locus-tag	class	description
NOS7524_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NOS7524_RS00015	COG0592	DNA-directed DNA polymerase activity
NOS7524_RS00020	COG2203	Gaf domain
NOS7524_RS00020	COG3706	GGDEF domain
NOS7524_RS00020	COG4251	negative regulation of phosphorylation
NOS7524_RS00020	COG5001	Diguanylate cyclase
NOS7524_RS00025	COG0003	Pfam Anion-transporting ATPase
NOS7524_RS00050	COG3118	belongs to the thioredoxin family
NOS7524_RS00055	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS00065	COG0459	protein refolding
NOS7524_RS00070	COG5398	heme oxygenase
NOS7524_RS00075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NOS7524_RS00090	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS00095	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS00115	COG2304	oxidoreductase activity
NOS7524_RS00120	COG0450	alkyl hydroperoxide reductase
NOS7524_RS00135	COG0484	heat shock protein binding
NOS7524_RS00140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NOS7524_RS00170	COG3411	Ferredoxin
NOS7524_RS00190	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NOS7524_RS00195	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NOS7524_RS00235	COG0330	HflC and HflK could
NOS7524_RS00240	COG0735	belongs to the Fur family
NOS7524_RS00245	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NOS7524_RS00250	COG0047	phosphoribosylformylglycinamidine synthase activity
NOS7524_RS00265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NOS7524_RS00275	COG5002	protein histidine kinase activity
NOS7524_RS00305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NOS7524_RS00315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOS7524_RS00320	COG1120	ATPase activity
NOS7524_RS00330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NOS7524_RS00335	COG0083	homoserine kinase activity
NOS7524_RS00345	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS00370	COG2255	four-way junction helicase activity
NOS7524_RS00375	COG0107	imidazoleglycerol-phosphate synthase activity
NOS7524_RS00385	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NOS7524_RS00385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NOS7524_RS00410	COG1505	serine-type exopeptidase activity
NOS7524_RS00415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NOS7524_RS00420	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS00435	COG0612	Peptidase, M16
NOS7524_RS00445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NOS7524_RS00515	COG0542	response to heat
NOS7524_RS00520	COG0456	acetyltransferase
NOS7524_RS00525	COG0019	diaminopimelate decarboxylase activity
NOS7524_RS00530	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NOS7524_RS00535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NOS7524_RS00545	COG0484	heat shock protein binding
NOS7524_RS00565	COG1408	metallophosphoesterase
NOS7524_RS00570	COG1408	metallophosphoesterase
NOS7524_RS00575	COG2267	carboxylic ester hydrolase activity
NOS7524_RS00650	COG0071	Belongs to the small heat shock protein (HSP20) family
NOS7524_RS00675	COG1192	Involved in chromosome partitioning
NOS7524_RS00715	COG4974	Belongs to the 'phage' integrase family
NOS7524_RS00790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NOS7524_RS00795	COG0193	aminoacyl-tRNA hydrolase activity
NOS7524_RS00800	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NOS7524_RS00845	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS00860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NOS7524_RS00870	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NOS7524_RS00875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NOS7524_RS00880	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NOS7524_RS00885	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NOS7524_RS00895	COG0667	Aldo Keto reductase
NOS7524_RS00905	COG0811	peptide transport
NOS7524_RS00910	COG0848	biopolymer transport protein
NOS7524_RS00935	COG0408	coproporphyrinogen oxidase activity
NOS7524_RS00945	COG0489	protein tyrosine kinase activity
NOS7524_RS00950	COG0772	Belongs to the SEDS family
NOS7524_RS00965	COG0475	glutathione-regulated potassium exporter activity
NOS7524_RS00965	COG0589	response to stress
NOS7524_RS00970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NOS7524_RS00975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NOS7524_RS00985	COG1546	Belongs to the CinA family
NOS7524_RS00985	COG1058	Belongs to the CinA family
NOS7524_RS00990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NOS7524_RS00995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NOS7524_RS01010	COG0179	Fumarylacetoacetate (FAA) hydrolase
NOS7524_RS01015	COG0360	Binds together with S18 to 16S ribosomal RNA
NOS7524_RS01030	COG0586	Pfam SNARE associated Golgi protein
NOS7524_RS01035	COG0137	argininosuccinate synthase activity
NOS7524_RS01055	COG1216	Glycosyl transferase, family 2
NOS7524_RS01070	COG0052	Belongs to the universal ribosomal protein uS2 family
NOS7524_RS01075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NOS7524_RS01085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NOS7524_RS01090	COG1192	Involved in chromosome partitioning
NOS7524_RS01100	COG1196	nuclear chromosome segregation
NOS7524_RS01100	COG1674	ftsk spoiiie
NOS7524_RS01120	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS01125	COG0730	response to heat
NOS7524_RS01130	COG1376	ErfK ybiS ycfS ynhG family protein
NOS7524_RS01145	COG0352	thiamine-phosphate diphosphorylase activity
NOS7524_RS01175	COG4651	solute:proton antiporter activity
NOS7524_RS01175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NOS7524_RS01185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NOS7524_RS01195	COG4251	negative regulation of phosphorylation
NOS7524_RS01195	COG5001	Diguanylate cyclase
NOS7524_RS01195	COG2203	Gaf domain
NOS7524_RS01195	COG3706	GGDEF domain
NOS7524_RS01210	COG0784	Response regulator, receiver
NOS7524_RS01210	COG2205	protein histidine kinase activity
NOS7524_RS01240	COG0156	8-amino-7-oxononanoate synthase activity
NOS7524_RS01245	COG0632	four-way junction helicase activity
NOS7524_RS01260	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS01270	COG1722	exodeoxyribonuclease VII activity
NOS7524_RS01275	COG1570	exodeoxyribonuclease VII activity
NOS7524_RS01280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NOS7524_RS01320	COG0430	RNA-3'-phosphate cyclase activity
NOS7524_RS01340	COG1136	(ABC) transporter
NOS7524_RS01375	COG2070	2-Nitropropane dioxygenase
NOS7524_RS01375	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NOS7524_RS01385	COG3320	Male sterility
NOS7524_RS01385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NOS7524_RS01400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NOS7524_RS01410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NOS7524_RS01420	COG1181	Belongs to the D-alanine--D-alanine ligase family
NOS7524_RS01440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NOS7524_RS01450	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
NOS7524_RS01470	COG0297	glycogen (starch) synthase activity
NOS7524_RS01495	COG0850	regulation of cytokinetic process
NOS7524_RS01500	COG2894	cell division
NOS7524_RS01505	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NOS7524_RS01515	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NOS7524_RS01530	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS01600	COG2202	Pas domain
NOS7524_RS01600	COG2205	protein histidine kinase activity
NOS7524_RS01615	COG0735	belongs to the Fur family
NOS7524_RS01620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOS7524_RS01625	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NOS7524_RS01630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NOS7524_RS01635	COG1132	(ABC) transporter
NOS7524_RS01670	COG0489	protein tyrosine kinase activity
NOS7524_RS01675	COG2382	esterase
NOS7524_RS01675	COG3693	PFAM glycoside hydrolase, family 10
NOS7524_RS01675	COG3507	Belongs to the glycosyl hydrolase 43 family
NOS7524_RS01680	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NOS7524_RS01690	COG1215	transferase activity, transferring glycosyl groups
NOS7524_RS01710	COG1216	Glycosyl transferase, family 2
NOS7524_RS01710	COG0463	Glycosyl transferase, family 2
NOS7524_RS01715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NOS7524_RS01725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS01730	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NOS7524_RS01735	COG0484	heat shock protein binding
NOS7524_RS01740	COG0483	inositol monophosphate 1-phosphatase activity
NOS7524_RS01750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NOS7524_RS01760	COG4242	Belongs to the peptidase S51 family
NOS7524_RS01775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NOS7524_RS01790	COG1254	Belongs to the acylphosphatase family
NOS7524_RS01805	COG1283	sodium-dependent phosphate transmembrane transporter activity
NOS7524_RS01815	COG0589	response to stress
NOS7524_RS01825	COG0343	queuine tRNA-ribosyltransferase activity
NOS7524_RS01835	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NOS7524_RS01840	COG3547	Transposase (IS116 IS110 IS902 family)
NOS7524_RS01870	COG1040	competence protein
NOS7524_RS01880	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NOS7524_RS01895	COG0475	glutathione-regulated potassium exporter activity
NOS7524_RS01895	COG0589	response to stress
NOS7524_RS01900	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NOS7524_RS01915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NOS7524_RS01920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NOS7524_RS01930	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NOS7524_RS01975	COG5002	protein histidine kinase activity
NOS7524_RS01980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NOS7524_RS02000	COG0814	amino acid
NOS7524_RS02005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NOS7524_RS02010	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS02020	COG5002	protein histidine kinase activity
NOS7524_RS02020	COG0784	Response regulator, receiver
NOS7524_RS02025	COG2197	response regulator
NOS7524_RS02045	COG0784	Response regulator, receiver
NOS7524_RS02050	COG4245	von Willebrand factor, type A
NOS7524_RS02065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NOS7524_RS02100	COG0489	protein tyrosine kinase activity
NOS7524_RS02110	COG1132	(ABC) transporter
NOS7524_RS02120	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS02125	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS02135	COG1215	transferase activity, transferring glycosyl groups
NOS7524_RS02140	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS02210	COG0484	heat shock protein binding
NOS7524_RS02215	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NOS7524_RS02220	COG1959	2 iron, 2 sulfur cluster binding
NOS7524_RS02225	COG3659	wide pore channel activity
NOS7524_RS02230	COG2154	pterin-4-alpha-carbinolamine dehydratase
NOS7524_RS02245	COG1122	ATPase activity
NOS7524_RS02250	COG3688	RNA-binding protein containing a PIN domain
NOS7524_RS02260	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NOS7524_RS02265	COG1716	ATPase activity
NOS7524_RS02270	COG0363	glucosamine-6-phosphate deaminase activity
NOS7524_RS02275	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NOS7524_RS02280	COG0563	adenylate kinase activity
NOS7524_RS02300	COG2131	deaminase
NOS7524_RS02325	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NOS7524_RS02345	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NOS7524_RS02350	COG5592	hemerythrin HHE cation binding domain
NOS7524_RS02365	COG3659	wide pore channel activity
NOS7524_RS02375	COG3659	wide pore channel activity
NOS7524_RS02405	COG1872	DUF167
NOS7524_RS02410	COG0625	glutathione transferase activity
NOS7524_RS02415	COG2135	peptidase activity
NOS7524_RS02420	COG0457	Tetratricopeptide repeat
NOS7524_RS02425	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NOS7524_RS02440	COG3237	CsbD-like
NOS7524_RS02450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NOS7524_RS02455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NOS7524_RS02460	COG0573	inorganic phosphate transmembrane transporter activity
NOS7524_RS02465	COG0581	inorganic phosphate transmembrane transporter activity
NOS7524_RS02470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NOS7524_RS02485	COG2072	flavoprotein involved in K transport
NOS7524_RS02500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NOS7524_RS02505	COG0724	RNA recognition motif
NOS7524_RS02520	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NOS7524_RS02535	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NOS7524_RS02570	COG1136	(ABC) transporter
NOS7524_RS02600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NOS7524_RS02600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NOS7524_RS02625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NOS7524_RS02630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NOS7524_RS02635	COG0297	glycogen (starch) synthase activity
NOS7524_RS02640	COG0784	Response regulator, receiver
NOS7524_RS02655	COG0840	transmembrane signaling receptor activity
NOS7524_RS02655	COG2203	Gaf domain
NOS7524_RS02660	COG0784	Response regulator, receiver
NOS7524_RS02660	COG2198	Histidine kinase
NOS7524_RS02660	COG0643	Histidine kinase
NOS7524_RS02685	COG0514	ATP-dependent DNA helicase (RecQ)
NOS7524_RS02700	COG1022	Amp-dependent synthetase and ligase
NOS7524_RS02720	COG0515	serine threonine protein kinase
NOS7524_RS02720	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS02725	COG0515	serine threonine protein kinase
NOS7524_RS02725	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS02745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NOS7524_RS02765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NOS7524_RS02810	COG0443	Heat shock 70 kDa protein
NOS7524_RS02820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NOS7524_RS02825	COG0387	Pfam Sodium calcium exchanger
NOS7524_RS02840	COG2205	protein histidine kinase activity
NOS7524_RS02850	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NOS7524_RS02855	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NOS7524_RS02865	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NOS7524_RS02890	COG2373	Large extracellular alpha-helical protein
NOS7524_RS02895	COG4953	penicillin-binding protein 1C
NOS7524_RS02905	COG0435	Glutathione S-transferase
NOS7524_RS02955	COG1104	cysteine desulfurase activity
NOS7524_RS02960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NOS7524_RS02980	COG1252	NADH dehydrogenase
NOS7524_RS02990	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NOS7524_RS02995	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS03000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NOS7524_RS03015	COG0667	Aldo Keto reductase
NOS7524_RS03030	COG0405	Gamma-glutamyltransferase
NOS7524_RS03045	COG1136	(ABC) transporter
NOS7524_RS03080	COG1125	glycine betaine transport
NOS7524_RS03080	COG0517	IMP dehydrogenase activity
NOS7524_RS03100	COG0668	transmembrane transport
NOS7524_RS03105	COG0668	transmembrane transport
NOS7524_RS03110	COG0473	3-isopropylmalate dehydrogenase activity
NOS7524_RS03120	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NOS7524_RS03125	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NOS7524_RS03150	COG1785	Belongs to the alkaline phosphatase family
NOS7524_RS03165	COG1175	transmembrane transport
NOS7524_RS03200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NOS7524_RS03205	COG0275	rRNA processing
NOS7524_RS03215	COG0649	NAD binding
NOS7524_RS03220	COG2203	Gaf domain
NOS7524_RS03230	COG0318	PFAM AMP-dependent synthetase and ligase
NOS7524_RS03235	COG4948	Mandelate Racemase Muconate Lactonizing
NOS7524_RS03240	COG1575	Belongs to the MenA family. Type 1 subfamily
NOS7524_RS03250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NOS7524_RS03255	COG1797	cobyrinic acid a,c-diamide synthase activity
NOS7524_RS03260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NOS7524_RS03265	COG0151	Belongs to the GarS family
NOS7524_RS03270	COG5002	protein histidine kinase activity
NOS7524_RS03275	COG0606	chelatase, subunit chli
NOS7524_RS03280	COG0537	adenosine 5'-monophosphoramidase activity
NOS7524_RS03315	COG0367	asparagine synthase
NOS7524_RS03345	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NOS7524_RS03355	COG2046	Belongs to the sulfate adenylyltransferase family
