locus-tag class description FD724_RS00005 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) FD724_RS00015 ENOG4105F32 YngK protein FD724_RS00045 ENOG4107WDG serine threonine protein kinase FD724_RS00080 ENOG4108428 Inherit from COG: -acetyltransferase FD724_RS00090 ENOG4105BZU Histidine kinase FD724_RS00100 ENOG4105BZU Histidine kinase FD724_RS00115 ENOG4107U7Q Transfers the fatty acyl group on membrane lipoproteins (By similarity) FD724_RS00130 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FD724_RS00155 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FD724_RS00165 ENOG4108IXY short-chain dehydrogenase reductase FD724_RS00170 ENOG4107P5I polyketide synthase FD724_RS00175 ENOG4107QKG PfaD family FD724_RS00190 ENOG4108JA1 polyketide synthase FD724_RS00210 ENOG4105K64 Glycosyl transferase, family 2 FD724_RS00230 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase FD724_RS00260 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase FD724_RS00265 ENOG4105E4C Lytic transglycosylase catalytic FD724_RS00270 ENOG4108R6K riboflavin synthase, subunit alpha FD724_RS00280 ENOG4105CPC Aldo Keto reductase FD724_RS00305 ENOG4105CPK Glycosyl transferase (Group 1 FD724_RS00325 ENOG4106855 Competence protein FD724_RS00345 ENOG4108VAU general secretion pathway protein G FD724_RS00370 ENOG4107Y1F Involved in the transcription termination process (By similarity) FD724_RS00380 ENOG4107SGM protein serine threonine phosphatase FD724_RS00410 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FD724_RS00415 ENOG4105VPX protein, conserved in bacteria FD724_RS00430 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FD724_RS00440 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) FD724_RS00455 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) FD724_RS00465 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) FD724_RS00485 ENOG4105D9P serine threonine protein kinase FD724_RS00525 ENOG4108ISE 4Fe-4S ferredoxin, iron-sulfur binding FD724_RS00540 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FD724_RS00565 ENOG4105CZX twitching motility protein FD724_RS00570 ENOG4107QHF type ii secretion system protein e FD724_RS00580 ENOG4105CFG Acts as a chaperone (By similarity) FD724_RS00585 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FD724_RS00595 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FD724_RS00605 ENOG4107RFW hydrolase family 57 FD724_RS00610 ENOG4105D1D Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FD724_RS00615 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FD724_RS00625 ENOG4108Z7R Chaperone CsaA FD724_RS00640 ENOG4105E1F short-chain dehydrogenase reductase FD724_RS00720 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FD724_RS00725 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FD724_RS00760 ENOG4105Y3U Transglycosylase-associated protein FD724_RS00765 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FD724_RS00770 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FD724_RS00775 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) FD724_RS00795 ENOG4105CJN penicillin-binding protein FD724_RS00810 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FD724_RS00825 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FD724_RS00845 ENOG4108KHP Diguanylate cyclase FD724_RS00855 ENOG4107TVC Glycosyl transferase, family 2 FD724_RS00875 ENOG4105EIE fructose-bisphosphate aldolase FD724_RS00915 ENOG4108S64 thioredoxin-like protein txlA FD724_RS00930 ENOG4105BZU Histidine kinase FD724_RS00935 ENOG4105BZU Histidine kinase FD724_RS00945 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase FD724_RS00950 ENOG4105FUA antagonist FD724_RS00955 ENOG4107MMM Anti-sigma-factor antagonist FD724_RS00980 ENOG4105C02 permease FD724_RS01040 ENOG4108V3E phosphoribosylglycinamide formyltransferase FD724_RS01085 ENOG4105KVH Transcriptional regulator FD724_RS01105 ENOG4105GVF (ABC) transporter FD724_RS01110 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FD724_RS01125 ENOG41068BY Low temperature-induced protein FD724_RS01130 ENOG4108RMU ferritin dps family protein FD724_RS01185 ENOG41063FQ CsbD-like protein FD724_RS01200 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FD724_RS01235 ENOG4105VFU Rna-binding protein FD724_RS01240 ENOG410848W 30S ribosomal protein S21 FD724_RS01250 ENOG4107QIB glycyl-tRNA synthetase, alpha subunit FD724_RS01290 ENOG41066AK Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity) FD724_RS01310 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS01315 ENOG4105BZU Histidine kinase FD724_RS01320 ENOG4105BZU Histidine kinase FD724_RS01330 ENOG41082SX arsR family transcriptional regulator FD724_RS01340 ENOG41082AN stage II sporulation protein FD724_RS01345 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS01360 ENOG4105BZU Histidine kinase FD724_RS01375 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS01410 ENOG4105CQR helicase FD724_RS01420 ENOG41080W8 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) FD724_RS01435 ENOG4107U45 Cobalt transport protein FD724_RS01440 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FD724_RS01450 ENOG4106INZ Photosystem I reaction center subunit FD724_RS01455 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase FD724_RS01460 ENOG4105EUJ GTP cyclohydrolase i FD724_RS01470 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) FD724_RS01480 ENOG410612X Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane FD724_RS01485 ENOG4105DRS transport system, permease FD724_RS01515 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FD724_RS01520 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FD724_RS01540 ENOG4108K9Q Controls heterocyst differentiation. Has both a protease and a DNA-binding activity (By similarity) FD724_RS01565 ENOG4105CJ3 phosphate transporter FD724_RS01575 ENOG4105CPQ Dehydrogenase FD724_RS01580 ENOG4107TCE N-acetyltransferase FD724_RS01635 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FD724_RS01665 ENOG4105CPC Aldo Keto reductase FD724_RS01670 ENOG4105GVF (ABC) transporter FD724_RS01675 ENOG4105BZ1 (ABC) transporter FD724_RS01685 ENOG4105GVF (ABC) transporter FD724_RS01725 ENOG4107WDG serine threonine protein kinase FD724_RS01735 ENOG4105D5K Hemolysin activator protein FD724_RS01755 ENOG4108HMN Caspase domain FD724_RS01775 ENOG4105RRH FD724_RS01780 ENOG410715G filament integrity protein FD724_RS01790 ENOG4106D5S Corrinoid adenosyltransferase BtuR CobO CobP FD724_RS01795 ENOG4105ESV Glycosyl transferase, family 4 FD724_RS01800 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) FD724_RS01805 ENOG4105D7N magnesium and cobalt transport protein CorA FD724_RS01820 ENOG4107Z8V Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) FD724_RS01845 ENOG4105BZU Histidine kinase FD724_RS01860 ENOG4105FIK Inherit from COG: dihydropteroate synthase FD724_RS01870 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) FD724_RS01880 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) FD724_RS01895 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FD724_RS01910 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FD724_RS01915 ENOG4105F4R Transcriptional regulator mode FD724_RS01935 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) FD724_RS02005 ENOG4107SBE Glycosyl transferase (Group 1 FD724_RS02025 ENOG4105EGD dinuclear metal center protein, YbgI family FD724_RS02045 ENOG4105C9B Cysteine desulfurase FD724_RS02080 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) FD724_RS02110 ENOG4107RAQ aminopeptidase FD724_RS02125 ENOG4105DDQ anthranilate synthase FD724_RS02135 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) FD724_RS02160 ENOG4105HFZ Membrane FD724_RS02185 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) FD724_RS02190 ENOG4105BZU Histidine kinase FD724_RS02215 ENOG4105D7T ABC transporter FD724_RS02230 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FD724_RS02235 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FD724_RS02255 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) FD724_RS02300 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase FD724_RS02305 ENOG4105ENT Efflux transporter rnd family, mfp subunit FD724_RS02335 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) FD724_RS02360 ENOG4105D8X mechanosensitive ion channel FD724_RS02370 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS02385 ENOG4107RJ7 Glycosyl transferase (Group 1 FD724_RS02390 ENOG4105K64 Glycosyl transferase, family 2 FD724_RS02395 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS02405 ENOG4105BZ1 (ABC) transporter FD724_RS02410 ENOG4105D3Q Sugar transferase FD724_RS02415 ENOG4107YJ4 chain length determinant protein FD724_RS02420 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS02435 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FD724_RS02445 ENOG4107XZA Glycosyl transferase family 2 FD724_RS02455 ENOG4105CMR udp-glucose 4-epimerase FD724_RS02460 ENOG4105D5U fad dependent oxidoreductase FD724_RS02465 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase FD724_RS02480 ENOG4108M24 von Willebrand factor, type A FD724_RS02600 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS02605 ENOG4105BZU Histidine kinase FD724_RS02645 ENOG4108Z5K methylglyoxal synthase FD724_RS02695 ENOG41062JF Transcriptional regulator FD724_RS02715 ENOG4108IUZ ABC transporter FD724_RS02765 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FD724_RS02790 ENOG4105H0Z Hemerythrin HHE cation binding domain protein FD724_RS02805 ENOG4107WDG serine threonine protein kinase FD724_RS02810 ENOG410848W 30S ribosomal protein S21 FD724_RS02815 ENOG4105VFU Rna-binding protein FD724_RS02830 ENOG41063FQ CsbD-like protein FD724_RS02870 ENOG41065RQ ADP-ribosylation crystallin J1 FD724_RS02900 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) FD724_RS02905 ENOG4108YZ9 Urea amidohydrolase subunit gamma FD724_RS02910 ENOG4105KI2 Urea amidohydrolase subunit beta FD724_RS02920 ENOG4105CQM Urea amidohydrolase subunit alpha FD724_RS02945 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) FD724_RS02965 ENOG4105BZU Histidine kinase FD724_RS02970 ENOG4105C26 Dehydrogenase FD724_RS02980 ENOG41068G9 50S ribosomal protein L32 FD724_RS03005 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FD724_RS03015 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FD724_RS03020 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FD724_RS03025 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) FD724_RS03040 ENOG4105FDP GntR family transcriptional regulator FD724_RS03050 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FD724_RS03090 ENOG4108JJA ABC, transporter FD724_RS03125 ENOG4105C5S asparaginyl-tRNA synthetase FD724_RS03145 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FD724_RS03150 ENOG4108S1Y allophycocyanin alpha-B chain FD724_RS03160 ENOG4107QIK phosphoribosylformylglycinamidine synthase FD724_RS03165 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FD724_RS03190 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) FD724_RS03205 ENOG4108JQC penicillin-binding protein 1A FD724_RS03215 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) FD724_RS03220 ENOG4107ZYJ bioY protein FD724_RS03230 ENOG4105C8U phosphate abc transporter FD724_RS03235 ENOG4105E2Z phosphate ABC transporter (Permease FD724_RS03240 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FD724_RS03275 ENOG4105CIH Imidazole acetol-phosphate transaminase FD724_RS03285 ENOG4105DC8 reductase FD724_RS03300 ENOG4105KHC sulfurtransferase FD724_RS03305 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) FD724_RS03310 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS03315 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) FD724_RS03325 ENOG4105D44 asparaginase FD724_RS03360 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) FD724_RS03385 ENOG4107U9K TROVE domain-containing protein FD724_RS03405 ENOG4105CNF WD-40 repeat protein FD724_RS03410 ENOG4105DC8 reductase FD724_RS03490 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) FD724_RS03495 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) FD724_RS03500 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FD724_RS03510 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FD724_RS03520 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving FD724_RS03530 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) FD724_RS03550 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS03555 ENOG4105BZU Histidine kinase FD724_RS03585 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) FD724_RS03620 ENOG4105WGP Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity) FD724_RS03640 ENOG4105E4F Isochorismate synthase FD724_RS03650 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) FD724_RS03655 ENOG4105BZU Histidine kinase FD724_RS03665 ENOG4107R0W ABC transporter FD724_RS03690 ENOG4108FN7 Aldo keto reductase FD724_RS03695 ENOG4105C3J Cysteine desulfurase FD724_RS03705 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FD724_RS03710 ENOG4105CVP deoxyribo-dipyrimidine photolyase FD724_RS03720 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FD724_RS03725 ENOG41081F0 Precorrin-8x methylmutase FD724_RS03730 ENOG4105DVK Precorrin-2 c20-methyltransferase FD724_RS03735 ENOG4107YCR Transcriptional regulator, ARSR family FD724_RS03745 ENOG4105D6J arsenicaL-resistance protein FD724_RS03765 ENOG4105CXB phosphoribosylaminoimidazole synthetase FD724_RS03775 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FD724_RS03785 ENOG4105K6T rare lipoprotein A FD724_RS03790 ENOG4105CSV Glutaminase FD724_RS03805 ENOG4105BZU Histidine kinase FD724_RS03810 ENOG4105D74 hydrolase FD724_RS03820 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FD724_RS03825 ENOG4106Z1T Nicotinamide Mononucleotide Transporter FD724_RS03850 ENOG4105D3G Pseudouridine synthase FD724_RS03875 ENOG4105GVF (ABC) transporter FD724_RS03880 ENOG4108DBC nitroreductase FD724_RS03910 ENOG41085RW This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) FD724_RS03915 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis FD724_RS03975 ENOG4105CNW domain protein FD724_RS03985 ENOG4105CNW domain protein FD724_RS03990 ENOG410841Q phosphoesterase PA-phosphatase related protein FD724_RS04015 ENOG4105C59 p-type ATPase FD724_RS04030 ENOG4105CJ1 ABC, transporter FD724_RS04070 ENOG4107EFQ arachidonate 15-lipoxygenase FD724_RS04085 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FD724_RS04110 ENOG4105CFG Acts as a chaperone (By similarity) FD724_RS04135 ENOG4105X25 FD724_RS04145 ENOG4105CF7 AraC family transcriptional regulator FD724_RS04165 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FD724_RS04170 ENOG4105ENX hydrolase FD724_RS04175 ENOG4105EMU Dehydrogenase FD724_RS04180 ENOG4107SET aldo keto reductase FD724_RS04185 ENOG4105BZ1 (ABC) transporter FD724_RS04230 ENOG4105BZS acriflavin resistance protein FD724_RS04265 ENOG4105BZU Histidine kinase FD724_RS04270 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS04305 ENOG4105EUB pirin domain protein FD724_RS04380 ENOG4108UV1 cellular component movement FD724_RS04395 ENOG4108UN4 phage SPO1 DNA polymerase-related protein FD724_RS04420 ENOG4105CSR polyphosphate kinase 2 FD724_RS04425 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FD724_RS04430 ENOG4105BZU Histidine kinase FD724_RS04460 ENOG41081UC Inherit from COG: Competence protein FD724_RS04470 ENOG4107Z12 Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) FD724_RS04480 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) FD724_RS04485 ENOG4107DVA This protein is a component of the reaction center of photosystem II (By similarity) FD724_RS04495 ENOG41069TS Photosystem II reaction center protein M FD724_RS04505 ENOG4105DGI Alkaline phosphatase FD724_RS04525 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FD724_RS04550 ENOG4105C5H ABC transporter FD724_RS04565 ENOG4108ZF3 Phosphatase FD724_RS04620 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FD724_RS04625 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FD724_RS04635 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS04645 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FD724_RS04660 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FD724_RS04665 ENOG4108R6B Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FD724_RS04675 ENOG4105C0K Gdp-mannose 4,6-dehydratase FD724_RS04680 ENOG4105JNK Glycosyl transferase (Group 1 FD724_RS04690 ENOG4105ZDA FD724_RS04735 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FD724_RS04740 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FD724_RS04755 ENOG4105DKQ ROK family FD724_RS04780 ENOG4105WCA Ferredoxin FD724_RS04810 ENOG4105ND9 Nitrogenase-associated protein FD724_RS04865 ENOG4105CNF WD-40 repeat protein FD724_RS04880 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FD724_RS04885 ENOG4105C45 hydrogenase expression formation protein (HypE) FD724_RS04890 ENOG4105CQS hydrogenase expression formation protein HypD FD724_RS04895 ENOG41082MF Hydrogenase assembly chaperone hypC hupF FD724_RS04900 ENOG4105C8H hydrogenase maturation protein Hypf FD724_RS04935 ENOG4105DPX Hydrogenase, large subunit FD724_RS05020 ENOG4105R88 May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity) FD724_RS05025 ENOG4105X87 nitrogen fixation FD724_RS05030 ENOG4108VQE nitrogen fixation protein FD724_RS05035 ENOG4108UR2 Nitrogen fixation protein NifX FD724_RS05040 ENOG4105DK8 Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN FD724_RS05045 ENOG4105D0B Nitrogenase protein alpha chain FD724_RS05055 ENOG4105CY9 nitrogenase molybdenum-iron protein beta chain FD724_RS05135 ENOG4108S59 FD724_RS05190 ENOG4105CSR polyphosphate kinase 2 FD724_RS05200 ENOG4105GC4 N-4 methylation of cytosine FD724_RS05205 ENOG4108NAW Type II site-specific deoxyribonuclease FD724_RS05210 ENOG4105D0B Nitrogenase protein alpha chain FD724_RS05225 ENOG4107RIU May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity) FD724_RS05295 ENOG4105D7W serine acetyltransferase FD724_RS05310 ENOG4107S73 homocitrate synthase FD724_RS05365 ENOG4107QP0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) FD724_RS05375 ENOG4107YCR Transcriptional regulator, ARSR family FD724_RS05380 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FD724_RS05385 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FD724_RS05400 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FD724_RS05415 ENOG4105DFU Cell wall formation (By similarity) FD724_RS05420 ENOG4105D4A Cell wall formation (By similarity) FD724_RS05425 ENOG41082EZ Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) FD724_RS05435 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FD724_RS05440 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) FD724_RS05455 ENOG4105BZU Histidine kinase FD724_RS05520 ENOG4108M15 ABC transporter FD724_RS05535 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FD724_RS05545 ENOG4105XEV csbD-like FD724_RS05580 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FD724_RS05585 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS05610 ENOG4105CXN decarboxylase FD724_RS05630 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FD724_RS05640 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) FD724_RS05665 ENOG4105CVN desaturase FD724_RS05710 ENOG4105C59 p-type ATPase FD724_RS05810 ENOG4105BZU Histidine kinase FD724_RS05815 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS05860 ENOG4108STX response regulator FD724_RS05885 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS05900 ENOG4108TQ9 Histidine kinase FD724_RS05915 ENOG4105C3G gtp-binding protein FD724_RS05925 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) FD724_RS05940 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) FD724_RS05950 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FD724_RS05965 ENOG4108UXN response regulator FD724_RS05990 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FD724_RS05995 ENOG4105C19 ABC transporter FD724_RS06045 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FD724_RS06130 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FD724_RS06140 ENOG41084IE Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FD724_RS06175 ENOG4108PWY Carbohydrate-selective porin OprB FD724_RS06190 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FD724_RS06240 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FD724_RS06245 ENOG4105DZ0 fad dependent oxidoreductase FD724_RS06250 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FD724_RS06260 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS06290 ENOG4107EFQ arachidonate 15-lipoxygenase FD724_RS06295 ENOG4105CPC Aldo Keto reductase FD724_RS06305 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FD724_RS06355 ENOG4108FN7 Aldo keto reductase FD724_RS06360 ENOG4105PYN Pyridoxamine 5-phosphate oxidase-related FD724_RS06400 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 FD724_RS06415 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FD724_RS07390 ENOG4105WVZ Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FD724_RS07435 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FD724_RS07440 ENOG4105K70 DNA-binding protein FD724_RS07650 ENOG4105DFK Polyphosphate glucokinase FD724_RS07660 ENOG4107STW synthase FD724_RS07710 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FD724_RS07735 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) FD724_RS07760 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FD724_RS07765 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FD724_RS07770 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) FD724_RS07785 ENOG4105CAQ asparagine synthetase FD724_RS07810 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FD724_RS07820 ENOG4108302 MgtC SapB transporter FD724_RS07825 ENOG4105E0X reductase FD724_RS07830 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FD724_RS07835 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase FD724_RS07840 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FD724_RS07860 ENOG41080E3 single-stranded DNA-binding protein FD724_RS07865 ENOG4105DFF Rod shape-determining protein mreb FD724_RS07915 ENOG4108MV2 Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity) FD724_RS07950 ENOG4105CMQ Chloride channel FD724_RS07955 ENOG4105D75 Capsular exopolysaccharide family FD724_RS08040 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS08045 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS08065 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) FD724_RS08075 ENOG4105EWN Heme oxygenase FD724_RS08080 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) FD724_RS08100 ENOG4107RGC Glycosyl transferase, family 2 FD724_RS08105 ENOG4105CPK Glycosyl transferase (Group 1 FD724_RS08110 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS08125 ENOG4105D3R alkyl hydroperoxide reductase FD724_RS08135 ENOG410890F Dynamin family FD724_RS08140 ENOG410890F Dynamin family FD724_RS08200 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) FD724_RS08245 ENOG4107QRP cobalamin biosynthesis protein CobW FD724_RS08285 ENOG4105C6X Major Facilitator FD724_RS08290 ENOG4105CKK Glycosyl transferase, family 2 FD724_RS08335 ENOG4105DKQ ROK family FD724_RS08345 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FD724_RS08360 ENOG4105C3M thioredoxin reductase FD724_RS08375 ENOG4108D32 Methyltransferase FD724_RS08380 ENOG4106855 Competence protein FD724_RS08400 ENOG4105FJR Lmbe family FD724_RS08420 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FD724_RS08430 ENOG4105D2T synthase FD724_RS08445 ENOG4107TY6 Acylneuraminate cytidylyltransferase FD724_RS08450 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FD724_RS08455 ENOG4105C5E polysaccharide biosynthesis protein FD724_RS08480 ENOG4107R0W ABC transporter FD724_RS08485 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FD724_RS08490 ENOG4105C8M UPF0272 protein FD724_RS08495 ENOG4107RTD sua5 ycio yrdc ywlc family protein FD724_RS08520 ENOG41082QS Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) FD724_RS08535 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FD724_RS08540 ENOG4105PGM cation diffusion facilitator family transporter FD724_RS08550 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FD724_RS08555 ENOG4107EXC regulatoR FD724_RS08560 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FD724_RS08565 ENOG4107VQD May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity) FD724_RS08605 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FD724_RS08610 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FD724_RS08620 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) FD724_RS08640 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FD724_RS08660 ENOG4108PWY Carbohydrate-selective porin OprB FD724_RS08665 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) FD724_RS08675 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase FD724_RS08695 ENOG4108KKY Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin (By similarity) FD724_RS08700 ENOG4108QAI Catalyzes the two-electron reduction of biliverdin IX- alpha at the C15 methine bridge (By similarity) FD724_RS08705 ENOG4108SCB Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) FD724_RS08735 ENOG4108U42 Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) FD724_RS08755 ENOG4108PWY Carbohydrate-selective porin OprB FD724_RS08775 ENOG4108SMZ Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) FD724_RS08825 ENOG4105FBW Monooxygenase FD724_RS08830 ENOG4108UZX fmn reductase FD724_RS08835 ENOG4105CQB FAD linked oxidase domain protein FD724_RS08840 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FD724_RS08855 ENOG4108HMN Caspase domain FD724_RS08855 ENOG4108HMN Caspase domain FD724_RS08895 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FD724_RS08910 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FD724_RS08960 ENOG4105C7B Threonine dehydratase FD724_RS08965 ENOG4105VFU Rna-binding protein FD724_RS08975 ENOG4105CPC Aldo Keto reductase FD724_RS08980 ENOG4107XM9 (LipO)protein FD724_RS09010 ENOG4105FBB Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity) FD724_RS09050 ENOG4105D06 uba thif-type nad fad binding protein FD724_RS09065 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FD724_RS09070 ENOG4105DJY efflux transporter, rnd family, mfp subunit FD724_RS09105 ENOG4107QRG dna polymerase iii FD724_RS09135 ENOG4108IQK o-acetylhomoserine FD724_RS09140 ENOG4105DWV Homoserine O-trans-acetylase FD724_RS09160 ENOG4107URF beta-phospho-glucomutase FD724_RS09165 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FD724_RS09170 ENOG4105E0Y RtcB Protein FD724_RS09170 ENOG4105E0Y RtcB Protein FD724_RS09200 ENOG4108IQE Amp-dependent synthetase and ligase FD724_RS09225 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E FD724_RS09230 ENOG4105EQ0 Major Facilitator superfamily FD724_RS09240 ENOG4105C9U ATP-dependent DNA helicase RecQ FD724_RS09275 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) FD724_RS09285 ENOG4105DBI uridine monophosphokinase FD724_RS09295 ENOG4105W5Q DNA repair protein (RadC FD724_RS09405 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FD724_RS09410 ENOG4108PWY Carbohydrate-selective porin OprB FD724_RS09440 ENOG4105BZU Histidine kinase FD724_RS09445 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS09495 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS09500 ENOG41089UC methyltransferase, type 11 FD724_RS09505 ENOG4107QXV Phosphate transporter FD724_RS09530 ENOG4105KAK Plasmid pRiA4b ORF-3 family protein FD724_RS09540 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off FD724_RS09555 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FD724_RS09590 ENOG4105TQG cytochrome C, class I FD724_RS09660 ENOG4105BZU Histidine kinase FD724_RS09680 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) FD724_RS09685 ENOG4105BZU Histidine kinase FD724_RS09715 ENOG41061CK Antibiotic biosynthesis monooxygenase FD724_RS09720 ENOG4107QI1 Mate efflux family protein FD724_RS09740 ENOG4105BZU Histidine kinase FD724_RS09755 ENOG4107XWZ ferric uptake regulator FD724_RS09760 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FD724_RS09770 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FD724_RS09880 ENOG4105I7S Abortive infection protein FD724_RS09900 ENOG4107WDG serine threonine protein kinase FD724_RS09945 ENOG4105FQP Beta-lactamase FD724_RS10020 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FD724_RS10025 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FD724_RS10050 ENOG4105BZU Histidine kinase FD724_RS10075 ENOG4105D9P serine threonine protein kinase FD724_RS10080 ENOG4107QIZ NADH dehydrogenase FD724_RS10090 ENOG4107R1X phosphohexokinase FD724_RS10095 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FD724_RS10100 ENOG4105BZU Histidine kinase FD724_RS10130 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) FD724_RS10160 ENOG4105C0W non-ribosomal peptide synthetase FD724_RS10200 ENOG4107QRA Extracellular solute-binding protein, family 5 FD724_RS10225 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FD724_RS10245 ENOG4105CD5 CoA-binding domain protein FD724_RS10275 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FD724_RS10305 ENOG4107QWP ABC-2 type transporter FD724_RS10310 ENOG4105CJ1 ABC, transporter FD724_RS10315 ENOG4105CJ1 ABC, transporter FD724_RS10330 ENOG4105VN1 Heat shock protein FD724_RS10365 ENOG4105BZU Histidine kinase FD724_RS10370 ENOG4107WMZ Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) FD724_RS10375 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS10380 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FD724_RS10390 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FD724_RS10400 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FD724_RS10410 ENOG4108YZN class I peptide chain release factor FD724_RS10435 ENOG4105BZU Histidine kinase FD724_RS10450 ENOG4105BZU Histidine kinase FD724_RS10455 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS10460 ENOG4107WDG serine threonine protein kinase FD724_RS10465 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FD724_RS10470 ENOG4107TUY Histidine kinase FD724_RS10505 ENOG4107SCA Formamidase (EC 3.5.1.49) FD724_RS10505 ENOG4107SCA Formamidase (EC 3.5.1.49) FD724_RS10515 ENOG4108YYH Nadph-dependent fmn reductase FD724_RS10525 ENOG4105E09 nadh pyrophosphatase FD724_RS10530 ENOG4105CDA abc transporter atp-binding protein FD724_RS10535 ENOG4108HW3 (ABC) transporter FD724_RS10540 ENOG41084M5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FD724_RS10545 ENOG4105ECY inositol monophosphatase FD724_RS10595 ENOG4105CHM Aminotransferase FD724_RS10655 ENOG4105C32 Amino acid ABC transporter (Permease) FD724_RS10665 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FD724_RS10670 ENOG4105C0Z ABC transporter FD724_RS10685 ENOG4108IV0 ABC, transporter FD724_RS10700 ENOG4105CHC glucokinase (EC 2.7.1.2) FD724_RS10730 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FD724_RS10735 ENOG4105D0S secretion protein (HlyD FD724_RS10740 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FD724_RS10755 ENOG4105C31 Tryptophanyl-tRNA synthetase FD724_RS10845 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) FD724_RS10880 ENOG4108JJA ABC, transporter FD724_RS10885 ENOG4108JJA ABC, transporter FD724_RS10925 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FD724_RS10930 ENOG4105BZU Histidine kinase FD724_RS10955 ENOG4105BZU Histidine kinase FD724_RS10965 ENOG4105XRQ Xanthine dehydrogenase accessory factor FD724_RS10980 ENOG4105C7W Xanthine dehydrogenase FD724_RS10985 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding FD724_RS10990 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit FD724_RS11000 ENOG4108K5P (LipO)protein FD724_RS11020 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) FD724_RS11025 ENOG4105DKP glycosyl transferase, family 9 FD724_RS11065 ENOG4105CIH Imidazole acetol-phosphate transaminase FD724_RS11070 ENOG4105K70 DNA-binding protein FD724_RS11075 ENOG4105GVR general secretion pathway protein D FD724_RS11100 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FD724_RS11170 ENOG4106H78 methyltransferase FD724_RS11175 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FD724_RS11185 ENOG4105EKQ RNA-directed DNA polymerase FD724_RS11190 ENOG4105VU5 Resolvase domain-containing protein FD724_RS11210 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FD724_RS11215 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FD724_RS11230 ENOG41084H8 Binds directly to 16S ribosomal RNA (By similarity) FD724_RS11240 ENOG4107YZX Universal stress protein FD724_RS11250 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FD724_RS11260 ENOG4106KE4 Dehydrogenase FD724_RS11310 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FD724_RS11320 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) FD724_RS11430 ENOG4105DGU Histone deacetylase FD724_RS11445 ENOG4105C09 Bile acid FD724_RS11465 ENOG4107QQ4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) FD724_RS11480 ENOG4108RXX maleylacetoacetate isomerase FD724_RS11505 ENOG4105DR5 peptidase FD724_RS11515 ENOG4106PVI ATP-dependent carboxylate-amine ligase (By similarity) FD724_RS11525 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FD724_RS11535 ENOG410906A Beta-Ig-H3 fasciclin FD724_RS11540 ENOG4105WXN Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) FD724_RS11610 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr FD724_RS11620 ENOG4105CPQ Dehydrogenase FD724_RS11625 ENOG4107FQX Alpha-acetolactate decarboxylase FD724_RS11650 ENOG4105CVJ phosphoglycerate mutase FD724_RS11700 ENOG4105ES5 Histidine kinase FD724_RS11705 ENOG4105MMR Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity) FD724_RS11710 ENOG4108YH3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) FD724_RS11720 ENOG4108JQ6 ABC transporter FD724_RS11735 ENOG4105EKQ RNA-directed DNA polymerase FD724_RS11750 ENOG4108IJ9 (ABC) transporter FD724_RS11760 ENOG4105BZA Phosphoglycerate kinase FD724_RS11780 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FD724_RS11830 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) FD724_RS11835 ENOG4105EBH Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity) FD724_RS11840 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) FD724_RS11845 ENOG4105BZU Histidine kinase FD724_RS11850 ENOG4105F8J Adenylate Guanylate cyclase FD724_RS11935 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction FD724_RS11940 ENOG4105CPC Aldo Keto reductase FD724_RS12065 ENOG410600T transposase FD724_RS12100 ENOG4105D49 3-dehydroquinate synthase FD724_RS12110 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) FD724_RS12140 ENOG4105D74 hydrolase FD724_RS12150 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) FD724_RS12175 ENOG4105K46 50S ribosomal protein l27 FD724_RS12180 ENOG41082FX This protein binds to 23S rRNA in the presence of protein L20 (By similarity) FD724_RS12200 ENOG4105EET magnesium chelatase FD724_RS12210 ENOG4105NI8 Cytosine-specific methyltransferase FD724_RS12250 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FD724_RS12295 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) FD724_RS12315 ENOG4105CAS nag kinase FD724_RS12335 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FD724_RS12340 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) FD724_RS12360 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) FD724_RS12365 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) FD724_RS12370 ENOG4107TS3 membrane protein, TerC FD724_RS12395 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FD724_RS12420 ENOG4105CYM Glutathione S-transferase FD724_RS12435 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FD724_RS12455 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FD724_RS12460 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FD724_RS12465 ENOG4105K63 Thioredoxin FD724_RS12470 ENOG4105YVS arsR family transcriptional regulator FD724_RS12485 ENOG4105CND Glycosyl transferase, family 2 FD724_RS12490 ENOG4105EWU Squalene--hopene cyclase FD724_RS12525 ENOG4107R7Y intracellular protease Pfpi family FD724_RS12555 ENOG4105CXI aluminum resistance protein FD724_RS12580 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FD724_RS12585 ENOG4105BZU Histidine kinase FD724_RS12630 ENOG4105C7Z Conserved Protein FD724_RS12635 ENOG410801B Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FD724_RS12645 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FD724_RS12665 ENOG4105E3B Multicopper oxidase FD724_RS12685 ENOG4105DKF Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity) FD724_RS12715 ENOG410841Q phosphoesterase PA-phosphatase related protein FD724_RS12720 ENOG4105J0U photosystem II FD724_RS12735 ENOG410667J hydrolase FD724_RS12760 ENOG4105CVA phosphate FD724_RS12780 ENOG4105K63 Thioredoxin FD724_RS12815 ENOG4105C8S subunit m FD724_RS12885 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) FD724_RS12905 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FD724_RS12910 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FD724_RS12915 ENOG4108302 MgtC SapB transporter FD724_RS12955 ENOG4108JJB ABC transporter FD724_RS12965 ENOG4105G01 cobalamin (vitamin B12) biosynthesis CbiM protein FD724_RS12980 ENOG4105BZU Histidine kinase FD724_RS12995 ENOG4108PWY Carbohydrate-selective porin OprB FD724_RS13005 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) FD724_RS13010 ENOG4108JH3 FD724_RS13015 ENOG4105C72 UPF0176 protein FD724_RS13025 ENOG4105C0D helicase FD724_RS13045 ENOG4105BZU Histidine kinase FD724_RS13060 ENOG4105MSY salicylate hydroxylase FD724_RS13075 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) FD724_RS13080 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FD724_RS13105 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) FD724_RS13120 ENOG4107ZYR domain protein FD724_RS13125 ENOG4105CZN Potassium uptake protein FD724_RS13135 ENOG4105E0A ABC, transporter FD724_RS13160 ENOG4105BZU Histidine kinase FD724_RS13175 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FD724_RS13180 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FD724_RS13185 ENOG4105M3Z response regulator FD724_RS13215 ENOG4105F38 ABC transporter, permease FD724_RS13220 ENOG4107RUE extracellular solute-binding protein family 1 FD724_RS13235 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FD724_RS13240 ENOG4105E0U tyrosine-specific transport protein FD724_RS13245 ENOG4105BZU Histidine kinase FD724_RS13260 ENOG4107VAM peptidase, m28 FD724_RS13275 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FD724_RS13295 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FD724_RS13300 ENOG4105C8B TIGR00159 family FD724_RS13310 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FD724_RS13335 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) FD724_RS13365 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FD724_RS13405 ENOG4105C8Q Methyl-accepting chemotaxis FD724_RS13430 ENOG4107UAN Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FD724_RS13445 ENOG4105CRE cytochrome C FD724_RS13475 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FD724_RS13485 ENOG4106AG1 Involved in the binding and or turnover of quinones at the Q(B) site of Photosystem II (By similarity) FD724_RS13505 ENOG4105E33 succinate dehydrogenase FD724_RS13525 ENOG4105C3M thioredoxin reductase FD724_RS13530 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) FD724_RS13535 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FD724_RS13540 ENOG4107QX9 Thiol disulfide interChange protein FD724_RS13595 ENOG4105CQB FAD linked oxidase domain protein FD724_RS13650 ENOG4105K64 Glycosyl transferase, family 2 FD724_RS13655 ENOG4108IAJ Nad-dependent epimerase dehydratase FD724_RS13670 ENOG410600T transposase FD724_RS13715 ENOG4105M3Z response regulator FD724_RS13730 ENOG4105MRC Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth FD724_RS13740 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FD724_RS13755 ENOG4105W2E Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity) FD724_RS13795 ENOG4108HMN Caspase domain FD724_RS13855 ENOG4105BZU Histidine kinase FD724_RS13860 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS13865 ENOG4105BZU Histidine kinase FD724_RS13875 ENOG4105BZ4 penicillin-binding protein FD724_RS13885 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS13900 ENOG4108E2B had-superfamily hydrolase, subfamily iib FD724_RS13925 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) FD724_RS13955 ENOG4108M4U conserved membrane protein FD724_RS13960 ENOG4107WCA isomerase FD724_RS13965 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FD724_RS14000 ENOG4105ETX regulatoR FD724_RS14005 ENOG4105BZU Histidine kinase FD724_RS14015 ENOG4105D64 Mechanosensitive ion channel FD724_RS14145 ENOG4105DC1 bifunctional purine biosynthesis protein purh FD724_RS14155 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FD724_RS14165 ENOG4105FFC UPF0187 protein FD724_RS14175 ENOG4107WDG serine threonine protein kinase FD724_RS14185 ENOG4105CJ1 ABC, transporter FD724_RS14200 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FD724_RS14205 ENOG4108KGH TRANSCRIPTIONal FD724_RS14240 ENOG4107KHP This protein is a component of the reaction center of photosystem II (By similarity) FD724_RS14245 ENOG4105EVB acetyltransferase FD724_RS14290 ENOG4105C19 ABC transporter FD724_RS14320 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FD724_RS14325 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS14335 ENOG4105CAK Cell division ATP-binding protein ftsE FD724_RS14400 ENOG4105BZU Histidine kinase FD724_RS14415 ENOG4108FYC transcriptional regulator MERR family FD724_RS14495 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FD724_RS14505 ENOG4105E4C Lytic transglycosylase catalytic FD724_RS14525 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) FD724_RS14545 ENOG4105C0H protease FD724_RS14560 ENOG4105C0H protease FD724_RS14565 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS14570 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 FD724_RS14620 ENOG4105C01 Dihydroxy-acid dehydratase FD724_RS14625 ENOG4107RSM transcriptional regulator FD724_RS14635 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FD724_RS14645 ENOG4105D0B Nitrogenase protein alpha chain FD724_RS14650 ENOG4105DK8 Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN FD724_RS14675 ENOG4108FYC transcriptional regulator MERR family FD724_RS14695 ENOG4105FDT acyl-CoA dehydrogenase FD724_RS14755 ENOG4107EEY synthase FD724_RS14770 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FD724_RS14775 ENOG4108KQ6 Enoyl-CoA hydratase FD724_RS14780 ENOG4108MGH Enoyl-CoA hydratase FD724_RS14785 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase FD724_RS14845 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FD724_RS14860 ENOG4105CDY transcriptional regulatory protein FD724_RS14885 ENOG4107SC1 transglycosylase FD724_RS14930 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FD724_RS14970 ENOG4108HCJ Hydrolase FD724_RS14985 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FD724_RS15030 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) FD724_RS15040 ENOG4107YX3 NADH dehydrogenase subunit j FD724_RS15045 ENOG41082X4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FD724_RS15085 ENOG4108SHN Glycosyl transferase, family 2 FD724_RS15090 ENOG4106WTF Glycosyl transferase, family 2 FD724_RS15095 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF FD724_RS15115 ENOG4105CPQ Dehydrogenase FD724_RS15125 ENOG4105CD3 dihydroorotase FD724_RS15145 ENOG4105D4Y metalloprotease FD724_RS15150 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FD724_RS15155 ENOG4108KK4 3-dehydroquinate synthase FD724_RS15170 ENOG4105CPF Cell wall formation (By similarity) FD724_RS15195 ENOG4105C0R drug resistance transporter emrb qaca subfamily FD724_RS15200 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) FD724_RS15215 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FD724_RS15220 ENOG4105K63 Thioredoxin FD724_RS15225 ENOG41076UM multiple antibiotic resistance (MarC)-related protein FD724_RS15250 ENOG4105Y7M Transcriptional regulator, TetR family FD724_RS15255 ENOG4105DTD Dehydrogenase FD724_RS15270 ENOG4108JYK Dehydrogenase FD724_RS15285 ENOG4105E67 Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings) FD724_RS15300 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FD724_RS15325 ENOG4105CE9 30S ribosomal protein S2 FD724_RS15330 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) FD724_RS15360 ENOG4105CDH Citrulline--aspartate ligase FD724_RS15380 ENOG41082BG Binds together with S18 to 16S ribosomal RNA (By similarity) FD724_RS15415 ENOG4106DN3 This protein is a component of the reaction center of photosystem II (By similarity) FD724_RS15425 ENOG410689D This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity) FD724_RS15430 ENOG4105NT3 This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity) FD724_RS15440 ENOG410828V rubredoxin FD724_RS15445 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FD724_RS15450 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FD724_RS15455 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FD724_RS15560 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FD724_RS15585 ENOG4105CMT Dihydroxyacetone kinase FD724_RS15590 ENOG4108UTZ Dihydroxyacetone kinase FD724_RS15595 ENOG4108Z03 MAF-like protein FD724_RS15610 ENOG4105CPC Aldo Keto reductase FD724_RS15630 ENOG4108R0D protein with myosin-like FD724_RS15635 ENOG4107RU9 Transcriptional regulator, Crp Fnr family FD724_RS15640 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FD724_RS15645 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FD724_RS15650 ENOG4105DA5 (ABC) transporter FD724_RS15655 ENOG4105DAY polysaccharide export protein FD724_RS15675 ENOG4105CG5 Glycosyl transferase (Group 1 FD724_RS15685 ENOG4105K64 Glycosyl transferase, family 2 FD724_RS15695 ENOG4105D3Q Sugar transferase FD724_RS15700 ENOG4105CEY Amp-dependent synthetase and ligase FD724_RS15705 ENOG4105CV8 reductase FD724_RS15765 ENOG4108JJB ABC transporter FD724_RS15770 ENOG4107YBR Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) FD724_RS15780 ENOG4108IJ9 (ABC) transporter FD724_RS15795 ENOG4108HMX isocitrate dehydrogenase (NADP) FD724_RS15800 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) FD724_RS15820 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) FD724_RS15830 ENOG4105CPC Aldo Keto reductase FD724_RS15865 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FD724_RS15890 ENOG4105T2N Domain of unknown function (DUF2382) FD724_RS15900 ENOG4107RIQ Sulfate adenylate transferase FD724_RS15925 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FD724_RS15985 ENOG4105CMS peptidase U62, modulator of DNA gyrase FD724_RS15995 ENOG4105CKK Glycosyl transferase, family 2 FD724_RS16000 ENOG4105EWK phytoene FD724_RS16005 ENOG41060GT Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) FD724_RS16025 ENOG4105BZM domain protein FD724_RS16050 ENOG4105CUT histidyl-tRNA synthetase FD724_RS16085 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FD724_RS16090 ENOG4107YJ4 chain length determinant protein FD724_RS16095 ENOG4105JFG SpoIID LytB domain protein FD724_RS16115 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family FD724_RS16140 ENOG4105D0M Protease HtpX homolog FD724_RS16175 ENOG4105C0F tryptophanase EC 4.1.99.1 FD724_RS16200 ENOG4105D49 3-dehydroquinate synthase FD724_RS16210 ENOG4107QSQ Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) FD724_RS16215 ENOG4105D9U N-acetyltransferase FD724_RS16230 ENOG4105CNG UPF0061 protein FD724_RS16240 ENOG4105CVJ phosphoglycerate mutase FD724_RS16245 ENOG4105BZ1 (ABC) transporter FD724_RS16280 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) FD724_RS16290 ENOG4105WDY DNA (cytosine-5-)-methyltransferase FD724_RS16315 ENOG4105D7W serine acetyltransferase FD724_RS16335 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) FD724_RS16350 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FD724_RS16355 ENOG4105D9P serine threonine protein kinase FD724_RS16375 ENOG41087PP glycosyltransferase MGT family FD724_RS16385 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FD724_RS16440 ENOG4105DXX methyltransferase FD724_RS16465 ENOG4105E0K tonB-dependent siderophore receptor FD724_RS16520 ENOG4108IXY short-chain dehydrogenase reductase FD724_RS16565 ENOG4105C5I Dehydrogenase FD724_RS16570 ENOG4108JQ1 Dehydrogenase FD724_RS16580 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FD724_RS16585 ENOG4105FBW Monooxygenase FD724_RS16590 ENOG4108PWY Carbohydrate-selective porin OprB FD724_RS16595 ENOG4108RSN SNARE associated Golgi FD724_RS16630 ENOG4105GVF (ABC) transporter FD724_RS16645 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) FD724_RS16660 ENOG4105GVF (ABC) transporter FD724_RS16665 ENOG4105GVF (ABC) transporter FD724_RS16705 ENOG4108JUB Transcriptional regulator FD724_RS16725 ENOG4105C22 threonyL-tRNA synthetase FD724_RS16740 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FD724_RS16745 ENOG4107Z3D 50S ribosomal protein l10 FD724_RS16755 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) FD724_RS16775 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FD724_RS16780 ENOG4105K64 Glycosyl transferase, family 2 FD724_RS16785 ENOG4107SVH Potassium channel protein FD724_RS16805 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) FD724_RS16810 ENOG4107RSM transcriptional regulator FD724_RS16835 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) FD724_RS16855 ENOG4105BZU Histidine kinase FD724_RS16860 ENOG4105ETX regulatoR FD724_RS16885 ENOG4108Z6M essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn FD724_RS16915 ENOG4105D0M Protease HtpX homolog FD724_RS16930 ENOG4105CRK lysyL-tRNA synthetase FD724_RS16975 ENOG4105BZU Histidine kinase FD724_RS17010 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FD724_RS17040 ENOG4105BZU Histidine kinase FD724_RS17090 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) FD724_RS17100 ENOG4105CHV Transcription elongation factor NusA FD724_RS17105 ENOG4107ZR3 Required for maturation of 30S ribosomal subunits (By similarity) FD724_RS17125 ENOG4108UGD Serine Threonine protein kinase FD724_RS17145 ENOG4108UGD Serine Threonine protein kinase FD724_RS17190 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FD724_RS17195 ENOG4105M6F mutator MutT protein FD724_RS17205 ENOG4105WVZ Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FD724_RS17210 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FD724_RS17215 ENOG4108NWW ferritin dps family protein FD724_RS17300 ENOG4105CX4 Precorrin-6y C5,15-methyltransferase FD724_RS17310 ENOG41063NY Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FD724_RS17320 ENOG4105DDG Cyanophycinase FD724_RS17325 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) FD724_RS17330 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FD724_RS17340 ENOG4107QRA Extracellular solute-binding protein, family 5 FD724_RS17345 ENOG4105DTC 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase FD724_RS17355 ENOG4105CH7 arginosuccinase FD724_RS17380 ENOG4107ZH9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) FD724_RS17385 ENOG4105CNW domain protein FD724_RS17390 ENOG4105CNW domain protein FD724_RS17400 ENOG4105VFU Rna-binding protein FD724_RS17405 ENOG4108Y85 Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) FD724_RS17410 ENOG4105ENT Efflux transporter rnd family, mfp subunit FD724_RS17425 ENOG4107QPH glycogen) synthase FD724_RS17435 ENOG4105C8Y Acetylornithine aminotransferase FD724_RS17460 ENOG4105BZU Histidine kinase FD724_RS17465 ENOG4105C71 hydrolase family 65, central catalytic FD724_RS17470 ENOG4107STW synthase FD724_RS17495 ENOG4105C9B Cysteine desulfurase FD724_RS17500 ENOG4105CVM Molybdenum cofactor synthesis domain protein FD724_RS17515 ENOG41084GG 50S ribosomal protein L33 FD724_RS17520 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FD724_RS17530 ENOG41084A0 50s ribosomal protein L35 FD724_RS17560 ENOG4105EVY Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity) FD724_RS17570 ENOG41084HI prevent-host-death family FD724_RS17590 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FD724_RS17595 ENOG4105ERG peptidase m48, ste24p FD724_RS17605 ENOG4105DSE periplasmic solute binding protein FD724_RS17640 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) FD724_RS17690 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FD724_RS17695 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) FD724_RS17705 ENOG41065U4 response regulator FD724_RS17770 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FD724_RS17790 ENOG4105CK2 sodium dicarboxylate symporter FD724_RS17805 ENOG4105CNW domain protein FD724_RS17810 ENOG4105CNW domain protein FD724_RS17825 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) FD724_RS17830 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) FD724_RS17835 ENOG4105E3N F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FD724_RS17840 ENOG4105VYJ F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FD724_RS17845 ENOG4105S30 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FD724_RS17850 ENOG4105VH4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FD724_RS17855 ENOG4107SM1 it plays a direct role in the translocation of protons across the membrane (By similarity) FD724_RS17860 ENOG4105PA3 atp synthase FD724_RS17865 ENOG4107SWE Methyltransferase FD724_RS17885 ENOG4105EEK Polypeptide FD724_RS17895 ENOG4105FBM allophycocyanin beta subunit FD724_RS17925 ENOG4105BZU Histidine kinase FD724_RS17990 ENOG41080XM UPF0145 protein FD724_RS18015 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FD724_RS18020 ENOG4105CPJ photosystem II manganese-stabilizing FD724_RS18030 ENOG4108HMN Caspase domain FD724_RS18050 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FD724_RS18055 ENOG4105D7Z glutathione synthase FD724_RS18075 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FD724_RS18090 ENOG4105EMU Dehydrogenase FD724_RS18105 ENOG4105EPH radical SAM domain protein FD724_RS18180 ENOG4108UMS Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity) FD724_RS18185 ENOG4105DKR Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) FD724_RS18230 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS18255 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FD724_RS18260 ENOG4105PWN phosphate abc transporter FD724_RS18265 ENOG4105C8U phosphate abc transporter FD724_RS18270 ENOG4105E2Z phosphate ABC transporter (Permease FD724_RS18295 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FD724_RS18325 ENOG4105BZU Histidine kinase FD724_RS18330 ENOG4108HPG -acetyltransferase FD724_RS18350 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FD724_RS18360 ENOG4107SET aldo keto reductase FD724_RS18380 ENOG4105D9P serine threonine protein kinase FD724_RS18390 ENOG4107UU3 sucrose-phosphate synthase (EC 2.4.1.14) FD724_RS18515 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF FD724_RS18530 ENOG4105RD7 BadF BadG BcrA BcrD FD724_RS18545 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FD724_RS18570 ENOG4107S5T Carbohydrate kinase FD724_RS18595 ENOG4105CYM Glutathione S-transferase FD724_RS18600 ENOG4108VPT UPF0234 protein FD724_RS18650 ENOG4107R4J Chloride channel FD724_RS18680 ENOG4108JQ9 ABC transporter FD724_RS18685 ENOG4105NAE bifunctional deaminase-reductase domain protein FD724_RS18690 ENOG4105K63 Thioredoxin FD724_RS18740 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FD724_RS18750 ENOG4105C5F glutamine synthetase FD724_RS18755 ENOG4108TCG allophycocyanin beta subunit FD724_RS18795 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FD724_RS18800 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FD724_RS18805 ENOG4107Z6A sulfate abc transporter permease FD724_RS18855 ENOG4108W3Y Transcriptional regulator, Crp Fnr family FD724_RS18860 ENOG4105D7W serine acetyltransferase FD724_RS18865 ENOG4107YXA Transcriptional regulator, BadM Rrf2 family FD724_RS18885 ENOG4107TSN permease FD724_RS18905 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) FD724_RS18915 ENOG4105C9X ppx gppa phosphatase FD724_RS18925 ENOG4105F0V Cell wall hydrolase FD724_RS18955 ENOG4105EHV domain protein FD724_RS18970 ENOG410841Q phosphoesterase PA-phosphatase related protein FD724_RS19010 ENOG4108JQC penicillin-binding protein 1A FD724_RS19055 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) FD724_RS19060 ENOG4105GVF (ABC) transporter FD724_RS19065 ENOG4105CGH 5'-nucleotidase FD724_RS19130 ENOG410834F Transcriptional regulator FD724_RS19165 ENOG4105BZ1 (ABC) transporter FD724_RS19170 ENOG4105BZ1 (ABC) transporter FD724_RS19195 ENOG4106I2R Coenzyme F420 hydrogenase dehydrogenase, beta FD724_RS19215 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FD724_RS19220 ENOG4105CD2 stage iii sporulation protein aa FD724_RS19240 ENOG4105BZU Histidine kinase FD724_RS19245 ENOG4105BZU Histidine kinase FD724_RS19255 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS19260 ENOG4105BZU Histidine kinase FD724_RS19265 ENOG4105BZU Histidine kinase FD724_RS19280 ENOG4105CD3 dihydroorotase FD724_RS19290 ENOG4105K8N protein family UPF0079, ATPase FD724_RS19295 ENOG4105CHW UPF0052 protein FD724_RS19300 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) FD724_RS19310 ENOG4105DMW Dehydrogenase reductase FD724_RS19315 ENOG4105D2H Uronic isomerase FD724_RS19320 ENOG4105ETE Transcriptional regulator (LacI family FD724_RS19325 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FD724_RS19340 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FD724_RS19345 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FD724_RS19355 ENOG4105CNN ABC, transporter FD724_RS19365 ENOG4105D9R oxidoreductase FD724_RS19390 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS19400 ENOG4108UV1 cellular component movement FD724_RS19425 ENOG4107WDG serine threonine protein kinase FD724_RS19450 ENOG4105CA3 membrane-bound lytic murein transglycosylase FD724_RS19465 ENOG4106WR0 acetolactate synthase (large subunit) FD724_RS19470 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FD724_RS19475 ENOG4105KUU lipolytic protein G-D-S-L family FD724_RS19480 ENOG4105CNF WD-40 repeat protein FD724_RS19495 ENOG4105C26 Dehydrogenase FD724_RS19510 ENOG41078GB pbs lyase FD724_RS19515 ENOG4107SC0 ferredoxin--NADP reductase FD724_RS19520 ENOG4108MZQ phycobilisome linker polypeptide FD724_RS19550 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FD724_RS19575 ENOG4105BZU Histidine kinase FD724_RS19580 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS19590 ENOG4105KHC sulfurtransferase FD724_RS19600 ENOG4105CE4 GlcNAc 6-P deacetylase FD724_RS19615 ENOG4105E7A Glutamine amidotransferase FD724_RS19620 ENOG4105DX0 Hemolysin A FD724_RS19630 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FD724_RS19655 ENOG4108XAN ABC transporter FD724_RS19660 ENOG4105DIK (ABC) transporter FD724_RS19665 ENOG4105CC5 ABC transporter FD724_RS19670 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FD724_RS19695 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FD724_RS19730 ENOG4105C0P Mg chelatase subunit ChlI FD724_RS19740 ENOG4105C5I Dehydrogenase FD724_RS19755 ENOG4105Q36 FHA domain containing protein FD724_RS19760 ENOG4108Q79 6-phosphogluconolactonase (EC 3.1.1.31) FD724_RS19765 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) FD724_RS19770 ENOG4106QP8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) FD724_RS19780 ENOG4105DHP deoxycytidine triphosphate deaminase FD724_RS19790 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) FD724_RS19815 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FD724_RS19825 ENOG4105PW4 Sugar fermentation stimulation protein homolog FD724_RS19850 ENOG4105ECR NmrA family FD724_RS19855 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) FD724_RS19895 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) FD724_RS19900 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS19940 ENOG4107SKI cobyrinic Acid a,c-diamide synthase FD724_RS19945 ENOG4105JZI cytochrome P450 FD724_RS19955 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) FD724_RS19965 ENOG4105BZ1 (ABC) transporter FD724_RS19970 ENOG4105CHH sulfate transporter FD724_RS19980 ENOG4108RVA ribokinase FD724_RS19985 ENOG4105CHF Glutathione S-transferase FD724_RS19990 ENOG4108Q6X Aspartoacylase (EC 3.5.1.15) FD724_RS20005 ENOG4105CFG Acts as a chaperone (By similarity) FD724_RS20050 ENOG4105DXN mazG family FD724_RS20055 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FD724_RS20080 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) FD724_RS20085 ENOG4105CPQ Dehydrogenase FD724_RS20120 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase FD724_RS20130 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FD724_RS20150 ENOG4108DJF Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FD724_RS20170 ENOG4108TQ9 Histidine kinase FD724_RS20190 ENOG4105BZU Histidine kinase FD724_RS20200 ENOG4105BZU Histidine kinase FD724_RS20220 ENOG4105C1J atp-dependent rna helicase FD724_RS20225 ENOG4105NAN IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FD724_RS20245 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FD724_RS20250 ENOG4105CNF WD-40 repeat protein FD724_RS20275 ENOG4105PNM synthesis protein FD724_RS20280 ENOG4105BZU Histidine kinase FD724_RS20285 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS20290 ENOG4105D9P serine threonine protein kinase FD724_RS20295 ENOG4107WDG serine threonine protein kinase FD724_RS20335 ENOG4105D0M Protease HtpX homolog FD724_RS20360 ENOG4107QSS Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity) FD724_RS20375 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FD724_RS20410 ENOG41067HS methyltransferase FD724_RS20415 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FD724_RS20425 ENOG4105C0D helicase FD724_RS20430 ENOG4107XWB Zinc finger, swim domain protein FD724_RS20445 ENOG4105E9X Photosystem II 44 kDa subunit reaction center protein FD724_RS20450 ENOG4105D6H One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity) FD724_RS20455 ENOG4108S5W Seems to be required for the assembly of the photosystem I complex (By similarity) FD724_RS20465 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FD724_RS20470 ENOG4105D82 Glutamate dehydrogenase FD724_RS20480 ENOG4105H0Z Hemerythrin HHE cation binding domain protein FD724_RS20505 ENOG4107XW6 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) FD724_RS20515 ENOG41083CN Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) FD724_RS20540 ENOG4107SK7 Sarcosine-dimethylglycine methyltransferase FD724_RS20550 ENOG4108IJ6 ABC transporter FD724_RS20565 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS20585 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein FD724_RS20615 ENOG4108KQJ Type 11 methyltransferase FD724_RS20625 ENOG41090MY MarR family Transcriptional regulator FD724_RS20670 ENOG4107S2Z UPF0761 membrane protein FD724_RS20700 ENOG4105D65 subunit l FD724_RS20710 ENOG4105C8S subunit m FD724_RS20725 ENOG4105BZU Histidine kinase FD724_RS20730 ENOG4105K64 Glycosyl transferase, family 2 FD724_RS20760 ENOG4107RA4 Glycosyl transferase (Group 1 FD724_RS20775 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase FD724_RS20805 ENOG4107EEY synthase FD724_RS20815 ENOG4105CEY Amp-dependent synthetase and ligase FD724_RS20845 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) FD724_RS20875 ENOG4108NH8 Cation transport protein FD724_RS20885 ENOG4105EMU Dehydrogenase FD724_RS20910 ENOG4105K64 Glycosyl transferase, family 2 FD724_RS20940 ENOG4108IJ6 ABC transporter FD724_RS20955 ENOG4105IQ5 FAD linked oxidase domain protein FD724_RS20980 ENOG4105EPC oxidoreductase FD724_RS21010 ENOG41084GC stage II sporulation protein FD724_RS21015 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FD724_RS21030 ENOG4105D0M Protease HtpX homolog FD724_RS21035 ENOG4108V0P LemA family FD724_RS21045 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) FD724_RS21070 ENOG4105C01 Dihydroxy-acid dehydratase FD724_RS21080 ENOG4105CP9 extracellular ligand-binding receptor FD724_RS21085 ENOG4105D9P serine threonine protein kinase FD724_RS21100 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FD724_RS21130 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) FD724_RS21140 ENOG4108RJ7 Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity) FD724_RS21150 ENOG4105BZU Histidine kinase FD724_RS21200 ENOG4105JZI cytochrome P450 FD724_RS21205 ENOG4105JZI cytochrome P450 FD724_RS21225 ENOG4108IAJ Nad-dependent epimerase dehydratase FD724_RS21235 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor FD724_RS21240 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) FD724_RS21245 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) FD724_RS21280 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) FD724_RS21335 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) FD724_RS21340 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) FD724_RS21370 ENOG4108REV C-phycoerythrin class I alpha chain FD724_RS21375 ENOG4108RIN C-phycoerythrin class I beta chain FD724_RS21385 ENOG4108P5B Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) FD724_RS21395 ENOG4106BTU phycobilisome rod-core linker polypeptide FD724_RS21430 ENOG4105MN0 PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6 FD724_RS21435 ENOG4105F37 PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6 FD724_RS21470 ENOG4105BZU Histidine kinase FD724_RS21485 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FD724_RS21490 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS21495 ENOG4107QPV Serine Threonine protein kinase FD724_RS21500 ENOG4105JZI cytochrome P450 FD724_RS21505 ENOG4108X7A Terpene synthase metal-binding domain-containing protein FD724_RS21510 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS21520 ENOG4105BZU Histidine kinase FD724_RS21525 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FD724_RS21545 ENOG4105CKI cobalamin synthesis protein FD724_RS21570 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) FD724_RS21580 ENOG4105D52 delta-aminolevulinic acid dehydratase FD724_RS21615 ENOG4108JIS Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FD724_RS21630 ENOG4105BZU Histidine kinase FD724_RS21670 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FD724_RS21680 ENOG4106AST May help in the organization of the PsaE and PsaF subunits (By similarity) FD724_RS21685 ENOG4108W6I photosystem I reaction center protein subunit XI FD724_RS21695 ENOG4105KC4 UPF0296 protein FD724_RS21705 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) FD724_RS21710 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FD724_RS21715 ENOG4105BZ4 penicillin-binding protein FD724_RS21760 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FD724_RS21770 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) FD724_RS21775 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) FD724_RS21780 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FD724_RS21785 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FD724_RS21790 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) FD724_RS21795 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FD724_RS21800 ENOG4105CQC Prephenate dehydratase FD724_RS21805 ENOG4108XAD Protein of unknown function (DUF1997) FD724_RS21810 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FD724_RS21845 ENOG4105J3Z Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) FD724_RS21855 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FD724_RS21870 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS21900 ENOG4105EEX Two component transcriptional regulator (Winged helix family FD724_RS21930 ENOG4108Z6B deaminase FD724_RS21950 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) FD724_RS21960 ENOG4105CVA phosphate FD724_RS21965 ENOG4105C0Z ABC transporter FD724_RS21970 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FD724_RS21985 ENOG4105C89 phosphohexose isomerase FD724_RS22025 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FD724_RS22030 ENOG4105X1F electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity) FD724_RS22035 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) FD724_RS22040 ENOG4105WN2 Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity) FD724_RS22055 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) FD724_RS22065 ENOG4105EPU Molybdenum cofactor synthesis domain protein FD724_RS22070 ENOG4105MSA Photosystem II reaction center W protein FD724_RS22080 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FD724_RS22085 ENOG4105CP7 Triose-phosphate isomerase FD724_RS22110 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) FD724_RS22115 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FD724_RS22120 ENOG4105WIA photosystem II reaction center protein H FD724_RS22125 ENOG410686T photosystem II reaction center protein N FD724_RS22210 ENOG4105MXK Carbon dioxide concentrating mechanism protein FD724_RS22215 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml FD724_RS22220 ENOG4108WT6 Carbon dioxide concentrating mechanism protein FD724_RS22230 ENOG4105D65 subunit l FD724_RS22305 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A FD724_RS22335 ENOG4107Z6I Thiamine biosynthesis protein FD724_RS22450 ENOG4105CA3 membrane-bound lytic murein transglycosylase FD724_RS22470 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FD724_RS22475 ENOG4107WDG serine threonine protein kinase FD724_RS22480 ENOG4105C1B dTDP-glucose 4-6-dehydratase FD724_RS22490 ENOG4108TNP FD724_RS22510 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) FD724_RS22520 ENOG4108VIA integral membrane protein FD724_RS22575 ENOG4105D6A Electron transport complex FD724_RS22595 ENOG4105D7K pfkb domain protein FD724_RS22615 ENOG4108PWY Carbohydrate-selective porin OprB FD724_RS22620 ENOG4108W3Y Transcriptional regulator, Crp Fnr family FD724_RS22640 ENOG4105EB3 Histidine kinase FD724_RS22645 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS22660 ENOG4105BZU Histidine kinase FD724_RS22735 ENOG4108VFZ ribulose bisphosphate carboxylase, small FD724_RS22745 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate FD724_RS22780 ENOG410906A Beta-Ig-H3 fasciclin FD724_RS22790 ENOG41068WN FD724_RS22815 ENOG4105BZU Histidine kinase FD724_RS22820 ENOG4105D5K Hemolysin activator protein FD724_RS22845 ENOG41077A9 carbonic anhydrase FD724_RS22865 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) FD724_RS22875 ENOG4105K4I Scp-like extracellular FD724_RS22885 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) FD724_RS22890 ENOG4105WZW rhodanese family FD724_RS22900 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS22930 ENOG4105VUH addiction module killer protein FD724_RS22935 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) FD724_RS22950 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FD724_RS22955 ENOG4105ETX regulatoR FD724_RS22985 ENOG4105C8T Leucyl-tRNA synthetase FD724_RS23000 ENOG4105EMN RNA polymerase sigma factor FD724_RS23010 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FD724_RS23025 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FD724_RS23045 ENOG4108K8S endonuclease I FD724_RS23050 ENOG4105BZ1 (ABC) transporter FD724_RS23060 ENOG4105CMR udp-glucose 4-epimerase FD724_RS23070 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) FD724_RS23090 ENOG4105BZU Histidine kinase FD724_RS23095 ENOG4107VAM peptidase, m28 FD724_RS23135 ENOG4105D7V transposase FD724_RS23150 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FD724_RS23155 ENOG4105BZU Histidine kinase FD724_RS23185 ENOG4105CND Glycosyl transferase, family 2 FD724_RS23190 ENOG4105C6E dna polymerase iii FD724_RS23190 ENOG4105C6E dna polymerase iii FD724_RS23250 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) FD724_RS23255 ENOG4105C8U phosphate abc transporter FD724_RS23260 ENOG4105E2Z phosphate ABC transporter (Permease FD724_RS23280 ENOG4105EMU Dehydrogenase FD724_RS23300 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS23320 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FD724_RS23330 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase FD724_RS23360 ENOG4105WVZ Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FD724_RS23370 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase FD724_RS23405 ENOG4105DRR Transcriptional regulator, GntR family FD724_RS23415 ENOG41087WU FD724_RS23420 ENOG4108ZAF Molybdopterin FD724_RS23435 ENOG410902K Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) FD724_RS23455 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FD724_RS23465 ENOG4105D9P serine threonine protein kinase FD724_RS23475 ENOG4105C1V Peptidase, M16 FD724_RS23480 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FD724_RS23485 ENOG41082T9 Membrane FD724_RS23535 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) FD724_RS23555 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FD724_RS23625 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) FD724_RS23635 ENOG41082AF Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) FD724_RS23645 ENOG4105DZP Membrane-associated zinc metalloprotease FD724_RS23650 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) FD724_RS23690 ENOG4107RNI Glucose 6-phosphate dehydrogenase effector OpcA FD724_RS23695 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FD724_RS23700 ENOG4107QQX Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FD724_RS23705 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 FD724_RS23735 ENOG41081F0 Precorrin-8x methylmutase FD724_RS23740 ENOG4105C59 p-type ATPase FD724_RS23760 ENOG4106CD9 glycosyl transferase group 1 FD724_RS23770 ENOG4105C38 Glycyl-tRNA synthetase beta subunit FD724_RS23775 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FD724_RS23785 ENOG4105C75 arginyL-tRNA synthetase FD724_RS23820 ENOG4105C9B Cysteine desulfurase FD724_RS23835 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS23840 ENOG4105BZU Histidine kinase FD724_RS23860 ENOG4108PJD permease FD724_RS23895 ENOG4105DCF alanine dehydrogenase FD724_RS23940 ENOG4105MKU Transcriptional regulator FD724_RS23955 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FD724_RS23985 ENOG4108UW5 maltose o-acetyltransferase FD724_RS23990 ENOG4105BZU Histidine kinase FD724_RS24000 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) FD724_RS24030 ENOG4108IPT Naphthoate synthase FD724_RS24060 ENOG4105N6Y Thioredoxin FD724_RS24065 ENOG4105CHM Aminotransferase FD724_RS24080 ENOG4108UXN response regulator FD724_RS24090 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FD724_RS24105 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs FD724_RS24120 ENOG4105CIA precorrin-4 C(11)-methyltransferase FD724_RS24130 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) FD724_RS24135 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) FD724_RS24160 ENOG4105CKI cobalamin synthesis protein FD724_RS24180 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) FD724_RS24185 ENOG410823V Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FD724_RS24200 ENOG4105KAN Probably a ribosomal protein or a ribosome-associated protein (By similarity) FD724_RS24215 ENOG4105JZI cytochrome P450 FD724_RS24225 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) FD724_RS24275 ENOG4108IUS Transketolase FD724_RS24280 ENOG4105E98 transcriptional regulator DeoR family FD724_RS24295 ENOG4108USA electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity) FD724_RS24305 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) FD724_RS24310 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FD724_RS24315 ENOG4105KZR One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FD724_RS24320 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity FD724_RS24325 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FD724_RS24330 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FD724_RS24335 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FD724_RS24340 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FD724_RS24345 ENOG410848H 50s ribosomal protein l29 FD724_RS24355 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) FD724_RS24360 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FD724_RS24365 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits FD724_RS24370 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FD724_RS24375 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) FD724_RS24380 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FD724_RS24385 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FD724_RS24390 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FD724_RS24395 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FD724_RS24400 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) FD724_RS24405 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FD724_RS24410 ENOG41067V7 50S ribosomal protein L36 FD724_RS24415 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FD724_RS24420 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FD724_RS24430 ENOG4108ZT0 50S ribosomal protein l17 FD724_RS24435 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FD724_RS24445 ENOG4108UJD 30S ribosomal protein S9 FD724_RS24450 ENOG41082HT Binds the 23S rRNA (By similarity) FD724_RS24455 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) FD724_RS24495 ENOG4105C5H ABC transporter FD724_RS24500 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FD724_RS24515 ENOG4108KMV Glycosyl transferase (Group 1 FD724_RS24525 ENOG4107XHR Involved in DNA repair and RecF pathway recombination (By similarity) FD724_RS24540 ENOG4106CD9 glycosyl transferase group 1 FD724_RS24570 ENOG4105D3Q Sugar transferase FD724_RS24575 ENOG4107WPW Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FD724_RS24590 ENOG4107QXX ABC transporter FD724_RS24595 ENOG4105EZ7 amino acid ABC transporter FD724_RS24600 ENOG4105DRP amino acid AbC transporter FD724_RS24610 ENOG4105CDA abc transporter atp-binding protein FD724_RS24650 ENOG4105C78 Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity) FD724_RS24660 ENOG4105DSM The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity) FD724_RS24680 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FD724_RS24695 ENOG4105VCQ rubredoxin FD724_RS24700 ENOG4105CBX hi0933 family FD724_RS24705 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FD724_RS24740 ENOG4106MP8 UPF0754 membrane protein FD724_RS24745 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) FD724_RS24750 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FD724_RS24760 ENOG4105JD4 ATPase yjob FD724_RS24765 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FD724_RS24775 ENOG4105FFM Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity) FD724_RS24795 ENOG4105C5R Aminotransferase FD724_RS24830 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FD724_RS24835 ENOG4105CJN penicillin-binding protein FD724_RS24840 ENOG4105CJN penicillin-binding protein FD724_RS24855 ENOG41072GX Peptidase M22 Glycoprotease FD724_RS24890 ENOG4105DWF phosphomethylpyrimidine kinase FD724_RS24900 ENOG4108YZA Nitrogen regulatory protein pii FD724_RS24905 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FD724_RS24940 ENOG4107T5V SNARE associated Golgi FD724_RS24950 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) FD724_RS24955 ENOG4105C37 (CBS) domain FD724_RS24975 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FD724_RS24985 ENOG4105DBV ornithine carbamoyltransferase FD724_RS25050 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FD724_RS25065 ENOG4105EYM Major Facilitator superfamily FD724_RS25080 ENOG4105HNP -acetyltransferase FD724_RS25090 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FD724_RS25105 ENOG4105BZU Histidine kinase FD724_RS25125 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FD724_RS25140 ENOG4108IYU L-aspartate oxidase FD724_RS25155 ENOG4105BZU Histidine kinase FD724_RS25160 ENOG4105CVB Vitamin K epoxide reductase FD724_RS25170 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) FD724_RS25220 ENOG4105SS7 PucC protein FD724_RS25225 ENOG4105ECY inositol monophosphatase FD724_RS25245 ENOG4105DB3 bacteriochlorophyll chlorophyll a synthase FD724_RS25260 ENOG4105D0U Arsenite-activated ATPase (ArsA) FD724_RS25275 ENOG4105EY8 ABC transporter FD724_RS25280 ENOG4108KQJ Type 11 methyltransferase FD724_RS25295 ENOG4105CKK Glycosyl transferase, family 2 FD724_RS25300 ENOG4108IAJ Nad-dependent epimerase dehydratase FD724_RS25335 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS25340 ENOG4107V9E glucose-1-phosphate thymidylyltransferase FD724_RS25345 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FD724_RS25350 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FD724_RS25355 ENOG4108N5B 2-phosphosulfolactate phosphatase FD724_RS25380 ENOG4107791 aminotransferase class V FD724_RS25390 ENOG4105M0M Tetracycline resistance protein FD724_RS25395 ENOG4108JJB ABC transporter FD724_RS25400 ENOG4105VUV UPF0367 protein FD724_RS25405 ENOG4105D6H One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity) FD724_RS25410 ENOG4105KZX Pterin carbinolamine dehydratase FD724_RS25415 ENOG4108PWY Carbohydrate-selective porin OprB FD724_RS25425 ENOG4105CV1 Transketolase (EC 2.2.1.1) FD724_RS25440 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FD724_RS25445 ENOG41086B8 CoB-CoM heterodisulfide reductase FD724_RS25515 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) FD724_RS25540 ENOG4108PWY Carbohydrate-selective porin OprB FD724_RS25545 ENOG4105DSE periplasmic solute binding protein FD724_RS25550 ENOG4105FDK ABC transporter FD724_RS25555 ENOG4105FAV ABC, transporter FD724_RS25575 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS25580 ENOG4105VGQ Photosystem I subunit X FD724_RS25590 ENOG4105WEF catalase FD724_RS25595 ENOG4105Y3U Transglycosylase-associated protein FD724_RS25605 ENOG4105EWN Heme oxygenase FD724_RS25660 ENOG4105CEY Amp-dependent synthetase and ligase FD724_RS25665 ENOG4105D7N magnesium and cobalt transport protein CorA FD724_RS25680 ENOG4105CFH Aspartokinase FD724_RS25755 ENOG4108Z4T Peptidase M50 FD724_RS25765 ENOG4107QN1 sodium solute FD724_RS25770 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein FD724_RS25775 ENOG4105C32 Amino acid ABC transporter (Permease) FD724_RS25785 ENOG4105C0Z ABC transporter FD724_RS25795 ENOG4108IV0 ABC, transporter FD724_RS25815 ENOG4105DQR SNARE associated Golgi FD724_RS25835 ENOG4105C7K acetolactate synthase FD724_RS25845 ENOG4105F8J Adenylate Guanylate cyclase FD724_RS25855 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FD724_RS25865 ENOG4105CMV Succinyl-CoA synthetase subunit beta FD724_RS25885 ENOG4105CJW magnesium transporter FD724_RS25955 ENOG4108R9R May be involved in photosynthetic membrane biogenesis (By similarity) FD724_RS25960 ENOG4108YH8 Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) FD724_RS25970 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) FD724_RS25985 ENOG4105CNI cell division protein FtsW FD724_RS26005 ENOG4108IAJ Nad-dependent epimerase dehydratase FD724_RS26010 ENOG4105C6Y Udp-glucose 6-dehydrogenase FD724_RS26045 ENOG4105CEV competence damage-inducible protein FD724_RS26050 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FD724_RS26075 ENOG4108ZGN Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity) FD724_RS26080 ENOG4105CZX twitching motility protein FD724_RS26090 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FD724_RS26120 ENOG4105CPC Aldo Keto reductase FD724_RS26130 ENOG4108RXX maleylacetoacetate isomerase FD724_RS26135 ENOG4105CPQ Dehydrogenase FD724_RS26215 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FD724_RS26235 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FD724_RS26240 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FD724_RS26260 ENOG4105YVZ photosystem II FD724_RS26270 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FD724_RS26300 ENOG4107SDT Homocitrate synthase FD724_RS26330 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FD724_RS26335 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FD724_RS26345 ENOG4105C0W non-ribosomal peptide synthetase FD724_RS26370 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FD724_RS26395 ENOG4105D3Q Sugar transferase FD724_RS26410 ENOG4107XU6 Glycosyl transferase (Group 1 FD724_RS26440 ENOG4108QV3 biosynthesis protein FD724_RS26465 ENOG4105TNG K13735 adhesin invasin FD724_RS26480 ENOG4105EY8 ABC transporter FD724_RS26495 ENOG4107SET aldo keto reductase FD724_RS26510 ENOG4105CPK Glycosyl transferase (Group 1 FD724_RS26530 ENOG4105K64 Glycosyl transferase, family 2 FD724_RS26540 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS26565 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS26570 ENOG4105CAQ asparagine synthetase FD724_RS26575 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS26580 ENOG4106WTF Glycosyl transferase, family 2 FD724_RS26605 ENOG4105K64 Glycosyl transferase, family 2 FD724_RS26620 ENOG4107QN2 dihydrolipoyl dehydrogenase FD724_RS26635 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FD724_RS26655 ENOG4105DHM ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity) FD724_RS26680 ENOG4105C9M aspartyl-trna synthetase FD724_RS26740 ENOG4105E2K Glycosyl transferase (Group 1 FD724_RS26745 ENOG4105E2K Glycosyl transferase (Group 1 FD724_RS26785 ENOG4105C12 Phosphoribosylglycinamide synthetase FD724_RS26815 ENOG4107QRT dEAD DEAH box helicase FD724_RS26820 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein FD724_RS26830 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS26835 ENOG4105D3Q Sugar transferase FD724_RS26840 ENOG4105C0K Gdp-mannose 4,6-dehydratase FD724_RS26850 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FD724_RS26860 ENOG4105DRS transport system, permease FD724_RS26865 ENOG4105D3Q Sugar transferase FD724_RS26875 ENOG4105DS0 Transcriptional regulator, Crp Fnr family FD724_RS26885 ENOG4108K7V UPF0284 protein FD724_RS26910 ENOG4105CFP Peptidase U32 FD724_RS26930 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FD724_RS26935 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) FD724_RS26945 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FD724_RS26995 ENOG4105C42 Type I secretion membrane fusion protein (HlyD FD724_RS27010 ENOG41081AP Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FD724_RS27015 ENOG4108PPB Seems to be required for the assembly of the photosystem I complex (By similarity) FD724_RS27020 ENOG4108RAV Conserved protein FD724_RS27025 ENOG4108RXX maleylacetoacetate isomerase FD724_RS27030 ENOG41063C6 UPF0235 protein FD724_RS27055 ENOG4105BZU Histidine kinase FD724_RS27090 ENOG4107Z5C methylesterase FD724_RS27125 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FD724_RS27190 ENOG4105BZU Histidine kinase FD724_RS27195 ENOG4105BZU Histidine kinase FD724_RS27205 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FD724_RS27210 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) FD724_RS27225 ENOG4105D9P serine threonine protein kinase FD724_RS27255 ENOG4105DFS Conserved Protein FD724_RS27295 ENOG4105DYN CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) FD724_RS27300 ENOG4105DYN CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) FD724_RS27305 ENOG4105KCF CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity) FD724_RS27310 ENOG4105BZU Histidine kinase FD724_RS27320 ENOG4105CTK cobaltochelatase, cobn subunit FD724_RS27325 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FD724_RS27330 ENOG4105CHR reductase FD724_RS27335 ENOG4105CKD glutathione-regulated potassium-efflux system protein FD724_RS27345 ENOG4105D9P serine threonine protein kinase FD724_RS27390 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FD724_RS27415 ENOG4108IJ8 ABC transporter FD724_RS27445 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A FD724_RS27455 ENOG4105C5H ABC transporter FD724_RS27490 ENOG4105D38 putrescine abc transporter FD724_RS27495 ENOG4105E2K Glycosyl transferase (Group 1 FD724_RS27505 ENOG4107QI6 Cysteine desulfurase FD724_RS27570 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) FD724_RS27575 ENOG4105F0N pyrophosphate phospho-hydrolase FD724_RS27590 ENOG4108IJ0 Aspartate ammonia-lyase FD724_RS27595 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FD724_RS27630 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP FD724_RS27635 ENOG4105ESN nucleotide-binding protein FD724_RS27640 ENOG4105ESN nucleotide-binding protein FD724_RS27645 ENOG4105IK6 Terpene synthase metal-binding domain-containing protein FD724_RS27695 ENOG4108J01 L-aspartate oxidase FD724_RS27860 ENOG4105ES5 Histidine kinase FD724_RS27875 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) FD724_RS27900 ENOG4105H0N Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I FD724_RS27905 ENOG4108UQX Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity) FD724_RS27915 ENOG4105DRS transport system, permease FD724_RS27950 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) FD724_RS27965 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FD724_RS28000 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FD724_RS28020 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FD724_RS28035 ENOG4105CD8 aminopeptidase N FD724_RS28075 ENOG4105W2C Glycosyl transferase FD724_RS28080 ENOG4105BZ1 (ABC) transporter FD724_RS28095 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FD724_RS28100 ENOG4105K9Q Binds to the 23S rRNA (By similarity) FD724_RS28105 ENOG4105CDU Replicative dna helicase FD724_RS28105 ENOG4105CDU Replicative dna helicase FD724_RS28110 ENOG4108V1T peptidylprolyl cis-trans isomerase FD724_RS28195 ENOG4107TIF Phenazine biosynthesis protein, PhzF family FD724_RS28205 ENOG4107RAQ aminopeptidase FD724_RS28230 ENOG41082B1 30S ribosomal protein S16 FD724_RS28235 ENOG4105VB6 UPF0109 protein FD724_RS28260 ENOG4105BZ1 (ABC) transporter FD724_RS28305 ENOG4105DGW oligopeptidase A FD724_RS28335 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FD724_RS28345 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) FD724_RS28355 ENOG4105CDA abc transporter atp-binding protein FD724_RS28360 ENOG4107R0W ABC transporter FD724_RS28380 ENOG4108IXY short-chain dehydrogenase reductase FD724_RS28405 ENOG4105EHU Circadian clock protein KaiC FD724_RS28410 ENOG4108ZGN Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity) FD724_RS28415 ENOG4108WXF Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation FD724_RS28420 ENOG4105BZU Histidine kinase FD724_RS28425 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) FD724_RS28470 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) FD724_RS28525 ENOG4105BZU Histidine kinase FD724_RS28530 ENOG41060D5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FD724_RS28535 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FD724_RS28540 ENOG41089N3 Inherit from COG: cobyrinic Acid a,c-diamide synthase FD724_RS28555 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) FD724_RS28595 ENOG4105CKX Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP FD724_RS28610 ENOG4105F8J Adenylate Guanylate cyclase FD724_RS28620 ENOG4107QPR SAICAR synthetase FD724_RS28625 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FD724_RS28630 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FD724_RS28635 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) FD724_RS28655 ENOG4105CPC Aldo Keto reductase FD724_RS28675 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) FD724_RS28690 ENOG4105CTK cobaltochelatase, cobn subunit FD724_RS28750 ENOG4105C8Y Acetylornithine aminotransferase FD724_RS28770 ENOG4108062 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FD724_RS28780 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FD724_RS28785 ENOG4105BZU Histidine kinase FD724_RS28810 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FD724_RS28815 ENOG4105VFU Rna-binding protein FD724_RS28830 ENOG4108UK5 Transposase FD724_RS28860 ENOG4105E6M Sulphatase-modifying factor protein FD724_RS28865 ENOG4105ENH Sulfatase FD724_RS28905 ENOG4105DHJ ABC, transporter FD724_RS28920 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FD724_RS28925 ENOG4105BZU Histidine kinase FD724_RS28930 ENOG4107QPD alcohol dehydrogenase FD724_RS28935 ENOG4105JKW Valine--pyruvate aminotransferase FD724_RS28940 ENOG41080P6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) FD724_RS28950 ENOG4107QRI Phosphoketolase FD724_RS28955 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) FD724_RS28960 ENOG4105EM2 membrane FD724_RS28970 ENOG4105C4W S-formylglutathione hydrolase FD724_RS28975 ENOG4105EYW Ion transport protein FD724_RS28980 ENOG4108Z6B deaminase FD724_RS29015 ENOG4107YU2 histidine triad (hIT) protein FD724_RS29035 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS29040 ENOG4105BZU Histidine kinase FD724_RS29045 ENOG4105EMU Dehydrogenase FD724_RS29055 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FD724_RS29065 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS29070 ENOG4105BZU Histidine kinase FD724_RS29090 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FD724_RS29105 ENOG4105CIK Amidinotransferase FD724_RS29120 ENOG4105D9N nucleoside FD724_RS29130 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) FD724_RS29150 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FD724_RS29160 ENOG4108IAJ Nad-dependent epimerase dehydratase FD724_RS29195 ENOG4105BZU Histidine kinase FD724_RS29205 ENOG4105C59 p-type ATPase FD724_RS29220 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS29230 ENOG4105BZU Histidine kinase FD724_RS29240 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS29250 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FD724_RS29255 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FD724_RS29300 ENOG4105FJR Lmbe family FD724_RS29320 ENOG410600T transposase FD724_RS29345 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FD724_RS29355 ENOG4105BZU Histidine kinase FD724_RS29360 ENOG4107QJE Chromosome Partitioning Protein FD724_RS29365 ENOG4105E0R Deoxyhypusine synthase FD724_RS29380 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family FD724_RS29400 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS29420 ENOG4108SHN Glycosyl transferase, family 2 FD724_RS29425 ENOG4107YJ4 chain length determinant protein FD724_RS29440 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FD724_RS29470 ENOG4105BZU Histidine kinase FD724_RS29480 ENOG4107R8N Glycosyl transferase, family 2 FD724_RS29495 ENOG4105BZ1 (ABC) transporter FD724_RS29500 ENOG4105BZ1 (ABC) transporter FD724_RS29515 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FD724_RS29520 ENOG4105C7K acetolactate synthase FD724_RS29530 ENOG4105CEY Amp-dependent synthetase and ligase FD724_RS29565 ENOG4105D5K Hemolysin activator protein FD724_RS29585 ENOG4105GHY electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity) FD724_RS29625 ENOG4107RNU major facilitator superfamily MFS_1 FD724_RS29640 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FD724_RS29650 ENOG4106HX1 Uncharacterised protein family (UPF0150) FD724_RS29655 ENOG4105F04 LysR family Transcriptional regulator FD724_RS29665 ENOG4108KGH TRANSCRIPTIONal FD724_RS29725 ENOG410600T transposase FD724_RS29745 ENOG41083MR nifu domain-containing protein FD724_RS29750 ENOG4105BZU Histidine kinase FD724_RS29760 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) FD724_RS29790 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FD724_RS29800 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FD724_RS29805 ENOG4105C6X Major Facilitator FD724_RS29870 ENOG4105EYH Exonuclease FD724_RS29875 ENOG4108E1C hydrolase FD724_RS29885 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FD724_RS29910 ENOG4107RIX inner membrane protein translocase component YidC FD724_RS29925 ENOG4107ETG 50S ribosomal protein L34 FD724_RS29940 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FD724_RS29945 ENOG4105W8H transhydrogenase (subunit alpha FD724_RS29950 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FD724_RS29970 ENOG4105BZU Histidine kinase FD724_RS29985 ENOG4105BZU Histidine kinase FD724_RS29990 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS30000 ENOG410600T transposase FD724_RS30035 ENOG4107R7I amino acid FD724_RS30045 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FD724_RS30070 ENOG4105DJZ UPF0182 protein FD724_RS30090 ENOG4105JNK Glycosyl transferase (Group 1 FD724_RS30100 ENOG4105D1U peptidase U62 modulator of DNA gyrase FD724_RS30115 ENOG4105CSV Glutaminase FD724_RS30140 ENOG4105EHG Permease protein FD724_RS30145 ENOG4105KPY Small multidrug resistance protein FD724_RS30150 ENOG4105VN1 Heat shock protein FD724_RS30165 ENOG4105IB0 filamentous hemagglutinin family outer membrane protein FD724_RS30250 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) FD724_RS30305 ENOG4105BZU Histidine kinase FD724_RS30310 ENOG4108JQB penicillin-binding protein 1C FD724_RS30315 ENOG4105DN3 alpha-2-macroglobulin domain protein FD724_RS30335 ENOG4105BZU Histidine kinase FD724_RS30340 ENOG4105CX4 Precorrin-6y C5,15-methyltransferase FD724_RS30345 ENOG4107RAJ Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) FD724_RS30355 ENOG4105BZU Histidine kinase FD724_RS30365 ENOG4105KK4 UPF0060 membrane protein FD724_RS30370 ENOG4105BZU Histidine kinase FD724_RS30460 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FD724_RS30485 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FD724_RS30490 ENOG41082AN stage II sporulation protein FD724_RS30510 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) FD724_RS30525 ENOG4105BZU Histidine kinase FD724_RS30535 ENOG4105BZU Histidine kinase FD724_RS30540 ENOG4106A2Z transcriptional regulator antitoxin, MazE FD724_RS30555 ENOG4105QYV Membrane FD724_RS30560 ENOG4105CA0 peroxidase FD724_RS30565 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FD724_RS30580 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FD724_RS30610 ENOG4105D05 Receptor FD724_RS30630 ENOG4105D9P serine threonine protein kinase FD724_RS30635 ENOG4108IV0 ABC, transporter FD724_RS30640 ENOG4108M11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FD724_RS30645 ENOG410811H Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) FD724_RS30680 ENOG4108P5B Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) FD724_RS30745 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FD724_RS30765 ENOG4105BZU Histidine kinase FD724_RS30775 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FD724_RS30785 ENOG4105DGI Alkaline phosphatase FD724_RS30800 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase FD724_RS30810 ENOG4105F8J Adenylate Guanylate cyclase FD724_RS30830 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FD724_RS30840 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FD724_RS30850 ENOG4105EMU Dehydrogenase FD724_RS30855 ENOG4105CF7 AraC family transcriptional regulator FD724_RS30860 ENOG4105NTW Transcriptional regulator FD724_RS30870 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) FD724_RS30885 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FD724_RS30910 ENOG4108JA1 polyketide synthase FD724_RS30920 ENOG4107QKG PfaD family FD724_RS30935 ENOG4107P5I polyketide synthase FD724_RS30960 ENOG4105BZU Histidine kinase FD724_RS30965 ENOG4105BZU Histidine kinase FD724_RS30970 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FD724_RS30985 ENOG4105BZU Histidine kinase FD724_RS30995 ENOG4107RDP Dehydrogenase FD724_RS31020 ENOG4106CD9 glycosyl transferase group 1 FD724_RS31025 ENOG4105EHE chorismate mutase- prephenate dehydrogenase FD724_RS31035 ENOG4105D49 3-dehydroquinate synthase FD724_RS31040 ENOG4105CRQ synthase (Component I) FD724_RS31060 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FD724_RS31065 ENOG4108I0Q anthranilate phosphoribosyltransferase FD724_RS31070 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase FD724_RS31085 ENOG4108W6C Dehydrogenase FD724_RS31100 ENOG4107WDG serine threonine protein kinase FD724_RS31110 ENOG4107R4J Chloride channel FD724_RS31130 ENOG4108RPX mosc domain containing protein FD724_RS31155 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) FD724_RS31165 ENOG4105DVW rieske (2Fe-2S) FD724_RS31175 ENOG4105BZU Histidine kinase FD724_RS31205 ENOG4108I5U Uridine phosphorylase FD724_RS31210 ENOG4108UVJ appr-1-p processing domain protein FD724_RS31270 ENOG4105F32 YngK protein FD724_RS31280 ENOG4105CHR reductase FD724_RS31285 ENOG4105VCQ rubredoxin FD724_RS31315 ENOG4105I3K Ferric uptake regulator, Fur family FD724_RS31330 ENOG4105C42 Type I secretion membrane fusion protein (HlyD FD724_RS31335 ENOG4108JJA ABC, transporter FD724_RS31355 ENOG4105EXC Acyl-transferase FD724_RS31375 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FD724_RS31415 ENOG4105DTQ mandelate racemase muconate lactonizing FD724_RS31445 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FD724_RS31450 ENOG4107RHB Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity) FD724_RS31505 ENOG41060PQ electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity) FD724_RS31525 ENOG4107WDG serine threonine protein kinase FD724_RS31540 ENOG4105CPF Cell wall formation (By similarity) FD724_RS31550 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FD724_RS31575 ENOG4105K70 DNA-binding protein FD724_RS31820 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FD724_RS31915 ENOG4108W6C Dehydrogenase FD724_RS31985 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) FD724_RS32015 ENOG4107QRP cobalamin biosynthesis protein CobW FD724_RS32040 ENOG4105JFG SpoIID LytB domain protein FD724_RS32075 ENOG4105C7H Helicase, RecD TraA family FD724_RS32080 ENOG4105FA0 parb-like partition protein FD724_RS32085 ENOG4107QJE Chromosome Partitioning Protein FD724_RS32255 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FD724_RS32265 ENOG4105CNF WD-40 repeat protein FD724_RS32290 ENOG41087PP glycosyltransferase MGT family FD724_RS32300 ENOG4105CVB Vitamin K epoxide reductase FD724_RS32395 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FD724_RS32420 ENOG4108RPX mosc domain containing protein FD724_RS32430 ENOG4105CHP RNA polymerase FD724_RS32435 ENOG4105GRZ Ycii-related protein FD724_RS32455 ENOG4108K3A Glutathione S-transferase FD724_RS32560 ENOG4105CDU Replicative dna helicase FD724_RS32585 ENOG4105CDU Replicative dna helicase FD724_RS32680 ENOG4108Z66 YbaK ebsC protein FD724_RS32685 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FD724_RS32760 ENOG4105CYM Glutathione S-transferase FD724_RS32810 ENOG4108I5C dEAD DEAH box helicase FD724_RS32850 ENOG4105C6E dna polymerase iii FD724_RS32875 ENOG4108790 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FD724_RS32905 ENOG4105BZU Histidine kinase FD724_RS32910 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FD724_RS32975 ENOG4105BZU Histidine kinase FD724_RS32980 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS33115 ENOG4107QJE Chromosome Partitioning Protein FD724_RS33160 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FD724_RS33175 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) FD724_RS33180 ENOG4105XRQ Xanthine dehydrogenase accessory factor FD724_RS33185 ENOG4105C7W Xanthine dehydrogenase FD724_RS33190 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding FD724_RS33195 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit FD724_RS33215 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FD724_RS33245 ENOG4105CV8 reductase FD724_RS33260 ENOG4105E2A Dehydrogenase FD724_RS33275 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) FD724_RS33340 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FD724_RS33365 ENOG4108J5G 6-phosphogluconate dehydrogenase FD724_RS33480 ENOG4105D7V transposase FD724_RS33485 ENOG4107U9H DNA polymerase FD724_RS33535 ENOG4105DFS Conserved Protein FD724_RS33545 ENOG41089N3 Inherit from COG: cobyrinic Acid a,c-diamide synthase FD724_RS33580 ENOG410600T transposase FD724_RS33595 ENOG4105ECQ AraC Family Transcriptional Regulator FD724_RS33615 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FD724_RS33625 ENOG4108UXE Protein tyrosine phosphatase FD724_RS33690 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FD724_RS33695 ENOG4108ES9 ParB domain protein nuclease FD724_RS33700 ENOG4107QJE Chromosome Partitioning Protein FD724_RS33705 ENOG4105DFS Conserved Protein FD724_RS33745 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS33820 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS33845 ENOG4105VSH 4-oxalocrotonate tautomerase FD724_RS33850 ENOG4108W9T type 1 fimbriae regulatory protein FD724_RS33990 ENOG4105CFI type iii restriction protein res subunit FD724_RS34010 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS34180 ENOG4105D7T ABC transporter FD724_RS34185 ENOG4105D2X ABC transporter substrate-binding protein FD724_RS34295 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FD724_RS34340 ENOG4105CEY Amp-dependent synthetase and ligase FD724_RS34345 ENOG4105J7D transcriptional regulator FD724_RS34355 ENOG4107RSM transcriptional regulator FD724_RS34370 ENOG4105VUH addiction module killer protein FD724_RS34380 ENOG4105C0D helicase FD724_RS34390 ENOG4107QJE Chromosome Partitioning Protein FD724_RS34395 ENOG4105FA0 parb-like partition protein FD724_RS34405 ENOG4107QPV Serine Threonine protein kinase FD724_RS34410 ENOG4105D9P serine threonine protein kinase FD724_RS34600 ENOG4107QJE Chromosome Partitioning Protein FD724_RS34605 ENOG4105FA0 parb-like partition protein FD724_RS34635 ENOG4105D5K Hemolysin activator protein FD724_RS34665 ENOG4108I7H Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FD724_RS34670 ENOG4105C7H Helicase, RecD TraA family FD724_RS34700 ENOG410600T transposase FD724_RS34770 ENOG4107QJE Chromosome Partitioning Protein FD724_RS34775 ENOG4105FA0 parb-like partition protein FD724_RS34805 ENOG4105C0D helicase FD724_RS34815 ENOG4105D1H recombination factor protein RarA FD724_RS34870 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS34880 ENOG4105CEP NADH dehydrogenase FD724_RS34895 ENOG4105EIE fructose-bisphosphate aldolase FD724_RS34900 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein FD724_RS34910 ENOG4107QN2 dihydrolipoyl dehydrogenase FD724_RS34935 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FD724_RS34950 ENOG4105E1J oxidoreductase FD724_RS34965 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr FD724_RS34995 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) FD724_RS35000 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS35005 ENOG4105ENE Histidine kinase FD724_RS35015 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) FD724_RS35020 ENOG4105WH1 Two component transcriptional regulator luxr family FD724_RS35025 ENOG4105D9P serine threonine protein kinase FD724_RS35125 ENOG4105CDU Replicative dna helicase FD724_RS35130 ENOG4105CDU Replicative dna helicase FD724_RS35195 ENOG4108JJA ABC, transporter FD724_RS35200 ENOG4108JJA ABC, transporter FD724_RS35245 ENOG4107ZBH radical SAM domain protein FD724_RS35265 ENOG4105D1F ATP-binding protein FD724_RS35285 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FD724_RS35290 ENOG4105BZU Histidine kinase FD724_RS35305 ENOG4108TQ9 Histidine kinase FD724_RS35360 ENOG4105D7V transposase FD724_RS35385 ENOG4107QI1 Mate efflux family protein FD724_RS35425 ENOG4105E1F short-chain dehydrogenase reductase FD724_RS35435 ENOG4108JEB The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FD724_RS35450 ENOG4105K70 DNA-binding protein FD724_RS35515 ENOG4108Z66 YbaK ebsC protein FD724_RS35645 ENOG4105D9P serine threonine protein kinase FD724_RS35650 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS35665 ENOG4105FBN Acid phosphatase FD724_RS35720 ENOG4105CP2 von willebrand factor, type a FD724_RS35730 ENOG4105CDU Replicative dna helicase FD724_RS35775 ENOG4105C59 p-type ATPase FD724_RS35835 ENOG4105ETX regulatoR FD724_RS35840 ENOG4105BZU Histidine kinase FD724_RS35845 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FD724_RS35850 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein FD724_RS35885 ENOG41082SX arsR family transcriptional regulator FD724_RS35905 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FD724_RS35945 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction FD724_RS35965 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FD724_RS36070 ENOG4105NPE arsR family transcriptional regulator FD724_RS36160 ENOG4105K70 DNA-binding protein FD724_RS36270 ENOG410600T transposase FD724_RS36300 ENOG4105CHR reductase FD724_RS36415 ENOG4108W6C Dehydrogenase FD724_RS36480 ENOG4105C28 cystathionine FD724_RS36490 ENOG4105CHM Aminotransferase FD724_RS36525 ENOG4105D0B Nitrogenase protein alpha chain FD724_RS36540 ENOG4105D0B Nitrogenase protein alpha chain FD724_RS36545 ENOG4105XEA Tetr family transcriptional regulator FD724_RS36615 ENOG4108DBC nitroreductase FD724_RS36630 ENOG4107S73 homocitrate synthase FD724_RS36655 ENOG4105D0B Nitrogenase protein alpha chain FD724_RS36665 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FD724_RS36675 ENOG4107XWS modD protein FD724_RS36690 ENOG4105X1Q TOBE domain protein FD724_RS36705 ENOG4108PWY Carbohydrate-selective porin OprB FD724_RS36710 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FD724_RS36715 ENOG4108IJ6 ABC transporter FD724_RS36730 ENOG4105DZR Type I site-specific deoxyribonuclease FD724_RS36735 ENOG4105DK8 Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN FD724_RS36740 ENOG4105D0B Nitrogenase protein alpha chain FD724_RS36745 ENOG4105DSM The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity) FD724_RS36750 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FD724_RS36975 ENOG41089N3 Inherit from COG: cobyrinic Acid a,c-diamide synthase FD724_RS37085 ENOG4105C7H Helicase, RecD TraA family FD724_RS37095 ENOG4105C7H Helicase, RecD TraA family FD724_RS37200 ENOG4105C7H Helicase, RecD TraA family FD724_RS37255 ENOG4105CNF WD-40 repeat protein FD724_RS37260 ENOG4108PBA serine threonine protein kinase FD724_RS37290 ENOG4105CVB Vitamin K epoxide reductase FD724_RS37350 ENOG4105EGS Mechanosensitive ion channel FD724_RS37360 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FD724_RS37370 ENOG4105NF4 modulator of drug activity FD724_RS37400 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FD724_RS37425 ENOG4105ENE Histidine kinase FD724_RS37435 ENOG4105K64 Glycosyl transferase, family 2 FD724_RS37470 ENOG4105CDU Replicative dna helicase FD724_RS37470 ENOG4105CDU Replicative dna helicase FD724_RS37795 ENOG4105FA0 parb-like partition protein FD724_RS38030 ENOG4105C4R Atp-dependent dna helicase FD724_RS38095 ENOG41082K6 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FD724_RS38175 ENOG4105C9U ATP-dependent DNA helicase RecQ FD724_RS38360 ENOG4105BZU Histidine kinase FD724_RS38475 ENOG4105EKQ RNA-directed DNA polymerase FD724_RS38565 ENOG4105CNF WD-40 repeat protein FD724_RS38575 ENOG4105N1N Cupin superfamily protein FD724_RS38775 ENOG4105WVZ Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FD724_RS38800 ENOG4105WVZ Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FD724_RS38960 ENOG4108HMN Caspase domain FD724_RS39035 ENOG4107XGZ Hydrolase FD724_RS39055 ENOG4105CNF WD-40 repeat protein FD724_RS39275 ENOG4105FA0 parb-like partition protein FD724_RS39280 ENOG4107QJE Chromosome Partitioning Protein FD724_RS39285 ENOG4105C7H Helicase, RecD TraA family FD724_RS39325 ENOG4105CFI type iii restriction protein res subunit FD724_RS39330 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FD724_RS39340 ENOG4107U7B Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FD724_RS39355 ENOG4105BZU Histidine kinase FD724_RS39505 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) FD724_RS39550 ENOG4105GRZ Ycii-related protein FD724_RS39570 ENOG4108K3A Glutathione S-transferase FD724_RS39610 ENOG4107EMZ glycosyl transferase family FD724_RS39620 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FD724_RS39745 ENOG4105C7H Helicase, RecD TraA family FD724_RS39815 ENOG4108W9T type 1 fimbriae regulatory protein FD724_RS39885 ENOG4105CDU Replicative dna helicase FD724_RS39885 ENOG4105CDU Replicative dna helicase FD724_RS39895 ENOG4108HMN Caspase domain FD724_RS39895 ENOG4108HMN Caspase domain FD724_RS39935 ENOG4105JZI cytochrome P450 FD724_RS40050 ENOG41089N3 Inherit from COG: cobyrinic Acid a,c-diamide synthase FD724_RS40070 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FD724_RS40095 ENOG4105CDU Replicative dna helicase FD724_RS40105 ENOG4105CP2 von willebrand factor, type a FD724_RS40160 ENOG4105BZU Histidine kinase FD724_RS40170 ENOG4108W9T type 1 fimbriae regulatory protein FD724_RS40175 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase