locus-tag	class	description
BKM31_RS00015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS00045	COG0477	Major facilitator Superfamily
BKM31_RS00095	COG1643	Atp-dependent helicase
BKM31_RS00125	COG0405	Gamma-glutamyltransferase
BKM31_RS00130	COG0789	Transcriptional regulator
BKM31_RS00145	COG1132	(ABC) transporter
BKM31_RS00170	COG3903	Transcriptional regulator
BKM31_RS00170	COG3629	intracellular signal transduction
BKM31_RS00185	COG0673	inositol 2-dehydrogenase activity
BKM31_RS00200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKM31_RS00215	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKM31_RS00225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKM31_RS00260	COG3842	ATPase activity
BKM31_RS00320	COG0500	methyltransferase
BKM31_RS00335	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS00340	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS00385	COG2318	DinB family
BKM31_RS00415	COG2072	flavoprotein involved in K transport
BKM31_RS00420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKM31_RS00440	COG2226	methyltransferase
BKM31_RS00465	COG1881	PFAM PEBP family protein
BKM31_RS00500	COG0726	polysaccharide deacetylase
BKM31_RS00515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BKM31_RS00520	COG0823	Involved in the tonB-independent uptake of proteins
BKM31_RS00520	COG1506	peptidase
BKM31_RS00520	COG4946	Tricorn protease homolog
BKM31_RS00530	COG0745	RESPONSE REGULATOR receiver
BKM31_RS00535	COG2205	protein histidine kinase activity
BKM31_RS00570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS00575	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BKM31_RS00585	COG0525	valine-tRNA ligase activity
BKM31_RS00620	COG0756	dUTP diphosphatase activity
BKM31_RS00645	COG1695	Transcriptional regulator
BKM31_RS00655	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKM31_RS00690	COG1595	DNA-templated transcription, initiation
BKM31_RS00705	COG0596	Alpha beta hydrolase
BKM31_RS00720	COG0501	Belongs to the peptidase M48B family
BKM31_RS00740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKM31_RS00750	COG0531	amino acid
BKM31_RS00755	COG0569	domain protein
BKM31_RS00775	COG2133	pyrroloquinoline quinone binding
BKM31_RS00775	COG5183	chlorophyll binding
BKM31_RS00785	COG2340	Cysteine-rich secretory protein family
BKM31_RS00795	COG4977	sequence-specific DNA binding
BKM31_RS00810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKM31_RS00830	COG4585	Histidine kinase
BKM31_RS00835	COG4585	Histidine kinase
BKM31_RS00840	COG2197	response regulator
BKM31_RS00860	COG0601	transmembrane transport
BKM31_RS00870	COG0444	Belongs to the ABC transporter superfamily
BKM31_RS00905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKM31_RS00955	COG0477	Major facilitator Superfamily
BKM31_RS00990	COG4213	ABC transporter substrate-binding protein
BKM31_RS01000	COG4214	carbohydrate transport
BKM31_RS01010	COG2321	neutral zinc metallopeptidase
BKM31_RS01025	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BKM31_RS01035	COG0531	amino acid
BKM31_RS01045	COG1024	Enoyl-CoA hydratase
BKM31_RS01045	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKM31_RS01050	COG0183	Belongs to the thiolase family
BKM31_RS01070	COG1609	Transcriptional regulator
BKM31_RS01080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKM31_RS01095	COG0574	Belongs to the PEP-utilizing enzyme family
BKM31_RS01095	COG3848	Pyruvate phosphate dikinase
BKM31_RS01115	COG3850	Histidine kinase
BKM31_RS01120	COG2197	response regulator
BKM31_RS01135	COG0673	inositol 2-dehydrogenase activity
BKM31_RS01155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKM31_RS01165	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BKM31_RS01170	COG3253	May function as heme-dependent peroxidase
BKM31_RS01185	COG1131	(ABC) transporter
BKM31_RS01195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKM31_RS01210	COG4585	Histidine kinase
BKM31_RS01215	COG2197	response regulator
BKM31_RS01230	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS01250	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKM31_RS01260	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS01280	COG1793	dna ligase
BKM31_RS01305	COG1595	DNA-templated transcription, initiation
BKM31_RS01335	COG0175	sulfate reduction
BKM31_RS01345	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKM31_RS01355	COG3304	Inner membrane component domain
BKM31_RS01360	COG1295	ribonuclease BN
BKM31_RS01370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKM31_RS01390	COG1162	GTPase activity
BKM31_RS01445	COG0277	FAD linked oxidase domain protein
BKM31_RS01460	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKM31_RS01465	COG2814	Major facilitator Superfamily
BKM31_RS01485	COG0515	serine threonine protein kinase
BKM31_RS01485	COG2815	serine threonine protein kinase
BKM31_RS01510	COG2233	PERMEase
BKM31_RS01515	COG2233	PERMEase
BKM31_RS01555	COG1609	Transcriptional regulator
BKM31_RS01585	COG1294	oxidase, subunit
BKM31_RS01590	COG1271	oxidase subunit
BKM31_RS01595	COG0726	polysaccharide deacetylase
BKM31_RS01620	COG1435	thymidine kinase activity
BKM31_RS01715	COG0667	Aldo Keto reductase
BKM31_RS01725	COG4129	membrane
BKM31_RS01745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKM31_RS01760	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKM31_RS01765	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKM31_RS01770	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKM31_RS01775	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKM31_RS01815	COG1022	Amp-dependent synthetase and ligase
BKM31_RS01875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKM31_RS01880	COG2367	Beta-lactamase
BKM31_RS01885	COG0596	Alpha beta hydrolase
BKM31_RS01915	COG1132	(ABC) transporter
BKM31_RS01920	COG1132	(ABC) transporter
BKM31_RS01955	COG0386	Belongs to the glutathione peroxidase family
BKM31_RS01985	COG0300	oxidoreductase activity
BKM31_RS02005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKM31_RS02015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS02030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKM31_RS02040	COG4221	oxidoreductase activity
BKM31_RS02060	COG0714	Associated with various cellular activities
BKM31_RS02070	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BKM31_RS02075	COG0477	Major facilitator Superfamily
BKM31_RS02090	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS02115	COG1024	Enoyl-CoA hydratase
BKM31_RS02135	COG0419	ATPase involved in DNA repair
BKM31_RS02135	COG0419	ATPase involved in DNA repair
BKM31_RS02145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKM31_RS02150	COG0477	Major facilitator Superfamily
BKM31_RS02155	COG1252	NADH dehydrogenase
BKM31_RS02165	COG0372	Belongs to the citrate synthase family
BKM31_RS02200	COG0714	Associated with various cellular activities
BKM31_RS02245	COG0598	Magnesium transport protein CorA
BKM31_RS02290	COG1131	(ABC) transporter
BKM31_RS02295	COG1695	Transcriptional regulator
BKM31_RS02305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKM31_RS02320	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS02330	COG1672	PFAM Archaeal ATPase
BKM31_RS02330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKM31_RS02355	COG2313	pseudouridylate synthase activity
BKM31_RS02360	COG2855	membrane
BKM31_RS02385	COG0745	RESPONSE REGULATOR receiver
BKM31_RS02390	COG2205	protein histidine kinase activity
BKM31_RS02400	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKM31_RS02410	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS02415	COG1879	ABC-type sugar transport system periplasmic component
BKM31_RS02470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKM31_RS02480	COG0277	FAD linked oxidase domain protein
BKM31_RS02490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS02495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKM31_RS02515	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BKM31_RS02530	COG1597	lipid kinase activity
BKM31_RS02535	COG4279	zinc finger
BKM31_RS02540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKM31_RS02560	COG1295	ribonuclease BN
BKM31_RS02560	COG1959	2 iron, 2 sulfur cluster binding
BKM31_RS02590	COG3275	phosphorelay sensor kinase activity
BKM31_RS02595	COG3279	Response regulator of the LytR AlgR family
BKM31_RS02605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKM31_RS02625	COG1609	Transcriptional regulator
BKM31_RS02630	COG0626	cystathionine gamma-synthase activity
BKM31_RS02645	COG0395	ABC-type sugar transport system, permease component
BKM31_RS02655	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKM31_RS02665	COG1175	transmembrane transport
BKM31_RS02670	COG0395	ABC-type sugar transport system, permease component
BKM31_RS02695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKM31_RS02705	COG1940	carbohydrate kinase activity
BKM31_RS02710	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BKM31_RS02740	COG0789	Transcriptional regulator
BKM31_RS02790	COG2124	cytochrome p450
BKM31_RS02805	COG0667	Aldo Keto reductase
BKM31_RS02810	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS02865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BKM31_RS02865	COG1796	DNA polymerase
BKM31_RS02870	COG0667	Aldo Keto reductase
BKM31_RS02875	COG4585	Histidine kinase
BKM31_RS02880	COG0515	serine threonine protein kinase
BKM31_RS02885	COG1132	(ABC) transporter
BKM31_RS02890	COG1132	(ABC) transporter
BKM31_RS02895	COG1505	serine-type exopeptidase activity
BKM31_RS02900	COG2197	response regulator
BKM31_RS02920	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS02940	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS02955	COG1793	dna ligase
BKM31_RS02955	COG3285	dna ligase
BKM31_RS02960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS02970	COG0028	Belongs to the TPP enzyme family
BKM31_RS02975	COG1414	Transcriptional regulator
BKM31_RS03035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKM31_RS03040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKM31_RS03050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKM31_RS03050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKM31_RS03055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKM31_RS03100	COG2124	cytochrome p450
BKM31_RS03130	COG0667	Aldo Keto reductase
BKM31_RS03135	COG2197	response regulator
BKM31_RS03140	COG4585	Histidine kinase
BKM31_RS03175	COG3618	amidohydrolase
BKM31_RS03195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKM31_RS03230	COG2340	Cysteine-rich secretory protein family
BKM31_RS03250	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS03265	COG1764	response to oxidative stress
BKM31_RS03305	COG1053	succinate dehydrogenase
BKM31_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS03345	COG2197	response regulator
BKM31_RS03355	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKM31_RS03355	COG1672	PFAM Archaeal ATPase
BKM31_RS03360	COG1672	PFAM Archaeal ATPase
BKM31_RS03360	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKM31_RS03365	COG2813	Specifically methylates the guanine in position
BKM31_RS03385	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKM31_RS03405	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BKM31_RS03450	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKM31_RS03460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS03465	COG3485	protocatechuate 3,4-dioxygenase
BKM31_RS03470	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS03510	COG0137	argininosuccinate synthase activity
BKM31_RS03550	COG4585	Histidine kinase
BKM31_RS03555	COG2197	response regulator
BKM31_RS03565	COG2226	methyltransferase
BKM31_RS03580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKM31_RS03580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKM31_RS03625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS03630	COG1404	Belongs to the peptidase S8 family
BKM31_RS03640	COG3387	PFAM Glycoside hydrolase 15-related
BKM31_RS03650	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS03660	COG2271	Major facilitator Superfamily
BKM31_RS03675	COG4326	sporulation control protein
BKM31_RS03720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BKM31_RS03725	COG0297	glycogen (starch) synthase activity
BKM31_RS03760	COG0395	ABC-type sugar transport system, permease component
BKM31_RS03765	COG3459	Glycosyltransferase 36 associated
BKM31_RS03865	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS03885	COG0395	ABC-type sugar transport system, permease component
BKM31_RS03890	COG1175	transmembrane transport
BKM31_RS03940	COG2207	Transcriptional regulator
BKM31_RS03950	COG3345	alpha-galactosidase
BKM31_RS03955	COG1175	transmembrane transport
BKM31_RS03960	COG0395	ABC-type sugar transport system, permease component
BKM31_RS03965	COG1653	transport
BKM31_RS03970	COG3540	Alkaline phosphatase
BKM31_RS03980	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BKM31_RS04010	COG4585	Histidine kinase
BKM31_RS04015	COG2197	response regulator
BKM31_RS04030	COG0738	Major facilitator superfamily
BKM31_RS04040	COG1175	transmembrane transport
BKM31_RS04075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKM31_RS04090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKM31_RS04100	COG0284	orotidine-5'-phosphate decarboxylase activity
BKM31_RS04115	COG0561	phosphatase activity
BKM31_RS04135	COG1733	regulation of RNA biosynthetic process
BKM31_RS04145	COG1515	deoxyribonuclease V activity
BKM31_RS04155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS04160	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS04165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKM31_RS04165	COG0519	Catalyzes the synthesis of GMP from XMP
BKM31_RS04170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKM31_RS04215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS04250	COG0772	Belongs to the SEDS family
BKM31_RS04255	COG0768	penicillin binding
BKM31_RS04305	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS04320	COG0640	Transcriptional regulator
BKM31_RS04325	COG2986	histidine ammonia-lyase
BKM31_RS04340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKM31_RS04340	COG0512	Glutamine amidotransferase of anthranilate synthase
BKM31_RS04380	COG0745	RESPONSE REGULATOR receiver
BKM31_RS04405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKM31_RS04410	COG2205	protein histidine kinase activity
BKM31_RS04415	COG0745	RESPONSE REGULATOR receiver
BKM31_RS04420	COG0475	glutathione-regulated potassium exporter activity
BKM31_RS04430	COG0492	ferredoxin-NADP+ reductase activity
BKM31_RS04435	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS04470	COG3387	PFAM Glycoside hydrolase 15-related
BKM31_RS04475	COG1672	PFAM Archaeal ATPase
BKM31_RS04475	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKM31_RS04485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKM31_RS04510	COG0395	ABC-type sugar transport system, permease component
BKM31_RS04515	COG1175	transmembrane transport
BKM31_RS04520	COG2182	Extracellular solute-binding protein
BKM31_RS04525	COG1940	carbohydrate kinase activity
BKM31_RS04550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKM31_RS04555	COG2124	cytochrome p450
BKM31_RS04605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKM31_RS04610	COG2314	TM2 domain
BKM31_RS04645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS04655	COG1649	PFAM Uncharacterised BCR, COG1649
BKM31_RS04670	COG1560	Kdo2-lipid A biosynthetic process
BKM31_RS04675	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS04690	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BKM31_RS04695	COG3540	Alkaline phosphatase
BKM31_RS04705	COG2814	Major facilitator Superfamily
BKM31_RS04715	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BKM31_RS04720	COG0217	transcriptional regulatory protein
BKM31_RS04725	COG1175	transmembrane transport
BKM31_RS04735	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BKM31_RS04745	COG0632	four-way junction helicase activity
BKM31_RS04750	COG2255	four-way junction helicase activity
BKM31_RS04755	COG1862	Preprotein translocase
BKM31_RS04760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKM31_RS04765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKM31_RS04770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKM31_RS04775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKM31_RS04785	COG1196	nuclear chromosome segregation
BKM31_RS04790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKM31_RS04800	COG0124	histidyl-tRNA synthetase
BKM31_RS04805	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKM31_RS04810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKM31_RS04845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKM31_RS04850	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BKM31_RS04855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKM31_RS04860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKM31_RS04865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKM31_RS04880	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKM31_RS04885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKM31_RS04890	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKM31_RS04895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKM31_RS04900	COG5002	protein histidine kinase activity
BKM31_RS04905	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKM31_RS04910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKM31_RS04910	COG0072	phenylalanine-tRNA ligase activity
BKM31_RS04945	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS04960	COG3833	ABC-type maltose transport systems, permease component
BKM31_RS04965	COG1175	transmembrane transport
BKM31_RS04970	COG1653	transport
BKM31_RS05015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKM31_RS05020	COG0596	Alpha beta hydrolase
BKM31_RS05025	COG1404	Belongs to the peptidase S8 family
BKM31_RS05045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS05050	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BKM31_RS05055	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BKM31_RS05060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS05065	COG0601	transmembrane transport
BKM31_RS05070	COG0747	negative chemotaxis
BKM31_RS05075	COG1737	Transcriptional regulator
BKM31_RS05085	COG3119	arylsulfatase activity
BKM31_RS05085	COG3408	Glycogen debranching enzyme
BKM31_RS05105	COG0437	4 iron, 4 sulfur cluster binding
BKM31_RS05110	COG3383	formate dehydrogenase (NAD+) activity
BKM31_RS05110	COG0243	molybdopterin cofactor binding
BKM31_RS05115	COG1070	Carbohydrate kinase
BKM31_RS05125	COG0673	inositol 2-dehydrogenase activity
BKM31_RS05135	COG3254	rhamnose metabolic process
BKM31_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS05145	COG3347	Dehydrogenase
BKM31_RS05155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BKM31_RS05160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BKM31_RS05165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKM31_RS05170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKM31_RS05175	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKM31_RS05180	COG1438	arginine binding
BKM31_RS05185	COG0137	argininosuccinate synthase activity
BKM31_RS05190	COG0165	Argininosuccinate lyase
BKM31_RS05195	COG2094	Belongs to the DNA glycosylase MPG family
BKM31_RS05205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKM31_RS05245	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BKM31_RS05275	COG0789	Transcriptional regulator
BKM31_RS05280	COG0647	UMP catabolic process
BKM31_RS05300	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKM31_RS05305	COG0497	DNA recombination
BKM31_RS05330	COG0297	glycogen (starch) synthase activity
BKM31_RS05340	COG0688	phosphatidylethanolamine metabolic process
BKM31_RS05355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKM31_RS05365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKM31_RS05390	COG0322	excinuclease ABC activity
BKM31_RS05395	COG1660	Displays ATPase and GTPase activities
BKM31_RS05400	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BKM31_RS05405	COG1481	regulation of sporulation
BKM31_RS05415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKM31_RS05420	COG0126	phosphoglycerate kinase activity
BKM31_RS05425	COG0149	triose-phosphate isomerase activity
BKM31_RS05430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKM31_RS05440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKM31_RS05445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS05455	COG0542	response to heat
BKM31_RS05485	COG4221	oxidoreductase activity
BKM31_RS05495	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKM31_RS05515	COG0363	glucosamine-6-phosphate deaminase activity
BKM31_RS05530	COG0166	Belongs to the GPI family
BKM31_RS05535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BKM31_RS05545	COG0109	protoheme IX farnesyltransferase activity
BKM31_RS05565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS05585	COG3938	Belongs to the proline racemase family
BKM31_RS05600	COG1802	Transcriptional regulator
BKM31_RS05610	COG2814	Major facilitator Superfamily
BKM31_RS05620	COG1131	(ABC) transporter
BKM31_RS05625	COG2814	Major facilitator Superfamily
BKM31_RS05645	COG2146	nitrite reductase [NAD(P)H] activity
BKM31_RS05650	COG0396	ATPase activity
BKM31_RS05655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKM31_RS05660	COG0822	iron-sulfur transferase activity
BKM31_RS05665	COG2151	metal-sulfur cluster biosynthetic enzyme
BKM31_RS05670	COG0513	Belongs to the DEAD box helicase family
BKM31_RS05675	COG0395	ABC-type sugar transport system, permease component
BKM31_RS05680	COG1175	transmembrane transport
BKM31_RS05685	COG2182	Extracellular solute-binding protein
BKM31_RS05690	COG3458	cephalosporin-C deacetylase activity
BKM31_RS05695	COG0140	phosphoribosyl-ATP diphosphatase activity
BKM31_RS05700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BKM31_RS05710	COG1131	(ABC) transporter
BKM31_RS05720	COG4585	Histidine kinase
BKM31_RS05725	COG2197	response regulator
BKM31_RS05770	COG0702	epimerase
BKM31_RS05790	COG5578	integral membrane protein
BKM31_RS05795	COG1653	transport
BKM31_RS05800	COG4209	transmembrane transport
BKM31_RS05805	COG0395	ABC-type sugar transport system, permease component
BKM31_RS05820	COG0488	(ABC) transporter
BKM31_RS05830	COG1024	Enoyl-CoA hydratase
BKM31_RS05835	COG1132	(ABC) transporter
BKM31_RS05845	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKM31_RS05850	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKM31_RS05865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKM31_RS05880	COG0584	glycerophosphoryl diester phosphodiesterase
BKM31_RS05885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKM31_RS05915	COG1132	(ABC) transporter
BKM31_RS05920	COG1132	(ABC) transporter
BKM31_RS05925	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKM31_RS05930	COG3012	SEC-C Motif Domain Protein
BKM31_RS05945	COG0395	ABC-type sugar transport system, permease component
BKM31_RS05950	COG1175	transmembrane transport
BKM31_RS05970	COG1959	2 iron, 2 sulfur cluster binding
BKM31_RS05975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKM31_RS05975	COG1017	nitric oxide dioxygenase activity
BKM31_RS05995	COG1501	Belongs to the glycosyl hydrolase 31 family
BKM31_RS06030	COG3507	Belongs to the glycosyl hydrolase 43 family
BKM31_RS06080	COG3387	PFAM Glycoside hydrolase 15-related
BKM31_RS06085	COG2364	Membrane
BKM31_RS06095	COG2860	membrane
BKM31_RS06100	COG3104	oligopeptide transport
BKM31_RS06125	COG2910	NAD(P)H-binding
BKM31_RS06130	COG1733	regulation of RNA biosynthetic process
BKM31_RS06135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKM31_RS06150	COG3360	Dodecin
BKM31_RS06180	COG3547	Transposase (IS116 IS110 IS902 family)
BKM31_RS06200	COG0667	Aldo Keto reductase
BKM31_RS06225	COG0215	cysteine-tRNA ligase activity
BKM31_RS06230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKM31_RS06235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM31_RS06245	COG0300	oxidoreductase activity
BKM31_RS06250	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BKM31_RS06250	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKM31_RS06255	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BKM31_RS06260	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS06275	COG2192	nodulation
BKM31_RS06280	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BKM31_RS06300	COG2319	Wd-40 repeat
BKM31_RS06300	COG4249	Peptidase C14 caspase catalytic subunit p20
BKM31_RS06305	COG0242	peptide deformylase activity
BKM31_RS06340	COG0646	methionine synthase
BKM31_RS06340	COG1410	methionine synthase
BKM31_RS06345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKM31_RS06355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS06360	COG0747	negative chemotaxis
BKM31_RS06370	COG0444	Belongs to the ABC transporter superfamily
BKM31_RS06375	COG4608	Belongs to the ABC transporter superfamily
BKM31_RS06380	COG2197	response regulator
BKM31_RS06395	COG1994	Peptidase M50
BKM31_RS06395	COG0517	IMP dehydrogenase activity
BKM31_RS06415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKM31_RS06425	COG1222	aaa ATPase
BKM31_RS06430	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BKM31_RS06445	COG4122	O-methyltransferase activity
BKM31_RS06470	COG3842	ATPase activity
BKM31_RS06475	COG0395	ABC-type sugar transport system, permease component
BKM31_RS06480	COG1175	transmembrane transport
BKM31_RS06490	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BKM31_RS06495	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BKM31_RS06505	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BKM31_RS06510	COG0545	Peptidyl-prolyl cis-trans isomerase
BKM31_RS06550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKM31_RS06555	COG0805	protein transport
BKM31_RS06575	COG1132	(ABC) transporter
BKM31_RS06580	COG1309	transcriptional regulator
BKM31_RS06655	COG0006	proline dipeptidase activity
BKM31_RS06665	COG4172	Belongs to the ABC transporter superfamily
BKM31_RS06680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS06685	COG0747	negative chemotaxis
BKM31_RS06710	COG2188	Transcriptional regulator
BKM31_RS06730	COG1802	Transcriptional regulator
BKM31_RS06735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKM31_RS06780	COG3537	Alpha-1,2-mannosidase
BKM31_RS06805	COG3639	organic phosphonate transmembrane transporter activity
BKM31_RS06810	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKM31_RS06815	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BKM31_RS06845	COG0765	amino acid transport
BKM31_RS06855	COG2843	Capsule synthesis protein
BKM31_RS06885	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS06900	COG2070	2-Nitropropane dioxygenase
BKM31_RS06920	COG2197	response regulator
BKM31_RS06925	COG2732	(Barnase) inhibitor
BKM31_RS06970	COG0681	Belongs to the peptidase S26 family
BKM31_RS07000	COG0242	peptide deformylase activity
BKM31_RS07010	COG1131	(ABC) transporter
BKM31_RS07060	COG2197	response regulator
BKM31_RS07065	COG3321	synthase
BKM31_RS07065	COG0604	alcohol dehydrogenase
BKM31_RS07105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS07110	COG4106	trans-aconitate 2-methyltransferase activity
BKM31_RS07115	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKM31_RS07130	COG0702	epimerase
BKM31_RS07145	COG0657	acetylesterase activity
BKM31_RS07155	COG2197	response regulator
BKM31_RS07160	COG4585	Histidine kinase
BKM31_RS07170	COG1131	(ABC) transporter
BKM31_RS07195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKM31_RS07200	COG1082	Xylose isomerase domain protein TIM barrel
BKM31_RS07200	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BKM31_RS07205	COG0477	Major facilitator Superfamily
BKM31_RS07225	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS07235	COG0028	Belongs to the TPP enzyme family
