locus-tag	class	description
H0S67_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
H0S67_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
H0S67_RS00015	ENOG4108J5G	6-phosphogluconate dehydrogenase
H0S67_RS00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
H0S67_RS00025	ENOG4105K7N	UPF0232 protein
H0S67_RS00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H0S67_RS00110	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
H0S67_RS00115	ENOG4107ZXI	Rhomboid family
H0S67_RS00155	ENOG4105HZM	Fha domain containing protein
H0S67_RS00160	ENOG4105TV9	FHA Domain-Containing protein
H0S67_RS00185	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
H0S67_RS00205	ENOG4105ETX	regulatoR
H0S67_RS00220	ENOG4108V06	Glutathione peroxidase
H0S67_RS00250	ENOG4105EEF	Alkane 1-monooxygenase
H0S67_RS00295	ENOG4107VP5	methyltetrahydrofolate corrinoid iron-sulfur protein methyltransferase
H0S67_RS00300	ENOG4108Q52	Methyltransferase cognate corrinoid protein
H0S67_RS00310	ENOG4105F5V	trimethylamine methyltransferase
H0S67_RS00320	ENOG4107HP6	Transcriptional regulator
H0S67_RS00335	ENOG4108IJ7	Glycine betaine
H0S67_RS00340	ENOG4108HQS	Glycine betaine
H0S67_RS00355	ENOG4105BZJ	Electron transfer flavoprotein
H0S67_RS00360	ENOG4105C10	Electron transfer flavoprotein
H0S67_RS00385	ENOG4105C9K	Endothelin-converting enzyme 1
H0S67_RS00395	ENOG4105GR3	Histidine kinase
H0S67_RS00405	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H0S67_RS00410	ENOG4105EXC	Acyl-transferase
H0S67_RS00415	ENOG4107QZ7	Cellulose synthase catalytic subunit
H0S67_RS00420	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H0S67_RS00430	ENOG4105C0D	helicase
H0S67_RS00445	ENOG4105VPX	protein, conserved in bacteria
H0S67_RS00455	ENOG41080RH	Thioredoxin
H0S67_RS00465	ENOG4107TPS	domain protein
H0S67_RS00470	ENOG4108VCT	Sulfite exporter TauE/SafE
H0S67_RS00480	ENOG4107QX3	carboxylase
H0S67_RS00555	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
H0S67_RS00565	ENOG4108QER	Adenylate cyclase
H0S67_RS00575	ENOG4105CEU	Arginine dihydrolase
H0S67_RS00585	ENOG4105C8M	UPF0272 protein
H0S67_RS00620	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
H0S67_RS00650	ENOG4108KP7	hydrolase
H0S67_RS00670	ENOG4108VC7	Protein of unknown function (DUF2587)
H0S67_RS00685	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
H0S67_RS00735	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
H0S67_RS00760	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
H0S67_RS00765	ENOG4106NZI	LysR family Transcriptional regulator
H0S67_RS00770	ENOG4105D94	Major Facilitator Superfamily
H0S67_RS00780	ENOG4108VVK	transcriptional Regulator, AsnC
H0S67_RS00790	ENOG4105CPP	Dehydrogenase, E1 component
H0S67_RS00795	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
H0S67_RS00805	ENOG4105DXM	phenylacetic acid degradation protein
H0S67_RS00810	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
H0S67_RS00815	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
H0S67_RS00830	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
H0S67_RS00835	ENOG4105E39	Enoyl-CoA hydratase
H0S67_RS00845	ENOG4108ZJI	phenylacetic acid degradation protein
H0S67_RS00860	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
H0S67_RS00895	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
H0S67_RS00900	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
H0S67_RS00910	ENOG4108UYE	Lactoylglutathione lyase
H0S67_RS00925	ENOG4105CHU	acetyl-coa acetyltransferase
H0S67_RS00965	ENOG4108V5V	Serine Threonine protein kinase
H0S67_RS01080	ENOG4107RQ0	Maleylacetate reductase
H0S67_RS01085	ENOG4107SM8	Adenylate Guanylate cyclase
H0S67_RS01095	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H0S67_RS01105	ENOG4105DSY	exodeoxyribonuclease V, gamma
H0S67_RS01150	ENOG4105DXX	methyltransferase
H0S67_RS01165	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H0S67_RS01210	ENOG4108YXG	UPF0502 protein
H0S67_RS01250	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
H0S67_RS01260	ENOG4108YZT	Adenosylcobinamide kinase
H0S67_RS01270	ENOG4105EHG	Permease protein
H0S67_RS01275	ENOG4105E0A	ABC, transporter
H0S67_RS01290	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
H0S67_RS01335	ENOG4105VEQ	Cold shock protein
H0S67_RS01345	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
H0S67_RS01385	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
H0S67_RS01425	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H0S67_RS01430	ENOG4105C1G	acyl-Coa dehydrogenase
H0S67_RS01440	ENOG4105ETE	Transcriptional regulator (LacI family
H0S67_RS01455	ENOG4105EG2	ABC transporter, permease
H0S67_RS01470	ENOG4105W8H	transhydrogenase (subunit alpha
H0S67_RS01475	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H0S67_RS01485	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
H0S67_RS01495	ENOG4108Z6B	deaminase
H0S67_RS01510	ENOG4108X07	Tetr family transcriptional regulator
H0S67_RS01530	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
H0S67_RS01540	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
H0S67_RS01545	ENOG4105C2C	drug resistance transporter, Bcr CflA
H0S67_RS01595	ENOG4105CSV	Glutaminase
H0S67_RS01615	ENOG4105C2J	ABC transporter
H0S67_RS01620	ENOG4105CNN	ABC, transporter
H0S67_RS01630	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
H0S67_RS01650	ENOG4108UYE	Lactoylglutathione lyase
H0S67_RS01655	ENOG4105CHR	reductase
H0S67_RS01670	ENOG4105ERH	Fumarylacetoacetate hydrolase
H0S67_RS01725	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS01790	ENOG4105NTD	Inherit from COG: Hydrolase
H0S67_RS01795	ENOG4105CHR	reductase
H0S67_RS01805	ENOG4105ETE	Transcriptional regulator (LacI family
H0S67_RS01810	ENOG4105C2J	ABC transporter
H0S67_RS01830	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
H0S67_RS01845	ENOG4105DET	Rhamnulokinase
H0S67_RS01850	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
H0S67_RS01855	ENOG4107QR9	Iron-sulfur cluster binding protein
H0S67_RS01860	ENOG41080R8	Conserved Protein
H0S67_RS01910	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
H0S67_RS01925	ENOG4105CIG	ABC transporter
H0S67_RS01930	ENOG4105E39	Enoyl-CoA hydratase
H0S67_RS01985	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
H0S67_RS02030	ENOG4107RB3	L-asparaginase
H0S67_RS02055	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
H0S67_RS02065	ENOG4105CFH	Aspartokinase
H0S67_RS02070	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
H0S67_RS02095	ENOG4105BZ4	penicillin-binding protein
H0S67_RS02185	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H0S67_RS02190	ENOG4105P8F	nudix hydrolase
H0S67_RS02205	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
H0S67_RS02210	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
H0S67_RS02235	ENOG4105C26	Dehydrogenase
H0S67_RS02240	ENOG4105CUB	amino acid
H0S67_RS02245	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
H0S67_RS02250	ENOG4105DCF	alanine dehydrogenase
H0S67_RS02255	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
H0S67_RS02270	ENOG4105CPF	Cell wall formation (By similarity)
H0S67_RS02280	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H0S67_RS02285	ENOG4105C1G	acyl-Coa dehydrogenase
H0S67_RS02390	ENOG4108I5C	dEAD DEAH box helicase
H0S67_RS02395	ENOG4105WN5	stage II sporulation protein
H0S67_RS02400	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H0S67_RS02410	ENOG4105RHY	Pfam:UPF0157
H0S67_RS02420	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
H0S67_RS02425	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
H0S67_RS02430	ENOG4107QRG	dna polymerase iii
H0S67_RS02485	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
H0S67_RS02490	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
H0S67_RS02500	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
H0S67_RS02530	ENOG4105BZU	Histidine kinase
H0S67_RS02570	ENOG4107SVH	Potassium channel protein
H0S67_RS02575	ENOG4105BZP	glycoside hydrolase 15-related
H0S67_RS02600	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
H0S67_RS02605	ENOG4108KPJ	rna polymerase sigma factor
H0S67_RS02620	ENOG4108UCS	ABC, transporter
H0S67_RS02640	ENOG4105F0N	pyrophosphate phospho-hydrolase
H0S67_RS02650	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
H0S67_RS02655	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
H0S67_RS02685	ENOG4105EUJ	GTP cyclohydrolase i
H0S67_RS02720	ENOG4108IJ8	ABC transporter
H0S67_RS02725	ENOG4105E90	ABC transporter
H0S67_RS02730	ENOG4107U14	binding-protein-dependent transport systems inner membrane Component
H0S67_RS02735	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
H0S67_RS02740	ENOG4105K64	Glycosyl transferase, family 2
H0S67_RS02770	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
H0S67_RS02775	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
