locus-tag	class	description
FD724_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FD724_RS00035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FD724_RS00035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FD724_RS00045	COG0515	serine threonine protein kinase
FD724_RS00045	COG3266	domain, Protein
FD724_RS00075	COG0574	Belongs to the PEP-utilizing enzyme family
FD724_RS00075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FD724_RS00080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FD724_RS00090	COG4251	negative regulation of phosphorylation
FD724_RS00095	COG0784	Response regulator, receiver
FD724_RS00100	COG5002	protein histidine kinase activity
FD724_RS00105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FD724_RS00110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FD724_RS00115	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FD724_RS00130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FD724_RS00140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FD724_RS00150	COG1032	radical SAM domain protein
FD724_RS00155	COG0592	DNA-directed DNA polymerase activity
FD724_RS00160	COG2091	lysine biosynthetic process via aminoadipic acid
FD724_RS00165	COG0300	oxidoreductase activity
FD724_RS00170	COG3320	Male sterility
FD724_RS00170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FD724_RS00175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FD724_RS00175	COG2070	2-Nitropropane dioxygenase
FD724_RS00190	COG3321	synthase
FD724_RS00190	COG0604	alcohol dehydrogenase
FD724_RS00210	COG1216	Glycosyl transferase, family 2
FD724_RS00230	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FD724_RS00260	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FD724_RS00260	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FD724_RS00265	COG1196	nuclear chromosome segregation
FD724_RS00265	COG0741	lytic transglycosylase activity
FD724_RS00265	COG0739	heme binding
FD724_RS00280	COG0667	Aldo Keto reductase
FD724_RS00300	COG1410	methionine synthase
FD724_RS00300	COG0646	methionine synthase
FD724_RS00305	COG0438	transferase activity, transferring glycosyl groups
FD724_RS00325	COG4968	Prepilin-type N-terminal cleavage methylation domain
FD724_RS00330	COG1215	transferase activity, transferring glycosyl groups
FD724_RS00335	COG1215	transferase activity, transferring glycosyl groups
FD724_RS00340	COG1216	Glycosyl transferase, family 2
FD724_RS00340	COG0463	Glycosyl transferase, family 2
FD724_RS00370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FD724_RS00375	COG0552	protein localization to endoplasmic reticulum
FD724_RS00380	COG2208	phosphoserine phosphatase activity
FD724_RS00400	COG0702	epimerase
FD724_RS00410	COG0596	Alpha beta hydrolase
FD724_RS00415	COG1937	Protein conserved in bacteria
FD724_RS00430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FD724_RS00440	COG2267	carboxylic ester hydrolase activity
FD724_RS00455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FD724_RS00465	COG0416	fatty acid biosynthetic process
FD724_RS00470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD724_RS00475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FD724_RS00485	COG2815	serine threonine protein kinase
FD724_RS00485	COG0515	serine threonine protein kinase
FD724_RS00495	COG0628	permease
FD724_RS00505	COG1193	negative regulation of DNA recombination
FD724_RS00540	COG2337	Toxic component of a toxin-antitoxin (TA) module
FD724_RS00570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FD724_RS00575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FD724_RS00580	COG0443	Heat shock 70 kDa protein
FD724_RS00585	COG0484	heat shock protein binding
FD724_RS00595	COG1162	GTPase activity
FD724_RS00605	COG1543	Belongs to the glycosyl hydrolase 57 family
FD724_RS00610	COG3258	Cytochrome c
FD724_RS00615	COG0723	plastoquinol--plastocyanin reductase activity
FD724_RS00625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FD724_RS00630	COG0805	protein transport
FD724_RS00640	COG0300	oxidoreductase activity
FD724_RS00720	COG0484	heat shock protein binding
FD724_RS00725	COG0484	heat shock protein binding
FD724_RS00735	COG1408	metallophosphoesterase
FD724_RS00740	COG1408	metallophosphoesterase
FD724_RS00760	COG2261	transglycosylase associated protein
FD724_RS00765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FD724_RS00770	COG0066	3-isopropylmalate dehydratase activity
FD724_RS00775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FD724_RS00795	COG0768	penicillin binding
FD724_RS00810	COG0584	glycerophosphoryl diester phosphodiesterase
FD724_RS00825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FD724_RS00830	COG2175	clavaminate synthase activity
FD724_RS00845	COG2199	diguanylate cyclase activity
FD724_RS00850	COG0515	serine threonine protein kinase
FD724_RS00855	COG0463	Glycosyl transferase, family 2
FD724_RS00855	COG0457	Tetratricopeptide repeat
FD724_RS00865	COG0436	Aminotransferase
FD724_RS00875	COG1830	Aldolase
FD724_RS00915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FD724_RS00920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FD724_RS00930	COG2198	Histidine kinase
FD724_RS00930	COG5002	protein histidine kinase activity
FD724_RS00930	COG0784	Response regulator, receiver
FD724_RS00945	COG2172	sigma factor antagonist activity
FD724_RS00950	COG1366	Belongs to the anti-sigma-factor antagonist family
FD724_RS00955	COG1366	Belongs to the anti-sigma-factor antagonist family
FD724_RS00980	COG0628	permease
FD724_RS01040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FD724_RS01085	COG1733	regulation of RNA biosynthetic process
FD724_RS01105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS01110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FD724_RS01130	COG0783	Belongs to the Dps family
FD724_RS01135	COG4572	Cation transport regulator
FD724_RS01185	COG3237	CsbD-like
FD724_RS01200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FD724_RS01230	COG0312	modulator of DNA gyrase
FD724_RS01235	COG0724	RNA recognition motif
FD724_RS01240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FD724_RS01250	COG0752	glycyl-tRNA synthetase alpha subunit
FD724_RS01290	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FD724_RS01315	COG3447	MASE1 domain protein
FD724_RS01315	COG5001	Diguanylate cyclase
FD724_RS01315	COG5002	protein histidine kinase activity
FD724_RS01330	COG0640	Transcriptional regulator
FD724_RS01345	COG0745	RESPONSE REGULATOR receiver
FD724_RS01360	COG0784	Response regulator, receiver
FD724_RS01360	COG5002	protein histidine kinase activity
FD724_RS01360	COG2205	protein histidine kinase activity
FD724_RS01375	COG0745	RESPONSE REGULATOR receiver
FD724_RS01380	COG0789	Transcriptional regulator
FD724_RS01400	COG2217	Heavy metal translocating P-type atpase
FD724_RS01410	COG4581	dead DEAH box helicase
FD724_RS01415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FD724_RS01420	COG1799	cell septum assembly
FD724_RS01425	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FD724_RS01435	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FD724_RS01440	COG1160	GTP binding
FD724_RS01445	COG1994	Peptidase M50
FD724_RS01445	COG0517	IMP dehydrogenase activity
FD724_RS01455	COG0135	phosphoribosylanthranilate isomerase activity
FD724_RS01460	COG0302	gtp cyclohydrolase
FD724_RS01465	COG0300	oxidoreductase activity
FD724_RS01470	COG0825	malonyl-CoA metabolic process
FD724_RS01475	COG5322	oxidoreductase activity
FD724_RS01480	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FD724_RS01485	COG0395	ABC-type sugar transport system, permease component
FD724_RS01515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FD724_RS01520	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FD724_RS01555	COG0697	spore germination
FD724_RS01565	COG0306	phosphate transporter
FD724_RS01575	COG1063	alcohol dehydrogenase
FD724_RS01580	COG1247	-acetyltransferase
FD724_RS01630	COG0431	NADPH-dependent FMN reductase
FD724_RS01635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD724_RS01645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD724_RS01665	COG0667	Aldo Keto reductase
FD724_RS01670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS01675	COG1132	(ABC) transporter
FD724_RS01685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS01690	COG0412	Dienelactone hydrolase
FD724_RS01715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD724_RS01725	COG3266	domain, Protein
FD724_RS01725	COG0515	serine threonine protein kinase
FD724_RS01730	COG1215	transferase activity, transferring glycosyl groups
FD724_RS01755	COG2319	Wd-40 repeat
FD724_RS01755	COG4249	Peptidase C14 caspase catalytic subunit p20
FD724_RS01790	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FD724_RS01795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FD724_RS01800	COG0459	protein refolding
FD724_RS01805	COG0598	Magnesium transport protein CorA
FD724_RS01820	COG0571	ribonuclease III activity
FD724_RS01845	COG2205	protein histidine kinase activity
FD724_RS01845	COG0784	Response regulator, receiver
FD724_RS01870	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FD724_RS01875	COG2211	Major facilitator Superfamily
FD724_RS01880	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FD724_RS01895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FD724_RS01910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FD724_RS01935	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FD724_RS01940	COG0415	Belongs to the DNA photolyase family
FD724_RS02005	COG0438	transferase activity, transferring glycosyl groups
FD724_RS02010	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FD724_RS02025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FD724_RS02035	COG0432	Pfam Uncharacterised protein family UPF0047
FD724_RS02045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FD724_RS02065	COG0515	serine threonine protein kinase
FD724_RS02070	COG0515	serine threonine protein kinase
FD724_RS02080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FD724_RS02090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD724_RS02110	COG0006	proline dipeptidase activity
FD724_RS02125	COG0512	Glutamine amidotransferase of anthranilate synthase
FD724_RS02125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FD724_RS02130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FD724_RS02135	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FD724_RS02160	COG0670	Belongs to the BI1 family
FD724_RS02170	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
FD724_RS02170	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
FD724_RS02185	COG0571	ribonuclease III activity
FD724_RS02190	COG0784	Response regulator, receiver
FD724_RS02190	COG2205	protein histidine kinase activity
FD724_RS02195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FD724_RS02215	COG1116	anion transmembrane transporter activity
FD724_RS02225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FD724_RS02230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FD724_RS02235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FD724_RS02255	COG0412	Dienelactone hydrolase
FD724_RS02300	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FD724_RS02305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD724_RS02325	COG3000	fatty acid hydroxylase
FD724_RS02325	COG0300	oxidoreductase activity
FD724_RS02335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FD724_RS02360	COG0668	transmembrane transport
FD724_RS02365	COG4251	negative regulation of phosphorylation
FD724_RS02365	COG3706	GGDEF domain
FD724_RS02365	COG5001	Diguanylate cyclase
FD724_RS02365	COG2203	Gaf domain
FD724_RS02370	COG0438	transferase activity, transferring glycosyl groups
FD724_RS02385	COG0438	transferase activity, transferring glycosyl groups
FD724_RS02390	COG1216	Glycosyl transferase, family 2
FD724_RS02395	COG0438	transferase activity, transferring glycosyl groups
FD724_RS02405	COG1132	(ABC) transporter
FD724_RS02410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FD724_RS02415	COG0489	protein tyrosine kinase activity
FD724_RS02420	COG0438	transferase activity, transferring glycosyl groups
FD724_RS02425	COG0460	homoserine dehydrogenase
FD724_RS02445	COG1216	Glycosyl transferase, family 2
FD724_RS02455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FD724_RS02460	COG0579	oxidoreductase
FD724_RS02465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FD724_RS02480	COG4245	von Willebrand factor, type A
FD724_RS02485	COG0784	Response regulator, receiver
FD724_RS02490	COG0072	phenylalanine-tRNA ligase activity
FD724_RS02490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FD724_RS02600	COG2197	response regulator
FD724_RS02605	COG5002	protein histidine kinase activity
FD724_RS02645	COG1803	Methylglyoxal synthase
FD724_RS02650	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS02650	COG0515	serine threonine protein kinase
FD724_RS02675	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FD724_RS02730	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
FD724_RS02765	COG0222	ribosome binding
FD724_RS02780	COG0515	serine threonine protein kinase
FD724_RS02780	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS02790	COG5592	hemerythrin HHE cation binding domain
FD724_RS02795	COG1473	amidohydrolase
FD724_RS02805	COG0515	serine threonine protein kinase
FD724_RS02805	COG3266	domain, Protein
FD724_RS02810	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FD724_RS02815	COG0724	RNA recognition motif
FD724_RS02830	COG3237	CsbD-like
FD724_RS02880	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FD724_RS02890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FD724_RS02900	COG0829	nickel cation binding
FD724_RS02905	COG0831	urea catabolic process
FD724_RS02910	COG0832	Belongs to the urease beta subunit family
FD724_RS02920	COG0804	urea catabolic process
FD724_RS02940	COG0459	protein refolding
FD724_RS02945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FD724_RS02970	COG1012	belongs to the aldehyde dehydrogenase family
FD724_RS02975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FD724_RS02980	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FD724_RS03000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FD724_RS03005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FD724_RS03010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FD724_RS03015	COG0544	peptidyl-prolyl cis-trans isomerase activity
FD724_RS03020	COG0740	serine-type endopeptidase activity
FD724_RS03025	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FD724_RS03040	COG2188	Transcriptional regulator
FD724_RS03045	COG0412	Dienelactone hydrolase
FD724_RS03050	COG0539	negative regulation of cytoplasmic translation
FD724_RS03055	COG0515	serine threonine protein kinase
FD724_RS03100	COG1836	PFAM Integral membrane protein DUF92
FD724_RS03125	COG0017	Asparaginyl-tRNA synthetase
FD724_RS03145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FD724_RS03160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FD724_RS03165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FD724_RS03185	COG0601	transmembrane transport
FD724_RS03190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FD724_RS03215	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FD724_RS03220	COG1268	BioY protein
FD724_RS03230	COG0573	inorganic phosphate transmembrane transporter activity
FD724_RS03235	COG0581	inorganic phosphate transmembrane transporter activity
FD724_RS03240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FD724_RS03275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FD724_RS03285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FD724_RS03305	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FD724_RS03305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD724_RS03310	COG3437	response regulator, receiver
FD724_RS03315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FD724_RS03325	COG1446	asparaginase
FD724_RS03360	COG0167	dihydroorotate dehydrogenase activity
FD724_RS03385	COG2304	oxidoreductase activity
FD724_RS03405	COG2319	Wd-40 repeat
FD724_RS03405	COG3903	Transcriptional regulator
FD724_RS03410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FD724_RS03415	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS03415	COG0515	serine threonine protein kinase
FD724_RS03425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FD724_RS03445	COG3609	addiction module antidote protein, CC2985 family
FD724_RS03460	COG0514	ATP-dependent DNA helicase (RecQ)
FD724_RS03490	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FD724_RS03495	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FD724_RS03500	COG1234	tRNA 3'-trailer cleavage
FD724_RS03505	COG0196	riboflavin kinase activity
FD724_RS03510	COG0714	Associated with various cellular activities
FD724_RS03520	COG0653	protein targeting
FD724_RS03530	COG2226	methyltransferase
FD724_RS03545	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS03550	COG2197	response regulator
FD724_RS03585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FD724_RS03620	COG0824	Thioesterase
FD724_RS03630	COG4948	Mandelate Racemase Muconate Lactonizing
FD724_RS03635	COG1575	Belongs to the MenA family. Type 1 subfamily
FD724_RS03640	COG1169	isochorismate synthase
FD724_RS03650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FD724_RS03655	COG0784	Response regulator, receiver
FD724_RS03655	COG2205	protein histidine kinase activity
FD724_RS03665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FD724_RS03690	COG0667	Aldo Keto reductase
FD724_RS03695	COG1104	cysteine desulfurase activity
FD724_RS03705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FD724_RS03720	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FD724_RS03735	COG0640	Transcriptional regulator
FD724_RS03740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FD724_RS03745	COG0798	PFAM Bile acid sodium symporter
FD724_RS03750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FD724_RS03755	COG0431	NADPH-dependent FMN reductase
FD724_RS03765	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FD724_RS03775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FD724_RS03780	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FD724_RS03780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FD724_RS03785	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FD724_RS03790	COG2066	Belongs to the glutaminase family
FD724_RS03805	COG3852	Histidine kinase
FD724_RS03810	COG2267	carboxylic ester hydrolase activity
FD724_RS03820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FD724_RS03850	COG0564	pseudouridine synthase activity
FD724_RS03855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD724_RS03875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS03880	COG0778	Nitroreductase
FD724_RS03910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FD724_RS03915	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FD724_RS03940	COG1361	Conserved repeat domain
FD724_RS03975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FD724_RS03975	COG0426	domain, Protein
FD724_RS03985	COG0426	domain, Protein