BKM31_RS07240	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS07245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKM31_RS07320	COG1797	cobyrinic acid a,c-diamide synthase activity
BKM31_RS07325	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BKM31_RS07390	COG4585	Histidine kinase
BKM31_RS07395	COG0598	Magnesium transport protein CorA
BKM31_RS07400	COG0477	Major facilitator Superfamily
BKM31_RS07440	COG1595	DNA-templated transcription, initiation
BKM31_RS07470	COG2226	methyltransferase
BKM31_RS07480	COG1414	Transcriptional regulator
BKM31_RS07485	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS07495	COG1309	transcriptional regulator
BKM31_RS07500	COG0596	Alpha beta hydrolase
BKM31_RS07505	COG0747	negative chemotaxis
BKM31_RS07510	COG0601	transmembrane transport
BKM31_RS07515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS07525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS07565	COG1609	Transcriptional regulator
BKM31_RS07575	COG0673	inositol 2-dehydrogenase activity
BKM31_RS07585	COG2186	Transcriptional regulator
BKM31_RS07590	COG0579	oxidoreductase
BKM31_RS07615	COG1120	ATPase activity
BKM31_RS07620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKM31_RS07630	COG0085	RNA polymerase activity
BKM31_RS07635	COG0515	serine threonine protein kinase
BKM31_RS07635	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS07645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS07650	COG4977	sequence-specific DNA binding
BKM31_RS07655	COG3629	intracellular signal transduction
BKM31_RS07680	COG3540	Alkaline phosphatase
BKM31_RS07685	COG1349	DNA-binding transcription factor activity
BKM31_RS07690	COG1653	transport
BKM31_RS07695	COG1175	transmembrane transport
BKM31_RS07700	COG0395	ABC-type sugar transport system, permease component
BKM31_RS07715	COG2208	phosphoserine phosphatase activity
BKM31_RS07715	COG2770	Histidine kinase
BKM31_RS07730	COG3537	Alpha-1,2-mannosidase
BKM31_RS07760	COG1024	Enoyl-CoA hydratase
BKM31_RS07770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKM31_RS07775	COG2151	metal-sulfur cluster biosynthetic enzyme
BKM31_RS07780	COG3396	Phenylacetate-CoA oxygenase
BKM31_RS07785	COG3460	Phenylacetate-CoA oxygenase
BKM31_RS07790	COG3396	Phenylacetate-CoA oxygenase
BKM31_RS07795	COG2030	dehydratase
BKM31_RS07795	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS07815	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS07830	COG4608	Belongs to the ABC transporter superfamily
BKM31_RS07835	COG0444	Belongs to the ABC transporter superfamily
BKM31_RS07895	COG0181	hydroxymethylbilane synthase activity
BKM31_RS07935	COG1024	Enoyl-CoA hydratase
BKM31_RS07940	COG2197	response regulator
BKM31_RS07960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS07960	COG0515	serine threonine protein kinase
BKM31_RS07970	COG1802	Transcriptional regulator
BKM31_RS07975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS07995	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKM31_RS08025	COG0745	RESPONSE REGULATOR receiver
BKM31_RS08030	COG2205	protein histidine kinase activity
BKM31_RS08035	COG0477	Major facilitator Superfamily
BKM31_RS08050	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS08070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS08075	COG4591	ABC-type transport system involved in lipoprotein release permease component
BKM31_RS08075	COG1136	(ABC) transporter
BKM31_RS08080	COG1136	(ABC) transporter
BKM31_RS08090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKM31_RS08095	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BKM31_RS08130	COG1595	DNA-templated transcription, initiation
BKM31_RS08140	COG2271	Major facilitator Superfamily
BKM31_RS08170	COG0583	DNA-binding transcription factor activity
BKM31_RS08175	COG2814	Major facilitator Superfamily
BKM31_RS08185	COG0583	DNA-binding transcription factor activity
BKM31_RS08255	COG0702	epimerase
BKM31_RS08275	COG1309	transcriptional regulator
BKM31_RS08300	COG0772	Belongs to the SEDS family
BKM31_RS08305	COG0768	penicillin binding
BKM31_RS08315	COG1792	Involved in formation and maintenance of cell shape
BKM31_RS08325	COG0746	molybdenum cofactor guanylyltransferase activity
BKM31_RS08340	COG0640	Transcriptional regulator
BKM31_RS08375	COG4149	molybdate abc transporter
BKM31_RS08380	COG1175	transmembrane transport
BKM31_RS08385	COG1653	transport
BKM31_RS08390	COG1609	Transcriptional regulator
BKM31_RS08415	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS08440	COG3629	intracellular signal transduction
BKM31_RS08440	COG3903	Transcriptional regulator
BKM31_RS08455	COG1940	carbohydrate kinase activity
BKM31_RS08455	COG1846	Transcriptional regulator
BKM31_RS08465	COG0596	Alpha beta hydrolase
BKM31_RS08470	COG4977	sequence-specific DNA binding
BKM31_RS08480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKM31_RS08490	COG0300	oxidoreductase activity
BKM31_RS08515	COG2271	Major facilitator Superfamily
BKM31_RS08535	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BKM31_RS08545	COG0436	Aminotransferase
BKM31_RS08580	COG1739	Uncharacterized protein family UPF0029
BKM31_RS08585	COG1169	isochorismate synthase
BKM31_RS08625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKM31_RS08630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKM31_RS08635	COG4106	trans-aconitate 2-methyltransferase activity
BKM31_RS08640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKM31_RS08645	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS08650	COG0793	Belongs to the peptidase S41A family
BKM31_RS08650	COG4946	Tricorn protease homolog
BKM31_RS08670	COG1595	DNA-templated transcription, initiation
BKM31_RS08705	COG1309	transcriptional regulator
BKM31_RS08710	COG3631	Ketosteroid isomerase-related protein
BKM31_RS08715	COG0702	epimerase
BKM31_RS08730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKM31_RS08745	COG2205	protein histidine kinase activity
BKM31_RS08750	COG0745	RESPONSE REGULATOR receiver
BKM31_RS08770	COG0577	efflux transmembrane transporter activity
BKM31_RS08770	COG1136	(ABC) transporter
BKM31_RS08780	COG3973	AAA domain
BKM31_RS08790	COG0659	secondary active sulfate transmembrane transporter activity
BKM31_RS08855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKM31_RS08870	COG1309	transcriptional regulator
BKM31_RS08890	COG0439	Biotin carboxylase
BKM31_RS08960	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS08965	COG1609	Transcriptional regulator
BKM31_RS08975	COG2271	Major facilitator Superfamily
BKM31_RS08980	COG1802	Transcriptional regulator
BKM31_RS08990	COG2205	protein histidine kinase activity
BKM31_RS08995	COG2205	protein histidine kinase activity
BKM31_RS09035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKM31_RS09045	COG1653	transport
BKM31_RS09050	COG1175	transmembrane transport
BKM31_RS09055	COG0395	ABC-type sugar transport system, permease component
BKM31_RS09060	COG1082	Xylose isomerase domain protein TIM barrel
BKM31_RS09095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKM31_RS09105	COG2267	carboxylic ester hydrolase activity
BKM31_RS09125	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS09130	COG1609	Transcriptional regulator
BKM31_RS09135	COG2197	response regulator
BKM31_RS09140	COG4585	Histidine kinase
BKM31_RS09165	COG0778	Nitroreductase
BKM31_RS09175	COG1846	Transcriptional regulator
BKM31_RS09185	COG2249	NAD(P)H dehydrogenase (quinone) activity
BKM31_RS09190	COG3401	FG-GAP repeat protein
BKM31_RS09195	COG1349	DNA-binding transcription factor activity
BKM31_RS09205	COG3684	Belongs to the aldolase LacD family
BKM31_RS09255	COG1414	Transcriptional regulator
BKM31_RS09315	COG2239	Acts as a magnesium transporter
BKM31_RS09350	COG1121	(ABC) transporter
BKM31_RS09410	COG1104	cysteine desulfurase activity
BKM31_RS09415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS09430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKM31_RS09440	COG0667	Aldo Keto reductase
BKM31_RS09450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKM31_RS09470	COG3629	intracellular signal transduction
BKM31_RS09470	COG3903	Transcriptional regulator
BKM31_RS09475	COG1505	serine-type exopeptidase activity
BKM31_RS09480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKM31_RS09485	COG2814	Major facilitator Superfamily
BKM31_RS09490	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BKM31_RS09500	COG0277	FAD linked oxidase domain protein
BKM31_RS09525	COG4941	Belongs to the sigma-70 factor family
BKM31_RS09535	COG1119	ATPase activity
BKM31_RS09585	COG0596	Alpha beta hydrolase
BKM31_RS09655	COG0659	secondary active sulfate transmembrane transporter activity
BKM31_RS09665	COG1132	(ABC) transporter
BKM31_RS09675	COG1073	alpha beta
BKM31_RS09690	COG0501	Belongs to the peptidase M48B family
BKM31_RS09710	COG1832	CoA-binding protein
BKM31_RS09775	COG3751	2OG-Fe(II) oxygenase superfamily
BKM31_RS09860	COG0667	Aldo Keto reductase
BKM31_RS09875	COG2319	Wd-40 repeat
BKM31_RS09875	COG4249	Peptidase C14 caspase catalytic subunit p20
BKM31_RS09885	COG1216	Glycosyl transferase, family 2
BKM31_RS09890	COG1216	Glycosyl transferase, family 2
BKM31_RS09900	COG1215	transferase activity, transferring glycosyl groups
BKM31_RS09905	COG1215	transferase activity, transferring glycosyl groups
BKM31_RS09925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM31_RS09930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKM31_RS09935	COG3903	Transcriptional regulator
BKM31_RS09935	COG3629	intracellular signal transduction
BKM31_RS09945	COG2201	protein-glutamate methylesterase activity
BKM31_RS09960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS09965	COG3559	Exporter of polyketide antibiotics
BKM31_RS09970	COG1131	(ABC) transporter
BKM31_RS09975	COG0300	oxidoreductase activity
BKM31_RS09990	COG3226	Transcriptional regulator
BKM31_RS10010	COG0601	transmembrane transport
BKM31_RS10015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS10020	COG0444	Belongs to the ABC transporter superfamily
BKM31_RS10025	COG4608	Belongs to the ABC transporter superfamily
BKM31_RS10035	COG0395	ABC-type sugar transport system, permease component
BKM31_RS10040	COG1175	transmembrane transport
BKM31_RS10055	COG1609	Transcriptional regulator
BKM31_RS10060	COG2188	Transcriptional regulator
BKM31_RS10065	COG0363	glucosamine-6-phosphate deaminase activity
BKM31_RS10070	COG4941	Belongs to the sigma-70 factor family
BKM31_RS10095	COG1357	PFAM Pentapeptide repeats (8 copies)
BKM31_RS10100	COG1846	Transcriptional regulator
BKM31_RS10105	COG0697	spore germination
BKM31_RS10115	COG0590	tRNA wobble adenosine to inosine editing
BKM31_RS10130	COG2197	response regulator
BKM31_RS10155	COG2197	response regulator
BKM31_RS10165	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS10170	COG4221	oxidoreductase activity
BKM31_RS10180	COG3384	dioxygenase
BKM31_RS10185	COG1063	alcohol dehydrogenase
BKM31_RS10190	COG0129	dihydroxy-acid dehydratase activity
BKM31_RS10195	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS10215	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS10245	COG2205	protein histidine kinase activity
BKM31_RS10250	COG1733	regulation of RNA biosynthetic process
BKM31_RS10255	COG2197	response regulator
BKM31_RS10260	COG4585	Histidine kinase
BKM31_RS10270	COG1131	(ABC) transporter
BKM31_RS10275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKM31_RS10295	COG1253	flavin adenine dinucleotide binding
BKM31_RS10305	COG2175	clavaminate synthase activity
BKM31_RS10310	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BKM31_RS10320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKM31_RS10330	COG1832	CoA-binding protein
BKM31_RS10340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKM31_RS10365	COG1846	Transcriptional regulator
BKM31_RS10370	COG0702	epimerase
BKM31_RS10380	COG2890	protein-(glutamine-N5) methyltransferase activity
BKM31_RS10400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKM31_RS10430	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS10440	COG0367	asparagine synthase
BKM31_RS10445	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKM31_RS10445	COG2308	Evidence 4 Homologs of previously reported genes of
BKM31_RS10450	COG5592	hemerythrin HHE cation binding domain
BKM31_RS10465	COG2124	cytochrome p450
BKM31_RS10470	COG5520	Belongs to the glycosyl hydrolase 30 family
BKM31_RS10475	COG1609	Transcriptional regulator
BKM31_RS10495	COG0673	inositol 2-dehydrogenase activity
BKM31_RS10500	COG1609	Transcriptional regulator
BKM31_RS10505	COG3693	PFAM glycoside hydrolase, family 10
BKM31_RS10520	COG5520	Belongs to the glycosyl hydrolase 30 family
BKM31_RS10540	COG2076	Multidrug Resistance protein
BKM31_RS10555	COG1376	ErfK ybiS ycfS ynhG family protein
BKM31_RS10580	COG3509	depolymerase
BKM31_RS10585	COG3507	Belongs to the glycosyl hydrolase 43 family
BKM31_RS10590	COG3345	alpha-galactosidase
BKM31_RS10600	COG0395	ABC-type sugar transport system, permease component
BKM31_RS10605	COG1175	transmembrane transport
BKM31_RS10620	COG1609	Transcriptional regulator
BKM31_RS10625	COG2382	esterase
BKM31_RS10625	COG3507	Belongs to the glycosyl hydrolase 43 family
BKM31_RS10625	COG3693	PFAM glycoside hydrolase, family 10
BKM31_RS10630	COG1653	transport
BKM31_RS10635	COG1175	transmembrane transport
BKM31_RS10640	COG0395	ABC-type sugar transport system, permease component
BKM31_RS10655	COG0673	inositol 2-dehydrogenase activity
BKM31_RS10675	COG3962	Belongs to the TPP enzyme family
BKM31_RS10710	COG0561	phosphatase activity
BKM31_RS10735	COG0783	Belongs to the Dps family
BKM31_RS10750	COG2267	carboxylic ester hydrolase activity
BKM31_RS10755	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS10760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKM31_RS10770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKM31_RS10775	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS10780	COG2755	lipolytic protein G-D-S-L family
BKM31_RS10780	COG0657	acetylesterase activity
BKM31_RS10800	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS10805	COG0531	amino acid
BKM31_RS10825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKM31_RS10835	COG1309	transcriptional regulator
BKM31_RS10840	COG1131	(ABC) transporter
BKM31_RS10860	COG2207	Transcriptional regulator
BKM31_RS10875	COG2080	2 iron, 2 sulfur cluster binding
BKM31_RS10880	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKM31_RS10885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKM31_RS10910	COG0667	Aldo Keto reductase
BKM31_RS10915	COG0137	argininosuccinate synthase activity
BKM31_RS10935	COG2267	carboxylic ester hydrolase activity
BKM31_RS10940	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS10945	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS10970	COG0175	sulfate reduction
BKM31_RS10985	COG1132	(ABC) transporter
BKM31_RS10995	COG1132	(ABC) transporter
BKM31_RS11000	COG2382	esterase
BKM31_RS11025	COG0583	DNA-binding transcription factor activity
BKM31_RS11050	COG2072	flavoprotein involved in K transport
BKM31_RS11060	COG2267	carboxylic ester hydrolase activity
BKM31_RS11070	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKM31_RS11125	COG2172	sigma factor antagonist activity
BKM31_RS11140	COG0739	heme binding
BKM31_RS11155	COG1595	DNA-templated transcription, initiation
BKM31_RS11210	COG0456	acetyltransferase
BKM31_RS11215	COG0765	amino acid transport
BKM31_RS11220	COG1126	abc transporter atp-binding protein
BKM31_RS11240	COG2124	cytochrome p450
BKM31_RS11265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKM31_RS11295	COG3467	pyridoxamine 5'-phosphate
BKM31_RS11335	COG4585	Histidine kinase
BKM31_RS11340	COG1802	Transcriptional regulator
BKM31_RS11370	COG0431	NADPH-dependent FMN reductase
BKM31_RS11380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKM31_RS11385	COG0435	Glutathione S-transferase
BKM31_RS11390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKM31_RS11395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKM31_RS11400	COG1116	anion transmembrane transporter activity
BKM31_RS11405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS11410	COG2313	pseudouridylate synthase activity
BKM31_RS11420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKM31_RS11485	COG1846	Transcriptional regulator
BKM31_RS11490	COG2197	response regulator
BKM31_RS11525	COG1733	regulation of RNA biosynthetic process
BKM31_RS11535	COG0574	Belongs to the PEP-utilizing enzyme family
BKM31_RS11535	COG3848	Pyruvate phosphate dikinase
BKM31_RS11570	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKM31_RS11590	COG0667	Aldo Keto reductase
BKM31_RS11615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKM31_RS11655	COG4585	Histidine kinase
BKM31_RS11660	COG2197	response regulator
BKM31_RS11705	COG4585	Histidine kinase
BKM31_RS11715	COG4585	Histidine kinase
BKM31_RS11740	COG2186	Transcriptional regulator
BKM31_RS11755	COG0395	ABC-type sugar transport system, permease component
BKM31_RS11760	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS11765	COG2186	Transcriptional regulator
BKM31_RS11805	COG1609	Transcriptional regulator
BKM31_RS11810	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS11815	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS11825	COG1879	ABC-type sugar transport system periplasmic component
BKM31_RS11830	COG1609	Transcriptional regulator
BKM31_RS11835	COG1609	Transcriptional regulator
BKM31_RS11850	COG0395	ABC-type sugar transport system, permease component
BKM31_RS11865	COG0596	Alpha beta hydrolase
BKM31_RS11870	COG1234	tRNA 3'-trailer cleavage
BKM31_RS11930	COG1595	DNA-templated transcription, initiation
BKM31_RS11935	COG0667	Aldo Keto reductase
BKM31_RS11955	COG1874	Beta-galactosidase
BKM31_RS12000	COG0583	DNA-binding transcription factor activity
BKM31_RS12005	COG0587	DNA-directed DNA polymerase activity
BKM31_RS12030	COG4249	Peptidase C14 caspase catalytic subunit p20
BKM31_RS12030	COG2319	Wd-40 repeat
BKM31_RS12055	COG1073	alpha beta
BKM31_RS12055	COG2226	methyltransferase
BKM31_RS12065	COG1846	Transcriptional regulator
BKM31_RS12075	COG2124	cytochrome p450
BKM31_RS12100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKM31_RS12120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS12145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS12160	COG0154	amidase activity
BKM31_RS12190	COG1309	transcriptional regulator
BKM31_RS12225	COG3903	Transcriptional regulator
BKM31_RS12225	COG3629	intracellular signal transduction
BKM31_RS12240	COG2079	MmgE PrpD family protein
BKM31_RS12260	COG1846	Transcriptional regulator
BKM31_RS12265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS12270	COG1611	Belongs to the LOG family
BKM31_RS12275	COG0823	Involved in the tonB-independent uptake of proteins
BKM31_RS12275	COG1506	peptidase
BKM31_RS12275	COG4946	Tricorn protease homolog
BKM31_RS12280	COG2124	cytochrome p450
BKM31_RS12285	COG4941	Belongs to the sigma-70 factor family
BKM31_RS12290	COG3795	YCII-related domain
BKM31_RS12325	COG0129	dihydroxy-acid dehydratase activity
BKM31_RS12350	COG0477	Major facilitator Superfamily
BKM31_RS12365	COG2814	Major facilitator Superfamily
BKM31_RS12385	COG1309	transcriptional regulator
BKM31_RS12390	COG1902	pentaerythritol trinitrate reductase activity
BKM31_RS12430	COG2890	protein-(glutamine-N5) methyltransferase activity
BKM31_RS12450	COG4585	Histidine kinase
BKM31_RS12485	COG2226	methyltransferase
BKM31_RS12485	COG1073	alpha beta
BKM31_RS12490	COG0789	Transcriptional regulator
BKM31_RS12495	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
BKM31_RS12535	COG2197	response regulator
BKM31_RS12540	COG4585	Histidine kinase
BKM31_RS12565	COG2807	transmembrane transport
BKM31_RS12570	COG1309	transcriptional regulator
BKM31_RS12585	COG1073	alpha beta
BKM31_RS12605	COG4585	Histidine kinase
BKM31_RS12645	COG1309	transcriptional regulator
BKM31_RS12670	COG2124	cytochrome p450
BKM31_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS12705	COG0583	DNA-binding transcription factor activity
BKM31_RS12715	COG2267	carboxylic ester hydrolase activity
BKM31_RS12725	COG0596	Alpha beta hydrolase
BKM31_RS12730	COG0673	inositol 2-dehydrogenase activity
BKM31_RS12750	COG1073	alpha beta
BKM31_RS12810	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKM31_RS12815	COG3795	YCII-related domain
BKM31_RS12855	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BKM31_RS12860	COG0583	DNA-binding transcription factor activity
BKM31_RS12920	COG3851	Histidine kinase
BKM31_RS12925	COG2197	response regulator
BKM31_RS12930	COG0009	L-threonylcarbamoyladenylate synthase
BKM31_RS12945	COG2205	protein histidine kinase activity
BKM31_RS12945	COG0784	Response regulator, receiver
BKM31_RS12950	COG0745	RESPONSE REGULATOR receiver
BKM31_RS12960	COG2814	Major facilitator Superfamily
BKM31_RS13015	COG4977	sequence-specific DNA binding
BKM31_RS13020	COG2814	Major facilitator Superfamily
BKM31_RS13050	COG2084	Dehydrogenase
BKM31_RS13055	COG0583	DNA-binding transcription factor activity
BKM31_RS13065	COG2267	carboxylic ester hydrolase activity
BKM31_RS13110	COG0702	epimerase
BKM31_RS13120	COG2226	methyltransferase
BKM31_RS13130	COG2375	cellular response to nickel ion
BKM31_RS13130	COG1132	(ABC) transporter
BKM31_RS13145	COG1376	ErfK ybiS ycfS ynhG family protein
BKM31_RS13150	COG0745	RESPONSE REGULATOR receiver
BKM31_RS13155	COG5002	protein histidine kinase activity
BKM31_RS13170	COG2197	response regulator
BKM31_RS13190	COG1595	DNA-templated transcription, initiation
BKM31_RS13195	COG3903	Transcriptional regulator
BKM31_RS13195	COG3629	intracellular signal transduction
BKM31_RS13200	COG1404	Belongs to the peptidase S8 family
BKM31_RS13220	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS13245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS13280	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS13285	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS13305	COG1609	Transcriptional regulator
BKM31_RS13310	COG3507	Belongs to the glycosyl hydrolase 43 family
BKM31_RS13315	COG3250	beta-galactosidase activity
BKM31_RS13330	COG1802	Transcriptional regulator
BKM31_RS13335	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS13345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKM31_RS13355	COG1414	Transcriptional regulator
BKM31_RS13365	COG1024	Enoyl-CoA hydratase
BKM31_RS13385	COG0657	acetylesterase activity
BKM31_RS13420	COG1082	Xylose isomerase domain protein TIM barrel
BKM31_RS13430	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS13435	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS13440	COG1129	ABC transporter
BKM31_RS13510	COG2826	transposase and inactivated derivatives, IS30 family
BKM31_RS13525	COG1609	Transcriptional regulator
BKM31_RS13530	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKM31_RS13530	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKM31_RS13550	COG4209	transmembrane transport
BKM31_RS13555	COG0395	ABC-type sugar transport system, permease component
BKM31_RS13595	COG0482	sulfurtransferase activity
BKM31_RS13650	COG0640	Transcriptional regulator
BKM31_RS13660	COG1846	Transcriptional regulator
BKM31_RS13660	COG1940	carbohydrate kinase activity
BKM31_RS13670	COG1175	transmembrane transport
BKM31_RS13680	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKM31_RS13690	COG1309	transcriptional regulator
BKM31_RS13695	COG1063	alcohol dehydrogenase
BKM31_RS13715	COG0302	gtp cyclohydrolase
BKM31_RS13720	COG0277	FAD linked oxidase domain protein
BKM31_RS13740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKM31_RS13740	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS13750	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS13785	COG3903	Transcriptional regulator
BKM31_RS13785	COG3629	intracellular signal transduction
BKM31_RS13790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKM31_RS13810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKM31_RS13820	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BKM31_RS13840	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BKM31_RS13860	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS13865	COG3403	YqcI/YcgG family
BKM31_RS13875	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BKM31_RS13890	COG3629	intracellular signal transduction
BKM31_RS13895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKM31_RS13905	COG4585	Histidine kinase
BKM31_RS13910	COG2197	response regulator
BKM31_RS13915	COG0656	L-ascorbic acid biosynthetic process
BKM31_RS13940	COG3467	pyridoxamine 5'-phosphate
BKM31_RS13950	COG0515	serine threonine protein kinase
BKM31_RS13950	COG2815	serine threonine protein kinase
BKM31_RS14065	COG4249	Peptidase C14 caspase catalytic subunit p20
BKM31_RS14065	COG2319	Wd-40 repeat
BKM31_RS14125	COG1309	transcriptional regulator
BKM31_RS14145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKM31_RS14175	COG0765	amino acid transport
BKM31_RS14180	COG1126	abc transporter atp-binding protein
BKM31_RS14185	COG0673	inositol 2-dehydrogenase activity
BKM31_RS14190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS14205	COG0604	alcohol dehydrogenase
BKM31_RS14225	COG1131	(ABC) transporter
BKM31_RS14230	COG1309	transcriptional regulator
BKM31_RS14245	COG1309	transcriptional regulator
BKM31_RS14250	COG4221	oxidoreductase activity
BKM31_RS14255	COG1309	transcriptional regulator
BKM31_RS14260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKM31_RS14285	COG0702	epimerase
BKM31_RS14290	COG1309	transcriptional regulator
BKM31_RS14310	COG0832	Belongs to the urease beta subunit family
BKM31_RS14310	COG0831	urea catabolic process
BKM31_RS14315	COG0804	urea catabolic process
BKM31_RS14320	COG0830	nickel cation binding
BKM31_RS14325	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BKM31_RS14330	COG0829	nickel cation binding
BKM31_RS14350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKM31_RS14360	COG0367	asparagine synthase
BKM31_RS14365	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS14390	COG0535	radical SAM domain protein
BKM31_RS14450	COG2226	methyltransferase
BKM31_RS14475	COG2197	response regulator
BKM31_RS14515	COG2197	response regulator
BKM31_RS14550	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKM31_RS14555	COG1309	transcriptional regulator
BKM31_RS14580	COG1309	transcriptional regulator
BKM31_RS14585	COG0604	alcohol dehydrogenase
BKM31_RS14585	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS14585	COG3321	synthase
BKM31_RS14610	COG2814	Major facilitator Superfamily
BKM31_RS14635	COG4974	Belongs to the 'phage' integrase family
BKM31_RS14710	COG0745	RESPONSE REGULATOR receiver
BKM31_RS14725	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BKM31_RS14740	COG3226	Transcriptional regulator
BKM31_RS14760	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKM31_RS14765	COG0745	RESPONSE REGULATOR receiver
BKM31_RS14770	COG2205	protein histidine kinase activity
BKM31_RS14920	COG4974	Belongs to the 'phage' integrase family
BKM31_RS15040	COG0596	Alpha beta hydrolase
BKM31_RS15050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKM31_RS15070	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS15090	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKM31_RS15100	COG1073	alpha beta
BKM31_RS15115	COG0702	epimerase
BKM31_RS15125	COG2045	Belongs to the ComB family
BKM31_RS15130	COG1309	transcriptional regulator
BKM31_RS15135	COG2124	cytochrome p450
BKM31_RS15180	COG1073	alpha beta
BKM31_RS15190	COG2197	response regulator
BKM31_RS15210	COG0667	Aldo Keto reductase
BKM31_RS15220	COG0789	Transcriptional regulator
BKM31_RS15240	COG1309	transcriptional regulator
BKM31_RS15250	COG2124	cytochrome p450
BKM31_RS15255	COG0667	Aldo Keto reductase
BKM31_RS15265	COG2814	Major facilitator Superfamily
BKM31_RS15280	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS15285	COG0583	DNA-binding transcription factor activity
BKM31_RS15330	COG2267	carboxylic ester hydrolase activity
BKM31_RS15405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKM31_RS15415	COG1268	BioY protein
BKM31_RS15425	COG0183	Belongs to the thiolase family
BKM31_RS15430	COG1122	ATPase activity
BKM31_RS15435	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BKM31_RS15440	COG0640	Transcriptional regulator
BKM31_RS15460	COG1309	transcriptional regulator
BKM31_RS15510	COG0640	Transcriptional regulator
BKM31_RS15520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKM31_RS15525	COG0586	Pfam SNARE associated Golgi protein
BKM31_RS15540	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKM31_RS15565	COG2814	Major facilitator Superfamily
BKM31_RS15615	COG1595	DNA-templated transcription, initiation
BKM31_RS15625	COG1309	transcriptional regulator
BKM31_RS15630	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS15635	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS15645	COG0504	CTP synthase activity
BKM31_RS15675	COG2814	Major facilitator Superfamily
BKM31_RS15695	COG0653	protein targeting
BKM31_RS15710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKM31_RS15715	COG1376	ErfK ybiS ycfS ynhG family protein
BKM31_RS15735	COG0477	Major facilitator Superfamily
BKM31_RS15745	COG2226	methyltransferase
BKM31_RS15755	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS15765	COG2197	response regulator
BKM31_RS15770	COG0667	Aldo Keto reductase
BKM31_RS15800	COG4974	Belongs to the 'phage' integrase family
BKM31_RS15810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKM31_RS15815	COG1024	Enoyl-CoA hydratase
BKM31_RS15815	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKM31_RS15865	COG2076	Multidrug Resistance protein
BKM31_RS15885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKM31_RS15910	COG0789	Transcriptional regulator
BKM31_RS15935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKM31_RS15960	COG3629	intracellular signal transduction
BKM31_RS15960	COG3903	Transcriptional regulator
BKM31_RS16070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKM31_RS16090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKM31_RS16245	COG0784	Response regulator, receiver
BKM31_RS16245	COG5002	protein histidine kinase activity
BKM31_RS16280	COG2188	Transcriptional regulator
BKM31_RS16310	COG0776	regulation of translation
BKM31_RS16380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKM31_RS16385	COG1846	Transcriptional regulator
BKM31_RS16415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKM31_RS16450	COG0791	NLP P60 protein
BKM31_RS16470	COG1486	melibiose metabolic process
BKM31_RS16475	COG1349	DNA-binding transcription factor activity
BKM31_RS16480	COG1486	melibiose metabolic process
BKM31_RS16495	COG1175	transmembrane transport
BKM31_RS16500	COG0395	ABC-type sugar transport system, permease component
BKM31_RS16505	COG2124	cytochrome p450
BKM31_RS16510	COG2124	cytochrome p450
BKM31_RS16520	COG0477	Major facilitator Superfamily
BKM31_RS16585	COG2188	Transcriptional regulator
BKM31_RS16595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS16610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS16615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS16620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS16625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS16630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKM31_RS16675	COG2197	response regulator
BKM31_RS16720	COG1175	transmembrane transport
BKM31_RS16755	COG0542	response to heat
BKM31_RS16780	COG4245	von Willebrand factor, type A
BKM31_RS16810	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKM31_RS16825	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS16835	COG0419	ATPase involved in DNA repair
BKM31_RS16840	COG0420	3'-5' exonuclease activity
BKM31_RS16900	COG1090	epimerase
BKM31_RS16905	COG1309	transcriptional regulator
BKM31_RS16930	COG0251	oxidation-reduction process
BKM31_RS16945	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKM31_RS16965	COG0477	Major facilitator Superfamily
BKM31_RS17015	COG0477	Major facilitator Superfamily
BKM31_RS17030	COG1609	Transcriptional regulator
BKM31_RS17040	COG1175	transmembrane transport
BKM31_RS17045	COG0395	ABC-type sugar transport system, permease component
BKM31_RS17090	COG0629	single-stranded DNA binding
BKM31_RS17155	COG4974	Belongs to the 'phage' integrase family
BKM31_RS17385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKM31_RS17385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKM31_RS17405	COG2226	methyltransferase
BKM31_RS17425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKM31_RS17430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKM31_RS17460	COG3328	transposase activity
BKM31_RS17470	COG2197	response regulator
BKM31_RS17475	COG2197	response regulator
BKM31_RS17500	COG3328	transposase activity
BKM31_RS17570	COG2319	Wd-40 repeat
BKM31_RS17570	COG4249	Peptidase C14 caspase catalytic subunit p20
BKM31_RS17575	COG4974	Belongs to the 'phage' integrase family
BKM31_RS17590	COG1234	tRNA 3'-trailer cleavage
BKM31_RS17600	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS17655	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS17690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKM31_RS17755	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BKM31_RS17790	COG3328	transposase activity
BKM31_RS17840	COG1169	isochorismate synthase
BKM31_RS17845	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS17860	COG0477	Major facilitator Superfamily
BKM31_RS17870	COG3903	Transcriptional regulator
BKM31_RS17870	COG3629	intracellular signal transduction
BKM31_RS17930	COG2226	methyltransferase
BKM31_RS17980	COG0791	NLP P60 protein
BKM31_RS17980	COG0741	lytic transglycosylase activity
BKM31_RS17990	COG1309	transcriptional regulator
BKM31_RS18005	COG2608	mercury ion transmembrane transporter activity
BKM31_RS18035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKM31_RS18035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKM31_RS18045	COG1937	Protein conserved in bacteria
BKM31_RS18085	COG1388	LysM domain
BKM31_RS18085	COG0791	NLP P60 protein
BKM31_RS18165	COG2217	Heavy metal translocating P-type atpase
BKM31_RS18175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKM31_RS18210	COG2217	Heavy metal translocating P-type atpase
BKM31_RS18220	COG2132	Multicopper oxidase
BKM31_RS18240	COG1136	(ABC) transporter
BKM31_RS18280	COG3415	Transposase
BKM31_RS18310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BKM31_RS18310	COG0517	IMP dehydrogenase activity
BKM31_RS18335	COG3620	sequence-specific DNA binding
BKM31_RS18335	COG0617	tRNA 3'-terminal CCA addition
BKM31_RS18335	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BKM31_RS18350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKM31_RS18360	COG0531	amino acid
BKM31_RS18370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BKM31_RS18395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKM31_RS18425	COG3344	reverse transcriptase
BKM31_RS18450	COG1140	nitrate reductase beta subunit
BKM31_RS18460	COG1017	nitric oxide dioxygenase activity
BKM31_RS18460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKM31_RS18480	COG1294	oxidase, subunit
BKM31_RS18485	COG1271	oxidase subunit
BKM31_RS18490	COG0517	IMP dehydrogenase activity
BKM31_RS18555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKM31_RS18575	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BKM31_RS18580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BKM31_RS18605	COG0640	Transcriptional regulator
BKM31_RS18610	COG2226	methyltransferase
BKM31_RS18615	COG0640	Transcriptional regulator
BKM31_RS18620	COG0798	PFAM Bile acid sodium symporter
BKM31_RS18625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKM31_RS18635	COG2234	aminopeptidase activity
BKM31_RS18650	COG2072	flavoprotein involved in K transport
BKM31_RS18670	COG2072	flavoprotein involved in K transport
BKM31_RS18760	COG1125	glycine betaine transport
BKM31_RS18760	COG0517	IMP dehydrogenase activity
BKM31_RS18765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKM31_RS18785	COG0330	HflC and HflK could
BKM31_RS18885	COG0745	RESPONSE REGULATOR receiver
BKM31_RS18890	COG2205	protein histidine kinase activity
BKM31_RS18895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKM31_RS18900	COG1830	Aldolase
BKM31_RS18905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKM31_RS18945	COG4109	DRTGG domain
BKM31_RS18950	COG2239	Acts as a magnesium transporter
BKM31_RS18980	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BKM31_RS18990	COG0674	pyruvate-flavodoxin oxidoreductase activity
BKM31_RS18995	COG1013	pyruvate-flavodoxin oxidoreductase activity
BKM31_RS19000	COG0493	'glutamate synthase
BKM31_RS19025	COG0439	Biotin carboxylase
BKM31_RS19030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKM31_RS19045	COG0517	IMP dehydrogenase activity
BKM31_RS19045	COG0516	GMP reductase activity
BKM31_RS19065	COG3259	Nickel-dependent hydrogenase
BKM31_RS19080	COG0409	Hydrogenase expression formation protein
BKM31_RS19085	COG0298	carbon dioxide binding
BKM31_RS19090	COG0589	response to stress
BKM31_RS19100	COG0589	response to stress
BKM31_RS19120	COG0517	IMP dehydrogenase activity
BKM31_RS19135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKM31_RS19160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKM31_RS19175	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BKM31_RS19215	COG0596	Alpha beta hydrolase
BKM31_RS19280	COG1309	transcriptional regulator
BKM31_RS19290	COG1309	transcriptional regulator
BKM31_RS19295	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKM31_RS19300	COG1131	(ABC) transporter
BKM31_RS19305	COG3559	Exporter of polyketide antibiotics
BKM31_RS19345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKM31_RS19365	COG2249	NAD(P)H dehydrogenase (quinone) activity
BKM31_RS19380	COG1510	regulation of RNA biosynthetic process
BKM31_RS19440	COG0142	geranyltranstransferase activity
BKM31_RS19450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS19455	COG1280	lysine exporter protein (LysE YggA)
BKM31_RS19470	COG2205	protein histidine kinase activity
BKM31_RS19475	COG0745	RESPONSE REGULATOR receiver
BKM31_RS19490	COG1136	(ABC) transporter
BKM31_RS19490	COG0577	efflux transmembrane transporter activity
BKM31_RS19495	COG1136	(ABC) transporter
BKM31_RS19495	COG0577	efflux transmembrane transporter activity
BKM31_RS19500	COG2197	response regulator
BKM31_RS19555	COG3250	beta-galactosidase activity
BKM31_RS19600	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS19605	COG2172	sigma factor antagonist activity
BKM31_RS19605	COG2208	phosphoserine phosphatase activity
BKM31_RS19605	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS19650	COG0506	proline dehydrogenase activity
BKM31_RS19655	COG1505	serine-type exopeptidase activity
BKM31_RS19735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKM31_RS19735	COG2226	methyltransferase
BKM31_RS19735	COG3433	isochorismatase activity
BKM31_RS19745	COG1696	Membrane protein involved in D-alanine export
BKM31_RS19760	COG0583	DNA-binding transcription factor activity
BKM31_RS19770	COG1522	sequence-specific DNA binding
BKM31_RS19795	COG3345	alpha-galactosidase
BKM31_RS19805	COG2226	methyltransferase
BKM31_RS19810	COG0640	Transcriptional regulator
BKM31_RS19820	COG3634	alkyl hydroperoxide reductase activity
BKM31_RS19840	COG0601	transmembrane transport
BKM31_RS19855	COG2226	methyltransferase
BKM31_RS19855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKM31_RS19855	COG3433	isochorismatase activity
BKM31_RS19855	COG3433	isochorismatase activity
BKM31_RS19855	COG2226	methyltransferase
BKM31_RS19855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKM31_RS19860	COG3321	synthase
BKM31_RS19860	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS19860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKM31_RS19860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM31_RS19860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKM31_RS19875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS19880	COG0789	Transcriptional regulator
BKM31_RS19925	COG2197	response regulator
BKM31_RS19990	COG1595	DNA-templated transcription, initiation
BKM31_RS20000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKM31_RS20010	COG3220	belongs to the UPF0276 family
BKM31_RS20040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKM31_RS20055	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS20055	COG0515	serine threonine protein kinase
BKM31_RS20090	COG0667	Aldo Keto reductase
BKM31_RS20125	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKM31_RS20140	COG0300	oxidoreductase activity
BKM31_RS20175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS20185	COG0604	alcohol dehydrogenase
BKM31_RS20200	COG0583	DNA-binding transcription factor activity
BKM31_RS20290	COG1175	transmembrane transport
BKM31_RS20295	COG0395	ABC-type sugar transport system, permease component
BKM31_RS20300	COG1621	beta-fructofuranosidase activity
BKM31_RS20305	COG1309	transcriptional regulator
BKM31_RS20385	COG1309	transcriptional regulator
BKM31_RS20405	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS20420	COG1175	transmembrane transport
BKM31_RS20425	COG0395	ABC-type sugar transport system, permease component
BKM31_RS20435	COG3250	beta-galactosidase activity
BKM31_RS20465	COG3345	alpha-galactosidase
BKM31_RS20470	COG1733	regulation of RNA biosynthetic process
BKM31_RS20485	COG2197	response regulator
BKM31_RS20505	COG0583	DNA-binding transcription factor activity
BKM31_RS20530	COG2197	response regulator
BKM31_RS20550	COG1404	Belongs to the peptidase S8 family
BKM31_RS20560	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS20570	COG0667	Aldo Keto reductase
BKM31_RS20585	COG1695	Transcriptional regulator
BKM31_RS20590	COG0577	efflux transmembrane transporter activity
BKM31_RS20590	COG1136	(ABC) transporter
BKM31_RS20600	COG1162	GTPase activity
BKM31_RS20620	COG2197	response regulator
BKM31_RS20630	COG2226	methyltransferase
BKM31_RS20675	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS20690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKM31_RS20735	COG0640	Transcriptional regulator
BKM31_RS20745	COG2814	Major facilitator Superfamily
BKM31_RS20755	COG1937	Protein conserved in bacteria
BKM31_RS20760	COG0791	NLP P60 protein
BKM31_RS20760	COG1388	LysM domain
BKM31_RS20765	COG1007	ATP synthesis coupled electron transport
BKM31_RS20770	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM31_RS20775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKM31_RS20800	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM31_RS20805	COG2720	vancomycin resistance protein
BKM31_RS20815	COG1116	anion transmembrane transporter activity
BKM31_RS20820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKM31_RS20825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKM31_RS20835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS20890	COG1404	Belongs to the peptidase S8 family
BKM31_RS20890	COG4412	M6 family metalloprotease domain protein
BKM31_RS20900	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS20905	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BKM31_RS20945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS20950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKM31_RS20955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKM31_RS20975	COG1609	Transcriptional regulator
BKM31_RS21000	COG3250	beta-galactosidase activity
BKM31_RS21005	COG2211	Major facilitator Superfamily
BKM31_RS21010	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS21015	COG3250	beta-galactosidase activity
BKM31_RS21020	COG1454	alcohol dehydrogenase
BKM31_RS21040	COG0395	ABC-type sugar transport system, permease component
BKM31_RS21045	COG1175	transmembrane transport
BKM31_RS21055	COG1802	Transcriptional regulator
BKM31_RS21060	COG0693	protein deglycase activity
BKM31_RS21080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKM31_RS21085	COG0243	molybdopterin cofactor binding
BKM31_RS21150	COG0475	glutathione-regulated potassium exporter activity
BKM31_RS21175	COG1396	sequence-specific DNA binding
BKM31_RS21180	COG0454	-acetyltransferase
BKM31_RS21190	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS21210	COG1309	transcriptional regulator
BKM31_RS21220	COG0300	oxidoreductase activity
BKM31_RS21230	COG0800	Aldolase
BKM31_RS21255	COG1414	Transcriptional regulator
BKM31_RS21260	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS21265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKM31_RS21270	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS21275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKM31_RS21285	COG3458	cephalosporin-C deacetylase activity
BKM31_RS21305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKM31_RS21320	COG1175	transmembrane transport
BKM31_RS21325	COG0395	ABC-type sugar transport system, permease component
BKM31_RS21355	COG2234	aminopeptidase activity
BKM31_RS21365	COG3509	depolymerase
BKM31_RS21405	COG2755	lipolytic protein G-D-S-L family
BKM31_RS21435	COG0477	Major facilitator Superfamily
BKM31_RS21440	COG0514	ATP-dependent DNA helicase (RecQ)
BKM31_RS21450	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKM31_RS21470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKM31_RS21475	COG0583	DNA-binding transcription factor activity
BKM31_RS21480	COG2851	Citrate transporter
BKM31_RS21495	COG2070	2-Nitropropane dioxygenase
BKM31_RS21510	COG4591	ABC-type transport system involved in lipoprotein release permease component
BKM31_RS21510	COG1136	(ABC) transporter
BKM31_RS21515	COG4591	ABC-type transport system involved in lipoprotein release permease component
BKM31_RS21515	COG1136	(ABC) transporter
BKM31_RS21530	COG1309	transcriptional regulator
BKM31_RS21540	COG1309	transcriptional regulator
BKM31_RS21560	COG0302	gtp cyclohydrolase
BKM31_RS21570	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BKM31_RS21575	COG0739	heme binding
BKM31_RS21655	COG1653	transport
BKM31_RS21660	COG1609	Transcriptional regulator
BKM31_RS21685	COG1280	lysine exporter protein (LysE YggA)
BKM31_RS21690	COG2197	response regulator
BKM31_RS21705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKM31_RS21710	COG0791	NLP P60 protein
BKM31_RS21710	COG3883	PFAM NLP P60 protein
BKM31_RS21725	COG0745	RESPONSE REGULATOR receiver
BKM31_RS21730	COG2205	protein histidine kinase activity
BKM31_RS21740	COG1278	Cold shock
BKM31_RS21755	COG3629	intracellular signal transduction
BKM31_RS21755	COG3903	Transcriptional regulator
BKM31_RS21765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS21775	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS21860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKM31_RS21870	COG0596	Alpha beta hydrolase
BKM31_RS21875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM31_RS21880	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS21890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKM31_RS21895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKM31_RS21915	COG0667	Aldo Keto reductase
BKM31_RS21925	COG2211	Major facilitator Superfamily
BKM31_RS21935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKM31_RS21980	COG0596	Alpha beta hydrolase
BKM31_RS22015	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKM31_RS22020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS22045	COG2267	carboxylic ester hydrolase activity
BKM31_RS22070	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS22075	COG1309	transcriptional regulator
BKM31_RS22080	COG1309	transcriptional regulator
BKM31_RS22085	COG0110	maltose O-acetyltransferase activity
BKM31_RS22095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKM31_RS22105	COG0577	efflux transmembrane transporter activity
BKM31_RS22105	COG1136	(ABC) transporter
BKM31_RS22125	COG1501	Belongs to the glycosyl hydrolase 31 family
BKM31_RS22130	COG1501	Belongs to the glycosyl hydrolase 31 family
BKM31_RS22135	COG1501	Belongs to the glycosyl hydrolase 31 family
BKM31_RS22140	COG3387	PFAM Glycoside hydrolase 15-related
BKM31_RS22150	COG0395	ABC-type sugar transport system, permease component
BKM31_RS22155	COG1175	transmembrane transport
BKM31_RS22160	COG1940	carbohydrate kinase activity
BKM31_RS22160	COG1846	Transcriptional regulator
BKM31_RS22170	COG1131	(ABC) transporter
BKM31_RS22175	COG4585	Histidine kinase
BKM31_RS22180	COG2197	response regulator
BKM31_RS22185	COG0009	L-threonylcarbamoyladenylate synthase
BKM31_RS22195	COG1309	transcriptional regulator
BKM31_RS22200	COG2326	polyphosphate kinase activity
BKM31_RS22205	COG4941	Belongs to the sigma-70 factor family
BKM31_RS22220	COG0367	asparagine synthase
BKM31_RS22230	COG1609	Transcriptional regulator
BKM31_RS22240	COG1175	transmembrane transport
BKM31_RS22245	COG0395	ABC-type sugar transport system, permease component
BKM31_RS22250	COG3250	beta-galactosidase activity
BKM31_RS22290	COG2197	response regulator
BKM31_RS22295	COG4585	Histidine kinase
BKM31_RS22310	COG3387	PFAM Glycoside hydrolase 15-related
BKM31_RS22320	COG1733	regulation of RNA biosynthetic process
BKM31_RS22330	COG0596	Alpha beta hydrolase
BKM31_RS22335	COG0494	nUDIX hydrolase
BKM31_RS22345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKM31_RS22370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKM31_RS22375	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKM31_RS22380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKM31_RS22390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKM31_RS22405	COG2197	response regulator
BKM31_RS22465	COG0459	protein refolding
BKM31_RS22470	COG1309	transcriptional regulator
BKM31_RS22505	COG1819	glycosyl
BKM31_RS22525	COG1733	regulation of RNA biosynthetic process
BKM31_RS22570	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS22575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS22575	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BKM31_RS22580	COG1177	transmembrane transport
BKM31_RS22590	COG3842	ATPase activity
BKM31_RS22610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKM31_RS22620	COG1116	anion transmembrane transporter activity
BKM31_RS22645	COG1414	Transcriptional regulator
BKM31_RS22660	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKM31_RS22660	COG1672	PFAM Archaeal ATPase
BKM31_RS22665	COG0596	Alpha beta hydrolase
BKM31_RS22670	COG0702	epimerase
BKM31_RS22675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS22680	COG1309	transcriptional regulator
BKM31_RS22685	COG0596	Alpha beta hydrolase
BKM31_RS22695	COG0702	epimerase
BKM31_RS22700	COG1309	transcriptional regulator
BKM31_RS22710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKM31_RS22735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS22740	COG1309	transcriptional regulator
BKM31_RS22760	COG0784	Response regulator, receiver
BKM31_RS22760	COG2205	protein histidine kinase activity
BKM31_RS22760	COG5002	protein histidine kinase activity
BKM31_RS22770	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
BKM31_RS22775	COG0308	aminopeptidase N
BKM31_RS22790	COG1846	Transcriptional regulator
BKM31_RS22795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKM31_RS22805	COG0302	gtp cyclohydrolase
BKM31_RS22815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKM31_RS22835	COG3226	Transcriptional regulator
BKM31_RS22840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKM31_RS22930	COG0667	Aldo Keto reductase
BKM31_RS22955	COG2084	Dehydrogenase
BKM31_RS22970	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS22975	COG2345	Transcriptional regulator
BKM31_RS22985	COG2226	methyltransferase
BKM31_RS23015	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS23025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS23040	COG2124	cytochrome p450
BKM31_RS23045	COG2192	nodulation
BKM31_RS23050	COG1819	glycosyl
BKM31_RS23065	COG0662	Cupin 2, conserved barrel domain protein
BKM31_RS23070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKM31_RS23080	COG0439	Biotin carboxylase
BKM31_RS23085	COG0511	ligase activity, forming carbon-carbon bonds
BKM31_RS23090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKM31_RS23090	COG0825	malonyl-CoA metabolic process
BKM31_RS23105	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS23110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKM31_RS23115	COG3104	oligopeptide transport
BKM31_RS23140	COG0725	ABC transporter, periplasmic molybdate-binding protein
BKM31_RS23170	COG4585	Histidine kinase
BKM31_RS23175	COG1131	(ABC) transporter
BKM31_RS23200	COG2197	response regulator
BKM31_RS23205	COG4585	Histidine kinase
BKM31_RS23220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKM31_RS23240	COG2409	Drug exporters of the RND superfamily
BKM31_RS23250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM31_RS23260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKM31_RS23265	COG0156	8-amino-7-oxononanoate synthase activity
BKM31_RS23290	COG1280	lysine exporter protein (LysE YggA)
BKM31_RS23295	COG2378	regulation of single-species biofilm formation
BKM31_RS23305	COG0738	Major facilitator superfamily
BKM31_RS23330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKM31_RS23335	COG0640	Transcriptional regulator
BKM31_RS23340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKM31_RS23385	COG0395	ABC-type sugar transport system, permease component
BKM31_RS23390	COG1501	Belongs to the glycosyl hydrolase 31 family
BKM31_RS23395	COG0738	Major facilitator superfamily
BKM31_RS23435	COG1609	Transcriptional regulator
BKM31_RS23440	COG1309	transcriptional regulator
BKM31_RS23445	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS23465	COG2211	Major facilitator Superfamily
BKM31_RS23470	COG3250	beta-galactosidase activity
BKM31_RS23475	COG3250	beta-galactosidase activity
BKM31_RS23495	COG0395	ABC-type sugar transport system, permease component
BKM31_RS23505	COG2182	Extracellular solute-binding protein
BKM31_RS23510	COG1737	Transcriptional regulator
BKM31_RS23515	COG0737	Belongs to the 5'-nucleotidase family
BKM31_RS23520	COG0395	ABC-type sugar transport system, permease component
BKM31_RS23525	COG1175	transmembrane transport
BKM31_RS23560	COG1940	carbohydrate kinase activity
BKM31_RS23560	COG1846	Transcriptional regulator
BKM31_RS23565	COG1940	carbohydrate kinase activity
BKM31_RS23570	COG3507	Belongs to the glycosyl hydrolase 43 family
BKM31_RS23595	COG2814	Major facilitator Superfamily
BKM31_RS23600	COG2814	Major facilitator Superfamily
BKM31_RS23685	COG3629	intracellular signal transduction
BKM31_RS23685	COG3903	Transcriptional regulator
BKM31_RS23715	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BKM31_RS23730	COG2207	Transcriptional regulator
BKM31_RS23740	COG0740	serine-type endopeptidase activity
BKM31_RS23745	COG0740	serine-type endopeptidase activity
BKM31_RS23750	COG4585	Histidine kinase
BKM31_RS23755	COG2197	response regulator
BKM31_RS23760	COG5504	Zn-dependent protease
BKM31_RS23770	COG0714	Associated with various cellular activities
BKM31_RS23780	COG2304	oxidoreductase activity
BKM31_RS23785	COG2813	Specifically methylates the guanine in position
BKM31_RS23790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKM31_RS23815	COG1733	regulation of RNA biosynthetic process
BKM31_RS23850	COG4585	Histidine kinase
BKM31_RS23855	COG2197	response regulator
BKM31_RS23860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKM31_RS23885	COG0463	Glycosyl transferase, family 2
BKM31_RS23895	COG3973	AAA domain
BKM31_RS23915	COG0395	ABC-type sugar transport system, permease component
BKM31_RS23920	COG1486	melibiose metabolic process
BKM31_RS23930	COG1522	sequence-specific DNA binding
BKM31_RS23965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKM31_RS23970	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BKM31_RS23975	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS23990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKM31_RS24025	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKM31_RS24025	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKM31_RS24045	COG1716	ATPase activity