H0S67_RS02780	ENOG4108IYU	L-aspartate oxidase
H0S67_RS02790	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
H0S67_RS02815	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
H0S67_RS02820	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
H0S67_RS02825	ENOG4105ETE	Transcriptional regulator (LacI family
H0S67_RS02840	ENOG4108JWX	
H0S67_RS02845	ENOG4107R33	ppx gppa phosphatase
H0S67_RS02850	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
H0S67_RS02860	ENOG4105CJ1	ABC, transporter
H0S67_RS02870	ENOG41062BK	proline dehydrogenase
H0S67_RS02875	ENOG4105II7	pyrroline-5-carboxylate reductase
H0S67_RS02880	ENOG4108J2P	Alpha beta hydrolase fold
H0S67_RS02885	ENOG4105DWV	Homoserine O-trans-acetylase
H0S67_RS02890	ENOG4105C31	Tryptophanyl-tRNA synthetase
H0S67_RS02895	ENOG4105DGU	Histone deacetylase
H0S67_RS02950	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
H0S67_RS02955	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
H0S67_RS02960	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
H0S67_RS02965	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
H0S67_RS02970	ENOG4105D52	delta-aminolevulinic acid dehydratase
H0S67_RS02985	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
H0S67_RS02990	ENOG4108RH7	phosphoglycerate mutase
H0S67_RS02995	ENOG4107QX9	Thiol disulfide interChange protein
H0S67_RS03000	ENOG4107QIV	Cytochrome c biogenesis protein
H0S67_RS03010	ENOG4105CRE	cytochrome C
H0S67_RS03075	ENOG4105E8R	UPF0173 metal-dependent hydrolase
H0S67_RS03095	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H0S67_RS03105	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H0S67_RS03110	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H0S67_RS03115	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H0S67_RS03125	ENOG4107QIZ	NADH dehydrogenase
H0S67_RS03140	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H0S67_RS03145	ENOG41087XN	oxidoreductase
H0S67_RS03150	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H0S67_RS03170	ENOG4105EAH	synthase
H0S67_RS03190	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
H0S67_RS03195	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
H0S67_RS03200	ENOG4108I5D	sulfate abc transporter
H0S67_RS03210	ENOG4108IJ6	ABC transporter
H0S67_RS03215	ENOG4108VPT	UPF0234 protein
H0S67_RS03235	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
H0S67_RS03255	ENOG4105CEY	Amp-dependent synthetase and ligase
H0S67_RS03265	ENOG4105C1G	acyl-Coa dehydrogenase
H0S67_RS03280	ENOG4105CQB	FAD linked oxidase domain protein
H0S67_RS03285	ENOG4105CQB	FAD linked oxidase domain protein
H0S67_RS03290	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
H0S67_RS03295	ENOG4105DAA	L-lactate
H0S67_RS03315	ENOG4105C1G	acyl-Coa dehydrogenase
H0S67_RS03320	ENOG41080HI	glycine oxidase
H0S67_RS03345	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H0S67_RS03350	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
H0S67_RS03395	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H0S67_RS03405	ENOG4108UHU	Aldolase
H0S67_RS03410	ENOG4105C01	Dihydroxy-acid dehydratase
H0S67_RS03420	ENOG4105DKQ	ROK family
H0S67_RS03445	ENOG4105WDJ	50S ribosomal protein L33
H0S67_RS03450	ENOG410900P	UPF0336 protein
H0S67_RS03460	ENOG4107R4N	Cell wall formation (By similarity)
H0S67_RS03485	ENOG410683Z	Preprotein translocase SecE subunit
H0S67_RS03490	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
H0S67_RS03495	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
H0S67_RS03505	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
H0S67_RS03510	ENOG4108VZM	50s ribosomal protein L10
H0S67_RS03515	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
H0S67_RS03575	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H0S67_RS03580	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H0S67_RS03600	ENOG4105CQB	FAD linked oxidase domain protein
H0S67_RS03625	ENOG4108UVJ	appr-1-p processing domain protein
H0S67_RS03630	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
H0S67_RS03645	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H0S67_RS03685	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
H0S67_RS03705	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H0S67_RS03715	ENOG4105CG3	alpha amylase, catalytic region
H0S67_RS03745	ENOG4105EG6	Saccharopine dehydrogenase
H0S67_RS03770	ENOG4105C75	arginyL-tRNA synthetase
H0S67_RS03775	ENOG4108KGH	TRANSCRIPTIONal
H0S67_RS03900	ENOG4106839	domain protein
H0S67_RS03905	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
H0S67_RS03910	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
H0S67_RS03915	ENOG4105C5H	ABC transporter
H0S67_RS03925	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
H0S67_RS03940	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
H0S67_RS03990	ENOG4108ZJ4	polysaccharide deacetylase
H0S67_RS04000	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
H0S67_RS04040	ENOG4105CPC	Aldo Keto reductase
H0S67_RS04055	ENOG4105BZU	Histidine kinase
H0S67_RS04060	ENOG4107TPY	serine threonine protein kinase
H0S67_RS04065	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
H0S67_RS04115	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
H0S67_RS04120	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
H0S67_RS04190	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
H0S67_RS04195	ENOG4105NAE	bifunctional deaminase-reductase domain protein
H0S67_RS04210	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
H0S67_RS04230	ENOG4105CS9	pantothenic acid kinase
H0S67_RS04240	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H0S67_RS04275	ENOG4108FKE	two-component system sensor kinase
H0S67_RS04280	ENOG4108KXV	response regulator
H0S67_RS04310	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
H0S67_RS04320	ENOG4106517	Short-chain dehydrogenase reductase Sdr
H0S67_RS04345	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
H0S67_RS04350	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H0S67_RS04445	ENOG4108ESY	Metal dependent phosphohydrolase
H0S67_RS04500	ENOG4105H3G	oxidoreductase
H0S67_RS04510	ENOG410681U	heavy metal transport detoxification protein
H0S67_RS04520	ENOG4105CBG	Sulfatase
H0S67_RS04620	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H0S67_RS04635	ENOG4105C6Z	Gluconate
H0S67_RS04650	ENOG4107QPH	glycogen) synthase
H0S67_RS04655	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
H0S67_RS04660	ENOG4108VCA	G U mismatch-specific DNA glycosylase
H0S67_RS04710	ENOG4107QMH	DNA methylase
H0S67_RS04745	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
H0S67_RS04765	ENOG4105F95	Monooxygenase
H0S67_RS04780	ENOG4105EDW	glycosyl transferase, family 39
H0S67_RS04790	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0S67_RS04800	ENOG4105CQ7	ATP-dependent helicase
H0S67_RS04865	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
H0S67_RS04900	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS04915	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
H0S67_RS04920	ENOG4105E0X	reductase
H0S67_RS04940	ENOG4105KAF	membrAne
H0S67_RS04985	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
H0S67_RS04990	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
H0S67_RS05000	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
H0S67_RS05005	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
H0S67_RS05010	ENOG4108RM3	Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I- 1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F- 6-P)) and AMP in vitro, but this might has no significance in vivo
H0S67_RS05030	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
H0S67_RS05035	ENOG4105JNK	Glycosyl transferase (Group 1
H0S67_RS05040	ENOG4105CAQ	asparagine synthetase
H0S67_RS05110	ENOG4107W19	lmbE family
H0S67_RS05115	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
H0S67_RS05155	ENOG4108IY2	MazG family
H0S67_RS05165	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
H0S67_RS05230	ENOG4105E90	ABC transporter
H0S67_RS05235	ENOG4108IJ8	ABC transporter
H0S67_RS05240	ENOG4105E90	ABC transporter
H0S67_RS05245	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
H0S67_RS05255	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
H0S67_RS05260	ENOG4108JJ9	ABC, transporter
H0S67_RS05300	ENOG4105CJW	magnesium transporter
H0S67_RS05310	ENOG4105EET	magnesium chelatase
H0S67_RS05330	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
H0S67_RS05375	ENOG4105ETX	regulatoR
H0S67_RS05510	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
H0S67_RS05520	ENOG4105T1M	mycothiol conjugate amidase mca
H0S67_RS05540	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
H0S67_RS05550	ENOG4105FBN	Acid phosphatase
H0S67_RS05590	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H0S67_RS05595	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H0S67_RS05605	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