NOS7524_RS03360	COG0482	sulfurtransferase activity
NOS7524_RS03375	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
NOS7524_RS03390	COG2319	Wd-40 repeat
NOS7524_RS03390	COG3903	Transcriptional regulator
NOS7524_RS03525	COG2188	Transcriptional regulator
NOS7524_RS03530	COG3624	Phosphonate C-P lyase system protein PhnG
NOS7524_RS03545	COG3626	phosphonate metabolism
NOS7524_RS03555	COG3454	Phosphonate metabolism
NOS7524_RS03565	COG3627	carbon phosphorus lyase activity
NOS7524_RS03570	COG4107	phosphonate C-P lyase system protein PhnK
NOS7524_RS03575	COG4778	phosphonate C-P lyase system protein PhnL
NOS7524_RS03580	COG3454	Phosphonate metabolism
NOS7524_RS03585	COG3706	GGDEF domain
NOS7524_RS03625	COG0406	alpha-ribazole phosphatase activity
NOS7524_RS03635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NOS7524_RS03660	COG0247	lactate metabolic process
NOS7524_RS03665	COG0277	FAD linked oxidase domain protein
NOS7524_RS03675	COG0306	phosphate transporter
NOS7524_RS03680	COG2226	methyltransferase
NOS7524_RS03685	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS03695	COG2226	methyltransferase
NOS7524_RS03720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NOS7524_RS03725	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS03790	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NOS7524_RS03795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NOS7524_RS03800	COG3903	Transcriptional regulator
NOS7524_RS03800	COG2319	Wd-40 repeat
NOS7524_RS03815	COG0163	prenyltransferase activity
NOS7524_RS03820	COG0557	exoribonuclease II activity
NOS7524_RS03830	COG0740	serine-type endopeptidase activity
NOS7524_RS03840	COG1331	Highly conserved protein containing a thioredoxin domain
NOS7524_RS03850	COG0746	molybdenum cofactor guanylyltransferase activity
NOS7524_RS03855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NOS7524_RS03875	COG0672	)-iron permease
NOS7524_RS03885	COG0310	cobalt ion transport
NOS7524_RS03890	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NOS7524_RS03900	COG1122	ATPase activity
NOS7524_RS03905	COG0310	cobalt ion transport
NOS7524_RS03915	COG1122	ATPase activity
NOS7524_RS03920	COG0561	phosphatase activity
NOS7524_RS03930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NOS7524_RS03935	COG0583	DNA-binding transcription factor activity
NOS7524_RS03945	COG3118	belongs to the thioredoxin family
NOS7524_RS03955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NOS7524_RS03975	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS04000	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NOS7524_RS04005	COG3668	Plasmid stabilization system
NOS7524_RS04030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NOS7524_RS04040	COG2815	serine threonine protein kinase
NOS7524_RS04040	COG0515	serine threonine protein kinase
NOS7524_RS04055	COG2226	methyltransferase
NOS7524_RS04065	COG1846	Transcriptional regulator
NOS7524_RS04085	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS04090	COG5002	protein histidine kinase activity
NOS7524_RS04095	COG0704	Plays a role in the regulation of phosphate uptake
NOS7524_RS04100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NOS7524_RS04105	COG3659	wide pore channel activity
NOS7524_RS04140	COG0463	Glycosyl transferase, family 2
NOS7524_RS04155	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NOS7524_RS04180	COG4294	response to UV
NOS7524_RS04185	COG0443	Heat shock 70 kDa protein
NOS7524_RS04205	COG0515	serine threonine protein kinase
NOS7524_RS04205	COG3266	domain, Protein
NOS7524_RS04210	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NOS7524_RS04235	COG1131	(ABC) transporter
NOS7524_RS04240	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NOS7524_RS04250	COG1316	TRANSCRIPTIONal
NOS7524_RS04255	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS04260	COG0728	peptidoglycan biosynthetic process
NOS7524_RS04275	COG2132	Multicopper oxidase
NOS7524_RS04290	COG0716	FMN binding
NOS7524_RS04320	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS04325	COG5002	protein histidine kinase activity
NOS7524_RS04335	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NOS7524_RS04365	COG1136	(ABC) transporter
NOS7524_RS04365	COG0577	efflux transmembrane transporter activity
NOS7524_RS04375	COG2205	protein histidine kinase activity
NOS7524_RS04375	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS04375	COG3292	Two component regulator propeller
NOS7524_RS04420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NOS7524_RS04425	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NOS7524_RS04455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NOS7524_RS04475	COG0406	alpha-ribazole phosphatase activity
NOS7524_RS04480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NOS7524_RS04490	COG1518	maintenance of DNA repeat elements
NOS7524_RS04535	COG4804	nuclease activity
NOS7524_RS04565	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS04570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NOS7524_RS04575	COG0509	glycine decarboxylation via glycine cleavage system
NOS7524_RS04580	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NOS7524_RS04580	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NOS7524_RS04630	COG0024	Methionine aminopeptidase
NOS7524_RS04645	COG2385	sporulation resulting in formation of a cellular spore
NOS7524_RS04655	COG0783	Belongs to the Dps family
NOS7524_RS04670	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS04685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NOS7524_RS04690	COG2205	protein histidine kinase activity
NOS7524_RS04690	COG0784	Response regulator, receiver
NOS7524_RS04695	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NOS7524_RS04705	COG0830	nickel cation binding
NOS7524_RS04710	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NOS7524_RS04720	COG0731	radical SAM domain protein
NOS7524_RS04725	COG4191	Histidine kinase
NOS7524_RS04725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NOS7524_RS04730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NOS7524_RS04735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NOS7524_RS04800	COG0517	IMP dehydrogenase activity
NOS7524_RS04800	COG1994	Peptidase M50
NOS7524_RS04805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NOS7524_RS04815	COG0726	polysaccharide deacetylase
NOS7524_RS04825	COG2205	protein histidine kinase activity
NOS7524_RS04850	COG1482	cell wall glycoprotein biosynthetic process
NOS7524_RS04860	COG2205	protein histidine kinase activity
NOS7524_RS04860	COG0784	Response regulator, receiver
NOS7524_RS04865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NOS7524_RS04870	COG0572	uridine kinase
NOS7524_RS04875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NOS7524_RS04880	COG0460	homoserine dehydrogenase
NOS7524_RS04885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NOS7524_RS04895	COG0596	Alpha beta hydrolase
NOS7524_RS04935	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NOS7524_RS04940	COG3959	Transketolase, thiamine diphosphate binding domain
NOS7524_RS04950	COG0613	PHP domain protein
NOS7524_RS04955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NOS7524_RS04965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NOS7524_RS04970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NOS7524_RS04970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NOS7524_RS04975	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NOS7524_RS04980	COG2066	Belongs to the glutaminase family
NOS7524_RS04985	COG1649	PFAM Uncharacterised BCR, COG1649
NOS7524_RS05045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NOS7524_RS05050	COG1234	tRNA 3'-trailer cleavage
NOS7524_RS05125	COG0110	maltose O-acetyltransferase activity
NOS7524_RS05135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NOS7524_RS05140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NOS7524_RS05145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NOS7524_RS05155	COG1116	anion transmembrane transporter activity
NOS7524_RS05160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NOS7524_RS05160	COG1116	anion transmembrane transporter activity
NOS7524_RS05165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NOS7524_RS05180	COG0571	ribonuclease III activity
NOS7524_RS05195	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
NOS7524_RS05195	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
NOS7524_RS05210	COG0670	Belongs to the BI1 family
NOS7524_RS05215	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NOS7524_RS05220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NOS7524_RS05225	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NOS7524_RS05230	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NOS7524_RS05230	COG0512	Glutamine amidotransferase of anthranilate synthase
NOS7524_RS05245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NOS7524_RS05265	COG0589	response to stress
NOS7524_RS05265	COG0475	glutathione-regulated potassium exporter activity
NOS7524_RS05270	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NOS7524_RS05275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NOS7524_RS05280	COG0004	ammonium transporteR
NOS7524_RS05285	COG0004	ammonium transporteR
NOS7524_RS05310	COG0004	ammonium transporteR
NOS7524_RS05320	COG0492	ferredoxin-NADP+ reductase activity
NOS7524_RS05325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NOS7524_RS05330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NOS7524_RS05335	COG0321	lipoyl(octanoyl) transferase activity
NOS7524_RS05340	COG0765	amino acid transport
NOS7524_RS05355	COG0640	Transcriptional regulator
NOS7524_RS05375	COG0723	plastoquinol--plastocyanin reductase activity
NOS7524_RS05380	COG0446	pyridine nucleotide-disulphide oxidoreductase
NOS7524_RS05395	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NOS7524_RS05405	COG1850	ribulose-bisphosphate carboxylase activity
NOS7524_RS05415	COG4451	ribulose bisphosphate carboxylase, small
NOS7524_RS05475	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NOS7524_RS05480	COG1333	cytochrome c biogenesis protein
NOS7524_RS05485	COG4232	protein-disulfide reductase activity
NOS7524_RS05490	COG3920	Histidine kinase
NOS7524_RS05495	COG5002	protein histidine kinase activity
NOS7524_RS05520	COG1649	PFAM Uncharacterised BCR, COG1649
NOS7524_RS05530	COG0564	pseudouridine synthase activity
NOS7524_RS05545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NOS7524_RS05555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NOS7524_RS05570	COG3956	TIGRFAM MazG family protein
NOS7524_RS05585	COG2267	carboxylic ester hydrolase activity
NOS7524_RS05595	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NOS7524_RS05600	COG0375	protein maturation
NOS7524_RS05615	COG0409	Hydrogenase expression formation protein
NOS7524_RS05620	COG0298	carbon dioxide binding
NOS7524_RS05650	COG1252	NADH dehydrogenase
NOS7524_RS05700	COG1487	ribonuclease activity
NOS7524_RS05755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NOS7524_RS05760	COG0316	Belongs to the HesB IscA family
NOS7524_RS05765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NOS7524_RS05775	COG5420	small protein containing a coiled-coil domain
NOS7524_RS05790	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
NOS7524_RS05795	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
NOS7524_RS05830	COG0582	viral genome integration into host DNA
NOS7524_RS05835	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
NOS7524_RS05840	COG0582	viral genome integration into host DNA
NOS7524_RS05855	COG1943	Transposase
NOS7524_RS05880	COG1442	glycosyl transferase family 8
NOS7524_RS05895	COG0827	DNA restriction-modification system
NOS7524_RS05900	COG0827	DNA restriction-modification system
NOS7524_RS05920	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
NOS7524_RS05925	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
NOS7524_RS05930	COG0582	viral genome integration into host DNA
NOS7524_RS05965	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NOS7524_RS05970	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
NOS7524_RS05975	COG2906	2 iron, 2 sulfur cluster binding
NOS7524_RS05975	COG0822	iron-sulfur transferase activity
NOS7524_RS05975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NOS7524_RS06040	COG0515	serine threonine protein kinase
NOS7524_RS06040	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS06055	COG0463	Glycosyl transferase, family 2
NOS7524_RS06065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NOS7524_RS06070	COG0523	cobalamin synthesis protein
NOS7524_RS06075	COG0302	gtp cyclohydrolase
NOS7524_RS06210	COG2239	Acts as a magnesium transporter
NOS7524_RS06215	COG0540	Belongs to the ATCase OTCase family
NOS7524_RS06225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NOS7524_RS06245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NOS7524_RS06255	COG4636	protein conserved in cyanobacteria
NOS7524_RS06275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NOS7524_RS06280	COG0742	ribosomal rna small subunit methyltransferase
NOS7524_RS06290	COG2010	Cytochrome c
NOS7524_RS06305	COG1420	regulation of RNA biosynthetic process
NOS7524_RS06330	COG1045	serine acetyltransferase
NOS7524_RS06335	COG0259	pyridoxamine-phosphate oxidase activity
NOS7524_RS06340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NOS7524_RS06350	COG0724	RNA recognition motif
NOS7524_RS06355	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NOS7524_RS06360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NOS7524_RS06365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NOS7524_RS06370	COG3429	Glucose-6-phosphate dehydrogenase subunit
NOS7524_RS06370	COG3409	Peptidoglycan-binding domain 1 protein
NOS7524_RS06375	COG1012	belongs to the aldehyde dehydrogenase family
NOS7524_RS06385	COG2815	serine threonine protein kinase
NOS7524_RS06385	COG0515	serine threonine protein kinase
NOS7524_RS06390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NOS7524_RS06435	COG0481	GTPase activity
NOS7524_RS06445	COG3437	response regulator, receiver
NOS7524_RS06445	COG2205	protein histidine kinase activity
NOS7524_RS06445	COG3850	Histidine kinase
NOS7524_RS06445	COG4999	Histidine kinase
NOS7524_RS06455	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NOS7524_RS06465	COG1690	Belongs to the RtcB family
NOS7524_RS06470	COG2226	methyltransferase
NOS7524_RS06475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NOS7524_RS06495	COG0612	Peptidase, M16
NOS7524_RS06500	COG0612	Peptidase, M16
NOS7524_RS06515	COG0318	PFAM AMP-dependent synthetase and ligase
NOS7524_RS06520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NOS7524_RS06560	COG3321	synthase
NOS7524_RS06560	COG0604	alcohol dehydrogenase
NOS7524_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS06565	COG0560	Phosphoserine phosphatase
NOS7524_RS06575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NOS7524_RS06575	COG2070	2-Nitropropane dioxygenase
NOS7524_RS06630	COG0720	synthase
NOS7524_RS06640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NOS7524_RS06640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NOS7524_RS06655	COG1077	Cell shape determining protein MreB Mrl
NOS7524_RS06660	COG0629	single-stranded DNA binding
NOS7524_RS06670	COG0475	glutathione-regulated potassium exporter activity
NOS7524_RS06680	COG0860	N-Acetylmuramoyl-L-alanine amidase
NOS7524_RS06685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NOS7524_RS06695	COG0142	geranyltranstransferase activity
NOS7524_RS06720	COG2052	Domain of unknown function (DUF370)
NOS7524_RS06725	COG0194	GDP metabolic process
NOS7524_RS06745	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NOS7524_RS06750	COG2267	carboxylic ester hydrolase activity
NOS7524_RS06760	COG0454	-acetyltransferase
NOS7524_RS06775	COG2890	protein-(glutamine-N5) methyltransferase activity
NOS7524_RS06790	COG0456	acetyltransferase
NOS7524_RS06800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NOS7524_RS06805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NOS7524_RS06810	COG0022	dehydrogenase e1 component
NOS7524_RS06810	COG0508	dehydrogenase complex catalyzes the overall conversion of
NOS7524_RS06825	COG0113	porphobilinogen synthase activity
NOS7524_RS06830	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NOS7524_RS06835	COG0501	Belongs to the peptidase M48B family
NOS7524_RS06845	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS06850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NOS7524_RS06860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NOS7524_RS06885	COG2045	Belongs to the ComB family
NOS7524_RS06900	COG0124	histidyl-tRNA synthetase
NOS7524_RS06905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NOS7524_RS06910	COG0542	response to heat
NOS7524_RS06925	COG1127	ABC transporter
NOS7524_RS06930	COG1233	COG1233 Phytoene dehydrogenase and related
NOS7524_RS06945	COG0134	indole-3-glycerol-phosphate synthase activity
NOS7524_RS06955	COG0512	Glutamine amidotransferase of anthranilate synthase
NOS7524_RS06955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NOS7524_RS06960	COG3437	response regulator, receiver
NOS7524_RS06970	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NOS7524_RS06975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NOS7524_RS06980	COG3093	addiction module antidote protein HigA
NOS7524_RS06995	COG3266	domain, Protein
NOS7524_RS06995	COG0515	serine threonine protein kinase
NOS7524_RS07015	COG0582	viral genome integration into host DNA
NOS7524_RS07040	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NOS7524_RS07055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NOS7524_RS07065	COG0432	Pfam Uncharacterised protein family UPF0047
NOS7524_RS07075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NOS7524_RS07110	COG3335	DDE superfamily endonuclease
NOS7524_RS07115	COG0515	serine threonine protein kinase
NOS7524_RS07120	COG0515	serine threonine protein kinase
NOS7524_RS07130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NOS7524_RS07140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NOS7524_RS07150	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NOS7524_RS07155	COG0006	proline dipeptidase activity
NOS7524_RS07170	COG2363	Small membrane protein
NOS7524_RS07175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NOS7524_RS07180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NOS7524_RS07205	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NOS7524_RS07210	COG0519	Catalyzes the synthesis of GMP from XMP
NOS7524_RS07210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NOS7524_RS07225	COG0784	Response regulator, receiver
NOS7524_RS07230	COG4251	negative regulation of phosphorylation
NOS7524_RS07235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NOS7524_RS07245	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NOS7524_RS07270	COG0009	L-threonylcarbamoyladenylate synthase
NOS7524_RS07275	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NOS7524_RS07315	COG0159	tryptophan synthase activity
NOS7524_RS07325	COG0515	serine threonine protein kinase
NOS7524_RS07325	COG3266	domain, Protein
NOS7524_RS07340	COG2234	aminopeptidase activity
NOS7524_RS07370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NOS7524_RS07380	COG1132	(ABC) transporter
NOS7524_RS07385	COG3852	Histidine kinase
NOS7524_RS07395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NOS7524_RS07405	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NOS7524_RS07450	COG2205	protein histidine kinase activity
NOS7524_RS07465	COG0571	ribonuclease III activity
NOS7524_RS07475	COG0598	Magnesium transport protein CorA
NOS7524_RS07515	COG0215	cysteine-tRNA ligase activity
NOS7524_RS07520	COG0523	cobalamin synthesis protein
NOS7524_RS07530	COG0521	Mo-molybdopterin cofactor biosynthetic process
NOS7524_RS07535	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NOS7524_RS07560	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NOS7524_RS07560	COG1404	Belongs to the peptidase S8 family
NOS7524_RS07575	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NOS7524_RS07580	COG0653	protein targeting
NOS7524_RS07600	COG0714	Associated with various cellular activities
NOS7524_RS07605	COG0196	riboflavin kinase activity
NOS7524_RS07610	COG1234	tRNA 3'-trailer cleavage
NOS7524_RS07615	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NOS7524_RS07620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NOS7524_RS07650	COG0514	ATP-dependent DNA helicase (RecQ)
NOS7524_RS07655	COG1598	PFAM Uncharacterised protein family UPF0150
NOS7524_RS07660	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NOS7524_RS07670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NOS7524_RS07680	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS07680	COG0515	serine threonine protein kinase
NOS7524_RS07695	COG0829	nickel cation binding
NOS7524_RS07700	COG0831	urea catabolic process
NOS7524_RS07705	COG0832	Belongs to the urease beta subunit family
NOS7524_RS07715	COG0804	urea catabolic process
NOS7524_RS07725	COG1012	belongs to the aldehyde dehydrogenase family
NOS7524_RS07730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NOS7524_RS07735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NOS7524_RS07755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NOS7524_RS07760	COG0346	lactoylglutathione lyase activity
NOS7524_RS07765	COG0798	PFAM Bile acid sodium symporter
NOS7524_RS07775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NOS7524_RS07780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NOS7524_RS07785	COG0640	Transcriptional regulator
NOS7524_RS07795	COG0436	Aminotransferase
NOS7524_RS07800	COG0371	Dehydrogenase
NOS7524_RS07820	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS07820	COG0515	serine threonine protein kinase
NOS7524_RS07825	COG0515	serine threonine protein kinase
NOS7524_RS07825	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS07890	COG1940	carbohydrate kinase activity
NOS7524_RS07900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NOS7524_RS07905	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NOS7524_RS07910	COG0436	Aminotransferase
NOS7524_RS07915	COG3118	belongs to the thioredoxin family
NOS7524_RS07930	COG1309	transcriptional regulator
NOS7524_RS07940	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NOS7524_RS07950	COG0739	heme binding
NOS7524_RS08015	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NOS7524_RS08035	COG2197	response regulator
NOS7524_RS08040	COG3851	Histidine kinase
NOS7524_RS08050	COG0784	Response regulator, receiver
NOS7524_RS08050	COG5002	protein histidine kinase activity
NOS7524_RS08080	COG2723	6-phospho-beta-galactosidase activity
NOS7524_RS08085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NOS7524_RS08095	COG2124	cytochrome p450
NOS7524_RS08100	COG1858	cytochrome C peroxidase
NOS7524_RS08125	COG0300	oxidoreductase activity
NOS7524_RS08135	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NOS7524_RS08150	COG1598	PFAM Uncharacterised protein family UPF0150
NOS7524_RS08155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NOS7524_RS08175	COG3845	ABC transporter
NOS7524_RS08180	COG1172	Belongs to the binding-protein-dependent transport system permease family
NOS7524_RS08185	COG1079	Belongs to the binding-protein-dependent transport system permease family
NOS7524_RS08190	COG0515	serine threonine protein kinase
NOS7524_RS08190	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS08205	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NOS7524_RS08215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NOS7524_RS08235	COG0730	response to heat
NOS7524_RS08240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NOS7524_RS08245	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NOS7524_RS08250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NOS7524_RS08255	COG4208	sulfate ABC transporter
NOS7524_RS08260	COG0671	phosphoesterase, PA-phosphatase related
NOS7524_RS08270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NOS7524_RS08275	COG0589	response to stress
NOS7524_RS08290	COG2319	Wd-40 repeat
NOS7524_RS08290	COG1672	PFAM Archaeal ATPase
NOS7524_RS08305	COG3903	Transcriptional regulator
NOS7524_RS08305	COG2319	Wd-40 repeat
NOS7524_RS08325	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS08335	COG0589	response to stress
NOS7524_RS08360	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS08375	COG3259	Nickel-dependent hydrogenase
NOS7524_RS08395	COG1132	(ABC) transporter
NOS7524_RS08400	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS08415	COG5002	protein histidine kinase activity
NOS7524_RS08420	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS08430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NOS7524_RS08435	COG3536	Protein conserved in bacteria
NOS7524_RS08470	COG0752	glycyl-tRNA synthetase alpha subunit
NOS7524_RS08490	COG0110	maltose O-acetyltransferase activity
NOS7524_RS08510	COG0574	Belongs to the PEP-utilizing enzyme family
NOS7524_RS08510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NOS7524_RS08515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NOS7524_RS08540	COG4948	Mandelate Racemase Muconate Lactonizing
NOS7524_RS08555	COG0678	peroxiredoxin activity
NOS7524_RS08565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NOS7524_RS08570	COG4783	chaperone-mediated protein folding
NOS7524_RS08600	COG2274	protein secretion by the type I secretion system
NOS7524_RS08645	COG0523	cobalamin synthesis protein
NOS7524_RS08660	COG2166	iron-sulfur cluster assembly
NOS7524_RS08685	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NOS7524_RS08695	COG2082	Precorrin-8x methylmutase
NOS7524_RS08740	COG1473	amidohydrolase
NOS7524_RS08750	COG0784	Response regulator, receiver
NOS7524_RS08755	COG0322	excinuclease ABC activity
NOS7524_RS08765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NOS7524_RS08785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NOS7524_RS08810	COG0751	glycine-tRNA ligase activity
NOS7524_RS08815	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NOS7524_RS08885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NOS7524_RS08910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NOS7524_RS08910	COG1013	pyruvate-flavodoxin oxidoreductase activity
NOS7524_RS08910	COG0674	pyruvate-flavodoxin oxidoreductase activity
NOS7524_RS08910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NOS7524_RS08915	COG0167	dihydroorotate dehydrogenase activity
NOS7524_RS08920	COG0205	6-phosphofructokinase activity
NOS7524_RS08945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NOS7524_RS08950	COG3693	PFAM glycoside hydrolase, family 10
NOS7524_RS08960	COG2326	polyphosphate kinase activity
NOS7524_RS08975	COG0574	Belongs to the PEP-utilizing enzyme family
NOS7524_RS08975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NOS7524_RS08980	COG0589	response to stress
NOS7524_RS08985	COG0469	pyruvate kinase activity
NOS7524_RS09000	COG0113	porphobilinogen synthase activity
NOS7524_RS09020	COG4636	protein conserved in cyanobacteria
NOS7524_RS09030	COG3240	lipase activity
NOS7524_RS09090	COG3848	Pyruvate phosphate dikinase
NOS7524_RS09090	COG0574	Belongs to the PEP-utilizing enzyme family
NOS7524_RS09110	COG0659	secondary active sulfate transmembrane transporter activity
NOS7524_RS09115	COG0475	glutathione-regulated potassium exporter activity
NOS7524_RS09120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NOS7524_RS09125	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NOS7524_RS09150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NOS7524_RS09180	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS09190	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS09195	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS09225	COG0110	maltose O-acetyltransferase activity
NOS7524_RS09235	COG0463	Glycosyl transferase, family 2
NOS7524_RS09275	COG2089	acid synthase
NOS7524_RS09285	COG0500	methyltransferase
NOS7524_RS09325	COG0489	protein tyrosine kinase activity
NOS7524_RS09350	COG2183	response to ionizing radiation
NOS7524_RS09365	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NOS7524_RS09380	COG1136	(ABC) transporter
NOS7524_RS09380	COG0577	efflux transmembrane transporter activity
NOS7524_RS09395	COG1695	Transcriptional regulator
NOS7524_RS09410	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS09415	COG1177	transmembrane transport
NOS7524_RS09420	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS09420	COG0515	serine threonine protein kinase
NOS7524_RS09425	COG3210	domain, Protein
NOS7524_RS09450	COG0697	spore germination
NOS7524_RS09460	COG1252	NADH dehydrogenase
NOS7524_RS09470	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS09475	COG5002	protein histidine kinase activity
NOS7524_RS09490	COG5002	protein histidine kinase activity
NOS7524_RS09510	COG2124	cytochrome p450
NOS7524_RS09525	COG0811	peptide transport
NOS7524_RS09555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NOS7524_RS09565	COG1214	PFAM Peptidase M22, glycoprotease
NOS7524_RS09575	COG2205	protein histidine kinase activity
NOS7524_RS09575	COG0784	Response regulator, receiver
NOS7524_RS09575	COG2198	Histidine kinase
NOS7524_RS09590	COG0617	tRNA 3'-terminal CCA addition
NOS7524_RS09645	COG1429	ligase activity, forming nitrogen-metal bonds
NOS7524_RS09660	COG5000	phosphorelay sensor kinase activity
NOS7524_RS09660	COG5002	protein histidine kinase activity
NOS7524_RS09690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NOS7524_RS09695	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NOS7524_RS09700	COG2080	2 iron, 2 sulfur cluster binding
NOS7524_RS09720	COG0066	3-isopropylmalate dehydratase activity
NOS7524_RS09725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NOS7524_RS09740	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS09765	COG3209	COG3209 Rhs family protein
NOS7524_RS09770	COG3547	Transposase (IS116 IS110 IS902 family)
NOS7524_RS09785	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS09810	COG0586	Pfam SNARE associated Golgi protein
NOS7524_RS09825	COG0625	glutathione transferase activity
NOS7524_RS09860	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NOS7524_RS09910	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NOS7524_RS09925	COG3920	Histidine kinase
NOS7524_RS09945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NOS7524_RS09965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NOS7524_RS10000	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS10000	COG0515	serine threonine protein kinase
NOS7524_RS10010	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NOS7524_RS10070	COG2267	carboxylic ester hydrolase activity
NOS7524_RS10085	COG1309	transcriptional regulator
NOS7524_RS10095	COG0587	DNA-directed DNA polymerase activity
NOS7524_RS10105	COG3033	Beta-eliminating lyase
NOS7524_RS10130	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NOS7524_RS10165	COG1054	Belongs to the UPF0176 family
NOS7524_RS10175	COG1832	CoA-binding protein
NOS7524_RS10180	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS10190	COG2239	Acts as a magnesium transporter
NOS7524_RS10200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NOS7524_RS10205	COG0398	Pfam SNARE associated Golgi protein
NOS7524_RS10210	COG0398	Pfam SNARE associated Golgi protein
NOS7524_RS10225	COG1316	TRANSCRIPTIONal
NOS7524_RS10235	COG0628	permease
NOS7524_RS10260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NOS7524_RS10260	COG0574	Belongs to the PEP-utilizing enzyme family
NOS7524_RS10270	COG0724	RNA recognition motif
NOS7524_RS10275	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NOS7524_RS10290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NOS7524_RS10295	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS10310	COG0463	Glycosyl transferase, family 2
NOS7524_RS10315	COG1215	transferase activity, transferring glycosyl groups
NOS7524_RS10335	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS10385	COG2119	membrane
NOS7524_RS10415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NOS7524_RS10415	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NOS7524_RS10440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NOS7524_RS10470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NOS7524_RS10485	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NOS7524_RS10505	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NOS7524_RS10505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NOS7524_RS10515	COG0242	peptide deformylase activity
NOS7524_RS10550	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NOS7524_RS10560	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NOS7524_RS10570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NOS7524_RS10575	COG0750	zinc metalloprotease
NOS7524_RS10590	COG2161	toxin-antitoxin pair type II binding
NOS7524_RS10595	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NOS7524_RS10620	COG2205	protein histidine kinase activity
NOS7524_RS10625	COG1361	Conserved repeat domain
NOS7524_RS10635	COG0419	ATPase involved in DNA repair
NOS7524_RS10640	COG0860	N-Acetylmuramoyl-L-alanine amidase
NOS7524_RS10640	COG3409	Peptidoglycan-binding domain 1 protein
NOS7524_RS10650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NOS7524_RS10665	COG0793	Belongs to the peptidase S41A family
NOS7524_RS10675	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NOS7524_RS10710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NOS7524_RS10735	COG0038	chloride channel
NOS7524_RS10745	COG1959	2 iron, 2 sulfur cluster binding
NOS7524_RS10750	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NOS7524_RS10755	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NOS7524_RS10785	COG1372	Participates in initiation and elongation during chromosome replication
NOS7524_RS10785	COG0305	Participates in initiation and elongation during chromosome replication
NOS7524_RS10790	COG0359	binds to the 23S rRNA
NOS7524_RS10795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NOS7524_RS10825	COG1132	(ABC) transporter
NOS7524_RS10855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NOS7524_RS10865	COG0308	aminopeptidase N
NOS7524_RS10880	COG4196	transglutaminase domain protein
NOS7524_RS10885	COG1131	(ABC) transporter
NOS7524_RS10905	COG0788	formyltetrahydrofolate deformylase activity
NOS7524_RS10910	COG0315	cyclic pyranopterin monophosphate synthase activity
NOS7524_RS10920	COG2814	Major facilitator Superfamily
NOS7524_RS10925	COG0463	Glycosyl transferase, family 2
NOS7524_RS10940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NOS7524_RS10950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NOS7524_RS10955	COG0596	Alpha beta hydrolase
NOS7524_RS10965	COG0702	epimerase
NOS7524_RS10980	COG0666	response to abiotic stimulus
NOS7524_RS10995	COG1950	PFAM Membrane protein of
NOS7524_RS11005	COG0612	Peptidase, M16
NOS7524_RS11010	COG0612	Peptidase, M16
NOS7524_RS11015	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NOS7524_RS11030	COG2201	protein-glutamate methylesterase activity
NOS7524_RS11045	COG0840	transmembrane signaling receptor activity
NOS7524_RS11045	COG2203	Gaf domain
NOS7524_RS11050	COG2198	Histidine kinase
NOS7524_RS11050	COG0643	Histidine kinase
NOS7524_RS11050	COG0784	Response regulator, receiver
NOS7524_RS11065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NOS7524_RS11070	COG2217	Heavy metal translocating P-type atpase
NOS7524_RS11080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NOS7524_RS11095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NOS7524_RS11110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NOS7524_RS11115	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NOS7524_RS11125	COG2010	Cytochrome c
NOS7524_RS11250	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NOS7524_RS11250	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NOS7524_RS11250	COG1013	pyruvate-flavodoxin oxidoreductase activity
NOS7524_RS11250	COG0674	pyruvate-flavodoxin oxidoreductase activity
NOS7524_RS11260	COG0071	Belongs to the small heat shock protein (HSP20) family
NOS7524_RS11265	COG2076	Multidrug Resistance protein
NOS7524_RS11270	COG4249	Peptidase C14 caspase catalytic subunit p20
NOS7524_RS11270	COG2319	Wd-40 repeat
NOS7524_RS11295	COG3903	Transcriptional regulator
NOS7524_RS11295	COG2319	Wd-40 repeat
NOS7524_RS11300	COG2119	membrane
NOS7524_RS11330	COG3266	domain, Protein
NOS7524_RS11330	COG0515	serine threonine protein kinase
NOS7524_RS11335	COG0515	serine threonine protein kinase
NOS7524_RS11345	COG2972	Histidine kinase
NOS7524_RS11345	COG2205	protein histidine kinase activity
NOS7524_RS11355	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NOS7524_RS11400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NOS7524_RS11440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NOS7524_RS11450	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NOS7524_RS11480	COG0557	exoribonuclease II activity
NOS7524_RS11485	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NOS7524_RS11495	COG0303	'Molybdopterin
NOS7524_RS11500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NOS7524_RS11510	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NOS7524_RS11525	COG2226	methyltransferase
NOS7524_RS11530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NOS7524_RS11545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NOS7524_RS11565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NOS7524_RS11565	COG1181	Belongs to the D-alanine--D-alanine ligase family
NOS7524_RS11570	COG1304	FMN binding
NOS7524_RS11575	COG0616	signal peptide processing
NOS7524_RS11600	COG4935	Belongs to the peptidase S8 family
NOS7524_RS11600	COG1404	Belongs to the peptidase S8 family
NOS7524_RS11635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NOS7524_RS11635	COG0072	phenylalanine-tRNA ligase activity
NOS7524_RS11675	COG0352	thiamine-phosphate diphosphorylase activity
NOS7524_RS11705	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NOS7524_RS11720	COG3335	DDE superfamily endonuclease
NOS7524_RS11725	COG0495	leucyl-tRNA aminoacylation
NOS7524_RS11740	COG1595	DNA-templated transcription, initiation
NOS7524_RS11760	COG1619	proteins homologs of microcin C7 resistance protein MccF
NOS7524_RS11765	COG1501	Belongs to the glycosyl hydrolase 31 family
NOS7524_RS11785	COG2010	Cytochrome c
NOS7524_RS11795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOS7524_RS11800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NOS7524_RS11805	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NOS7524_RS11820	COG1940	carbohydrate kinase activity
NOS7524_RS11850	COG0529	Catalyzes the synthesis of activated sulfate
NOS7524_RS11865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NOS7524_RS11875	COG0724	RNA recognition motif
NOS7524_RS11890	COG0725	ABC transporter, periplasmic molybdate-binding protein
NOS7524_RS11920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NOS7524_RS11930	COG3842	ATPase activity
NOS7524_RS11955	COG0629	single-stranded DNA binding
NOS7524_RS11970	COG4249	Peptidase C14 caspase catalytic subunit p20
NOS7524_RS11970	COG2319	Wd-40 repeat
NOS7524_RS12050	COG2223	nitrite transmembrane transporter activity
NOS7524_RS12060	COG0456	acetyltransferase
NOS7524_RS12070	COG0662	Cupin 2, conserved barrel domain protein
NOS7524_RS12070	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NOS7524_RS12085	COG2205	protein histidine kinase activity
NOS7524_RS12110	COG1968	undecaprenyl-diphosphatase activity
NOS7524_RS12120	COG1555	photosystem II stabilization
NOS7524_RS12125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NOS7524_RS12140	COG4243	Vitamin k epoxide reductase
NOS7524_RS12145	COG0434	BtpA family
NOS7524_RS12150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NOS7524_RS12155	COG0513	Belongs to the DEAD box helicase family
NOS7524_RS12175	COG0483	inositol monophosphate 1-phosphatase activity
NOS7524_RS12200	COG1063	alcohol dehydrogenase
NOS7524_RS12205	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NOS7524_RS12240	COG0463	Glycosyl transferase, family 2
NOS7524_RS12245	COG0463	Glycosyl transferase, family 2
NOS7524_RS12245	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NOS7524_RS12250	COG1216	Glycosyl transferase, family 2
NOS7524_RS12260	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS12280	COG0469	pyruvate kinase activity
NOS7524_RS12295	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NOS7524_RS12315	COG0616	signal peptide processing
NOS7524_RS12325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NOS7524_RS12345	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NOS7524_RS12395	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NOS7524_RS12410	COG1696	Membrane protein involved in D-alanine export
NOS7524_RS12420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NOS7524_RS12430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NOS7524_RS12460	COG0191	fructose-bisphosphate aldolase activity
NOS7524_RS12475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NOS7524_RS12525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NOS7524_RS12525	COG0758	DNA mediated transformation
NOS7524_RS12545	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NOS7524_RS12550	COG1104	cysteine desulfurase activity
NOS7524_RS12575	COG1061	Type III restriction enzyme res subunit
NOS7524_RS12590	COG0482	sulfurtransferase activity
NOS7524_RS12635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NOS7524_RS12640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NOS7524_RS12645	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NOS7524_RS12695	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS12695	COG0515	serine threonine protein kinase
NOS7524_RS12700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NOS7524_RS12710	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NOS7524_RS12710	COG0140	phosphoribosyl-ATP diphosphatase activity
NOS7524_RS12720	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS12735	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NOS7524_RS12750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NOS7524_RS12755	COG0284	orotidine-5'-phosphate decarboxylase activity
NOS7524_RS12755	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NOS7524_RS12760	COG0628	permease
NOS7524_RS12805	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS12815	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NOS7524_RS12820	COG4251	negative regulation of phosphorylation
NOS7524_RS12825	COG4251	negative regulation of phosphorylation
NOS7524_RS12865	COG3639	organic phosphonate transmembrane transporter activity
NOS7524_RS12870	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NOS7524_RS12875	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NOS7524_RS12880	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NOS7524_RS12885	COG3659	wide pore channel activity
NOS7524_RS12890	COG0668	transmembrane transport
NOS7524_RS12895	COG0668	transmembrane transport
NOS7524_RS12900	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NOS7524_RS12955	COG0668	transmembrane transport
NOS7524_RS12965	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NOS7524_RS12975	COG0121	glutamine amidotransferase
NOS7524_RS12980	COG1846	Transcriptional regulator
NOS7524_RS12985	COG1960	acyl-CoA dehydrogenase activity
NOS7524_RS13020	COG2501	S4 domain
NOS7524_RS13025	COG3546	catalase activity
NOS7524_RS13055	COG0693	protein deglycase activity
NOS7524_RS13085	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NOS7524_RS13090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NOS7524_RS13090	COG0426	domain, Protein
NOS7524_RS13100	COG0426	domain, Protein
NOS7524_RS13100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NOS7524_RS13155	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NOS7524_RS13200	COG1295	ribonuclease BN
NOS7524_RS13240	COG3903	Transcriptional regulator
NOS7524_RS13240	COG3629	intracellular signal transduction
NOS7524_RS13250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NOS7524_RS13275	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS13290	COG0515	serine threonine protein kinase
NOS7524_RS13290	COG3266	domain, Protein
NOS7524_RS13305	COG5001	Diguanylate cyclase
NOS7524_RS13305	COG3706	GGDEF domain
NOS7524_RS13305	COG2203	Gaf domain
NOS7524_RS13305	COG4251	negative regulation of phosphorylation
NOS7524_RS13315	COG1649	PFAM Uncharacterised BCR, COG1649
NOS7524_RS13320	COG0277	FAD linked oxidase domain protein
NOS7524_RS13330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NOS7524_RS13335	COG0187	DNA topoisomerase II activity
NOS7524_RS13335	COG1372	Participates in initiation and elongation during chromosome replication
NOS7524_RS13340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOS7524_RS13345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NOS7524_RS13350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NOS7524_RS13370	COG3335	DDE superfamily endonuclease
NOS7524_RS13375	COG0347	Belongs to the P(II) protein family
NOS7524_RS13395	COG1136	(ABC) transporter
NOS7524_RS13395	COG0577	efflux transmembrane transporter activity
NOS7524_RS13410	COG0095	Lipoate-protein ligase
NOS7524_RS13415	COG0440	acetolactate synthase activity
NOS7524_RS13430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NOS7524_RS13475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NOS7524_RS13490	COG1950	PFAM Membrane protein of
NOS7524_RS13510	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS13515	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NOS7524_RS13560	COG0779	Required for maturation of 30S ribosomal subunits
NOS7524_RS13565	COG0195	Participates in both transcription termination and antitermination
NOS7524_RS13580	COG3266	domain, Protein
NOS7524_RS13580	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NOS7524_RS13595	COG1361	Conserved repeat domain
NOS7524_RS13620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NOS7524_RS13625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NOS7524_RS13630	COG1216	Glycosyl transferase, family 2
NOS7524_RS13635	COG0335	large ribosomal subunit rRNA binding
NOS7524_RS13645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NOS7524_RS13650	COG0250	Participates in transcription elongation, termination and antitermination
NOS7524_RS13655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NOS7524_RS13660	COG0081	regulation of translation
NOS7524_RS13665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NOS7524_RS13670	COG0222	ribosome binding
NOS7524_RS13690	COG1063	alcohol dehydrogenase
NOS7524_RS13730	COG3604	Transcriptional regulator
NOS7524_RS13745	COG0612	Peptidase, M16
NOS7524_RS13750	COG3001	Fructosamine kinase
NOS7524_RS13760	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NOS7524_RS13765	COG3852	Histidine kinase
NOS7524_RS13775	COG0589	response to stress
NOS7524_RS13780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NOS7524_RS13785	COG0268	Binds directly to 16S ribosomal RNA
NOS7524_RS13790	COG0084	hydrolase, TatD family'
NOS7524_RS13795	COG0085	RNA polymerase activity
NOS7524_RS13800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NOS7524_RS13805	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NOS7524_RS13810	COG1543	Belongs to the glycosyl hydrolase 57 family
NOS7524_RS13820	COG3258	Cytochrome c
NOS7524_RS13825	COG0723	plastoquinol--plastocyanin reductase activity
NOS7524_RS13835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NOS7524_RS13840	COG0805	protein transport
NOS7524_RS13865	COG0587	DNA-directed DNA polymerase activity
NOS7524_RS13870	COG0154	amidase activity
NOS7524_RS13880	COG1073	alpha beta
NOS7524_RS13895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NOS7524_RS13940	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS13945	COG1619	proteins homologs of microcin C7 resistance protein MccF
NOS7524_RS13950	COG1653	transport
NOS7524_RS13955	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NOS7524_RS13965	COG0415	Belongs to the DNA photolyase family
NOS7524_RS13970	COG3338	carbonate dehydratase activity
NOS7524_RS14005	COG2124	cytochrome p450
NOS7524_RS14030	COG2202	Pas domain
NOS7524_RS14030	COG2205	protein histidine kinase activity
NOS7524_RS14070	COG2010	Cytochrome c
NOS7524_RS14085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NOS7524_RS14085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NOS7524_RS14090	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS14130	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
NOS7524_RS14135	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
NOS7524_RS14150	COG0017	Asparaginyl-tRNA synthetase
NOS7524_RS14170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NOS7524_RS14185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NOS7524_RS14190	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NOS7524_RS14200	COG0601	transmembrane transport
NOS7524_RS14205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NOS7524_RS14220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NOS7524_RS14230	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NOS7524_RS14240	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NOS7524_RS14245	COG0573	inorganic phosphate transmembrane transporter activity
NOS7524_RS14250	COG0581	inorganic phosphate transmembrane transporter activity
NOS7524_RS14255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NOS7524_RS14260	COG1176	ABC-type spermidine putrescine transport system, permease component I
NOS7524_RS14265	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NOS7524_RS14270	COG3842	ATPase activity
NOS7524_RS14275	COG0768	penicillin binding
NOS7524_RS14280	COG0848	biopolymer transport protein
NOS7524_RS14285	COG0811	peptide transport
NOS7524_RS14315	COG0784	Response regulator, receiver
NOS7524_RS14315	COG2198	Histidine kinase
NOS7524_RS14315	COG0643	Histidine kinase
NOS7524_RS14320	COG2201	protein-glutamate methylesterase activity
NOS7524_RS14325	COG3852	Histidine kinase
NOS7524_RS14335	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS14340	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NOS7524_RS14345	COG0459	protein refolding
NOS7524_RS14375	COG0556	nucleotide-excision repair
NOS7524_RS14390	COG0504	CTP synthase activity
NOS7524_RS14395	COG4991	sh3 domain protein
NOS7524_RS14395	COG3103	Sh3 type 3 domain protein
NOS7524_RS14395	COG0860	N-Acetylmuramoyl-L-alanine amidase
NOS7524_RS14400	COG0860	N-Acetylmuramoyl-L-alanine amidase
NOS7524_RS14420	COG1834	amidinotransferase
NOS7524_RS14485	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NOS7524_RS14495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NOS7524_RS14510	COG0527	aspartate kinase activity
NOS7524_RS14520	COG1196	nuclear chromosome segregation
NOS7524_RS14550	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NOS7524_RS14555	COG1940	carbohydrate kinase activity
NOS7524_RS14565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NOS7524_RS14570	COG0492	ferredoxin-NADP+ reductase activity
NOS7524_RS14580	COG1803	Methylglyoxal synthase
NOS7524_RS14580	COG1597	lipid kinase activity
NOS7524_RS14600	COG1116	anion transmembrane transporter activity
NOS7524_RS14605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NOS7524_RS14605	COG1116	anion transmembrane transporter activity
NOS7524_RS14610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NOS7524_RS14615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NOS7524_RS14620	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NOS7524_RS14625	COG0784	Response regulator, receiver
NOS7524_RS14625	COG5002	protein histidine kinase activity
NOS7524_RS14625	COG2205	protein histidine kinase activity
NOS7524_RS14630	COG4251	negative regulation of phosphorylation
NOS7524_RS14630	COG2203	Gaf domain
NOS7524_RS14630	COG3706	GGDEF domain
NOS7524_RS14630	COG5001	Diguanylate cyclase
NOS7524_RS14635	COG0539	negative regulation of cytoplasmic translation
NOS7524_RS14640	COG0412	Dienelactone hydrolase
NOS7524_RS14645	COG2188	Transcriptional regulator
NOS7524_RS14710	COG0778	Nitroreductase
NOS7524_RS14720	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NOS7524_RS14725	COG0740	serine-type endopeptidase activity
NOS7524_RS14730	COG0544	peptidyl-prolyl cis-trans isomerase activity
NOS7524_RS14740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NOS7524_RS14745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NOS7524_RS14750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NOS7524_RS14760	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS14765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NOS7524_RS14770	COG4251	negative regulation of phosphorylation
NOS7524_RS14775	COG0784	Response regulator, receiver
NOS7524_RS14785	COG1132	(ABC) transporter
NOS7524_RS14790	COG0515	serine threonine protein kinase
NOS7524_RS14790	COG3266	domain, Protein
NOS7524_RS14795	COG4636	protein conserved in cyanobacteria
NOS7524_RS14805	COG0515	serine threonine protein kinase
NOS7524_RS14805	COG3266	domain, Protein
NOS7524_RS14855	COG1836	PFAM Integral membrane protein DUF92
NOS7524_RS14880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NOS7524_RS14900	COG4191	Histidine kinase
NOS7524_RS14905	COG1007	ATP synthesis coupled electron transport
NOS7524_RS14910	COG1074	ATP-dependent DNA helicase activity
NOS7524_RS14915	COG0826	peptidase U32
NOS7524_RS14920	COG0640	Transcriptional regulator
NOS7524_RS14925	COG3118	belongs to the thioredoxin family
NOS7524_RS14930	COG0778	Nitroreductase
NOS7524_RS14935	COG0625	glutathione transferase activity
NOS7524_RS14940	COG3631	Ketosteroid isomerase-related protein
NOS7524_RS14950	COG1657	PFAM Prenyltransferase squalene oxidase
NOS7524_RS14975	COG0038	chloride channel
NOS7524_RS15095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NOS7524_RS15095	COG2205	protein histidine kinase activity
NOS7524_RS15105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NOS7524_RS15110	COG3437	response regulator, receiver
NOS7524_RS15110	COG3850	Histidine kinase
NOS7524_RS15110	COG4999	Histidine kinase
NOS7524_RS15110	COG2205	protein histidine kinase activity
NOS7524_RS15130	COG2267	carboxylic ester hydrolase activity
NOS7524_RS15140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NOS7524_RS15145	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NOS7524_RS15155	COG0505	Belongs to the CarA family
NOS7524_RS15165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NOS7524_RS15205	COG3852	Histidine kinase
NOS7524_RS15215	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NOS7524_RS15230	COG1012	belongs to the aldehyde dehydrogenase family
NOS7524_RS15230	COG1454	alcohol dehydrogenase
NOS7524_RS15235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NOS7524_RS15240	COG1882	Formate acetyltransferase
NOS7524_RS15250	COG1012	belongs to the aldehyde dehydrogenase family
NOS7524_RS15260	COG2226	methyltransferase
NOS7524_RS15265	COG1233	COG1233 Phytoene dehydrogenase and related
NOS7524_RS15270	COG3266	domain, Protein
NOS7524_RS15270	COG0515	serine threonine protein kinase
NOS7524_RS15275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NOS7524_RS15310	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NOS7524_RS15325	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS15330	COG5002	protein histidine kinase activity
NOS7524_RS15340	COG4251	negative regulation of phosphorylation
NOS7524_RS15345	COG0784	Response regulator, receiver
NOS7524_RS15350	COG5002	protein histidine kinase activity
NOS7524_RS15380	COG0535	radical SAM domain protein
NOS7524_RS15405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NOS7524_RS15435	COG1785	Belongs to the alkaline phosphatase family
NOS7524_RS15440	COG0668	transmembrane transport
NOS7524_RS15450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NOS7524_RS15540	COG3547	Transposase (IS116 IS110 IS902 family)
NOS7524_RS15725	COG1842	Phage shock protein A
NOS7524_RS15730	COG1842	Phage shock protein A
NOS7524_RS15735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NOS7524_RS15745	COG2912	Transglutaminase-like superfamily
NOS7524_RS15815	COG0572	uridine kinase
NOS7524_RS15825	COG0010	Belongs to the arginase family
NOS7524_RS15860	COG0297	glycogen (starch) synthase activity
NOS7524_RS15865	COG5433	transposase activity
NOS7524_RS15875	COG0436	Aminotransferase
NOS7524_RS15910	COG4774	siderophore transport
NOS7524_RS15915	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NOS7524_RS15925	COG1132	(ABC) transporter
NOS7524_RS15930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NOS7524_RS15955	COG1120	ATPase activity
NOS7524_RS15960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOS7524_RS15965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOS7524_RS15970	COG1132	(ABC) transporter
NOS7524_RS15975	COG1132	(ABC) transporter
NOS7524_RS16005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NOS7524_RS16020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NOS7524_RS16040	COG0716	FMN binding
NOS7524_RS16045	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NOS7524_RS16090	COG1528	Iron-storage protein
NOS7524_RS16105	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NOS7524_RS16120	COG0314	molybdopterin synthase activity
NOS7524_RS16130	COG1335	isochorismatase
NOS7524_RS16135	COG0402	S-adenosylhomocysteine deaminase activity
NOS7524_RS16140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NOS7524_RS16145	COG0456	acetyltransferase
NOS7524_RS16145	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NOS7524_RS16190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NOS7524_RS16195	COG1496	oxidoreductase activity
NOS7524_RS16200	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NOS7524_RS16200	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NOS7524_RS16205	COG0739	heme binding
NOS7524_RS16205	COG0741	lytic transglycosylase activity
NOS7524_RS16205	COG1196	nuclear chromosome segregation
NOS7524_RS16225	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NOS7524_RS16245	COG2204	response regulator
NOS7524_RS16250	COG2226	methyltransferase
NOS7524_RS16255	COG4399	Belongs to the UPF0754 family
NOS7524_RS16265	COG0154	amidase activity
NOS7524_RS16270	COG0385	Bile acid
NOS7524_RS16275	COG0861	Integral membrane protein TerC family
NOS7524_RS16280	COG0105	UTP biosynthetic process
NOS7524_RS16285	COG1166	arginine decarboxylase activity
NOS7524_RS16290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NOS7524_RS16305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NOS7524_RS16305	COG0574	Belongs to the PEP-utilizing enzyme family
NOS7524_RS16310	COG1285	pathogenesis
NOS7524_RS16345	COG3540	Alkaline phosphatase
NOS7524_RS16365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NOS7524_RS16370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NOS7524_RS16375	COG4956	integral membrane protein (PIN domain superfamily)
NOS7524_RS16390	COG2304	oxidoreductase activity
NOS7524_RS16395	COG2304	oxidoreductase activity
NOS7524_RS16400	COG0740	serine-type endopeptidase activity
NOS7524_RS16405	COG0740	serine-type endopeptidase activity
NOS7524_RS16450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NOS7524_RS16455	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NOS7524_RS16475	COG2124	cytochrome p450
NOS7524_RS16480	COG1192	Involved in chromosome partitioning
NOS7524_RS16520	COG0500	methyltransferase
NOS7524_RS16540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NOS7524_RS16570	COG2274	protein secretion by the type I secretion system
NOS7524_RS16575	COG0124	histidyl-tRNA synthetase
NOS7524_RS16605	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NOS7524_RS16610	COG5398	heme oxygenase
NOS7524_RS16615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NOS7524_RS16620	COG2261	transglycosylase associated protein
NOS7524_RS16625	COG3546	catalase activity
NOS7524_RS16635	COG0138	bifunctional purine biosynthesis protein purh
NOS7524_RS16645	COG0697	spore germination
NOS7524_RS16655	COG0489	protein tyrosine kinase activity
NOS7524_RS16660	COG0484	heat shock protein binding
NOS7524_RS16685	COG0628	permease
NOS7524_RS16695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NOS7524_RS16700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NOS7524_RS16705	COG0416	fatty acid biosynthetic process
NOS7524_RS16710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NOS7524_RS16715	COG1122	ATPase activity
NOS7524_RS16730	COG0494	nUDIX hydrolase
NOS7524_RS16735	COG4581	dead DEAH box helicase
NOS7524_RS16740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NOS7524_RS16745	COG1799	cell septum assembly
NOS7524_RS16750	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NOS7524_RS16760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NOS7524_RS16765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NOS7524_RS16770	COG1160	GTP binding
NOS7524_RS16775	COG1408	metallophosphoesterase
NOS7524_RS16780	COG4638	Rieske (2fe-2S)
NOS7524_RS16790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NOS7524_RS16815	COG0237	dephospho-CoA kinase activity
NOS7524_RS16820	COG3903	Transcriptional regulator
NOS7524_RS16820	COG2319	Wd-40 repeat
NOS7524_RS16840	COG4106	trans-aconitate 2-methyltransferase activity
NOS7524_RS16850	COG2124	cytochrome p450
NOS7524_RS16870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NOS7524_RS16885	COG0217	transcriptional regulatory protein
NOS7524_RS16900	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NOS7524_RS16915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOS7524_RS16920	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NOS7524_RS16945	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS16960	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS16970	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS16975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NOS7524_RS16980	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
NOS7524_RS16985	COG2211	Major facilitator Superfamily
NOS7524_RS16990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NOS7524_RS16995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NOS7524_RS17020	COG4279	zinc finger
NOS7524_RS17025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NOS7524_RS17035	COG1185	polyribonucleotide nucleotidyltransferase activity
NOS7524_RS17060	COG2217	Heavy metal translocating P-type atpase
NOS7524_RS17090	COG3540	Alkaline phosphatase
NOS7524_RS17110	COG0628	permease
NOS7524_RS17120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NOS7524_RS17125	COG0134	indole-3-glycerol-phosphate synthase activity
NOS7524_RS17150	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS17155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NOS7524_RS17160	COG0702	epimerase
NOS7524_RS17170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NOS7524_RS17180	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS17195	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NOS7524_RS17210	COG0133	tryptophan synthase activity
NOS7524_RS17215	COG0023	Translation Initiation Factor
NOS7524_RS17225	COG2226	methyltransferase
NOS7524_RS17245	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS17255	COG2304	oxidoreductase activity
NOS7524_RS17265	COG0167	dihydroorotate dehydrogenase activity
NOS7524_RS17275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS17280	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS17285	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS17290	COG1773	rubredoxin
NOS7524_RS17295	COG4447	cellulose binding
NOS7524_RS17350	COG1191	sigma factor activity
NOS7524_RS17385	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NOS7524_RS17390	COG0189	ligase activity
NOS7524_RS17395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NOS7524_RS17405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NOS7524_RS17435	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NOS7524_RS17460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NOS7524_RS17495	COG0706	membrane insertase activity
NOS7524_RS17505	COG0594	ribonuclease P activity
NOS7524_RS17545	COG1132	(ABC) transporter
NOS7524_RS17560	COG1702	phosphate starvation-inducible protein PhoH
NOS7524_RS17565	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NOS7524_RS17575	COG0228	four-way junction DNA binding
NOS7524_RS17585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NOS7524_RS17590	COG0006	proline dipeptidase activity
NOS7524_RS17600	COG0384	phenazine biosynthesis protein PhzF
NOS7524_RS17625	COG3547	Transposase (IS116 IS110 IS902 family)
NOS7524_RS17635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NOS7524_RS17675	COG2198	Histidine kinase
NOS7524_RS17675	COG2198	Histidine kinase
NOS7524_RS17675	COG0643	Histidine kinase
NOS7524_RS17675	COG0784	Response regulator, receiver
NOS7524_RS17675	COG0643	Histidine kinase
NOS7524_RS17675	COG0784	Response regulator, receiver
NOS7524_RS17680	COG0840	transmembrane signaling receptor activity
NOS7524_RS17700	COG0784	Response regulator, receiver
NOS7524_RS17710	COG0037	tRNA processing
NOS7524_RS17720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NOS7524_RS17740	COG0439	Biotin carboxylase
NOS7524_RS17760	COG0515	serine threonine protein kinase
NOS7524_RS17790	COG0109	protoheme IX farnesyltransferase activity
NOS7524_RS17800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NOS7524_RS17805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NOS7524_RS17810	COG1845	cytochrome c oxidase, subunit III
NOS7524_RS17830	COG0686	Belongs to the AlaDH PNT family
NOS7524_RS17850	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
NOS7524_RS17875	COG1606	tRNA processing
NOS7524_RS17880	COG2205	protein histidine kinase activity
NOS7524_RS17880	COG2198	Histidine kinase
NOS7524_RS17880	COG0784	Response regulator, receiver
NOS7524_RS17895	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NOS7524_RS17910	COG1271	oxidase subunit
NOS7524_RS17915	COG0157	Belongs to the NadC ModD family
NOS7524_RS17945	COG3854	ATPases associated with a variety of cellular activities
NOS7524_RS17960	COG5002	protein histidine kinase activity
NOS7524_RS17960	COG0784	Response regulator, receiver
NOS7524_RS17975	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NOS7524_RS17980	COG3621	Patatin-like phospholipase
NOS7524_RS17985	COG0802	atpase or kinase
NOS7524_RS17990	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NOS7524_RS17995	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NOS7524_RS18000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NOS7524_RS18015	COG2274	protein secretion by the type I secretion system
NOS7524_RS18035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NOS7524_RS18040	COG0713	ATP synthesis coupled electron transport
NOS7524_RS18045	COG0839	Belongs to the complex I subunit 6 family
NOS7524_RS18050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS18055	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NOS7524_RS18060	COG0372	Belongs to the citrate synthase family
NOS7524_RS18065	COG2062	phosphohistidine phosphatase, SixA
NOS7524_RS18095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NOS7524_RS18105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NOS7524_RS18110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NOS7524_RS18120	COG0123	including yeast histone deacetylase and acetoin utilization protein
NOS7524_RS18135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NOS7524_RS18140	COG2205	protein histidine kinase activity
NOS7524_RS18140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NOS7524_RS18140	COG0784	Response regulator, receiver
NOS7524_RS18140	COG2198	Histidine kinase
NOS7524_RS18145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NOS7524_RS18165	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NOS7524_RS18175	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NOS7524_RS18185	COG1051	belongs to the nudix hydrolase family
NOS7524_RS18190	COG0628	permease
NOS7524_RS18205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NOS7524_RS18215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NOS7524_RS18225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NOS7524_RS18255	COG3547	Transposase (IS116 IS110 IS902 family)
NOS7524_RS18260	COG1489	DNA binding
NOS7524_RS18265	COG3265	gluconokinase activity
NOS7524_RS18300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NOS7524_RS18305	COG1733	regulation of RNA biosynthetic process
NOS7524_RS18335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NOS7524_RS18345	COG1845	cytochrome c oxidase, subunit III
NOS7524_RS18350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NOS7524_RS18370	COG0443	Heat shock 70 kDa protein
NOS7524_RS18385	COG0863	Belongs to the N(4) N(6)-methyltransferase family
NOS7524_RS18395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NOS7524_RS18435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NOS7524_RS18440	COG2205	protein histidine kinase activity
NOS7524_RS18450	COG4251	negative regulation of phosphorylation
NOS7524_RS18455	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NOS7524_RS18480	COG0300	oxidoreductase activity
NOS7524_RS18530	COG3335	DDE superfamily endonuclease
NOS7524_RS18550	COG4636	protein conserved in cyanobacteria
NOS7524_RS18570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NOS7524_RS18575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NOS7524_RS18585	COG1032	radical SAM domain protein
NOS7524_RS18590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NOS7524_RS18595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NOS7524_RS18610	COG0121	glutamine amidotransferase
NOS7524_RS18625	COG3266	domain, Protein
NOS7524_RS18625	COG0515	serine threonine protein kinase
NOS7524_RS18655	COG2217	Heavy metal translocating P-type atpase
NOS7524_RS18665	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NOS7524_RS18690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NOS7524_RS18705	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NOS7524_RS18740	COG1136	(ABC) transporter
NOS7524_RS18740	COG0577	efflux transmembrane transporter activity
NOS7524_RS18755	COG1615	UPF0182 protein
NOS7524_RS18770	COG1473	amidohydrolase
NOS7524_RS18775	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NOS7524_RS18780	COG0515	serine threonine protein kinase
NOS7524_RS18785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NOS7524_RS18795	COG1217	gtp-binding protein TYPA
NOS7524_RS18845	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
NOS7524_RS18880	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NOS7524_RS18890	COG0484	heat shock protein binding
NOS7524_RS18895	COG0450	alkyl hydroperoxide reductase
NOS7524_RS18900	COG0450	alkyl hydroperoxide reductase
NOS7524_RS18915	COG0390	transport system, permease component
NOS7524_RS18935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NOS7524_RS18935	COG4191	Histidine kinase
NOS7524_RS18940	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
NOS7524_RS18950	COG4106	trans-aconitate 2-methyltransferase activity
NOS7524_RS18970	COG1573	uracil-dna glycosylase
NOS7524_RS18980	COG0284	orotidine-5'-phosphate decarboxylase activity
NOS7524_RS18985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NOS7524_RS19000	COG0484	heat shock protein binding
NOS7524_RS19015	COG0681	Belongs to the peptidase S26 family
NOS7524_RS19050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NOS7524_RS19055	COG1446	asparaginase
NOS7524_RS19060	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NOS7524_RS19065	COG3437	response regulator, receiver
NOS7524_RS19070	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NOS7524_RS19070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NOS7524_RS19095	COG0045	succinate-CoA ligase (ADP-forming) activity
NOS7524_RS19105	COG2988	succinylglutamate desuccinylase activity
NOS7524_RS19110	COG1770	oligopeptidase
NOS7524_RS19120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NOS7524_RS19125	COG0702	epimerase
NOS7524_RS19130	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NOS7524_RS19135	COG2211	Major facilitator Superfamily
NOS7524_RS19175	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NOS7524_RS19190	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NOS7524_RS19195	COG0408	coproporphyrinogen oxidase activity
NOS7524_RS19200	COG5398	heme oxygenase
NOS7524_RS19205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NOS7524_RS19210	COG2264	protein methyltransferase activity
NOS7524_RS19215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NOS7524_RS19230	COG0793	Belongs to the peptidase S41A family
NOS7524_RS19235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NOS7524_RS19240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NOS7524_RS19255	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS19265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NOS7524_RS19265	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NOS7524_RS19280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NOS7524_RS19300	COG4585	Histidine kinase
NOS7524_RS19305	COG2197	response regulator
NOS7524_RS19315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NOS7524_RS19335	COG3932	Exopolysaccharide synthesis, ExoD
NOS7524_RS19420	COG1252	NADH dehydrogenase
NOS7524_RS19425	COG1252	NADH dehydrogenase
NOS7524_RS19450	COG1136	(ABC) transporter
NOS7524_RS19450	COG0577	efflux transmembrane transporter activity
NOS7524_RS19465	COG0583	DNA-binding transcription factor activity
NOS7524_RS19475	COG0714	Associated with various cellular activities
NOS7524_RS19510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NOS7524_RS19540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NOS7524_RS19550	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NOS7524_RS19550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NOS7524_RS19570	COG1131	(ABC) transporter
NOS7524_RS19580	COG0393	Putative heavy-metal-binding
NOS7524_RS19600	COG0719	Fe-S assembly protein
NOS7524_RS19605	COG0396	ATPase activity
NOS7524_RS19610	COG0719	Fe-S assembly protein
NOS7524_RS19615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NOS7524_RS19635	COG0432	Pfam Uncharacterised protein family UPF0047
NOS7524_RS19650	COG0702	epimerase
NOS7524_RS19655	COG0436	Aminotransferase
NOS7524_RS19660	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
NOS7524_RS19670	COG3852	Histidine kinase
NOS7524_RS19675	COG3842	ATPase activity
NOS7524_RS19685	COG0515	serine threonine protein kinase
NOS7524_RS19690	COG0538	isocitrate dehydrogenase activity
NOS7524_RS19710	COG0357	Ribosomal RNA small subunit methyltransferase G
NOS7524_RS19730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NOS7524_RS19755	COG3118	belongs to the thioredoxin family
NOS7524_RS19760	COG0516	GMP reductase activity
NOS7524_RS19765	COG1193	negative regulation of DNA recombination
NOS7524_RS19780	COG0484	heat shock protein binding
NOS7524_RS19785	COG0443	Heat shock 70 kDa protein
NOS7524_RS19790	COG2234	aminopeptidase activity
NOS7524_RS19795	COG3781	membrane
NOS7524_RS19820	COG0024	Methionine aminopeptidase
NOS7524_RS19830	COG0612	Peptidase, M16
NOS7524_RS19890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NOS7524_RS19930	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NOS7524_RS19935	COG2201	protein-glutamate methylesterase activity
NOS7524_RS19960	COG2203	Gaf domain
NOS7524_RS19960	COG3706	GGDEF domain
NOS7524_RS19960	COG4251	negative regulation of phosphorylation
NOS7524_RS19960	COG5001	Diguanylate cyclase
NOS7524_RS19985	COG0411	ABC transporter
NOS7524_RS20020	COG0837	glucose binding
NOS7524_RS20030	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NOS7524_RS20055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NOS7524_RS20060	COG1121	(ABC) transporter
NOS7524_RS20065	COG0803	Belongs to the bacterial solute-binding protein 9 family
NOS7524_RS20080	COG1160	GTP binding
NOS7524_RS20090	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NOS7524_RS20110	COG2226	methyltransferase
NOS7524_RS20130	COG0515	serine threonine protein kinase
NOS7524_RS20130	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS20135	COG1063	alcohol dehydrogenase
NOS7524_RS20140	COG0306	phosphate transporter
NOS7524_RS20145	COG0697	spore germination
NOS7524_RS20175	COG3852	Histidine kinase
NOS7524_RS20180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NOS7524_RS20195	COG0515	serine threonine protein kinase
NOS7524_RS20195	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS20205	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NOS7524_RS20210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NOS7524_RS20225	COG0784	Response regulator, receiver
NOS7524_RS20245	COG0564	pseudouridine synthase activity
NOS7524_RS20260	COG0237	dephospho-CoA kinase activity
NOS7524_RS20265	COG1413	lyase activity
NOS7524_RS20270	COG1413	lyase activity
NOS7524_RS20285	COG0237	dephospho-CoA kinase activity
NOS7524_RS20290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NOS7524_RS20295	COG1413	lyase activity
NOS7524_RS20300	COG1413	lyase activity
NOS7524_RS20305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NOS7524_RS20310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NOS7524_RS20315	COG0237	dephospho-CoA kinase activity
NOS7524_RS20320	COG0237	dephospho-CoA kinase activity
NOS7524_RS20345	COG1012	belongs to the aldehyde dehydrogenase family
NOS7524_RS20385	COG0426	domain, Protein
NOS7524_RS20385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NOS7524_RS20390	COG0426	domain, Protein
NOS7524_RS20390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NOS7524_RS20400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NOS7524_RS20410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NOS7524_RS20415	COG0501	Belongs to the peptidase M48B family
NOS7524_RS20435	COG2385	sporulation resulting in formation of a cellular spore
NOS7524_RS20470	COG0824	Thioesterase
NOS7524_RS20480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NOS7524_RS20510	COG0070	glutamate synthase
NOS7524_RS20510	COG0069	glutamate synthase activity
NOS7524_RS20510	COG0067	glutamate synthase
NOS7524_RS20525	COG0316	Belongs to the HesB IscA family
NOS7524_RS20530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NOS7524_RS20535	COG0049	tRNA binding
NOS7524_RS20540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NOS7524_RS20545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NOS7524_RS20550	COG0051	transcription antitermination factor activity, RNA binding
NOS7524_RS20555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NOS7524_RS20560	COG0077	Prephenate dehydratase
NOS7524_RS20570	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NOS7524_RS20575	COG1530	ribonuclease E activity
NOS7524_RS20595	COG0436	Aminotransferase
NOS7524_RS20605	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NOS7524_RS20620	COG0724	RNA recognition motif
NOS7524_RS20645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NOS7524_RS20665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NOS7524_RS20670	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS20680	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NOS7524_RS20685	COG0271	Belongs to the BolA IbaG family
NOS7524_RS20695	COG1404	Belongs to the peptidase S8 family
NOS7524_RS20695	COG4935	Belongs to the peptidase S8 family
NOS7524_RS20705	COG0590	tRNA wobble adenosine to inosine editing
NOS7524_RS20710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NOS7524_RS20715	COG1494	fructose-1,6-bisphosphatase
NOS7524_RS20720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NOS7524_RS20725	COG0640	Transcriptional regulator
NOS7524_RS20750	COG0166	Belongs to the GPI family
NOS7524_RS20780	COG0039	L-malate dehydrogenase activity
NOS7524_RS20800	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NOS7524_RS20820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NOS7524_RS20830	COG0515	serine threonine protein kinase
NOS7524_RS20835	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NOS7524_RS20865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NOS7524_RS20870	COG3547	Transposase (IS116 IS110 IS902 family)
NOS7524_RS20875	COG0515	serine threonine protein kinase
NOS7524_RS20875	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS20910	COG0395	ABC-type sugar transport system, permease component
NOS7524_RS20915	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NOS7524_RS20920	COG5322	oxidoreductase activity
NOS7524_RS20925	COG0825	malonyl-CoA metabolic process
NOS7524_RS20930	COG0300	oxidoreductase activity
NOS7524_RS20935	COG0302	gtp cyclohydrolase
NOS7524_RS20940	COG0135	phosphoribosylanthranilate isomerase activity
NOS7524_RS20950	COG2337	Toxic component of a toxin-antitoxin (TA) module
NOS7524_RS20995	COG4636	protein conserved in cyanobacteria
NOS7524_RS21000	COG0285	dihydrofolate synthase activity
NOS7524_RS21025	COG0793	Belongs to the peptidase S41A family
NOS7524_RS21030	COG1215	transferase activity, transferring glycosyl groups
NOS7524_RS21080	COG0243	molybdopterin cofactor binding
NOS7524_RS21085	COG1116	anion transmembrane transporter activity
NOS7524_RS21090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NOS7524_RS21090	COG1116	anion transmembrane transporter activity
NOS7524_RS21095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NOS7524_RS21100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NOS7524_RS21110	COG0723	plastoquinol--plastocyanin reductase activity
NOS7524_RS21130	COG0583	DNA-binding transcription factor activity
NOS7524_RS21135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NOS7524_RS21165	COG1201	RNA secondary structure unwinding
NOS7524_RS21175	COG0792	nuclease activity
NOS7524_RS21185	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NOS7524_RS21195	COG0569	domain protein
NOS7524_RS21200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NOS7524_RS21205	COG2226	methyltransferase
NOS7524_RS21215	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NOS7524_RS21225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NOS7524_RS21245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NOS7524_RS21255	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NOS7524_RS21265	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NOS7524_RS21275	COG2084	Dehydrogenase
NOS7524_RS21280	COG3852	Histidine kinase
NOS7524_RS21285	COG0701	Predicted permease
NOS7524_RS21315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NOS7524_RS21330	COG2022	thiamine diphosphate biosynthetic process
NOS7524_RS21330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NOS7524_RS21350	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS21370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NOS7524_RS21375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NOS7524_RS21380	COG1136	(ABC) transporter
NOS7524_RS21395	COG0546	phosphoglycolate phosphatase activity
NOS7524_RS21400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NOS7524_RS21405	COG3631	Ketosteroid isomerase-related protein
NOS7524_RS21440	COG2197	response regulator
NOS7524_RS21450	COG2884	Cell division ATP-binding protein ftsE
NOS7524_RS21475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NOS7524_RS21475	COG1754	DNA topoisomerase type I activity
NOS7524_RS21485	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NOS7524_RS21495	COG1480	7TM receptor with intracellular HD hydrolase
NOS7524_RS21500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NOS7524_RS21515	COG2124	cytochrome p450
NOS7524_RS21540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NOS7524_RS21575	COG0673	inositol 2-dehydrogenase activity
NOS7524_RS21585	COG0028	Belongs to the TPP enzyme family
NOS7524_RS21600	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NOS7524_RS21605	COG0431	NADPH-dependent FMN reductase
NOS7524_RS21610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NOS7524_RS21665	COG1429	ligase activity, forming nitrogen-metal bonds
NOS7524_RS21695	COG1858	cytochrome C peroxidase
NOS7524_RS21710	COG4771	TonB-dependent receptor
NOS7524_RS21720	COG4206	TonB-dependent receptor
NOS7524_RS21735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOS7524_RS21740	COG1120	ATPase activity
NOS7524_RS21745	COG1122	ATPase activity
NOS7524_RS21750	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NOS7524_RS21760	COG4771	TonB-dependent receptor
NOS7524_RS21770	COG1429	ligase activity, forming nitrogen-metal bonds
NOS7524_RS21780	COG1598	PFAM Uncharacterised protein family UPF0150
NOS7524_RS21785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NOS7524_RS21810	COG1247	-acetyltransferase
NOS7524_RS21815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NOS7524_RS21825	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NOS7524_RS21845	COG0586	Pfam SNARE associated Golgi protein
NOS7524_RS21850	COG0673	inositol 2-dehydrogenase activity
NOS7524_RS21855	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NOS7524_RS21860	COG1253	flavin adenine dinucleotide binding
NOS7524_RS21880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NOS7524_RS21890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NOS7524_RS21895	COG0552	protein localization to endoplasmic reticulum
NOS7524_RS21900	COG2208	phosphoserine phosphatase activity
NOS7524_RS21905	COG5634	Uncharacterized conserved protein (DUF2278)
NOS7524_RS21920	COG0424	maF-like protein
NOS7524_RS21930	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NOS7524_RS21950	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
NOS7524_RS21955	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS21960	COG1899	peptidyl-lysine modification to peptidyl-hypusine
NOS7524_RS21990	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NOS7524_RS22000	COG0445	tRNA wobble uridine modification
NOS7524_RS22010	COG0126	phosphoglycerate kinase activity
NOS7524_RS22015	COG0589	response to stress
NOS7524_RS22060	COG2066	Belongs to the glutaminase family
NOS7524_RS22070	COG2885	chlorophyll binding
NOS7524_RS22075	COG2885	chlorophyll binding
NOS7524_RS22090	COG0018	arginyl-trna synthetase
NOS7524_RS22095	COG0517	IMP dehydrogenase activity
NOS7524_RS22095	COG1994	Peptidase M50
NOS7524_RS22105	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
NOS7524_RS22135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NOS7524_RS22160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NOS7524_RS22165	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NOS7524_RS22175	COG0724	RNA recognition motif
NOS7524_RS22195	COG0824	Thioesterase
NOS7524_RS22205	COG1748	Saccharopine dehydrogenase
NOS7524_RS22215	COG1459	type II secretion system
NOS7524_RS22225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NOS7524_RS22230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NOS7524_RS22235	COG0443	Heat shock 70 kDa protein
NOS7524_RS22245	COG0484	heat shock protein binding
NOS7524_RS22255	COG1162	GTPase activity
NOS7524_RS22265	COG3266	domain, Protein
NOS7524_RS22265	COG0515	serine threonine protein kinase
NOS7524_RS22295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NOS7524_RS22305	COG1492	cobalamin metabolic process
NOS7524_RS22330	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
NOS7524_RS22345	COG0316	Belongs to the HesB IscA family
NOS7524_RS22360	COG1090	epimerase
NOS7524_RS22365	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
NOS7524_RS22390	COG0515	serine threonine protein kinase
NOS7524_RS22390	COG3266	domain, Protein
NOS7524_RS22400	COG0575	Belongs to the CDS family
NOS7524_RS22410	COG1187	pseudouridine synthase activity
NOS7524_RS22415	COG1426	Protein conserved in bacteria
NOS7524_RS22420	COG1640	4-alpha-glucanotransferase
NOS7524_RS22435	COG0251	oxidation-reduction process
NOS7524_RS22440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NOS7524_RS22445	COG0426	domain, Protein
NOS7524_RS22445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NOS7524_RS22460	COG1160	GTP binding
NOS7524_RS22480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NOS7524_RS22480	COG0426	domain, Protein
NOS7524_RS22515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NOS7524_RS22530	COG0297	glycogen (starch) synthase activity
NOS7524_RS22535	COG0181	hydroxymethylbilane synthase activity
NOS7524_RS22545	COG1803	Methylglyoxal synthase
NOS7524_RS22545	COG1597	lipid kinase activity
NOS7524_RS22555	COG0723	plastoquinol--plastocyanin reductase activity
NOS7524_RS22570	COG1131	(ABC) transporter
NOS7524_RS22595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NOS7524_RS22595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NOS7524_RS22615	COG2909	trisaccharide binding
NOS7524_RS22640	COG0312	modulator of DNA gyrase
NOS7524_RS22655	COG0753	catalase activity
NOS7524_RS22660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NOS7524_RS22675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NOS7524_RS22700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NOS7524_RS22735	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
NOS7524_RS22745	COG0330	HflC and HflK could
NOS7524_RS22750	COG1515	deoxyribonuclease V activity
NOS7524_RS22755	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS22755	COG0515	serine threonine protein kinase
NOS7524_RS22810	COG2442	InterPro IPR007367
NOS7524_RS22920	COG1215	transferase activity, transferring glycosyl groups
NOS7524_RS22945	COG1472	Belongs to the glycosyl hydrolase 3 family
NOS7524_RS22950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NOS7524_RS22950	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
NOS7524_RS22955	COG1562	ergosterol biosynthetic process
NOS7524_RS22985	COG1253	flavin adenine dinucleotide binding
NOS7524_RS22990	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NOS7524_RS23015	COG1598	PFAM Uncharacterised protein family UPF0150
NOS7524_RS23040	COG0363	glucosamine-6-phosphate deaminase activity
NOS7524_RS23045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NOS7524_RS23075	COG0515	serine threonine protein kinase
NOS7524_RS23075	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS23090	COG1902	pentaerythritol trinitrate reductase activity
NOS7524_RS23105	COG4771	TonB-dependent receptor
NOS7524_RS23120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NOS7524_RS23120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NOS7524_RS23130	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
NOS7524_RS23140	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NOS7524_RS23150	COG3239	Fatty acid desaturase
NOS7524_RS23155	COG3239	Fatty acid desaturase
NOS7524_RS23180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NOS7524_RS23190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NOS7524_RS23205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NOS7524_RS23215	COG0517	IMP dehydrogenase activity
NOS7524_RS23215	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NOS7524_RS23215	COG0617	tRNA 3'-terminal CCA addition
NOS7524_RS23225	COG0488	(ABC) transporter
NOS7524_RS23230	COG3937	granule-associated protein
NOS7524_RS23235	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NOS7524_RS23240	COG0631	protein serine/threonine phosphatase activity
NOS7524_RS23250	COG0515	serine threonine protein kinase
NOS7524_RS23260	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NOS7524_RS23265	COG2205	protein histidine kinase activity
NOS7524_RS23275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NOS7524_RS23285	COG2226	methyltransferase
NOS7524_RS23295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NOS7524_RS23330	COG5002	protein histidine kinase activity
NOS7524_RS23350	COG1596	polysaccharide export
NOS7524_RS23355	COG3206	protein involved in exopolysaccharide biosynthesis
NOS7524_RS23355	COG0489	protein tyrosine kinase activity
NOS7524_RS23390	COG0463	Glycosyl transferase, family 2
NOS7524_RS23390	COG0457	Tetratricopeptide repeat
NOS7524_RS23395	COG0436	Aminotransferase
NOS7524_RS23405	COG1830	Aldolase
NOS7524_RS23415	COG2954	triphosphatase activity
NOS7524_RS23425	COG1049	propionate catabolic process, 2-methylcitrate cycle
NOS7524_RS23555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NOS7524_RS23570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NOS7524_RS23580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NOS7524_RS23590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NOS7524_RS23595	COG0189	ligase activity
NOS7524_RS23595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NOS7524_RS23600	COG4242	Belongs to the peptidase S51 family
NOS7524_RS23605	COG0336	Belongs to the RNA methyltransferase TrmD family
NOS7524_RS23610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NOS7524_RS23615	COG0747	negative chemotaxis
NOS7524_RS23620	COG1691	(AIR) carboxylase
NOS7524_RS23630	COG0165	Argininosuccinate lyase
NOS7524_RS23650	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NOS7524_RS23670	COG0783	Belongs to the Dps family
NOS7524_RS23675	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NOS7524_RS23680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOS7524_RS23690	COG0494	nUDIX hydrolase
NOS7524_RS23695	COG0516	GMP reductase activity
NOS7524_RS23695	COG0517	IMP dehydrogenase activity
NOS7524_RS23720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NOS7524_RS23725	COG0640	Transcriptional regulator
NOS7524_RS23730	COG1121	(ABC) transporter
NOS7524_RS23735	COG3443	Belongs to the bacterial solute-binding protein 9 family
NOS7524_RS23735	COG0803	Belongs to the bacterial solute-binding protein 9 family
NOS7524_RS23740	COG3659	wide pore channel activity
NOS7524_RS23755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NOS7524_RS23760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NOS7524_RS23765	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
NOS7524_RS23770	COG1027	Aspartate ammonia-lyase
NOS7524_RS23780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NOS7524_RS23800	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS23810	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NOS7524_RS23815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NOS7524_RS23820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NOS7524_RS23825	COG0395	ABC-type sugar transport system, permease component
NOS7524_RS23835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NOS7524_RS23845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NOS7524_RS23865	COG0741	lytic transglycosylase activity
NOS7524_RS23875	COG2264	protein methyltransferase activity
NOS7524_RS23880	COG0531	amino acid
NOS7524_RS23905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NOS7524_RS23910	COG1116	anion transmembrane transporter activity
NOS7524_RS23910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NOS7524_RS23920	COG0475	glutathione-regulated potassium exporter activity
NOS7524_RS23955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NOS7524_RS23960	COG0088	Forms part of the polypeptide exit tunnel
NOS7524_RS23965	COG0089	rRNA binding
NOS7524_RS23970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NOS7524_RS23975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NOS7524_RS23980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NOS7524_RS23985	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NOS7524_RS23990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NOS7524_RS23995	COG0255	Belongs to the universal ribosomal protein uL29 family
NOS7524_RS24000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NOS7524_RS24005	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NOS7524_RS24010	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NOS7524_RS24015	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NOS7524_RS24020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NOS7524_RS24025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NOS7524_RS24030	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NOS7524_RS24035	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NOS7524_RS24040	COG0200	Binds to the 23S rRNA
NOS7524_RS24045	COG0201	protein transport
NOS7524_RS24050	COG0563	adenylate kinase activity
NOS7524_RS24055	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NOS7524_RS24060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NOS7524_RS24065	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NOS7524_RS24070	COG0202	RNA polymerase activity
NOS7524_RS24075	COG0203	ribosomal protein L17
NOS7524_RS24080	COG0101	tRNA pseudouridine synthase activity
NOS7524_RS24085	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NOS7524_RS24090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NOS7524_RS24095	COG0254	rRNA binding
NOS7524_RS24100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NOS7524_RS24115	COG1002	Type II restriction enzyme, methylase subunits
NOS7524_RS24125	COG0488	(ABC) transporter
NOS7524_RS24130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NOS7524_RS24170	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS24180	COG1381	Involved in DNA repair and RecF pathway recombination
NOS7524_RS24185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NOS7524_RS24195	COG1006	Multisubunit Na H antiporter MnhC subunit
NOS7524_RS24200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NOS7524_RS24260	COG0799	negative regulation of ribosome biogenesis
NOS7524_RS24265	COG0297	glycogen (starch) synthase activity
NOS7524_RS24270	COG0583	DNA-binding transcription factor activity
NOS7524_RS24275	COG0129	dihydroxy-acid dehydratase activity
NOS7524_RS24280	COG1126	abc transporter atp-binding protein
NOS7524_RS24285	COG0765	amino acid transport
NOS7524_RS24290	COG4597	amino acid ABC transporter
NOS7524_RS24295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NOS7524_RS24310	COG0602	queuosine metabolic process
NOS7524_RS24315	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NOS7524_RS24335	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
NOS7524_RS24345	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
NOS7524_RS24355	COG0542	response to heat
NOS7524_RS24370	COG0270	DNA (cytosine-5-)-methyltransferase activity
NOS7524_RS24400	COG2081	HI0933 family
NOS7524_RS24405	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS24410	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS24420	COG0463	Glycosyl transferase, family 2
NOS7524_RS24435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NOS7524_RS24445	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NOS7524_RS24450	COG2048	Heterodisulfide reductase, subunit B
NOS7524_RS24455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NOS7524_RS24460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NOS7524_RS24465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NOS7524_RS24475	COG0840	transmembrane signaling receptor activity
NOS7524_RS24475	COG2203	Gaf domain
NOS7524_RS24480	COG5002	protein histidine kinase activity
NOS7524_RS24485	COG0583	DNA-binding transcription factor activity
NOS7524_RS24490	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
NOS7524_RS24495	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NOS7524_RS24505	COG4451	ribulose bisphosphate carboxylase, small
NOS7524_RS24505	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NOS7524_RS24510	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
NOS7524_RS24515	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
NOS7524_RS24520	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
NOS7524_RS24525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NOS7524_RS24530	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS24585	COG0180	Tryptophanyl-tRNA synthetase
NOS7524_RS24600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NOS7524_RS24600	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NOS7524_RS24610	COG2048	Heterodisulfide reductase, subunit B
NOS7524_RS24695	COG0497	DNA recombination
NOS7524_RS24700	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NOS7524_RS24715	COG0525	valine-tRNA ligase activity
NOS7524_RS24720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NOS7524_RS24725	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NOS7524_RS24745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NOS7524_RS24750	COG1215	transferase activity, transferring glycosyl groups
NOS7524_RS24760	COG0857	belongs to the CobB CobQ family
NOS7524_RS24775	COG1666	GTP binding
NOS7524_RS24780	COG0625	glutathione transferase activity
NOS7524_RS24805	COG1070	Carbohydrate kinase
NOS7524_RS24810	COG2971	BadF BadG BcrA BcrD
NOS7524_RS24815	COG2807	transmembrane transport
NOS7524_RS24825	COG3237	CsbD-like
NOS7524_RS24830	COG4572	Cation transport regulator
NOS7524_RS24835	COG0783	Belongs to the Dps family
NOS7524_RS24855	COG0259	pyridoxamine-phosphate oxidase activity
NOS7524_RS24860	COG0628	permease
NOS7524_RS24875	COG3659	wide pore channel activity
NOS7524_RS24895	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NOS7524_RS24905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NOS7524_RS24905	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
NOS7524_RS24925	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NOS7524_RS24930	COG2197	response regulator
NOS7524_RS24940	COG2226	methyltransferase
NOS7524_RS24945	COG0776	regulation of translation
NOS7524_RS24950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NOS7524_RS24955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NOS7524_RS24970	COG2197	response regulator
NOS7524_RS24980	COG4372	Transposase
NOS7524_RS24985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NOS7524_RS24990	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NOS7524_RS24995	COG0131	Imidazoleglycerol-phosphate dehydratase
NOS7524_RS25000	COG0515	serine threonine protein kinase
NOS7524_RS25000	COG2815	serine threonine protein kinase
NOS7524_RS25005	COG1131	(ABC) transporter
NOS7524_RS25010	COG1596	polysaccharide export
NOS7524_RS25015	COG0330	HflC and HflK could
NOS7524_RS25020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NOS7524_RS25025	COG0149	triose-phosphate isomerase activity
NOS7524_RS25030	COG1160	GTP binding
NOS7524_RS25035	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NOS7524_RS25050	COG2003	Belongs to the UPF0758 family
NOS7524_RS25080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NOS7524_RS25085	COG0577	efflux transmembrane transporter activity
NOS7524_RS25085	COG1136	(ABC) transporter
NOS7524_RS25125	COG1357	PFAM Pentapeptide repeats (8 copies)
NOS7524_RS25125	COG0515	serine threonine protein kinase
NOS7524_RS25135	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NOS7524_RS25140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NOS7524_RS25160	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NOS7524_RS25190	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NOS7524_RS25200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NOS7524_RS25210	COG5001	Diguanylate cyclase
NOS7524_RS25215	COG3000	fatty acid hydroxylase
NOS7524_RS25215	COG0300	oxidoreductase activity
NOS7524_RS25240	COG0584	glycerophosphoryl diester phosphodiesterase
NOS7524_RS25245	COG0312	modulator of DNA gyrase
NOS7524_RS25250	COG0312	modulator of DNA gyrase
NOS7524_RS25315	COG0515	serine threonine protein kinase
NOS7524_RS25325	COG1187	pseudouridine synthase activity
NOS7524_RS25330	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NOS7524_RS25355	COG1215	transferase activity, transferring glycosyl groups
NOS7524_RS25360	COG4968	Prepilin-type N-terminal cleavage methylation domain
NOS7524_RS25380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NOS7524_RS25385	COG0326	Molecular chaperone. Has ATPase activity
NOS7524_RS25390	COG1216	Glycosyl transferase, family 2
NOS7524_RS25395	COG0463	Glycosyl transferase, family 2
NOS7524_RS25400	COG0463	Glycosyl transferase, family 2
NOS7524_RS25400	COG1216	Glycosyl transferase, family 2
NOS7524_RS25405	COG1215	transferase activity, transferring glycosyl groups
NOS7524_RS25410	COG0542	response to heat
NOS7524_RS25415	COG0346	lactoylglutathione lyase activity
NOS7524_RS25420	COG0148	phosphopyruvate hydratase activity
NOS7524_RS25425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NOS7524_RS25430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NOS7524_RS25430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NOS7524_RS25445	COG2205	protein histidine kinase activity
NOS7524_RS25445	COG2202	Pas domain
NOS7524_RS25450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NOS7524_RS25465	COG1253	flavin adenine dinucleotide binding
NOS7524_RS25475	COG2267	carboxylic ester hydrolase activity
NOS7524_RS25485	COG0668	transmembrane transport
NOS7524_RS25490	COG0123	including yeast histone deacetylase and acetoin utilization protein
NOS7524_RS25495	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NOS7524_RS25500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NOS7524_RS25505	COG4942	peptidase
NOS7524_RS25505	COG1388	LysM domain
NOS7524_RS25530	COG0604	alcohol dehydrogenase
NOS7524_RS25530	COG3321	synthase
NOS7524_RS25550	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NOS7524_RS25560	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NOS7524_RS25565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NOS7524_RS25575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NOS7524_RS25580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NOS7524_RS25585	COG1045	serine acetyltransferase
NOS7524_RS25600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NOS7524_RS25605	COG5554	nitrogen fixation
NOS7524_RS25625	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS25655	COG2336	PFAM SpoVT AbrB
NOS7524_RS25660	COG2337	Toxic component of a toxin-antitoxin (TA) module
NOS7524_RS25685	COG0442	prolyl-tRNA aminoacylation
NOS7524_RS25695	COG0640	Transcriptional regulator
NOS7524_RS25700	COG0511	ligase activity, forming carbon-carbon bonds
NOS7524_RS25705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NOS7524_RS25710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NOS7524_RS25720	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NOS7524_RS25725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NOS7524_RS25730	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NOS7524_RS25735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NOS7524_RS25740	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NOS7524_RS25745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NOS7524_RS25750	COG0697	spore germination
NOS7524_RS25765	COG3852	Histidine kinase
NOS7524_RS25790	COG1404	Belongs to the peptidase S8 family
NOS7524_RS25800	COG0351	phosphomethylpyrimidine kinase
NOS7524_RS25815	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NOS7524_RS25825	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NOS7524_RS25830	COG3977	Valine--pyruvate aminotransferase
NOS7524_RS25835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NOS7524_RS25870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NOS7524_RS25875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NOS7524_RS25880	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NOS7524_RS25885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NOS7524_RS25890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NOS7524_RS25895	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NOS7524_RS25900	COG0356	it plays a direct role in the translocation of protons across the membrane
NOS7524_RS25910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NOS7524_RS25945	COG4245	von Willebrand factor, type A
NOS7524_RS25975	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NOS7524_RS25975	COG0237	dephospho-CoA kinase activity
NOS7524_RS26000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NOS7524_RS26000	COG4191	Histidine kinase
NOS7524_RS26005	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS26010	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS26035	COG0772	Belongs to the SEDS family
NOS7524_RS26045	COG0601	transmembrane transport
NOS7524_RS26055	COG0328	RNA-DNA hybrid ribonuclease activity
NOS7524_RS26075	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NOS7524_RS26080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NOS7524_RS26095	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
NOS7524_RS26115	COG0539	negative regulation of cytoplasmic translation
NOS7524_RS26140	COG0429	hydrolase of the alpha beta-hydrolase fold
NOS7524_RS26145	COG0745	RESPONSE REGULATOR receiver
NOS7524_RS26150	COG0644	oxidoreductase
NOS7524_RS26155	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NOS7524_RS26175	COG2091	lysine biosynthetic process via aminoadipic acid
NOS7524_RS26180	COG0300	oxidoreductase activity
NOS7524_RS26185	COG3320	Male sterility
NOS7524_RS26185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NOS7524_RS26190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NOS7524_RS26190	COG2070	2-Nitropropane dioxygenase
NOS7524_RS26195	COG4221	oxidoreductase activity
NOS7524_RS26195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NOS7524_RS26195	COG0300	oxidoreductase activity
NOS7524_RS26195	COG3321	synthase
NOS7524_RS26205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NOS7524_RS26205	COG4221	oxidoreductase activity
NOS7524_RS26205	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS26205	COG3321	synthase
NOS7524_RS26210	COG3321	synthase
NOS7524_RS26210	COG0604	alcohol dehydrogenase
NOS7524_RS26220	COG1475	DNA binding
NOS7524_RS26245	COG1216	Glycosyl transferase, family 2
NOS7524_RS26290	COG0501	Belongs to the peptidase M48B family
NOS7524_RS26300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NOS7524_RS26325	COG0768	penicillin binding
NOS7524_RS26345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NOS7524_RS26360	COG0748	coenzyme F420 binding
NOS7524_RS26385	COG2010	Cytochrome c
NOS7524_RS26395	COG0395	ABC-type sugar transport system, permease component
NOS7524_RS26405	COG4771	TonB-dependent receptor
NOS7524_RS26405	COG1629	transport
NOS7524_RS26420	COG1175	transmembrane transport
NOS7524_RS26425	COG1028	Short-chain dehydrogenase reductase Sdr
NOS7524_RS26435	COG3228	Belongs to the MtfA family
NOS7524_RS26440	COG3829	transcription factor binding
NOS7524_RS26450	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NOS7524_RS26460	COG0534	Mate efflux family protein
NOS7524_RS26465	COG1773	rubredoxin
NOS7524_RS26465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NOS7524_RS26470	COG1902	pentaerythritol trinitrate reductase activity
NOS7524_RS26485	COG1741	Belongs to the pirin family
NOS7524_RS26495	COG0667	Aldo Keto reductase
NOS7524_RS26520	COG2022	thiamine diphosphate biosynthetic process
NOS7524_RS26520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NOS7524_RS26525	COG2267	carboxylic ester hydrolase activity
NOS7524_RS26530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NOS7524_RS26535	COG0170	dolichyl monophosphate biosynthetic process
NOS7524_RS26580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NOS7524_RS26585	COG0528	UMP kinase activity
NOS7524_RS26590	COG0233	cytoplasmic translational termination
NOS7524_RS26595	COG0492	ferredoxin-NADP+ reductase activity
NOS7524_RS26600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NOS7524_RS26620	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
NOS7524_RS26625	COG3706	GGDEF domain
NOS7524_RS26625	COG2203	Gaf domain
NOS7524_RS26625	COG5001	Diguanylate cyclase
NOS7524_RS26625	COG4251	negative regulation of phosphorylation
NOS7524_RS26640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NOS7524_RS26645	COG5002	protein histidine kinase activity
NOS7524_RS26650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NOS7524_RS26655	COG3150	esterase
NOS7524_RS26660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NOS7524_RS26720	COG1132	(ABC) transporter
NOS7524_RS26735	COG0488	(ABC) transporter
NOS7524_RS26750	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NOS7524_RS26785	COG2815	serine threonine protein kinase
NOS7524_RS26785	COG0515	serine threonine protein kinase
NOS7524_RS26810	COG2217	Heavy metal translocating P-type atpase
NOS7524_RS26815	COG1981	membrane
NOS7524_RS26825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NOS7524_RS26840	COG0300	oxidoreductase activity
NOS7524_RS26850	COG1982	Orn Lys Arg decarboxylase major
NOS7524_RS26870	COG0012	GTP binding
NOS7524_RS26880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NOS7524_RS26910	COG1053	succinate dehydrogenase
NOS7524_RS26920	COG2885	chlorophyll binding
NOS7524_RS26925	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOS7524_RS26935	COG3659	wide pore channel activity
NOS7524_RS26970	COG0725	ABC transporter, periplasmic molybdate-binding protein
NOS7524_RS27025	COG1410	methionine synthase
NOS7524_RS27025	COG0646	methionine synthase
NOS7524_RS27045	COG3409	Peptidoglycan-binding domain 1 protein
NOS7524_RS27045	COG0793	Belongs to the peptidase S41A family
NOS7524_RS27050	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS27065	COG0358	DNA primase activity
NOS7524_RS27070	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NOS7524_RS27075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NOS7524_RS27090	COG2095	MarC family integral membrane protein
NOS7524_RS27110	COG2217	Heavy metal translocating P-type atpase
NOS7524_RS27125	COG0242	peptide deformylase activity
NOS7524_RS27130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NOS7524_RS27340	COG0438	transferase activity, transferring glycosyl groups
NOS7524_RS27705	COG2205	protein histidine kinase activity
NOS7524_RS27705	COG0784	Response regulator, receiver
NOS7524_RS27725	COG4251	negative regulation of phosphorylation
NOS7524_RS27725	COG2203	Gaf domain
NOS7524_RS27725	COG3706	GGDEF domain
NOS7524_RS27725	COG5001	Diguanylate cyclase
NOS7524_RS27745	COG2205	protein histidine kinase activity
NOS7524_RS27745	COG0784	Response regulator, receiver
NOS7524_RS27775	COG1216	Glycosyl transferase, family 2
NOS7524_RS27815	COG5002	protein histidine kinase activity
NOS7524_RS27820	COG5001	Diguanylate cyclase
NOS7524_RS27820	COG4251	negative regulation of phosphorylation
NOS7524_RS27820	COG2203	Gaf domain
NOS7524_RS27820	COG3706	GGDEF domain
NOS7524_RS27845	COG2319	Wd-40 repeat
NOS7524_RS27845	COG1672	PFAM Archaeal ATPase
NOS7524_RS27855	COG0739	heme binding
NOS7524_RS27870	COG2319	Wd-40 repeat
NOS7524_RS27870	COG3903	Transcriptional regulator
NOS7524_RS27890	COG5002	protein histidine kinase activity
NOS7524_RS27900	COG0515	serine threonine protein kinase
NOS7524_RS27930	COG2202	Pas domain
NOS7524_RS27930	COG2205	protein histidine kinase activity
NOS7524_RS27940	COG0515	serine threonine protein kinase