FD724_RS03985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FD724_RS03990	COG0671	phosphoesterase, PA-phosphatase related
FD724_RS04015	COG2217	Heavy metal translocating P-type atpase
FD724_RS04030	COG1131	(ABC) transporter
FD724_RS04055	COG0788	formyltetrahydrofolate deformylase activity
FD724_RS04085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FD724_RS04110	COG0443	Heat shock 70 kDa protein
FD724_RS04125	COG0432	Pfam Uncharacterised protein family UPF0047
FD724_RS04145	COG2207	Transcriptional regulator
FD724_RS04165	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS04175	COG4221	oxidoreductase activity
FD724_RS04180	COG0667	Aldo Keto reductase
FD724_RS04185	COG1132	(ABC) transporter
FD724_RS04230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD724_RS04255	COG0793	Belongs to the peptidase S41A family
FD724_RS04265	COG4585	Histidine kinase
FD724_RS04270	COG2197	response regulator
FD724_RS04305	COG1741	Belongs to the pirin family
FD724_RS04320	COG0589	response to stress
FD724_RS04345	COG1049	propionate catabolic process, 2-methylcitrate cycle
FD724_RS04375	COG4242	Belongs to the peptidase S51 family
FD724_RS04380	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FD724_RS04395	COG1573	uracil-dna glycosylase
FD724_RS04410	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FD724_RS04420	COG2326	polyphosphate kinase activity
FD724_RS04425	COG2201	protein-glutamate methylesterase activity
FD724_RS04460	COG1040	competence protein
FD724_RS04470	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FD724_RS04480	COG0343	queuine tRNA-ribosyltransferase activity
FD724_RS04500	COG0589	response to stress
FD724_RS04505	COG3540	Alkaline phosphatase
FD724_RS04510	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FD724_RS04525	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FD724_RS04535	COG0617	tRNA 3'-terminal CCA addition
FD724_RS04535	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FD724_RS04535	COG0517	IMP dehydrogenase activity
FD724_RS04550	COG0488	(ABC) transporter
FD724_RS04555	COG3937	granule-associated protein
FD724_RS04560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FD724_RS04565	COG0631	protein serine/threonine phosphatase activity
FD724_RS04575	COG0515	serine threonine protein kinase
FD724_RS04580	COG1215	transferase activity, transferring glycosyl groups
FD724_RS04590	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FD724_RS04600	COG2211	Major facilitator Superfamily
FD724_RS04605	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FD724_RS04610	COG2205	protein histidine kinase activity
FD724_RS04620	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FD724_RS04625	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FD724_RS04635	COG2197	response regulator
FD724_RS04645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD724_RS04655	COG0793	Belongs to the peptidase S41A family
FD724_RS04660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FD724_RS04665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FD724_RS04680	COG0438	transferase activity, transferring glycosyl groups
FD724_RS04720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FD724_RS04735	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FD724_RS04740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FD724_RS04755	COG1940	carbohydrate kinase activity
FD724_RS04780	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
FD724_RS04815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FD724_RS04840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD724_RS04865	COG2319	Wd-40 repeat
FD724_RS04865	COG3903	Transcriptional regulator
FD724_RS04880	COG0375	protein maturation
FD724_RS04890	COG0409	Hydrogenase expression formation protein
FD724_RS04960	COG1278	Cold shock
FD724_RS05005	COG0633	Ferredoxin
FD724_RS05010	COG0316	Belongs to the HesB IscA family
FD724_RS05015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FD724_RS05025	COG5420	small protein containing a coiled-coil domain
FD724_RS05040	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS05045	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS05055	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS05060	COG0582	viral genome integration into host DNA
FD724_RS05085	COG0412	Dienelactone hydrolase
FD724_RS05125	COG3631	Ketosteroid isomerase-related protein
FD724_RS05200	COG0863	Belongs to the N(4) N(6)-methyltransferase family
FD724_RS05210	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS05225	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FD724_RS05225	COG2906	2 iron, 2 sulfur cluster binding
FD724_RS05225	COG0822	iron-sulfur transferase activity
FD724_RS05235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FD724_RS05270	COG1598	PFAM Uncharacterised protein family UPF0150
FD724_RS05295	COG1045	serine acetyltransferase
FD724_RS05310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FD724_RS05315	COG5554	nitrogen fixation
FD724_RS05365	COG0442	prolyl-tRNA aminoacylation
FD724_RS05375	COG0640	Transcriptional regulator
FD724_RS05380	COG0511	ligase activity, forming carbon-carbon bonds
FD724_RS05385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FD724_RS05390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FD724_RS05400	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FD724_RS05405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FD724_RS05410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FD724_RS05415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FD724_RS05420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FD724_RS05425	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FD724_RS05430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FD724_RS05435	COG0745	RESPONSE REGULATOR receiver
FD724_RS05440	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FD724_RS05455	COG2205	protein histidine kinase activity
FD724_RS05455	COG0784	Response regulator, receiver
FD724_RS05455	COG2198	Histidine kinase
FD724_RS05480	COG3206	protein involved in exopolysaccharide biosynthesis
FD724_RS05480	COG0489	protein tyrosine kinase activity
FD724_RS05505	COG4636	protein conserved in cyanobacteria
FD724_RS05520	COG1131	(ABC) transporter
FD724_RS05535	COG0556	nucleotide-excision repair
FD724_RS05545	COG3237	CsbD-like
FD724_RS05580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FD724_RS05585	COG2197	response regulator
FD724_RS05605	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FD724_RS05610	COG1982	Orn Lys Arg decarboxylase major
FD724_RS05630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FD724_RS05640	COG1492	cobalamin metabolic process
FD724_RS05665	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FD724_RS05680	COG0316	Belongs to the HesB IscA family
FD724_RS05695	COG1090	epimerase
FD724_RS05710	COG2217	Heavy metal translocating P-type atpase
FD724_RS05790	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS05855	COG2203	Gaf domain
FD724_RS05855	COG3706	GGDEF domain
FD724_RS05855	COG4251	negative regulation of phosphorylation
FD724_RS05855	COG5001	Diguanylate cyclase
FD724_RS05860	COG0745	RESPONSE REGULATOR receiver
FD724_RS05900	COG2205	protein histidine kinase activity
FD724_RS05915	COG0012	GTP binding
FD724_RS05925	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FD724_RS05930	COG0170	dolichyl monophosphate biosynthetic process
FD724_RS05940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FD724_RS05945	COG1372	Participates in initiation and elongation during chromosome replication
FD724_RS05945	COG0187	DNA topoisomerase II activity
FD724_RS05950	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD724_RS05955	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FD724_RS05960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FD724_RS05965	COG0784	Response regulator, receiver
FD724_RS05990	COG0577	efflux transmembrane transporter activity
FD724_RS05990	COG1136	(ABC) transporter
FD724_RS05995	COG1136	(ABC) transporter
FD724_RS06010	COG0475	glutathione-regulated potassium exporter activity
FD724_RS06045	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FD724_RS06065	COG0025	NhaP-type Na H and K H
FD724_RS06130	COG0484	heat shock protein binding
FD724_RS06135	COG0740	serine-type endopeptidase activity
FD724_RS06140	COG0740	serine-type endopeptidase activity
FD724_RS06145	COG2304	oxidoreductase activity
FD724_RS06150	COG2304	oxidoreductase activity
FD724_RS06175	COG3659	wide pore channel activity
FD724_RS06190	COG0346	lactoylglutathione lyase activity
FD724_RS06215	COG4956	integral membrane protein (PIN domain superfamily)
FD724_RS06220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FD724_RS06225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FD724_RS06230	COG0116	Belongs to the methyltransferase superfamily
FD724_RS06240	COG1902	pentaerythritol trinitrate reductase activity
FD724_RS06245	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FD724_RS06250	COG1619	proteins homologs of microcin C7 resistance protein MccF
FD724_RS06295	COG0667	Aldo Keto reductase
FD724_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS06315	COG0628	permease
FD724_RS06355	COG0667	Aldo Keto reductase
FD724_RS06360	COG0748	coenzyme F420 binding
FD724_RS06400	COG1254	Belongs to the acylphosphatase family
FD724_RS06415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FD724_RS06420	COG0582	viral genome integration into host DNA
FD724_RS07060	COG0582	viral genome integration into host DNA
FD724_RS07390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD724_RS07440	COG0776	regulation of translation
FD724_RS07650	COG1940	carbohydrate kinase activity
FD724_RS07660	COG0438	transferase activity, transferring glycosyl groups
FD724_RS07680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FD724_RS07690	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FD724_RS07700	COG2205	protein histidine kinase activity
FD724_RS07700	COG0784	Response regulator, receiver
FD724_RS07710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FD724_RS07715	COG0237	dephospho-CoA kinase activity
FD724_RS07735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FD724_RS07760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD724_RS07765	COG0154	amidase activity
FD724_RS07785	COG0367	asparagine synthase
FD724_RS07810	COG0019	diaminopimelate decarboxylase activity
FD724_RS07820	COG1285	pathogenesis
FD724_RS07830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FD724_RS07835	COG0860	N-Acetylmuramoyl-L-alanine amidase
FD724_RS07840	COG0860	N-Acetylmuramoyl-L-alanine amidase
FD724_RS07840	COG2247	cell wall binding repeat
FD724_RS07845	COG0475	glutathione-regulated potassium exporter activity
FD724_RS07860	COG0629	single-stranded DNA binding
FD724_RS07865	COG1077	Cell shape determining protein MreB Mrl
FD724_RS07885	COG0142	geranyltranstransferase activity
FD724_RS07905	COG1305	Transglutaminase-like
FD724_RS07925	COG0515	serine threonine protein kinase
FD724_RS07950	COG0038	chloride channel
FD724_RS07955	COG3206	protein involved in exopolysaccharide biosynthesis
FD724_RS07955	COG0489	protein tyrosine kinase activity
FD724_RS08040	COG2197	response regulator
FD724_RS08045	COG2197	response regulator
FD724_RS08065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FD724_RS08075	COG5398	heme oxygenase
FD724_RS08080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FD724_RS08105	COG0438	transferase activity, transferring glycosyl groups
FD724_RS08110	COG0438	transferase activity, transferring glycosyl groups
FD724_RS08125	COG0450	alkyl hydroperoxide reductase
FD724_RS08135	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FD724_RS08140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FD724_RS08200	COG0354	folic acid binding
FD724_RS08275	COG0315	cyclic pyranopterin monophosphate synthase activity
FD724_RS08285	COG2814	Major facilitator Superfamily
FD724_RS08290	COG0463	Glycosyl transferase, family 2
FD724_RS08325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FD724_RS08330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FD724_RS08335	COG1940	carbohydrate kinase activity
FD724_RS08345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FD724_RS08360	COG0492	ferredoxin-NADP+ reductase activity
FD724_RS08375	COG2226	methyltransferase
FD724_RS08380	COG4968	Prepilin-type N-terminal cleavage methylation domain
FD724_RS08420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FD724_RS08430	COG2089	acid synthase
FD724_RS08445	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FD724_RS08450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FD724_RS08455	COG1086	Polysaccharide biosynthesis protein
FD724_RS08470	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS08470	COG0515	serine threonine protein kinase
FD724_RS08480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FD724_RS08485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FD724_RS08490	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FD724_RS08495	COG0009	L-threonylcarbamoyladenylate synthase
FD724_RS08520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FD724_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS08540	COG1230	cation diffusion facilitator family transporter
FD724_RS08550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FD724_RS08555	COG0745	RESPONSE REGULATOR receiver
FD724_RS08560	COG0519	Catalyzes the synthesis of GMP from XMP
FD724_RS08560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FD724_RS08565	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FD724_RS08605	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FD724_RS08610	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FD724_RS08620	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FD724_RS08640	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FD724_RS08660	COG3659	wide pore channel activity
FD724_RS08665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FD724_RS08675	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FD724_RS08685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD724_RS08755	COG3659	wide pore channel activity
FD724_RS08770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FD724_RS08815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FD724_RS08820	COG1187	pseudouridine synthase activity
FD724_RS08825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD724_RS08830	COG0431	NADPH-dependent FMN reductase
FD724_RS08835	COG0277	FAD linked oxidase domain protein
FD724_RS08840	COG0247	lactate metabolic process
FD724_RS08855	COG2319	Wd-40 repeat
FD724_RS08855	COG4249	Peptidase C14 caspase catalytic subunit p20
FD724_RS08855	COG2319	Wd-40 repeat
FD724_RS08855	COG4249	Peptidase C14 caspase catalytic subunit p20
FD724_RS08860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FD724_RS08865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FD724_RS08895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FD724_RS08900	COG4636	protein conserved in cyanobacteria
FD724_RS08910	COG1017	nitric oxide dioxygenase activity
FD724_RS08910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FD724_RS08930	COG0848	biopolymer transport protein
FD724_RS08935	COG0811	peptide transport
FD724_RS08960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FD724_RS08965	COG0724	RNA recognition motif
FD724_RS08975	COG0667	Aldo Keto reductase
FD724_RS08980	COG1073	alpha beta
FD724_RS09010	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FD724_RS09025	COG0697	spore germination
FD724_RS09050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FD724_RS09065	COG0577	efflux transmembrane transporter activity
FD724_RS09065	COG1136	(ABC) transporter
FD724_RS09070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD724_RS09080	COG0445	tRNA wobble uridine modification
FD724_RS09135	COG2873	o-acetylhomoserine
FD724_RS09140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FD724_RS09145	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FD724_RS09160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FD724_RS09165	COG2226	methyltransferase
FD724_RS09170	COG1690	Belongs to the RtcB family
FD724_RS09170	COG1690	Belongs to the RtcB family
FD724_RS09185	COG0508	dehydrogenase complex catalyzes the overall conversion of
FD724_RS09200	COG1022	Amp-dependent synthetase and ligase
FD724_RS09225	COG0535	radical SAM domain protein
FD724_RS09230	COG2814	Major facilitator Superfamily
FD724_RS09240	COG0514	ATP-dependent DNA helicase (RecQ)
FD724_RS09255	COG1672	PFAM Archaeal ATPase
FD724_RS09255	COG2319	Wd-40 repeat
FD724_RS09275	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FD724_RS09285	COG0572	uridine kinase
FD724_RS09295	COG2003	Belongs to the UPF0758 family
FD724_RS09350	COG0464	growth
FD724_RS09405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FD724_RS09410	COG3659	wide pore channel activity
FD724_RS09420	COG3118	belongs to the thioredoxin family
FD724_RS09425	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS09440	COG5002	protein histidine kinase activity
FD724_RS09445	COG0745	RESPONSE REGULATOR receiver
FD724_RS09460	COG1116	anion transmembrane transporter activity
FD724_RS09470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS09470	COG1116	anion transmembrane transporter activity
FD724_RS09475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FD724_RS09480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS09495	COG0745	RESPONSE REGULATOR receiver
FD724_RS09500	COG2226	methyltransferase
FD724_RS09520	COG0604	alcohol dehydrogenase
FD724_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS09520	COG3321	synthase
FD724_RS09530	COG3012	SEC-C Motif Domain Protein
FD724_RS09540	COG4974	Belongs to the 'phage' integrase family
FD724_RS09555	COG1162	GTPase activity
FD724_RS09570	COG0440	acetolactate synthase activity
FD724_RS09590	COG2010	Cytochrome c
FD724_RS09605	COG2203	Gaf domain
FD724_RS09605	COG0840	transmembrane signaling receptor activity
FD724_RS09640	COG0300	oxidoreductase activity
FD724_RS09660	COG3852	Histidine kinase
FD724_RS09680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FD724_RS09685	COG2205	protein histidine kinase activity
FD724_RS09685	COG2202	Pas domain
FD724_RS09715	COG2329	Antibiotic biosynthesis monooxygenase
FD724_RS09720	COG0534	Mate efflux family protein
FD724_RS09740	COG2205	protein histidine kinase activity
FD724_RS09740	COG2202	Pas domain
FD724_RS09755	COG0735	belongs to the Fur family
FD724_RS09760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD724_RS09765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FD724_RS09770	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FD724_RS09875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FD724_RS09880	COG1266	CAAX protease self-immunity
FD724_RS09900	COG0515	serine threonine protein kinase
FD724_RS09900	COG3266	domain, Protein
FD724_RS09940	COG4178	(ABC) transporter
FD724_RS09945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FD724_RS09960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FD724_RS09985	COG2226	methyltransferase
FD724_RS10020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FD724_RS10025	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FD724_RS10055	COG3706	GGDEF domain