H0S67_RS05610	ENOG4105C7Z	Conserved Protein
H0S67_RS05630	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
H0S67_RS05650	ENOG4105C9Q	fumarate hydratase class II
H0S67_RS05750	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H0S67_RS05795	ENOG4105CPC	Aldo Keto reductase
H0S67_RS05815	ENOG4105CVK	Glutamate decarboxylase
H0S67_RS05840	ENOG4105BZU	Histidine kinase
H0S67_RS05845	ENOG4105BZU	Histidine kinase
H0S67_RS05850	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS05870	ENOG4105JFG	SpoIID LytB domain protein
H0S67_RS05880	ENOG4105CHP	RNA polymerase
H0S67_RS05905	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H0S67_RS05925	ENOG4105JFG	SpoIID LytB domain protein
H0S67_RS05935	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
H0S67_RS05975	ENOG4107WR6	Maf-like protein
H0S67_RS05995	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0S67_RS06005	ENOG4105D8K	carboxyl transferase
H0S67_RS06020	ENOG4108QER	Adenylate cyclase
H0S67_RS06025	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0S67_RS06040	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
H0S67_RS06045	ENOG4105K4P	CoA-binding domain protein
H0S67_RS06085	ENOG4108UKI	Enoyl-CoA hydratase
H0S67_RS06090	ENOG4108KGH	TRANSCRIPTIONal
H0S67_RS06120	ENOG4105NAU	thioesterase Superfamily protein
H0S67_RS06130	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
H0S67_RS06135	ENOG4108MKI	Glycosyl transferase, family 2
H0S67_RS06145	ENOG410602S	Transferase
H0S67_RS06150	ENOG4105MFV	ABC-2 type transporter
H0S67_RS06155	ENOG4105EY8	ABC transporter
H0S67_RS06195	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
H0S67_RS06220	ENOG4105W49	UPF0434 protein
H0S67_RS06230	ENOG4108TGC	Acyltransferase
H0S67_RS06240	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
H0S67_RS06245	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0S67_RS06250	ENOG4105BZU	Histidine kinase
H0S67_RS06255	ENOG4108T3R	lipoprotein lpqB
H0S67_RS06265	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
H0S67_RS06270	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS06275	ENOG4105T0Z	Conserved Protein
H0S67_RS06305	ENOG4108J59	Extracellular solute-binding protein, family 5
H0S67_RS06315	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
H0S67_RS06340	ENOG4105CBG	Sulfatase
H0S67_RS06345	ENOG4105E6M	Sulphatase-modifying factor protein
H0S67_RS06390	ENOG4105C1G	acyl-Coa dehydrogenase
H0S67_RS06410	ENOG4105F9F	transposase
H0S67_RS06435	ENOG4105DUX	Transporter
H0S67_RS06460	ENOG4105DB7	PHP domain protein
H0S67_RS06465	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
H0S67_RS06470	ENOG4105QIV	RNA polymerase
H0S67_RS06490	ENOG4107QJE	Chromosome Partitioning Protein
H0S67_RS06500	ENOG4105C1J	atp-dependent rna helicase
H0S67_RS06510	ENOG4105Y3U	Transglycosylase-associated protein
H0S67_RS06585	ENOG4107REC	cytoplasmic protein
H0S67_RS06590	ENOG4107R1Q	Membrane protein FdrA
H0S67_RS06605	ENOG4105C2W	permease
H0S67_RS06630	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H0S67_RS06645	ENOG4105E55	glycerol-3-phosphate acyltransferase
H0S67_RS06685	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H0S67_RS06725	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
H0S67_RS06785	ENOG4105DCG	PHP domain protein
H0S67_RS06815	ENOG41063PX	domain protein
H0S67_RS06825	ENOG4105DJZ	UPF0182 protein
H0S67_RS06985	ENOG4108M8W	Monooxygenase
H0S67_RS06995	ENOG4105C26	Dehydrogenase
H0S67_RS07000	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
H0S67_RS07025	ENOG4105DRR	Transcriptional regulator, GntR family
H0S67_RS07035	ENOG4107TTQ	Alpha beta hydrolase fold
H0S67_RS07070	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
H0S67_RS07095	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H0S67_RS07300	ENOG4105E2Z	phosphate ABC transporter (Permease
H0S67_RS07305	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
H0S67_RS07440	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H0S67_RS07460	ENOG4105BZU	Histidine kinase
H0S67_RS07465	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS07470	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H0S67_RS07490	ENOG4105DNP	FAD linked oxidase domain protein
H0S67_RS07535	ENOG4105BZU	Histidine kinase
H0S67_RS07540	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS07605	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
H0S67_RS07610	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
H0S67_RS07665	ENOG4108XG2	Histidine kinase
H0S67_RS07670	ENOG4107ZHV	Transcriptional regulator
H0S67_RS07710	ENOG4105C3M	thioredoxin reductase
H0S67_RS07715	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
H0S67_RS07720	ENOG4105NAF	rna polymerase sigma factor
H0S67_RS07730	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
H0S67_RS07750	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
H0S67_RS07760	ENOG4107R13	MMPL domain protein
H0S67_RS07815	ENOG4108JQ1	Dehydrogenase
H0S67_RS07830	ENOG4105D4Y	metalloprotease
H0S67_RS07855	ENOG4105C26	Dehydrogenase
H0S67_RS07880	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
H0S67_RS07900	ENOG4105C8Y	Acetylornithine aminotransferase
H0S67_RS07925	ENOG4105EJ5	oxidoreductase gamma subunit
H0S67_RS07930	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H0S67_RS07935	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS07950	ENOG4105CSV	Glutaminase
H0S67_RS07965	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
H0S67_RS08035	ENOG4105CJ1	ABC, transporter
H0S67_RS08040	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS08045	ENOG4105BZU	Histidine kinase
H0S67_RS08060	ENOG41068WN	
H0S67_RS08065	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
H0S67_RS08090	ENOG4105CQS	hydrogenase expression formation protein HypD
H0S67_RS08105	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H0S67_RS08110	ENOG4105VCT	ion-transport protein YfeO
H0S67_RS08115	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H0S67_RS08120	ENOG4105BZU	Histidine kinase
H0S67_RS08125	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
H0S67_RS08215	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H0S67_RS08265	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
H0S67_RS08270	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
H0S67_RS08315	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
H0S67_RS08320	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
H0S67_RS08330	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
H0S67_RS08405	ENOG410848D	S4 domain protein YaaA
H0S67_RS08420	ENOG4107TK4	histidinol-phosphate phosphatase
H0S67_RS08455	ENOG4108RAV	Conserved protein
H0S67_RS08465	ENOG4105EMN	RNA polymerase sigma factor
H0S67_RS08520	ENOG4108VEQ	Superoxide dismutase
H0S67_RS08535	ENOG4105CB2	alcohol dehydrogenase
H0S67_RS08590	ENOG4105C75	arginyL-tRNA synthetase
H0S67_RS08595	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
H0S67_RS08610	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
H0S67_RS08630	ENOG4107QJZ	Glycosyl transferase, family 2
H0S67_RS08635	ENOG4105VFB	Binds the 23S rRNA (By similarity)
H0S67_RS08640	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
H0S67_RS08655	ENOG4105ESV	Glycosyl transferase, family 4
H0S67_RS08670	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
H0S67_RS08680	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
H0S67_RS08685	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H0S67_RS08690	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
H0S67_RS08695	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
H0S67_RS08700	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
H0S67_RS08705	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
H0S67_RS08730	ENOG4106UW1	Major Facilitator superfamily
H0S67_RS08740	ENOG4105CDA	abc transporter atp-binding protein
H0S67_RS08745	ENOG4105EAD	ABC transporter
H0S67_RS08750	ENOG4105CT1	(ABC) transporter
H0S67_RS08800	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
H0S67_RS08805	ENOG4105XYF	acetyltransferase
H0S67_RS08810	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
H0S67_RS08895	ENOG4105CHU	acetyl-coa acetyltransferase
H0S67_RS08930	ENOG4105K56	Transcriptional regulator
H0S67_RS08970	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
H0S67_RS08990	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
H0S67_RS09020	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
H0S67_RS09030	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
H0S67_RS09035	ENOG4108V9W	transcriptional regulatory protein
H0S67_RS09060	ENOG4105C10	Electron transfer flavoprotein
H0S67_RS09090	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
H0S67_RS09095	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H0S67_RS09135	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H0S67_RS09145	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
H0S67_RS09160	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
H0S67_RS09175	ENOG4105C7K	acetolactate synthase
H0S67_RS09180	ENOG4105EXC	Acyl-transferase
H0S67_RS09185	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
H0S67_RS09235	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
H0S67_RS09240	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H0S67_RS09260	ENOG4107TXC	Transcriptional regulator
H0S67_RS09285	ENOG4105NAF	rna polymerase sigma factor
H0S67_RS09290	ENOG4107YU2	histidine triad (hIT) protein
H0S67_RS09315	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
H0S67_RS09380	ENOG4108UW5	maltose o-acetyltransferase
H0S67_RS09390	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
H0S67_RS09400	ENOG4108J2P	Alpha beta hydrolase fold
H0S67_RS09405	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
H0S67_RS09420	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
H0S67_RS09440	ENOG4105DIK	(ABC) transporter
H0S67_RS09520	ENOG4107W19	lmbE family
H0S67_RS09615	ENOG4105I6B	RNA polymerase
H0S67_RS09645	ENOG4105GR3	Histidine kinase
H0S67_RS09650	ENOG4105CEY	Amp-dependent synthetase and ligase
H0S67_RS09715	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H0S67_RS09735	ENOG4105MHT	Transcriptional regulator, ARSR family
H0S67_RS09815	ENOG4105BZU	Histidine kinase
H0S67_RS09825	ENOG4108M15	ABC transporter
H0S67_RS09830	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
H0S67_RS09835	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
H0S67_RS09865	ENOG4105C5F	glutamine synthetase
H0S67_RS09880	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
H0S67_RS09895	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
H0S67_RS09930	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
H0S67_RS09950	ENOG4105D78	K07001 NTE family protein
H0S67_RS09980	ENOG4105W8D	rdd domain containing protein
H0S67_RS10000	ENOG4105CKU	formyltetrahydrofolate synthetase
H0S67_RS10030	ENOG4105DQ4	alcohol dehydrogenase
H0S67_RS10055	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS10070	ENOG4105BZP	glycoside hydrolase 15-related
H0S67_RS10095	ENOG4105E6M	Sulphatase-modifying factor protein
H0S67_RS10100	ENOG41061MV	Arylsulfatase
H0S67_RS10130	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS10135	ENOG4105BZU	Histidine kinase
H0S67_RS10140	ENOG4105CJ1	ABC, transporter
H0S67_RS10150	ENOG4107TE5	Lipid kinase
H0S67_RS10225	ENOG41061ZR	Transcriptional regulator
H0S67_RS10225	ENOG41061ZR	Transcriptional regulator
H0S67_RS10250	ENOG4105C5B	carbamate kinase
H0S67_RS10260	ENOG4105CEU	Arginine dihydrolase
H0S67_RS10265	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
H0S67_RS10275	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
H0S67_RS10280	ENOG4105DSF	transport protein
H0S67_RS10305	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
H0S67_RS10410	ENOG4105CJ1	ABC, transporter
H0S67_RS10490	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
H0S67_RS10515	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
H0S67_RS10525	ENOG4105EPW	hflc protein
H0S67_RS10535	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H0S67_RS10540	ENOG4105CN5	Metallo-Beta-Lactamase
H0S67_RS10570	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
H0S67_RS10585	ENOG4105BZP	glycoside hydrolase 15-related
H0S67_RS10590	ENOG41062D9	Histidine kinase
H0S67_RS10595	ENOG4105ETX	regulatoR
H0S67_RS10600	ENOG4105CEV	competence damage-inducible protein
H0S67_RS10610	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
H0S67_RS10615	ENOG4107QRT	dEAD DEAH box helicase
H0S67_RS10620	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H0S67_RS10630	ENOG4105DEF	Extracellular solute-binding protein, family 5
H0S67_RS10635	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H0S67_RS10645	ENOG4105C3U	ABC transporter
H0S67_RS10650	ENOG4108JQ7	(ABC) transporter
H0S67_RS10655	ENOG4105DVW	rieske (2Fe-2S)
H0S67_RS10665	ENOG4105DVW	rieske (2Fe-2S)
H0S67_RS10710	ENOG4105EYF	MMPL domain protein
H0S67_RS10715	ENOG4105VRS	hydrolase family 18
H0S67_RS10730	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H0S67_RS10740	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
H0S67_RS10770	ENOG4105CHU	acetyl-coa acetyltransferase
H0S67_RS10805	ENOG4107TPY	serine threonine protein kinase
H0S67_RS10875	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
H0S67_RS10885	ENOG4108KK1	membrane protein AbrB duplication
H0S67_RS10920	ENOG4105CAY	ferredoxin--nadp reductase
H0S67_RS10930	ENOG4108SGK	Tetr family transcriptional regulator
H0S67_RS10965	ENOG4105CSR	polyphosphate kinase 2
H0S67_RS10980	ENOG4105H3G	oxidoreductase
H0S67_RS11030	ENOG4105MXW	flavin reductase domain protein, FMN-binding
H0S67_RS11085	ENOG4105CPC	Aldo Keto reductase
H0S67_RS11090	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H0S67_RS11095	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H0S67_RS11105	ENOG4105DYW	oxidoreductase
H0S67_RS11150	ENOG4105C5X	domain protein
H0S67_RS11160	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H0S67_RS11180	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
H0S67_RS11190	ENOG4105CIE	May be required for sporulation (By similarity)
H0S67_RS11195	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
H0S67_RS11200	ENOG4105BZA	Phosphoglycerate kinase
H0S67_RS11205	ENOG4105CP7	Triose-phosphate isomerase
H0S67_RS11225	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
H0S67_RS11235	ENOG4107QYV	phosphohexose isomerase
H0S67_RS11240	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
H0S67_RS11250	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
H0S67_RS11310	ENOG4105C3K	feS assembly ATPase SufC
H0S67_RS11315	ENOG4105C9B	Cysteine desulfurase
H0S67_RS11320	ENOG4108UNV	SUF system FeS assembly protein, NifU family
H0S67_RS11325	ENOG4105VG1	fes assembly suf system protein
H0S67_RS11330	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H0S67_RS11340	ENOG4105CIG	ABC transporter
H0S67_RS11345	ENOG4105DIM	ABC transporter
H0S67_RS11370	ENOG4105BZ1	(ABC) transporter
H0S67_RS11400	ENOG4105WKW	Pfam:DUF1458
H0S67_RS11405	ENOG4105CHR	reductase
H0S67_RS11495	ENOG4108Z86	Glutamine amidotransferase
H0S67_RS11500	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
H0S67_RS11545	ENOG4105CJ1	ABC, transporter
H0S67_RS11555	ENOG4105CH6	catalase
H0S67_RS11590	ENOG4108UZX	fmn reductase
H0S67_RS11595	ENOG4108V1U	phospholipid-binding protein
H0S67_RS11600	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
H0S67_RS11630	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H0S67_RS11635	ENOG4105C1G	acyl-Coa dehydrogenase
H0S67_RS11675	ENOG4105JXB	ankyrin repeat-containing protein
H0S67_RS11680	ENOG4105ERX	Dehydrogenase
H0S67_RS11685	ENOG4105C94	Transporter
H0S67_RS11725	ENOG41088YS	Glycosyl transferase (Group 1
H0S67_RS11755	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
H0S67_RS11765	ENOG4108U3T	pfkb domain protein
H0S67_RS11775	ENOG4105E3J	oxidoreductase
H0S67_RS11790	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H0S67_RS11810	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
H0S67_RS11815	ENOG4105D7N	magnesium and cobalt transport protein CorA
H0S67_RS11840	ENOG4105C8N	cysteinyl-tRNA synthetase
H0S67_RS11855	ENOG4107URF	beta-phospho-glucomutase
H0S67_RS11870	ENOG4105BZU	Histidine kinase
H0S67_RS11875	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS11895	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
H0S67_RS11915	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H0S67_RS11920	ENOG4105E5F	proteasome
H0S67_RS11925	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
H0S67_RS11930	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
H0S67_RS11935	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
H0S67_RS11945	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
H0S67_RS11950	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
H0S67_RS11965	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
H0S67_RS11970	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
H0S67_RS12020	ENOG4105FRY	Dehydrogenase
H0S67_RS12025	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
H0S67_RS12030	ENOG4107CHF	5,6-aminomutase beta subunit
H0S67_RS12035	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
H0S67_RS12050	ENOG4105FS0	cytoplasmic membrane protein
H0S67_RS12055	ENOG4105Q70	
H0S67_RS12095	ENOG4105DFH	Transport of potassium into the cell (By similarity)
H0S67_RS12125	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H0S67_RS12130	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H0S67_RS12185	ENOG4107RT4	flavin reductase domain protein
H0S67_RS12200	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
