490	ENOG4108JJA	ABC, transporter
DSM104443_RS10520	ENOG4105MHT	Transcriptional regulator, ARSR family
DSM104443_RS10525	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
DSM104443_RS10540	ENOG4105C0B	DNA polymerase III (alpha subunit)
DSM104443_RS10555	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
DSM104443_RS10575	ENOG4105D05	Receptor
DSM104443_RS10590	ENOG4105CP9	extracellular ligand-binding receptor
DSM104443_RS10610	ENOG410667J	hydrolase
DSM104443_RS10620	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
DSM104443_RS10625	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
DSM104443_RS10630	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
DSM104443_RS10650	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
DSM104443_RS10670	ENOG4105DQE	DNA ligase
DSM104443_RS10690	ENOG4105BZU	Histidine kinase
DSM104443_RS10695	ENOG4107Z5C	methylesterase
DSM104443_RS10700	ENOG4105BZU	Histidine kinase
DSM104443_RS10705	ENOG4105BZU	Histidine kinase
DSM104443_RS10720	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DSM104443_RS10725	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DSM104443_RS10730	ENOG4105FDF	Could be involved in DNA repair (By similarity)
DSM104443_RS10735	ENOG4105DQE	DNA ligase
DSM104443_RS10740	ENOG4105VDW	Csbd family
DSM104443_RS10775	ENOG4105DS1	cytochrome b561
DSM104443_RS10785	ENOG4108YYC	ycei family
DSM104443_RS10800	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
DSM104443_RS10815	ENOG4105W53	bacterioferritin-associated ferredoxin
DSM104443_RS10820	ENOG4105WQ5	TonB family
DSM104443_RS10825	ENOG4107SJW	iron permease, FTR1
DSM104443_RS10830	ENOG4108ESX	Receptor
DSM104443_RS10845	ENOG4108UQY	Iron-storage protein
DSM104443_RS10855	ENOG4105C1G	acyl-Coa dehydrogenase
DSM104443_RS10880	ENOG4105CEY	Amp-dependent synthetase and ligase
DSM104443_RS10885	ENOG4105D8K	carboxyl transferase
DSM104443_RS10890	ENOG4105CQB	FAD linked oxidase domain protein
DSM104443_RS10895	ENOG4105G3Z	GntR family transcriptional regulator
DSM104443_RS10900	ENOG4105C5R	Aminotransferase
DSM104443_RS10920	ENOG4107RGH	Aldehyde dehydrogenase
DSM104443_RS10935	ENOG4105C8Y	Acetylornithine aminotransferase
DSM104443_RS10940	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
DSM104443_RS10950	ENOG4105CEY	Amp-dependent synthetase and ligase
DSM104443_RS10995	ENOG41062JF	Transcriptional regulator
DSM104443_RS11005	ENOG4105PDP	Short chain dehydrogenase
DSM104443_RS11010	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104443_RS11025	ENOG4108JQ1	Dehydrogenase
DSM104443_RS11030	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
DSM104443_RS11040	ENOG4105F8V	Hydrolase, tatD family
DSM104443_RS11045	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
DSM104443_RS11055	ENOG4107QRG	dna polymerase iii
DSM104443_RS11060	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DSM104443_RS11065	ENOG4105HHA	aminodeoxychorismate lyase
DSM104443_RS11070	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
DSM104443_RS11075	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DSM104443_RS11080	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DSM104443_RS11085	ENOG4105CHR	reductase
DSM104443_RS11090	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
DSM104443_RS11095	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DSM104443_RS11100	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
DSM104443_RS11105	ENOG4105VGS	50s ribosomal protein l32
DSM104443_RS11115	ENOG4108UHJ	MAF-like protein
DSM104443_RS11120	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
DSM104443_RS11125	ENOG4105BZU	Histidine kinase
DSM104443_RS11140	ENOG4107XGZ	Hydrolase
DSM104443_RS11145	ENOG4105EI2	Pseudouridine synthase
DSM104443_RS11150	ENOG4105C03	ribonuclease
DSM104443_RS11165	ENOG4105CNA	YD repeat protein
DSM104443_RS11185	ENOG4105KJF	protein tyrosine phosphatase
DSM104443_RS11195	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
DSM104443_RS11245	ENOG4107R1I	NAD-dependent malic enzyme
DSM104443_RS11250	ENOG4105EYW	Ion transport protein
DSM104443_RS11265	ENOG4108XG2	Histidine kinase
DSM104443_RS11270	ENOG4105WH1	Two component transcriptional regulator luxr family
DSM104443_RS11275	ENOG4105BZU	Histidine kinase
DSM104443_RS11280	ENOG4108UXN	response regulator
DSM104443_RS11285	ENOG4105BZU	Histidine kinase
DSM104443_RS11300	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
DSM104443_RS11305	ENOG4105BZU	Histidine kinase
DSM104443_RS11310	ENOG4105BZU	Histidine kinase
DSM104443_RS11330	ENOG41077A9	carbonic anhydrase
DSM104443_RS11345	ENOG4107SET	aldo keto reductase
DSM104443_RS11355	ENOG4108HWW	ABC transporter
DSM104443_RS11360	ENOG4105DFW	ABC transporter
DSM104443_RS11365	ENOG4105C93	Xylose Isomerase
DSM104443_RS11370	ENOG4105C93	Xylose Isomerase
DSM104443_RS11375	ENOG4105CMG	Carbohydrate kinase
DSM104443_RS11385	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
DSM104443_RS11390	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
DSM104443_RS11410	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
DSM104443_RS11415	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
DSM104443_RS11565	ENOG4105DSG	hydrolase family 43
DSM104443_RS11610	ENOG4105EFX	secretion protein, HlyD family
DSM104443_RS11615	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
DSM104443_RS11635	ENOG4105DG4	malate L-lactate dehydrogenase
DSM104443_RS11645	ENOG4108NNI	Beta-lactamase domain-containing protein
DSM104443_RS11665	ENOG4105FE9	pseudouridine synthase
DSM104443_RS11675	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DSM104443_RS11690	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS11695	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS11705	ENOG4108JQ7	(ABC) transporter
DSM104443_RS11720	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
DSM104443_RS11730	ENOG4105CEY	Amp-dependent synthetase and ligase
DSM104443_RS11735	ENOG4105IJJ	transcriptional regulator, crp fnr family
DSM104443_RS11785	ENOG4108KPJ	rna polymerase sigma factor
DSM104443_RS11795	ENOG4105WH1	Two component transcriptional regulator luxr family
DSM104443_RS11815	ENOG4105FFC	UPF0187 protein
DSM104443_RS11830	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DSM104443_RS11895	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DSM104443_RS11930	ENOG4105CIR	epoxide hydrolase
DSM104443_RS11940	ENOG4105WH1	Two component transcriptional regulator luxr family
DSM104443_RS11945	ENOG4105BZU	Histidine kinase
DSM104443_RS11950	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DSM104443_RS11965	ENOG4105CIR	epoxide hydrolase
DSM104443_RS11970	ENOG4105CIR	epoxide hydrolase
DSM104443_RS11980	ENOG4108ZXC	Two component transcriptional regulator, luxr family
DSM104443_RS11985	ENOG4108ZXC	Two component transcriptional regulator, luxr family
DSM104443_RS12015	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
DSM104443_RS12020	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
DSM104443_RS12025	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
DSM104443_RS12030	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
DSM104443_RS12035	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
DSM104443_RS12040	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
DSM104443_RS12045	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
DSM104443_RS12055	ENOG4105C3F	Signal peptidase i
DSM104443_RS12060	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
DSM104443_RS12070	ENOG4105C0H	protease
DSM104443_RS12085	ENOG4105EMN	RNA polymerase sigma factor
DSM104443_RS12090	ENOG4108IYU	L-aspartate oxidase
DSM104443_RS12095	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
DSM104443_RS12100	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