BKM31_RS24050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKM31_RS24065	COG0135	phosphoribosylanthranilate isomerase activity
BKM31_RS24075	COG2197	response regulator
BKM31_RS24095	COG0657	acetylesterase activity
BKM31_RS24100	COG0504	CTP synthase activity
BKM31_RS24155	COG2124	cytochrome p450
BKM31_RS24160	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS24165	COG1309	transcriptional regulator
BKM31_RS24170	COG1404	Belongs to the peptidase S8 family
BKM31_RS24170	COG4412	M6 family metalloprotease domain protein
BKM31_RS24235	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS24245	COG1309	transcriptional regulator
BKM31_RS24280	COG0084	hydrolase, TatD family'
BKM31_RS24295	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BKM31_RS24305	COG0395	ABC-type sugar transport system, permease component
BKM31_RS24310	COG1175	transmembrane transport
BKM31_RS24330	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS24340	COG0281	malic enzyme
BKM31_RS24380	COG0477	Major facilitator Superfamily
BKM31_RS24385	COG1309	transcriptional regulator
BKM31_RS24400	COG0248	Ppx GppA phosphatase
BKM31_RS24410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKM31_RS24415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKM31_RS24435	COG2409	Drug exporters of the RND superfamily
BKM31_RS24445	COG2197	response regulator
BKM31_RS24450	COG4585	Histidine kinase
BKM31_RS24455	COG1131	(ABC) transporter
BKM31_RS24460	COG0842	Transport permease protein
BKM31_RS24465	COG4585	Histidine kinase
BKM31_RS24470	COG2197	response regulator
BKM31_RS24475	COG0745	RESPONSE REGULATOR receiver
BKM31_RS24480	COG2205	protein histidine kinase activity
BKM31_RS24505	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BKM31_RS24530	COG2890	protein-(glutamine-N5) methyltransferase activity
BKM31_RS24535	COG0242	peptide deformylase activity
BKM31_RS24545	COG0076	glutamate decarboxylase activity
BKM31_RS24550	COG0517	IMP dehydrogenase activity
BKM31_RS24590	COG1349	DNA-binding transcription factor activity
BKM31_RS24615	COG1063	alcohol dehydrogenase
BKM31_RS24625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKM31_RS24630	COG0542	response to heat
BKM31_RS24635	COG0702	epimerase
BKM31_RS24640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKM31_RS24645	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BKM31_RS24660	COG0596	Alpha beta hydrolase
BKM31_RS24675	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
BKM31_RS24690	COG1486	melibiose metabolic process
BKM31_RS24695	COG1349	DNA-binding transcription factor activity
BKM31_RS24710	COG1175	transmembrane transport
BKM31_RS24735	COG1505	serine-type exopeptidase activity
BKM31_RS24750	COG3629	intracellular signal transduction
BKM31_RS24765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS24775	COG1309	transcriptional regulator
BKM31_RS24800	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS24805	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS24810	COG1129	ABC transporter
BKM31_RS24815	COG1879	ABC-type sugar transport system periplasmic component
BKM31_RS24820	COG2133	pyrroloquinoline quinone binding
BKM31_RS24820	COG5183	chlorophyll binding
BKM31_RS24830	COG1129	ABC transporter
BKM31_RS24875	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS24885	COG1175	transmembrane transport
BKM31_RS24900	COG0745	RESPONSE REGULATOR receiver
BKM31_RS24905	COG2205	protein histidine kinase activity
BKM31_RS24935	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS24945	COG0444	Belongs to the ABC transporter superfamily
BKM31_RS24965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKM31_RS24995	COG2124	cytochrome p450
BKM31_RS25005	COG3833	ABC-type maltose transport systems, permease component
BKM31_RS25035	COG1280	lysine exporter protein (LysE YggA)
BKM31_RS25055	COG0166	Belongs to the GPI family
BKM31_RS25065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKM31_RS25070	COG4585	Histidine kinase
BKM31_RS25080	COG2201	protein-glutamate methylesterase activity
BKM31_RS25085	COG0490	domain, Protein
BKM31_RS25110	COG0431	NADPH-dependent FMN reductase
BKM31_RS25115	COG0667	Aldo Keto reductase
BKM31_RS25145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS25200	COG3458	cephalosporin-C deacetylase activity
BKM31_RS25210	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKM31_RS25255	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS25265	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS25270	COG3191	aminopeptidase activity
BKM31_RS25275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKM31_RS25280	COG4608	Belongs to the ABC transporter superfamily
BKM31_RS25290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS25300	COG0747	negative chemotaxis
BKM31_RS25305	COG2186	Transcriptional regulator
BKM31_RS25310	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKM31_RS25315	COG1595	DNA-templated transcription, initiation
BKM31_RS25330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS25335	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS25340	COG2226	methyltransferase
BKM31_RS25365	COG0583	DNA-binding transcription factor activity
BKM31_RS25380	COG2130	NADP-dependent
BKM31_RS25400	COG0656	L-ascorbic acid biosynthetic process
BKM31_RS25410	COG2197	response regulator
BKM31_RS25415	COG4585	Histidine kinase
BKM31_RS25455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKM31_RS25460	COG1126	abc transporter atp-binding protein
BKM31_RS25465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKM31_RS25470	COG0765	amino acid transport
BKM31_RS25475	COG0765	amino acid transport
BKM31_RS25480	COG0154	amidase activity
BKM31_RS25490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKM31_RS25495	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKM31_RS25510	COG0584	glycerophosphoryl diester phosphodiesterase
BKM31_RS25525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKM31_RS25530	COG2133	pyrroloquinoline quinone binding
BKM31_RS25535	COG2197	response regulator
BKM31_RS25545	COG1404	Belongs to the peptidase S8 family
BKM31_RS25550	COG1609	Transcriptional regulator
BKM31_RS25575	COG1879	ABC-type sugar transport system periplasmic component
BKM31_RS25585	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS25590	COG1129	ABC transporter
BKM31_RS25625	COG2111	Na H antiporter
BKM31_RS25625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKM31_RS25630	COG1006	Multisubunit Na H antiporter MnhC subunit
BKM31_RS25635	COG0651	ATP synthesis coupled electron transport
BKM31_RS25660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKM31_RS25665	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKM31_RS25670	COG2080	2 iron, 2 sulfur cluster binding
BKM31_RS25675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKM31_RS25685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKM31_RS25690	COG0247	lactate metabolic process
BKM31_RS25690	COG0277	FAD linked oxidase domain protein
BKM31_RS25695	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BKM31_RS25710	COG0596	Alpha beta hydrolase
BKM31_RS25720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKM31_RS25725	COG0569	domain protein
BKM31_RS25730	COG0789	Transcriptional regulator
BKM31_RS25760	COG4977	sequence-specific DNA binding
BKM31_RS25775	COG1136	(ABC) transporter
BKM31_RS25785	COG2366	antibiotic biosynthetic process
BKM31_RS25815	COG0784	Response regulator, receiver
BKM31_RS25815	COG5002	protein histidine kinase activity
BKM31_RS25815	COG2205	protein histidine kinase activity
BKM31_RS25865	COG2814	Major facilitator Superfamily
BKM31_RS25870	COG1309	transcriptional regulator
BKM31_RS25875	COG0667	Aldo Keto reductase
BKM31_RS25920	COG0730	response to heat
BKM31_RS25960	COG0019	diaminopimelate decarboxylase activity
BKM31_RS25980	COG0477	Major facilitator Superfamily
BKM31_RS25985	COG1309	transcriptional regulator
BKM31_RS25990	COG0463	Glycosyl transferase, family 2
BKM31_RS26000	COG2409	Drug exporters of the RND superfamily
BKM31_RS26005	COG0667	Aldo Keto reductase
BKM31_RS26015	COG1803	Methylglyoxal synthase
BKM31_RS26015	COG1597	lipid kinase activity
BKM31_RS26055	COG1131	(ABC) transporter
BKM31_RS26065	COG1595	DNA-templated transcription, initiation
BKM31_RS26090	COG1131	(ABC) transporter
BKM31_RS26110	COG0745	RESPONSE REGULATOR receiver
BKM31_RS26115	COG2205	protein histidine kinase activity
BKM31_RS26130	COG1316	TRANSCRIPTIONal
BKM31_RS26145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BKM31_RS26165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKM31_RS26190	COG0488	(ABC) transporter
BKM31_RS26200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BKM31_RS26205	COG0129	dihydroxy-acid dehydratase activity
BKM31_RS26210	COG0837	glucose binding
BKM31_RS26215	COG0800	Aldolase
BKM31_RS26225	COG0477	Major facilitator Superfamily
BKM31_RS26255	COG1414	Transcriptional regulator
BKM31_RS26265	COG0515	serine threonine protein kinase
BKM31_RS26265	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS26285	COG0800	Aldolase
BKM31_RS26295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKM31_RS26305	COG0366	Alpha amylase catalytic
BKM31_RS26315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKM31_RS26340	COG0640	Transcriptional regulator
BKM31_RS26345	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS26350	COG2030	dehydratase
BKM31_RS26385	COG3833	ABC-type maltose transport systems, permease component
BKM31_RS26390	COG1175	transmembrane transport
BKM31_RS26400	COG0366	Alpha amylase catalytic
BKM31_RS26405	COG2205	protein histidine kinase activity
BKM31_RS26415	COG1301	dicarboxylic acid transport
BKM31_RS26420	COG3290	protein histidine kinase activity
BKM31_RS26425	COG4565	transcriptional regulatory protein
BKM31_RS26430	COG2089	acid synthase
BKM31_RS26435	COG1216	Glycosyl transferase, family 2
BKM31_RS26455	COG0656	L-ascorbic acid biosynthetic process
BKM31_RS26485	COG1132	(ABC) transporter
BKM31_RS26490	COG2274	protein secretion by the type I secretion system
BKM31_RS26495	COG1309	transcriptional regulator
BKM31_RS26510	COG1404	Belongs to the peptidase S8 family
BKM31_RS26530	COG4941	Belongs to the sigma-70 factor family
BKM31_RS26550	COG1175	transmembrane transport
BKM31_RS26555	COG0395	ABC-type sugar transport system, permease component
BKM31_RS26590	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BKM31_RS26600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKM31_RS26615	COG0640	Transcriptional regulator
BKM31_RS26635	COG1271	oxidase subunit
BKM31_RS26640	COG1294	oxidase, subunit
BKM31_RS26645	COG4988	ABC transporter
BKM31_RS26650	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BKM31_RS26690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKM31_RS26705	COG2011	ABC-type metal ion transport system permease component
BKM31_RS26710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKM31_RS26715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKM31_RS26725	COG3850	Histidine kinase
BKM31_RS26730	COG2197	response regulator
BKM31_RS26760	COG5002	protein histidine kinase activity
BKM31_RS26760	COG0784	Response regulator, receiver
BKM31_RS26760	COG2198	Histidine kinase
BKM31_RS26770	COG2172	sigma factor antagonist activity
BKM31_RS26775	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS26780	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS26790	COG5398	heme oxygenase
BKM31_RS26795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKM31_RS26800	COG0477	Major facilitator Superfamily
BKM31_RS26815	COG2205	protein histidine kinase activity
BKM31_RS26820	COG0745	RESPONSE REGULATOR receiver
BKM31_RS26830	COG1136	(ABC) transporter
BKM31_RS26830	COG0577	efflux transmembrane transporter activity
BKM31_RS26835	COG0577	efflux transmembrane transporter activity
BKM31_RS26835	COG1136	(ABC) transporter
BKM31_RS26840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKM31_RS26850	COG3540	Alkaline phosphatase
BKM31_RS26865	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKM31_RS26870	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS26875	COG1309	transcriptional regulator
BKM31_RS26910	COG1473	amidohydrolase
BKM31_RS26930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS26935	COG0444	Belongs to the ABC transporter superfamily
BKM31_RS26940	COG4608	Belongs to the ABC transporter superfamily
BKM31_RS26950	COG3876	Protein conserved in bacteria
BKM31_RS26955	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BKM31_RS26960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS26965	COG2814	Major facilitator Superfamily
BKM31_RS26975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKM31_RS26980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS27000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKM31_RS27055	COG0488	(ABC) transporter
BKM31_RS27065	COG1022	Amp-dependent synthetase and ligase
BKM31_RS27070	COG0824	Thioesterase
BKM31_RS27120	COG0235	Class ii aldolase
BKM31_RS27120	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BKM31_RS27150	COG0657	acetylesterase activity
BKM31_RS27155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKM31_RS27195	COG0598	Magnesium transport protein CorA
BKM31_RS27215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKM31_RS27220	COG2197	response regulator
BKM31_RS27235	COG3795	YCII-related domain
BKM31_RS27240	COG4941	Belongs to the sigma-70 factor family
BKM31_RS27245	COG2124	cytochrome p450
BKM31_RS27255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKM31_RS27255	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BKM31_RS27260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKM31_RS27270	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS27275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKM31_RS27280	COG0583	DNA-binding transcription factor activity
BKM31_RS27300	COG0589	response to stress
BKM31_RS27305	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS27315	COG2186	Transcriptional regulator
BKM31_RS27365	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKM31_RS27375	COG1414	Transcriptional regulator
BKM31_RS27395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS27460	COG0297	glycogen (starch) synthase activity
BKM31_RS27465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKM31_RS27475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKM31_RS27485	COG0506	proline dehydrogenase activity
BKM31_RS27490	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS27495	COG4977	sequence-specific DNA binding
BKM31_RS27515	COG0515	serine threonine protein kinase
BKM31_RS27530	COG2376	Dihydroxyacetone kinase
BKM31_RS27535	COG1461	Dihydroxyacetone kinase
BKM31_RS27550	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BKM31_RS27565	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BKM31_RS27570	COG0006	proline dipeptidase activity
BKM31_RS27575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKM31_RS27580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKM31_RS27645	COG0477	Major facilitator Superfamily
BKM31_RS27650	COG0477	Major facilitator Superfamily
BKM31_RS27655	COG0017	Asparaginyl-tRNA synthetase
BKM31_RS27660	COG1160	GTP binding
BKM31_RS27665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKM31_RS27695	COG1252	NADH dehydrogenase
BKM31_RS27730	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKM31_RS27735	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BKM31_RS27750	COG0494	nUDIX hydrolase
BKM31_RS27755	COG0504	CTP synthase activity
BKM31_RS27765	COG2070	2-Nitropropane dioxygenase
BKM31_RS27770	COG2186	Transcriptional regulator
BKM31_RS27820	COG0596	Alpha beta hydrolase
BKM31_RS27830	COG0556	nucleotide-excision repair
BKM31_RS27835	COG1476	TRANSCRIPTIONal
BKM31_RS27880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKM31_RS27885	COG2319	Wd-40 repeat
BKM31_RS27885	COG5635	Nacht domain
BKM31_RS27890	COG0237	dephospho-CoA kinase activity
BKM31_RS27910	COG0596	Alpha beta hydrolase
BKM31_RS27915	COG0539	negative regulation of cytoplasmic translation
BKM31_RS27930	COG2050	protein possibly involved in aromatic compounds catabolism
BKM31_RS27935	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS27990	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS27995	COG0583	DNA-binding transcription factor activity
BKM31_RS28035	COG0667	Aldo Keto reductase
BKM31_RS28050	COG0069	glutamate synthase activity
BKM31_RS28050	COG0067	glutamate synthase
BKM31_RS28050	COG0070	glutamate synthase
BKM31_RS28080	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKM31_RS28105	COG0366	Alpha amylase catalytic
BKM31_RS28105	COG1470	cell adhesion involved in biofilm formation
BKM31_RS28110	COG0159	tryptophan synthase activity
BKM31_RS28115	COG0133	tryptophan synthase activity
BKM31_RS28120	COG0134	indole-3-glycerol-phosphate synthase activity
BKM31_RS28145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKM31_RS28150	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS28165	COG1132	(ABC) transporter
BKM31_RS28170	COG1132	(ABC) transporter
BKM31_RS28185	COG0107	imidazoleglycerol-phosphate synthase activity
BKM31_RS28190	COG0251	oxidation-reduction process
BKM31_RS28195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKM31_RS28205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKM31_RS28210	COG0131	Imidazoleglycerol-phosphate dehydratase
BKM31_RS28215	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKM31_RS28220	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKM31_RS28235	COG1793	dna ligase
BKM31_RS28235	COG3285	dna ligase
BKM31_RS28245	COG2223	nitrite transmembrane transporter activity
BKM31_RS28255	COG2207	Transcriptional regulator
BKM31_RS28260	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKM31_RS28265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKM31_RS28270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKM31_RS28285	COG0587	DNA-directed DNA polymerase activity
BKM31_RS28290	COG1113	amino acid transport
BKM31_RS28305	COG2815	serine threonine protein kinase
BKM31_RS28305	COG0515	serine threonine protein kinase
BKM31_RS28330	COG0515	serine threonine protein kinase
BKM31_RS28340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKM31_RS28350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKM31_RS28375	COG3599	regulation of cell shape
BKM31_RS28385	COG1799	cell septum assembly
BKM31_RS28395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BKM31_RS28400	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKM31_RS28405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKM31_RS28410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKM31_RS28420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKM31_RS28425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKM31_RS28435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKM31_RS28440	COG0768	penicillin binding
BKM31_RS28450	COG0275	rRNA processing
BKM31_RS28455	COG2001	Belongs to the MraZ family
BKM31_RS28460	COG0714	Associated with various cellular activities
BKM31_RS28480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKM31_RS28490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKM31_RS28495	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKM31_RS28500	COG0006	proline dipeptidase activity
BKM31_RS28505	COG2815	serine threonine protein kinase
BKM31_RS28505	COG0515	serine threonine protein kinase
BKM31_RS28515	COG3655	Transcriptional regulator
BKM31_RS28520	COG1301	dicarboxylic acid transport
BKM31_RS28525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS28540	COG3608	succinylglutamate desuccinylase aspartoacylase
BKM31_RS28540	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BKM31_RS28550	COG0542	response to heat
BKM31_RS28565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BKM31_RS28570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKM31_RS28570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKM31_RS28575	COG3201	nicotinamide mononucleotide transporter
BKM31_RS28595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BKM31_RS28600	COG0671	phosphoesterase, PA-phosphatase related
BKM31_RS28610	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKM31_RS28615	COG0242	peptide deformylase activity
BKM31_RS28630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKM31_RS28640	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKM31_RS28655	COG1758	RNA polymerase activity
BKM31_RS28660	COG0194	GDP metabolic process
BKM31_RS28670	COG0284	orotidine-5'-phosphate decarboxylase activity
BKM31_RS28675	COG0167	dihydroorotate dehydrogenase activity
BKM31_RS28680	COG0543	2 iron, 2 sulfur cluster binding
BKM31_RS28685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKM31_RS28690	COG0505	Belongs to the CarA family
BKM31_RS28695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKM31_RS28700	COG0540	Belongs to the ATCase OTCase family
BKM31_RS28705	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BKM31_RS28715	COG0549	Belongs to the carbamate kinase family
BKM31_RS28750	COG1309	transcriptional regulator
BKM31_RS28785	COG0456	acetyltransferase
BKM31_RS28795	COG0142	geranyltranstransferase activity
BKM31_RS28800	COG0352	thiamine-phosphate diphosphorylase activity
BKM31_RS28815	COG2022	thiamine diphosphate biosynthetic process
BKM31_RS28815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS28825	COG2022	thiamine diphosphate biosynthetic process
BKM31_RS28830	COG2815	serine threonine protein kinase
BKM31_RS28830	COG0515	serine threonine protein kinase
BKM31_RS28835	COG4266	Belongs to the allantoicase family
BKM31_RS28840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKM31_RS28845	COG1929	Belongs to the glycerate kinase type-1 family
BKM31_RS28885	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BKM31_RS28890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKM31_RS28900	COG3279	Response regulator of the LytR AlgR family
BKM31_RS28905	COG3275	phosphorelay sensor kinase activity
BKM31_RS28910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKM31_RS28915	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BKM31_RS28925	COG0301	tRNA thio-modification
BKM31_RS28930	COG2197	response regulator
BKM31_RS28950	COG0205	6-phosphofructokinase activity
BKM31_RS28970	COG1846	Transcriptional regulator
BKM31_RS28970	COG0456	acetyltransferase
BKM31_RS28975	COG2409	Drug exporters of the RND superfamily
BKM31_RS28980	COG1309	transcriptional regulator
BKM31_RS29015	COG2040	homocysteine
BKM31_RS29030	COG2259	Doxx family
BKM31_RS29040	COG0204	Acyl-transferase
BKM31_RS29065	COG1940	carbohydrate kinase activity
BKM31_RS29075	COG0003	Pfam Anion-transporting ATPase
BKM31_RS29095	COG0789	Transcriptional regulator
BKM31_RS29100	COG0667	Aldo Keto reductase
BKM31_RS29110	COG2124	cytochrome p450
BKM31_RS29120	COG1175	transmembrane transport
BKM31_RS29125	COG0395	ABC-type sugar transport system, permease component
BKM31_RS29130	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS29135	COG0501	Belongs to the peptidase M48B family
BKM31_RS29145	COG0791	NLP P60 protein
BKM31_RS29165	COG2197	response regulator
BKM31_RS29195	COG0515	serine threonine protein kinase
BKM31_RS29200	COG0515	serine threonine protein kinase
BKM31_RS29215	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKM31_RS29220	COG0723	plastoquinol--plastocyanin reductase activity
BKM31_RS29225	COG2010	Cytochrome c
BKM31_RS29230	COG1845	cytochrome c oxidase, subunit III
BKM31_RS29245	COG1376	ErfK ybiS ycfS ynhG family protein
BKM31_RS29255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKM31_RS29260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKM31_RS29265	COG1104	cysteine desulfurase activity
BKM31_RS29270	COG0425	Belongs to the sulfur carrier protein TusA family
BKM31_RS29280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKM31_RS29290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BKM31_RS29315	COG0501	Belongs to the peptidase M48B family
BKM31_RS29340	COG0667	Aldo Keto reductase
BKM31_RS29355	COG1119	ATPase activity
BKM31_RS29360	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BKM31_RS29375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS29380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKM31_RS29385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKM31_RS29405	COG0321	lipoyl(octanoyl) transferase activity
BKM31_RS29415	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKM31_RS29445	COG0596	Alpha beta hydrolase
BKM31_RS29445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKM31_RS29445	COG2226	methyltransferase
BKM31_RS29455	COG1309	transcriptional regulator
BKM31_RS29505	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BKM31_RS29530	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKM31_RS29535	COG0174	glutamine synthetase
BKM31_RS29545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKM31_RS29555	COG2814	Major facilitator Superfamily
BKM31_RS29575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKM31_RS29575	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKM31_RS29580	COG0640	Transcriptional regulator
BKM31_RS29590	COG4335	DNA alkylation repair
BKM31_RS29670	COG0477	Major facilitator Superfamily
BKM31_RS29680	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKM31_RS29685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKM31_RS29690	COG0626	cystathionine gamma-synthase activity
BKM31_RS29695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS29705	COG1131	(ABC) transporter
BKM31_RS29720	COG2197	response regulator
BKM31_RS29740	COG0583	DNA-binding transcription factor activity
BKM31_RS29795	COG2252	PERMEase
BKM31_RS29810	COG0445	tRNA wobble uridine modification
BKM31_RS29845	COG2197	response regulator
BKM31_RS29850	COG0515	serine threonine protein kinase
BKM31_RS29850	COG2815	serine threonine protein kinase
BKM31_RS29875	COG1120	ATPase activity
BKM31_RS29880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKM31_RS29885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKM31_RS29890	COG0673	inositol 2-dehydrogenase activity
BKM31_RS29895	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS29900	COG2124	cytochrome p450
BKM31_RS29925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS29930	COG0406	alpha-ribazole phosphatase activity
BKM31_RS29980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKM31_RS29985	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKM31_RS29990	COG1120	ATPase activity
BKM31_RS30000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS30005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKM31_RS30015	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKM31_RS30040	COG4585	Histidine kinase
BKM31_RS30045	COG2197	response regulator
BKM31_RS30060	COG1309	transcriptional regulator
BKM31_RS30065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKM31_RS30070	COG4336	lyase activity
BKM31_RS30075	COG1733	regulation of RNA biosynthetic process
BKM31_RS30085	COG0714	Associated with various cellular activities
BKM31_RS30090	COG3864	Putative metallopeptidase domain
BKM31_RS30140	COG2124	cytochrome p450
BKM31_RS30155	COG1233	COG1233 Phytoene dehydrogenase and related
BKM31_RS30195	COG0243	molybdopterin cofactor binding
BKM31_RS30200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKM31_RS30250	COG1175	transmembrane transport
BKM31_RS30255	COG0395	ABC-type sugar transport system, permease component
BKM31_RS30270	COG5434	Belongs to the glycosyl hydrolase 28 family
BKM31_RS30330	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS30340	COG2986	histidine ammonia-lyase
BKM31_RS30345	COG0395	ABC-type sugar transport system, permease component
BKM31_RS30350	COG1175	transmembrane transport
BKM31_RS30355	COG2182	Extracellular solute-binding protein
BKM31_RS30365	COG3250	beta-galactosidase activity
BKM31_RS30400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKM31_RS30405	COG1414	Transcriptional regulator
BKM31_RS30420	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS30425	COG1063	alcohol dehydrogenase
BKM31_RS30445	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS30450	COG0583	DNA-binding transcription factor activity
BKM31_RS30455	COG1309	transcriptional regulator
BKM31_RS30460	COG1309	transcriptional regulator
BKM31_RS30465	COG2226	methyltransferase
BKM31_RS30485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKM31_RS30515	COG0395	ABC-type sugar transport system, permease component
BKM31_RS30520	COG4209	transmembrane transport
BKM31_RS30530	COG2814	Major facilitator Superfamily
BKM31_RS30580	COG2409	Drug exporters of the RND superfamily
BKM31_RS30585	COG1309	transcriptional regulator
BKM31_RS30655	COG2124	cytochrome p450
BKM31_RS30660	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BKM31_RS30660	COG3608	succinylglutamate desuccinylase aspartoacylase
BKM31_RS30670	COG3534	alpha-L-arabinofuranosidase
BKM31_RS30680	COG1120	ATPase activity
BKM31_RS30710	COG2986	histidine ammonia-lyase
BKM31_RS30775	COG0156	8-amino-7-oxononanoate synthase activity
BKM31_RS30780	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS30845	COG0477	Major facilitator Superfamily
BKM31_RS30855	COG1609	Transcriptional regulator
BKM31_RS30870	COG1175	transmembrane transport
BKM31_RS30875	COG0395	ABC-type sugar transport system, permease component
BKM31_RS30880	COG0488	(ABC) transporter
BKM31_RS30915	COG1309	transcriptional regulator
BKM31_RS30920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKM31_RS30925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKM31_RS30930	COG3485	protocatechuate 3,4-dioxygenase
BKM31_RS30935	COG3485	protocatechuate 3,4-dioxygenase
BKM31_RS30940	COG0183	Belongs to the thiolase family
BKM31_RS30955	COG1414	Transcriptional regulator
BKM31_RS30965	COG0277	FAD linked oxidase domain protein
BKM31_RS30970	COG2080	2 iron, 2 sulfur cluster binding
BKM31_RS30975	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKM31_RS30985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKM31_RS30990	COG0671	phosphoesterase, PA-phosphatase related
BKM31_RS31005	COG0515	serine threonine protein kinase
BKM31_RS31035	COG4977	sequence-specific DNA binding
BKM31_RS31065	COG1404	Belongs to the peptidase S8 family
BKM31_RS31160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKM31_RS31165	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BKM31_RS31170	COG0121	glutamine amidotransferase
BKM31_RS31175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKM31_RS31200	COG0861	Integral membrane protein TerC family
BKM31_RS31215	COG0076	glutamate decarboxylase activity
BKM31_RS31250	COG1609	Transcriptional regulator
BKM31_RS31280	COG2197	response regulator
BKM31_RS31310	COG0395	ABC-type sugar transport system, permease component
BKM31_RS31315	COG4209	transmembrane transport
BKM31_RS31320	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS31325	COG3629	intracellular signal transduction
BKM31_RS31325	COG3903	Transcriptional regulator
BKM31_RS31330	COG0596	Alpha beta hydrolase
BKM31_RS31370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKM31_RS31375	COG0247	lactate metabolic process
BKM31_RS31375	COG0277	FAD linked oxidase domain protein
BKM31_RS31405	COG2274	protein secretion by the type I secretion system
BKM31_RS31415	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS31470	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS31480	COG0477	Major facilitator Superfamily
BKM31_RS31490	COG4941	Belongs to the sigma-70 factor family
BKM31_RS31505	COG0515	serine threonine protein kinase
BKM31_RS31505	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS31515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKM31_RS31540	COG2197	response regulator
BKM31_RS31550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKM31_RS31570	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKM31_RS31580	COG0477	Major facilitator Superfamily
BKM31_RS31595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKM31_RS31605	COG3226	Transcriptional regulator
BKM31_RS31620	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS31625	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS31635	COG2808	Putative FMN-binding domain
BKM31_RS31650	COG0444	Belongs to the ABC transporter superfamily
BKM31_RS31655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS31660	COG0601	transmembrane transport
BKM31_RS31705	COG1595	DNA-templated transcription, initiation
BKM31_RS31750	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS31770	COG5280	Phage tail tape measure protein TP901
BKM31_RS31770	COG3953	SLT domain
BKM31_RS31790	COG1674	ftsk spoiiie
BKM31_RS31835	COG1404	Belongs to the peptidase S8 family
BKM31_RS31850	COG0515	serine threonine protein kinase
BKM31_RS31895	COG1228	amidohydrolase
BKM31_RS31915	COG2814	Major facilitator Superfamily
BKM31_RS31940	COG1940	carbohydrate kinase activity
BKM31_RS31960	COG3119	arylsulfatase activity
BKM31_RS31980	COG1177	transmembrane transport
BKM31_RS31985	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKM31_RS31990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BKM31_RS31995	COG3842	ATPase activity
BKM31_RS32020	COG2132	Multicopper oxidase
BKM31_RS32030	COG4585	Histidine kinase
BKM31_RS32035	COG2197	response regulator
BKM31_RS32040	COG1376	ErfK ybiS ycfS ynhG family protein
BKM31_RS32050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKM31_RS32055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKM31_RS32070	COG0726	polysaccharide deacetylase
BKM31_RS32090	COG0789	Transcriptional regulator
BKM31_RS32100	COG0714	Associated with various cellular activities
BKM31_RS32105	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BKM31_RS32130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKM31_RS32135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKM31_RS32155	COG5564	TIM-barrel signal transduction protein
BKM31_RS32175	COG1953	Uracil, thiamine, allantoin
BKM31_RS32190	COG0667	Aldo Keto reductase
BKM31_RS32210	COG3119	arylsulfatase activity
BKM31_RS32220	COG1175	transmembrane transport
BKM31_RS32230	COG1609	Transcriptional regulator
BKM31_RS32235	COG2132	Multicopper oxidase
BKM31_RS32250	COG0531	amino acid
BKM31_RS32280	COG0395	ABC-type sugar transport system, permease component
BKM31_RS32285	COG1175	transmembrane transport
BKM31_RS32295	COG1940	carbohydrate kinase activity
BKM31_RS32305	COG3903	Transcriptional regulator
BKM31_RS32305	COG3629	intracellular signal transduction
BKM31_RS32325	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKM31_RS32405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKM31_RS32410	COG2814	Major facilitator Superfamily
BKM31_RS32435	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS32450	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
BKM31_RS32455	COG1396	sequence-specific DNA binding
BKM31_RS32460	COG3903	Transcriptional regulator
BKM31_RS32460	COG3629	intracellular signal transduction
BKM31_RS32490	COG0563	adenylate kinase activity
BKM31_RS32505	COG2319	Wd-40 repeat
BKM31_RS32505	COG4249	Peptidase C14 caspase catalytic subunit p20
BKM31_RS32540	COG3866	Pectate lyase
BKM31_RS32550	COG4221	oxidoreductase activity
BKM31_RS32570	COG2346	COG2346, Truncated hemoglobins
BKM31_RS32600	COG2201	protein-glutamate methylesterase activity
BKM31_RS32610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS32615	COG0574	Belongs to the PEP-utilizing enzyme family
BKM31_RS32615	COG3848	Pyruvate phosphate dikinase
BKM31_RS32635	COG2318	DinB family
BKM31_RS32650	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BKM31_RS32655	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BKM31_RS32670	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BKM31_RS32765	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BKM31_RS32800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKM31_RS32805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKM31_RS32810	COG0358	DNA primase activity
BKM31_RS32825	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BKM31_RS32830	COG0501	Belongs to the peptidase M48B family
BKM31_RS32845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKM31_RS32870	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKM31_RS32920	COG0574	Belongs to the PEP-utilizing enzyme family
BKM31_RS32920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKM31_RS32925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKM31_RS32935	COG0745	RESPONSE REGULATOR receiver
BKM31_RS32940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKM31_RS32945	COG2304	oxidoreductase activity
BKM31_RS32955	COG0714	Associated with various cellular activities
BKM31_RS32965	COG3547	Transposase (IS116 IS110 IS902 family)
BKM31_RS32970	COG0423	glycine-tRNA ligase activity
BKM31_RS32985	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS32990	COG3960	tartronate-semialdehyde synthase activity
BKM31_RS32995	COG2084	Dehydrogenase
BKM31_RS33000	COG3622	Belongs to the hyi family
BKM31_RS33010	COG0045	succinate-CoA ligase (ADP-forming) activity
BKM31_RS33020	COG1802	Transcriptional regulator
BKM31_RS33040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKM31_RS33040	COG0045	succinate-CoA ligase (ADP-forming) activity
BKM31_RS33040	COG1042	CoA-binding domain protein
BKM31_RS33045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKM31_RS33055	COG0303	'Molybdopterin
BKM31_RS33060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKM31_RS33065	COG3383	formate dehydrogenase (NAD+) activity
BKM31_RS33070	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BKM31_RS33080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKM31_RS33090	COG1121	(ABC) transporter
BKM31_RS33095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKM31_RS33115	COG2856	Zn peptidase
BKM31_RS33135	COG3559	Exporter of polyketide antibiotics
BKM31_RS33155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKM31_RS33160	COG1381	Involved in DNA repair and RecF pathway recombination
BKM31_RS33195	COG1834	amidinotransferase
BKM31_RS33200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKM31_RS33210	COG1595	DNA-templated transcription, initiation
BKM31_RS33225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKM31_RS33240	COG1309	transcriptional regulator
BKM31_RS33255	COG0531	amino acid
BKM31_RS33270	COG0673	inositol 2-dehydrogenase activity
BKM31_RS33305	COG0574	Belongs to the PEP-utilizing enzyme family
BKM31_RS33305	COG3848	Pyruvate phosphate dikinase
BKM31_RS33310	COG0477	Major facilitator Superfamily
BKM31_RS33320	COG2226	methyltransferase
BKM31_RS33325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKM31_RS33330	COG1834	amidinotransferase
BKM31_RS33340	COG0456	acetyltransferase
BKM31_RS33340	COG0454	-acetyltransferase
BKM31_RS33350	COG0477	Major facilitator Superfamily
BKM31_RS33355	COG0745	RESPONSE REGULATOR receiver
BKM31_RS33360	COG2205	protein histidine kinase activity
BKM31_RS33430	COG0831	urea catabolic process
BKM31_RS33435	COG0832	Belongs to the urease beta subunit family
BKM31_RS33440	COG0804	urea catabolic process
BKM31_RS33445	COG0830	nickel cation binding
BKM31_RS33450	COG0830	nickel cation binding
BKM31_RS33455	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BKM31_RS33460	COG0829	nickel cation binding
BKM31_RS33470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKM31_RS33495	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BKM31_RS33505	COG0537	adenosine 5'-monophosphoramidase activity
BKM31_RS33525	COG0484	heat shock protein binding
BKM31_RS33530	COG1420	regulation of RNA biosynthetic process
BKM31_RS33565	COG2258	MOSC domain
BKM31_RS33575	COG4585	Histidine kinase
BKM31_RS33590	COG3842	ATPase activity
BKM31_RS33610	COG0481	GTPase activity
BKM31_RS33620	COG0268	Binds directly to 16S ribosomal RNA
BKM31_RS33635	COG1136	(ABC) transporter
BKM31_RS33640	COG4591	ABC-type transport system involved in lipoprotein release permease component
BKM31_RS33640	COG1136	(ABC) transporter
BKM31_RS33665	COG1113	amino acid transport
BKM31_RS33670	COG2814	Major facilitator Superfamily
BKM31_RS33695	COG1555	photosystem II stabilization
BKM31_RS33695	COG1596	polysaccharide export
BKM31_RS33700	COG1307	EDD domain protein, DegV family
BKM31_RS33705	COG1228	amidohydrolase
BKM31_RS33710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKM31_RS33720	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BKM31_RS33725	COG0277	FAD linked oxidase domain protein
BKM31_RS33730	COG0277	FAD linked oxidase domain protein
BKM31_RS33735	COG0247	lactate metabolic process
BKM31_RS33740	COG1414	Transcriptional regulator
BKM31_RS33745	COG0745	RESPONSE REGULATOR receiver
BKM31_RS33755	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BKM31_RS33765	COG0793	Belongs to the peptidase S41A family
BKM31_RS33800	COG0745	RESPONSE REGULATOR receiver
BKM31_RS33865	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS33880	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BKM31_RS33885	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BKM31_RS33890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKM31_RS33895	COG1234	tRNA 3'-trailer cleavage
BKM31_RS33915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKM31_RS33920	COG1126	abc transporter atp-binding protein
BKM31_RS33925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKM31_RS33930	COG0765	amino acid transport
BKM31_RS33935	COG0765	amino acid transport
BKM31_RS33940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKM31_RS33945	COG1073	alpha beta
BKM31_RS33950	COG1418	mRNA catabolic process
BKM31_RS33960	COG2137	regulation of response to DNA damage stimulus
BKM31_RS33965	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKM31_RS33985	COG1201	RNA secondary structure unwinding
BKM31_RS33990	COG1309	transcriptional regulator
BKM31_RS34025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS34030	COG0444	Belongs to the ABC transporter superfamily
BKM31_RS34035	COG4608	Belongs to the ABC transporter superfamily
BKM31_RS34040	COG0405	Gamma-glutamyltransferase
BKM31_RS34050	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKM31_RS34075	COG0395	ABC-type sugar transport system, permease component
BKM31_RS34105	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKM31_RS34110	COG1396	sequence-specific DNA binding
BKM31_RS34115	COG1058	Belongs to the CinA family
BKM31_RS34115	COG1546	Belongs to the CinA family
BKM31_RS34125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKM31_RS34135	COG1674	ftsk spoiiie
BKM31_RS34140	COG3437	response regulator, receiver
BKM31_RS34165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM31_RS34170	COG1653	transport
BKM31_RS34175	COG1175	transmembrane transport
BKM31_RS34180	COG0395	ABC-type sugar transport system, permease component
BKM31_RS34205	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS34235	COG4585	Histidine kinase
BKM31_RS34240	COG1131	(ABC) transporter
BKM31_RS34260	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BKM31_RS34265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKM31_RS34290	COG2003	Belongs to the UPF0758 family
BKM31_RS34295	COG2188	Transcriptional regulator
BKM31_RS34300	COG2188	Transcriptional regulator
BKM31_RS34315	COG0697	spore germination
BKM31_RS34320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS34340	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKM31_RS34355	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKM31_RS34360	COG0612	Peptidase, M16
BKM31_RS34365	COG1185	polyribonucleotide nucleotidyltransferase activity
BKM31_RS34370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKM31_RS34380	COG1309	transcriptional regulator
BKM31_RS34400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BKM31_RS34405	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BKM31_RS34410	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BKM31_RS34420	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BKM31_RS34420	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BKM31_RS34430	COG0195	Participates in both transcription termination and antitermination
BKM31_RS34435	COG0779	Required for maturation of 30S ribosomal subunits
BKM31_RS34450	COG0442	prolyl-tRNA aminoacylation
BKM31_RS34460	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS34490	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS34495	COG0493	'glutamate synthase
BKM31_RS34510	COG1404	Belongs to the peptidase S8 family
BKM31_RS34525	COG1864	DNA RNA non-specific endonuclease
BKM31_RS34525	COG3591	Belongs to the peptidase S1B family
BKM31_RS34535	COG0028	Belongs to the TPP enzyme family
BKM31_RS34555	COG2188	Transcriptional regulator
BKM31_RS34575	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS34580	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS34655	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS34660	COG3540	Alkaline phosphatase
BKM31_RS34665	COG0183	Belongs to the thiolase family
BKM31_RS34670	COG1309	transcriptional regulator
BKM31_RS34690	COG1846	Transcriptional regulator
BKM31_RS34710	COG3173	Aminoglycoside phosphotransferase
BKM31_RS34715	COG0395	ABC-type sugar transport system, permease component
BKM31_RS34720	COG1175	transmembrane transport
BKM31_RS34725	COG1653	transport
BKM31_RS34730	COG4821	SIS domain
BKM31_RS34745	COG2188	Transcriptional regulator
BKM31_RS34750	COG0395	ABC-type sugar transport system, permease component
BKM31_RS34755	COG1175	transmembrane transport
BKM31_RS34760	COG2182	Extracellular solute-binding protein
BKM31_RS34765	COG5297	Belongs to the glycosyl hydrolase family 6
BKM31_RS34765	COG4447	cellulose binding
BKM31_RS34770	COG4821	SIS domain
BKM31_RS34775	COG1737	Transcriptional regulator
BKM31_RS34795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKM31_RS34805	COG0596	Alpha beta hydrolase
BKM31_RS34810	COG0583	DNA-binding transcription factor activity
BKM31_RS34825	COG3631	Ketosteroid isomerase-related protein
BKM31_RS34845	COG1595	DNA-templated transcription, initiation
BKM31_RS34860	COG3118	belongs to the thioredoxin family
BKM31_RS34860	COG0492	ferredoxin-NADP+ reductase activity
BKM31_RS34870	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BKM31_RS34885	COG0738	Major facilitator superfamily
BKM31_RS34890	COG3896	Chloramphenicol phosphotransferase-like protein
BKM31_RS34895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS34920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS34925	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS34935	COG0515	serine threonine protein kinase
BKM31_RS34945	COG0596	Alpha beta hydrolase
BKM31_RS34990	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS34995	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS35080	COG2409	Drug exporters of the RND superfamily
BKM31_RS35085	COG1309	transcriptional regulator
BKM31_RS35090	COG1940	carbohydrate kinase activity
BKM31_RS35120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM31_RS35170	COG0515	serine threonine protein kinase
BKM31_RS35170	COG2815	serine threonine protein kinase
BKM31_RS35185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS35220	COG0702	epimerase
BKM31_RS35245	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BKM31_RS35260	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS35275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKM31_RS35295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKM31_RS35305	COG0477	Major facilitator Superfamily
BKM31_RS35315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKM31_RS35330	COG0180	Tryptophanyl-tRNA synthetase
BKM31_RS35365	COG0628	permease
BKM31_RS35380	COG0577	efflux transmembrane transporter activity
BKM31_RS35385	COG0577	efflux transmembrane transporter activity
BKM31_RS35385	COG1136	(ABC) transporter
BKM31_RS35400	COG2205	protein histidine kinase activity
BKM31_RS35405	COG0745	RESPONSE REGULATOR receiver
BKM31_RS35410	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKM31_RS35435	COG3469	chitinase activity
BKM31_RS35450	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BKM31_RS35450	COG0778	Nitroreductase
BKM31_RS35480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS35485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS35510	COG4585	Histidine kinase
BKM31_RS35525	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS35550	COG0477	Major facilitator Superfamily
BKM31_RS35570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS35575	COG1177	transmembrane transport
BKM31_RS35580	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKM31_RS35590	COG3842	ATPase activity
BKM31_RS35595	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS35605	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BKM31_RS35625	COG0383	alpha-mannosidase activity
BKM31_RS35655	COG3718	enzyme involved in inositol metabolism
BKM31_RS35680	COG0456	acetyltransferase
BKM31_RS35695	COG4133	protoheme IX ABC transporter activity
BKM31_RS35705	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKM31_RS35715	COG0575	Belongs to the CDS family
BKM31_RS35720	COG0233	cytoplasmic translational termination
BKM31_RS35725	COG0528	UMP kinase activity
BKM31_RS35730	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKM31_RS35735	COG0052	Belongs to the universal ribosomal protein uS2 family
BKM31_RS35770	COG4974	Belongs to the 'phage' integrase family
BKM31_RS35785	COG0792	nuclease activity
BKM31_RS35795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKM31_RS35800	COG0681	Belongs to the peptidase S26 family
BKM31_RS35805	COG0681	Belongs to the peptidase S26 family
BKM31_RS35810	COG0335	large ribosomal subunit rRNA binding
BKM31_RS35815	COG0336	Belongs to the RNA methyltransferase TrmD family
BKM31_RS35820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BKM31_RS35825	COG1837	Belongs to the UPF0109 family
BKM31_RS35830	COG0228	four-way junction DNA binding
BKM31_RS35850	COG2018	Roadblock/LC7 domain
BKM31_RS35860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKM31_RS35870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKM31_RS35885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKM31_RS35890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKM31_RS35900	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS35915	COG2018	Roadblock/LC7 domain
BKM31_RS35920	COG5002	protein histidine kinase activity
BKM31_RS35925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKM31_RS35945	COG1116	anion transmembrane transporter activity
BKM31_RS35945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKM31_RS35995	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKM31_RS36010	COG2018	Roadblock/LC7 domain
BKM31_RS36015	COG5002	protein histidine kinase activity
BKM31_RS36020	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS36025	COG1819	glycosyl
BKM31_RS36035	COG3842	ATPase activity
BKM31_RS36040	COG1177	transmembrane transport
BKM31_RS36045	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKM31_RS36055	COG3281	Trehalose synthase
BKM31_RS36060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKM31_RS36075	COG2018	Roadblock/LC7 domain
BKM31_RS36085	COG0517	IMP dehydrogenase activity
BKM31_RS36085	COG4175	Glycine betaine
BKM31_RS36090	COG4176	ABC-type proline glycine betaine transport system permease component
BKM31_RS36145	COG2018	Roadblock/LC7 domain
BKM31_RS36150	COG5002	protein histidine kinase activity
BKM31_RS36155	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BKM31_RS36170	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BKM31_RS36185	COG1309	transcriptional regulator
BKM31_RS36195	COG1228	amidohydrolase
BKM31_RS36210	COG4221	oxidoreductase activity
BKM31_RS36230	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BKM31_RS36235	COG1132	(ABC) transporter
BKM31_RS36275	COG2186	Transcriptional regulator
BKM31_RS36295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKM31_RS36300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKM31_RS36305	COG0509	glycine decarboxylation via glycine cleavage system
BKM31_RS36310	COG1760	l-serine dehydratase
BKM31_RS36355	COG4585	Histidine kinase
BKM31_RS36360	COG2197	response regulator
BKM31_RS36365	COG1136	(ABC) transporter
BKM31_RS36365	COG0577	efflux transmembrane transporter activity
BKM31_RS36370	COG0577	efflux transmembrane transporter activity
BKM31_RS36390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKM31_RS36395	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BKM31_RS36405	COG1234	tRNA 3'-trailer cleavage
BKM31_RS36410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKM31_RS36450	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BKM31_RS36460	COG1335	isochorismatase
BKM31_RS36505	COG0477	Major facilitator Superfamily
BKM31_RS36510	COG1309	transcriptional regulator
BKM31_RS36515	COG1678	Uncharacterized ACR, COG1678
BKM31_RS36530	COG1414	Transcriptional regulator
BKM31_RS36535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKM31_RS36540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKM31_RS36555	COG1904	glucuronate isomerase
BKM31_RS36555	COG1102	Psort location Cytoplasmic, score
BKM31_RS36565	COG1846	Transcriptional regulator
BKM31_RS36630	COG0183	Belongs to the thiolase family
BKM31_RS36635	COG0346	lactoylglutathione lyase activity
BKM31_RS36645	COG0628	permease
BKM31_RS36650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKM31_RS36660	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS36685	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BKM31_RS36715	COG4585	Histidine kinase
BKM31_RS36720	COG1668	transmembrane transport
BKM31_RS36725	COG4152	abc transporter atp-binding protein
BKM31_RS36735	COG3328	transposase activity
BKM31_RS36755	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKM31_RS36760	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKM31_RS36765	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKM31_RS36770	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BKM31_RS36775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKM31_RS36780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKM31_RS36785	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKM31_RS36805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKM31_RS36810	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKM31_RS36830	COG2890	protein-(glutamine-N5) methyltransferase activity
BKM31_RS36835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKM31_RS36840	COG0254	rRNA binding
BKM31_RS36845	COG2197	response regulator
BKM31_RS36860	COG0083	homoserine kinase activity
BKM31_RS36865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKM31_RS36900	COG0463	Glycosyl transferase, family 2
BKM31_RS36905	COG0460	homoserine dehydrogenase
BKM31_RS36910	COG0019	diaminopimelate decarboxylase activity
BKM31_RS36940	COG0577	efflux transmembrane transporter activity
BKM31_RS36940	COG1136	(ABC) transporter
BKM31_RS36955	COG1653	transport
BKM31_RS36960	COG1175	transmembrane transport
BKM31_RS36965	COG0395	ABC-type sugar transport system, permease component
BKM31_RS36975	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BKM31_RS37000	COG4555	ABC transporter
BKM31_RS37035	COG1970	mechanosensitive ion channel activity
BKM31_RS37065	COG4585	Histidine kinase
BKM31_RS37070	COG2197	response regulator
BKM31_RS37075	COG0577	efflux transmembrane transporter activity
BKM31_RS37075	COG1136	(ABC) transporter
BKM31_RS37085	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS37090	COG0463	Glycosyl transferase, family 2
BKM31_RS37100	COG1063	alcohol dehydrogenase
BKM31_RS37105	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BKM31_RS37110	COG1082	Xylose isomerase domain protein TIM barrel
BKM31_RS37115	COG1063	alcohol dehydrogenase
BKM31_RS37130	COG1175	transmembrane transport
BKM31_RS37135	COG0395	ABC-type sugar transport system, permease component
BKM31_RS37165	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BKM31_RS37165	COG1703	isobutyryl-CoA mutase activity
BKM31_RS37165	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BKM31_RS37170	COG1063	alcohol dehydrogenase
BKM31_RS37185	COG2813	Specifically methylates the guanine in position
BKM31_RS37195	COG1653	transport
BKM31_RS37230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BKM31_RS37255	COG1175	transmembrane transport
BKM31_RS37315	COG0254	rRNA binding
BKM31_RS37320	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS37330	COG0514	ATP-dependent DNA helicase (RecQ)
BKM31_RS37360	COG2267	carboxylic ester hydrolase activity
BKM31_RS37365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKM31_RS37395	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKM31_RS37440	COG0596	Alpha beta hydrolase
BKM31_RS37445	COG0515	serine threonine protein kinase
BKM31_RS37455	COG1609	Transcriptional regulator
BKM31_RS37465	COG1175	transmembrane transport
BKM31_RS37470	COG0395	ABC-type sugar transport system, permease component
BKM31_RS37480	COG0672	)-iron permease
BKM31_RS37490	COG2837	iron assimilation
BKM31_RS37515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKM31_RS37540	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS37555	COG3842	ATPase activity
BKM31_RS37560	COG3842	ATPase activity
BKM31_RS37570	COG0395	ABC-type sugar transport system, permease component
BKM31_RS37590	COG0673	inositol 2-dehydrogenase activity
BKM31_RS37595	COG1653	transport
BKM31_RS37600	COG0395	ABC-type sugar transport system, permease component
BKM31_RS37605	COG1175	transmembrane transport
BKM31_RS37610	COG1609	Transcriptional regulator
BKM31_RS37615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKM31_RS37620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKM31_RS37625	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS37645	COG0601	transmembrane transport
BKM31_RS37655	COG4608	Belongs to the ABC transporter superfamily
BKM31_RS37660	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS37695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKM31_RS37720	COG0745	RESPONSE REGULATOR receiver
BKM31_RS37740	COG1174	glycine betaine transport
BKM31_RS37750	COG1174	glycine betaine transport
BKM31_RS37755	COG1732	Glycine betaine
BKM31_RS37760	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS37770	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BKM31_RS37785	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BKM31_RS37790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKM31_RS37795	COG0640	Transcriptional regulator
BKM31_RS37885	COG1819	glycosyl
BKM31_RS37895	COG1024	Enoyl-CoA hydratase
BKM31_RS37915	COG0515	serine threonine protein kinase
BKM31_RS37950	COG2755	lipolytic protein G-D-S-L family
BKM31_RS38030	COG0596	Alpha beta hydrolase
BKM31_RS38040	COG0640	Transcriptional regulator
BKM31_RS38055	COG1609	Transcriptional regulator
BKM31_RS38060	COG1233	COG1233 Phytoene dehydrogenase and related
BKM31_RS38075	COG0395	ABC-type sugar transport system, permease component
BKM31_RS38085	COG4977	sequence-specific DNA binding
BKM31_RS38110	COG4733	cellulase activity
BKM31_RS38110	COG5297	Belongs to the glycosyl hydrolase family 6
BKM31_RS38125	COG1733	regulation of RNA biosynthetic process
BKM31_RS38135	COG2235	arginine
BKM31_RS38145	COG1725	Transcriptional regulator
BKM31_RS38150	COG1131	(ABC) transporter
BKM31_RS38175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS38180	COG0431	NADPH-dependent FMN reductase
BKM31_RS38185	COG2207	Transcriptional regulator
BKM31_RS38190	COG2311	Membrane
BKM31_RS38200	COG3395	kinase activity
BKM31_RS38210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKM31_RS38225	COG2197	response regulator
BKM31_RS38230	COG1280	lysine exporter protein (LysE YggA)
BKM31_RS38235	COG1309	transcriptional regulator
BKM31_RS38255	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BKM31_RS38260	COG2205	protein histidine kinase activity
BKM31_RS38265	COG0745	RESPONSE REGULATOR receiver
BKM31_RS38300	COG0405	Gamma-glutamyltransferase
BKM31_RS38305	COG4585	Histidine kinase
BKM31_RS38310	COG2197	response regulator
BKM31_RS38330	COG0542	response to heat
BKM31_RS38345	COG0702	epimerase
BKM31_RS38375	COG0686	Belongs to the AlaDH PNT family
BKM31_RS38380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKM31_RS38420	COG0702	epimerase
BKM31_RS38455	COG0583	DNA-binding transcription factor activity
BKM31_RS38460	COG1280	lysine exporter protein (LysE YggA)
BKM31_RS38470	COG2197	response regulator
BKM31_RS38485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKM31_RS38515	COG2070	2-Nitropropane dioxygenase
BKM31_RS38530	COG4981	capsule polysaccharide biosynthetic process
BKM31_RS38535	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS38540	COG1215	transferase activity, transferring glycosyl groups
BKM31_RS38555	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS38570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKM31_RS38590	COG3903	Transcriptional regulator
BKM31_RS38590	COG3629	intracellular signal transduction
BKM31_RS38600	COG0515	serine threonine protein kinase
BKM31_RS38600	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS38605	COG4977	sequence-specific DNA binding
BKM31_RS38660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BKM31_RS38670	COG2884	Cell division ATP-binding protein ftsE
BKM31_RS38680	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKM31_RS38700	COG2902	Dehydrogenase
BKM31_RS38705	COG3483	tryptophan 2,3-dioxygenase activity
BKM31_RS38740	COG0277	FAD linked oxidase domain protein
BKM31_RS38760	COG1131	(ABC) transporter
BKM31_RS38770	COG2197	response regulator
BKM31_RS38775	COG3415	Transposase
BKM31_RS38775	COG2801	Transposase and inactivated derivatives
BKM31_RS38785	COG2207	Transcriptional regulator
BKM31_RS38795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKM31_RS38805	COG0583	DNA-binding transcription factor activity
BKM31_RS38820	COG0546	phosphoglycolate phosphatase activity
BKM31_RS38835	COG1011	Hydrolase
BKM31_RS38845	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS38850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKM31_RS38855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKM31_RS38855	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKM31_RS38865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKM31_RS38870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKM31_RS38875	COG2188	Transcriptional regulator
BKM31_RS38880	COG1263	PTS System
BKM31_RS38885	COG1263	PTS System
BKM31_RS38895	COG0653	protein targeting
BKM31_RS38905	COG3214	Protein conserved in bacteria
BKM31_RS38910	COG2197	response regulator
BKM31_RS38915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKM31_RS38930	COG5401	PFAM Sporulation and spore germination
BKM31_RS38935	COG5000	phosphorelay sensor kinase activity
BKM31_RS38935	COG5002	protein histidine kinase activity
BKM31_RS38960	COG0714	Associated with various cellular activities
BKM31_RS38995	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BKM31_RS39000	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BKM31_RS39015	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BKM31_RS39015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKM31_RS39030	COG2835	tetraacyldisaccharide 4'-kinase activity
BKM31_RS39035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKM31_RS39095	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BKM31_RS39100	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BKM31_RS39100	COG0778	Nitroreductase
BKM31_RS39115	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BKM31_RS39130	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS39140	COG2226	methyltransferase
BKM31_RS39150	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS39155	COG0463	Glycosyl transferase, family 2
BKM31_RS39175	COG1316	TRANSCRIPTIONal
BKM31_RS39180	COG3594	Acyltransferase
BKM31_RS39195	COG1595	DNA-templated transcription, initiation
BKM31_RS39205	COG1442	glycosyl transferase family 8
BKM31_RS39205	COG1216	Glycosyl transferase, family 2
BKM31_RS39215	COG0371	Dehydrogenase
BKM31_RS39220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BKM31_RS39235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BKM31_RS39250	COG1316	TRANSCRIPTIONal
BKM31_RS39255	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS39290	COG0346	lactoylglutathione lyase activity
BKM31_RS39320	COG1595	DNA-templated transcription, initiation
BKM31_RS39355	COG1396	sequence-specific DNA binding
BKM31_RS39365	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKM31_RS39375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKM31_RS39390	COG2205	protein histidine kinase activity
BKM31_RS39395	COG0745	RESPONSE REGULATOR receiver
BKM31_RS39405	COG2193	ferroxidase activity
BKM31_RS39415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKM31_RS39425	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKM31_RS39440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKM31_RS39445	COG0596	Alpha beta hydrolase
BKM31_RS39450	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BKM31_RS39460	COG1131	(ABC) transporter
BKM31_RS39465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKM31_RS39475	COG1432	Conserved Protein
BKM31_RS39500	COG2814	Major facilitator Superfamily
BKM31_RS39505	COG1846	Transcriptional regulator
BKM31_RS39665	COG1674	ftsk spoiiie
BKM31_RS39670	COG5280	Phage tail tape measure protein TP901
BKM31_RS39670	COG3953	SLT domain
BKM31_RS39675	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS39675	COG0515	serine threonine protein kinase
BKM31_RS39680	COG1404	Belongs to the peptidase S8 family
BKM31_RS39695	COG4770	biotin carboxylase activity
BKM31_RS39715	COG0477	Major facilitator Superfamily
BKM31_RS39780	COG1609	Transcriptional regulator
BKM31_RS39785	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS39790	COG1940	carbohydrate kinase activity
BKM31_RS39800	COG4209	transmembrane transport
BKM31_RS39805	COG0395	ABC-type sugar transport system, permease component
BKM31_RS39840	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS39870	COG1501	Belongs to the glycosyl hydrolase 31 family
BKM31_RS39895	COG0477	Major facilitator Superfamily
BKM31_RS39900	COG1522	sequence-specific DNA binding
BKM31_RS39905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKM31_RS39915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKM31_RS39945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKM31_RS39985	COG1079	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS39990	COG4603	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS39995	COG3845	ABC transporter
BKM31_RS40000	COG1744	ABC transporter substrate-binding protein PnrA-like
BKM31_RS40005	COG2936	dipeptidyl-peptidase activity
BKM31_RS40010	COG1473	amidohydrolase
BKM31_RS40010	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKM31_RS40025	COG1686	Belongs to the peptidase S11 family
BKM31_RS40035	COG0402	S-adenosylhomocysteine deaminase activity
BKM31_RS40070	COG4585	Histidine kinase
BKM31_RS40080	COG0180	Tryptophanyl-tRNA synthetase
BKM31_RS40085	COG1253	flavin adenine dinucleotide binding
BKM31_RS40095	COG0039	L-malate dehydrogenase activity
BKM31_RS40105	COG3268	Saccharopine dehydrogenase
BKM31_RS40115	COG0439	Biotin carboxylase
BKM31_RS40120	COG0538	isocitrate dehydrogenase activity
BKM31_RS40130	COG0372	Belongs to the citrate synthase family
BKM31_RS40140	COG1649	PFAM Uncharacterised BCR, COG1649
BKM31_RS40145	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS40150	COG1737	Transcriptional regulator
BKM31_RS40160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKM31_RS40170	COG0596	Alpha beta hydrolase
BKM31_RS40180	COG0138	bifunctional purine biosynthesis protein purh
BKM31_RS40205	COG0045	succinate-CoA ligase (ADP-forming) activity
BKM31_RS40265	COG0644	oxidoreductase
BKM31_RS40285	COG1487	ribonuclease activity
BKM31_RS40300	COG1376	ErfK ybiS ycfS ynhG family protein
BKM31_RS40305	COG2197	response regulator
BKM31_RS40345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKM31_RS40355	COG0457	Tetratricopeptide repeat
BKM31_RS40365	COG1216	Glycosyl transferase, family 2
BKM31_RS40375	COG2089	acid synthase
BKM31_RS40385	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BKM31_RS40390	COG1086	Polysaccharide biosynthesis protein
BKM31_RS40395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKM31_RS40400	COG1216	Glycosyl transferase, family 2
BKM31_RS40470	COG0784	Response regulator, receiver
BKM31_RS40475	COG4251	negative regulation of phosphorylation
BKM31_RS40480	COG0745	RESPONSE REGULATOR receiver
BKM31_RS40510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKM31_RS40510	COG0519	Catalyzes the synthesis of GMP from XMP
BKM31_RS40540	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS40565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKM31_RS40570	COG1349	DNA-binding transcription factor activity
BKM31_RS40580	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BKM31_RS40615	COG0516	GMP reductase activity
BKM31_RS40635	COG1595	DNA-templated transcription, initiation
BKM31_RS40645	COG0459	protein refolding
BKM31_RS40650	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKM31_RS40655	COG2890	protein-(glutamine-N5) methyltransferase activity
BKM31_RS40665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKM31_RS40675	COG1214	PFAM Peptidase M22, glycoprotease
BKM31_RS40675	COG0456	acetyltransferase
BKM31_RS40695	COG0802	atpase or kinase
BKM31_RS40705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKM31_RS40715	COG0736	holo-[acyl-carrier-protein] synthase activity
BKM31_RS40725	COG1072	(Pantothenic acid kinase))
BKM31_RS40735	COG1131	(ABC) transporter
BKM31_RS40765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKM31_RS40770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BKM31_RS40775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKM31_RS40795	COG0101	tRNA pseudouridine synthase activity
BKM31_RS40800	COG0203	ribosomal protein L17
BKM31_RS40805	COG0202	RNA polymerase activity
BKM31_RS40810	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKM31_RS40815	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKM31_RS40820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKM31_RS40825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BKM31_RS40830	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKM31_RS40850	COG0563	adenylate kinase activity
BKM31_RS40860	COG0200	Binds to the 23S rRNA
BKM31_RS40865	COG1841	ribosomal large subunit assembly
BKM31_RS40870	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKM31_RS40875	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BKM31_RS40880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKM31_RS40885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKM31_RS40890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKM31_RS40895	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKM31_RS40900	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BKM31_RS40905	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKM31_RS40910	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKM31_RS40915	COG0255	Belongs to the universal ribosomal protein uL29 family
BKM31_RS40920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKM31_RS40925	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKM31_RS40930	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BKM31_RS40935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BKM31_RS40940	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BKM31_RS40945	COG0089	rRNA binding
BKM31_RS40950	COG0088	Forms part of the polypeptide exit tunnel
BKM31_RS40955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKM31_RS40960	COG0051	transcription antitermination factor activity, RNA binding
BKM31_RS40970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKM31_RS40975	COG0049	tRNA binding
BKM31_RS40980	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKM31_RS40995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKM31_RS41000	COG0085	RNA polymerase activity
BKM31_RS41030	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKM31_RS41035	COG0222	ribosome binding
BKM31_RS41040	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKM31_RS41060	COG2130	NADP-dependent
BKM31_RS41070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKM31_RS41080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKM31_RS41090	COG0436	Aminotransferase
BKM31_RS41105	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKM31_RS41115	COG1595	DNA-templated transcription, initiation
BKM31_RS41125	COG0395	ABC-type sugar transport system, permease component
BKM31_RS41170	COG2814	Major facilitator Superfamily
BKM31_RS41180	COG0539	negative regulation of cytoplasmic translation
BKM31_RS41185	COG0183	Belongs to the thiolase family
BKM31_RS41215	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS41250	COG1573	uracil-dna glycosylase
BKM31_RS41270	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BKM31_RS41305	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS41310	COG1122	ATPase activity
BKM31_RS41315	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BKM31_RS41320	COG0310	cobalt ion transport
BKM31_RS41325	COG1215	transferase activity, transferring glycosyl groups
BKM31_RS41335	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKM31_RS41345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKM31_RS41365	COG2311	Membrane
BKM31_RS41395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKM31_RS41440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKM31_RS41445	COG1595	DNA-templated transcription, initiation
BKM31_RS41455	COG0215	cysteine-tRNA ligase activity
BKM31_RS41470	COG2261	transglycosylase associated protein
BKM31_RS41475	COG2261	transglycosylase associated protein
BKM31_RS41480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BKM31_RS41570	COG0596	Alpha beta hydrolase
BKM31_RS41590	COG0588	phosphoglycerate mutase activity
BKM31_RS41625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BKM31_RS41640	COG0501	Belongs to the peptidase M48B family
BKM31_RS41665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKM31_RS41685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS41700	COG1490	D-aminoacyl-tRNA deacylase activity
BKM31_RS41705	COG0354	folic acid binding
BKM31_RS41720	COG4044	May play a role in the intracellular transport of hydrophobic ligands
BKM31_RS41730	COG0640	Transcriptional regulator
BKM31_RS41740	COG3442	glutamine amidotransferase
BKM31_RS41745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKM31_RS41785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKM31_RS41830	COG0745	RESPONSE REGULATOR receiver
BKM31_RS41835	COG3629	intracellular signal transduction
BKM31_RS41835	COG3903	Transcriptional regulator
BKM31_RS41875	COG3842	ATPase activity
BKM31_RS41905	COG1674	ftsk spoiiie
BKM31_RS41915	COG0667	Aldo Keto reductase
BKM31_RS41920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS41935	COG3209	COG3209 Rhs family protein
BKM31_RS41995	COG3285	dna ligase
BKM31_RS41995	COG1793	dna ligase
BKM31_RS42010	COG0351	phosphomethylpyrimidine kinase
BKM31_RS42015	COG0352	thiamine-phosphate diphosphorylase activity
BKM31_RS42015	COG0351	phosphomethylpyrimidine kinase
BKM31_RS42015	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BKM31_RS42020	COG1966	Carbon starvation protein
BKM31_RS42030	COG2197	response regulator
BKM31_RS42035	COG4585	Histidine kinase
BKM31_RS42045	COG1280	lysine exporter protein (LysE YggA)
BKM31_RS42055	COG0528	UMP kinase activity
BKM31_RS42070	COG2267	carboxylic ester hydrolase activity
BKM31_RS42115	COG2226	methyltransferase
BKM31_RS42165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKM31_RS42165	COG0604	alcohol dehydrogenase
BKM31_RS42165	COG4221	oxidoreductase activity
BKM31_RS42165	COG3321	synthase
BKM31_RS42170	COG0657	acetylesterase activity
BKM31_RS42235	COG0717	Belongs to the dCTP deaminase family
BKM31_RS42240	COG1392	Phosphate transport regulator
BKM31_RS42245	COG0306	phosphate transporter
BKM31_RS42250	COG0456	acetyltransferase
BKM31_RS42250	COG0454	-acetyltransferase
BKM31_RS42255	COG0737	Belongs to the 5'-nucleotidase family
BKM31_RS42290	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BKM31_RS42295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKM31_RS42300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKM31_RS42305	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS42330	COG4585	Histidine kinase
BKM31_RS42335	COG2197	response regulator
BKM31_RS42355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS42360	COG0601	transmembrane transport
BKM31_RS42380	COG4221	oxidoreductase activity
BKM31_RS42390	COG0047	phosphoribosylformylglycinamidine synthase activity
BKM31_RS42405	COG0321	lipoyl(octanoyl) transferase activity
BKM31_RS42430	COG1968	undecaprenyl-diphosphatase activity
BKM31_RS42440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS42455	COG2814	Major facilitator Superfamily
BKM31_RS42460	COG0640	Transcriptional regulator
BKM31_RS42465	COG1643	Atp-dependent helicase
BKM31_RS42495	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS42505	COG1012	belongs to the aldehyde dehydrogenase family
BKM31_RS42515	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKM31_RS42515	COG1672	PFAM Archaeal ATPase
BKM31_RS42520	COG2119	membrane
BKM31_RS42525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BKM31_RS42540	COG2030	dehydratase
BKM31_RS42545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKM31_RS42580	COG0791	NLP P60 protein
BKM31_RS42605	COG0494	nUDIX hydrolase
BKM31_RS42610	COG2318	DinB family
BKM31_RS42625	COG3973	AAA domain
BKM31_RS42630	COG2226	methyltransferase
BKM31_RS42670	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BKM31_RS42705	COG4221	oxidoreductase activity
BKM31_RS42790	COG1609	Transcriptional regulator
BKM31_RS42815	COG1674	ftsk spoiiie
BKM31_RS42850	COG2188	Transcriptional regulator
BKM31_RS42930	COG1666	GTP binding
BKM31_RS42935	COG0494	nUDIX hydrolase
BKM31_RS42940	COG0501	Belongs to the peptidase M48B family
BKM31_RS42945	COG1007	ATP synthesis coupled electron transport
BKM31_RS42960	COG0713	ATP synthesis coupled electron transport
BKM31_RS42965	COG0839	Belongs to the complex I subunit 6 family
BKM31_RS42970	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM31_RS42990	COG0789	Transcriptional regulator
BKM31_RS42995	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS43005	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BKM31_RS43010	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM31_RS43015	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM31_RS43020	COG0501	Belongs to the peptidase M48B family
BKM31_RS43025	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM31_RS43030	COG0726	polysaccharide deacetylase
BKM31_RS43035	COG0674	pyruvate-flavodoxin oxidoreductase activity
BKM31_RS43035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BKM31_RS43040	COG1013	pyruvate-flavodoxin oxidoreductase activity
BKM31_RS43045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM31_RS43065	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKM31_RS43115	COG1215	transferase activity, transferring glycosyl groups
BKM31_RS43130	COG4310	Domain of unknown function (DUF2172)
BKM31_RS43145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKM31_RS43190	COG0697	spore germination
BKM31_RS43200	COG2755	lipolytic protein G-D-S-L family
BKM31_RS43200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKM31_RS43275	COG1595	DNA-templated transcription, initiation
BKM31_RS43300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKM31_RS43310	COG0142	geranyltranstransferase activity
BKM31_RS43325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKM31_RS43330	COG0713	ATP synthesis coupled electron transport
BKM31_RS43340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM31_RS43345	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BKM31_RS43350	COG1034	ATP synthesis coupled electron transport
BKM31_RS43355	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BKM31_RS43365	COG0649	NAD binding
BKM31_RS43370	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM31_RS43375	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM31_RS43400	COG2226	methyltransferase
BKM31_RS43435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKM31_RS43440	COG1333	cytochrome c biogenesis protein
BKM31_RS43445	COG0785	Cytochrome C biogenesis protein
BKM31_RS43450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKM31_RS43455	COG0406	alpha-ribazole phosphatase activity
BKM31_RS43460	COG0583	DNA-binding transcription factor activity
BKM31_RS43465	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKM31_RS43475	COG0113	porphobilinogen synthase activity
BKM31_RS43485	COG0181	hydroxymethylbilane synthase activity
BKM31_RS43490	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BKM31_RS43495	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BKM31_RS43510	COG1595	DNA-templated transcription, initiation
BKM31_RS43520	COG0560	Phosphoserine phosphatase
BKM31_RS43525	COG1316	TRANSCRIPTIONal
BKM31_RS43530	COG1595	DNA-templated transcription, initiation
BKM31_RS43535	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS43565	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKM31_RS43570	COG4585	Histidine kinase
BKM31_RS43575	COG2197	response regulator
BKM31_RS43590	COG0577	efflux transmembrane transporter activity
BKM31_RS43590	COG1136	(ABC) transporter
BKM31_RS43595	COG1136	(ABC) transporter
BKM31_RS43595	COG0577	efflux transmembrane transporter activity
BKM31_RS43605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKM31_RS43635	COG0443	Heat shock 70 kDa protein
BKM31_RS43640	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKM31_RS43645	COG0484	heat shock protein binding
BKM31_RS43650	COG0789	Transcriptional regulator
BKM31_RS43655	COG0542	response to heat
BKM31_RS43675	COG1309	transcriptional regulator
BKM31_RS43695	COG0477	Major facilitator Superfamily
BKM31_RS43700	COG0753	catalase activity
BKM31_RS43725	COG0243	molybdopterin cofactor binding
BKM31_RS43740	COG0702	epimerase
BKM31_RS43760	COG1119	ATPase activity
BKM31_RS43780	COG2197	response regulator
BKM31_RS43785	COG4585	Histidine kinase
BKM31_RS43790	COG4221	oxidoreductase activity
BKM31_RS43795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKM31_RS43805	COG3830	Belongs to the UPF0237 family
BKM31_RS43805	COG0560	Phosphoserine phosphatase
BKM31_RS43815	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BKM31_RS43825	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS43830	COG1111	helicase
BKM31_RS43830	COG1205	dead DEAH box helicase
BKM31_RS43835	COG1111	helicase
BKM31_RS43835	COG1205	dead DEAH box helicase
BKM31_RS43895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKM31_RS43910	COG0596	Alpha beta hydrolase
BKM31_RS43925	COG0667	Aldo Keto reductase
BKM31_RS43960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKM31_RS43980	COG0003	Pfam Anion-transporting ATPase
BKM31_RS43990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKM31_RS44000	COG1408	metallophosphoesterase
BKM31_RS44035	COG0515	serine threonine protein kinase
BKM31_RS44035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS44080	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS44110	COG0586	Pfam SNARE associated Golgi protein
BKM31_RS44120	COG1595	DNA-templated transcription, initiation
BKM31_RS44140	COG2378	regulation of single-species biofilm formation
BKM31_RS44150	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BKM31_RS44155	COG1802	Transcriptional regulator
BKM31_RS44175	COG3629	intracellular signal transduction
BKM31_RS44175	COG3903	Transcriptional regulator
BKM31_RS44195	COG3537	Alpha-1,2-mannosidase
BKM31_RS44220	COG0673	inositol 2-dehydrogenase activity
BKM31_RS44230	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BKM31_RS44240	COG0463	Glycosyl transferase, family 2
BKM31_RS44245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKM31_RS44275	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKM31_RS44280	COG2226	methyltransferase
BKM31_RS44295	COG0784	Response regulator, receiver
BKM31_RS44295	COG2205	protein histidine kinase activity
BKM31_RS44305	COG1432	Conserved Protein
BKM31_RS44320	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKM31_RS44345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKM31_RS44355	COG0584	glycerophosphoryl diester phosphodiesterase
BKM31_RS44365	COG0598	Magnesium transport protein CorA
BKM31_RS44370	COG0151	Belongs to the GarS family
BKM31_RS44375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKM31_RS44380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKM31_RS44395	COG0697	spore germination
BKM31_RS44415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKM31_RS44420	COG0515	serine threonine protein kinase
BKM31_RS44420	COG2815	serine threonine protein kinase
BKM31_RS44425	COG0583	DNA-binding transcription factor activity
BKM31_RS44430	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS44515	COG2018	Roadblock/LC7 domain
BKM31_RS44545	COG1846	Transcriptional regulator
BKM31_RS44550	COG0477	Major facilitator Superfamily
BKM31_RS44555	COG1070	Carbohydrate kinase
BKM31_RS44580	COG0431	NADPH-dependent FMN reductase
BKM31_RS44620	COG3619	membrane
BKM31_RS44635	COG0667	Aldo Keto reductase
BKM31_RS44660	COG1846	Transcriptional regulator
BKM31_RS44665	COG1595	DNA-templated transcription, initiation
BKM31_RS44685	COG1595	DNA-templated transcription, initiation
BKM31_RS44720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKM31_RS44735	COG2197	response regulator
BKM31_RS44795	COG1674	ftsk spoiiie
BKM31_RS44905	COG2319	Wd-40 repeat
BKM31_RS44905	COG4249	Peptidase C14 caspase catalytic subunit p20
BKM31_RS44920	COG3903	Transcriptional regulator
BKM31_RS44920	COG3629	intracellular signal transduction
BKM31_RS44930	COG4191	Histidine kinase
BKM31_RS44940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS45255	COG0604	alcohol dehydrogenase
BKM31_RS45265	COG0561	phosphatase activity
BKM31_RS45270	COG1278	Cold shock
BKM31_RS45280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKM31_RS45295	COG5650	phosphatidylinositol metabolic process
BKM31_RS45315	COG2318	DinB family
BKM31_RS45320	COG1215	transferase activity, transferring glycosyl groups
BKM31_RS45335	COG5002	protein histidine kinase activity
BKM31_RS45340	COG0745	RESPONSE REGULATOR receiver
BKM31_RS45365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKM31_RS45375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKM31_RS45380	COG1733	regulation of RNA biosynthetic process
BKM31_RS45390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKM31_RS45395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BKM31_RS45405	COG1316	TRANSCRIPTIONal
BKM31_RS45430	COG1716	ATPase activity
BKM31_RS45445	COG0768	penicillin binding
BKM31_RS45450	COG0515	serine threonine protein kinase
BKM31_RS45455	COG0515	serine threonine protein kinase
BKM31_RS45465	COG3764	Sortase (surface protein transpeptidase)
BKM31_RS45475	COG0705	Rhomboid family
BKM31_RS45500	COG0745	RESPONSE REGULATOR receiver
BKM31_RS45505	COG2205	protein histidine kinase activity
BKM31_RS45540	COG2072	flavoprotein involved in K transport
BKM31_RS45575	COG1309	transcriptional regulator
BKM31_RS45590	COG1522	sequence-specific DNA binding
BKM31_RS45595	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BKM31_RS45640	COG0745	RESPONSE REGULATOR receiver
BKM31_RS45645	COG5002	protein histidine kinase activity
BKM31_RS45655	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKM31_RS45660	COG1595	DNA-templated transcription, initiation
BKM31_RS45665	COG0456	acetyltransferase
BKM31_RS45680	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS45680	COG0515	serine threonine protein kinase
BKM31_RS45725	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BKM31_RS45730	COG0604	alcohol dehydrogenase
BKM31_RS45735	COG4221	oxidoreductase activity
BKM31_RS45800	COG1324	tolerance protein
BKM31_RS45815	COG1609	Transcriptional regulator
BKM31_RS45860	COG3852	Histidine kinase
BKM31_RS45880	COG2188	Transcriptional regulator
BKM31_RS45960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKM31_RS45970	COG2608	mercury ion transmembrane transporter activity
BKM31_RS45990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKM31_RS46010	COG0477	Major facilitator Superfamily
BKM31_RS46020	COG2837	iron assimilation
BKM31_RS46035	COG1510	regulation of RNA biosynthetic process
BKM31_RS46050	COG2409	Drug exporters of the RND superfamily
BKM31_RS46055	COG3903	Transcriptional regulator
BKM31_RS46055	COG3629	intracellular signal transduction
BKM31_RS46080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKM31_RS46085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKM31_RS46095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKM31_RS46100	COG2814	Major facilitator Superfamily
BKM31_RS46110	COG2175	clavaminate synthase activity
BKM31_RS46115	COG2177	Part of the ABC transporter FtsEX involved in
BKM31_RS46120	COG1136	(ABC) transporter
BKM31_RS46120	COG0577	efflux transmembrane transporter activity
BKM31_RS46130	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS46150	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS46160	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS46165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKM31_RS46170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKM31_RS46175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKM31_RS46180	COG0439	Biotin carboxylase
BKM31_RS46185	COG0511	ligase activity, forming carbon-carbon bonds
BKM31_RS46190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKM31_RS46190	COG0825	malonyl-CoA metabolic process
BKM31_RS46200	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS46210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKM31_RS46235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKM31_RS46240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKM31_RS46260	COG4585	Histidine kinase
BKM31_RS46265	COG2197	response regulator
BKM31_RS46290	COG3321	synthase
BKM31_RS46290	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS46290	COG0604	alcohol dehydrogenase
BKM31_RS46295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKM31_RS46300	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS46305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM31_RS46310	COG0596	Alpha beta hydrolase
BKM31_RS46330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKM31_RS46340	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
BKM31_RS46345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKM31_RS46350	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BKM31_RS46355	COG0592	DNA-directed DNA polymerase activity
BKM31_RS46360	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKM31_RS46365	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BKM31_RS46370	COG0594	ribonuclease P activity
BKM31_RS46375	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BKM31_RS46380	COG0706	membrane insertase activity
BKM31_RS46390	COG0357	Ribosomal RNA small subunit methyltransferase G
BKM31_RS46395	COG1192	Involved in chromosome partitioning
BKM31_RS46415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS46425	COG3118	belongs to the thioredoxin family
BKM31_RS46430	COG0492	ferredoxin-NADP+ reductase activity
BKM31_RS46440	COG1595	DNA-templated transcription, initiation
BKM31_RS46445	COG2815	serine threonine protein kinase
BKM31_RS46445	COG0515	serine threonine protein kinase
BKM31_RS46465	COG0617	tRNA 3'-terminal CCA addition
BKM31_RS46475	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BKM31_RS46520	COG0360	Binds together with S18 to 16S ribosomal RNA
BKM31_RS46525	COG0629	single-stranded DNA binding
BKM31_RS46530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKM31_RS46535	COG0359	binds to the 23S rRNA
BKM31_RS46545	COG0765	amino acid transport
BKM31_RS46550	COG1126	abc transporter atp-binding protein
BKM31_RS46555	COG0531	amino acid
BKM31_RS46565	COG0305	Participates in initiation and elongation during chromosome replication
BKM31_RS46585	COG0577	efflux transmembrane transporter activity
BKM31_RS46585	COG1136	(ABC) transporter
BKM31_RS46605	COG3386	PFAM SMP-30 Gluconolaconase
BKM31_RS46615	COG1131	(ABC) transporter
BKM31_RS46625	COG2197	response regulator
BKM31_RS46630	COG0592	DNA-directed DNA polymerase activity
BKM31_RS46650	COG2186	Transcriptional regulator
BKM31_RS46670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BKM31_RS46685	COG0590	tRNA wobble adenosine to inosine editing
BKM31_RS46740	COG3284	Transcriptional regulator
BKM31_RS46745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKM31_RS46750	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKM31_RS46775	COG1309	transcriptional regulator
BKM31_RS46820	COG1309	transcriptional regulator
BKM31_RS46825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKM31_RS46835	COG2890	protein-(glutamine-N5) methyltransferase activity
BKM31_RS46840	COG3629	intracellular signal transduction
BKM31_RS46840	COG3903	Transcriptional regulator
BKM31_RS46850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKM31_RS46855	COG0583	DNA-binding transcription factor activity
BKM31_RS46860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKM31_RS46880	COG1316	TRANSCRIPTIONal
BKM31_RS46885	COG2226	methyltransferase
BKM31_RS46890	COG2271	Major facilitator Superfamily
BKM31_RS46910	COG1595	DNA-templated transcription, initiation
BKM31_RS46935	COG0583	DNA-binding transcription factor activity
BKM31_RS46940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKM31_RS46950	COG1846	Transcriptional regulator
BKM31_RS46955	COG0488	(ABC) transporter
BKM31_RS46980	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
BKM31_RS47020	COG1316	TRANSCRIPTIONal
BKM31_RS47035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKM31_RS47040	COG2197	response regulator
BKM31_RS47045	COG4585	Histidine kinase
BKM31_RS47055	COG2132	Multicopper oxidase
BKM31_RS47090	COG0477	Major facilitator Superfamily
BKM31_RS47120	COG2274	protein secretion by the type I secretion system
BKM31_RS47130	COG0596	Alpha beta hydrolase
BKM31_RS47185	COG1754	DNA topoisomerase type I activity
BKM31_RS47185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKM31_RS47190	COG1408	metallophosphoesterase
BKM31_RS47200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BKM31_RS47205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKM31_RS47220	COG1774	PSP1 C-terminal conserved region
BKM31_RS47260	COG2186	Transcriptional regulator
BKM31_RS47265	COG1653	transport
BKM31_RS47270	COG1175	transmembrane transport
BKM31_RS47275	COG0395	ABC-type sugar transport system, permease component
BKM31_RS47285	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS47305	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS47320	COG0488	(ABC) transporter
BKM31_RS47340	COG3883	PFAM NLP P60 protein
BKM31_RS47340	COG0791	NLP P60 protein
BKM31_RS47345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BKM31_RS47360	COG0037	tRNA processing
BKM31_RS47375	COG0302	gtp cyclohydrolase
BKM31_RS47380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKM31_RS47390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BKM31_RS47415	COG0649	NAD binding
BKM31_RS47425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKM31_RS47430	COG0861	Integral membrane protein TerC family
BKM31_RS47455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKM31_RS47465	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BKM31_RS47470	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BKM31_RS47480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKM31_RS47485	COG2130	NADP-dependent
BKM31_RS47490	COG1733	regulation of RNA biosynthetic process
BKM31_RS47515	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BKM31_RS47535	COG0542	response to heat
BKM31_RS47595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BKM31_RS47600	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BKM31_RS47605	COG3118	belongs to the thioredoxin family
BKM31_RS47615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKM31_RS47620	COG1082	Xylose isomerase domain protein TIM barrel
BKM31_RS47625	COG2264	protein methyltransferase activity
BKM31_RS47635	COG2181	nitrate reductase activity
BKM31_RS47635	COG0247	lactate metabolic process
BKM31_RS47645	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS47650	COG1937	Protein conserved in bacteria
BKM31_RS47710	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
BKM31_RS47750	COG0515	serine threonine protein kinase
BKM31_RS47755	COG0693	protein deglycase activity
BKM31_RS47780	COG0791	NLP P60 protein
BKM31_RS47780	COG0741	lytic transglycosylase activity
BKM31_RS47795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKM31_RS47800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKM31_RS47805	COG0142	geranyltranstransferase activity
BKM31_RS47815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BKM31_RS47855	COG5297	Belongs to the glycosyl hydrolase family 6
BKM31_RS47860	COG4733	cellulase activity
BKM31_RS47860	COG5297	Belongs to the glycosyl hydrolase family 6
BKM31_RS47880	COG5297	Belongs to the glycosyl hydrolase family 6
BKM31_RS47895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKM31_RS47910	COG1846	Transcriptional regulator
BKM31_RS47920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKM31_RS47945	COG2201	protein-glutamate methylesterase activity
BKM31_RS47950	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS47955	COG4264	IucA IucC family
BKM31_RS47970	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BKM31_RS47970	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKM31_RS47990	COG1595	DNA-templated transcription, initiation
BKM31_RS48005	COG2197	response regulator
BKM31_RS48010	COG4585	Histidine kinase
BKM31_RS48020	COG1131	(ABC) transporter
BKM31_RS48030	COG1309	transcriptional regulator
BKM31_RS48035	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS48040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS48055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKM31_RS48070	COG1649	PFAM Uncharacterised BCR, COG1649
BKM31_RS48085	COG2211	Major facilitator Superfamily
BKM31_RS48090	COG1309	transcriptional regulator
BKM31_RS48125	COG0577	efflux transmembrane transporter activity
BKM31_RS48130	COG1136	(ABC) transporter
BKM31_RS48165	COG3835	regulator
BKM31_RS48195	COG2192	nodulation
BKM31_RS48205	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKM31_RS48230	COG3903	Transcriptional regulator
BKM31_RS48230	COG3629	intracellular signal transduction
BKM31_RS48250	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BKM31_RS48260	COG3250	beta-galactosidase activity
BKM31_RS48265	COG0395	ABC-type sugar transport system, permease component
BKM31_RS48270	COG1175	transmembrane transport
BKM31_RS48280	COG1609	Transcriptional regulator
BKM31_RS48300	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKM31_RS48305	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS48350	COG2124	cytochrome p450
BKM31_RS48385	COG2205	protein histidine kinase activity
BKM31_RS48390	COG0745	RESPONSE REGULATOR receiver
BKM31_RS48435	COG1605	Chorismate mutase
BKM31_RS48435	COG0287	Prephenate dehydrogenase
BKM31_RS48450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS48465	COG2197	response regulator
BKM31_RS48470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKM31_RS48485	COG0584	glycerophosphoryl diester phosphodiesterase
BKM31_RS48500	COG2814	Major facilitator Superfamily
BKM31_RS48505	COG1959	2 iron, 2 sulfur cluster binding
BKM31_RS48550	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS48590	COG0667	Aldo Keto reductase
BKM31_RS48600	COG4946	Tricorn protease homolog
BKM31_RS48600	COG0823	Involved in the tonB-independent uptake of proteins
BKM31_RS48600	COG1506	peptidase
BKM31_RS48645	COG2188	Transcriptional regulator
BKM31_RS48650	COG0133	tryptophan synthase activity
BKM31_RS48655	COG0159	tryptophan synthase activity
BKM31_RS48675	COG4585	Histidine kinase
BKM31_RS48685	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BKM31_RS48715	COG1278	Cold shock
BKM31_RS48750	COG1175	transmembrane transport
BKM31_RS48800	COG1278	Cold shock
BKM31_RS48805	COG0513	Belongs to the DEAD box helicase family
BKM31_RS48815	COG4974	Belongs to the 'phage' integrase family
BKM31_RS48825	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS48910	COG2197	response regulator
BKM31_RS48915	COG0167	dihydroorotate dehydrogenase activity
BKM31_RS48920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKM31_RS48940	COG1609	Transcriptional regulator
BKM31_RS48945	COG1309	transcriptional regulator
BKM31_RS48970	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKM31_RS48980	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS49005	COG1132	(ABC) transporter
BKM31_RS49015	COG1309	transcriptional regulator
BKM31_RS49030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKM31_RS49030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKM31_RS49045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKM31_RS49050	COG0047	phosphoribosylformylglycinamidine synthase activity
BKM31_RS49060	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKM31_RS49070	COG0022	dehydrogenase e1 component
BKM31_RS49075	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKM31_RS49095	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS49105	COG2076	Multidrug Resistance protein
BKM31_RS49125	COG0243	molybdopterin cofactor binding
BKM31_RS49135	COG0667	Aldo Keto reductase
BKM31_RS49165	COG0384	phenazine biosynthesis protein PhzF
BKM31_RS49170	COG1799	cell septum assembly
BKM31_RS49180	COG0018	arginyl-trna synthetase
BKM31_RS49185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKM31_RS49190	COG0416	fatty acid biosynthetic process
BKM31_RS49200	COG1509	lysine 2,3-aminomutase activity
BKM31_RS49210	COG1134	teichoic acid transport
BKM31_RS49220	COG0747	negative chemotaxis
BKM31_RS49230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS49240	COG4608	Belongs to the ABC transporter superfamily
BKM31_RS49265	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
BKM31_RS49295	COG1595	DNA-templated transcription, initiation
BKM31_RS49305	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BKM31_RS49315	COG0459	protein refolding
BKM31_RS49325	COG1881	PFAM PEBP family protein
BKM31_RS49330	COG3973	AAA domain
BKM31_RS49340	COG1061	Type III restriction enzyme res subunit
BKM31_RS49350	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS49370	COG1309	transcriptional regulator
BKM31_RS49385	COG1278	Cold shock
BKM31_RS49390	COG2814	Major facilitator Superfamily
BKM31_RS49410	COG2211	Major facilitator Superfamily
BKM31_RS49420	COG2252	PERMEase
BKM31_RS49435	COG0667	Aldo Keto reductase
BKM31_RS49455	COG0579	oxidoreductase
BKM31_RS49460	COG0745	RESPONSE REGULATOR receiver
BKM31_RS49465	COG2205	protein histidine kinase activity
BKM31_RS49470	COG0745	RESPONSE REGULATOR receiver
BKM31_RS49480	COG1160	GTP binding
BKM31_RS49490	COG0583	DNA-binding transcription factor activity
BKM31_RS49495	COG0156	8-amino-7-oxononanoate synthase activity
BKM31_RS49500	COG1063	alcohol dehydrogenase
BKM31_RS49505	COG1940	carbohydrate kinase activity
BKM31_RS49510	COG0673	inositol 2-dehydrogenase activity
BKM31_RS49540	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKM31_RS49565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS49565	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BKM31_RS49580	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS49585	COG2409	Drug exporters of the RND superfamily
BKM31_RS49595	COG1819	glycosyl
BKM31_RS49605	COG1653	transport
BKM31_RS49610	COG0395	ABC-type sugar transport system, permease component
BKM31_RS49615	COG1175	transmembrane transport
BKM31_RS49620	COG1846	Transcriptional regulator
BKM31_RS49620	COG1940	carbohydrate kinase activity
BKM31_RS49635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKM31_RS49660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKM31_RS49670	COG0667	Aldo Keto reductase
BKM31_RS49675	COG0583	DNA-binding transcription factor activity
BKM31_RS49710	COG0737	Belongs to the 5'-nucleotidase family
BKM31_RS49720	COG1271	oxidase subunit
BKM31_RS49725	COG2197	response regulator
BKM31_RS49730	COG4585	Histidine kinase
BKM31_RS49755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS49790	COG1609	Transcriptional regulator
BKM31_RS49800	COG4585	Histidine kinase
BKM31_RS49815	COG0395	ABC-type sugar transport system, permease component
BKM31_RS49820	COG1175	transmembrane transport
BKM31_RS49845	COG2080	2 iron, 2 sulfur cluster binding
BKM31_RS49850	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKM31_RS49855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKM31_RS49915	COG1846	Transcriptional regulator
BKM31_RS49990	COG1131	(ABC) transporter
BKM31_RS50000	COG1595	DNA-templated transcription, initiation
BKM31_RS50005	COG1132	(ABC) transporter
BKM31_RS50010	COG1132	(ABC) transporter
BKM31_RS50035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS50040	COG0542	response to heat
BKM31_RS50060	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKM31_RS50090	COG3467	pyridoxamine 5'-phosphate
BKM31_RS50145	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKM31_RS50175	COG1609	Transcriptional regulator
BKM31_RS50180	COG1175	transmembrane transport
BKM31_RS50185	COG0395	ABC-type sugar transport system, permease component
BKM31_RS50200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKM31_RS50210	COG1725	Transcriptional regulator
BKM31_RS50215	COG1131	(ABC) transporter
BKM31_RS50230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKM31_RS50235	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS50240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKM31_RS50245	COG0714	Associated with various cellular activities
BKM31_RS50260	COG2304	oxidoreductase activity
BKM31_RS50270	COG2318	DinB family
BKM31_RS50275	COG1597	lipid kinase activity
BKM31_RS50280	COG3537	Alpha-1,2-mannosidase
BKM31_RS50290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKM31_RS50335	COG0667	Aldo Keto reductase
BKM31_RS50350	COG0515	serine threonine protein kinase
BKM31_RS50350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS50365	COG2226	methyltransferase
BKM31_RS50385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKM31_RS50385	COG3320	Male sterility
BKM31_RS50405	COG0789	Transcriptional regulator
BKM31_RS50410	COG0667	Aldo Keto reductase
BKM31_RS50500	COG2080	2 iron, 2 sulfur cluster binding
BKM31_RS50505	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKM31_RS50510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKM31_RS50530	COG1846	Transcriptional regulator
BKM31_RS50600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS50605	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS50625	COG0210	DNA helicase
BKM31_RS50650	COG1609	Transcriptional regulator
BKM31_RS50715	COG1397	ADP-ribosylglycohydrolase
BKM31_RS50740	COG1876	peptidase activity
BKM31_RS50745	COG1970	mechanosensitive ion channel activity
BKM31_RS50755	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BKM31_RS50760	COG0477	Major facilitator Superfamily
BKM31_RS50775	COG3263	regulation of cellular component size
BKM31_RS50780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BKM31_RS50785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKM31_RS50795	COG0315	cyclic pyranopterin monophosphate synthase activity
BKM31_RS50800	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKM31_RS50805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKM31_RS50820	COG1396	sequence-specific DNA binding
BKM31_RS50845	COG0604	alcohol dehydrogenase
BKM31_RS50850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKM31_RS50865	COG3135	benzoate transporter
BKM31_RS50870	COG0346	lactoylglutathione lyase activity
BKM31_RS50880	COG0577	efflux transmembrane transporter activity
BKM31_RS50880	COG1136	(ABC) transporter
BKM31_RS50940	COG3401	FG-GAP repeat protein
BKM31_RS50950	COG2124	cytochrome p450
BKM31_RS50960	COG0583	DNA-binding transcription factor activity
BKM31_RS50965	COG0251	oxidation-reduction process
BKM31_RS51000	COG2267	carboxylic ester hydrolase activity
BKM31_RS51005	COG1522	sequence-specific DNA binding
BKM31_RS51015	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS51025	COG0477	Major facilitator Superfamily
BKM31_RS51060	COG4941	Belongs to the sigma-70 factor family
BKM31_RS51065	COG1660	Displays ATPase and GTPase activities
BKM31_RS51070	COG0789	Transcriptional regulator
BKM31_RS51085	COG0789	Transcriptional regulator
BKM31_RS51120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKM31_RS51125	COG0084	hydrolase, TatD family'
BKM31_RS51130	COG3583	domain protein
BKM31_RS51145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKM31_RS51160	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKM31_RS51165	COG0488	(ABC) transporter
BKM31_RS51170	COG1846	Transcriptional regulator
BKM31_RS51175	COG4106	trans-aconitate 2-methyltransferase activity
BKM31_RS51195	COG0406	alpha-ribazole phosphatase activity
BKM31_RS51195	COG0494	nUDIX hydrolase
BKM31_RS51200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BKM31_RS51220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKM31_RS51225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKM31_RS51230	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BKM31_RS51235	COG0193	aminoacyl-tRNA hydrolase activity
BKM31_RS51245	COG1218	3'(2'),5'-bisphosphate nucleotidase
BKM31_RS51250	COG0175	sulfate reduction
BKM31_RS51310	COG0730	response to heat
BKM31_RS51315	COG0529	Catalyzes the synthesis of activated sulfate
BKM31_RS51350	COG0148	phosphopyruvate hydratase activity
BKM31_RS51385	COG1573	uracil-dna glycosylase
BKM31_RS51390	COG1252	NADH dehydrogenase
BKM31_RS51395	COG3830	Belongs to the UPF0237 family
BKM31_RS51400	COG0242	peptide deformylase activity
BKM31_RS51420	COG3467	pyridoxamine 5'-phosphate
BKM31_RS51425	COG0183	Belongs to the thiolase family
BKM31_RS51435	COG2755	lipolytic protein G-D-S-L family
BKM31_RS51515	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BKM31_RS51540	COG0308	aminopeptidase N
BKM31_RS51545	COG1714	RDD family
BKM31_RS51550	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BKM31_RS51555	COG1522	sequence-specific DNA binding
BKM31_RS51560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKM31_RS51565	COG1331	Highly conserved protein containing a thioredoxin domain
BKM31_RS51585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKM31_RS51595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKM31_RS51610	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BKM31_RS51620	COG3220	belongs to the UPF0276 family
BKM31_RS51640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKM31_RS51645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BKM31_RS51655	COG2205	protein histidine kinase activity
BKM31_RS51660	COG0745	RESPONSE REGULATOR receiver
BKM31_RS51695	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS51700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKM31_RS51705	COG0114	fumarate hydratase activity
BKM31_RS51715	COG0515	serine threonine protein kinase
BKM31_RS51725	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BKM31_RS51725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BKM31_RS51735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS51740	COG0673	inositol 2-dehydrogenase activity
BKM31_RS51760	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS51790	COG1722	exodeoxyribonuclease VII activity
BKM31_RS51805	COG1570	exodeoxyribonuclease VII activity
BKM31_RS51815	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKM31_RS51870	COG0791	NLP P60 protein
BKM31_RS51875	COG0494	nUDIX hydrolase
BKM31_RS51910	COG0784	Response regulator, receiver
BKM31_RS51915	COG4251	negative regulation of phosphorylation
BKM31_RS51935	COG1053	succinate dehydrogenase
BKM31_RS51940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKM31_RS51980	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKM31_RS51985	COG1136	(ABC) transporter
BKM31_RS52030	COG2814	Major facilitator Superfamily
BKM31_RS52045	COG1690	Belongs to the RtcB family
BKM31_RS52060	COG0494	nUDIX hydrolase
BKM31_RS52070	COG1595	DNA-templated transcription, initiation
BKM31_RS52115	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS52140	COG1140	nitrate reductase beta subunit
BKM31_RS52155	COG1132	(ABC) transporter
BKM31_RS52160	COG1132	(ABC) transporter
BKM31_RS52170	COG1280	lysine exporter protein (LysE YggA)
BKM31_RS52175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKM31_RS52190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKM31_RS52225	COG0215	cysteine-tRNA ligase activity
BKM31_RS52245	COG4106	trans-aconitate 2-methyltransferase activity
BKM31_RS52280	COG2171	N-acyltransferase activity
BKM31_RS52285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKM31_RS52290	COG1611	Belongs to the LOG family
BKM31_RS52295	COG1611	Belongs to the LOG family
BKM31_RS52305	COG2818	Glycosylase
BKM31_RS52310	COG5492	domain, Protein
BKM31_RS52325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKM31_RS52335	COG1595	DNA-templated transcription, initiation
BKM31_RS52345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKM31_RS52350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKM31_RS52355	COG2151	metal-sulfur cluster biosynthetic enzyme
BKM31_RS52355	COG0489	protein tyrosine kinase activity
BKM31_RS52370	COG2239	Acts as a magnesium transporter
BKM31_RS52440	COG0513	Belongs to the DEAD box helicase family
BKM31_RS52465	COG3285	dna ligase
BKM31_RS52465	COG1793	dna ligase
BKM31_RS52470	COG1793	dna ligase
BKM31_RS52470	COG3285	dna ligase
BKM31_RS52475	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKM31_RS52500	COG0596	Alpha beta hydrolase
BKM31_RS52515	COG1404	Belongs to the peptidase S8 family
BKM31_RS52525	COG1404	Belongs to the peptidase S8 family
BKM31_RS52540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKM31_RS52565	COG0019	diaminopimelate decarboxylase activity
BKM31_RS52605	COG1946	Acyl-CoA thioesterase
BKM31_RS52635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKM31_RS52685	COG3480	Lon protease (S16) C-terminal proteolytic domain
BKM31_RS52690	COG1615	UPF0182 protein
BKM31_RS52745	COG2154	pterin-4-alpha-carbinolamine dehydratase
BKM31_RS52760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKM31_RS52780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKM31_RS52800	COG0483	inositol monophosphate 1-phosphatase activity
BKM31_RS52820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKM31_RS52830	COG2135	peptidase activity
BKM31_RS52845	COG1595	DNA-templated transcription, initiation
BKM31_RS52850	COG5662	AntiSigma factor
BKM31_RS52855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM31_RS52860	COG2199	diguanylate cyclase activity
BKM31_RS52860	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BKM31_RS52875	COG0515	serine threonine protein kinase
BKM31_RS52890	COG2197	response regulator
BKM31_RS52900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BKM31_RS52905	COG2188	Transcriptional regulator
BKM31_RS52910	COG0156	8-amino-7-oxononanoate synthase activity
BKM31_RS52925	COG1597	lipid kinase activity
BKM31_RS52940	COG2172	sigma factor antagonist activity
BKM31_RS52965	COG0765	amino acid transport
BKM31_RS53015	COG3293	Transposase
BKM31_RS53065	COG0604	alcohol dehydrogenase
BKM31_RS53090	COG0567	Dehydrogenase, E1 component
BKM31_RS53090	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKM31_RS53110	COG0435	Glutathione S-transferase
BKM31_RS53120	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS53125	COG1940	carbohydrate kinase activity
BKM31_RS53125	COG1846	Transcriptional regulator
BKM31_RS53130	COG1129	ABC transporter
BKM31_RS53135	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS53175	COG0604	alcohol dehydrogenase
BKM31_RS53175	COG3321	synthase
BKM31_RS53200	COG0438	transferase activity, transferring glycosyl groups
BKM31_RS53220	COG2124	cytochrome p450
BKM31_RS53225	COG2318	DinB family
BKM31_RS53230	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKM31_RS53235	COG4948	Mandelate Racemase Muconate Lactonizing
BKM31_RS53255	COG1129	ABC transporter
BKM31_RS53260	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS53280	COG2186	Transcriptional regulator
BKM31_RS53290	COG0183	Belongs to the thiolase family
BKM31_RS53300	COG0640	Transcriptional regulator
BKM31_RS53315	COG1309	transcriptional regulator
BKM31_RS53320	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS53325	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS53330	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS53350	COG1595	DNA-templated transcription, initiation
BKM31_RS53365	COG1174	glycine betaine transport
BKM31_RS53370	COG1174	glycine betaine transport
BKM31_RS53390	COG0616	signal peptide processing
BKM31_RS53410	COG4585	Histidine kinase
BKM31_RS53415	COG1404	Belongs to the peptidase S8 family
BKM31_RS53420	COG1404	Belongs to the peptidase S8 family
BKM31_RS53425	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BKM31_RS53435	COG2084	Dehydrogenase
BKM31_RS53440	COG3281	Trehalose synthase
BKM31_RS53450	COG0366	Alpha amylase catalytic
BKM31_RS53455	COG0058	SHG alpha-glucan phosphorylase activity
BKM31_RS53460	COG1737	Transcriptional regulator
BKM31_RS53470	COG1132	(ABC) transporter
BKM31_RS53475	COG1132	(ABC) transporter
BKM31_RS53505	COG3622	Belongs to the hyi family
BKM31_RS53510	COG2084	Dehydrogenase
BKM31_RS53535	COG0425	Belongs to the sulfur carrier protein TusA family
BKM31_RS53535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKM31_RS53575	COG2362	D-Aminopeptidase
BKM31_RS53590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS53590	COG0515	serine threonine protein kinase
BKM31_RS53595	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKM31_RS53595	COG0515	serine threonine protein kinase
BKM31_RS53610	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BKM31_RS53640	COG4221	oxidoreductase activity
BKM31_RS53650	COG2205	protein histidine kinase activity
BKM31_RS53655	COG0745	RESPONSE REGULATOR receiver
BKM31_RS53675	COG0738	Major facilitator superfamily
BKM31_RS53695	COG0482	sulfurtransferase activity
BKM31_RS53700	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKM31_RS53710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKM31_RS53725	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKM31_RS53730	COG0154	amidase activity
BKM31_RS53735	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKM31_RS53750	COG3181	Tripartite tricarboxylate transporter family receptor
BKM31_RS53755	COG3290	protein histidine kinase activity
BKM31_RS53760	COG4565	transcriptional regulatory protein
BKM31_RS53770	COG2133	pyrroloquinoline quinone binding
BKM31_RS53775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKM31_RS53790	COG0440	acetolactate synthase activity
BKM31_RS53795	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKM31_RS53800	COG0604	alcohol dehydrogenase
BKM31_RS53800	COG3321	synthase
BKM31_RS53800	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS53825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKM31_RS53830	COG3835	regulator
BKM31_RS53865	COG2340	Cysteine-rich secretory protein family
BKM31_RS53870	COG2027	D-alanyl-D-alanine carboxypeptidase
BKM31_RS53885	COG1136	(ABC) transporter
BKM31_RS53885	COG0577	efflux transmembrane transporter activity
BKM31_RS53895	COG2211	Major facilitator Superfamily
BKM31_RS53905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKM31_RS53915	COG0791	NLP P60 protein
BKM31_RS53925	COG0473	3-isopropylmalate dehydrogenase activity
BKM31_RS53930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKM31_RS53940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKM31_RS53985	COG1302	Protein conserved in bacteria
BKM31_RS53990	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKM31_RS53995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKM31_RS54000	COG0534	Mate efflux family protein
BKM31_RS54010	COG1090	epimerase
BKM31_RS54015	COG0339	signal peptide processing
BKM31_RS54030	COG4585	Histidine kinase
BKM31_RS54035	COG2197	response regulator
BKM31_RS54060	COG1414	Transcriptional regulator
BKM31_RS54065	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKM31_RS54070	COG0066	3-isopropylmalate dehydratase activity
BKM31_RS54080	COG0776	regulation of translation
BKM31_RS54095	COG1920	GTP binding
BKM31_RS54105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKM31_RS54110	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKM31_RS54135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKM31_RS54140	COG1461	Dihydroxyacetone kinase
BKM31_RS54150	COG0742	ribosomal rna small subunit methyltransferase
BKM31_RS54155	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKM31_RS54165	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BKM31_RS54170	COG0571	ribonuclease III activity
BKM31_RS54175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKM31_RS54190	COG1254	Belongs to the acylphosphatase family
BKM31_RS54220	COG0667	Aldo Keto reductase
BKM31_RS54230	COG1090	epimerase
BKM31_RS54250	COG1120	ATPase activity
BKM31_RS54255	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKM31_RS54260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKM31_RS54270	COG1595	DNA-templated transcription, initiation
BKM31_RS54285	COG0726	polysaccharide deacetylase
BKM31_RS54295	COG1217	gtp-binding protein TYPA
BKM31_RS54335	COG2723	6-phospho-beta-galactosidase activity
BKM31_RS54345	COG0667	Aldo Keto reductase
BKM31_RS54350	COG0789	Transcriptional regulator
BKM31_RS54355	COG0768	penicillin binding
BKM31_RS54360	COG2274	protein secretion by the type I secretion system
BKM31_RS54380	COG1175	transmembrane transport
BKM31_RS54385	COG0395	ABC-type sugar transport system, permease component
BKM31_RS54390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKM31_RS54395	COG0406	alpha-ribazole phosphatase activity
BKM31_RS54410	COG4214	carbohydrate transport
BKM31_RS54420	COG4213	ABC transporter substrate-binding protein
BKM31_RS54445	COG2807	transmembrane transport
BKM31_RS54465	COG1609	Transcriptional regulator
BKM31_RS54470	COG2986	histidine ammonia-lyase
BKM31_RS54475	COG1950	PFAM Membrane protein of
BKM31_RS54515	COG0745	RESPONSE REGULATOR receiver
BKM31_RS54530	COG1136	(ABC) transporter
BKM31_RS54530	COG0577	efflux transmembrane transporter activity
BKM31_RS54535	COG0577	efflux transmembrane transporter activity
BKM31_RS54535	COG1136	(ABC) transporter
BKM31_RS54540	COG2205	protein histidine kinase activity
BKM31_RS54545	COG1132	(ABC) transporter
BKM31_RS54575	COG2124	cytochrome p450
BKM31_RS54580	COG2124	cytochrome p450
BKM31_RS54590	COG3424	synthase
BKM31_RS54595	COG1024	Enoyl-CoA hydratase
BKM31_RS54600	COG1024	Enoyl-CoA hydratase
BKM31_RS54605	COG1024	Enoyl-CoA hydratase
BKM31_RS54615	COG0475	glutathione-regulated potassium exporter activity
BKM31_RS54635	COG2197	response regulator
BKM31_RS54655	COG2186	Transcriptional regulator
BKM31_RS54660	COG0747	negative chemotaxis
BKM31_RS54670	COG0444	Belongs to the ABC transporter superfamily
BKM31_RS54675	COG4608	Belongs to the ABC transporter superfamily
BKM31_RS54680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKM31_RS54690	COG0753	catalase activity
BKM31_RS54725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKM31_RS54730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKM31_RS54750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKM31_RS54765	COG3959	Transketolase, thiamine diphosphate binding domain
BKM31_RS54770	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS54845	COG0653	protein targeting
BKM31_RS54860	COG2815	serine threonine protein kinase
BKM31_RS54860	COG0515	serine threonine protein kinase
BKM31_RS54870	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS54875	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS54880	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS54885	COG1309	transcriptional regulator
BKM31_RS54965	COG2205	protein histidine kinase activity
BKM31_RS54970	COG0745	RESPONSE REGULATOR receiver
BKM31_RS54985	COG1136	(ABC) transporter
BKM31_RS54985	COG0577	efflux transmembrane transporter activity
BKM31_RS54990	COG0577	efflux transmembrane transporter activity
BKM31_RS55010	COG2323	membrane
BKM31_RS55035	COG2267	carboxylic ester hydrolase activity
BKM31_RS55060	COG1733	regulation of RNA biosynthetic process
BKM31_RS55080	COG0235	Class ii aldolase
BKM31_RS55085	COG3226	Transcriptional regulator
BKM31_RS55100	COG1051	belongs to the nudix hydrolase family
BKM31_RS55120	COG1653	transport
BKM31_RS55130	COG0395	ABC-type sugar transport system, permease component
BKM31_RS55135	COG2154	pterin-4-alpha-carbinolamine dehydratase
BKM31_RS55170	COG0768	penicillin binding
BKM31_RS55210	COG4585	Histidine kinase
BKM31_RS55245	COG2197	response regulator
BKM31_RS55255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BKM31_RS55300	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS55325	COG2311	Membrane
BKM31_RS55345	COG1649	PFAM Uncharacterised BCR, COG1649
BKM31_RS55345	COG0726	polysaccharide deacetylase
BKM31_RS55355	COG0463	Glycosyl transferase, family 2
BKM31_RS55405	COG1609	Transcriptional regulator
BKM31_RS55425	COG3422	double-strand break repair
BKM31_RS55435	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKM31_RS55450	COG3629	intracellular signal transduction
BKM31_RS55480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS55500	COG0667	Aldo Keto reductase
BKM31_RS55505	COG0789	Transcriptional regulator
BKM31_RS55535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKM31_RS55545	COG0129	dihydroxy-acid dehydratase activity
BKM31_RS55560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKM31_RS55585	COG1764	response to oxidative stress
BKM31_RS55595	COG0698	ribose 5-phosphate isomerase
BKM31_RS55610	COG0747	negative chemotaxis
BKM31_RS55615	COG0601	transmembrane transport
BKM31_RS55620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS55630	COG4608	Belongs to the ABC transporter superfamily
BKM31_RS55670	COG2814	Major facilitator Superfamily
BKM31_RS55680	COG1260	myo-inositol-1-phosphate synthase
BKM31_RS55695	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BKM31_RS55715	COG4974	Belongs to the 'phage' integrase family
BKM31_RS55750	COG3903	Transcriptional regulator
BKM31_RS55750	COG3629	intracellular signal transduction
BKM31_RS55795	COG2801	Transposase and inactivated derivatives
BKM31_RS55875	COG1757	Na H antiporter
BKM31_RS55895	COG4249	Peptidase C14 caspase catalytic subunit p20
BKM31_RS55895	COG2319	Wd-40 repeat
BKM31_RS55930	COG1396	sequence-specific DNA binding
BKM31_RS55935	COG0740	serine-type endopeptidase activity
BKM31_RS55940	COG0740	serine-type endopeptidase activity
BKM31_RS55945	COG2382	esterase
BKM31_RS55945	COG3693	PFAM glycoside hydrolase, family 10
BKM31_RS55950	COG3509	depolymerase
BKM31_RS55960	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKM31_RS55965	COG1716	ATPase activity
BKM31_RS55990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKM31_RS56000	COG1077	Cell shape determining protein MreB Mrl
BKM31_RS56015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKM31_RS56025	COG1940	carbohydrate kinase activity
BKM31_RS56030	COG2211	Major facilitator Superfamily
BKM31_RS56055	COG1082	Xylose isomerase domain protein TIM barrel
BKM31_RS56060	COG3959	Transketolase, thiamine diphosphate binding domain
BKM31_RS56065	COG3958	Transketolase
BKM31_RS56070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKM31_RS56080	COG1129	ABC transporter
BKM31_RS56085	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS56105	COG0604	alcohol dehydrogenase
BKM31_RS56120	COG0583	DNA-binding transcription factor activity
BKM31_RS56135	COG2197	response regulator
BKM31_RS56140	COG4585	Histidine kinase
BKM31_RS56180	COG2186	Transcriptional regulator
BKM31_RS56205	COG1278	Cold shock
BKM31_RS56210	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKM31_RS56215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BKM31_RS56220	COG1794	racemase activity, acting on amino acids and derivatives
BKM31_RS56225	COG1686	Belongs to the peptidase S11 family
BKM31_RS56255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKM31_RS56265	COG0789	Transcriptional regulator
BKM31_RS56275	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BKM31_RS56280	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BKM31_RS56285	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BKM31_RS56325	COG0574	Belongs to the PEP-utilizing enzyme family
BKM31_RS56325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKM31_RS56345	COG1937	Protein conserved in bacteria
BKM31_RS56350	COG2608	mercury ion transmembrane transporter activity
BKM31_RS56405	COG0596	Alpha beta hydrolase
BKM31_RS56410	COG4585	Histidine kinase
BKM31_RS56415	COG2197	response regulator
BKM31_RS56425	COG1132	(ABC) transporter
BKM31_RS56450	COG0477	Major facilitator Superfamily
BKM31_RS56460	COG3831	ATPase activity
BKM31_RS56465	COG0714	Associated with various cellular activities
BKM31_RS56470	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BKM31_RS56475	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BKM31_RS56490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKM31_RS56500	COG1982	Orn Lys Arg decarboxylase major
BKM31_RS56505	COG0248	Ppx GppA phosphatase
BKM31_RS56510	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKM31_RS56515	COG3848	Pyruvate phosphate dikinase
BKM31_RS56515	COG0574	Belongs to the PEP-utilizing enzyme family
BKM31_RS56520	COG1940	carbohydrate kinase activity
BKM31_RS56535	COG0395	ABC-type sugar transport system, permease component
BKM31_RS56555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKM31_RS56575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKM31_RS56585	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKM31_RS56605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKM31_RS56615	COG1940	carbohydrate kinase activity
BKM31_RS56630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM31_RS56650	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BKM31_RS56660	COG2197	response regulator
BKM31_RS56675	COG3629	intracellular signal transduction
BKM31_RS56675	COG3903	Transcriptional regulator
BKM31_RS56680	COG3629	intracellular signal transduction
BKM31_RS56680	COG3903	Transcriptional regulator
BKM31_RS56695	COG0488	(ABC) transporter
BKM31_RS56700	COG0488	(ABC) transporter
BKM31_RS56710	COG2072	flavoprotein involved in K transport
BKM31_RS56715	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKM31_RS56730	COG3629	intracellular signal transduction
BKM31_RS56730	COG3903	Transcriptional regulator
BKM31_RS56745	COG1132	(ABC) transporter
BKM31_RS56760	COG0702	epimerase
BKM31_RS56825	COG1959	2 iron, 2 sulfur cluster binding
BKM31_RS56855	COG1609	Transcriptional regulator
BKM31_RS56895	COG1175	transmembrane transport
BKM31_RS56905	COG1609	Transcriptional regulator
BKM31_RS56920	COG2205	protein histidine kinase activity
BKM31_RS56935	COG1366	Belongs to the anti-sigma-factor antagonist family
BKM31_RS56955	COG1309	transcriptional regulator
BKM31_RS56960	COG0789	Transcriptional regulator
BKM31_RS56965	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS56970	COG0789	Transcriptional regulator
BKM31_RS56990	COG1492	cobalamin metabolic process
BKM31_RS56995	COG2271	Major facilitator Superfamily
BKM31_RS57005	COG1131	(ABC) transporter
BKM31_RS57025	COG1280	lysine exporter protein (LysE YggA)
BKM31_RS57035	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKM31_RS57045	COG4257	antibiotic catabolic process
BKM31_RS57050	COG0488	(ABC) transporter
BKM31_RS57080	COG3842	ATPase activity
BKM31_RS57095	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BKM31_RS57100	COG2188	Transcriptional regulator
BKM31_RS57110	COG0587	DNA-directed DNA polymerase activity
BKM31_RS57120	COG2197	response regulator
BKM31_RS57125	COG1136	(ABC) transporter
BKM31_RS57135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS57145	COG2186	Transcriptional regulator
BKM31_RS57150	COG0247	lactate metabolic process
BKM31_RS57155	COG1139	Iron-sulfur cluster binding protein
BKM31_RS57160	COG1556	Lactate utilization protein
BKM31_RS57190	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BKM31_RS57200	COG1648	precorrin-2 dehydrogenase activity
BKM31_RS57200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKM31_RS57295	COG1960	acyl-CoA dehydrogenase activity
BKM31_RS57300	COG1309	transcriptional regulator
BKM31_RS57305	COG2030	dehydratase
BKM31_RS57310	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS57315	COG0477	Major facilitator Superfamily
BKM31_RS57320	COG0824	Thioesterase
BKM31_RS57330	COG0366	Alpha amylase catalytic
BKM31_RS57340	COG0668	transmembrane transport
BKM31_RS57390	COG0494	nUDIX hydrolase
BKM31_RS57430	COG1505	serine-type exopeptidase activity
BKM31_RS57460	COG0129	dihydroxy-acid dehydratase activity
BKM31_RS57490	COG0515	serine threonine protein kinase
BKM31_RS57500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BKM31_RS57510	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS57515	COG0242	peptide deformylase activity
BKM31_RS57520	COG0698	ribose 5-phosphate isomerase
BKM31_RS57525	COG4552	Acetyltransferase involved in intracellular survival and related
BKM31_RS57535	COG2197	response regulator
BKM31_RS57540	COG0750	zinc metalloprotease
BKM31_RS57545	COG2205	protein histidine kinase activity
BKM31_RS57550	COG0745	RESPONSE REGULATOR receiver
BKM31_RS57590	COG1349	DNA-binding transcription factor activity
BKM31_RS57595	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BKM31_RS57650	COG2318	DinB family
BKM31_RS57665	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKM31_RS57670	COG0740	serine-type endopeptidase activity
BKM31_RS57675	COG0740	serine-type endopeptidase activity
BKM31_RS57680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKM31_RS57685	COG0525	valine-tRNA ligase activity
BKM31_RS57710	COG0285	dihydrofolate synthase activity
BKM31_RS57725	COG0105	UTP biosynthetic process
BKM31_RS57730	COG1077	Cell shape determining protein MreB Mrl
BKM31_RS57735	COG1792	Involved in formation and maintenance of cell shape
BKM31_RS57750	COG0772	Belongs to the SEDS family
BKM31_RS57770	COG1530	ribonuclease E activity
BKM31_RS57775	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKM31_RS57780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKM31_RS57785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKM31_RS57795	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BKM31_RS57800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKM31_RS57810	COG0501	Belongs to the peptidase M48B family
BKM31_RS57815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BKM31_RS57820	COG0799	negative regulation of ribosome biogenesis
BKM31_RS57825	COG0406	alpha-ribazole phosphatase activity
BKM31_RS57845	COG1215	transferase activity, transferring glycosyl groups
BKM31_RS57865	COG2378	regulation of single-species biofilm formation
BKM31_RS57890	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKM31_RS57890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BKM31_RS57910	COG2205	protein histidine kinase activity
BKM31_RS57915	COG0745	RESPONSE REGULATOR receiver
BKM31_RS57960	COG2807	transmembrane transport
BKM31_RS57970	COG1595	DNA-templated transcription, initiation
BKM31_RS58000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS58005	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BKM31_RS58015	COG1609	Transcriptional regulator
BKM31_RS58020	COG1879	ABC-type sugar transport system periplasmic component
BKM31_RS58030	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS58035	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKM31_RS58040	COG4213	ABC transporter substrate-binding protein
BKM31_RS58050	COG4214	carbohydrate transport
BKM31_RS58055	COG1609	Transcriptional regulator
BKM31_RS58070	COG2160	L-arabinose isomerase activity
BKM31_RS58080	COG0277	FAD linked oxidase domain protein
BKM31_RS58125	COG1755	Isoprenylcysteine carboxyl methyltransferase
BKM31_RS58195	COG4977	sequence-specific DNA binding
BKM31_RS58220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKM31_RS58230	COG0424	maF-like protein
BKM31_RS58245	COG1595	DNA-templated transcription, initiation
BKM31_RS58275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKM31_RS58280	COG1793	dna ligase
BKM31_RS58290	COG1028	Short-chain dehydrogenase reductase Sdr
BKM31_RS58315	COG2124	cytochrome p450
BKM31_RS58320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKM31_RS58325	COG2815	serine threonine protein kinase
BKM31_RS58325	COG0515	serine threonine protein kinase
BKM31_RS58330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKM31_RS58340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKM31_RS58345	COG3509	depolymerase
BKM31_RS58370	COG0318	PFAM AMP-dependent synthetase and ligase
BKM31_RS58385	COG0596	Alpha beta hydrolase
BKM31_RS58410	COG0495	leucyl-tRNA aminoacylation
BKM31_RS58415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKM31_RS58425	COG4946	Tricorn protease homolog
BKM31_RS58425	COG0793	Belongs to the peptidase S41A family
BKM31_RS58450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKM31_RS58465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKM31_RS58470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKM31_RS58495	COG0584	glycerophosphoryl diester phosphodiesterase
BKM31_RS58525	COG0477	Major facilitator Superfamily
BKM31_RS58540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKM31_RS58590	COG0596	Alpha beta hydrolase
BKM31_RS58600	COG0477	Major facilitator Superfamily
BKM31_RS58630	COG1984	allophanate hydrolase subunit 2
BKM31_RS58635	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKM31_RS58640	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKM31_RS58660	COG5001	Diguanylate cyclase
BKM31_RS58665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKM31_RS58670	COG3022	response to hydroperoxide
BKM31_RS58685	COG0187	DNA topoisomerase II activity
BKM31_RS58715	COG1472	Belongs to the glycosyl hydrolase 3 family
BKM31_RS58720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKM31_RS58725	COG2175	clavaminate synthase activity
BKM31_RS58730	COG0514	ATP-dependent DNA helicase (RecQ)
BKM31_RS58735	COG2815	serine threonine protein kinase
BKM31_RS58735	COG0515	serine threonine protein kinase
BKM31_RS58800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKM31_RS58805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKM31_RS58810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKM31_RS58825	COG3766	membrane
BKM31_RS58830	COG0754	glutathionylspermidine amidase activity
BKM31_RS58845	COG2378	regulation of single-species biofilm formation
BKM31_RS58860	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BKM31_RS58870	COG0432	Pfam Uncharacterised protein family UPF0047
BKM31_RS58890	COG1940	carbohydrate kinase activity
BKM31_RS58900	COG4585	Histidine kinase
BKM31_RS58905	COG2197	response regulator
BKM31_RS58975	COG0667	Aldo Keto reductase
BKM31_RS58985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKM31_RS58995	COG0456	acetyltransferase
BKM31_RS59005	COG2223	nitrite transmembrane transporter activity
BKM31_RS59010	COG0243	molybdopterin cofactor binding
BKM31_RS59015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKM31_RS59020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKM31_RS59020	COG2146	nitrite reductase [NAD(P)H] activity
BKM31_RS59060	COG2186	Transcriptional regulator
BKM31_RS59070	COG2936	dipeptidyl-peptidase activity
BKM31_RS59080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKM31_RS59110	COG0477	Major facilitator Superfamily