H0S67_RS12220	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
H0S67_RS12225	ENOG4107RH8	nuclease SbcCD subunit D
H0S67_RS12230	ENOG4105EYH	Exonuclease
H0S67_RS12240	ENOG4105EYH	Exonuclease
H0S67_RS12310	ENOG4108UW8	fha domain-containing protein
H0S67_RS12385	ENOG4105K63	Thioredoxin
H0S67_RS12390	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H0S67_RS12465	ENOG4105F9F	transposase
H0S67_RS12500	ENOG4105F9F	transposase
H0S67_RS12545	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS12565	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
H0S67_RS12610	ENOG4105CGH	5'-nucleotidase
H0S67_RS12655	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
H0S67_RS12720	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS12760	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
H0S67_RS12770	ENOG4105CAT	Cytidine monophosphate kinase
H0S67_RS12790	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
H0S67_RS12825	ENOG4108YZ4	nudix hydrolase
H0S67_RS12835	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
H0S67_RS12860	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
H0S67_RS12865	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
H0S67_RS12880	ENOG4105DSU	hydrolase
H0S67_RS12910	ENOG4108VX5	3-methyladenine DNA glycosylase
H0S67_RS12915	ENOG4105CH7	arginosuccinase
H0S67_RS12925	ENOG4108Z4K	mutator MutT protein
H0S67_RS12930	ENOG4105CDH	Citrulline--aspartate ligase
H0S67_RS12935	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
H0S67_RS12940	ENOG4105DBV	ornithine carbamoyltransferase
H0S67_RS12945	ENOG4105C8Y	Acetylornithine aminotransferase
H0S67_RS12950	ENOG4105CAS	nag kinase
H0S67_RS12955	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
H0S67_RS12965	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
H0S67_RS12975	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
H0S67_RS12980	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
H0S67_RS12995	ENOG4108RWN	rrna methyltransferase
H0S67_RS13000	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
H0S67_RS13005	ENOG41084BS	50S ribosomal protein L35
H0S67_RS13025	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
H0S67_RS13035	ENOG4105GVF	(ABC) transporter
H0S67_RS13045	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
H0S67_RS13065	ENOG4107WI4	Aldose-1-epimerase
H0S67_RS13075	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
H0S67_RS13080	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
H0S67_RS13085	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
H0S67_RS13090	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
H0S67_RS13140	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
H0S67_RS13145	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H0S67_RS13155	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
H0S67_RS13185	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
H0S67_RS13190	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
H0S67_RS13195	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
H0S67_RS13230	ENOG4105CD3	dihydroorotase
H0S67_RS13235	ENOG4105CXT	aspartate transcarbamylase
H0S67_RS13240	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
H0S67_RS13285	ENOG4107QN2	dihydrolipoyl dehydrogenase
H0S67_RS13290	ENOG410803B	Involved in the transcription termination process (By similarity)
H0S67_RS13295	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
H0S67_RS13305	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
H0S67_RS13310	ENOG4105D49	3-dehydroquinate synthase
H0S67_RS13315	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
H0S67_RS13320	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
H0S67_RS13335	ENOG4105HHA	aminodeoxychorismate lyase
H0S67_RS13345	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
H0S67_RS13360	ENOG4108JQ7	(ABC) transporter
H0S67_RS13380	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H0S67_RS13385	ENOG4105C9M	aspartyl-trna synthetase
H0S67_RS13410	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
H0S67_RS13415	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H0S67_RS13425	ENOG4105VIE	preprotein translocase, subunit YajC
H0S67_RS13430	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
H0S67_RS13435	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
H0S67_RS13440	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
H0S67_RS13450	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
H0S67_RS13480	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
H0S67_RS13500	ENOG4105ECY	inositol monophosphatase
H0S67_RS13510	ENOG4105K5X	acetyltransferase
H0S67_RS13540	ENOG4105KF0	sporulation and cell division protein, SsgA
H0S67_RS13570	ENOG4105DQE	DNA ligase
H0S67_RS13600	ENOG4105CMR	udp-glucose 4-epimerase
H0S67_RS13605	ENOG4108IAJ	Nad-dependent epimerase dehydratase
H0S67_RS13610	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
H0S67_RS13620	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
H0S67_RS13630	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
H0S67_RS13670	ENOG4107QJT	sodium dicarboxylate symporter
H0S67_RS13695	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
H0S67_RS13700	ENOG4105K8R	UPF0145 protein
H0S67_RS13740	ENOG4105CSR	polyphosphate kinase 2
H0S67_RS13760	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
H0S67_RS13765	ENOG4105BZU	Histidine kinase
H0S67_RS13785	ENOG4108D32	Methyltransferase
H0S67_RS13805	ENOG4105CMR	udp-glucose 4-epimerase
H0S67_RS13810	ENOG4107USC	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
H0S67_RS13815	ENOG4108HH4	Major Facilitator Superfamily
H0S67_RS13840	ENOG4105HAC	ABC-2 type transporter
H0S67_RS13845	ENOG4105CJ1	ABC, transporter
H0S67_RS13865	ENOG4105EUJ	GTP cyclohydrolase i
H0S67_RS13890	ENOG4105NAF	rna polymerase sigma factor
H0S67_RS13910	ENOG4107QM5	aconitate hydratase
H0S67_RS13920	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H0S67_RS13925	ENOG4105C0X	amino acid
H0S67_RS13930	ENOG4107VEG	TrkA-N domain protein
H0S67_RS13955	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
H0S67_RS13980	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
H0S67_RS14010	ENOG4105EN6	Membrane
H0S67_RS14045	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
H0S67_RS14060	ENOG4107UWP	Major facilitator superfamily MFS_1
H0S67_RS14105	ENOG41067HS	methyltransferase
H0S67_RS14115	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
H0S67_RS14120	ENOG4105D1K	glutamate--cysteine ligase
H0S67_RS14165	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H0S67_RS14180	ENOG4105SHT	UspA domain-containing protein
H0S67_RS14195	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
H0S67_RS14200	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
H0S67_RS14210	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
H0S67_RS14235	ENOG4105E7W	lamb ycsf family protein
H0S67_RS14250	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
H0S67_RS14355	ENOG41073B4	coagulation factor 5 8 type domain-containing protein
H0S67_RS14360	ENOG41073B4	coagulation factor 5 8 type domain-containing protein
H0S67_RS14365	ENOG4108M6P	methyltransferase
H0S67_RS14370	ENOG4108I69	Glycosyl transferases group 1
H0S67_RS14390	ENOG4108RG3	short-chain dehydrogenase reductase
H0S67_RS14435	ENOG4108IV0	ABC, transporter
H0S67_RS14440	ENOG4105C0Z	ABC transporter
H0S67_RS14455	ENOG4105C32	Amino acid ABC transporter (Permease)
H0S67_RS14490	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
H0S67_RS14500	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
H0S67_RS14505	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
H0S67_RS14510	ENOG4105DK0	Indole-3-glycerol phosphate synthase
H0S67_RS14530	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
H0S67_RS14540	ENOG4105BZ1	(ABC) transporter
H0S67_RS14565	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
H0S67_RS14570	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
H0S67_RS14580	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
H0S67_RS14585	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
H0S67_RS14590	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H0S67_RS14595	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
H0S67_RS14605	ENOG4108Z66	YbaK ebsC protein
H0S67_RS14620	ENOG4105C0B	DNA polymerase III (alpha subunit)
H0S67_RS14640	ENOG4105NHS	Transcriptional regulator, TraR DksA family
H0S67_RS14655	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
H0S67_RS14665	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
H0S67_RS14670	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
H0S67_RS14680	ENOG4105DFU	Cell wall formation (By similarity)
H0S67_RS14685	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
H0S67_RS14695	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
H0S67_RS14700	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
H0S67_RS14710	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
H0S67_RS14725	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
H0S67_RS14730	ENOG4108V6E	Cell division protein mraZ
H0S67_RS14735	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H0S67_RS14765	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
H0S67_RS14780	ENOG4105C0B	DNA polymerase III (alpha subunit)
H0S67_RS14785	ENOG4105C0B	DNA polymerase III (alpha subunit)
H0S67_RS14790	ENOG4105C0B	DNA polymerase III (alpha subunit)
H0S67_RS14830	ENOG4107VFM	Dehydrogenase
H0S67_RS14860	ENOG4105KYH	transcriptional regulatory protein
H0S67_RS14875	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
H0S67_RS14900	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
H0S67_RS14920	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS14950	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS14985	ENOG4105DKQ	ROK family
H0S67_RS14990	ENOG4105DKQ	ROK family
H0S67_RS15010	ENOG4108IQE	Amp-dependent synthetase and ligase
H0S67_RS15015	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
H0S67_RS15080	ENOG4105CCU	oxidase (Subunit III)
H0S67_RS15090	ENOG4107EUI	c reductase, iron-sulfur
H0S67_RS15095	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H0S67_RS15100	ENOG4107UBC	ErfK ybiS ycfS ynhG family protein
H0S67_RS15105	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
H0S67_RS15110	ENOG4105BZ9	Cytochrome C oxidase, subunit I
H0S67_RS15115	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
H0S67_RS15125	ENOG4105VFE	sira family
H0S67_RS15130	ENOG4107T4Z	adenosine kinase
H0S67_RS15155	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
H0S67_RS15160	ENOG4105BZU	Histidine kinase
H0S67_RS15170	ENOG4105D0M	Protease HtpX homolog
H0S67_RS15190	ENOG4105CPC	Aldo Keto reductase
H0S67_RS15215	ENOG4105CTS	PTS system mannitol-specific
H0S67_RS15220	ENOG4105CPQ	Dehydrogenase
H0S67_RS15250	ENOG4105C1V	Peptidase, M16
H0S67_RS15260	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
H0S67_RS15270	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
H0S67_RS15280	ENOG410804X	Transcriptional regulator
H0S67_RS15285	ENOG4105DE4	1-phosphofructokinase
H0S67_RS15295	ENOG4105KZ7	phosphocarrier protein hpr
H0S67_RS15360	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
H0S67_RS15405	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
H0S67_RS15410	ENOG4105DZP	Membrane-associated zinc metalloprotease
H0S67_RS15425	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
H0S67_RS15430	ENOG4105D81	ABC transporter, permease
H0S67_RS15435	ENOG4107TYH	extracellular solute-binding protein family 1
H0S67_RS15440	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H0S67_RS15460	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
H0S67_RS15465	ENOG4105D38	putrescine abc transporter
H0S67_RS15470	ENOG4105F38	ABC transporter, permease
H0S67_RS15475	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H0S67_RS15505	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
H0S67_RS15530	ENOG41066VF	YeeE YedE family protein
H0S67_RS15550	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
H0S67_RS15570	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
H0S67_RS15575	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
H0S67_RS15590	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
H0S67_RS15595	ENOG4105CE9	30S ribosomal protein S2
H0S67_RS15605	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H0S67_RS15620	ENOG41080R2	UPF0102 protein
H0S67_RS15635	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H0S67_RS15645	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
H0S67_RS15650	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
H0S67_RS15655	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
H0S67_RS15660	ENOG41082KU	UPF0109 protein
H0S67_RS15665	ENOG4105K5M	30s ribosomal protein S16
H0S67_RS15675	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS15680	ENOG4105BZU	Histidine kinase
H0S67_RS15705	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
H0S67_RS15710	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
H0S67_RS15785	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
H0S67_RS15790	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
H0S67_RS15805	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
H0S67_RS15810	ENOG4106H78	methyltransferase
H0S67_RS15820	ENOG4105DP4	dak2 domain fusion protein ylov
H0S67_RS15825	ENOG4105VB9	50S ribosomal protein l28
H0S67_RS15845	ENOG4105CPF	Cell wall formation (By similarity)
H0S67_RS15855	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
H0S67_RS15870	ENOG4105K70	DNA-binding protein
H0S67_RS15875	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H0S67_RS15880	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H0S67_RS15890	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
H0S67_RS15900	ENOG4108KGH	TRANSCRIPTIONal
H0S67_RS15920	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
H0S67_RS15925	ENOG4105ERH	Fumarylacetoacetate hydrolase
H0S67_RS15935	ENOG4105DR5	peptidase
H0S67_RS15955	ENOG4107ZYJ	bioY protein
H0S67_RS15960	ENOG4108JJB	ABC transporter
H0S67_RS15965	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
H0S67_RS15975	ENOG4108YYH	Nadph-dependent fmn reductase
H0S67_RS15990	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
H0S67_RS16000	ENOG4105CM2	brancheD-chain amino acid aminotransferase
H0S67_RS16005	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H0S67_RS16020	ENOG4108VW9	Membrane
H0S67_RS16065	ENOG4107ZXU	DSBA oxidoreductase
H0S67_RS16070	ENOG4107QTZ	amino acid
H0S67_RS16075	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
H0S67_RS16080	ENOG4108ZP8	Acetolactate synthase small subunit
H0S67_RS16115	ENOG4105ME7	Membrane
H0S67_RS16180	ENOG4105BZ1	(ABC) transporter
H0S67_RS16200	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H0S67_RS16205	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H0S67_RS16270	ENOG4107R7Y	intracellular protease Pfpi family
H0S67_RS16280	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
H0S67_RS16305	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H0S67_RS16310	ENOG4105K46	50S ribosomal protein l27
H0S67_RS16315	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
H0S67_RS16320	ENOG4105C03	ribonuclease
H0S67_RS16340	ENOG4105DJ2	Major Facilitator Superfamily
H0S67_RS16380	ENOG4105CNI	cell division protein FtsW
H0S67_RS16400	ENOG4105DFF	Rod shape-determining protein mreb
H0S67_RS16405	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
H0S67_RS16425	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H0S67_RS16440	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
H0S67_RS16450	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
H0S67_RS16455	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H0S67_RS16460	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H0S67_RS16495	ENOG4108YZG	isomerase
H0S67_RS16515	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
H0S67_RS16530	ENOG4105MC2	DSBA oxidoreductase
H0S67_RS16555	ENOG4105D8X	mechanosensitive ion channel
H0S67_RS16565	ENOG4108Z18	K06886 hemoglobin
H0S67_RS16585	ENOG4108TGP	Thioesterase superfamily protein
H0S67_RS16615	ENOG4107YH6	single-stranded DNA-binding protein
H0S67_RS16635	ENOG4107T6F	Xaa-Pro aminopeptidase
H0S67_RS16640	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
H0S67_RS16645	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS16665	ENOG4105C57	major facilitator superfamily
H0S67_RS16705	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
H0S67_RS16720	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
H0S67_RS16735	ENOG410630Q	Methylamine utilization
H0S67_RS16760	ENOG4105EUB	pirin domain protein
H0S67_RS16765	ENOG4105BZU	Histidine kinase
H0S67_RS16785	ENOG4105BZU	Histidine kinase
H0S67_RS16800	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
H0S67_RS16815	ENOG4107U9T	Pfam:Ribonuclease_BN
H0S67_RS16840	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
H0S67_RS16865	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
H0S67_RS16870	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
H0S67_RS16880	ENOG4105CJ1	ABC, transporter
H0S67_RS16885	ENOG4105ENE	Histidine kinase
H0S67_RS16890	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS16900	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
H0S67_RS16905	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
H0S67_RS16935	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
H0S67_RS16945	ENOG4108RWI	nicotinamidase
H0S67_RS16975	ENOG4105DXB	Major Facilitator superfamily
H0S67_RS16980	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
H0S67_RS16990	ENOG4108FUF	Transcriptional regulator, IclR family
H0S67_RS17005	ENOG4108UJU	UPF0301 protein
H0S67_RS17020	ENOG4108R5T	secreted protein
H0S67_RS17030	ENOG4105CHR	reductase
H0S67_RS17060	ENOG4105T0Z	Conserved Protein
H0S67_RS17090	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
H0S67_RS17110	ENOG4105ETX	regulatoR
H0S67_RS17115	ENOG4105BZU	Histidine kinase
H0S67_RS17120	ENOG4105C08	Histidine kinase
H0S67_RS17140	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
H0S67_RS17155	ENOG4105CAK	Cell division ATP-binding protein ftsE
H0S67_RS17390	ENOG4105EYF	MMPL domain protein
H0S67_RS17395	ENOG41079KZ	Major Facilitator Superfamily
H0S67_RS17455	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
H0S67_RS17470	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS17480	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS17485	ENOG4105D3Q	Sugar transferase
H0S67_RS17495	ENOG4105ETX	regulatoR
H0S67_RS17515	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
H0S67_RS17520	ENOG4105FDF	Could be involved in DNA repair (By similarity)
H0S67_RS17525	ENOG4105PDP	Short chain dehydrogenase
H0S67_RS17535	ENOG4105BZ1	(ABC) transporter
H0S67_RS17555	ENOG4105C7I	Dehydrogenase
H0S67_RS17560	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
H0S67_RS17575	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H0S67_RS17625	ENOG4105C0H	protease
H0S67_RS17635	ENOG4105DU6	RNA polymerase
H0S67_RS17650	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
H0S67_RS17665	ENOG4108UKI	Enoyl-CoA hydratase
H0S67_RS17690	ENOG4108URH	decarboxylase
H0S67_RS17705	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
H0S67_RS17750	ENOG4105C5S	asparaginyl-tRNA synthetase
H0S67_RS17775	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
H0S67_RS17795	ENOG4105VG5	Membrane
H0S67_RS17800	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
H0S67_RS17805	ENOG4105CEU	Arginine dihydrolase
H0S67_RS17810	ENOG4105DBV	ornithine carbamoyltransferase
H0S67_RS17815	ENOG4105CB2	alcohol dehydrogenase
H0S67_RS17840	ENOG4107TPY	serine threonine protein kinase
H0S67_RS17845	ENOG4105BZU	Histidine kinase
H0S67_RS17850	ENOG4105BZU	Histidine kinase
H0S67_RS17860	ENOG4105BZU	Histidine kinase
H0S67_RS17875	ENOG4105BZU	Histidine kinase
H0S67_RS17910	ENOG4105CZX	twitching motility protein
H0S67_RS17920	ENOG4107QHF	type ii secretion system protein e
H0S67_RS17975	ENOG4105KHS	type IV fimbrial pilin protein
H0S67_RS17990	ENOG4105FRN	stage II sporulation protein
H0S67_RS17995	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H0S67_RS18100	ENOG4105NHS	Transcriptional regulator, TraR DksA family
H0S67_RS18110	ENOG4105CGK	Exodeoxyribonuclease III
H0S67_RS18155	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
H0S67_RS18175	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
H0S67_RS18185	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
H0S67_RS18190	ENOG4105C26	Dehydrogenase
H0S67_RS18210	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
H0S67_RS18255	ENOG4107RM1	amidohydrolase
H0S67_RS18300	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
H0S67_RS18310	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
H0S67_RS18335	ENOG4105E33	succinate dehydrogenase
H0S67_RS18345	ENOG4107H3J	ribonuclease
H0S67_RS18355	ENOG4105C31	Tryptophanyl-tRNA synthetase
H0S67_RS18360	ENOG4105DNP	FAD linked oxidase domain protein
H0S67_RS18370	ENOG4105F27	Major Facilitator
H0S67_RS18380	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
H0S67_RS18400	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
H0S67_RS18410	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
H0S67_RS18475	ENOG4107RR1	TRANSCRIPTIONal
H0S67_RS18490	ENOG4105D9G	High-affinity
H0S67_RS18500	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS18525	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
H0S67_RS18605	ENOG4105BZ1	(ABC) transporter
H0S67_RS18610	ENOG4105BZ1	(ABC) transporter
H0S67_RS18615	ENOG4105DYW	oxidoreductase
H0S67_RS18620	ENOG4105C1G	acyl-Coa dehydrogenase
H0S67_RS18655	ENOG4108HWW	ABC transporter
H0S67_RS18660	ENOG4105C2J	ABC transporter
H0S67_RS18665	ENOG4105DFW	ABC transporter
H0S67_RS18685	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H0S67_RS18695	ENOG4105C26	Dehydrogenase
H0S67_RS18700	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
H0S67_RS18710	ENOG4107QVP	Dehydrogenase
H0S67_RS18715	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H0S67_RS18730	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
H0S67_RS18745	ENOG4107VMB	Beta-lactamase domain protein
H0S67_RS18755	ENOG4105NAF	rna polymerase sigma factor
H0S67_RS18765	ENOG4105FQP	Beta-lactamase
H0S67_RS18770	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H0S67_RS18790	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
H0S67_RS18805	ENOG4105F2Z	3-oxoadipate enol-lactonase
H0S67_RS18810	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
H0S67_RS18825	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
H0S67_RS18830	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
H0S67_RS18835	ENOG4105CS9	pantothenic acid kinase
H0S67_RS18850	ENOG4108UJD	30S ribosomal protein S9
H0S67_RS18855	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
H0S67_RS18895	ENOG4105C0H	protease
H0S67_RS18970	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H0S67_RS18995	ENOG4105CHR	reductase
H0S67_RS19015	ENOG41085W3	Transposase
H0S67_RS19070	ENOG4105NAF	rna polymerase sigma factor
H0S67_RS19080	ENOG4107SM8	Adenylate Guanylate cyclase
H0S67_RS19085	ENOG4105F9F	transposase
H0S67_RS19100	ENOG4105CPC	Aldo Keto reductase
H0S67_RS19105	ENOG4105HS2	Arsenate reductase
H0S67_RS19115	ENOG41082BM	Transcriptional regulator, arsr family
H0S67_RS19125	ENOG4107Y49	methyltransferase
H0S67_RS19130	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
H0S67_RS19140	ENOG4105EDK	PfkB domain protein
H0S67_RS19150	ENOG4108ZT0	50S ribosomal protein l17
H0S67_RS19155	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H0S67_RS19160	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
H0S67_RS19165	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
H0S67_RS19170	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H0S67_RS19175	ENOG41067V7	50S ribosomal protein L36
H0S67_RS19180	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
H0S67_RS19185	ENOG4105DEN	Luciferase family
H0S67_RS19200	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
H0S67_RS19210	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
H0S67_RS19215	ENOG410849U	50S ribosomal protein L30
H0S67_RS19220	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
H0S67_RS19225	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
H0S67_RS19230	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
H0S67_RS19235	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
H0S67_RS19240	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
H0S67_RS19245	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H0S67_RS19250	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
H0S67_RS19255	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
H0S67_RS19260	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
H0S67_RS19265	ENOG41082SA	50s ribosomal protein l29
H0S67_RS19270	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
H0S67_RS19275	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
H0S67_RS19280	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
H0S67_RS19290	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H0S67_RS19295	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
H0S67_RS19300	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
H0S67_RS19305	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
H0S67_RS19325	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H0S67_RS19380	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
H0S67_RS19390	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
H0S67_RS19395	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
H0S67_RS19400	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
H0S67_RS19415	ENOG4105C7N	Xanthine uracil vitamin C permease
H0S67_RS19435	ENOG4105VEQ	Cold shock protein
H0S67_RS19460	ENOG4105NAF	rna polymerase sigma factor
H0S67_RS19540	ENOG4106JDR	secreted
H0S67_RS19550	ENOG4105EEM	helicase
H0S67_RS19575	ENOG4105FDP	GntR family transcriptional regulator
H0S67_RS19580	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
H0S67_RS19585	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H0S67_RS19600	ENOG4107QK5	Homocysteine s-methyltransferase
H0S67_RS19680	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H0S67_RS19690	ENOG4105F9F	transposase
H0S67_RS19730	ENOG4105GRZ	Ycii-related protein
H0S67_RS19735	ENOG4105CHP	RNA polymerase
H0S67_RS19775	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
H0S67_RS19800	ENOG4105W1N	transcriptional regulator
H0S67_RS19815	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
H0S67_RS19835	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
H0S67_RS19875	ENOG4108Z4X	TRANSCRIPTIONal
H0S67_RS19885	ENOG4105C1G	acyl-Coa dehydrogenase
H0S67_RS19900	ENOG4105C8N	cysteinyl-tRNA synthetase
H0S67_RS19910	ENOG4105CHR	reductase
H0S67_RS19920	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
H0S67_RS19925	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
H0S67_RS19940	ENOG4107QZF	nitrite reductase NADPH large subunit
H0S67_RS19955	ENOG4105DQQ	Major facilitator superfamily MFS_1
H0S67_RS19970	ENOG4108VJ1	Transcriptional regulator (CarD family
H0S67_RS19990	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H0S67_RS20000	ENOG4105BZU	Histidine kinase
H0S67_RS20005	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H0S67_RS20010	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
H0S67_RS20025	ENOG4108YZJ	Pfam:DUF2596
H0S67_RS20030	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
H0S67_RS20050	ENOG4105D4Y	metalloprotease
H0S67_RS20065	ENOG4105CI3	gtp-binding protein typa
H0S67_RS20130	ENOG4105WH1	Two component transcriptional regulator luxr family
H0S67_RS20180	ENOG4105EEI	dihydropteroate synthase
H0S67_RS20265	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
H0S67_RS20270	ENOG4108QV3	biosynthesis protein
H0S67_RS20300	ENOG4107RIQ	Sulfate adenylate transferase
H0S67_RS20305	ENOG4107TSN	permease
H0S67_RS20320	ENOG4105EIP	mannose-6-phosphate isomerase
H0S67_RS20325	ENOG4105C30	Nad-dependent epimerase dehydratase
H0S67_RS20330	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
H0S67_RS20335	ENOG4106CD9	glycosyl transferase group 1
H0S67_RS20345	ENOG4105Q84	sucrose synthase
H0S67_RS20370	ENOG41090R7	Ferric uptake
H0S67_RS20375	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
H0S67_RS20405	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
H0S67_RS20410	ENOG4105PKJ	carbohydrate binding
H0S67_RS20415	ENOG4105KHC	sulfurtransferase
H0S67_RS20425	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
H0S67_RS20455	ENOG4107NHD	transcriptional regulator
H0S67_RS20460	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
H0S67_RS20480	ENOG4105CPQ	Dehydrogenase
H0S67_RS20500	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
H0S67_RS20510	ENOG4105CJ3	phosphate transporter
H0S67_RS20515	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H0S67_RS20530	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
H0S67_RS20555	ENOG4105VPX	protein, conserved in bacteria
H0S67_RS20565	ENOG4105VEQ	Cold shock protein
H0S67_RS20570	ENOG4105EXC	Acyl-transferase
H0S67_RS20605	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
H0S67_RS20610	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
H0S67_RS20630	ENOG4105VT2	5-hydroxyisourate hydrolase
H0S67_RS20735	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
H0S67_RS20765	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
H0S67_RS20780	ENOG4107ETC	gas vesicle protein
H0S67_RS20795	ENOG4105CEP	NADH dehydrogenase
H0S67_RS20805	ENOG4105WMR	Protein CrcB homolog
H0S67_RS20810	ENOG41084I6	Protein CrcB homolog
H0S67_RS20905	ENOG4105CMG	Carbohydrate kinase
H0S67_RS20920	ENOG4105BZU	Histidine kinase
H0S67_RS20950	ENOG4105BZU	Histidine kinase
H0S67_RS20990	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
H0S67_RS21015	ENOG4105XEA	Tetr family transcriptional regulator
H0S67_RS21035	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
H0S67_RS21040	ENOG410839H	phosphoribosylformylglycinamidine synthase
H0S67_RS21060	ENOG4105EYF	MMPL domain protein
H0S67_RS21085	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
H0S67_RS21095	ENOG4105C83	adenylosuccinate lyase
H0S67_RS21100	ENOG4105C12	Phosphoribosylglycinamide synthetase
H0S67_RS21105	ENOG4107VGR	Catalase
H0S67_RS21110	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
H0S67_RS21115	ENOG4107TE5	Lipid kinase
H0S67_RS21140	ENOG4107RCW	fructose-bisphosphate aldolase
H0S67_RS21190	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
H0S67_RS21205	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H0S67_RS21225	ENOG4105DDN	Pentapeptide repeat-containing protein
H0S67_RS21235	ENOG4105KNI	merR family transcriptional Regulator
H0S67_RS21240	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H0S67_RS21245	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H0S67_RS21250	ENOG4105CFG	Acts as a chaperone (By similarity)
H0S67_RS21260	ENOG4108ZT1	Transcriptional regulator
H0S67_RS21265	ENOG4108KTG	Membrane protein, drug metabolite transporter
H0S67_RS21300	ENOG4105BZU	Histidine kinase
H0S67_RS21325	ENOG4107RBB	ABC transporter, permease
H0S67_RS21340	ENOG4105BZU	Histidine kinase
H0S67_RS21365	ENOG4107SM8	Adenylate Guanylate cyclase
H0S67_RS21390	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
H0S67_RS21395	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H0S67_RS21415	ENOG4105CI0	Citrate lyase
H0S67_RS21420	ENOG4105CI0	Citrate lyase
H0S67_RS21430	ENOG4105D0M	Protease HtpX homolog
H0S67_RS21445	ENOG4105CGP	Urocanate hydratase
H0S67_RS21450	ENOG4105C84	Histidine ammonia-lyase
H0S67_RS21460	ENOG4105E5T	Major Facilitator Superfamily
H0S67_RS21485	ENOG4105DF6	Fe-S oxidoreductase
H0S67_RS21515	ENOG4105DHP	deoxycytidine triphosphate deaminase
H0S67_RS21520	ENOG41090WU	lipolytic protein G-D-S-L family
H0S67_RS21560	ENOG410635A	Membrane
H0S67_RS21595	ENOG4108W6C	Dehydrogenase
H0S67_RS21605	ENOG4105E39	Enoyl-CoA hydratase
H0S67_RS21630	ENOG4106IBR	Cupin domain
H0S67_RS21640	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
H0S67_RS21670	ENOG4105CHP	RNA polymerase
H0S67_RS21755	ENOG4105FDP	GntR family transcriptional regulator
H0S67_RS21770	ENOG4105C5Y	PTS System
H0S67_RS21810	ENOG4105F27	Major Facilitator
H0S67_RS21815	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
H0S67_RS21825	ENOG4105CD3	dihydroorotase
H0S67_RS21840	ENOG4107QPV	Serine Threonine protein kinase
H0S67_RS21845	ENOG4105CJ1	ABC, transporter
H0S67_RS21855	ENOG4105EMN	RNA polymerase sigma factor
H0S67_RS21875	ENOG4108RCM	Nitroreductase
H0S67_RS21885	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
H0S67_RS21890	ENOG4105CPP	Dehydrogenase, E1 component
H0S67_RS21975	ENOG41082T9	Membrane
H0S67_RS22010	ENOG4108JYK	Dehydrogenase
H0S67_RS22015	ENOG4105CPP	Dehydrogenase, E1 component
H0S67_RS22030	ENOG4108YIQ	Alpha beta hydrolase
H0S67_RS22105	ENOG4105NAF	rna polymerase sigma factor
H0S67_RS22130	ENOG4105K6V	RNA polymerase
H0S67_RS22145	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
H0S67_RS22160	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
H0S67_RS22165	ENOG4105M2Z	protein tyrosine serine phosphatase
H0S67_RS22185	ENOG4107QX3	carboxylase
H0S67_RS22205	ENOG4108RF4	Tetr family transcriptional regulator
H0S67_RS22240	ENOG4105W8D	rdd domain containing protein
H0S67_RS22270	ENOG4105C1G	acyl-Coa dehydrogenase
H0S67_RS22285	ENOG4105CHU	acetyl-coa acetyltransferase
H0S67_RS22295	ENOG4105FBA	Phospholipase Carboxylesterase
H0S67_RS22305	ENOG4105CGD	Nad-dependent epimerase dehydratase
H0S67_RS22350	ENOG4105CDA	abc transporter atp-binding protein
H0S67_RS22355	ENOG4105EAD	ABC transporter
H0S67_RS22375	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H0S67_RS22380	ENOG4105C87	Aminotransferase class I and II
H0S67_RS22425	ENOG4108KQI	regulatory protein luxr
H0S67_RS22455	ENOG4108TCJ	secreted hydrolase
H0S67_RS22465	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
H0S67_RS22475	ENOG4105C1G	acyl-Coa dehydrogenase
H0S67_RS22480	ENOG4108YYC	ycei family
H0S67_RS22485	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
H0S67_RS22530	ENOG4105DGW	oligopeptidase A
H0S67_RS22605	ENOG410905P	Pyridoxamine 5-phosphate
H0S67_RS22640	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
H0S67_RS22645	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
H0S67_RS22710	ENOG4105CDU	Replicative dna helicase
H0S67_RS22725	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
H0S67_RS22730	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
H0S67_RS22735	ENOG4107YH6	single-stranded DNA-binding protein
H0S67_RS22740	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
H0S67_RS22795	ENOG4105BZ4	penicillin-binding protein
H0S67_RS22820	ENOG4105CPC	Aldo Keto reductase
H0S67_RS22835	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
H0S67_RS22875	ENOG4105C3M	thioredoxin reductase
H0S67_RS22880	ENOG4105K63	Thioredoxin
H0S67_RS22890	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H0S67_RS22895	ENOG4105CPF	Cell wall formation (By similarity)
H0S67_RS22910	ENOG4107QJE	Chromosome Partitioning Protein
H0S67_RS22915	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
H0S67_RS22930	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
H0S67_RS22935	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
H0S67_RS22940	ENOG41084CH	50S ribosomal protein l34