DSM104443_RS12115	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DSM104443_RS12130	ENOG4105EXC	Acyl-transferase
DSM104443_RS12135	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DSM104443_RS12150	ENOG4105E39	Enoyl-CoA hydratase
DSM104443_RS12155	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
DSM104443_RS12170	ENOG4107SWE	Methyltransferase
DSM104443_RS12185	ENOG4105BZU	Histidine kinase
DSM104443_RS12190	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
DSM104443_RS12245	ENOG4105KA0	thioesterase Superfamily protein
DSM104443_RS12250	ENOG4108ZHR	arsR family transcriptional regulator
DSM104443_RS12260	ENOG41069H0	dihydroorotase EC 3.5.2.3
DSM104443_RS12355	ENOG4105C08	Histidine kinase
DSM104443_RS12365	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
DSM104443_RS12380	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DSM104443_RS12385	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
DSM104443_RS12440	ENOG4105D6E	homoserine dehydrogenase
DSM104443_RS12450	ENOG4105CHM	Aminotransferase
DSM104443_RS12455	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DSM104443_RS12475	ENOG4105C7I	Dehydrogenase
DSM104443_RS12480	ENOG4107RP9	extracellular solute-binding protein, family 3
DSM104443_RS12485	ENOG4105EAD	ABC transporter
DSM104443_RS12490	ENOG4105DRP	amino acid AbC transporter
DSM104443_RS12495	ENOG4105CDA	abc transporter atp-binding protein
DSM104443_RS12515	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
DSM104443_RS12525	ENOG4105F8C	transglutaminase domain-containing protein
DSM104443_RS12530	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DSM104443_RS12540	ENOG4108K5P	(LipO)protein
DSM104443_RS12545	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
DSM104443_RS12550	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
DSM104443_RS12555	ENOG4105C9K	Endothelin-converting enzyme 1
DSM104443_RS12560	ENOG4105C9K	Endothelin-converting enzyme 1
DSM104443_RS12565	ENOG4105CHR	reductase
DSM104443_RS12575	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DSM104443_RS12580	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
DSM104443_RS12585	ENOG4105BZU	Histidine kinase
DSM104443_RS12590	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DSM104443_RS12595	ENOG4105CPQ	Dehydrogenase
DSM104443_RS12615	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
DSM104443_RS12620	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
DSM104443_RS12625	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
DSM104443_RS12630	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
DSM104443_RS12635	ENOG4105VJV	50s ribosomal protein L35
DSM104443_RS12640	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
DSM104443_RS12645	ENOG4105C22	threonyL-tRNA synthetase
DSM104443_RS12650	ENOG4105CAD	extracellular ligand-binding receptor
DSM104443_RS12655	ENOG4105GAK	amidohydrolase 2
DSM104443_RS12665	ENOG4105KHM	amidohydrolase 2
DSM104443_RS12675	ENOG4105DDW	LysR family Transcriptional regulator
DSM104443_RS12705	ENOG4108IV0	ABC, transporter
DSM104443_RS12710	ENOG4105C0Z	ABC transporter
DSM104443_RS12725	ENOG4105CAD	extracellular ligand-binding receptor
DSM104443_RS12730	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
DSM104443_RS12740	ENOG4107HP6	Transcriptional regulator
DSM104443_RS12745	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
DSM104443_RS12770	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
DSM104443_RS12775	ENOG4105C32	Amino acid ABC transporter (Permease)
DSM104443_RS12780	ENOG4105CNN	ABC, transporter
DSM104443_RS12785	ENOG4105C0Z	ABC transporter
DSM104443_RS12790	ENOG4108IV0	ABC, transporter
DSM104443_RS12795	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
DSM104443_RS12800	ENOG4108YZ9	Urea amidohydrolase subunit gamma
DSM104443_RS12810	ENOG4105CQM	Urea amidohydrolase subunit alpha
DSM104443_RS12815	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
DSM104443_RS12820	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
DSM104443_RS12825	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
DSM104443_RS12835	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
DSM104443_RS12845	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
DSM104443_RS12855	ENOG4108UVJ	appr-1-p processing domain protein
DSM104443_RS12870	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DSM104443_RS12905	ENOG4105GAK	amidohydrolase 2
DSM104443_RS12920	ENOG4108EC8	DNA internalization-related competence protein ComEC
DSM104443_RS12945	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DSM104443_RS12950	ENOG4105D60	lipoprotein releasing system transmembrane protein
DSM104443_RS12960	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
DSM104443_RS12985	ENOG4105CRK	lysyL-tRNA synthetase
DSM104443_RS12995	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
DSM104443_RS13000	ENOG4108NVM	synthesis repressor PhaR
DSM104443_RS13005	ENOG4105CHR	reductase
DSM104443_RS13010	ENOG4105CHR	reductase
DSM104443_RS13015	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
DSM104443_RS13025	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
DSM104443_RS13030	ENOG4105C34	Pseudouridine synthase
DSM104443_RS13035	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSM104443_RS13040	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
DSM104443_RS13045	ENOG4105C9X	ppx gppa phosphatase
DSM104443_RS13065	ENOG4105EV8	ectoine hydroxylase
DSM104443_RS13080	ENOG4107SFI	Major Facilitator superfamily
DSM104443_RS13085	ENOG4105CV6	ABC transporter, permease
DSM104443_RS13090	ENOG4108I0Y	(ABC) transporter
DSM104443_RS13095	ENOG4108UJV	acyl-CoA thioesterase i
DSM104443_RS13100	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
DSM104443_RS13105	ENOG4105D9P	serine threonine protein kinase
DSM104443_RS13115	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
DSM104443_RS13120	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
DSM104443_RS13125	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
DSM104443_RS13135	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
DSM104443_RS13140	ENOG4105D1H	recombination factor protein RarA
DSM104443_RS13145	ENOG4105DUM	transcriptional regulator, lysR family
DSM104443_RS13155	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
DSM104443_RS13160	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DSM104443_RS13165	ENOG4105C5R	Aminotransferase
DSM104443_RS13175	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
DSM104443_RS13180	ENOG4105CNU	cell division protein FtsK
DSM104443_RS13190	ENOG4105C3M	thioredoxin reductase
DSM104443_RS13195	ENOG4105C98	muts2 protein
DSM104443_RS13200	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
DSM104443_RS13205	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
DSM104443_RS13210	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DSM104443_RS13215	ENOG4105CKK	Glycosyl transferase, family 2
DSM104443_RS13220	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
DSM104443_RS13235	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
DSM104443_RS13245	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
DSM104443_RS13260	ENOG4108YZA	Nitrogen regulatory protein pii
DSM104443_RS13280	ENOG4105C6T	cysteine synthase
DSM104443_RS13285	ENOG4105KQC	Competence protein
DSM104443_RS13295	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
DSM104443_RS13300	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
DSM104443_RS13305	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
DSM104443_RS13310	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
DSM104443_RS13315	ENOG4105CFV	Tetratricopeptide repeat protein
DSM104443_RS13325	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
DSM104443_RS13330	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
DSM104443_RS13335	ENOG4105CAT	Cytidine monophosphate kinase
DSM104443_RS13340	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
DSM104443_RS13350	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DSM104443_RS13360	ENOG4108JQ1	Dehydrogenase
DSM104443_RS13365	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
DSM104443_RS13370	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DSM104443_RS13375	ENOG4105UYK	outer membrane protein a
DSM104443_RS13380	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
DSM104443_RS13385	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DSM104443_RS13390	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
DSM104443_RS13430	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DSM104443_RS13440	ENOG4107RGC	Glycosyl transferase, family 2
DSM104443_RS13445	ENOG4105F8J	Adenylate Guanylate cyclase
DSM104443_RS13450	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DSM104443_RS13465	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DSM104443_RS13490	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
DSM104443_RS13510	ENOG4105QAX	Iron-sulfur
DSM104443_RS13515	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DSM104443_RS13545	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DSM104443_RS13550	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
DSM104443_RS13555	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
DSM104443_RS13565	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DSM104443_RS13590	ENOG4107Z3H	Transcriptional regulator, TetR family
DSM104443_RS13595	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
DSM104443_RS13615	ENOG4107R11	Transcriptional regulator
DSM104443_RS13635	ENOG4105C11	sulfate adenylyltransferase), subunit 2
DSM104443_RS13645	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DSM104443_RS13650	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
DSM104443_RS13655	ENOG4108I5D	sulfate abc transporter
DSM104443_RS13665	ENOG4108IJ6	ABC transporter
DSM104443_RS13670	ENOG4105DP0	ferredoxin-NADP reductase
DSM104443_RS13680	ENOG4105D3R	alkyl hydroperoxide reductase
DSM104443_RS13685	ENOG4107R11	Transcriptional regulator
DSM104443_RS13695	ENOG4105GVF	(ABC) transporter
DSM104443_RS13700	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
DSM104443_RS13705	ENOG4105GVF	(ABC) transporter
DSM104443_RS13710	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS13735	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
DSM104443_RS13740	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
DSM104443_RS13745	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
DSM104443_RS13750	ENOG4105DCF	alanine dehydrogenase
DSM104443_RS13755	ENOG4108R3D	Electron transport complex
DSM104443_RS13760	ENOG4105CSM	endonuclease III
DSM104443_RS13775	ENOG41090Y2	cytochrome C
DSM104443_RS13790	ENOG4105BZU	Histidine kinase
DSM104443_RS13795	ENOG4107RZZ	dna polymerase iii epsilon subunit
DSM104443_RS13800	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DSM104443_RS13810	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DSM104443_RS13815	ENOG4105K5X	acetyltransferase
DSM104443_RS13820	ENOG4105CNF	WD-40 repeat protein
DSM104443_RS13840	ENOG4105E9H	Lytic Murein transglycosylase
DSM104443_RS13845	ENOG4105DGW	oligopeptidase A
DSM104443_RS13855	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS13865	ENOG4108EVY	peptide transport periplasmic protein
DSM104443_RS13870	ENOG4108EVY	peptide transport periplasmic protein
DSM104443_RS13880	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
DSM104443_RS13885	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
DSM104443_RS13905	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
DSM104443_RS13910	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
DSM104443_RS13915	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DSM104443_RS13920	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
DSM104443_RS13935	ENOG4105FE1	phytoene synthase
DSM104443_RS13940	ENOG4107S11	squalene-associated FAD-dependent desaturase
DSM104443_RS13960	ENOG4105D9P	serine threonine protein kinase
DSM104443_RS13965	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
DSM104443_RS13975	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DSM104443_RS13980	ENOG4105CDU	Replicative dna helicase
DSM104443_RS13985	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
DSM104443_RS13990	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
DSM104443_RS14000	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
DSM104443_RS14060	ENOG4108IAJ	Nad-dependent epimerase dehydratase
DSM104443_RS14095	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DSM104443_RS14115	ENOG4108RJ9	Glycosyl transferase, family 2
DSM104443_RS14150	ENOG4108I69	Glycosyl transferases group 1
DSM104443_RS14165	ENOG4107SET	aldo keto reductase
DSM104443_RS14170	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DSM104443_RS14175	ENOG4107YYJ	Glycosyl transferase, family 2
DSM104443_RS14185	ENOG4106WTF	Glycosyl transferase, family 2
DSM104443_RS14190	ENOG4105CMR	udp-glucose 4-epimerase
DSM104443_RS14200	ENOG4105C30	Nad-dependent epimerase dehydratase
DSM104443_RS14205	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
DSM104443_RS14210	ENOG4105ESV	Glycosyl transferase, family 4
DSM104443_RS14215	ENOG4105KJF	protein tyrosine phosphatase
DSM104443_RS14225	ENOG4105C2N	RNA methyltransferase TrmH family group 3
DSM104443_RS14230	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
DSM104443_RS14245	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
DSM104443_RS14250	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
DSM104443_RS14260	ENOG4105EPW	hflc protein
DSM104443_RS14265	ENOG4107QJR	hflk protein
DSM104443_RS14270	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DSM104443_RS14275	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
DSM104443_RS14280	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
DSM104443_RS14290	ENOG4105N21	Membrane
DSM104443_RS14295	ENOG4105CUT	histidyl-tRNA synthetase
DSM104443_RS14300	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
DSM104443_RS14305	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
DSM104443_RS14315	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DSM104443_RS14325	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
DSM104443_RS14330	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
DSM104443_RS14335	ENOG4108WBT	adenosyltransferase
DSM104443_RS14340	ENOG4108AEY	RNA polymerase sigma factor
DSM104443_RS14350	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
DSM104443_RS14360	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
DSM104443_RS14370	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
DSM104443_RS14375	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
DSM104443_RS14395	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
DSM104443_RS14415	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DSM104443_RS14430	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
DSM104443_RS14440	ENOG4105E0X	reductase
DSM104443_RS14445	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
DSM104443_RS14455	ENOG4105QD6	exported protein
DSM104443_RS14460	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
DSM104443_RS14470	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DSM104443_RS14480	ENOG4105XA0	heptosyltransferase ii
DSM104443_RS14565	ENOG4105GVR	general secretion pathway protein D
DSM104443_RS14570	ENOG4107QHF	type ii secretion system protein e
DSM104443_RS14575	ENOG4105D7Q	type ii secretion system
DSM104443_RS14580	ENOG4108VAU	general secretion pathway protein G
DSM104443_RS14585	ENOG4108VAU	general secretion pathway protein G
DSM104443_RS14590	ENOG4105X5Z	General secretion pathway protein I
DSM104443_RS14595	ENOG4108WWZ	General secretion pathway protein J
DSM104443_RS14600	ENOG4108RTD	type II secretion system protein K
DSM104443_RS14620	ENOG4105DNZ	Alpha Beta Hydrolase
DSM104443_RS14625	ENOG4107QKV	phosphomannomutase
DSM104443_RS14630	ENOG4105F8J	Adenylate Guanylate cyclase
DSM104443_RS14675	ENOG4108NST	exported protein
DSM104443_RS14690	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
DSM104443_RS14710	ENOG4105CE4	GlcNAc 6-P deacetylase
DSM104443_RS14715	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DSM104443_RS14720	ENOG4105FDP	GntR family transcriptional regulator
DSM104443_RS14730	ENOG4105E2D	ec 3.2.1.52
DSM104443_RS14735	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
DSM104443_RS14740	ENOG4105CI1	PTS System
DSM104443_RS14750	ENOG4105CHR	reductase
DSM104443_RS14760	ENOG4108TGY	Glutathione S-transferase
DSM104443_RS14765	ENOG4105KA0	thioesterase Superfamily protein
DSM104443_RS14790	ENOG4108RXX	maleylacetoacetate isomerase
DSM104443_RS14835	ENOG4105BZ1	(ABC) transporter
DSM104443_RS14850	ENOG4107R6D	beta-lactam binding protein AmpH
DSM104443_RS14865	ENOG4108YYC	ycei family
DSM104443_RS14880	ENOG4108R5S	membrane
DSM104443_RS14885	ENOG4105DKQ	ROK family
DSM104443_RS14895	ENOG4108IV0	ABC, transporter
DSM104443_RS14900	ENOG4105C32	Amino acid ABC transporter (Permease)
DSM104443_RS14905	ENOG41083Z3	extracellular ligand-binding receptor
DSM104443_RS14930	ENOG4105BZU	Histidine kinase
DSM104443_RS14945	ENOG4108ZJF	Glcg protein
DSM104443_RS14955	ENOG4108ZCF	integral membrane protein
DSM104443_RS14970	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
DSM104443_RS14975	ENOG4105DGI	Alkaline phosphatase
DSM104443_RS14990	ENOG410904N	short-chain dehydrogenase reductase
DSM104443_RS15005	ENOG4105KVH	Transcriptional regulator
DSM104443_RS15010	ENOG4108K3A	Glutathione S-transferase
DSM104443_RS15020	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DSM104443_RS15045	ENOG4105CI2	imidazolone-5-propionate hydrolase
DSM104443_RS15075	ENOG4108RAV	Conserved protein
DSM104443_RS15080	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
DSM104443_RS15085	ENOG4105HEI	LysR family (Transcriptional regulator
DSM104443_RS15115	ENOG4107QRI	Phosphoketolase
DSM104443_RS15120	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
DSM104443_RS15125	ENOG4105E3A	(ABC) transporter
DSM104443_RS15130	ENOG4105DA5	(ABC) transporter
DSM104443_RS15145	ENOG4105DWV	Homoserine O-trans-acetylase
DSM104443_RS15165	ENOG4108IUZ	ABC transporter
DSM104443_RS15170	ENOG4105C0Z	ABC transporter
DSM104443_RS15180	ENOG4105C32	Amino acid ABC transporter (Permease)
DSM104443_RS15200	ENOG4105R5N	Phosphoribosyl-dephospho-CoA transferase
DSM104443_RS15225	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
DSM104443_RS15235	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
DSM104443_RS15250	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
DSM104443_RS15265	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
DSM104443_RS15275	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
DSM104443_RS15285	ENOG4108YYQ	gCN5-related N-acetyltransferase
DSM104443_RS15290	ENOG4105DWV	Homoserine O-trans-acetylase
DSM104443_RS15305	ENOG4105E2V	Glycosyltransferase 36
DSM104443_RS15385	ENOG4105C0H	protease
DSM104443_RS15390	ENOG4105VEQ	Cold shock protein
DSM104443_RS15420	ENOG4105BZU	Histidine kinase
DSM104443_RS15445	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DSM104443_RS15455	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
DSM104443_RS15460	ENOG4108UJV	acyl-CoA thioesterase i
DSM104443_RS15470	ENOG4105WH1	Two component transcriptional regulator luxr family
DSM104443_RS15490	ENOG4108VWS	Yaeq family
DSM104443_RS15500	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
DSM104443_RS15505	ENOG4105DZ2	Transcriptional regulator
DSM104443_RS15510	ENOG4105CHP	RNA polymerase
DSM104443_RS15520	ENOG4105GRZ	Ycii-related protein
DSM104443_RS15530	ENOG4105GRZ	Ycii-related protein
DSM104443_RS15555	ENOG4105F2Z	3-oxoadipate enol-lactonase
DSM104443_RS15570	ENOG4108HRK	Histidine kinase
DSM104443_RS15575	ENOG4108VAC	response regulator
DSM104443_RS15590	ENOG4105DQE	DNA ligase
DSM104443_RS15595	ENOG4105FDF	Could be involved in DNA repair (By similarity)
DSM104443_RS15635	ENOG4108IND	Tetr family transcriptional regulator
DSM104443_RS15640	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
DSM104443_RS15655	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
DSM104443_RS15665	ENOG4105DUM	transcriptional regulator, lysR family
DSM104443_RS15670	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
DSM104443_RS15690	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
DSM104443_RS15710	ENOG4108UJU	UPF0301 protein
DSM104443_RS15725	ENOG4108YAB	Invasion protein
DSM104443_RS15740	ENOG4105CI0	Citrate lyase
DSM104443_RS15745	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DSM104443_RS15765	ENOG4108ZHJ	Organic hydroperoxide resistance protein
DSM104443_RS15785	ENOG4106PMH	Extracellular solute-binding protein family 3
DSM104443_RS15790	ENOG4105DRP	amino acid AbC transporter
DSM104443_RS15795	ENOG4105E5Q	amino acid AbC transporter
DSM104443_RS15810	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DSM104443_RS15835	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
DSM104443_RS15840	ENOG4105D05	Receptor
DSM104443_RS15850	ENOG4105C7W	Xanthine dehydrogenase
DSM104443_RS15855	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
DSM104443_RS15860	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
DSM104443_RS15870	ENOG4105E0Y	RtcB Protein
DSM104443_RS15880	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DSM104443_RS15885	ENOG4108YYH	Nadph-dependent fmn reductase
DSM104443_RS15895	ENOG4105C5R	Aminotransferase
DSM104443_RS15920	ENOG4106IQC	argininosuccinate lyase
DSM104443_RS15930	ENOG4106NZI	LysR family Transcriptional regulator
DSM104443_RS15945	ENOG4105KVH	Transcriptional regulator
DSM104443_RS15950	ENOG4105EUB	pirin domain protein
DSM104443_RS15960	ENOG4105E39	Enoyl-CoA hydratase
DSM104443_RS15980	ENOG4105CPC	Aldo Keto reductase
DSM104443_RS16005	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
DSM104443_RS16035	ENOG4105CEY	Amp-dependent synthetase and ligase
DSM104443_RS16055	ENOG4105C32	Amino acid ABC transporter (Permease)
DSM104443_RS16065	ENOG4105C0Z	ABC transporter
DSM104443_RS16070	ENOG4108IV0	ABC, transporter
DSM104443_RS16075	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
DSM104443_RS16080	ENOG4105C8Q	Methyl-accepting chemotaxis
DSM104443_RS16085	ENOG4105CHR	reductase
DSM104443_RS16100	ENOG4108ZX5	transcriptional regulator
DSM104443_RS16120	ENOG4105K63	Thioredoxin
DSM104443_RS16175	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DSM104443_RS16195	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DSM104443_RS16200	ENOG4105CXN	decarboxylase
DSM104443_RS16210	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
DSM104443_RS16225	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
DSM104443_RS16245	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DSM104443_RS16250	ENOG4107TUY	Histidine kinase
DSM104443_RS16260	ENOG4108TQ9	Histidine kinase
DSM104443_RS16265	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
DSM104443_RS16290	ENOG4105EAH	synthase
DSM104443_RS16295	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
DSM104443_RS16300	ENOG4105K46	50S ribosomal protein l27
DSM104443_RS16305	ENOG4108NIW	Leucine export protein LeuE
DSM104443_RS16310	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSM104443_RS16315	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
DSM104443_RS16340	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
DSM104443_RS16345	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DSM104443_RS16350	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DSM104443_RS16355	ENOG4105E4C	Lytic transglycosylase catalytic
DSM104443_RS16370	ENOG4107S2Z	UPF0761 membrane protein
DSM104443_RS16375	ENOG4105CS1	NAD(P)H quinone oxidoreductase
DSM104443_RS16390	ENOG4105DQR	SNARE associated Golgi
DSM104443_RS16395	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DSM104443_RS16400	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DSM104443_RS16405	ENOG4105VIE	preprotein translocase, subunit YajC
DSM104443_RS16410	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
DSM104443_RS16420	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DSM104443_RS16425	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
DSM104443_RS16430	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
DSM104443_RS16440	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
DSM104443_RS16445	ENOG4105W49	UPF0434 protein
DSM104443_RS16450	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
DSM104443_RS16455	ENOG4105M8F	Biopolymer transport protein exbD tolR
DSM104443_RS16465	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DSM104443_RS16470	ENOG41084UG	Pfam:DUF1458
DSM104443_RS16475	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
DSM104443_RS16480	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
DSM104443_RS16485	ENOG4105BZU	Histidine kinase
DSM104443_RS16490	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
DSM104443_RS16495	ENOG4105K8N	protein family UPF0079, ATPase
DSM104443_RS16500	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
DSM104443_RS16525	ENOG4105BZU	Histidine kinase
DSM104443_RS16530	ENOG4105BZU	Histidine kinase
DSM104443_RS16550	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
DSM104443_RS16555	ENOG4105E0C	molybdate abc transporter
DSM104443_RS16570	ENOG4105DKB	L-sorbosone dehydrogenase
DSM104443_RS16580	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
DSM104443_RS16590	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
DSM104443_RS16595	ENOG4105C8U	phosphate abc transporter
DSM104443_RS16600	ENOG4105E2Z	phosphate ABC transporter (Permease
DSM104443_RS16605	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DSM104443_RS16615	ENOG41080IJ	Diacylglycerol kinase
DSM104443_RS16620	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DSM104443_RS16635	ENOG4105BZU	Histidine kinase
DSM104443_RS16640	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DSM104443_RS16645	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
DSM104443_RS16655	ENOG4107S2Z	UPF0761 membrane protein
DSM104443_RS16680	ENOG4105D5T	phosphonate abc transporter
DSM104443_RS16690	ENOG4105S7S	phosphonate abc transporter
DSM104443_RS16695	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
DSM104443_RS16700	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
DSM104443_RS16705	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
DSM104443_RS16710	ENOG4105C08	Histidine kinase
DSM104443_RS16715	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
DSM104443_RS16735	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
DSM104443_RS16745	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DSM104443_RS16770	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
DSM104443_RS16775	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DSM104443_RS16805	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
DSM104443_RS16825	ENOG4105UGU	tonB-dependent Receptor
DSM104443_RS16900	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
DSM104443_RS16905	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
DSM104443_RS16910	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DSM104443_RS16925	ENOG4105DJ9	glucan biosynthesis protein
DSM104443_RS16935	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104443_RS16955	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
DSM104443_RS16960	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
DSM104443_RS16970	ENOG4105KHC	sulfurtransferase
DSM104443_RS17010	ENOG4105EXW	epimerase dehydratase
DSM104443_RS17040	ENOG4105M4H	endoribonuclease L-psp
DSM104443_RS17050	ENOG4105C7B	Threonine dehydratase
DSM104443_RS17070	ENOG4107QP8	phosphohexose isomerase
DSM104443_RS17075	ENOG4105BZU	Histidine kinase
DSM104443_RS17080	ENOG4105D7N	magnesium and cobalt transport protein CorA
DSM104443_RS17090	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
DSM104443_RS17100	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DSM104443_RS17105	ENOG4105C8S	subunit m
DSM104443_RS17115	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DSM104443_RS17120	ENOG4105DF2	NADH dehydrogenase subunit j
DSM104443_RS17125	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DSM104443_RS17130	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
DSM104443_RS17135	ENOG4108IEH	NADH dehydrogenase subunit g
DSM104443_RS17140	ENOG4107QIZ	NADH dehydrogenase
DSM104443_RS17155	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DSM104443_RS17160	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DSM104443_RS17165	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DSM104443_RS17170	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DSM104443_RS17180	ENOG4107EJC	Preprotein translocase subunit SecG
DSM104443_RS17185	ENOG4105CP7	Triose-phosphate isomerase
DSM104443_RS17205	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DSM104443_RS17210	ENOG4105EEI	dihydropteroate synthase
DSM104443_RS17215	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DSM104443_RS17220	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
DSM104443_RS17225	ENOG4105HBR	Rna-binding protein
DSM104443_RS17230	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
DSM104443_RS17235	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
DSM104443_RS17240	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
DSM104443_RS17245	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
DSM104443_RS17250	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
DSM104443_RS17255	ENOG41090R7	Ferric uptake
DSM104443_RS17260	ENOG4105KIP	Thioesterase
DSM104443_RS17275	ENOG4105C26	Dehydrogenase
DSM104443_RS17280	ENOG41080RH	Thioredoxin
DSM104443_RS17295	ENOG4105EUB	pirin domain protein
DSM104443_RS17300	ENOG4108SB3	DoxX Family
DSM104443_RS17310	ENOG4105EQ1	Transcriptional regulator
DSM104443_RS17315	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
DSM104443_RS17335	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
DSM104443_RS17360	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
DSM104443_RS17365	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DSM104443_RS17370	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
DSM104443_RS17375	ENOG4105CEY	Amp-dependent synthetase and ligase
DSM104443_RS17385	ENOG4105D9P	serine threonine protein kinase
DSM104443_RS17395	ENOG4105VEJ	Heat shock protein
DSM104443_RS17415	ENOG4108V1U	phospholipid-binding protein
DSM104443_RS17420	ENOG4108V1T	peptidylprolyl cis-trans isomerase
DSM104443_RS17425	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
DSM104443_RS17430	ENOG4105C26	Dehydrogenase
DSM104443_RS17435	ENOG4105DEF	Extracellular solute-binding protein, family 5
DSM104443_RS17440	ENOG4105BZU	Histidine kinase
DSM104443_RS17485	ENOG4105DEF	Extracellular solute-binding protein, family 5
DSM104443_RS17505	ENOG4105MIR	Phenylalanine 4-monooxygenase
DSM104443_RS17515	ENOG4105F1J	Homogentisate 1,2-dioxygenase
DSM104443_RS17520	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
DSM104443_RS17525	ENOG4105EW9	transcriptional regulator AsnC family
DSM104443_RS17540	ENOG4105DEF	Extracellular solute-binding protein, family 5
DSM104443_RS17545	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS17550	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS17570	ENOG4108JQ7	(ABC) transporter
DSM104443_RS17575	ENOG4105BZU	Histidine kinase
DSM104443_RS17610	ENOG4105CQ7	ATP-dependent helicase
DSM104443_RS17630	ENOG4108NIW	Leucine export protein LeuE
DSM104443_RS17650	ENOG4108K3A	Glutathione S-transferase
DSM104443_RS17655	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DSM104443_RS17660	ENOG4105C5I	Dehydrogenase
DSM104443_RS17680	ENOG4105CH5	extracellular solute-binding protein, family 7
DSM104443_RS17690	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
DSM104443_RS17695	ENOG4107QR9	Iron-sulfur cluster binding protein
DSM104443_RS17700	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
DSM104443_RS17705	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
DSM104443_RS17715	ENOG41061WM	D-Alanyl-D-Alanine
DSM104443_RS17735	ENOG4108JJ7	ABC transporter
DSM104443_RS17750	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
DSM104443_RS17755	ENOG4105C0H	protease
DSM104443_RS17810	ENOG4108IEG	Formate dehydrogenase Alpha subunit
DSM104443_RS17830	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
DSM104443_RS17835	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
DSM104443_RS17880	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
DSM104443_RS17885	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
DSM104443_RS17900	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
DSM104443_RS17905	ENOG4105CFN	oxalyl-CoA decarboxylase
DSM104443_RS17935	ENOG4108ZCF	integral membrane protein
DSM104443_RS17940	ENOG4107SC1	transglycosylase
DSM104443_RS17950	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DSM104443_RS17960	ENOG4105H1G	trap transporter solute receptor taxi family
DSM104443_RS17965	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
DSM104443_RS17970	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
DSM104443_RS17985	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
DSM104443_RS17990	ENOG4105C5R	Aminotransferase
DSM104443_RS18000	ENOG4105ERG	peptidase m48, ste24p
DSM104443_RS18015	ENOG4105SYT	Methylenetetrahydrofolate reductase
DSM104443_RS18030	ENOG4108N27	Glutathione S-transferase
DSM104443_RS18035	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
DSM104443_RS18045	ENOG4105D1S	lipid A biosynthesis
DSM104443_RS18050	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
DSM104443_RS18060	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DSM104443_RS18065	ENOG4105CKI	cobalamin synthesis protein
DSM104443_RS18070	ENOG4105CKI	cobalamin synthesis protein
DSM104443_RS18075	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DSM104443_RS18095	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
DSM104443_RS18100	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
DSM104443_RS18120	ENOG4105E18	UPF0276 protein
DSM104443_RS18145	ENOG4107Y70	Heat shock protein
DSM104443_RS18150	ENOG4105CAS	nag kinase
DSM104443_RS18155	ENOG4105X23	Endonuclease Exonuclease phosphatase
DSM104443_RS18160	ENOG41062IR	nudix hydrolase
DSM104443_RS18165	ENOG4105D44	asparaginase
DSM104443_RS18170	ENOG4105C9M	aspartyl-trna synthetase
DSM104443_RS18190	ENOG4105D0M	Protease HtpX homolog
DSM104443_RS18215	ENOG4108UUM	single-stranded DNA-binding protein
DSM104443_RS18220	ENOG4107RDB	Major Facilitator
DSM104443_RS18225	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DSM104443_RS18245	ENOG4108ZT0	50S ribosomal protein l17
DSM104443_RS18250	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DSM104443_RS18255	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DSM104443_RS18265	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DSM104443_RS18270	ENOG41067V7	50S ribosomal protein L36
DSM104443_RS18275	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
DSM104443_RS18280	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
DSM104443_RS18285	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
DSM104443_RS18290	ENOG4105VPB	50S ribosomal protein L30
DSM104443_RS18295	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
DSM104443_RS18300	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
DSM104443_RS18305	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
DSM104443_RS18310	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
DSM104443_RS18320	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DSM104443_RS18325	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
DSM104443_RS18330	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
DSM104443_RS18335	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
DSM104443_RS18340	ENOG41084PQ	50s ribosomal protein l29
DSM104443_RS18345	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
DSM104443_RS18355	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DSM104443_RS18360	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
DSM104443_RS18365	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DSM104443_RS18370	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
DSM104443_RS18375	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DSM104443_RS18385	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
DSM104443_RS18395	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DSM104443_RS18400	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
DSM104443_RS18405	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
DSM104443_RS18410	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DSM104443_RS18415	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DSM104443_RS18420	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
DSM104443_RS18425	ENOG4108VZM	50s ribosomal protein L10
DSM104443_RS18430	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
DSM104443_RS18435	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
DSM104443_RS18440	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
DSM104443_RS18445	ENOG4105PM1	preprotein translocase subunit SecE
DSM104443_RS18480	ENOG4105KB2	stringent starvation protein b
DSM104443_RS18485	ENOG4107MKT	Stringent starvation protein a
DSM104443_RS18490	ENOG4105EIX	cytochrome c1
DSM104443_RS18495	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DSM104443_RS18500	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DSM104443_RS18505	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
DSM104443_RS18510	ENOG4105C0H	protease
DSM104443_RS18515	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
DSM104443_RS18520	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
DSM104443_RS18525	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
DSM104443_RS18530	ENOG4105K59	histidine triad (HIT) protein
DSM104443_RS18535	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
DSM104443_RS18540	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
DSM104443_RS18550	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
DSM104443_RS18555	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
DSM104443_RS18560	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
DSM104443_RS18565	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DSM104443_RS18570	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
DSM104443_RS18580	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
DSM104443_RS18590	ENOG4105E3A	(ABC) transporter
DSM104443_RS18595	ENOG4105DA5	(ABC) transporter
DSM104443_RS18605	ENOG4105E3I	toluene tolerance
DSM104443_RS18610	ENOG4107PE3	Mammalian cell entry related domain protein
DSM104443_RS18615	ENOG4105CY3	ABC transporter, permease
DSM104443_RS18620	ENOG4105DHJ	ABC, transporter
DSM104443_RS18635	ENOG4105GVR	general secretion pathway protein D
DSM104443_RS18645	ENOG4107QHF	type ii secretion system protein e
DSM104443_RS18680	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
DSM104443_RS18695	ENOG4105UYK	outer membrane protein a
DSM104443_RS18700	ENOG4108VPT	UPF0234 protein
DSM104443_RS18715	ENOG4105DBV	ornithine carbamoyltransferase
DSM104443_RS18720	ENOG4105C8Y	Acetylornithine aminotransferase
DSM104443_RS18725	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
DSM104443_RS18730	ENOG4105CJR	Integral membrane protein (MviN
DSM104443_RS18735	ENOG4105DTN	riboflavin biosynthesis protein ribF
DSM104443_RS18740	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DSM104443_RS18745	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
DSM104443_RS18750	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
DSM104443_RS18805	ENOG4106H29	UPF0391 membrane protein
DSM104443_RS18815	ENOG4105RQ9	TPR repeat-containing protein
DSM104443_RS18820	ENOG4105C7B	Threonine dehydratase
DSM104443_RS18825	ENOG4105E66	phosphoriboisomerase A
DSM104443_RS18830	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
DSM104443_RS18835	ENOG4108EKC	n-acetylglutamate synthase
DSM104443_RS18840	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
DSM104443_RS18850	ENOG4106032	Glutathionylspermidine synthase
DSM104443_RS18860	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
DSM104443_RS18865	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
DSM104443_RS18870	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DSM104443_RS18880	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DSM104443_RS18895	ENOG4105BZA	Phosphoglycerate kinase
DSM104443_RS18900	ENOG4105CA9	Pyruvate kinase
DSM104443_RS18915	ENOG4108YAB	Invasion protein
DSM104443_RS18925	ENOG4105C8V	SAICAR synthetase
DSM104443_RS18960	ENOG4105EE5	Membrane protein terC
DSM104443_RS18965	ENOG4107PP3	Acetylornithine deacetylase
DSM104443_RS18970	ENOG4105HF0	Membrane
DSM104443_RS18980	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
DSM104443_RS18990	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
DSM104443_RS19015	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
DSM104443_RS19020	ENOG4105FAW	cDP-glucose 4,6-dehydratase
DSM104443_RS19025	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
DSM104443_RS19040	ENOG4105DKP	glycosyl transferase, family 9
DSM104443_RS19045	ENOG4107T8Q	Glycosyl transferase (Group 1
DSM104443_RS19050	ENOG4105BZ1	(ABC) transporter
DSM104443_RS19055	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DSM104443_RS19100	ENOG4105EY8	ABC transporter
DSM104443_RS19110	ENOG4105MFV	ABC-2 type transporter
DSM104443_RS19140	ENOG4105GVR	general secretion pathway protein D
DSM104443_RS19160	ENOG4105UV2	general secretion pathway protein K
DSM104443_RS19175	ENOG4105VWV	general secretion pathway protein h
DSM104443_RS19180	ENOG4108VAU	general secretion pathway protein G
DSM104443_RS19185	ENOG4105D7Q	type ii secretion system
DSM104443_RS19190	ENOG4107QHF	type ii secretion system protein e
DSM104443_RS19195	ENOG4105BZU	Histidine kinase
DSM104443_RS19210	ENOG4105W0Z	cytoplasmic protein
DSM104443_RS19215	ENOG4105C0P	Mg chelatase subunit ChlI
DSM104443_RS19220	ENOG4105C2C	drug resistance transporter, Bcr CflA
DSM104443_RS19260	ENOG4108T2C	cysteine dioxygenase type I
DSM104443_RS19345	ENOG4105C3R	Methionine synthase
DSM104443_RS19370	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DSM104443_RS19375	ENOG4105CYM	Glutathione S-transferase
DSM104443_RS19380	ENOG4108JUA	Transcriptional regulator
DSM104443_RS19385	ENOG4106BE1	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers (By similarity)
DSM104443_RS19395	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DSM104443_RS19405	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DSM104443_RS19410	ENOG4105CTB	Polyprenyl synthetase
DSM104443_RS19415	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DSM104443_RS19440	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DSM104443_RS19475	ENOG4108JJA	ABC, transporter
DSM104443_RS19490	ENOG4105KHC	sulfurtransferase
DSM104443_RS19515	ENOG4108PYU	two-component system response regulator
DSM104443_RS19520	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
DSM104443_RS19525	ENOG4105KRF	dihydroneopterin aldolase
DSM104443_RS19540	ENOG4108Z66	YbaK ebsC protein
DSM104443_RS19550	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DSM104443_RS19555	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DSM104443_RS19560	ENOG4105DG4	malate L-lactate dehydrogenase
DSM104443_RS19605	ENOG4106DSS	Tartrate dehydratase subunit alpha
DSM104443_RS19630	ENOG4105HMI	Membrane
DSM104443_RS19635	ENOG4105CTX	dehydratase
DSM104443_RS19640	ENOG4105VP7	SAF domain protein
DSM104443_RS19655	ENOG4105CGZ	zinc metallopeptidase
DSM104443_RS19665	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
DSM104443_RS19670	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
DSM104443_RS19675	ENOG4105K5M	30s ribosomal protein S16
DSM104443_RS19685	ENOG4105CWC	Acetylornithine deacetylase
DSM104443_RS19695	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
DSM104443_RS19705	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DSM104443_RS19710	ENOG4105CRE	cytochrome C
DSM104443_RS19715	ENOG4108JU6	CBS domain protein
DSM104443_RS19770	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
DSM104443_RS19780	ENOG4105CSR	polyphosphate kinase 2
DSM104443_RS19795	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
DSM104443_RS19805	ENOG41083UI	stage II sporulation protein
DSM104443_RS19815	ENOG4108KK1	membrane protein AbrB duplication
DSM104443_RS19820	ENOG4105K2J	Transcriptional regulator
DSM104443_RS19850	ENOG4105CNV	Aldolase
DSM104443_RS19880	ENOG4105DHQ	Histidine kinase
DSM104443_RS19920	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
DSM104443_RS19970	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DSM104443_RS19985	ENOG4105HEI	LysR family (Transcriptional regulator
DSM104443_RS20020	ENOG4105CHR	reductase
DSM104443_RS20035	ENOG4108PGP	mmge prpd family protein
DSM104443_RS20065	ENOG4105DDW	LysR family Transcriptional regulator
DSM104443_RS20100	ENOG4105CBN	LysR family transcriptional regulator
DSM104443_RS20110	ENOG4108Z9K	Osmotically inducible protein
DSM104443_RS20135	ENOG4105WH1	Two component transcriptional regulator luxr family
DSM104443_RS20165	ENOG4105NE1	Conserved Protein
DSM104443_RS20180	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
DSM104443_RS20220	ENOG4105M0T	TPR Repeat-Containing Protein
DSM104443_RS20225	ENOG4107SVH	Potassium channel protein
DSM104443_RS20235	ENOG4105EUB	pirin domain protein
DSM104443_RS20240	ENOG41080Z8	PHOSPHOCARRIER protein
DSM104443_RS20250	ENOG4105BZU	Histidine kinase
DSM104443_RS20270	ENOG4105CVE	Lytic murein transglycosylase
DSM104443_RS20280	ENOG4105CBX	hi0933 family
DSM104443_RS20290	ENOG4105CPC	Aldo Keto reductase
DSM104443_RS20300	ENOG4105DWV	Homoserine O-trans-acetylase
DSM104443_RS20320	ENOG4105E6M	Sulphatase-modifying factor protein
DSM104443_RS20330	ENOG4105CSW	GntR family transcriptional regulator
DSM104443_RS20335	ENOG4105CJ1	ABC, transporter
DSM104443_RS20365	ENOG4105CN1	protease
DSM104443_RS20385	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DSM104443_RS20400	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DSM104443_RS20405	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
DSM104443_RS20415	ENOG4105BZU	Histidine kinase
DSM104443_RS20420	ENOG4105BZU	Histidine kinase
DSM104443_RS20435	ENOG4105FUA	antagonist
DSM104443_RS20440	ENOG4107MMM	Anti-sigma-factor antagonist
DSM104443_RS20445	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
DSM104443_RS20465	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
DSM104443_RS20480	ENOG4105CSU	acyl-Coa dehydrogenase
DSM104443_RS20485	ENOG4105KAV	tspo and mbr like protein
DSM104443_RS20500	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
DSM104443_RS20505	ENOG4108YXA	Membrane
DSM104443_RS20510	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
DSM104443_RS20550	ENOG4105DHZ	alpha beta
DSM104443_RS20555	ENOG4105NZG	Ferredoxin
DSM104443_RS20565	ENOG4108Z0R	Transferase
DSM104443_RS20580	ENOG4108VAC	response regulator
DSM104443_RS20585	ENOG4105C2F	Histidine kinase
DSM104443_RS20590	ENOG4108VAC	response regulator
DSM104443_RS20595	ENOG4108HRK	Histidine kinase
DSM104443_RS20600	ENOG4108VAC	response regulator
DSM104443_RS20605	ENOG4108HRK	Histidine kinase
DSM104443_RS20630	ENOG4108IJ9	(ABC) transporter
DSM104443_RS20640	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
DSM104443_RS20650	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS20670	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
DSM104443_RS20680	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
DSM104443_RS20685	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
DSM104443_RS20730	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DSM104443_RS20760	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
DSM104443_RS20765	ENOG4105EB3	Histidine kinase
DSM104443_RS20775	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DSM104443_RS20790	ENOG41080Z8	PHOSPHOCARRIER protein
DSM104443_RS20795	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
DSM104443_RS20800	ENOG4105BZU	Histidine kinase
DSM104443_RS20830	ENOG4105DWV	Homoserine O-trans-acetylase
DSM104443_RS20835	ENOG4105DWV	Homoserine O-trans-acetylase
DSM104443_RS20840	ENOG4105EYM	Major Facilitator superfamily
DSM104443_RS20845	ENOG4105E0X	reductase
DSM104443_RS20855	ENOG4105C5H	ABC transporter
DSM104443_RS20860	ENOG4105CGK	Exodeoxyribonuclease III
DSM104443_RS20865	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
DSM104443_RS20875	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DSM104443_RS20880	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DSM104443_RS20885	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DSM104443_RS20895	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
DSM104443_RS20900	ENOG4105VQ7	Rod shape-determining protein MreD
DSM104443_RS20905	ENOG4105CJN	penicillin-binding protein
DSM104443_RS20910	ENOG4105CNI	cell division protein FtsW
DSM104443_RS20915	ENOG4105K6T	rare lipoprotein A
DSM104443_RS20920	ENOG4105DZ1	carboxypeptidase
DSM104443_RS20925	ENOG4105F0I	Aminotransferase
DSM104443_RS20930	ENOG4108Z43	UPF0250 protein
DSM104443_RS20935	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
DSM104443_RS20960	ENOG4107QP3	malate synthase g
DSM104443_RS20975	ENOG4108NEV	two component transcriptional regulator, LytTR family
DSM104443_RS20980	ENOG4108HRK	Histidine kinase
DSM104443_RS20985	ENOG4105CH7	arginosuccinase
DSM104443_RS20995	ENOG4105XQ6	frataxin-like protein
DSM104443_RS21000	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DSM104443_RS21015	ENOG4105CJW	magnesium transporter
DSM104443_RS21020	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
DSM104443_RS21025	ENOG4105E2X	shikimate dehydrogenase
DSM104443_RS21040	ENOG4105CUX	Signal transduction histidine kinase
DSM104443_RS21045	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DSM104443_RS21050	ENOG4105BZU	Histidine kinase
DSM104443_RS21065	ENOG4105DGW	oligopeptidase A
DSM104443_RS21070	ENOG4105CD3	dihydroorotase
DSM104443_RS21075	ENOG4105CXT	aspartate transcarbamylase
DSM104443_RS21080	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
DSM104443_RS21085	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
DSM104443_RS21090	ENOG4108UJU	UPF0301 protein
DSM104443_RS21095	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
DSM104443_RS21135	ENOG4105IPS	esterase
DSM104443_RS21140	ENOG4105JAB	phenazine biosynthesis protein, phzf family
DSM104443_RS21145	ENOG4105DFU	Cell wall formation (By similarity)
DSM104443_RS21160	ENOG4105D7Z	glutathione synthase
DSM104443_RS21185	ENOG4105W39	Membrane
DSM104443_RS21190	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
DSM104443_RS21200	ENOG4105ECF	c-methyltransferase
DSM104443_RS21215	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DSM104443_RS21230	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104443_RS21235	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
DSM104443_RS21240	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
DSM104443_RS21245	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
DSM104443_RS21250	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DSM104443_RS21265	ENOG4107T4Z	adenosine kinase
DSM104443_RS21275	ENOG4108Z20	Acyl-transferase
DSM104443_RS21280	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
DSM104443_RS21285	ENOG4105MPD	Cytochrome
DSM104443_RS21310	ENOG4105ESV	Glycosyl transferase, family 4
DSM104443_RS21345	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
DSM104443_RS21350	ENOG4105C25	Primosomal protein n'
DSM104443_RS21355	ENOG4105C75	arginyL-tRNA synthetase
DSM104443_RS21365	ENOG4108Z33	Thiol disulfide Interchange Protein
DSM104443_RS21370	ENOG4107FW0	short-chain dehydrogenase reductase
DSM104443_RS21375	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
DSM104443_RS21385	ENOG4105D2X	ABC transporter substrate-binding protein
DSM104443_RS21390	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
DSM104443_RS21395	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
DSM104443_RS21405	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
DSM104443_RS21420	ENOG4105C5H	ABC transporter
DSM104443_RS21430	ENOG4105C9K	Endothelin-converting enzyme 1
DSM104443_RS21440	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DSM104443_RS21450	ENOG4105DCM	major facilitator superfamily
DSM104443_RS21455	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
DSM104443_RS21490	ENOG4107QXX	ABC transporter
DSM104443_RS21495	ENOG4105EZ7	amino acid ABC transporter
DSM104443_RS21500	ENOG4105DRP	amino acid AbC transporter
DSM104443_RS21505	ENOG4105CDA	abc transporter atp-binding protein
DSM104443_RS21515	ENOG4105E8R	UPF0173 metal-dependent hydrolase
DSM104443_RS21540	ENOG4105EGI	Transcriptional regulator
DSM104443_RS21550	ENOG4105CBP	Major Facilitator
DSM104443_RS21565	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DSM104443_RS21585	ENOG4105F8J	Adenylate Guanylate cyclase
DSM104443_RS21600	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DSM104443_RS21605	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
DSM104443_RS21610	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
DSM104443_RS21615	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
DSM104443_RS21620	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
DSM104443_RS21625	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DSM104443_RS21630	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DSM104443_RS21635	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DSM104443_RS21640	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
DSM104443_RS21650	ENOG4105FA0	parb-like partition protein
DSM104443_RS21655	ENOG4107QJE	Chromosome Partitioning Protein
DSM104443_RS21660	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
DSM104443_RS21665	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
DSM104443_RS21680	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
DSM104443_RS21685	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DSM104443_RS21690	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
DSM104443_RS21695	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
DSM104443_RS21700	ENOG4105VG0	50S ribosomal protein l34