FD724_RS10055	COG2203	Gaf domain
FD724_RS10055	COG5001	Diguanylate cyclase
FD724_RS10055	COG4251	negative regulation of phosphorylation
FD724_RS10075	COG2815	serine threonine protein kinase
FD724_RS10075	COG0515	serine threonine protein kinase
FD724_RS10090	COG0205	6-phosphofructokinase activity
FD724_RS10095	COG0745	RESPONSE REGULATOR receiver
FD724_RS10100	COG5002	protein histidine kinase activity
FD724_RS10105	COG0574	Belongs to the PEP-utilizing enzyme family
FD724_RS10105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FD724_RS10130	COG0167	dihydroorotate dehydrogenase activity
FD724_RS10135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FD724_RS10135	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FD724_RS10135	COG1013	pyruvate-flavodoxin oxidoreductase activity
FD724_RS10135	COG0674	pyruvate-flavodoxin oxidoreductase activity
FD724_RS10160	COG0300	oxidoreductase activity
FD724_RS10160	COG0318	PFAM AMP-dependent synthetase and ligase
FD724_RS10160	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS10160	COG3321	synthase
FD724_RS10160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FD724_RS10180	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS10200	COG0747	negative chemotaxis
FD724_RS10225	COG1696	Membrane protein involved in D-alanine export
FD724_RS10240	COG4178	(ABC) transporter
FD724_RS10265	COG3259	Nickel-dependent hydrogenase
FD724_RS10275	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS10305	COG0842	Transport permease protein
FD724_RS10310	COG1129	ABC transporter
FD724_RS10310	COG0842	Transport permease protein
FD724_RS10315	COG1131	(ABC) transporter
FD724_RS10330	COG0071	Belongs to the small heat shock protein (HSP20) family
FD724_RS10360	COG0784	Response regulator, receiver
FD724_RS10365	COG4251	negative regulation of phosphorylation
FD724_RS10370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FD724_RS10375	COG0745	RESPONSE REGULATOR receiver
FD724_RS10380	COG0095	Lipoate-protein ligase
FD724_RS10390	COG0714	Associated with various cellular activities
FD724_RS10400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FD724_RS10435	COG0784	Response regulator, receiver
FD724_RS10435	COG2205	protein histidine kinase activity
FD724_RS10445	COG0515	serine threonine protein kinase
FD724_RS10445	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS10450	COG0784	Response regulator, receiver
FD724_RS10450	COG2198	Histidine kinase
FD724_RS10450	COG5002	protein histidine kinase activity
FD724_RS10460	COG0515	serine threonine protein kinase
FD724_RS10460	COG3266	domain, Protein
FD724_RS10465	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FD724_RS10500	COG0666	response to abiotic stimulus
FD724_RS10530	COG1126	abc transporter atp-binding protein
FD724_RS10535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FD724_RS10540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FD724_RS10545	COG0483	inositol monophosphate 1-phosphatase activity
FD724_RS10590	COG0371	Dehydrogenase
FD724_RS10595	COG0436	Aminotransferase
FD724_RS10610	COG2205	protein histidine kinase activity
FD724_RS10610	COG0784	Response regulator, receiver
FD724_RS10700	COG0837	glucose binding
FD724_RS10710	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FD724_RS10730	COG1136	(ABC) transporter
FD724_RS10730	COG0577	efflux transmembrane transporter activity
FD724_RS10735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD724_RS10740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FD724_RS10755	COG0180	Tryptophanyl-tRNA synthetase
FD724_RS10795	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FD724_RS10840	COG0793	Belongs to the peptidase S41A family
FD724_RS10845	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FD724_RS10880	COG2274	protein secretion by the type I secretion system
FD724_RS10885	COG2274	protein secretion by the type I secretion system
FD724_RS10925	COG0745	RESPONSE REGULATOR receiver
FD724_RS10930	COG5002	protein histidine kinase activity
FD724_RS10965	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FD724_RS10980	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FD724_RS10985	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FD724_RS10990	COG2080	2 iron, 2 sulfur cluster binding
FD724_RS11000	COG4942	peptidase
FD724_RS11000	COG1388	LysM domain
FD724_RS11005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD724_RS11020	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FD724_RS11025	COG0859	PFAM glycosyl transferase family 9
FD724_RS11045	COG2197	response regulator
FD724_RS11050	COG0170	dolichyl monophosphate biosynthetic process
FD724_RS11065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FD724_RS11070	COG0776	regulation of translation
FD724_RS11100	COG0285	dihydrofolate synthase activity
FD724_RS11125	COG0612	Peptidase, M16
FD724_RS11135	COG0024	Methionine aminopeptidase
FD724_RS11150	COG0154	amidase activity
FD724_RS11160	COG2010	Cytochrome c
FD724_RS11170	COG0742	ribosomal rna small subunit methyltransferase
FD724_RS11175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FD724_RS11190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FD724_RS11210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FD724_RS11215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FD724_RS11220	COG0085	RNA polymerase activity
FD724_RS11225	COG0084	hydrolase, TatD family'
FD724_RS11230	COG0268	Binds directly to 16S ribosomal RNA
FD724_RS11235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FD724_RS11240	COG0589	response to stress
FD724_RS11250	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FD724_RS11260	COG2084	Dehydrogenase
FD724_RS11310	COG0649	NAD binding
FD724_RS11320	COG2264	protein methyltransferase activity
FD724_RS11325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FD724_RS11390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FD724_RS11410	COG1361	Conserved repeat domain
FD724_RS11425	COG0668	transmembrane transport
FD724_RS11430	COG0123	including yeast histone deacetylase and acetoin utilization protein
FD724_RS11440	COG3266	domain, Protein
FD724_RS11440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FD724_RS11445	COG0385	Bile acid
FD724_RS11465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FD724_RS11475	COG0484	heat shock protein binding
FD724_RS11490	COG0450	alkyl hydroperoxide reductase
FD724_RS11505	COG0739	heme binding
FD724_RS11510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FD724_RS11515	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FD724_RS11525	COG1404	Belongs to the peptidase S8 family
FD724_RS11535	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FD724_RS11575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FD724_RS11580	COG3536	Protein conserved in bacteria
FD724_RS11595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD724_RS11620	COG1063	alcohol dehydrogenase
FD724_RS11625	COG3527	Alpha-acetolactate decarboxylase
FD724_RS11645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FD724_RS11650	COG0406	alpha-ribazole phosphatase activity
FD724_RS11695	COG5001	Diguanylate cyclase
FD724_RS11695	COG4251	negative regulation of phosphorylation
FD724_RS11695	COG3706	GGDEF domain
FD724_RS11695	COG2203	Gaf domain
FD724_RS11700	COG5002	protein histidine kinase activity
FD724_RS11705	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FD724_RS11710	COG0830	nickel cation binding
FD724_RS11715	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FD724_RS11720	COG4172	Belongs to the ABC transporter superfamily
FD724_RS11740	COG0629	single-stranded DNA binding
FD724_RS11750	COG3842	ATPase activity
FD724_RS11755	COG1051	belongs to the nudix hydrolase family
FD724_RS11760	COG0126	phosphoglycerate kinase activity
FD724_RS11765	COG0589	response to stress
FD724_RS11780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FD724_RS11780	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FD724_RS11825	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FD724_RS11830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FD724_RS11835	COG1333	cytochrome c biogenesis protein
FD724_RS11840	COG4232	protein-disulfide reductase activity
FD724_RS11845	COG2205	protein histidine kinase activity
FD724_RS11860	COG0784	Response regulator, receiver
FD724_RS11870	COG0587	DNA-directed DNA polymerase activity
FD724_RS11900	COG0583	DNA-binding transcription factor activity
FD724_RS11920	COG2226	methyltransferase
FD724_RS11930	COG1741	Belongs to the pirin family
FD724_RS11935	COG0783	Belongs to the Dps family
FD724_RS11940	COG0667	Aldo Keto reductase
FD724_RS11980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FD724_RS11990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FD724_RS11990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FD724_RS12025	COG2022	thiamine diphosphate biosynthetic process
FD724_RS12025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD724_RS12065	COG5433	transposase activity
FD724_RS12100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FD724_RS12110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FD724_RS12140	COG0596	Alpha beta hydrolase
FD724_RS12150	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FD724_RS12175	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FD724_RS12180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FD724_RS12200	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
FD724_RS12210	COG0270	DNA (cytosine-5-)-methyltransferase activity
FD724_RS12250	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FD724_RS12255	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS12255	COG0515	serine threonine protein kinase
FD724_RS12275	COG0673	inositol 2-dehydrogenase activity
FD724_RS12295	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FD724_RS12315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FD724_RS12335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FD724_RS12340	COG0259	pyridoxamine-phosphate oxidase activity
FD724_RS12345	COG0628	permease
FD724_RS12355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FD724_RS12360	COG1166	arginine decarboxylase activity
FD724_RS12365	COG0105	UTP biosynthetic process
FD724_RS12370	COG0861	Integral membrane protein TerC family
FD724_RS12395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FD724_RS12420	COG0625	glutathione transferase activity
FD724_RS12435	COG2226	methyltransferase
FD724_RS12455	COG1902	pentaerythritol trinitrate reductase activity
FD724_RS12460	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS12465	COG3118	belongs to the thioredoxin family
FD724_RS12470	COG0640	Transcriptional regulator
FD724_RS12485	COG1215	transferase activity, transferring glycosyl groups
FD724_RS12490	COG1657	PFAM Prenyltransferase squalene oxidase
FD724_RS12510	COG3631	Ketosteroid isomerase-related protein
FD724_RS12525	COG0693	protein deglycase activity
FD724_RS12550	COG0649	NAD binding
FD724_RS12555	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FD724_RS12565	COG3239	Fatty acid desaturase
FD724_RS12570	COG3239	Fatty acid desaturase
FD724_RS12580	COG0745	RESPONSE REGULATOR receiver
FD724_RS12585	COG5000	phosphorelay sensor kinase activity
FD724_RS12585	COG5002	protein histidine kinase activity
FD724_RS12590	COG4122	O-methyltransferase activity
FD724_RS12605	COG0163	prenyltransferase activity
FD724_RS12610	COG0557	exoribonuclease II activity
FD724_RS12620	COG0740	serine-type endopeptidase activity
FD724_RS12630	COG1331	Highly conserved protein containing a thioredoxin domain
FD724_RS12635	COG0746	molybdenum cofactor guanylyltransferase activity
FD724_RS12645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FD724_RS12650	COG0672	)-iron permease
FD724_RS12665	COG2132	Multicopper oxidase
FD724_RS12685	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FD724_RS12715	COG0671	phosphoesterase, PA-phosphatase related
FD724_RS12725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD724_RS12725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD724_RS12735	COG0561	phosphatase activity
FD724_RS12745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD724_RS12760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FD724_RS12765	COG0515	serine threonine protein kinase
FD724_RS12770	COG0583	DNA-binding transcription factor activity
FD724_RS12780	COG3118	belongs to the thioredoxin family
FD724_RS12785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FD724_RS12815	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS12885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FD724_RS12905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FD724_RS12910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FD724_RS12915	COG1285	pathogenesis
FD724_RS12920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FD724_RS12920	COG0574	Belongs to the PEP-utilizing enzyme family
FD724_RS12945	COG3659	wide pore channel activity
FD724_RS12955	COG1122	ATPase activity
FD724_RS12965	COG0310	cobalt ion transport
FD724_RS12980	COG5002	protein histidine kinase activity
FD724_RS12995	COG3659	wide pore channel activity
FD724_RS13000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FD724_RS13005	COG0716	FMN binding
FD724_RS13010	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FD724_RS13025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FD724_RS13045	COG2205	protein histidine kinase activity
FD724_RS13050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FD724_RS13060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD724_RS13065	COG0010	Belongs to the arginase family
FD724_RS13075	COG0504	CTP synthase activity
FD724_RS13080	COG0860	N-Acetylmuramoyl-L-alanine amidase
FD724_RS13095	COG0792	nuclease activity
FD724_RS13105	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FD724_RS13110	COG1045	serine acetyltransferase
FD724_RS13120	COG0569	domain protein
FD724_RS13125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FD724_RS13130	COG2226	methyltransferase
FD724_RS13135	COG1120	ATPase activity
FD724_RS13150	COG1175	transmembrane transport
FD724_RS13160	COG2205	protein histidine kinase activity
FD724_RS13160	COG5002	protein histidine kinase activity
FD724_RS13160	COG0784	Response regulator, receiver
FD724_RS13175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FD724_RS13180	COG2201	protein-glutamate methylesterase activity
FD724_RS13195	COG0840	transmembrane signaling receptor activity
FD724_RS13195	COG2203	Gaf domain
FD724_RS13205	COG2198	Histidine kinase
FD724_RS13205	COG0784	Response regulator, receiver
FD724_RS13205	COG0643	Histidine kinase
FD724_RS13215	COG1176	ABC-type spermidine putrescine transport system, permease component I
FD724_RS13220	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FD724_RS13235	COG0328	RNA-DNA hybrid ribonuclease activity
FD724_RS13240	COG0814	amino acid
FD724_RS13245	COG5002	protein histidine kinase activity
FD724_RS13250	COG0840	transmembrane signaling receptor activity
FD724_RS13250	COG2203	Gaf domain
FD724_RS13260	COG2234	aminopeptidase activity
FD724_RS13265	COG0443	Heat shock 70 kDa protein
FD724_RS13270	COG0484	heat shock protein binding
FD724_RS13275	COG0484	heat shock protein binding
FD724_RS13295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FD724_RS13300	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FD724_RS13305	COG0019	diaminopimelate decarboxylase activity
FD724_RS13310	COG0456	acetyltransferase
FD724_RS13315	COG0542	response to heat
FD724_RS13335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FD724_RS13365	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FD724_RS13385	COG0824	Thioesterase
FD724_RS13400	COG2198	Histidine kinase
FD724_RS13400	COG0784	Response regulator, receiver
FD724_RS13400	COG0643	Histidine kinase
FD724_RS13405	COG0840	transmembrane signaling receptor activity
FD724_RS13420	COG0784	Response regulator, receiver
FD724_RS13430	COG0037	tRNA processing
FD724_RS13445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FD724_RS13475	COG0439	Biotin carboxylase
FD724_RS13490	COG0515	serine threonine protein kinase
FD724_RS13525	COG0492	ferredoxin-NADP+ reductase activity
FD724_RS13530	COG0233	cytoplasmic translational termination
FD724_RS13535	COG0528	UMP kinase activity
FD724_RS13540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FD724_RS13595	COG0277	FAD linked oxidase domain protein
FD724_RS13610	COG4251	negative regulation of phosphorylation
FD724_RS13610	COG5001	Diguanylate cyclase
FD724_RS13610	COG2203	Gaf domain
FD724_RS13610	COG3706	GGDEF domain
FD724_RS13650	COG1216	Glycosyl transferase, family 2
FD724_RS13655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD724_RS13670	COG5433	transposase activity
FD724_RS13685	COG5001	Diguanylate cyclase
FD724_RS13685	COG4251	negative regulation of phosphorylation
FD724_RS13685	COG3706	GGDEF domain
FD724_RS13685	COG2203	Gaf domain
FD724_RS13700	COG0643	Histidine kinase
FD724_RS13700	COG2198	Histidine kinase
FD724_RS13700	COG0784	Response regulator, receiver
FD724_RS13705	COG2203	Gaf domain
FD724_RS13705	COG0840	transmembrane signaling receptor activity
FD724_RS13720	COG0784	Response regulator, receiver
FD724_RS13740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD724_RS13795	COG2319	Wd-40 repeat
FD724_RS13795	COG4249	Peptidase C14 caspase catalytic subunit p20
FD724_RS13855	COG5002	protein histidine kinase activity
FD724_RS13860	COG0745	RESPONSE REGULATOR receiver
FD724_RS13875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FD724_RS13885	COG0438	transferase activity, transferring glycosyl groups
FD724_RS13900	COG0561	phosphatase activity
FD724_RS13905	COG1480	7TM receptor with intracellular HD hydrolase
FD724_RS13955	COG0701	Predicted permease
FD724_RS13960	COG3408	Glycogen debranching enzyme
FD724_RS13960	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FD724_RS13965	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS13985	COG3386	PFAM SMP-30 Gluconolaconase
FD724_RS13990	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FD724_RS14000	COG0745	RESPONSE REGULATOR receiver
FD724_RS14005	COG5002	protein histidine kinase activity
FD724_RS14015	COG0668	transmembrane transport
FD724_RS14110	COG2319	Wd-40 repeat
FD724_RS14145	COG0138	bifunctional purine biosynthesis protein purh
FD724_RS14155	COG0745	RESPONSE REGULATOR receiver
FD724_RS14165	COG3781	membrane
FD724_RS14175	COG3266	domain, Protein
FD724_RS14175	COG0515	serine threonine protein kinase
FD724_RS14185	COG1129	ABC transporter
FD724_RS14185	COG0842	Transport permease protein
FD724_RS14190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FD724_RS14205	COG1316	TRANSCRIPTIONal
FD724_RS14210	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS14215	COG2203	Gaf domain
FD724_RS14215	COG5001	Diguanylate cyclase
FD724_RS14215	COG3706	GGDEF domain
FD724_RS14215	COG4251	negative regulation of phosphorylation
FD724_RS14220	COG0728	peptidoglycan biosynthetic process
FD724_RS14245	COG0110	maltose O-acetyltransferase activity
FD724_RS14290	COG1136	(ABC) transporter
FD724_RS14295	COG3631	Ketosteroid isomerase-related protein
FD724_RS14305	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FD724_RS14320	COG2204	response regulator
FD724_RS14325	COG2197	response regulator
FD724_RS14330	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FD724_RS14335	COG2884	Cell division ATP-binding protein ftsE
FD724_RS14385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FD724_RS14400	COG5002	protein histidine kinase activity
FD724_RS14415	COG0789	Transcriptional regulator
FD724_RS14475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FD724_RS14495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FD724_RS14505	COG0739	heme binding
FD724_RS14505	COG1196	nuclear chromosome segregation
FD724_RS14505	COG0741	lytic transglycosylase activity
FD724_RS14515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FD724_RS14515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FD724_RS14545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD724_RS14560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD724_RS14565	COG2197	response regulator
FD724_RS14570	COG0033	Phosphoglucomutase
FD724_RS14620	COG0129	dihydroxy-acid dehydratase activity
FD724_RS14625	COG0583	DNA-binding transcription factor activity
FD724_RS14635	COG1910	domain protein
FD724_RS14645	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS14650	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS14665	COG0443	Heat shock 70 kDa protein
FD724_RS14670	COG0484	heat shock protein binding
FD724_RS14675	COG0789	Transcriptional regulator
FD724_RS14695	COG1960	acyl-CoA dehydrogenase activity
FD724_RS14775	COG1024	Enoyl-CoA hydratase
FD724_RS14780	COG1024	Enoyl-CoA hydratase
FD724_RS14785	COG3425	synthase
FD724_RS14800	COG0508	dehydrogenase complex catalyzes the overall conversion of
FD724_RS14805	COG3958	Transketolase
FD724_RS14810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FD724_RS14860	COG0217	transcriptional regulatory protein
FD724_RS14870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD724_RS14940	COG2198	Histidine kinase
FD724_RS14940	COG0784	Response regulator, receiver
FD724_RS14940	COG0643	Histidine kinase
FD724_RS14945	COG2203	Gaf domain
FD724_RS14945	COG0840	transmembrane signaling receptor activity
FD724_RS14955	COG0745	RESPONSE REGULATOR receiver
FD724_RS14955	COG3292	Two component regulator propeller
FD724_RS14955	COG2205	protein histidine kinase activity
FD724_RS14965	COG0784	Response regulator, receiver
FD724_RS14970	COG0561	phosphatase activity
FD724_RS14985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FD724_RS15015	COG2062	phosphohistidine phosphatase, SixA
FD724_RS15020	COG0372	Belongs to the citrate synthase family
FD724_RS15030	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FD724_RS15035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS15040	COG0839	Belongs to the complex I subunit 6 family
FD724_RS15045	COG0713	ATP synthesis coupled electron transport
FD724_RS15050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FD724_RS15085	COG1215	transferase activity, transferring glycosyl groups
FD724_RS15095	COG0110	maltose O-acetyltransferase activity
FD724_RS15115	COG1063	alcohol dehydrogenase
FD724_RS15125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FD724_RS15150	COG4106	trans-aconitate 2-methyltransferase activity
FD724_RS15155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FD724_RS15170	COG1181	Belongs to the D-alanine--D-alanine ligase family
FD724_RS15175	COG1253	flavin adenine dinucleotide binding
FD724_RS15180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FD724_RS15195	COG2814	Major facilitator Superfamily
FD724_RS15200	COG0175	sulfate reduction
FD724_RS15215	COG0516	GMP reductase activity
FD724_RS15220	COG3118	belongs to the thioredoxin family
FD724_RS15225	COG2095	MarC family integral membrane protein
FD724_RS15250	COG1309	transcriptional regulator
FD724_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS15270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FD724_RS15300	COG1136	(ABC) transporter
FD724_RS15300	COG0577	efflux transmembrane transporter activity
FD724_RS15325	COG0052	Belongs to the universal ribosomal protein uS2 family
FD724_RS15330	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FD724_RS15340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FD724_RS15360	COG0137	argininosuccinate synthase activity
FD724_RS15365	COG0586	Pfam SNARE associated Golgi protein
FD724_RS15380	COG0360	Binds together with S18 to 16S ribosomal RNA
FD724_RS15435	COG4447	cellulose binding
FD724_RS15440	COG1773	rubredoxin
FD724_RS15445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS15450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS15455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS15515	COG0515	serine threonine protein kinase
FD724_RS15520	COG1845	cytochrome c oxidase, subunit III
FD724_RS15525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FD724_RS15530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FD724_RS15540	COG0109	protoheme IX farnesyltransferase activity
FD724_RS15560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD724_RS15585	COG2376	Dihydroxyacetone kinase
FD724_RS15590	COG1461	Dihydroxyacetone kinase
FD724_RS15595	COG0424	maF-like protein
FD724_RS15610	COG0667	Aldo Keto reductase
FD724_RS15630	COG4372	Transposase
FD724_RS15635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD724_RS15640	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FD724_RS15645	COG0131	Imidazoleglycerol-phosphate dehydratase
FD724_RS15650	COG1131	(ABC) transporter
FD724_RS15655	COG1596	polysaccharide export
FD724_RS15675	COG0438	transferase activity, transferring glycosyl groups
FD724_RS15685	COG0463	Glycosyl transferase, family 2
FD724_RS15685	COG1216	Glycosyl transferase, family 2
FD724_RS15695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FD724_RS15700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FD724_RS15710	COG1253	flavin adenine dinucleotide binding
FD724_RS15715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FD724_RS15730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FD724_RS15765	COG1122	ATPase activity
FD724_RS15770	COG0357	Ribosomal RNA small subunit methyltransferase G
FD724_RS15780	COG3842	ATPase activity
FD724_RS15785	COG1598	PFAM Uncharacterised protein family UPF0150
FD724_RS15790	COG0515	serine threonine protein kinase
FD724_RS15795	COG0538	isocitrate dehydrogenase activity
FD724_RS15800	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FD724_RS15820	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FD724_RS15830	COG0667	Aldo Keto reductase
FD724_RS15850	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FD724_RS15865	COG1696	Membrane protein involved in D-alanine export
FD724_RS15890	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FD724_RS15900	COG2046	Belongs to the sulfate adenylyltransferase family
FD724_RS15925	COG0482	sulfurtransferase activity
FD724_RS15975	COG0390	transport system, permease component
FD724_RS15985	COG0312	modulator of DNA gyrase
FD724_RS15990	COG0312	modulator of DNA gyrase
FD724_RS15995	COG0463	Glycosyl transferase, family 2
FD724_RS16005	COG2076	Multidrug Resistance protein
FD724_RS16010	COG2076	Multidrug Resistance protein
FD724_RS16025	COG2183	response to ionizing radiation
FD724_RS16050	COG0124	histidyl-tRNA synthetase
FD724_RS16055	COG0157	Belongs to the NadC ModD family
FD724_RS16085	COG1234	tRNA 3'-trailer cleavage
FD724_RS16090	COG0489	protein tyrosine kinase activity
FD724_RS16095	COG2385	sporulation resulting in formation of a cellular spore
FD724_RS16115	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FD724_RS16140	COG0501	Belongs to the peptidase M48B family
FD724_RS16145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FD724_RS16155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FD724_RS16175	COG3033	Beta-eliminating lyase
FD724_RS16200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FD724_RS16210	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FD724_RS16215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FD724_RS16230	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FD724_RS16240	COG0406	alpha-ribazole phosphatase activity
FD724_RS16245	COG1132	(ABC) transporter
FD724_RS16270	COG1196	nuclear chromosome segregation
FD724_RS16280	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FD724_RS16290	COG2852	Protein conserved in bacteria
FD724_RS16315	COG1045	serine acetyltransferase
FD724_RS16335	COG1420	regulation of RNA biosynthetic process
FD724_RS16375	COG1819	glycosyl
FD724_RS16385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FD724_RS16440	COG2226	methyltransferase
FD724_RS16455	COG3510	cephalosporin hydroxylase
FD724_RS16485	COG2203	Gaf domain
FD724_RS16485	COG3706	GGDEF domain
FD724_RS16485	COG5001	Diguanylate cyclase
FD724_RS16485	COG4251	negative regulation of phosphorylation
FD724_RS16520	COG0300	oxidoreductase activity
FD724_RS16560	COG1252	NADH dehydrogenase
FD724_RS16565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FD724_RS16570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FD724_RS16575	COG1116	anion transmembrane transporter activity
FD724_RS16580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FD724_RS16585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD724_RS16590	COG3659	wide pore channel activity
FD724_RS16595	COG0398	Pfam SNARE associated Golgi protein
FD724_RS16600	COG0463	Glycosyl transferase, family 2
FD724_RS16630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS16645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FD724_RS16660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS16665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS16680	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS16680	COG0515	serine threonine protein kinase
FD724_RS16725	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FD724_RS16740	COG0222	ribosome binding
FD724_RS16745	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FD724_RS16750	COG0081	regulation of translation
FD724_RS16755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FD724_RS16760	COG0250	Participates in transcription elongation, termination and antitermination
FD724_RS16765	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FD724_RS16775	COG0335	large ribosomal subunit rRNA binding
FD724_RS16780	COG1215	transferase activity, transferring glycosyl groups
FD724_RS16785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FD724_RS16805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FD724_RS16810	COG0583	DNA-binding transcription factor activity
FD724_RS16825	COG0811	peptide transport
FD724_RS16835	COG0275	rRNA processing
FD724_RS16860	COG0745	RESPONSE REGULATOR receiver
FD724_RS16885	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS16900	COG0572	uridine kinase
FD724_RS16915	COG0501	Belongs to the peptidase M48B family
FD724_RS16930	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FD724_RS16975	COG5002	protein histidine kinase activity
FD724_RS17005	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FD724_RS17010	COG2201	protein-glutamate methylesterase activity
FD724_RS17035	COG2203	Gaf domain
FD724_RS17035	COG3706	GGDEF domain
FD724_RS17035	COG5001	Diguanylate cyclase
FD724_RS17035	COG4251	negative regulation of phosphorylation
FD724_RS17040	COG2205	protein histidine kinase activity
FD724_RS17050	COG3240	lipase activity
FD724_RS17070	COG1361	Conserved repeat domain
FD724_RS17090	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FD724_RS17090	COG3266	domain, Protein
FD724_RS17100	COG0195	Participates in both transcription termination and antitermination
FD724_RS17105	COG0779	Required for maturation of 30S ribosomal subunits
FD724_RS17125	COG0515	serine threonine protein kinase
FD724_RS17135	COG0515	serine threonine protein kinase
FD724_RS17145	COG0515	serine threonine protein kinase
FD724_RS17155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FD724_RS17190	COG0517	IMP dehydrogenase activity
FD724_RS17190	COG0516	GMP reductase activity
FD724_RS17195	COG0494	nUDIX hydrolase
FD724_RS17205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD724_RS17210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FD724_RS17215	COG0783	Belongs to the Dps family
FD724_RS17250	COG3639	organic phosphonate transmembrane transporter activity
FD724_RS17255	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FD724_RS17265	COG0251	oxidation-reduction process
FD724_RS17275	COG1640	4-alpha-glucanotransferase
FD724_RS17285	COG1187	pseudouridine synthase activity
FD724_RS17295	COG0575	Belongs to the CDS family
FD724_RS17305	COG0515	serine threonine protein kinase
FD724_RS17310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FD724_RS17315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FD724_RS17315	COG0189	ligase activity
FD724_RS17320	COG4242	Belongs to the peptidase S51 family
FD724_RS17325	COG0336	Belongs to the RNA methyltransferase TrmD family
FD724_RS17330	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FD724_RS17340	COG0747	negative chemotaxis
FD724_RS17345	COG1691	(AIR) carboxylase
FD724_RS17355	COG0165	Argininosuccinate lyase
FD724_RS17380	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FD724_RS17385	COG0426	domain, Protein
FD724_RS17385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FD724_RS17390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FD724_RS17390	COG0426	domain, Protein
FD724_RS17400	COG0724	RNA recognition motif
FD724_RS17410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD724_RS17415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD724_RS17425	COG0297	glycogen (starch) synthase activity
FD724_RS17435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FD724_RS17455	COG1959	2 iron, 2 sulfur cluster binding
FD724_RS17460	COG2205	protein histidine kinase activity
FD724_RS17465	COG1554	hydrolase, family 65, central catalytic
FD724_RS17470	COG0438	transferase activity, transferring glycosyl groups
FD724_RS17495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FD724_RS17500	COG0303	'Molybdopterin
FD724_RS17515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FD724_RS17520	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FD724_RS17525	COG0557	exoribonuclease II activity
FD724_RS17530	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FD724_RS17535	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FD724_RS17560	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS17570	COG2161	toxin-antitoxin pair type II binding
FD724_RS17590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FD724_RS17595	COG4783	chaperone-mediated protein folding
FD724_RS17630	COG2082	Precorrin-8x methylmutase
FD724_RS17640	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FD724_RS17690	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FD724_RS17695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FD724_RS17705	COG0745	RESPONSE REGULATOR receiver
FD724_RS17715	COG0134	indole-3-glycerol-phosphate synthase activity
FD724_RS17740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD724_RS17770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FD724_RS17785	COG0587	DNA-directed DNA polymerase activity
FD724_RS17790	COG1301	dicarboxylic acid transport
FD724_RS17805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FD724_RS17805	COG0426	domain, Protein
FD724_RS17810	COG0426	domain, Protein
FD724_RS17810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FD724_RS17825	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FD724_RS17830	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FD724_RS17835	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FD724_RS17840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FD724_RS17850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FD724_RS17855	COG0356	it plays a direct role in the translocation of protons across the membrane
FD724_RS17865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FD724_RS17885	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FD724_RS17885	COG0237	dephospho-CoA kinase activity
FD724_RS17925	COG3852	Histidine kinase
FD724_RS17930	COG0772	Belongs to the SEDS family
FD724_RS17950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FD724_RS17955	COG0719	Fe-S assembly protein
FD724_RS17960	COG0396	ATPase activity
FD724_RS17965	COG0719	Fe-S assembly protein
FD724_RS17990	COG0393	Putative heavy-metal-binding
FD724_RS18030	COG2319	Wd-40 repeat
FD724_RS18030	COG4249	Peptidase C14 caspase catalytic subunit p20
FD724_RS18050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FD724_RS18055	COG0189	ligase activity
FD724_RS18060	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FD724_RS18080	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FD724_RS18090	COG4221	oxidoreductase activity
FD724_RS18105	COG1032	radical SAM domain protein
FD724_RS18125	COG2319	Wd-40 repeat
FD724_RS18125	COG1672	PFAM Archaeal ATPase
FD724_RS18180	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FD724_RS18185	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FD724_RS18195	COG0003	Pfam Anion-transporting ATPase
FD724_RS18200	COG5001	Diguanylate cyclase
FD724_RS18200	COG4251	negative regulation of phosphorylation
FD724_RS18200	COG3706	GGDEF domain
FD724_RS18200	COG2203	Gaf domain
FD724_RS18200	COG5001	Diguanylate cyclase
FD724_RS18200	COG4251	negative regulation of phosphorylation
FD724_RS18200	COG3706	GGDEF domain
FD724_RS18200	COG2203	Gaf domain
FD724_RS18230	COG0745	RESPONSE REGULATOR receiver
FD724_RS18255	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FD724_RS18260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FD724_RS18265	COG0573	inorganic phosphate transmembrane transporter activity
FD724_RS18270	COG0581	inorganic phosphate transmembrane transporter activity
FD724_RS18275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FD724_RS18295	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FD724_RS18295	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FD724_RS18310	COG2119	membrane
FD724_RS18325	COG2205	protein histidine kinase activity
FD724_RS18345	COG5002	protein histidine kinase activity
FD724_RS18350	COG0745	RESPONSE REGULATOR receiver
FD724_RS18360	COG0667	Aldo Keto reductase
FD724_RS18380	COG2815	serine threonine protein kinase
FD724_RS18380	COG0515	serine threonine protein kinase
FD724_RS18390	COG0438	transferase activity, transferring glycosyl groups
FD724_RS18420	COG1215	transferase activity, transferring glycosyl groups
FD724_RS18515	COG0110	maltose O-acetyltransferase activity
FD724_RS18530	COG2971	BadF BadG BcrA BcrD
FD724_RS18535	COG2814	Major facilitator Superfamily
FD724_RS18545	COG0525	valine-tRNA ligase activity
FD724_RS18570	COG1070	Carbohydrate kinase
FD724_RS18595	COG0625	glutathione transferase activity
FD724_RS18600	COG1666	GTP binding
FD724_RS18620	COG0857	belongs to the CobB CobQ family
FD724_RS18645	COG1446	asparaginase
FD724_RS18650	COG0038	chloride channel
FD724_RS18685	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FD724_RS18690	COG3118	belongs to the thioredoxin family
FD724_RS18740	COG2226	methyltransferase
FD724_RS18750	COG0174	glutamine synthetase
FD724_RS18795	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FD724_RS18800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FD724_RS18805	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FD724_RS18810	COG4208	sulfate ABC transporter
FD724_RS18815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FD724_RS18845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FD724_RS18855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD724_RS18860	COG1045	serine acetyltransferase
FD724_RS18865	COG1959	2 iron, 2 sulfur cluster binding
FD724_RS18870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FD724_RS18885	COG0730	response to heat
FD724_RS18890	COG1309	transcriptional regulator
FD724_RS18905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FD724_RS18905	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FD724_RS18910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FD724_RS18920	COG0697	spore germination
FD724_RS18925	COG3409	Peptidoglycan-binding domain 1 protein
FD724_RS18925	COG3773	Cell wall hydrolase
FD724_RS18935	COG0004	ammonium transporteR
FD724_RS18940	COG0386	Belongs to the glutathione peroxidase family
FD724_RS18955	COG0678	peroxiredoxin activity
FD724_RS18955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FD724_RS18970	COG0671	phosphoesterase, PA-phosphatase related
FD724_RS19000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FD724_RS19010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FD724_RS19025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FD724_RS19025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FD724_RS19055	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FD724_RS19060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS19065	COG0737	Belongs to the 5'-nucleotidase family
FD724_RS19130	COG1846	Transcriptional regulator
FD724_RS19145	COG0497	DNA recombination
FD724_RS19150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FD724_RS19165	COG1132	(ABC) transporter
FD724_RS19170	COG1132	(ABC) transporter
FD724_RS19180	COG1598	PFAM Uncharacterised protein family UPF0150
FD724_RS19195	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
FD724_RS19215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FD724_RS19220	COG3854	ATPases associated with a variety of cellular activities
FD724_RS19240	COG5001	Diguanylate cyclase
FD724_RS19240	COG5002	protein histidine kinase activity
FD724_RS19240	COG3447	MASE1 domain protein
FD724_RS19245	COG2205	protein histidine kinase activity
FD724_RS19260	COG3300	MHYT domain
FD724_RS19260	COG5001	Diguanylate cyclase
FD724_RS19265	COG5002	protein histidine kinase activity
FD724_RS19265	COG0784	Response regulator, receiver
FD724_RS19275	COG0681	Belongs to the peptidase S26 family
FD724_RS19280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FD724_RS19290	COG0802	atpase or kinase
FD724_RS19295	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FD724_RS19300	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FD724_RS19310	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS19315	COG1904	glucuronate isomerase
FD724_RS19320	COG1609	Transcriptional regulator
FD724_RS19325	COG3265	gluconokinase activity
FD724_RS19340	COG1879	ABC-type sugar transport system periplasmic component
FD724_RS19345	COG1879	ABC-type sugar transport system periplasmic component
FD724_RS19350	COG1129	ABC transporter
FD724_RS19355	COG1172	Belongs to the binding-protein-dependent transport system permease family
FD724_RS19360	COG0477	Major facilitator Superfamily
FD724_RS19365	COG0673	inositol 2-dehydrogenase activity
FD724_RS19370	COG3659	wide pore channel activity
FD724_RS19390	COG0745	RESPONSE REGULATOR receiver
FD724_RS19400	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FD724_RS19405	COG2203	Gaf domain
FD724_RS19405	COG3706	GGDEF domain
FD724_RS19405	COG5001	Diguanylate cyclase
FD724_RS19405	COG4251	negative regulation of phosphorylation
FD724_RS19425	COG3266	domain, Protein
FD724_RS19425	COG0515	serine threonine protein kinase
FD724_RS19450	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FD724_RS19465	COG0028	Belongs to the TPP enzyme family
FD724_RS19470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD724_RS19475	COG3240	lipase activity
FD724_RS19480	COG2319	Wd-40 repeat
FD724_RS19480	COG3903	Transcriptional regulator
FD724_RS19495	COG1012	belongs to the aldehyde dehydrogenase family
FD724_RS19510	COG1413	lyase activity
FD724_RS19515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FD724_RS19520	COG0237	dephospho-CoA kinase activity
FD724_RS19550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FD724_RS19555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD724_RS19580	COG2197	response regulator
FD724_RS19590	COG2897	thiosulfate sulfurtransferase activity
FD724_RS19595	COG1994	Peptidase M50
FD724_RS19595	COG0517	IMP dehydrogenase activity
FD724_RS19600	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FD724_RS19605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FD724_RS19615	COG0121	glutamine amidotransferase
FD724_RS19620	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FD724_RS19630	COG1160	GTP binding
FD724_RS19660	COG1121	(ABC) transporter
FD724_RS19665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FD724_RS19670	COG0723	plastoquinol--plastocyanin reductase activity
FD724_RS19685	COG1505	serine-type exopeptidase activity
FD724_RS19690	COG2226	methyltransferase
FD724_RS19695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FD724_RS19705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FD724_RS19730	COG0606	chelatase, subunit chli
FD724_RS19740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FD724_RS19755	COG1716	ATPase activity
FD724_RS19760	COG0363	glucosamine-6-phosphate deaminase activity
FD724_RS19765	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FD724_RS19770	COG0563	adenylate kinase activity
FD724_RS19780	COG0717	Belongs to the dCTP deaminase family
FD724_RS19790	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FD724_RS19815	COG0725	ABC transporter, periplasmic molybdate-binding protein
FD724_RS19820	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FD724_RS19825	COG1489	DNA binding
FD724_RS19845	COG1032	radical SAM domain protein
FD724_RS19850	COG0702	epimerase
FD724_RS19855	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FD724_RS19895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FD724_RS19920	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FD724_RS19925	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FD724_RS19940	COG1192	Involved in chromosome partitioning
FD724_RS19945	COG2124	cytochrome p450
FD724_RS19955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FD724_RS19965	COG1132	(ABC) transporter
FD724_RS19970	COG0659	secondary active sulfate transmembrane transporter activity
FD724_RS19980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FD724_RS19985	COG0435	Glutathione S-transferase
FD724_RS19990	COG3608	succinylglutamate desuccinylase aspartoacylase
FD724_RS20005	COG0443	Heat shock 70 kDa protein
FD724_RS20050	COG3956	TIGRFAM MazG family protein
FD724_RS20055	COG1902	pentaerythritol trinitrate reductase activity
FD724_RS20065	COG2954	triphosphatase activity
FD724_RS20080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FD724_RS20085	COG1063	alcohol dehydrogenase
FD724_RS20120	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FD724_RS20130	COG0542	response to heat
FD724_RS20145	COG0628	permease
FD724_RS20150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FD724_RS20150	COG0284	orotidine-5'-phosphate decarboxylase activity
FD724_RS20170	COG2205	protein histidine kinase activity
FD724_RS20180	COG0358	DNA primase activity
FD724_RS20190	COG0784	Response regulator, receiver
FD724_RS20190	COG2205	protein histidine kinase activity
FD724_RS20190	COG5002	protein histidine kinase activity
FD724_RS20200	COG5002	protein histidine kinase activity
FD724_RS20220	COG0513	Belongs to the DEAD box helicase family
FD724_RS20225	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FD724_RS20245	COG1136	(ABC) transporter
FD724_RS20250	COG2319	Wd-40 repeat
FD724_RS20250	COG3903	Transcriptional regulator
FD724_RS20275	COG2843	Capsule synthesis protein
FD724_RS20290	COG2815	serine threonine protein kinase
FD724_RS20290	COG0515	serine threonine protein kinase
FD724_RS20295	COG3266	domain, Protein
FD724_RS20295	COG0515	serine threonine protein kinase
FD724_RS20320	COG3001	Fructosamine kinase
FD724_RS20325	COG0612	Peptidase, M16
FD724_RS20335	COG0501	Belongs to the peptidase M48B family
FD724_RS20360	COG0436	Aminotransferase
FD724_RS20365	COG1252	NADH dehydrogenase
FD724_RS20375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FD724_RS20410	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FD724_RS20415	COG1185	polyribonucleotide nucleotidyltransferase activity
FD724_RS20425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FD724_RS20430	COG4279	zinc finger
FD724_RS20460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FD724_RS20465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FD724_RS20470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FD724_RS20475	COG0673	inositol 2-dehydrogenase activity
FD724_RS20480	COG5592	hemerythrin HHE cation binding domain
FD724_RS20505	COG0850	regulation of cytokinetic process
FD724_RS20510	COG2894	cell division
FD724_RS20515	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FD724_RS20525	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FD724_RS20535	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FD724_RS20535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD724_RS20540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FD724_RS20550	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FD724_RS20560	COG0429	hydrolase of the alpha beta-hydrolase fold
FD724_RS20565	COG0745	RESPONSE REGULATOR receiver
FD724_RS20585	COG3046	protein related to deoxyribodipyrimidine photolyase
FD724_RS20605	COG3228	Belongs to the MtfA family
FD724_RS20615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FD724_RS20625	COG1846	Transcriptional regulator
FD724_RS20645	COG4636	protein conserved in cyanobacteria
FD724_RS20670	COG1295	ribonuclease BN
FD724_RS20700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FD724_RS20710	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS20725	COG5002	protein histidine kinase activity
FD724_RS20725	COG0784	Response regulator, receiver
FD724_RS20730	COG1216	Glycosyl transferase, family 2
FD724_RS20760	COG0297	glycogen (starch) synthase activity
FD724_RS20760	COG0438	transferase activity, transferring glycosyl groups
FD724_RS20765	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FD724_RS20775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FD724_RS20815	COG0318	PFAM AMP-dependent synthetase and ligase
FD724_RS20820	COG2986	histidine ammonia-lyase
FD724_RS20840	COG4935	Belongs to the peptidase S8 family
FD724_RS20840	COG1404	Belongs to the peptidase S8 family
FD724_RS20845	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FD724_RS20875	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FD724_RS20885	COG4221	oxidoreductase activity
FD724_RS20890	COG2814	Major facilitator Superfamily
FD724_RS20910	COG1215	transferase activity, transferring glycosyl groups
FD724_RS20930	COG5002	protein histidine kinase activity
FD724_RS20935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FD724_RS20935	COG0512	Glutamine amidotransferase of anthranilate synthase
FD724_RS20940	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FD724_RS20950	COG0644	oxidoreductase
FD724_RS20955	COG0277	FAD linked oxidase domain protein
FD724_RS20975	COG0024	Methionine aminopeptidase
FD724_RS20980	COG0673	inositol 2-dehydrogenase activity
FD724_RS20990	COG2385	sporulation resulting in formation of a cellular spore
FD724_RS20990	COG2385	sporulation resulting in formation of a cellular spore
FD724_RS21000	COG0783	Belongs to the Dps family
FD724_RS21010	COG1366	Belongs to the anti-sigma-factor antagonist family
FD724_RS21015	COG0745	RESPONSE REGULATOR receiver
FD724_RS21030	COG0501	Belongs to the peptidase M48B family
FD724_RS21035	COG1704	LemA family
FD724_RS21045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FD724_RS21070	COG0129	dihydroxy-acid dehydratase activity
FD724_RS21085	COG2815	serine threonine protein kinase
FD724_RS21085	COG0515	serine threonine protein kinase
FD724_RS21100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FD724_RS21120	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FD724_RS21130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FD724_RS21140	COG1051	belongs to the nudix hydrolase family
FD724_RS21145	COG0628	permease
FD724_RS21150	COG3852	Histidine kinase
FD724_RS21200	COG2124	cytochrome p450
FD724_RS21205	COG2124	cytochrome p450
FD724_RS21225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD724_RS21235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FD724_RS21235	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FD724_RS21240	COG0509	glycine decarboxylation via glycine cleavage system
FD724_RS21245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FD724_RS21250	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS21280	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FD724_RS21290	COG1803	Methylglyoxal synthase
FD724_RS21290	COG1597	lipid kinase activity
FD724_RS21330	COG3706	GGDEF domain
FD724_RS21330	COG2203	Gaf domain
FD724_RS21330	COG4251	negative regulation of phosphorylation
FD724_RS21330	COG5001	Diguanylate cyclase
FD724_RS21335	COG0181	hydroxymethylbilane synthase activity
FD724_RS21340	COG0297	glycogen (starch) synthase activity
FD724_RS21395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FD724_RS21400	COG0564	pseudouridine synthase activity
FD724_RS21420	COG2066	Belongs to the glutaminase family
FD724_RS21430	COG2885	chlorophyll binding
FD724_RS21435	COG2885	chlorophyll binding
FD724_RS21465	COG1606	tRNA processing
FD724_RS21470	COG0784	Response regulator, receiver
FD724_RS21470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FD724_RS21470	COG2205	protein histidine kinase activity
FD724_RS21470	COG2198	Histidine kinase
FD724_RS21485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FD724_RS21490	COG0745	RESPONSE REGULATOR receiver
FD724_RS21495	COG0515	serine threonine protein kinase
FD724_RS21500	COG2124	cytochrome p450
FD724_RS21505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD724_RS21520	COG3852	Histidine kinase
FD724_RS21525	COG1007	ATP synthesis coupled electron transport
FD724_RS21545	COG0523	cobalamin synthesis protein
FD724_RS21555	COG2166	iron-sulfur cluster assembly
FD724_RS21570	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FD724_RS21580	COG0113	porphobilinogen synthase activity
FD724_RS21605	COG0022	dehydrogenase e1 component
FD724_RS21605	COG0508	dehydrogenase complex catalyzes the overall conversion of
FD724_RS21610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FD724_RS21615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FD724_RS21625	COG0454	-acetyltransferase
FD724_RS21640	COG2890	protein-(glutamine-N5) methyltransferase activity
FD724_RS21655	COG0454	-acetyltransferase
FD724_RS21670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FD724_RS21690	COG0194	GDP metabolic process
FD724_RS21695	COG2052	Domain of unknown function (DUF370)
FD724_RS21705	COG0284	orotidine-5'-phosphate decarboxylase activity
FD724_RS21710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FD724_RS21715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FD724_RS21740	COG0681	Belongs to the peptidase S26 family
FD724_RS21750	COG0069	glutamate synthase activity
FD724_RS21750	COG0067	glutamate synthase
FD724_RS21750	COG0070	glutamate synthase
FD724_RS21760	COG0662	Cupin 2, conserved barrel domain protein
FD724_RS21760	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FD724_RS21765	COG0316	Belongs to the HesB IscA family
FD724_RS21770	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FD724_RS21775	COG0049	tRNA binding
FD724_RS21780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FD724_RS21785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FD724_RS21790	COG0051	transcription antitermination factor activity, RNA binding
FD724_RS21795	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FD724_RS21800	COG1605	Chorismate mutase
FD724_RS21800	COG0077	Prephenate dehydratase
FD724_RS21810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FD724_RS21815	COG1530	ribonuclease E activity
FD724_RS21845	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FD724_RS21855	COG0539	negative regulation of cytoplasmic translation
FD724_RS21870	COG2770	Histidine kinase
FD724_RS21870	COG3437	response regulator, receiver
FD724_RS21900	COG0745	RESPONSE REGULATOR receiver
FD724_RS21910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FD724_RS21915	COG0271	Belongs to the BolA IbaG family
FD724_RS21935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FD724_RS21945	COG1494	fructose-1,6-bisphosphatase
FD724_RS21950	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FD724_RS21960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FD724_RS21985	COG0166	Belongs to the GPI family
FD724_RS22025	COG0039	L-malate dehydrogenase activity
FD724_RS22035	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FD724_RS22055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FD724_RS22065	COG0521	Mo-molybdopterin cofactor biosynthetic process
FD724_RS22080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FD724_RS22085	COG0149	triose-phosphate isomerase activity
FD724_RS22090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FD724_RS22095	COG0330	HflC and HflK could
FD724_RS22105	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FD724_RS22110	COG0193	aminoacyl-tRNA hydrolase activity
FD724_RS22115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FD724_RS22170	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FD724_RS22195	COG0583	DNA-binding transcription factor activity
FD724_RS22210	COG4451	ribulose bisphosphate carboxylase, small
FD724_RS22210	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FD724_RS22215	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FD724_RS22220	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FD724_RS22225	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FD724_RS22230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FD724_RS22235	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS22280	COG0469	pyruvate kinase activity
FD724_RS22335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS22345	COG0616	signal peptide processing
FD724_RS22355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FD724_RS22370	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FD724_RS22450	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FD724_RS22470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FD724_RS22475	COG0515	serine threonine protein kinase
FD724_RS22475	COG3266	domain, Protein
FD724_RS22480	COG1088	dTDP-glucose 4,6-dehydratase activity
FD724_RS22510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FD724_RS22550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FD724_RS22575	COG4658	electron transport chain
FD724_RS22615	COG3659	wide pore channel activity
FD724_RS22620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD724_RS22635	COG0704	Plays a role in the regulation of phosphate uptake
FD724_RS22640	COG5002	protein histidine kinase activity
FD724_RS22645	COG0745	RESPONSE REGULATOR receiver
FD724_RS22660	COG2205	protein histidine kinase activity
FD724_RS22660	COG2202	Pas domain
FD724_RS22665	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FD724_RS22735	COG4451	ribulose bisphosphate carboxylase, small
FD724_RS22745	COG1850	ribulose-bisphosphate carboxylase activity
FD724_RS22760	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FD724_RS22775	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FD724_RS22780	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FD724_RS22790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FD724_RS22795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FD724_RS22810	COG0123	including yeast histone deacetylase and acetoin utilization protein
FD724_RS22830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FD724_RS22835	COG0134	indole-3-glycerol-phosphate synthase activity
FD724_RS22845	COG0288	reversible hydration of carbon dioxide
FD724_RS22855	COG0023	Translation Initiation Factor
FD724_RS22860	COG0133	tryptophan synthase activity
FD724_RS22865	COG2890	protein-(glutamine-N5) methyltransferase activity
FD724_RS22875	COG2340	Cysteine-rich secretory protein family
FD724_RS22885	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FD724_RS22890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FD724_RS22900	COG0745	RESPONSE REGULATOR receiver
FD724_RS22930	COG3657	addiction module killer protein
FD724_RS22935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FD724_RS22950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FD724_RS22955	COG0745	RESPONSE REGULATOR receiver
FD724_RS22985	COG0495	leucyl-tRNA aminoacylation
FD724_RS23000	COG1595	DNA-templated transcription, initiation
FD724_RS23025	COG1136	(ABC) transporter
FD724_RS23025	COG0577	efflux transmembrane transporter activity
FD724_RS23045	COG2356	endonuclease I
FD724_RS23050	COG1132	(ABC) transporter
FD724_RS23060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FD724_RS23090	COG5002	protein histidine kinase activity
FD724_RS23095	COG2234	aminopeptidase activity
FD724_RS23150	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FD724_RS23150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FD724_RS23150	COG1013	pyruvate-flavodoxin oxidoreductase activity
FD724_RS23150	COG0674	pyruvate-flavodoxin oxidoreductase activity
FD724_RS23155	COG0784	Response regulator, receiver
FD724_RS23155	COG2205	protein histidine kinase activity
FD724_RS23185	COG1215	transferase activity, transferring glycosyl groups
FD724_RS23190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FD724_RS23190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FD724_RS23205	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FD724_RS23250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FD724_RS23255	COG0573	inorganic phosphate transmembrane transporter activity
FD724_RS23260	COG0581	inorganic phosphate transmembrane transporter activity
FD724_RS23265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FD724_RS23270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FD724_RS23280	COG4221	oxidoreductase activity
FD724_RS23285	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FD724_RS23300	COG0745	RESPONSE REGULATOR receiver
FD724_RS23320	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FD724_RS23320	COG0140	phosphoribosyl-ATP diphosphatase activity
FD724_RS23330	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FD724_RS23345	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FD724_RS23360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD724_RS23405	COG1802	Transcriptional regulator
FD724_RS23410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FD724_RS23415	COG4249	Peptidase C14 caspase catalytic subunit p20
FD724_RS23420	COG0314	molybdopterin synthase activity
FD724_RS23435	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FD724_RS23450	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS23455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FD724_RS23465	COG0515	serine threonine protein kinase
FD724_RS23465	COG2815	serine threonine protein kinase
FD724_RS23470	COG0612	Peptidase, M16
FD724_RS23475	COG0612	Peptidase, M16
FD724_RS23485	COG1950	PFAM Membrane protein of
FD724_RS23495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FD724_RS23510	COG2022	thiamine diphosphate biosynthetic process
FD724_RS23510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD724_RS23535	COG1797	cobyrinic acid a,c-diamide synthase activity
FD724_RS23555	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FD724_RS23555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FD724_RS23625	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FD724_RS23635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FD724_RS23640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FD724_RS23645	COG0750	zinc metalloprotease
FD724_RS23650	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FD724_RS23680	COG2205	protein histidine kinase activity
FD724_RS23685	COG1361	Conserved repeat domain
FD724_RS23690	COG3429	Glucose-6-phosphate dehydrogenase subunit
FD724_RS23690	COG3409	Peptidoglycan-binding domain 1 protein
FD724_RS23695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FD724_RS23700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FD724_RS23705	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FD724_RS23740	COG2217	Heavy metal translocating P-type atpase
FD724_RS23760	COG0297	glycogen (starch) synthase activity
FD724_RS23770	COG0751	glycine-tRNA ligase activity
FD724_RS23775	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FD724_RS23785	COG0018	arginyl-trna synthetase
FD724_RS23820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FD724_RS23830	COG0730	response to heat
FD724_RS23835	COG2197	response regulator
FD724_RS23840	COG3852	Histidine kinase
FD724_RS23860	COG0701	Predicted permease
FD724_RS23895	COG0686	Belongs to the AlaDH PNT family
FD724_RS23915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FD724_RS23940	COG1309	transcriptional regulator
FD724_RS23955	COG0352	thiamine-phosphate diphosphorylase activity
FD724_RS23985	COG0110	maltose O-acetyltransferase activity
FD724_RS23990	COG3447	MASE1 domain protein
FD724_RS23990	COG5002	protein histidine kinase activity
FD724_RS23990	COG5001	Diguanylate cyclase
FD724_RS23995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FD724_RS24000	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FD724_RS24030	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FD724_RS24050	COG1842	Phage shock protein A
FD724_RS24055	COG1842	Phage shock protein A
FD724_RS24060	COG3118	belongs to the thioredoxin family
FD724_RS24065	COG0436	Aminotransferase
FD724_RS24080	COG0784	Response regulator, receiver
FD724_RS24090	COG0322	excinuclease ABC activity
FD724_RS24105	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FD724_RS24130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FD724_RS24135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FD724_RS24155	COG0215	cysteine-tRNA ligase activity
FD724_RS24160	COG0523	cobalamin synthesis protein
FD724_RS24165	COG0668	transmembrane transport
FD724_RS24180	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FD724_RS24185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FD724_RS24195	COG0515	serine threonine protein kinase
FD724_RS24215	COG2124	cytochrome p450
FD724_RS24225	COG2255	four-way junction helicase activity
FD724_RS24230	COG0107	imidazoleglycerol-phosphate synthase activity
FD724_RS24255	COG0475	glutathione-regulated potassium exporter activity
FD724_RS24260	COG0475	glutathione-regulated potassium exporter activity
FD724_RS24275	COG3958	Transketolase
FD724_RS24280	COG1349	DNA-binding transcription factor activity
FD724_RS24305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FD724_RS24310	COG0088	Forms part of the polypeptide exit tunnel
FD724_RS24315	COG0089	rRNA binding
FD724_RS24320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FD724_RS24325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FD724_RS24330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FD724_RS24335	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FD724_RS24340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FD724_RS24345	COG0255	Belongs to the universal ribosomal protein uL29 family
FD724_RS24350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FD724_RS24355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FD724_RS24360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FD724_RS24365	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FD724_RS24370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FD724_RS24375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FD724_RS24380	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FD724_RS24385	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FD724_RS24390	COG0200	Binds to the 23S rRNA
FD724_RS24395	COG0201	protein transport
FD724_RS24400	COG0563	adenylate kinase activity
FD724_RS24405	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FD724_RS24410	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FD724_RS24415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FD724_RS24420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FD724_RS24425	COG0202	RNA polymerase activity
FD724_RS24430	COG0203	ribosomal protein L17
FD724_RS24435	COG0101	tRNA pseudouridine synthase activity
FD724_RS24445	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FD724_RS24450	COG0254	rRNA binding
FD724_RS24455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FD724_RS24495	COG0488	(ABC) transporter
FD724_RS24500	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FD724_RS24515	COG0438	transferase activity, transferring glycosyl groups
FD724_RS24525	COG1381	Involved in DNA repair and RecF pathway recombination
FD724_RS24530	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FD724_RS24540	COG0297	glycogen (starch) synthase activity
FD724_RS24545	COG0799	negative regulation of ribosome biogenesis
FD724_RS24570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FD724_RS24575	COG0602	queuosine metabolic process
FD724_RS24590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FD724_RS24595	COG4597	amino acid ABC transporter
FD724_RS24600	COG0765	amino acid transport
FD724_RS24610	COG1126	abc transporter atp-binding protein
FD724_RS24650	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS24660	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FD724_RS24680	COG0542	response to heat
FD724_RS24695	COG1773	rubredoxin
FD724_RS24700	COG2081	HI0933 family
FD724_RS24705	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FD724_RS24740	COG4399	Belongs to the UPF0754 family
FD724_RS24745	COG2226	methyltransferase
FD724_RS24750	COG2204	response regulator
FD724_RS24760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD724_RS24765	COG1074	ATP-dependent DNA helicase activity
FD724_RS24795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FD724_RS24820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FD724_RS24830	COG3842	ATPase activity
FD724_RS24835	COG0768	penicillin binding
FD724_RS24840	COG0768	penicillin binding
FD724_RS24855	COG1214	PFAM Peptidase M22, glycoprotease
FD724_RS24865	COG0617	tRNA 3'-terminal CCA addition
FD724_RS24890	COG0351	phosphomethylpyrimidine kinase
FD724_RS24900	COG0347	Belongs to the P(II) protein family
FD724_RS24905	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FD724_RS24940	COG0586	Pfam SNARE associated Golgi protein
FD724_RS24945	COG0673	inositol 2-dehydrogenase activity
FD724_RS24950	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FD724_RS24955	COG1253	flavin adenine dinucleotide binding
FD724_RS24975	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FD724_RS24985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FD724_RS24990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FD724_RS25010	COG4636	protein conserved in cyanobacteria
FD724_RS25050	COG2337	Toxic component of a toxin-antitoxin (TA) module
FD724_RS25065	COG2223	nitrite transmembrane transporter activity
FD724_RS25080	COG0456	acetyltransferase
FD724_RS25125	COG1968	undecaprenyl-diphosphatase activity
FD724_RS25135	COG1555	photosystem II stabilization
FD724_RS25140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FD724_RS25160	COG4243	Vitamin k epoxide reductase
FD724_RS25165	COG0434	BtpA family
FD724_RS25170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FD724_RS25175	COG0513	Belongs to the DEAD box helicase family
FD724_RS25220	COG2211	Major facilitator Superfamily
FD724_RS25225	COG0483	inositol monophosphate 1-phosphatase activity
FD724_RS25245	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FD724_RS25260	COG0003	Pfam Anion-transporting ATPase
FD724_RS25280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FD724_RS25285	COG0438	transferase activity, transferring glycosyl groups
FD724_RS25285	COG1216	Glycosyl transferase, family 2
FD724_RS25295	COG0463	Glycosyl transferase, family 2
FD724_RS25300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD724_RS25335	COG0438	transferase activity, transferring glycosyl groups
FD724_RS25350	COG1091	dTDP-4-dehydrorhamnose reductase activity
FD724_RS25355	COG2045	Belongs to the ComB family
FD724_RS25390	COG3688	RNA-binding protein containing a PIN domain
FD724_RS25395	COG1122	ATPase activity
FD724_RS25410	COG2154	pterin-4-alpha-carbinolamine dehydratase
FD724_RS25415	COG3659	wide pore channel activity
FD724_RS25425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FD724_RS25435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FD724_RS25440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FD724_RS25445	COG2048	Heterodisulfide reductase, subunit B
FD724_RS25505	COG1480	7TM receptor with intracellular HD hydrolase
FD724_RS25515	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FD724_RS25525	COG1754	DNA topoisomerase type I activity
FD724_RS25525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FD724_RS25540	COG3659	wide pore channel activity
FD724_RS25545	COG3443	Belongs to the bacterial solute-binding protein 9 family
FD724_RS25545	COG0803	Belongs to the bacterial solute-binding protein 9 family
FD724_RS25550	COG1121	(ABC) transporter
FD724_RS25555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FD724_RS25575	COG0438	transferase activity, transferring glycosyl groups
FD724_RS25590	COG3546	catalase activity
FD724_RS25595	COG2261	transglycosylase associated protein
FD724_RS25600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FD724_RS25605	COG5398	heme oxygenase
FD724_RS25660	COG0318	PFAM AMP-dependent synthetase and ligase
FD724_RS25665	COG0598	Magnesium transport protein CorA
FD724_RS25670	COG0515	serine threonine protein kinase
FD724_RS25670	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS25680	COG0527	aspartate kinase activity
FD724_RS25685	COG4636	protein conserved in cyanobacteria
FD724_RS25720	COG0392	lysyltransferase activity
FD724_RS25735	COG0392	lysyltransferase activity
FD724_RS25735	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FD724_RS25755	COG1994	Peptidase M50
FD724_RS25765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FD724_RS25785	COG0411	ABC transporter
FD724_RS25805	COG2124	cytochrome p450
FD724_RS25815	COG0586	Pfam SNARE associated Golgi protein
FD724_RS25820	COG3932	Exopolysaccharide synthesis, ExoD
FD724_RS25840	COG1012	belongs to the aldehyde dehydrogenase family
FD724_RS25880	COG0540	Belongs to the ATCase OTCase family
FD724_RS25885	COG2239	Acts as a magnesium transporter
FD724_RS25930	COG0811	peptide transport
FD724_RS25935	COG0848	biopolymer transport protein
FD724_RS25970	COG0408	coproporphyrinogen oxidase activity
FD724_RS25980	COG0489	protein tyrosine kinase activity
FD724_RS25985	COG0772	Belongs to the SEDS family
FD724_RS26000	COG0589	response to stress
FD724_RS26000	COG0475	glutathione-regulated potassium exporter activity
FD724_RS26005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD724_RS26010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FD724_RS26045	COG1546	Belongs to the CinA family
FD724_RS26045	COG1058	Belongs to the CinA family
FD724_RS26050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FD724_RS26065	COG0612	Peptidase, M16
FD724_RS26075	COG4251	negative regulation of phosphorylation
FD724_RS26090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FD724_RS26120	COG0667	Aldo Keto reductase
FD724_RS26135	COG1063	alcohol dehydrogenase
FD724_RS26150	COG0456	acetyltransferase
FD724_RS26180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FD724_RS26185	COG2205	protein histidine kinase activity
FD724_RS26215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FD724_RS26240	COG0747	negative chemotaxis
FD724_RS26270	COG0539	negative regulation of cytoplasmic translation
FD724_RS26295	COG4178	(ABC) transporter
FD724_RS26300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FD724_RS26330	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FD724_RS26335	COG0473	3-isopropylmalate dehydrogenase activity
FD724_RS26340	COG3621	Patatin-like phospholipase
FD724_RS26345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FD724_RS26345	COG0300	oxidoreductase activity
FD724_RS26345	COG3321	synthase
FD724_RS26345	COG0318	PFAM AMP-dependent synthetase and ligase
FD724_RS26345	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS26355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FD724_RS26370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FD724_RS26395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FD724_RS26440	COG0489	protein tyrosine kinase activity
FD724_RS26465	COG1470	cell adhesion involved in biofilm formation
FD724_RS26465	COG1388	LysM domain
FD724_RS26495	COG0667	Aldo Keto reductase
FD724_RS26510	COG0438	transferase activity, transferring glycosyl groups
FD724_RS26530	COG0463	Glycosyl transferase, family 2
FD724_RS26540	COG0297	glycogen (starch) synthase activity
FD724_RS26565	COG0297	glycogen (starch) synthase activity
FD724_RS26570	COG0367	asparagine synthase
FD724_RS26575	COG0297	glycogen (starch) synthase activity
FD724_RS26605	COG1216	Glycosyl transferase, family 2
FD724_RS26610	COG0398	Pfam SNARE associated Golgi protein
FD724_RS26615	COG0398	Pfam SNARE associated Golgi protein
FD724_RS26620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FD724_RS26625	COG5183	chlorophyll binding
FD724_RS26625	COG2133	pyrroloquinoline quinone binding
FD724_RS26635	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS26645	COG0515	serine threonine protein kinase
FD724_RS26655	COG1222	aaa ATPase
FD724_RS26680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FD724_RS26740	COG0438	transferase activity, transferring glycosyl groups
FD724_RS26745	COG0438	transferase activity, transferring glycosyl groups
FD724_RS26755	COG2988	succinylglutamate desuccinylase activity
FD724_RS26785	COG0151	Belongs to the GarS family
FD724_RS26815	COG1201	RNA secondary structure unwinding
FD724_RS26820	COG3386	PFAM SMP-30 Gluconolaconase
FD724_RS26840	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FD724_RS26845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD724_RS26850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FD724_RS26860	COG0395	ABC-type sugar transport system, permease component
FD724_RS26865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FD724_RS26875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD724_RS26885	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FD724_RS26910	COG0826	peptidase U32
FD724_RS26925	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FD724_RS26925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FD724_RS26930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FD724_RS26935	COG0148	phosphopyruvate hydratase activity
FD724_RS26940	COG0346	lactoylglutathione lyase activity
FD724_RS26945	COG0542	response to heat
FD724_RS26970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FD724_RS27010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FD724_RS27015	COG0457	Tetratricopeptide repeat
FD724_RS27020	COG2135	peptidase activity
FD724_RS27025	COG0625	glutathione transferase activity
FD724_RS27030	COG1872	DUF167
FD724_RS27055	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FD724_RS27065	COG1845	cytochrome c oxidase, subunit III
FD724_RS27070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FD724_RS27075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FD724_RS27095	COG2205	protein histidine kinase activity
FD724_RS27095	COG0784	Response regulator, receiver
FD724_RS27115	COG0784	Response regulator, receiver
FD724_RS27115	COG2205	protein histidine kinase activity
FD724_RS27125	COG1404	Belongs to the peptidase S8 family
FD724_RS27175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FD724_RS27185	COG0784	Response regulator, receiver
FD724_RS27185	COG2205	protein histidine kinase activity
FD724_RS27195	COG4251	negative regulation of phosphorylation
FD724_RS27200	COG0784	Response regulator, receiver
FD724_RS27205	COG0156	8-amino-7-oxononanoate synthase activity
FD724_RS27210	COG0632	four-way junction helicase activity
FD724_RS27230	COG2203	Gaf domain
FD724_RS27230	COG5001	Diguanylate cyclase
FD724_RS27230	COG4251	negative regulation of phosphorylation
FD724_RS27230	COG3706	GGDEF domain
FD724_RS27250	COG2442	InterPro IPR007367
FD724_RS27255	COG4804	nuclease activity
FD724_RS27295	COG1468	defense response to virus
FD724_RS27295	COG1518	maintenance of DNA repeat elements
FD724_RS27300	COG1518	maintenance of DNA repeat elements
FD724_RS27305	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FD724_RS27310	COG2205	protein histidine kinase activity
FD724_RS27310	COG3437	response regulator, receiver
FD724_RS27310	COG3850	Histidine kinase
FD724_RS27310	COG4999	Histidine kinase
FD724_RS27320	COG1429	ligase activity, forming nitrogen-metal bonds
FD724_RS27325	COG0860	N-Acetylmuramoyl-L-alanine amidase
FD724_RS27330	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS27345	COG2815	serine threonine protein kinase
FD724_RS27345	COG0515	serine threonine protein kinase
FD724_RS27390	COG0405	Gamma-glutamyltransferase
FD724_RS27415	COG0517	IMP dehydrogenase activity
FD724_RS27415	COG1125	glycine betaine transport
FD724_RS27445	COG1487	ribonuclease activity
FD724_RS27450	COG0542	response to heat
FD724_RS27455	COG0488	(ABC) transporter
FD724_RS27470	COG1233	COG1233 Phytoene dehydrogenase and related
FD724_RS27485	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS27485	COG0515	serine threonine protein kinase
FD724_RS27490	COG1177	transmembrane transport
FD724_RS27495	COG0438	transferase activity, transferring glycosyl groups
FD724_RS27500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FD724_RS27505	COG1104	cysteine desulfurase activity
FD724_RS27560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD724_RS27570	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FD724_RS27575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FD724_RS27585	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
FD724_RS27590	COG1027	Aspartate ammonia-lyase
FD724_RS27595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FD724_RS27605	COG1619	proteins homologs of microcin C7 resistance protein MccF
FD724_RS27615	COG0460	homoserine dehydrogenase
FD724_RS27620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FD724_RS27625	COG0572	uridine kinase
FD724_RS27630	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FD724_RS27635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD724_RS27640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD724_RS27685	COG2119	membrane
FD724_RS27695	COG1053	succinate dehydrogenase
FD724_RS27720	COG1562	ergosterol biosynthetic process
FD724_RS27725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD724_RS27725	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FD724_RS27860	COG5002	protein histidine kinase activity
FD724_RS27875	COG3263	regulation of cellular component size
FD724_RS27895	COG2010	Cytochrome c
FD724_RS27900	COG3794	PFAM blue (type 1) copper domain protein
FD724_RS27905	COG2010	Cytochrome c
FD724_RS27915	COG0395	ABC-type sugar transport system, permease component
FD724_RS27950	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FD724_RS27955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FD724_RS27965	COG0473	3-isopropylmalate dehydrogenase activity
FD724_RS27970	COG0668	transmembrane transport
FD724_RS27975	COG1131	(ABC) transporter
FD724_RS27990	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FD724_RS27995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FD724_RS28000	COG0484	heat shock protein binding
FD724_RS28020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FD724_RS28020	COG0596	Alpha beta hydrolase
FD724_RS28020	COG2226	methyltransferase
FD724_RS28035	COG0308	aminopeptidase N
FD724_RS28040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FD724_RS28075	COG0438	transferase activity, transferring glycosyl groups
FD724_RS28080	COG1132	(ABC) transporter
FD724_RS28095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FD724_RS28100	COG0359	binds to the 23S rRNA
FD724_RS28105	COG1372	Participates in initiation and elongation during chromosome replication
FD724_RS28105	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS28105	COG1372	Participates in initiation and elongation during chromosome replication
FD724_RS28105	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS28170	COG0612	Peptidase, M16
FD724_RS28175	COG0612	Peptidase, M16
FD724_RS28195	COG0384	phenazine biosynthesis protein PhzF
FD724_RS28205	COG0006	proline dipeptidase activity
FD724_RS28225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FD724_RS28230	COG0228	four-way junction DNA binding
FD724_RS28240	COG1702	phosphate starvation-inducible protein PhoH
FD724_RS28260	COG1132	(ABC) transporter
FD724_RS28305	COG0339	signal peptide processing
FD724_RS28320	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FD724_RS28335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FD724_RS28340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FD724_RS28345	COG0321	lipoyl(octanoyl) transferase activity
FD724_RS28355	COG1126	abc transporter atp-binding protein
FD724_RS28360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FD724_RS28365	COG1803	Methylglyoxal synthase
FD724_RS28365	COG1597	lipid kinase activity
FD724_RS28380	COG0300	oxidoreductase activity
FD724_RS28405	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FD724_RS28410	COG4251	negative regulation of phosphorylation
FD724_RS28420	COG2205	protein histidine kinase activity
FD724_RS28450	COG0038	chloride channel
FD724_RS28460	COG1959	2 iron, 2 sulfur cluster binding
FD724_RS28465	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FD724_RS28470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FD724_RS28485	COG0784	Response regulator, receiver
FD724_RS28490	COG4251	negative regulation of phosphorylation
FD724_RS28520	COG0784	Response regulator, receiver
FD724_RS28525	COG4251	negative regulation of phosphorylation
FD724_RS28530	COG1722	exodeoxyribonuclease VII activity
FD724_RS28535	COG1570	exodeoxyribonuclease VII activity
FD724_RS28540	COG1192	Involved in chromosome partitioning
FD724_RS28555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FD724_RS28565	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS28565	COG0515	serine threonine protein kinase
FD724_RS28595	COG0430	RNA-3'-phosphate cyclase activity
FD724_RS28605	COG0438	transferase activity, transferring glycosyl groups
FD724_RS28620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FD724_RS28625	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FD724_RS28630	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FD724_RS28635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FD724_RS28640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FD724_RS28645	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FD724_RS28655	COG0667	Aldo Keto reductase
FD724_RS28675	COG1515	deoxyribonuclease V activity
FD724_RS28690	COG1429	ligase activity, forming nitrogen-metal bonds
FD724_RS28750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FD724_RS28760	COG1473	amidohydrolase
FD724_RS28765	COG1968	undecaprenyl-diphosphatase activity
FD724_RS28770	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FD724_RS28775	COG0515	serine threonine protein kinase
FD724_RS28780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FD724_RS28785	COG4999	Histidine kinase
FD724_RS28785	COG3850	Histidine kinase
FD724_RS28785	COG3437	response regulator, receiver
FD724_RS28785	COG2205	protein histidine kinase activity
FD724_RS28800	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FD724_RS28810	COG1218	3'(2'),5'-bisphosphate nucleotidase
FD724_RS28815	COG0724	RNA recognition motif
FD724_RS28830	COG1943	Transposase
FD724_RS28845	COG1011	Hydrolase
FD724_RS28855	COG0489	protein tyrosine kinase activity
FD724_RS28860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FD724_RS28865	COG3119	arylsulfatase activity
FD724_RS28905	COG1127	ABC transporter
FD724_RS28920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FD724_RS28925	COG3852	Histidine kinase
FD724_RS28930	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FD724_RS28935	COG3977	Valine--pyruvate aminotransferase
FD724_RS28940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FD724_RS28950	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FD724_RS28955	COG3693	PFAM glycoside hydrolase, family 10
FD724_RS28960	COG1289	transmembrane transporter activity
FD724_RS28970	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FD724_RS28975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD724_RS28980	COG0590	tRNA wobble adenosine to inosine editing
FD724_RS29015	COG0537	adenosine 5'-monophosphoramidase activity
FD724_RS29035	COG2197	response regulator
FD724_RS29040	COG2203	Gaf domain
FD724_RS29040	COG4585	Histidine kinase
FD724_RS29045	COG4221	oxidoreductase activity
FD724_RS29055	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FD724_RS29065	COG2197	response regulator
FD724_RS29070	COG4585	Histidine kinase
FD724_RS29090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FD724_RS29105	COG1834	amidinotransferase
FD724_RS29120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FD724_RS29130	COG0402	S-adenosylhomocysteine deaminase activity
FD724_RS29150	COG0725	ABC transporter, periplasmic molybdate-binding protein
FD724_RS29160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD724_RS29195	COG5002	protein histidine kinase activity
FD724_RS29205	COG2217	Heavy metal translocating P-type atpase
FD724_RS29220	COG0745	RESPONSE REGULATOR receiver
FD724_RS29240	COG2197	response regulator
FD724_RS29250	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FD724_RS29255	COG2130	NADP-dependent
FD724_RS29300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FD724_RS29320	COG5433	transposase activity
FD724_RS29345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FD724_RS29360	COG1192	Involved in chromosome partitioning
FD724_RS29365	COG1899	peptidyl-lysine modification to peptidyl-hypusine
FD724_RS29380	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FD724_RS29400	COG0438	transferase activity, transferring glycosyl groups
FD724_RS29420	COG1215	transferase activity, transferring glycosyl groups
FD724_RS29425	COG0489	protein tyrosine kinase activity
FD724_RS29440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FD724_RS29440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FD724_RS29480	COG1215	transferase activity, transferring glycosyl groups
FD724_RS29485	COG0793	Belongs to the peptidase S41A family
FD724_RS29495	COG1132	(ABC) transporter
FD724_RS29500	COG1132	(ABC) transporter
FD724_RS29515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD724_RS29530	COG0318	PFAM AMP-dependent synthetase and ligase
FD724_RS29565	COG2831	hemolysin activation secretion protein
FD724_RS29620	COG0243	molybdopterin cofactor binding
FD724_RS29625	COG2223	nitrite transmembrane transporter activity
FD724_RS29640	COG0723	plastoquinol--plastocyanin reductase activity
FD724_RS29650	COG1598	PFAM Uncharacterised protein family UPF0150
FD724_RS29655	COG0583	DNA-binding transcription factor activity
FD724_RS29660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FD724_RS29665	COG1316	TRANSCRIPTIONal
FD724_RS29675	COG0628	permease
FD724_RS29690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FD724_RS29715	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS29715	COG0515	serine threonine protein kinase
FD724_RS29720	COG0515	serine threonine protein kinase
FD724_RS29720	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS29725	COG5433	transposase activity
FD724_RS29745	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FD724_RS29750	COG2205	protein histidine kinase activity
FD724_RS29750	COG3437	response regulator, receiver
FD724_RS29750	COG3850	Histidine kinase
FD724_RS29750	COG4999	Histidine kinase
FD724_RS29760	COG0481	GTPase activity
FD724_RS29765	COG4251	negative regulation of phosphorylation
FD724_RS29765	COG2203	Gaf domain
FD724_RS29765	COG3706	GGDEF domain
FD724_RS29765	COG5001	Diguanylate cyclase
FD724_RS29790	COG0438	transferase activity, transferring glycosyl groups
FD724_RS29800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FD724_RS29805	COG2814	Major facilitator Superfamily
FD724_RS29810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FD724_RS29830	COG0121	glutamine amidotransferase
FD724_RS29845	COG2363	Small membrane protein
FD724_RS29855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FD724_RS29860	COG0475	glutathione-regulated potassium exporter activity
FD724_RS29860	COG0589	response to stress
FD724_RS29870	COG0419	ATPase involved in DNA repair
FD724_RS29875	COG3409	Peptidoglycan-binding domain 1 protein
FD724_RS29875	COG0860	N-Acetylmuramoyl-L-alanine amidase
FD724_RS29885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD724_RS29910	COG0706	membrane insertase activity
FD724_RS29920	COG0594	ribonuclease P activity
FD724_RS29925	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FD724_RS29970	COG3852	Histidine kinase
FD724_RS29985	COG0784	Response regulator, receiver
FD724_RS29985	COG2205	protein histidine kinase activity
FD724_RS29985	COG2198	Histidine kinase
FD724_RS30000	COG5433	transposase activity
FD724_RS30035	COG0531	amino acid
FD724_RS30045	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS30070	COG1615	UPF0182 protein
FD724_RS30075	COG0515	serine threonine protein kinase
FD724_RS30075	COG1357	PFAM Pentapeptide repeats (8 copies)
FD724_RS30090	COG0438	transferase activity, transferring glycosyl groups
FD724_RS30100	COG0312	modulator of DNA gyrase
FD724_RS30115	COG2066	Belongs to the glutaminase family
FD724_RS30125	COG1252	NADH dehydrogenase
FD724_RS30140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FD724_RS30145	COG2076	Multidrug Resistance protein
FD724_RS30150	COG0071	Belongs to the small heat shock protein (HSP20) family
FD724_RS30165	COG3210	domain, Protein
FD724_RS30180	COG0784	Response regulator, receiver
FD724_RS30180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FD724_RS30230	COG0758	DNA mediated transformation
FD724_RS30230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FD724_RS30250	COG0083	homoserine kinase activity
FD724_RS30305	COG5002	protein histidine kinase activity
FD724_RS30310	COG4953	penicillin-binding protein 1C
FD724_RS30315	COG2373	Large extracellular alpha-helical protein
FD724_RS30335	COG5002	protein histidine kinase activity
FD724_RS30345	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FD724_RS30355	COG0004	ammonium transporteR
FD724_RS30365	COG1742	UPF0060 membrane protein
FD724_RS30370	COG5002	protein histidine kinase activity
FD724_RS30370	COG0784	Response regulator, receiver
FD724_RS30370	COG2205	protein histidine kinase activity
FD724_RS30440	COG5001	Diguanylate cyclase
FD724_RS30460	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FD724_RS30475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FD724_RS30485	COG0505	Belongs to the CarA family
FD724_RS30495	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FD724_RS30500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FD724_RS30510	COG0596	Alpha beta hydrolase
FD724_RS30515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FD724_RS30525	COG5002	protein histidine kinase activity
FD724_RS30530	COG0784	Response regulator, receiver
FD724_RS30535	COG4251	negative regulation of phosphorylation
FD724_RS30540	COG2336	PFAM SpoVT AbrB
FD724_RS30555	COG0697	spore germination
FD724_RS30560	COG1858	cytochrome C peroxidase
FD724_RS30565	COG0456	acetyltransferase
FD724_RS30580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FD724_RS30600	COG0529	Catalyzes the synthesis of activated sulfate
FD724_RS30610	COG4771	TonB-dependent receptor
FD724_RS30625	COG2010	Cytochrome c
FD724_RS30630	COG0515	serine threonine protein kinase
FD724_RS30630	COG2815	serine threonine protein kinase
FD724_RS30640	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD724_RS30645	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FD724_RS30655	COG0483	inositol monophosphate 1-phosphatase activity
FD724_RS30665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FD724_RS30720	COG1845	cytochrome c oxidase, subunit III
FD724_RS30725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FD724_RS30730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FD724_RS30745	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS30765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FD724_RS30765	COG2205	protein histidine kinase activity
FD724_RS30775	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FD724_RS30785	COG3540	Alkaline phosphatase
FD724_RS30800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FD724_RS30830	COG3848	Pyruvate phosphate dikinase
FD724_RS30830	COG0574	Belongs to the PEP-utilizing enzyme family
FD724_RS30840	COG0154	amidase activity
FD724_RS30850	COG4221	oxidoreductase activity
FD724_RS30855	COG2207	Transcriptional regulator
FD724_RS30860	COG1695	Transcriptional regulator
FD724_RS30870	COG0363	glucosamine-6-phosphate deaminase activity
FD724_RS30885	COG1136	(ABC) transporter
FD724_RS30910	COG0604	alcohol dehydrogenase
FD724_RS30910	COG3321	synthase
FD724_RS30915	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS30915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FD724_RS30915	COG3321	synthase
FD724_RS30915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD724_RS30915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FD724_RS30920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FD724_RS30920	COG2070	2-Nitropropane dioxygenase
FD724_RS30935	COG3320	Male sterility
FD724_RS30935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FD724_RS30960	COG5001	Diguanylate cyclase
FD724_RS30960	COG3447	MASE1 domain protein
FD724_RS30960	COG5002	protein histidine kinase activity
FD724_RS30965	COG5002	protein histidine kinase activity
FD724_RS30970	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FD724_RS30985	COG0784	Response regulator, receiver
FD724_RS30985	COG2205	protein histidine kinase activity
FD724_RS31020	COG0297	glycogen (starch) synthase activity
FD724_RS31025	COG1605	Chorismate mutase
FD724_RS31025	COG0287	Prephenate dehydrogenase
FD724_RS31035	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FD724_RS31040	COG0512	Glutamine amidotransferase of anthranilate synthase
FD724_RS31040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FD724_RS31045	COG0134	indole-3-glycerol-phosphate synthase activity
FD724_RS31055	COG0159	tryptophan synthase activity
FD724_RS31060	COG0133	tryptophan synthase activity
FD724_RS31065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FD724_RS31070	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FD724_RS31085	COG0300	oxidoreductase activity
FD724_RS31095	COG0515	serine threonine protein kinase
FD724_RS31100	COG0515	serine threonine protein kinase
FD724_RS31100	COG3266	domain, Protein
FD724_RS31110	COG0038	chloride channel
FD724_RS31130	COG2258	MOSC domain
FD724_RS31155	COG1304	FMN binding
FD724_RS31160	COG0616	signal peptide processing
FD724_RS31165	COG4638	Rieske (2fe-2S)
FD724_RS31175	COG4191	Histidine kinase
FD724_RS31205	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FD724_RS31210	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FD724_RS31270	COG1649	PFAM Uncharacterised BCR, COG1649
FD724_RS31280	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS31285	COG1773	rubredoxin
FD724_RS31300	COG0330	HflC and HflK could
FD724_RS31315	COG0735	belongs to the Fur family
FD724_RS31320	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FD724_RS31325	COG0047	phosphoribosylformylglycinamidine synthase activity
FD724_RS31330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD724_RS31335	COG2274	protein secretion by the type I secretion system
FD724_RS31355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FD724_RS31355	COG2755	lipolytic protein G-D-S-L family
FD724_RS31375	COG0584	glycerophosphoryl diester phosphodiesterase
FD724_RS31415	COG4948	Mandelate Racemase Muconate Lactonizing
FD724_RS31445	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FD724_RS31450	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FD724_RS31465	COG1672	PFAM Archaeal ATPase
FD724_RS31465	COG2319	Wd-40 repeat
FD724_RS31500	COG4636	protein conserved in cyanobacteria
FD724_RS31515	COG0159	tryptophan synthase activity
FD724_RS31525	COG3266	domain, Protein
FD724_RS31525	COG0515	serine threonine protein kinase
FD724_RS31540	COG1181	Belongs to the D-alanine--D-alanine ligase family
FD724_RS31550	COG0242	peptide deformylase activity
FD724_RS31555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD724_RS31575	COG0776	regulation of translation
FD724_RS31710	COG4636	protein conserved in cyanobacteria
FD724_RS31785	COG2319	Wd-40 repeat
FD724_RS31785	COG1672	PFAM Archaeal ATPase
FD724_RS31790	COG1672	PFAM Archaeal ATPase
FD724_RS31790	COG2319	Wd-40 repeat
FD724_RS31820	COG2226	methyltransferase
FD724_RS31915	COG0300	oxidoreductase activity
FD724_RS31985	COG2267	carboxylic ester hydrolase activity
FD724_RS32020	COG2226	methyltransferase
FD724_RS32040	COG2385	sporulation resulting in formation of a cellular spore
FD724_RS32075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FD724_RS32080	COG1475	DNA binding
FD724_RS32085	COG1192	Involved in chromosome partitioning
FD724_RS32255	COG4974	Belongs to the 'phage' integrase family
FD724_RS32265	COG3903	Transcriptional regulator
FD724_RS32265	COG2319	Wd-40 repeat
FD724_RS32290	COG1819	glycosyl
FD724_RS32300	COG4243	Vitamin k epoxide reductase
FD724_RS32395	COG0505	Belongs to the CarA family
FD724_RS32420	COG2258	MOSC domain
FD724_RS32430	COG4941	Belongs to the sigma-70 factor family
FD724_RS32435	COG3795	YCII-related domain
FD724_RS32455	COG0625	glutathione transferase activity
FD724_RS32495	COG1819	glycosyl
FD724_RS32545	COG0270	DNA (cytosine-5-)-methyltransferase activity
FD724_RS32560	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS32585	COG1372	Participates in initiation and elongation during chromosome replication
FD724_RS32585	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS32680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FD724_RS32685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FD724_RS32715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FD724_RS32755	COG1403	HNH endonuclease
FD724_RS32760	COG0625	glutathione transferase activity
FD724_RS32810	COG1205	dead DEAH box helicase
FD724_RS32810	COG1111	helicase
FD724_RS32850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FD724_RS32865	COG0592	DNA-directed DNA polymerase activity
FD724_RS32870	COG3831	ATPase activity
FD724_RS32875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD724_RS32905	COG3437	response regulator, receiver
FD724_RS32905	COG4999	Histidine kinase
FD724_RS32905	COG3850	Histidine kinase
FD724_RS32905	COG2205	protein histidine kinase activity
FD724_RS32910	COG0539	negative regulation of cytoplasmic translation
FD724_RS32975	COG2198	Histidine kinase
FD724_RS32975	COG2205	protein histidine kinase activity
FD724_RS32975	COG0784	Response regulator, receiver
FD724_RS32980	COG2197	response regulator
FD724_RS33095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD724_RS33115	COG1192	Involved in chromosome partitioning
FD724_RS33160	COG0745	RESPONSE REGULATOR receiver
FD724_RS33175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FD724_RS33180	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FD724_RS33185	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FD724_RS33190	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FD724_RS33195	COG2080	2 iron, 2 sulfur cluster binding
FD724_RS33215	COG0542	response to heat
FD724_RS33225	COG0484	heat shock protein binding
FD724_RS33245	COG0656	L-ascorbic acid biosynthetic process
FD724_RS33250	COG3548	integral membrane protein
FD724_RS33265	COG4572	Cation transport regulator
FD724_RS33270	COG0443	Heat shock 70 kDa protein
FD724_RS33275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FD724_RS33275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FD724_RS33295	COG0459	protein refolding
FD724_RS33340	COG1902	pentaerythritol trinitrate reductase activity
FD724_RS33365	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FD724_RS33445	COG0582	viral genome integration into host DNA
FD724_RS33480	COG0675	Transposase, IS605 OrfB family
FD724_RS33485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD724_RS33535	COG4804	nuclease activity
FD724_RS33545	COG1192	Involved in chromosome partitioning
FD724_RS33555	COG3629	intracellular signal transduction
FD724_RS33555	COG3903	Transcriptional regulator
FD724_RS33580	COG5433	transposase activity
FD724_RS33615	COG1902	pentaerythritol trinitrate reductase activity
FD724_RS33625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FD724_RS33695	COG1475	DNA binding
FD724_RS33700	COG1192	Involved in chromosome partitioning
FD724_RS33705	COG4804	nuclease activity
FD724_RS33745	COG2197	response regulator
FD724_RS33820	COG3437	response regulator, receiver
FD724_RS33845	COG1942	4-Oxalocrotonate Tautomerase
FD724_RS33850	COG0582	viral genome integration into host DNA
FD724_RS33970	COG1487	ribonuclease activity
FD724_RS33990	COG1061	Type III restriction enzyme res subunit
FD724_RS33995	COG0582	viral genome integration into host DNA
FD724_RS34010	COG2197	response regulator
FD724_RS34155	COG3609	addiction module antidote protein, CC2985 family
FD724_RS34180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS34180	COG1116	anion transmembrane transporter activity
FD724_RS34185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD724_RS34295	COG4974	Belongs to the 'phage' integrase family
FD724_RS34340	COG0318	PFAM AMP-dependent synthetase and ligase
FD724_RS34345	COG1309	transcriptional regulator
FD724_RS34355	COG0583	DNA-binding transcription factor activity
FD724_RS34370	COG3657	addiction module killer protein
FD724_RS34380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FD724_RS34390	COG1192	Involved in chromosome partitioning
FD724_RS34395	COG1475	DNA binding
FD724_RS34400	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FD724_RS34400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FD724_RS34410	COG2815	serine threonine protein kinase
FD724_RS34410	COG0515	serine threonine protein kinase
FD724_RS34415	COG2988	succinylglutamate desuccinylase activity
FD724_RS34455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FD724_RS34455	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FD724_RS34600	COG1192	Involved in chromosome partitioning
FD724_RS34605	COG1475	DNA binding
FD724_RS34635	COG2831	hemolysin activation secretion protein
FD724_RS34665	COG4974	Belongs to the 'phage' integrase family
FD724_RS34670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FD724_RS34700	COG5433	transposase activity
FD724_RS34770	COG1192	Involved in chromosome partitioning
FD724_RS34775	COG1475	DNA binding
FD724_RS34805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FD724_RS34815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FD724_RS34870	COG2197	response regulator
FD724_RS34880	COG1252	NADH dehydrogenase
FD724_RS34895	COG1830	Aldolase
FD724_RS34900	COG1275	C4-dicarboxylate transporter malic acid transport protein
FD724_RS34910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FD724_RS34935	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS34950	COG2072	flavoprotein involved in K transport
FD724_RS34965	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS34985	COG0783	Belongs to the Dps family
FD724_RS34995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FD724_RS34995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FD724_RS35000	COG2197	response regulator
FD724_RS35005	COG4585	Histidine kinase
FD724_RS35015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FD724_RS35015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FD724_RS35020	COG2197	response regulator
FD724_RS35025	COG2815	serine threonine protein kinase
FD724_RS35025	COG0515	serine threonine protein kinase
FD724_RS35125	COG1372	Participates in initiation and elongation during chromosome replication
FD724_RS35125	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS35130	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS35195	COG2274	protein secretion by the type I secretion system
FD724_RS35245	COG0535	radical SAM domain protein
FD724_RS35265	COG0489	protein tyrosine kinase activity
FD724_RS35280	COG3292	Two component regulator propeller
FD724_RS35280	COG0745	RESPONSE REGULATOR receiver
FD724_RS35280	COG2205	protein histidine kinase activity
FD724_RS35285	COG0745	RESPONSE REGULATOR receiver
FD724_RS35290	COG5002	protein histidine kinase activity
FD724_RS35305	COG2205	protein histidine kinase activity
FD724_RS35385	COG0534	Mate efflux family protein
FD724_RS35425	COG0300	oxidoreductase activity
FD724_RS35435	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FD724_RS35450	COG0776	regulation of translation
FD724_RS35515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FD724_RS35645	COG2815	serine threonine protein kinase
FD724_RS35645	COG0515	serine threonine protein kinase
FD724_RS35650	COG0784	Response regulator, receiver
FD724_RS35650	COG3437	response regulator, receiver
FD724_RS35665	COG3511	phospholipase C
FD724_RS35720	COG2304	oxidoreductase activity
FD724_RS35730	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS35775	COG2217	Heavy metal translocating P-type atpase
FD724_RS35835	COG0745	RESPONSE REGULATOR receiver
FD724_RS35840	COG5002	protein histidine kinase activity
FD724_RS35850	COG3046	protein related to deoxyribodipyrimidine photolyase
FD724_RS35885	COG0640	Transcriptional regulator
FD724_RS35905	COG1017	nitric oxide dioxygenase activity
FD724_RS35905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FD724_RS35945	COG0783	Belongs to the Dps family
FD724_RS35955	COG0589	response to stress
FD724_RS35965	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS36070	COG0640	Transcriptional regulator
FD724_RS36160	COG0776	regulation of translation
FD724_RS36185	COG0515	serine threonine protein kinase
FD724_RS36270	COG5433	transposase activity
FD724_RS36295	COG4636	protein conserved in cyanobacteria
FD724_RS36300	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS36415	COG0300	oxidoreductase activity
FD724_RS36480	COG0626	cystathionine gamma-synthase activity
FD724_RS36490	COG0436	Aminotransferase
FD724_RS36525	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS36530	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS36545	COG1309	transcriptional regulator
FD724_RS36575	COG1845	cytochrome c oxidase, subunit III
FD724_RS36580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FD724_RS36585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FD724_RS36615	COG0778	Nitroreductase
FD724_RS36630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FD724_RS36665	COG3437	response regulator, receiver
FD724_RS36690	COG3585	molybdate ion transport
FD724_RS36695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FD724_RS36705	COG3659	wide pore channel activity
FD724_RS36710	COG0725	ABC transporter, periplasmic molybdate-binding protein
FD724_RS36715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FD724_RS36730	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FD724_RS36735	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS36740	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FD724_RS36745	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FD724_RS36750	COG1910	domain protein
FD724_RS36975	COG1192	Involved in chromosome partitioning
FD724_RS37085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FD724_RS37095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FD724_RS37175	COG1674	ftsk spoiiie
FD724_RS37200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FD724_RS37255	COG2319	Wd-40 repeat
FD724_RS37255	COG3903	Transcriptional regulator
FD724_RS37290	COG4243	Vitamin k epoxide reductase
FD724_RS37350	COG3264	Mechanosensitive ion channel
FD724_RS37350	COG1196	nuclear chromosome segregation
FD724_RS37360	COG0745	RESPONSE REGULATOR receiver
FD724_RS37370	COG2249	NAD(P)H dehydrogenase (quinone) activity
FD724_RS37425	COG4585	Histidine kinase
FD724_RS37435	COG1215	transferase activity, transferring glycosyl groups
FD724_RS37445	COG0529	Catalyzes the synthesis of activated sulfate
FD724_RS37450	COG1028	Short-chain dehydrogenase reductase Sdr
FD724_RS37470	COG1372	Participates in initiation and elongation during chromosome replication
FD724_RS37470	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS37470	COG1372	Participates in initiation and elongation during chromosome replication
FD724_RS37470	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS37615	COG2319	Wd-40 repeat
FD724_RS37615	COG1672	PFAM Archaeal ATPase
FD724_RS37795	COG1475	DNA binding
FD724_RS38095	COG4106	trans-aconitate 2-methyltransferase activity
FD724_RS38175	COG0514	ATP-dependent DNA helicase (RecQ)
FD724_RS38360	COG5002	protein histidine kinase activity
FD724_RS38360	COG5001	Diguanylate cyclase
FD724_RS38475	COG3344	reverse transcriptase
FD724_RS38480	COG2988	succinylglutamate desuccinylase activity
FD724_RS38560	COG0582	viral genome integration into host DNA
FD724_RS38565	COG2319	Wd-40 repeat
FD724_RS38565	COG3903	Transcriptional regulator
FD724_RS38575	COG2850	peptidyl-arginine hydroxylation
FD724_RS38775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD724_RS38800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD724_RS38960	COG2319	Wd-40 repeat
FD724_RS38960	COG4249	Peptidase C14 caspase catalytic subunit p20
FD724_RS39035	COG0546	phosphoglycolate phosphatase activity
FD724_RS39055	COG3903	Transcriptional regulator
FD724_RS39055	COG2319	Wd-40 repeat
FD724_RS39275	COG1475	DNA binding
FD724_RS39280	COG1192	Involved in chromosome partitioning
FD724_RS39285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FD724_RS39305	COG3173	Aminoglycoside phosphotransferase
FD724_RS39325	COG1061	Type III restriction enzyme res subunit
FD724_RS39330	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FD724_RS39340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FD724_RS39355	COG0784	Response regulator, receiver
FD724_RS39355	COG2205	protein histidine kinase activity
FD724_RS39355	COG5002	protein histidine kinase activity
FD724_RS39440	COG3903	Transcriptional regulator
FD724_RS39440	COG3629	intracellular signal transduction
FD724_RS39505	COG0736	holo-[acyl-carrier-protein] synthase activity
FD724_RS39550	COG3795	YCII-related domain
FD724_RS39570	COG0625	glutathione transferase activity
FD724_RS39610	COG1819	glycosyl
FD724_RS39715	COG1674	ftsk spoiiie
FD724_RS39745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FD724_RS39815	COG0582	viral genome integration into host DNA
FD724_RS39885	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS39885	COG1372	Participates in initiation and elongation during chromosome replication
FD724_RS39885	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS39885	COG1372	Participates in initiation and elongation during chromosome replication
FD724_RS39895	COG4249	Peptidase C14 caspase catalytic subunit p20
FD724_RS39895	COG4249	Peptidase C14 caspase catalytic subunit p20
FD724_RS39895	COG2319	Wd-40 repeat
FD724_RS39895	COG2319	Wd-40 repeat
FD724_RS39935	COG2124	cytochrome p450
FD724_RS40050	COG1192	Involved in chromosome partitioning
FD724_RS40070	COG4974	Belongs to the 'phage' integrase family
FD724_RS40095	COG0305	Participates in initiation and elongation during chromosome replication
FD724_RS40105	COG2304	oxidoreductase activity
FD724_RS40160	COG5002	protein histidine kinase activity
FD724_RS40170	COG0582	viral genome integration into host DNA
FD724_RS40175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity