locus-tag	class	description
PP1Y_RS00240	COG0045	succinate-CoA ligase (ADP-forming) activity
PP1Y_RS00300	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PP1Y_RS00400	COG0113	porphobilinogen synthase activity
PP1Y_RS00495	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PP1Y_RS00655	COG0495	leucyl-tRNA aminoacylation
PP1Y_RS01155	COG0445	tRNA wobble uridine modification
PP1Y_RS01875	COG0348	domain, Protein
PP1Y_RS01940	COG0450	alkyl hydroperoxide reductase
PP1Y_RS01960	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PP1Y_RS02265	COG3451	type IV secretory pathway VirB4
PP1Y_RS02910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PP1Y_RS02910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PP1Y_RS03200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PP1Y_RS04340	COG3746	phosphate-selective porin O and P
PP1Y_RS04885	COG0494	nUDIX hydrolase
PP1Y_RS05130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PP1Y_RS05140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PP1Y_RS05155	COG0582	viral genome integration into host DNA
PP1Y_RS05605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PP1Y_RS05605	COG3153	acetyltransferase
PP1Y_RS05675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PP1Y_RS05960	COG2814	Major facilitator Superfamily
PP1Y_RS06060	COG4774	siderophore transport
PP1Y_RS06110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PP1Y_RS06135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PP1Y_RS06140	COG1981	membrane
PP1Y_RS06145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PP1Y_RS06150	COG0861	Integral membrane protein TerC family
PP1Y_RS06160	COG0069	glutamate synthase activity
PP1Y_RS06175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PP1Y_RS06180	COG0445	tRNA wobble uridine modification
PP1Y_RS06185	COG0357	Ribosomal RNA small subunit methyltransferase G
PP1Y_RS06205	COG1956	GAF domain-containing protein
PP1Y_RS06220	COG0009	L-threonylcarbamoyladenylate synthase
PP1Y_RS06230	COG1329	Transcriptional regulator
PP1Y_RS06235	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PP1Y_RS06250	COG0739	heme binding
PP1Y_RS06255	COG0113	porphobilinogen synthase activity
PP1Y_RS06270	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PP1Y_RS06275	COG1872	DUF167
PP1Y_RS06300	COG3321	synthase
PP1Y_RS06300	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS06300	COG0604	alcohol dehydrogenase
PP1Y_RS06315	COG0318	PFAM AMP-dependent synthetase and ligase
PP1Y_RS06325	COG0739	heme binding
PP1Y_RS06330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PP1Y_RS06335	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PP1Y_RS06340	COG0799	negative regulation of ribosome biogenesis
PP1Y_RS06345	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PP1Y_RS06355	COG1218	3'(2'),5'-bisphosphate nucleotidase
PP1Y_RS06360	COG0045	succinate-CoA ligase (ADP-forming) activity
PP1Y_RS06365	COG2086	electron transfer activity
PP1Y_RS06380	COG2733	membrane
PP1Y_RS06405	COG0482	sulfurtransferase activity
PP1Y_RS06425	COG0259	pyridoxamine-phosphate oxidase activity
PP1Y_RS06430	COG0484	heat shock protein binding
PP1Y_RS06435	COG1295	ribonuclease BN
PP1Y_RS06440	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PP1Y_RS06450	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PP1Y_RS06460	COG0793	Belongs to the peptidase S41A family
PP1Y_RS06470	COG2885	chlorophyll binding
PP1Y_RS06480	COG1253	flavin adenine dinucleotide binding
PP1Y_RS06490	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PP1Y_RS06495	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PP1Y_RS06500	COG0196	riboflavin kinase activity
PP1Y_RS06510	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PP1Y_RS06520	COG0588	phosphoglycerate mutase activity
PP1Y_RS06545	COG1196	nuclear chromosome segregation
PP1Y_RS06545	COG0741	lytic transglycosylase activity
PP1Y_RS06545	COG0739	heme binding
PP1Y_RS06555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PP1Y_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS06585	COG0495	leucyl-tRNA aminoacylation
PP1Y_RS06620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PP1Y_RS06630	COG0070	glutamate synthase
PP1Y_RS06630	COG0067	glutamate synthase
PP1Y_RS06630	COG0069	glutamate synthase activity
PP1Y_RS06640	COG0297	glycogen (starch) synthase activity
PP1Y_RS06665	COG1346	cytolysis
PP1Y_RS06670	COG1380	Effector of murein hydrolase LrgA
PP1Y_RS06675	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PP1Y_RS06680	COG0281	malic enzyme
PP1Y_RS06680	COG0280	phosphate acetyltransferase
PP1Y_RS06685	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PP1Y_RS06700	COG1250	3-hydroxyacyl-CoA dehydrogenase
PP1Y_RS06715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PP1Y_RS06765	COG1213	nucleotidyl transferase
PP1Y_RS06770	COG2244	polysaccharide biosynthetic process
PP1Y_RS06775	COG1473	amidohydrolase
PP1Y_RS06805	COG0501	Belongs to the peptidase M48B family
PP1Y_RS06810	COG0308	aminopeptidase N
PP1Y_RS06815	COG1496	oxidoreductase activity
PP1Y_RS06820	COG0723	plastoquinol--plastocyanin reductase activity
PP1Y_RS06835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PP1Y_RS06850	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS06855	COG0583	DNA-binding transcription factor activity
PP1Y_RS06910	COG3119	arylsulfatase activity
PP1Y_RS06915	COG3119	arylsulfatase activity
PP1Y_RS06920	COG3119	arylsulfatase activity
PP1Y_RS06925	COG3119	arylsulfatase activity
PP1Y_RS06935	COG2814	Major facilitator Superfamily
PP1Y_RS06970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PP1Y_RS07040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PP1Y_RS07055	COG1294	oxidase, subunit
PP1Y_RS07060	COG1271	oxidase subunit
PP1Y_RS07080	COG2391	methyltransferase activity
PP1Y_RS07095	COG0450	alkyl hydroperoxide reductase
PP1Y_RS07105	COG0739	heme binding
PP1Y_RS07105	COG0741	lytic transglycosylase activity
PP1Y_RS07105	COG1196	nuclear chromosome segregation
PP1Y_RS07110	COG2833	Protein of unknown function (DUF455)
PP1Y_RS07115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PP1Y_RS07120	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PP1Y_RS07130	COG2957	Belongs to the agmatine deiminase family
PP1Y_RS07135	COG0071	Belongs to the small heat shock protein (HSP20) family
PP1Y_RS07145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PP1Y_RS07160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PP1Y_RS07170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PP1Y_RS07175	COG4152	abc transporter atp-binding protein
PP1Y_RS07185	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PP1Y_RS07205	COG0776	regulation of translation
PP1Y_RS07210	COG3104	oligopeptide transport
PP1Y_RS07215	COG1228	amidohydrolase
PP1Y_RS07225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PP1Y_RS07245	COG0138	bifunctional purine biosynthesis protein purh
PP1Y_RS07255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PP1Y_RS07265	COG0351	phosphomethylpyrimidine kinase
PP1Y_RS07300	COG0312	modulator of DNA gyrase
PP1Y_RS07310	COG1131	(ABC) transporter
PP1Y_RS07325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PP1Y_RS07325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PP1Y_RS07355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PP1Y_RS07365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PP1Y_RS07375	COG0762	integral membrane protein
PP1Y_RS07380	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PP1Y_RS07390	COG2095	MarC family integral membrane protein
PP1Y_RS07420	COG5489	Protein of unknown function (DUF736)
PP1Y_RS07455	COG4959	Type IV secretory pathway protease TraF
PP1Y_RS07465	COG0741	lytic transglycosylase activity
PP1Y_RS07485	COG1959	2 iron, 2 sulfur cluster binding
PP1Y_RS07490	COG2346	COG2346, Truncated hemoglobins
PP1Y_RS07505	COG1017	nitric oxide dioxygenase activity
PP1Y_RS07505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PP1Y_RS07525	COG4962	Type ii secretion system protein e
PP1Y_RS07540	COG3451	type IV secretory pathway VirB4
PP1Y_RS07570	COG2948	multi-organism process
PP1Y_RS07580	COG0583	DNA-binding transcription factor activity
PP1Y_RS07595	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PP1Y_RS07600	COG0732	type I restriction modification DNA specificity domain
PP1Y_RS07610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PP1Y_RS07630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PP1Y_RS07640	COG0420	3'-5' exonuclease activity
PP1Y_RS07655	COG1475	DNA binding
PP1Y_RS07675	COG2925	Exonuclease
PP1Y_RS07680	COG2856	Zn peptidase
PP1Y_RS07715	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS07720	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS07725	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS07755	COG2072	flavoprotein involved in K transport
PP1Y_RS07760	COG5654	RES domain protein
PP1Y_RS07790	COG0464	growth
PP1Y_RS07800	COG0582	viral genome integration into host DNA
PP1Y_RS07825	COG3750	Belongs to the UPF0335 family
PP1Y_RS08010	COG4695	Portal protein
PP1Y_RS08035	COG0582	viral genome integration into host DNA
PP1Y_RS08050	COG1024	Enoyl-CoA hydratase
PP1Y_RS08060	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PP1Y_RS08070	COG0077	Prephenate dehydratase
PP1Y_RS08085	COG0714	Associated with various cellular activities
PP1Y_RS08105	COG0454	-acetyltransferase
PP1Y_RS08120	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PP1Y_RS08125	COG3577	Aspartyl protease
PP1Y_RS08130	COG2814	Major facilitator Superfamily
PP1Y_RS08135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PP1Y_RS08140	COG0085	RNA polymerase activity
PP1Y_RS08160	COG3655	Transcriptional regulator
PP1Y_RS08165	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PP1Y_RS08170	COG0222	ribosome binding
PP1Y_RS08180	COG2954	triphosphatase activity
PP1Y_RS08195	COG0534	Mate efflux family protein
PP1Y_RS08200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PP1Y_RS08205	COG0459	protein refolding
PP1Y_RS08220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PP1Y_RS08220	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PP1Y_RS08230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PP1Y_RS08240	COG0583	DNA-binding transcription factor activity
PP1Y_RS08255	COG0386	Belongs to the glutathione peroxidase family
PP1Y_RS08270	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PP1Y_RS08275	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PP1Y_RS08285	COG2890	protein-(glutamine-N5) methyltransferase activity
PP1Y_RS08290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PP1Y_RS08295	COG0124	histidyl-tRNA synthetase
PP1Y_RS08305	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PP1Y_RS08330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PP1Y_RS08365	COG2130	NADP-dependent
PP1Y_RS08380	COG0114	fumarate hydratase activity
PP1Y_RS08385	COG1741	Belongs to the pirin family
PP1Y_RS08390	COG1741	Belongs to the pirin family
PP1Y_RS08415	COG0432	Pfam Uncharacterised protein family UPF0047
PP1Y_RS08425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PP1Y_RS08430	COG1760	l-serine dehydratase
PP1Y_RS08435	COG1115	amino acid carrier protein
PP1Y_RS08440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PP1Y_RS08445	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PP1Y_RS08450	COG0717	Belongs to the dCTP deaminase family
PP1Y_RS08455	COG0456	acetyltransferase
PP1Y_RS08460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PP1Y_RS08465	COG1917	Cupin 2, conserved barrel domain protein
PP1Y_RS08470	COG5285	phytanoyl-CoA dioxygenase
PP1Y_RS08475	COG0527	aspartate kinase activity
PP1Y_RS08490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PP1Y_RS08495	COG0165	Argininosuccinate lyase
PP1Y_RS08505	COG0019	diaminopimelate decarboxylase activity
PP1Y_RS08510	COG1648	precorrin-2 dehydrogenase activity
PP1Y_RS08510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PP1Y_RS08525	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PP1Y_RS08535	COG0681	Belongs to the peptidase S26 family
PP1Y_RS08540	COG0736	holo-[acyl-carrier-protein] synthase activity
PP1Y_RS08545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PP1Y_RS08550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PP1Y_RS08560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PP1Y_RS08565	COG0109	protoheme IX farnesyltransferase activity
PP1Y_RS08570	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PP1Y_RS08610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PP1Y_RS08620	COG0314	molybdopterin synthase activity
PP1Y_RS08635	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PP1Y_RS08640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PP1Y_RS08655	COG0354	folic acid binding
PP1Y_RS08660	COG0583	DNA-binding transcription factor activity
PP1Y_RS08680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PP1Y_RS08700	COG1012	belongs to the aldehyde dehydrogenase family
PP1Y_RS08705	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PP1Y_RS08715	COG0438	transferase activity, transferring glycosyl groups
PP1Y_RS08740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PP1Y_RS08760	COG0789	Transcriptional regulator
PP1Y_RS08765	COG1196	nuclear chromosome segregation
PP1Y_RS08795	COG2816	NAD+ diphosphatase activity
PP1Y_RS08805	COG2239	Acts as a magnesium transporter
PP1Y_RS08815	COG0583	DNA-binding transcription factor activity
PP1Y_RS08820	COG1253	flavin adenine dinucleotide binding
PP1Y_RS08825	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PP1Y_RS08840	COG2267	carboxylic ester hydrolase activity
PP1Y_RS08845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PP1Y_RS08850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PP1Y_RS08865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PP1Y_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS08875	COG1063	alcohol dehydrogenase
PP1Y_RS08895	COG3265	gluconokinase activity
PP1Y_RS08900	COG2814	Major facilitator Superfamily
PP1Y_RS08915	COG0018	arginyl-trna synthetase
PP1Y_RS08925	COG1472	Belongs to the glycosyl hydrolase 3 family
PP1Y_RS08930	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PP1Y_RS08935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PP1Y_RS08940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PP1Y_RS08945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PP1Y_RS08950	COG0805	protein transport
PP1Y_RS08955	COG0402	S-adenosylhomocysteine deaminase activity
PP1Y_RS08960	COG2084	Dehydrogenase
PP1Y_RS08965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PP1Y_RS08975	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PP1Y_RS08995	COG0174	glutamine synthetase
PP1Y_RS09000	COG0347	Belongs to the P(II) protein family
PP1Y_RS09015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PP1Y_RS09025	COG0024	Methionine aminopeptidase
PP1Y_RS09035	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PP1Y_RS09040	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PP1Y_RS09045	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PP1Y_RS09045	COG4106	trans-aconitate 2-methyltransferase activity
PP1Y_RS09055	COG0156	8-amino-7-oxononanoate synthase activity
PP1Y_RS09075	COG1012	belongs to the aldehyde dehydrogenase family
PP1Y_RS09090	COG5002	protein histidine kinase activity
PP1Y_RS09105	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PP1Y_RS09145	COG3474	cytochrome
PP1Y_RS09155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PP1Y_RS09170	COG2884	Cell division ATP-binding protein ftsE
PP1Y_RS09195	COG0287	Prephenate dehydrogenase
PP1Y_RS09200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PP1Y_RS09205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PP1Y_RS09210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PP1Y_RS09210	COG2813	Specifically methylates the guanine in position
PP1Y_RS09215	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PP1Y_RS09225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PP1Y_RS09245	COG1426	Protein conserved in bacteria
PP1Y_RS09255	COG0037	tRNA processing
PP1Y_RS09265	COG1309	transcriptional regulator
PP1Y_RS09270	COG4771	TonB-dependent receptor
PP1Y_RS09275	COG2945	thiolester hydrolase activity
PP1Y_RS09275	COG0596	Alpha beta hydrolase
PP1Y_RS09280	COG2814	Major facilitator Superfamily
PP1Y_RS09290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PP1Y_RS09300	COG4566	intracellular signal transduction
PP1Y_RS09320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PP1Y_RS09330	COG0438	transferase activity, transferring glycosyl groups
PP1Y_RS09345	COG4771	TonB-dependent receptor
PP1Y_RS09360	COG4181	ATPase activity
PP1Y_RS09365	COG2755	lipolytic protein G-D-S-L family
PP1Y_RS09370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PP1Y_RS09410	COG4235	cytochrome complex assembly
PP1Y_RS09415	COG0492	ferredoxin-NADP+ reductase activity
PP1Y_RS09430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PP1Y_RS09480	COG2346	COG2346, Truncated hemoglobins
PP1Y_RS09495	COG0823	Involved in the tonB-independent uptake of proteins
PP1Y_RS09495	COG4946	Tricorn protease homolog
PP1Y_RS09495	COG1506	peptidase
PP1Y_RS09505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PP1Y_RS09520	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PP1Y_RS09525	COG2081	HI0933 family
PP1Y_RS09530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PP1Y_RS09535	COG1609	Transcriptional regulator
PP1Y_RS09540	COG2211	Major facilitator Superfamily
PP1Y_RS09545	COG2902	Dehydrogenase
PP1Y_RS09555	COG3186	Phenylalanine-4-hydroxylase
PP1Y_RS09565	COG0346	lactoylglutathione lyase activity
PP1Y_RS09570	COG0625	glutathione transferase activity
PP1Y_RS09575	COG5001	Diguanylate cyclase
PP1Y_RS09585	COG3724	N-succinylarginine dihydrolase activity
PP1Y_RS09600	COG1012	belongs to the aldehyde dehydrogenase family
PP1Y_RS09615	COG0800	Aldolase
PP1Y_RS09620	COG0837	glucose binding
PP1Y_RS09625	COG0129	dihydroxy-acid dehydratase activity
PP1Y_RS09630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PP1Y_RS09635	COG5002	protein histidine kinase activity
PP1Y_RS09640	COG3746	phosphate-selective porin O and P
PP1Y_RS09645	COG3746	phosphate-selective porin O and P
PP1Y_RS09655	COG0573	inorganic phosphate transmembrane transporter activity
PP1Y_RS09665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PP1Y_RS09670	COG0704	Plays a role in the regulation of phosphate uptake
PP1Y_RS09675	COG0745	RESPONSE REGULATOR receiver
PP1Y_RS09680	COG0438	transferase activity, transferring glycosyl groups
PP1Y_RS09690	COG0745	RESPONSE REGULATOR receiver
PP1Y_RS09695	COG2119	membrane
PP1Y_RS09725	COG3451	type IV secretory pathway VirB4
PP1Y_RS09740	COG2948	multi-organism process
PP1Y_RS09745	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
PP1Y_RS09750	COG0248	Ppx GppA phosphatase
PP1Y_RS09755	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PP1Y_RS09785	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PP1Y_RS09790	COG4133	protoheme IX ABC transporter activity
PP1Y_RS09795	COG2154	pterin-4-alpha-carbinolamine dehydratase
PP1Y_RS09805	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PP1Y_RS09815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PP1Y_RS09830	COG2001	Belongs to the MraZ family
PP1Y_RS09835	COG0275	rRNA processing
PP1Y_RS09850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PP1Y_RS09855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PP1Y_RS09860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PP1Y_RS09865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PP1Y_RS09875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PP1Y_RS09880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PP1Y_RS09890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PP1Y_RS09895	COG1181	Belongs to the D-alanine--D-alanine ligase family
PP1Y_RS09900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PP1Y_RS09905	COG0849	cell division
PP1Y_RS09925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PP1Y_RS09930	COG0670	Belongs to the BI1 family
PP1Y_RS09945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PP1Y_RS09955	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PP1Y_RS09960	COG0702	epimerase
PP1Y_RS09965	COG0840	transmembrane signaling receptor activity
PP1Y_RS09980	COG2719	SpoVR family
PP1Y_RS09985	COG2718	Belongs to the UPF0229 family
PP1Y_RS09990	COG2766	serine protein kinase
PP1Y_RS09995	COG0840	transmembrane signaling receptor activity
PP1Y_RS10005	COG0489	protein tyrosine kinase activity
PP1Y_RS10005	COG3206	protein involved in exopolysaccharide biosynthesis
PP1Y_RS10015	COG5039	Polysaccharide pyruvyl transferase
PP1Y_RS10020	COG2244	polysaccharide biosynthetic process
PP1Y_RS10035	COG1215	transferase activity, transferring glycosyl groups
PP1Y_RS10045	COG1045	serine acetyltransferase
PP1Y_RS10060	COG0438	transferase activity, transferring glycosyl groups
PP1Y_RS10075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PP1Y_RS10080	COG0438	transferase activity, transferring glycosyl groups
PP1Y_RS10085	COG1215	transferase activity, transferring glycosyl groups
PP1Y_RS10100	COG1132	(ABC) transporter
PP1Y_RS10105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PP1Y_RS10110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PP1Y_RS10135	COG0463	Glycosyl transferase, family 2
PP1Y_RS10210	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PP1Y_RS10215	COG3387	PFAM Glycoside hydrolase 15-related
PP1Y_RS10225	COG0668	transmembrane transport
PP1Y_RS10230	COG0662	Cupin 2, conserved barrel domain protein
PP1Y_RS10230	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PP1Y_RS10245	COG0783	Belongs to the Dps family
PP1Y_RS10250	COG0363	glucosamine-6-phosphate deaminase activity
PP1Y_RS10255	COG0494	nUDIX hydrolase
PP1Y_RS10295	COG1247	-acetyltransferase
PP1Y_RS10305	COG1573	uracil-dna glycosylase
PP1Y_RS10325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PP1Y_RS10365	COG1764	response to oxidative stress
PP1Y_RS10385	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PP1Y_RS10410	COG2171	N-acyltransferase activity
PP1Y_RS10415	COG0194	GDP metabolic process
PP1Y_RS10430	COG0131	Imidazoleglycerol-phosphate dehydratase
PP1Y_RS10440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PP1Y_RS10445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PP1Y_RS10450	COG0107	imidazoleglycerol-phosphate synthase activity
PP1Y_RS10455	COG0140	phosphoribosyl-ATP diphosphatase activity
PP1Y_RS10465	COG0824	Thioesterase
PP1Y_RS10485	COG0823	Involved in the tonB-independent uptake of proteins
PP1Y_RS10490	COG2885	chlorophyll binding
PP1Y_RS10500	COG0484	heat shock protein binding
PP1Y_RS10505	COG0471	metal ion transport
PP1Y_RS10510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PP1Y_RS10520	COG0408	coproporphyrinogen oxidase activity
PP1Y_RS10535	COG0477	Major facilitator Superfamily
PP1Y_RS10575	COG0582	viral genome integration into host DNA
PP1Y_RS10580	COG4584	PFAM Integrase catalytic
PP1Y_RS10585	COG1484	DNA-dependent DNA replication
PP1Y_RS10600	COG0746	molybdenum cofactor guanylyltransferase activity
PP1Y_RS10610	COG0436	Aminotransferase
PP1Y_RS10615	COG3243	poly(R)-hydroxyalkanoic acid synthase
PP1Y_RS10660	COG0321	lipoyl(octanoyl) transferase activity
PP1Y_RS10680	COG2080	2 iron, 2 sulfur cluster binding
PP1Y_RS10690	COG1678	Uncharacterized ACR, COG1678
PP1Y_RS10715	COG1132	(ABC) transporter
PP1Y_RS10725	COG1968	undecaprenyl-diphosphatase activity
PP1Y_RS10730	COG2326	polyphosphate kinase activity
PP1Y_RS10735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PP1Y_RS10745	COG0708	Exodeoxyribonuclease III
PP1Y_RS10775	COG0861	Integral membrane protein TerC family
PP1Y_RS10815	COG2259	Doxx family
PP1Y_RS10830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PP1Y_RS10840	COG3920	Histidine kinase
PP1Y_RS10845	COG0784	Response regulator, receiver
PP1Y_RS10855	COG0784	Response regulator, receiver
PP1Y_RS10875	COG4251	negative regulation of phosphorylation
PP1Y_RS10910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PP1Y_RS10925	COG1024	Enoyl-CoA hydratase
PP1Y_RS10930	COG0583	DNA-binding transcription factor activity
PP1Y_RS10935	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PP1Y_RS10945	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PP1Y_RS10950	COG2116	formate transmembrane transporter activity
PP1Y_RS10955	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PP1Y_RS10980	COG0367	asparagine synthase
PP1Y_RS10985	COG0540	Belongs to the ATCase OTCase family
PP1Y_RS11000	COG1522	sequence-specific DNA binding
PP1Y_RS11015	COG2814	Major facilitator Superfamily
PP1Y_RS11025	COG0175	sulfate reduction
PP1Y_RS11035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PP1Y_RS11065	COG0626	cystathionine gamma-synthase activity
PP1Y_RS11075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PP1Y_RS11085	COG3153	acetyltransferase
PP1Y_RS11085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PP1Y_RS11100	COG2610	gluconate transmembrane transporter activity
PP1Y_RS11120	COG0366	Alpha amylase catalytic
PP1Y_RS11125	COG0058	SHG alpha-glucan phosphorylase activity
PP1Y_RS11130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PP1Y_RS11135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PP1Y_RS11140	COG0297	glycogen (starch) synthase activity
PP1Y_RS11155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PP1Y_RS11155	COG1116	anion transmembrane transporter activity
PP1Y_RS11160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PP1Y_RS11165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PP1Y_RS11170	COG1116	anion transmembrane transporter activity
PP1Y_RS11185	COG2815	serine threonine protein kinase
PP1Y_RS11185	COG0515	serine threonine protein kinase
PP1Y_RS11190	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
PP1Y_RS11195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PP1Y_RS11200	COG2146	nitrite reductase [NAD(P)H] activity
PP1Y_RS11205	COG0243	molybdopterin cofactor binding
PP1Y_RS11210	COG1648	precorrin-2 dehydrogenase activity
PP1Y_RS11210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PP1Y_RS11220	COG1595	DNA-templated transcription, initiation
PP1Y_RS11240	COG0506	proline dehydrogenase activity
PP1Y_RS11255	COG1216	Glycosyl transferase, family 2
PP1Y_RS11260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PP1Y_RS11265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PP1Y_RS11290	COG2244	polysaccharide biosynthetic process
PP1Y_RS11320	COG1442	glycosyl transferase family 8
PP1Y_RS11320	COG1216	Glycosyl transferase, family 2
PP1Y_RS11330	COG0438	transferase activity, transferring glycosyl groups
PP1Y_RS11335	COG0489	protein tyrosine kinase activity
PP1Y_RS11335	COG3206	protein involved in exopolysaccharide biosynthesis
PP1Y_RS11375	COG1414	Transcriptional regulator
PP1Y_RS11390	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PP1Y_RS11395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PP1Y_RS11400	COG2188	Transcriptional regulator
PP1Y_RS11410	COG1335	isochorismatase
PP1Y_RS11430	COG2814	Major facilitator Superfamily
PP1Y_RS11435	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS11445	COG4774	siderophore transport
PP1Y_RS11465	COG0402	S-adenosylhomocysteine deaminase activity
PP1Y_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS11475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PP1Y_RS11505	COG4774	siderophore transport
PP1Y_RS11535	COG1335	isochorismatase
PP1Y_RS11550	COG1335	isochorismatase
PP1Y_RS11555	COG0300	oxidoreductase activity
PP1Y_RS11560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PP1Y_RS11565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PP1Y_RS11570	COG1335	isochorismatase
PP1Y_RS11575	COG2271	Major facilitator Superfamily
PP1Y_RS11590	COG2175	clavaminate synthase activity
PP1Y_RS11600	COG3384	dioxygenase
PP1Y_RS11620	COG4771	TonB-dependent receptor
PP1Y_RS11625	COG0667	Aldo Keto reductase
PP1Y_RS11630	COG0385	Bile acid
PP1Y_RS11635	COG1477	protein flavinylation
PP1Y_RS11660	COG4774	siderophore transport
PP1Y_RS11675	COG5001	Diguanylate cyclase
PP1Y_RS11675	COG3300	MHYT domain
PP1Y_RS11680	COG0318	PFAM AMP-dependent synthetase and ligase
PP1Y_RS11695	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PP1Y_RS11700	COG0271	Belongs to the BolA IbaG family
PP1Y_RS11710	COG0066	3-isopropylmalate dehydratase activity
PP1Y_RS11715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PP1Y_RS11735	COG2166	iron-sulfur cluster assembly
PP1Y_RS11765	COG1842	Phage shock protein A
PP1Y_RS11775	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PP1Y_RS11800	COG0779	Required for maturation of 30S ribosomal subunits
PP1Y_RS11815	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PP1Y_RS11820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PP1Y_RS11830	COG1435	thymidine kinase activity
PP1Y_RS11840	COG1994	Peptidase M50
PP1Y_RS11850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PP1Y_RS11855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PP1Y_RS11860	COG1185	polyribonucleotide nucleotidyltransferase activity
PP1Y_RS11865	COG2814	Major facilitator Superfamily
PP1Y_RS11880	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS11890	COG4771	TonB-dependent receptor
PP1Y_RS11900	COG0702	epimerase
PP1Y_RS11925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PP1Y_RS11935	COG4771	TonB-dependent receptor
PP1Y_RS11960	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS11975	COG3246	L-lysine catabolic process to acetate
PP1Y_RS12000	COG0625	glutathione transferase activity
PP1Y_RS12035	COG2814	Major facilitator Superfamily
PP1Y_RS12040	COG1960	acyl-CoA dehydrogenase activity
PP1Y_RS12090	COG1609	Transcriptional regulator
PP1Y_RS12100	COG2197	response regulator
PP1Y_RS12110	COG1049	propionate catabolic process, 2-methylcitrate cycle
PP1Y_RS12120	COG2814	Major facilitator Superfamily
PP1Y_RS12135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PP1Y_RS12155	COG1448	Aminotransferase
PP1Y_RS12170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PP1Y_RS12170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PP1Y_RS12185	COG2983	Belongs to the UPF0260 family
PP1Y_RS12190	COG1999	signal sequence binding
PP1Y_RS12215	COG0629	single-stranded DNA binding
PP1Y_RS12245	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PP1Y_RS12250	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PP1Y_RS12260	COG0659	secondary active sulfate transmembrane transporter activity
PP1Y_RS12265	COG5265	(ABC) transporter
PP1Y_RS12285	COG1215	transferase activity, transferring glycosyl groups
PP1Y_RS12360	COG4771	TonB-dependent receptor
PP1Y_RS12365	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PP1Y_RS12365	COG1082	Xylose isomerase domain protein TIM barrel
PP1Y_RS12370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PP1Y_RS12380	COG1309	transcriptional regulator
PP1Y_RS12415	COG4771	TonB-dependent receptor
PP1Y_RS12425	COG0402	S-adenosylhomocysteine deaminase activity
PP1Y_RS12435	COG0318	PFAM AMP-dependent synthetase and ligase
PP1Y_RS12450	COG1024	Enoyl-CoA hydratase
PP1Y_RS12450	COG1250	3-hydroxyacyl-CoA dehydrogenase
PP1Y_RS12455	COG0318	PFAM AMP-dependent synthetase and ligase
PP1Y_RS12460	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS12470	COG1024	Enoyl-CoA hydratase
PP1Y_RS12490	COG4771	TonB-dependent receptor
PP1Y_RS12495	COG2814	Major facilitator Superfamily
PP1Y_RS12505	COG1960	acyl-CoA dehydrogenase activity
PP1Y_RS12510	COG0183	Belongs to the thiolase family
PP1Y_RS12515	COG1960	acyl-CoA dehydrogenase activity
PP1Y_RS12540	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS12570	COG1024	Enoyl-CoA hydratase
PP1Y_RS12585	COG2130	NADP-dependent
PP1Y_RS12590	COG0446	pyridine nucleotide-disulphide oxidoreductase
PP1Y_RS12590	COG1902	pentaerythritol trinitrate reductase activity
PP1Y_RS12610	COG4206	TonB-dependent receptor
PP1Y_RS12625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PP1Y_RS12625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PP1Y_RS12645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PP1Y_RS12665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PP1Y_RS12670	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PP1Y_RS12675	COG2080	2 iron, 2 sulfur cluster binding
PP1Y_RS12680	COG1024	Enoyl-CoA hydratase
PP1Y_RS12695	COG4771	TonB-dependent receptor
PP1Y_RS12705	COG2814	Major facilitator Superfamily
PP1Y_RS12715	COG1573	uracil-dna glycosylase
PP1Y_RS12735	COG2130	NADP-dependent
PP1Y_RS12750	COG0028	Belongs to the TPP enzyme family
PP1Y_RS12760	COG2130	NADP-dependent
PP1Y_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS12770	COG4771	TonB-dependent receptor
PP1Y_RS12775	COG2130	NADP-dependent
PP1Y_RS12780	COG4638	Rieske (2fe-2S)
PP1Y_RS12790	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS12795	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS12800	COG1053	succinate dehydrogenase
PP1Y_RS12805	COG0318	PFAM AMP-dependent synthetase and ligase
PP1Y_RS12810	COG4638	Rieske (2fe-2S)
PP1Y_RS12835	COG4638	Rieske (2fe-2S)
PP1Y_RS12845	COG4771	TonB-dependent receptor
PP1Y_RS12850	COG4638	Rieske (2fe-2S)
PP1Y_RS12860	COG4638	Rieske (2fe-2S)
PP1Y_RS12905	COG1960	acyl-CoA dehydrogenase activity
PP1Y_RS12915	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PP1Y_RS12925	COG0183	Belongs to the thiolase family
PP1Y_RS12930	COG1960	acyl-CoA dehydrogenase activity
PP1Y_RS12935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PP1Y_RS12940	COG0022	dehydrogenase e1 component
PP1Y_RS12945	COG0508	dehydrogenase complex catalyzes the overall conversion of
PP1Y_RS12965	COG1758	RNA polymerase activity
PP1Y_RS12970	COG0489	protein tyrosine kinase activity
PP1Y_RS12985	COG0436	Aminotransferase
PP1Y_RS12990	COG0471	metal ion transport
PP1Y_RS12990	COG3273	potassium ion transport
PP1Y_RS13000	COG2003	Belongs to the UPF0758 family
PP1Y_RS13025	COG0356	it plays a direct role in the translocation of protons across the membrane
PP1Y_RS13030	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PP1Y_RS13040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PP1Y_RS13050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PP1Y_RS13055	COG0539	negative regulation of cytoplasmic translation
PP1Y_RS13060	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PP1Y_RS13075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PP1Y_RS13090	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PP1Y_RS13095	COG0228	four-way junction DNA binding
PP1Y_RS13100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PP1Y_RS13115	COG0336	Belongs to the RNA methyltransferase TrmD family
PP1Y_RS13120	COG0335	large ribosomal subunit rRNA binding
PP1Y_RS13135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PP1Y_RS13145	COG0688	phosphatidylethanolamine metabolic process
PP1Y_RS13150	COG1183	phosphatidylcholine synthase activity
PP1Y_RS13155	COG0052	Belongs to the universal ribosomal protein uS2 family
PP1Y_RS13160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PP1Y_RS13170	COG0528	UMP kinase activity
PP1Y_RS13175	COG0233	cytoplasmic translational termination
PP1Y_RS13180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PP1Y_RS13190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PP1Y_RS13195	COG0750	zinc metalloprotease
PP1Y_RS13210	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PP1Y_RS13215	COG0254	rRNA binding
PP1Y_RS13225	COG2032	superoxide dismutase activity
PP1Y_RS13240	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PP1Y_RS13245	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PP1Y_RS13250	COG1138	Cytochrome C-type biogenesis protein
PP1Y_RS13255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PP1Y_RS13270	COG3158	transport of potassium into the cell
PP1Y_RS13280	COG2917	probably involved in intracellular septation
PP1Y_RS13285	COG0552	protein localization to endoplasmic reticulum
PP1Y_RS13290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PP1Y_RS13295	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PP1Y_RS13300	COG3300	MHYT domain
PP1Y_RS13300	COG5001	Diguanylate cyclase
PP1Y_RS13335	COG0583	DNA-binding transcription factor activity
PP1Y_RS13340	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PP1Y_RS13350	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PP1Y_RS13360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PP1Y_RS13365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PP1Y_RS13370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PP1Y_RS13385	COG0582	viral genome integration into host DNA
PP1Y_RS13390	COG0741	lytic transglycosylase activity
PP1Y_RS13390	COG1196	nuclear chromosome segregation
PP1Y_RS13390	COG0739	heme binding
PP1Y_RS13405	COG5642	Protein of unknown function (DUF2384)
PP1Y_RS13440	COG1742	UPF0060 membrane protein
PP1Y_RS13445	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PP1Y_RS13465	COG1475	DNA binding
PP1Y_RS13470	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS13475	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS13480	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS13485	COG4227	nucleotidyltransferase activity
PP1Y_RS13590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PP1Y_RS13760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PP1Y_RS13770	COG3971	2-oxopent-4-enoate hydratase activity
PP1Y_RS13800	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PP1Y_RS13805	COG1012	belongs to the aldehyde dehydrogenase family
PP1Y_RS13830	COG4771	TonB-dependent receptor
PP1Y_RS13835	COG4771	TonB-dependent receptor
PP1Y_RS13845	COG4638	Rieske (2fe-2S)
PP1Y_RS13850	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PP1Y_RS13860	COG0346	lactoylglutathione lyase activity
PP1Y_RS13865	COG4638	Rieske (2fe-2S)
PP1Y_RS13880	COG4638	Rieske (2fe-2S)
PP1Y_RS13885	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PP1Y_RS13915	COG3971	2-oxopent-4-enoate hydratase activity
PP1Y_RS13935	COG1942	4-Oxalocrotonate Tautomerase
PP1Y_RS13975	COG4638	Rieske (2fe-2S)
PP1Y_RS14020	COG2159	amidohydrolase
PP1Y_RS14030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PP1Y_RS14080	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PP1Y_RS14090	COG0574	Belongs to the PEP-utilizing enzyme family
PP1Y_RS14090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PP1Y_RS14095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PP1Y_RS14105	COG0473	3-isopropylmalate dehydrogenase activity
PP1Y_RS14110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PP1Y_RS14260	COG1506	peptidase
PP1Y_RS14260	COG0823	Involved in the tonB-independent uptake of proteins
PP1Y_RS14265	COG4771	TonB-dependent receptor
PP1Y_RS14270	COG3712	iron ion homeostasis
PP1Y_RS14305	COG3916	Acyl-homoserine-lactone synthase
PP1Y_RS14320	COG1396	sequence-specific DNA binding
PP1Y_RS14325	COG0582	viral genome integration into host DNA
PP1Y_RS14365	COG0586	Pfam SNARE associated Golgi protein
PP1Y_RS14400	COG0438	transferase activity, transferring glycosyl groups
PP1Y_RS14410	COG1671	Belongs to the UPF0178 family
PP1Y_RS14450	COG3311	Transcriptional regulator
PP1Y_RS14465	COG3483	tryptophan 2,3-dioxygenase activity
PP1Y_RS14470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PP1Y_RS14480	COG3243	poly(R)-hydroxyalkanoic acid synthase
PP1Y_RS14505	COG0842	Transport permease protein
PP1Y_RS14515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PP1Y_RS14530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PP1Y_RS14535	COG0049	tRNA binding
PP1Y_RS14540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PP1Y_RS14545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PP1Y_RS14555	COG0051	transcription antitermination factor activity, RNA binding
PP1Y_RS14560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PP1Y_RS14565	COG0088	Forms part of the polypeptide exit tunnel
PP1Y_RS14570	COG0089	rRNA binding
PP1Y_RS14575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PP1Y_RS14580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PP1Y_RS14585	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PP1Y_RS14590	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PP1Y_RS14595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PP1Y_RS14600	COG0255	Belongs to the universal ribosomal protein uL29 family
PP1Y_RS14605	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PP1Y_RS14610	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PP1Y_RS14615	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PP1Y_RS14620	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PP1Y_RS14625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PP1Y_RS14630	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PP1Y_RS14635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PP1Y_RS14640	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PP1Y_RS14645	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PP1Y_RS14650	COG1841	ribosomal large subunit assembly
PP1Y_RS14665	COG0200	Binds to the 23S rRNA
PP1Y_RS14675	COG0563	adenylate kinase activity
PP1Y_RS14690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PP1Y_RS14695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PP1Y_RS14700	COG0202	RNA polymerase activity
PP1Y_RS14705	COG0203	ribosomal protein L17
PP1Y_RS14710	COG1505	serine-type exopeptidase activity
PP1Y_RS14760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PP1Y_RS14770	COG0567	Dehydrogenase, E1 component
PP1Y_RS14780	COG0039	L-malate dehydrogenase activity
PP1Y_RS14795	COG4206	TonB-dependent receptor
PP1Y_RS14805	COG4139	cobalamin transport
PP1Y_RS14810	COG1120	ATPase activity
PP1Y_RS14820	COG1959	2 iron, 2 sulfur cluster binding
PP1Y_RS14850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PP1Y_RS14870	COG0137	argininosuccinate synthase activity
PP1Y_RS14875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PP1Y_RS14890	COG0384	phenazine biosynthesis protein PhzF
PP1Y_RS14900	COG2201	protein-glutamate methylesterase activity
PP1Y_RS14915	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PP1Y_RS14935	COG0402	S-adenosylhomocysteine deaminase activity
PP1Y_RS14950	COG0659	secondary active sulfate transmembrane transporter activity
PP1Y_RS14985	COG3437	response regulator, receiver
PP1Y_RS15000	COG0745	RESPONSE REGULATOR receiver
PP1Y_RS15005	COG1366	Belongs to the anti-sigma-factor antagonist family
PP1Y_RS15020	COG1215	transferase activity, transferring glycosyl groups
PP1Y_RS15030	COG3474	cytochrome
PP1Y_RS15040	COG1845	cytochrome c oxidase, subunit III
PP1Y_RS15050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PP1Y_RS15055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PP1Y_RS15065	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PP1Y_RS15070	COG3290	protein histidine kinase activity
PP1Y_RS15080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PP1Y_RS15085	COG1845	cytochrome c oxidase, subunit III
PP1Y_RS15090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PP1Y_RS15095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PP1Y_RS15100	COG0477	Major facilitator Superfamily
PP1Y_RS15105	COG0789	Transcriptional regulator
PP1Y_RS15115	COG0179	Fumarylacetoacetate (FAA) hydrolase
PP1Y_RS15120	COG1522	sequence-specific DNA binding
PP1Y_RS15130	COG1538	Outer membrane efflux protein
PP1Y_RS15140	COG2814	Major facilitator Superfamily
PP1Y_RS15145	COG2201	protein-glutamate methylesterase activity
PP1Y_RS15155	COG2198	Histidine kinase
PP1Y_RS15155	COG0643	Histidine kinase
PP1Y_RS15160	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PP1Y_RS15165	COG2201	protein-glutamate methylesterase activity
PP1Y_RS15170	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PP1Y_RS15175	COG0745	RESPONSE REGULATOR receiver
PP1Y_RS15180	COG0835	chemotaxis
PP1Y_RS15195	COG0534	Mate efflux family protein
PP1Y_RS15200	COG1105	Belongs to the carbohydrate kinase PfkB family
PP1Y_RS15205	COG5001	Diguanylate cyclase
PP1Y_RS15225	COG1482	cell wall glycoprotein biosynthetic process
PP1Y_RS15235	COG0367	asparagine synthase
PP1Y_RS15260	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS15280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PP1Y_RS15300	COG0250	Participates in transcription elongation, termination and antitermination
PP1Y_RS15325	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PP1Y_RS15330	COG0081	regulation of translation
PP1Y_RS15335	COG2226	methyltransferase
PP1Y_RS15345	COG3161	chorismate lyase activity
PP1Y_RS15350	COG1058	Belongs to the CinA family
PP1Y_RS15350	COG1546	Belongs to the CinA family
PP1Y_RS15360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PP1Y_RS15380	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PP1Y_RS15385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PP1Y_RS15410	COG1160	GTP binding
PP1Y_RS15415	COG0628	permease
PP1Y_RS15420	COG1506	peptidase
PP1Y_RS15420	COG4946	Tricorn protease homolog
PP1Y_RS15420	COG0823	Involved in the tonB-independent uptake of proteins
PP1Y_RS15425	COG2070	2-Nitropropane dioxygenase
PP1Y_RS15440	COG2311	Membrane
PP1Y_RS15465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PP1Y_RS15470	COG0540	Belongs to the ATCase OTCase family
PP1Y_RS15475	COG0616	signal peptide processing
PP1Y_RS15485	COG0544	peptidyl-prolyl cis-trans isomerase activity
PP1Y_RS15490	COG0740	serine-type endopeptidase activity
PP1Y_RS15495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PP1Y_RS15515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PP1Y_RS15520	COG0564	pseudouridine synthase activity
PP1Y_RS15535	COG3023	N-Acetylmuramoyl-L-alanine amidase
PP1Y_RS15540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PP1Y_RS15560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PP1Y_RS15565	COG1215	transferase activity, transferring glycosyl groups
PP1Y_RS15575	COG0730	response to heat
PP1Y_RS15590	COG0534	Mate efflux family protein
PP1Y_RS15600	COG0525	valine-tRNA ligase activity
PP1Y_RS15605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PP1Y_RS15610	COG1127	ABC transporter
PP1Y_RS15650	COG0564	pseudouridine synthase activity
PP1Y_RS15655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PP1Y_RS15660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PP1Y_RS15665	COG0545	Peptidyl-prolyl cis-trans isomerase
PP1Y_RS15670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PP1Y_RS15675	COG0154	amidase activity
PP1Y_RS15680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PP1Y_RS15695	COG0542	response to heat
PP1Y_RS15700	COG4771	TonB-dependent receptor
PP1Y_RS15720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PP1Y_RS15745	COG4964	Belongs to the GSP D family
PP1Y_RS15770	COG3422	double-strand break repair
PP1Y_RS15780	COG0328	RNA-DNA hybrid ribonuclease activity
PP1Y_RS15785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PP1Y_RS15790	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PP1Y_RS15810	COG4957	zinc ion binding
PP1Y_RS15825	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PP1Y_RS15830	COG0612	Peptidase, M16
PP1Y_RS15835	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PP1Y_RS15840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PP1Y_RS15845	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
PP1Y_RS15850	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS15855	COG0305	Participates in initiation and elongation during chromosome replication
PP1Y_RS15860	COG5328	Belongs to the UPF0262 family
PP1Y_RS15875	COG2866	Carboxypeptidase
PP1Y_RS15890	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PP1Y_RS15900	COG2308	Evidence 4 Homologs of previously reported genes of
PP1Y_RS15925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PP1Y_RS15930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PP1Y_RS15935	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PP1Y_RS15940	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PP1Y_RS15955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PP1Y_RS15955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PP1Y_RS15960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PP1Y_RS15970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PP1Y_RS15970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PP1Y_RS15975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PP1Y_RS15985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PP1Y_RS15990	COG0825	malonyl-CoA metabolic process
PP1Y_RS15995	COG0439	Biotin carboxylase
PP1Y_RS16000	COG0511	ligase activity, forming carbon-carbon bonds
PP1Y_RS16005	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PP1Y_RS16010	COG0840	transmembrane signaling receptor activity
PP1Y_RS16065	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
PP1Y_RS16100	COG2099	Precorrin-6x reductase
PP1Y_RS16115	COG2875	Belongs to the precorrin methyltransferase family
PP1Y_RS16120	COG1797	cobyrinic acid a,c-diamide synthase activity
PP1Y_RS16130	COG0778	Nitroreductase
PP1Y_RS16145	COG2115	Belongs to the xylose isomerase family
PP1Y_RS16150	COG1070	Carbohydrate kinase
PP1Y_RS16155	COG2211	Major facilitator Superfamily
PP1Y_RS16175	COG2226	methyltransferase
PP1Y_RS16185	COG2211	Major facilitator Superfamily
PP1Y_RS16200	COG1335	isochorismatase
PP1Y_RS16205	COG1414	Transcriptional regulator
PP1Y_RS16225	COG0625	glutathione transferase activity
PP1Y_RS16230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PP1Y_RS16240	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
PP1Y_RS16245	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
PP1Y_RS16260	COG1381	Involved in DNA repair and RecF pathway recombination
PP1Y_RS16265	COG0473	3-isopropylmalate dehydrogenase activity
PP1Y_RS16290	COG2967	ApaG domain
PP1Y_RS16295	COG0583	DNA-binding transcription factor activity
PP1Y_RS16300	COG0501	Belongs to the peptidase M48B family
PP1Y_RS16305	COG1024	Enoyl-CoA hydratase
PP1Y_RS16310	COG1609	Transcriptional regulator
PP1Y_RS16330	COG1012	belongs to the aldehyde dehydrogenase family
PP1Y_RS16340	COG1960	acyl-CoA dehydrogenase activity
PP1Y_RS16345	COG1024	Enoyl-CoA hydratase
PP1Y_RS16350	COG1024	Enoyl-CoA hydratase
PP1Y_RS16385	COG1970	mechanosensitive ion channel activity
PP1Y_RS16395	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PP1Y_RS16405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PP1Y_RS16410	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PP1Y_RS16420	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PP1Y_RS16425	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PP1Y_RS16435	COG0105	UTP biosynthetic process
PP1Y_RS16440	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PP1Y_RS16445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PP1Y_RS16455	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PP1Y_RS16460	COG1045	serine acetyltransferase
PP1Y_RS16470	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS16475	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PP1Y_RS16480	COG0047	phosphoribosylformylglycinamidine synthase activity
PP1Y_RS16490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PP1Y_RS16505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PP1Y_RS16510	COG0546	phosphoglycolate phosphatase activity
PP1Y_RS16515	COG0612	Peptidase, M16
PP1Y_RS16520	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PP1Y_RS16535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PP1Y_RS16585	COG0366	Alpha amylase catalytic
PP1Y_RS16590	COG1082	Xylose isomerase domain protein TIM barrel
PP1Y_RS16615	COG1522	sequence-specific DNA binding
PP1Y_RS16625	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PP1Y_RS16645	COG1862	Preprotein translocase
PP1Y_RS16650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PP1Y_RS16655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PP1Y_RS16675	COG0488	(ABC) transporter
PP1Y_RS16700	COG0287	Prephenate dehydrogenase
PP1Y_RS16700	COG1605	Chorismate mutase
PP1Y_RS16705	COG0142	geranyltranstransferase activity
PP1Y_RS16715	COG5001	Diguanylate cyclase
PP1Y_RS16715	COG3300	MHYT domain
PP1Y_RS16720	COG1643	Atp-dependent helicase
PP1Y_RS16735	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PP1Y_RS16745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PP1Y_RS16765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PP1Y_RS16770	COG0359	binds to the 23S rRNA
PP1Y_RS16775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PP1Y_RS16780	COG0360	Binds together with S18 to 16S ribosomal RNA
PP1Y_RS16795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PP1Y_RS16800	COG2354	Protein conserved in bacteria
PP1Y_RS16805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PP1Y_RS16820	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PP1Y_RS16840	COG0668	transmembrane transport
PP1Y_RS16850	COG5001	Diguanylate cyclase
PP1Y_RS16850	COG3300	MHYT domain
PP1Y_RS16855	COG0481	GTPase activity
PP1Y_RS16875	COG3383	formate dehydrogenase (NAD+) activity
PP1Y_RS16885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PP1Y_RS16890	COG4149	molybdate abc transporter
PP1Y_RS16895	COG0725	ABC transporter, periplasmic molybdate-binding protein
PP1Y_RS16910	COG0477	Major facilitator Superfamily
PP1Y_RS16930	COG0492	ferredoxin-NADP+ reductase activity
PP1Y_RS16985	COG3409	Peptidoglycan-binding domain 1 protein
PP1Y_RS16985	COG3267	Type II secretory pathway component ExeA
PP1Y_RS17010	COG0367	asparagine synthase
PP1Y_RS17020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PP1Y_RS17030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PP1Y_RS17040	COG1530	ribonuclease E activity
PP1Y_RS17050	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PP1Y_RS17100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PP1Y_RS17105	COG0483	inositol monophosphate 1-phosphatase activity
PP1Y_RS17120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PP1Y_RS17125	COG4191	Histidine kinase
PP1Y_RS17130	COG2204	response regulator
PP1Y_RS17135	COG0457	Tetratricopeptide repeat
PP1Y_RS17135	COG0859	PFAM glycosyl transferase family 9
PP1Y_RS17140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PP1Y_RS17145	COG0531	amino acid
PP1Y_RS17160	COG0587	DNA-directed DNA polymerase activity
PP1Y_RS17190	COG1431	PFAM Stem cell self-renewal protein Piwi
PP1Y_RS17240	COG4227	nucleotidyltransferase activity
PP1Y_RS17255	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS17380	COG1968	undecaprenyl-diphosphatase activity
PP1Y_RS17395	COG0672	)-iron permease
PP1Y_RS17400	COG3547	Transposase (IS116 IS110 IS902 family)
PP1Y_RS17455	COG0672	)-iron permease
PP1Y_RS17475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PP1Y_RS17480	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PP1Y_RS17500	COG0126	phosphoglycerate kinase activity
PP1Y_RS17505	COG0167	dihydroorotate dehydrogenase activity
PP1Y_RS17510	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PP1Y_RS17510	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PP1Y_RS17510	COG0674	pyruvate-flavodoxin oxidoreductase activity
PP1Y_RS17510	COG1013	pyruvate-flavodoxin oxidoreductase activity
PP1Y_RS17525	COG3436	PFAM IS66 Orf2 family protein
PP1Y_RS17530	COG4372	Transposase
PP1Y_RS17570	COG0330	HflC and HflK could
PP1Y_RS17580	COG3547	Transposase (IS116 IS110 IS902 family)
PP1Y_RS17585	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS17590	COG0582	viral genome integration into host DNA
PP1Y_RS17595	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS17620	COG3258	Cytochrome c
PP1Y_RS17625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PP1Y_RS17645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PP1Y_RS17650	COG3328	transposase activity
PP1Y_RS17665	COG3459	Glycosyltransferase 36 associated
PP1Y_RS17675	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PP1Y_RS17685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PP1Y_RS17690	COG1595	DNA-templated transcription, initiation
PP1Y_RS17700	COG0574	Belongs to the PEP-utilizing enzyme family
PP1Y_RS17700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PP1Y_RS17710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PP1Y_RS17735	COG0697	spore germination
PP1Y_RS17770	COG3174	membrane
PP1Y_RS17780	COG4716	Myosin-crossreactive antigen
PP1Y_RS17810	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
PP1Y_RS17820	COG1960	acyl-CoA dehydrogenase activity
PP1Y_RS17830	COG4372	Transposase
PP1Y_RS17840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PP1Y_RS17855	COG2963	transposase activity
PP1Y_RS17860	COG0670	Belongs to the BI1 family
PP1Y_RS17880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PP1Y_RS17885	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PP1Y_RS17890	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PP1Y_RS17915	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PP1Y_RS17935	COG4566	intracellular signal transduction
PP1Y_RS17940	COG4191	Histidine kinase
PP1Y_RS17950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PP1Y_RS18150	COG1426	Protein conserved in bacteria
PP1Y_RS18160	COG4957	zinc ion binding
PP1Y_RS18175	COG0582	viral genome integration into host DNA
PP1Y_RS18195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PP1Y_RS18215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PP1Y_RS18225	COG2353	YceI-like domain
PP1Y_RS18230	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PP1Y_RS18235	COG0440	acetolactate synthase activity
PP1Y_RS18240	COG0028	Belongs to the TPP enzyme family
PP1Y_RS18245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PP1Y_RS18250	COG0560	Phosphoserine phosphatase
PP1Y_RS18255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PP1Y_RS18260	COG1722	exodeoxyribonuclease VII activity
PP1Y_RS18265	COG0142	geranyltranstransferase activity
PP1Y_RS18270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PP1Y_RS18280	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PP1Y_RS18285	COG1131	(ABC) transporter
PP1Y_RS18290	COG0842	Transport permease protein
PP1Y_RS18300	COG0343	queuine tRNA-ribosyltransferase activity
PP1Y_RS18315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PP1Y_RS18325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PP1Y_RS18335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PP1Y_RS18340	COG0698	ribose 5-phosphate isomerase
PP1Y_RS18350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PP1Y_RS18365	COG0505	Belongs to the CarA family
PP1Y_RS18380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PP1Y_RS18410	COG0148	phosphopyruvate hydratase activity
PP1Y_RS18425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PP1Y_RS18430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PP1Y_RS18430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PP1Y_RS18440	COG0572	uridine kinase
PP1Y_RS18445	COG1295	ribonuclease BN
PP1Y_RS18445	COG1959	2 iron, 2 sulfur cluster binding
PP1Y_RS18485	COG0772	Belongs to the SEDS family
PP1Y_RS18510	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PP1Y_RS18530	COG0012	GTP binding
PP1Y_RS18545	COG0193	aminoacyl-tRNA hydrolase activity
PP1Y_RS18550	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PP1Y_RS18555	COG3735	TraB family
PP1Y_RS18565	COG0752	glycyl-tRNA synthetase alpha subunit
PP1Y_RS18570	COG0751	glycine-tRNA ligase activity
PP1Y_RS18575	COG0574	Belongs to the PEP-utilizing enzyme family
PP1Y_RS18575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PP1Y_RS18580	COG2226	methyltransferase
PP1Y_RS18585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PP1Y_RS18590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PP1Y_RS18605	COG2814	Major facilitator Superfamily
PP1Y_RS18620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PP1Y_RS18630	COG3876	Protein conserved in bacteria
PP1Y_RS18650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PP1Y_RS18665	COG0187	DNA topoisomerase II activity
PP1Y_RS18675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PP1Y_RS18685	COG0189	ligase activity
PP1Y_RS18690	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS18695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PP1Y_RS18700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PP1Y_RS18705	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PP1Y_RS18710	COG1420	regulation of RNA biosynthetic process
PP1Y_RS18715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PP1Y_RS18735	COG0443	Heat shock 70 kDa protein
PP1Y_RS18740	COG0484	heat shock protein binding
PP1Y_RS18745	COG1752	Esterase of the alpha-beta hydrolase superfamily
PP1Y_RS18765	COG0477	Major facilitator Superfamily
PP1Y_RS18770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PP1Y_RS18775	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
PP1Y_RS18780	COG0442	prolyl-tRNA aminoacylation
PP1Y_RS18790	COG2234	aminopeptidase activity
PP1Y_RS18795	COG0557	exoribonuclease II activity
PP1Y_RS18805	COG0508	dehydrogenase complex catalyzes the overall conversion of
PP1Y_RS18810	COG1607	acyl-coa hydrolase
PP1Y_RS18815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PP1Y_RS18835	COG0477	Major facilitator Superfamily
PP1Y_RS18845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PP1Y_RS18855	COG0784	Response regulator, receiver
PP1Y_RS18855	COG2205	protein histidine kinase activity
PP1Y_RS18855	COG2198	Histidine kinase
PP1Y_RS18885	COG2951	lytic endotransglycosylase activity
PP1Y_RS18890	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PP1Y_RS18900	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PP1Y_RS18905	COG0470	DNA polymerase III
PP1Y_RS18915	COG0084	hydrolase, TatD family'
PP1Y_RS18920	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PP1Y_RS18920	COG0321	lipoyl(octanoyl) transferase activity
PP1Y_RS18930	COG3956	TIGRFAM MazG family protein
PP1Y_RS18935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PP1Y_RS18945	COG2204	response regulator
PP1Y_RS18950	COG5000	phosphorelay sensor kinase activity
PP1Y_RS18955	COG2204	response regulator
PP1Y_RS18970	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PP1Y_RS18970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PP1Y_RS18985	COG2867	negative regulation of translational initiation
PP1Y_RS18990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PP1Y_RS18995	COG0288	reversible hydration of carbon dioxide
PP1Y_RS19005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PP1Y_RS19020	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PP1Y_RS19050	COG0508	dehydrogenase complex catalyzes the overall conversion of
PP1Y_RS19050	COG0022	dehydrogenase e1 component
PP1Y_RS19055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PP1Y_RS19070	COG0842	Transport permease protein
PP1Y_RS19075	COG0842	Transport permease protein
PP1Y_RS19080	COG1131	(ABC) transporter
PP1Y_RS19095	COG0488	(ABC) transporter
PP1Y_RS19105	COG0513	Belongs to the DEAD box helicase family
PP1Y_RS19115	COG1566	PFAM secretion protein HlyD family protein
PP1Y_RS19130	COG1846	Transcriptional regulator
PP1Y_RS19140	COG1492	cobalamin metabolic process
PP1Y_RS19155	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PP1Y_RS19165	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PP1Y_RS19185	COG0405	Gamma-glutamyltransferase
PP1Y_RS19245	COG4964	Belongs to the GSP D family
PP1Y_RS19280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PP1Y_RS19320	COG1215	transferase activity, transferring glycosyl groups
PP1Y_RS19385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PP1Y_RS19395	COG0071	Belongs to the small heat shock protein (HSP20) family
PP1Y_RS19400	COG0840	transmembrane signaling receptor activity
PP1Y_RS19410	COG0504	CTP synthase activity
PP1Y_RS19420	COG0149	triose-phosphate isomerase activity
PP1Y_RS19430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PP1Y_RS19435	COG3698	Phosphodiester glycosidase
PP1Y_RS19445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PP1Y_RS19450	COG0134	indole-3-glycerol-phosphate synthase activity
PP1Y_RS19455	COG0315	cyclic pyranopterin monophosphate synthase activity
PP1Y_RS19460	COG0303	'Molybdopterin
PP1Y_RS19465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PP1Y_RS19475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PP1Y_RS19480	COG0372	Belongs to the citrate synthase family
PP1Y_RS19490	COG2205	protein histidine kinase activity
PP1Y_RS19525	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PP1Y_RS19535	COG1007	ATP synthesis coupled electron transport
PP1Y_RS19550	COG0713	ATP synthesis coupled electron transport
PP1Y_RS19560	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PP1Y_RS19565	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PP1Y_RS19570	COG1034	ATP synthesis coupled electron transport
PP1Y_RS19575	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PP1Y_RS19580	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
PP1Y_RS19595	COG0649	NAD binding
PP1Y_RS19600	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PP1Y_RS19605	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PP1Y_RS19610	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PP1Y_RS19615	COG0183	Belongs to the thiolase family
PP1Y_RS19630	COG0004	ammonium transporteR
PP1Y_RS19645	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PP1Y_RS19655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PP1Y_RS19675	COG0488	(ABC) transporter
PP1Y_RS19700	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
PP1Y_RS19705	COG0668	transmembrane transport
PP1Y_RS19735	COG0776	regulation of translation
PP1Y_RS19740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PP1Y_RS19745	COG0416	fatty acid biosynthetic process
PP1Y_RS19750	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PP1Y_RS19760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PP1Y_RS19765	COG2932	Transcriptional regulator
PP1Y_RS19780	COG0028	Belongs to the TPP enzyme family
PP1Y_RS19785	COG0215	cysteine-tRNA ligase activity
PP1Y_RS19805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PP1Y_RS19820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PP1Y_RS19820	COG2169	Transcriptional regulator
PP1Y_RS19830	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PP1Y_RS19835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PP1Y_RS19840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PP1Y_RS19845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PP1Y_RS19850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PP1Y_RS19875	COG0385	Bile acid
PP1Y_RS19880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PP1Y_RS19885	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PP1Y_RS19895	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PP1Y_RS19905	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PP1Y_RS19935	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS19940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PP1Y_RS19945	COG2189	Belongs to the N(4) N(6)-methyltransferase family
PP1Y_RS19955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PP1Y_RS19960	COG2133	pyrroloquinoline quinone binding
PP1Y_RS19975	COG0494	nUDIX hydrolase
PP1Y_RS19990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PP1Y_RS19995	COG0693	protein deglycase activity
PP1Y_RS20005	COG1104	cysteine desulfurase activity
PP1Y_RS20015	COG2945	thiolester hydrolase activity
PP1Y_RS20035	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PP1Y_RS20040	COG0745	RESPONSE REGULATOR receiver
PP1Y_RS20045	COG0642	Histidine kinase
PP1Y_RS20050	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PP1Y_RS20055	COG1660	Displays ATPase and GTPase activities
PP1Y_RS20070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PP1Y_RS20080	COG1322	Protein conserved in bacteria
PP1Y_RS20085	COG0242	peptide deformylase activity
PP1Y_RS20090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PP1Y_RS20095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PP1Y_RS20100	COG0101	tRNA pseudouridine synthase activity
PP1Y_RS20115	COG1733	regulation of RNA biosynthetic process
PP1Y_RS20120	COG0625	glutathione transferase activity
PP1Y_RS20125	COG5507	3-demethylubiquinone-9 3-methyltransferase
PP1Y_RS20160	COG0271	Belongs to the BolA IbaG family
PP1Y_RS20165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PP1Y_RS20170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PP1Y_RS20175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PP1Y_RS20180	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PP1Y_RS20185	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
PP1Y_RS20205	COG0322	excinuclease ABC activity
PP1Y_RS20215	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PP1Y_RS20220	COG0424	maF-like protein
PP1Y_RS20235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PP1Y_RS20240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PP1Y_RS20265	COG1218	3'(2'),5'-bisphosphate nucleotidase
PP1Y_RS20275	COG0175	sulfate reduction
PP1Y_RS20285	COG0352	thiamine-phosphate diphosphorylase activity
PP1Y_RS20295	COG0840	transmembrane signaling receptor activity
PP1Y_RS20300	COG3588	fructose-bisphosphate aldolase
PP1Y_RS20305	COG0126	phosphoglycerate kinase activity
PP1Y_RS20315	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PP1Y_RS20320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PP1Y_RS20335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PP1Y_RS20375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PP1Y_RS20385	COG0840	transmembrane signaling receptor activity
PP1Y_RS20395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PP1Y_RS20415	COG3264	Mechanosensitive ion channel
PP1Y_RS20415	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PP1Y_RS20445	COG3590	peptidase
PP1Y_RS20475	COG1054	Belongs to the UPF0176 family
PP1Y_RS20490	COG2197	response regulator
PP1Y_RS20500	COG0784	Response regulator, receiver
PP1Y_RS20515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PP1Y_RS20530	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS20535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PP1Y_RS20545	COG5001	Diguanylate cyclase
PP1Y_RS20545	COG1716	ATPase activity
PP1Y_RS20550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PP1Y_RS20580	COG0653	protein targeting
PP1Y_RS20590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PP1Y_RS20595	COG0625	glutathione transferase activity
PP1Y_RS20600	COG0483	inositol monophosphate 1-phosphatase activity
PP1Y_RS20610	COG1074	ATP-dependent DNA helicase activity
PP1Y_RS20620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PP1Y_RS20625	COG3178	'Phosphotransferase
PP1Y_RS20630	COG0802	atpase or kinase
PP1Y_RS20635	COG2205	protein histidine kinase activity
PP1Y_RS20640	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PP1Y_RS20650	COG0678	peroxiredoxin activity
PP1Y_RS20655	COG0300	oxidoreductase activity
PP1Y_RS20665	COG0302	gtp cyclohydrolase
PP1Y_RS20670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PP1Y_RS20695	COG0494	nUDIX hydrolase
PP1Y_RS20715	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS20725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PP1Y_RS20730	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PP1Y_RS20740	COG3104	oligopeptide transport
PP1Y_RS20750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PP1Y_RS20750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PP1Y_RS20755	COG4770	biotin carboxylase activity
PP1Y_RS20765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PP1Y_RS20775	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PP1Y_RS20775	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PP1Y_RS20780	COG0346	lactoylglutathione lyase activity
PP1Y_RS20785	COG0183	Belongs to the thiolase family
PP1Y_RS20790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PP1Y_RS20810	COG0166	Belongs to the GPI family
PP1Y_RS20815	COG0681	Belongs to the peptidase S26 family
PP1Y_RS20820	COG0571	ribonuclease III activity
PP1Y_RS20825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PP1Y_RS20835	COG2814	Major facilitator Superfamily
PP1Y_RS20845	COG1754	DNA topoisomerase type I activity
PP1Y_RS20845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PP1Y_RS20850	COG0758	DNA mediated transformation
PP1Y_RS20855	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PP1Y_RS20860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PP1Y_RS20870	COG0156	8-amino-7-oxononanoate synthase activity
PP1Y_RS20875	COG1902	pentaerythritol trinitrate reductase activity
PP1Y_RS20925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PP1Y_RS20940	COG0129	dihydroxy-acid dehydratase activity
PP1Y_RS20955	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PP1Y_RS20970	COG0741	lytic transglycosylase activity
PP1Y_RS20975	COG0521	Mo-molybdopterin cofactor biosynthetic process
PP1Y_RS20985	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PP1Y_RS20990	COG0033	Phosphoglucomutase
PP1Y_RS21000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PP1Y_RS21010	COG0284	orotidine-5'-phosphate decarboxylase activity
PP1Y_RS21035	COG0133	tryptophan synthase activity
PP1Y_RS21040	COG0159	tryptophan synthase activity
PP1Y_RS21045	COG0285	dihydrofolate synthase activity
PP1Y_RS21050	COG2223	nitrite transmembrane transporter activity
PP1Y_RS21055	COG1187	pseudouridine synthase activity
PP1Y_RS21060	COG0742	ribosomal rna small subunit methyltransferase
PP1Y_RS21070	COG0210	DNA helicase
PP1Y_RS21075	COG0513	Belongs to the DEAD box helicase family
PP1Y_RS21085	COG0277	FAD linked oxidase domain protein
PP1Y_RS21110	COG0538	isocitrate dehydrogenase activity
PP1Y_RS21125	COG0318	PFAM AMP-dependent synthetase and ligase
PP1Y_RS21135	COG0386	Belongs to the glutathione peroxidase family
PP1Y_RS21145	COG1136	(ABC) transporter
PP1Y_RS21155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PP1Y_RS21160	COG4221	oxidoreductase activity
PP1Y_RS21170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PP1Y_RS21175	COG0415	Belongs to the DNA photolyase family
PP1Y_RS21180	COG0671	phosphoesterase, PA-phosphatase related
PP1Y_RS21185	COG1013	pyruvate-flavodoxin oxidoreductase activity
PP1Y_RS21190	COG0674	pyruvate-flavodoxin oxidoreductase activity
PP1Y_RS21190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PP1Y_RS21195	COG1051	belongs to the nudix hydrolase family
PP1Y_RS21220	COG2321	neutral zinc metallopeptidase
PP1Y_RS21235	COG3682	Transcriptional regulator
PP1Y_RS21250	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PP1Y_RS21265	COG2264	protein methyltransferase activity
PP1Y_RS21275	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PP1Y_RS21290	COG0497	DNA recombination
PP1Y_RS21300	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PP1Y_RS21310	COG2066	Belongs to the glutaminase family
PP1Y_RS21315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PP1Y_RS21320	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PP1Y_RS21340	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PP1Y_RS21350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PP1Y_RS21355	COG0741	lytic transglycosylase activity
PP1Y_RS21380	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PP1Y_RS21420	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PP1Y_RS21430	COG0574	Belongs to the PEP-utilizing enzyme family
PP1Y_RS21430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PP1Y_RS21435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PP1Y_RS21445	COG0473	3-isopropylmalate dehydrogenase activity
PP1Y_RS21450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PP1Y_RS21465	COG0633	Ferredoxin
PP1Y_RS21485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PP1Y_RS21540	COG4638	Rieske (2fe-2S)
PP1Y_RS21560	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PP1Y_RS21570	COG0183	Belongs to the thiolase family
PP1Y_RS21575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PP1Y_RS21585	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS21615	COG4584	PFAM Integrase catalytic
PP1Y_RS21620	COG1484	DNA-dependent DNA replication
PP1Y_RS21655	COG1012	belongs to the aldehyde dehydrogenase family
PP1Y_RS21665	COG1942	4-Oxalocrotonate Tautomerase
PP1Y_RS21685	COG3971	2-oxopent-4-enoate hydratase activity
PP1Y_RS21715	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PP1Y_RS21720	COG4638	Rieske (2fe-2S)
PP1Y_RS21735	COG4638	Rieske (2fe-2S)
PP1Y_RS21740	COG0346	lactoylglutathione lyase activity
PP1Y_RS21750	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PP1Y_RS21755	COG4638	Rieske (2fe-2S)
PP1Y_RS21765	COG4771	TonB-dependent receptor
PP1Y_RS21770	COG4771	TonB-dependent receptor
PP1Y_RS21795	COG1012	belongs to the aldehyde dehydrogenase family
PP1Y_RS21800	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PP1Y_RS21830	COG3971	2-oxopent-4-enoate hydratase activity
PP1Y_RS21840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PP1Y_RS21845	COG2814	Major facilitator Superfamily
PP1Y_RS21875	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS21885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PP1Y_RS21890	COG0183	Belongs to the thiolase family
PP1Y_RS21900	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PP1Y_RS22000	COG4974	Belongs to the 'phage' integrase family
PP1Y_RS22020	COG4227	nucleotidyltransferase activity
PP1Y_RS22060	COG4957	zinc ion binding
PP1Y_RS22095	COG2319	Wd-40 repeat
PP1Y_RS22095	COG5635	Nacht domain
PP1Y_RS22140	COG4771	TonB-dependent receptor
PP1Y_RS22175	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS22180	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS22190	COG1053	succinate dehydrogenase
PP1Y_RS22200	COG4569	acetaldehyde dehydrogenase (acetylating) activity
PP1Y_RS22220	COG0405	Gamma-glutamyltransferase
PP1Y_RS22225	COG2267	carboxylic ester hydrolase activity
PP1Y_RS22245	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS22250	COG0277	FAD linked oxidase domain protein
PP1Y_RS22255	COG0346	lactoylglutathione lyase activity
PP1Y_RS22265	COG0385	Bile acid
PP1Y_RS22270	COG0583	DNA-binding transcription factor activity
PP1Y_RS22280	COG3385	transposase activity
PP1Y_RS22290	COG1960	acyl-CoA dehydrogenase activity
PP1Y_RS22310	COG4771	TonB-dependent receptor
PP1Y_RS22320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PP1Y_RS22325	COG0179	Fumarylacetoacetate (FAA) hydrolase
PP1Y_RS22415	COG0438	transferase activity, transferring glycosyl groups
PP1Y_RS22420	COG1596	polysaccharide export
PP1Y_RS22425	COG0297	glycogen (starch) synthase activity
PP1Y_RS22430	COG0489	protein tyrosine kinase activity
PP1Y_RS22430	COG3206	protein involved in exopolysaccharide biosynthesis
PP1Y_RS22440	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
PP1Y_RS22455	COG0110	maltose O-acetyltransferase activity
PP1Y_RS22475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PP1Y_RS22480	COG2010	Cytochrome c
PP1Y_RS22480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PP1Y_RS22485	COG0489	protein tyrosine kinase activity
PP1Y_RS22495	COG0330	HflC and HflK could
PP1Y_RS22505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PP1Y_RS22510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PP1Y_RS22515	COG1585	Membrane protein implicated in regulation of membrane protease activity
PP1Y_RS22520	COG0330	HflC and HflK could
PP1Y_RS22555	COG0427	acetyl-CoA hydrolase
PP1Y_RS22560	COG0527	aspartate kinase activity
PP1Y_RS22565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PP1Y_RS22575	COG1393	Belongs to the ArsC family
PP1Y_RS22585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PP1Y_RS22590	COG0457	Tetratricopeptide repeat
PP1Y_RS22600	COG3634	alkyl hydroperoxide reductase activity
PP1Y_RS22620	COG4395	Tim44
PP1Y_RS22625	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PP1Y_RS22635	COG0180	Tryptophanyl-tRNA synthetase
PP1Y_RS22640	COG2258	MOSC domain
PP1Y_RS22655	COG0756	dUTP diphosphatase activity
PP1Y_RS22660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PP1Y_RS22670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PP1Y_RS22675	COG2226	methyltransferase
PP1Y_RS22685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PP1Y_RS22690	COG0268	Binds directly to 16S ribosomal RNA
PP1Y_RS22695	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PP1Y_RS22710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PP1Y_RS22715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PP1Y_RS22720	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PP1Y_RS22725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PP1Y_RS22735	COG1301	dicarboxylic acid transport
PP1Y_RS22740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PP1Y_RS22750	COG0625	glutathione transferase activity
PP1Y_RS22755	COG0306	phosphate transporter
PP1Y_RS22760	COG1392	Phosphate transport regulator
PP1Y_RS22765	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PP1Y_RS22770	COG0706	membrane insertase activity
PP1Y_RS22775	COG0594	ribonuclease P activity
PP1Y_RS22780	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PP1Y_RS22795	COG0606	chelatase, subunit chli
PP1Y_RS22800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PP1Y_RS22800	COG2226	methyltransferase
PP1Y_RS22800	COG0596	Alpha beta hydrolase
PP1Y_RS22810	COG0556	nucleotide-excision repair
PP1Y_RS22840	COG2304	oxidoreductase activity
PP1Y_RS22850	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PP1Y_RS22855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PP1Y_RS22860	COG0181	hydroxymethylbilane synthase activity
PP1Y_RS22875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PP1Y_RS22955	COG4786	Flagellar basal body rod
PP1Y_RS22970	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PP1Y_RS22975	COG1706	bacterial-type flagellum-dependent cell motility
PP1Y_RS22985	COG4786	Flagellar basal body rod
PP1Y_RS22985	COG1256	bacterial-type flagellum assembly
PP1Y_RS23000	COG1360	Flagellar Motor Protein
PP1Y_RS23020	COG1677	Flagellar hook-basal body complex protein FliE
PP1Y_RS23030	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PP1Y_RS23040	COG1157	protein secretion by the type III secretion system
PP1Y_RS23080	COG1987	bacterial-type flagellum assembly
PP1Y_RS23095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PP1Y_RS23095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PP1Y_RS23105	COG4566	intracellular signal transduction
PP1Y_RS23115	COG0436	Aminotransferase
PP1Y_RS23125	COG1230	cation diffusion facilitator family transporter
PP1Y_RS23140	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PP1Y_RS23145	COG1137	ATPase activity
PP1Y_RS23155	COG0312	modulator of DNA gyrase
PP1Y_RS23160	COG1960	acyl-CoA dehydrogenase activity
PP1Y_RS23165	COG1024	Enoyl-CoA hydratase
PP1Y_RS23165	COG1250	3-hydroxyacyl-CoA dehydrogenase
PP1Y_RS23170	COG0183	Belongs to the thiolase family
PP1Y_RS23185	COG0318	PFAM AMP-dependent synthetase and ligase
PP1Y_RS23200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PP1Y_RS23245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PP1Y_RS23245	COG0519	Catalyzes the synthesis of GMP from XMP
PP1Y_RS23265	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PP1Y_RS23270	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PP1Y_RS23290	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS23295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PP1Y_RS23310	COG2226	methyltransferase
PP1Y_RS23330	COG0646	methionine synthase
PP1Y_RS23330	COG1410	methionine synthase
PP1Y_RS23340	COG0514	ATP-dependent DNA helicase (RecQ)
PP1Y_RS23345	COG2989	Protein conserved in bacteria
PP1Y_RS23355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PP1Y_RS23365	COG2255	four-way junction helicase activity
PP1Y_RS23370	COG0632	four-way junction helicase activity
PP1Y_RS23380	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PP1Y_RS23385	COG0217	transcriptional regulatory protein
PP1Y_RS23390	COG0393	Putative heavy-metal-binding
PP1Y_RS23395	COG3750	Belongs to the UPF0335 family
PP1Y_RS23405	COG0469	pyruvate kinase activity
PP1Y_RS23425	COG1674	ftsk spoiiie
PP1Y_RS23430	COG0475	glutathione-regulated potassium exporter activity
PP1Y_RS23430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PP1Y_RS23435	COG1522	sequence-specific DNA binding
PP1Y_RS23440	COG0686	Belongs to the AlaDH PNT family
PP1Y_RS23445	COG3706	GGDEF domain
PP1Y_RS23485	COG0433	COG0433 Predicted ATPase
PP1Y_RS23490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PP1Y_RS23490	COG0512	Glutamine amidotransferase of anthranilate synthase
PP1Y_RS23500	COG0564	pseudouridine synthase activity
PP1Y_RS23520	COG0747	negative chemotaxis
PP1Y_RS23570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PP1Y_RS23575	COG0156	8-amino-7-oxononanoate synthase activity
PP1Y_RS23585	COG5425	PFAM Usg family protein
PP1Y_RS23605	COG4695	Portal protein
PP1Y_RS23685	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PP1Y_RS23685	COG2885	chlorophyll binding
PP1Y_RS23690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PP1Y_RS23705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PP1Y_RS23710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PP1Y_RS23715	COG1278	Cold shock
PP1Y_RS23725	COG0347	Belongs to the P(II) protein family
PP1Y_RS23730	COG0004	ammonium transporteR
PP1Y_RS23735	COG0347	Belongs to the P(II) protein family
PP1Y_RS23745	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PP1Y_RS23750	COG4221	oxidoreductase activity
PP1Y_RS23760	COG0072	phenylalanine-tRNA ligase activity
PP1Y_RS23765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PP1Y_RS23775	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PP1Y_RS23780	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PP1Y_RS23805	COG1494	fructose-1,6-bisphosphatase
PP1Y_RS23845	COG1201	RNA secondary structure unwinding
PP1Y_RS23865	COG1192	Involved in chromosome partitioning
PP1Y_RS23870	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PP1Y_RS23885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PP1Y_RS23905	COG0583	DNA-binding transcription factor activity
PP1Y_RS23950	COG2943	transferase activity, transferring hexosyl groups
PP1Y_RS23955	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PP1Y_RS23970	COG4771	TonB-dependent receptor
PP1Y_RS23975	COG1472	Belongs to the glycosyl hydrolase 3 family
PP1Y_RS23980	COG1609	Transcriptional regulator
PP1Y_RS24005	COG1595	DNA-templated transcription, initiation
PP1Y_RS24010	COG1609	Transcriptional regulator
PP1Y_RS24025	COG1621	beta-fructofuranosidase activity
PP1Y_RS24030	COG1940	carbohydrate kinase activity
PP1Y_RS24050	COG1028	Short-chain dehydrogenase reductase Sdr
PP1Y_RS24070	COG2197	response regulator
PP1Y_RS24145	COG0513	Belongs to the DEAD box helicase family
PP1Y_RS24160	COG2814	Major facilitator Superfamily
PP1Y_RS24165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PP1Y_RS24170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PP1Y_RS24180	COG1612	heme a metabolic process
PP1Y_RS24195	COG2022	thiamine diphosphate biosynthetic process
PP1Y_RS24210	COG0387	Pfam Sodium calcium exchanger
PP1Y_RS24215	COG1022	Amp-dependent synthetase and ligase
PP1Y_RS24220	COG0167	dihydroorotate dehydrogenase activity
PP1Y_RS24230	COG0719	Fe-S assembly protein
PP1Y_RS24240	COG0396	ATPase activity
PP1Y_RS24245	COG0719	Fe-S assembly protein
PP1Y_RS24250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PP1Y_RS24255	COG2151	metal-sulfur cluster biosynthetic enzyme
PP1Y_RS24280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PP1Y_RS24295	COG0151	Belongs to the GarS family
PP1Y_RS24300	COG1570	exodeoxyribonuclease VII activity
PP1Y_RS24320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PP1Y_RS24325	COG0590	tRNA wobble adenosine to inosine editing
PP1Y_RS24345	COG3279	Response regulator of the LytR AlgR family
PP1Y_RS24350	COG3275	phosphorelay sensor kinase activity
PP1Y_RS24370	COG1695	Transcriptional regulator
PP1Y_RS24410	COG3275	phosphorelay sensor kinase activity
PP1Y_RS24420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PP1Y_RS24445	COG0617	tRNA 3'-terminal CCA addition
PP1Y_RS24445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PP1Y_RS24445	COG3620	sequence-specific DNA binding
PP1Y_RS24475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PP1Y_RS24480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PP1Y_RS24485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PP1Y_RS24490	COG0237	dephospho-CoA kinase activity
PP1Y_RS24495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PP1Y_RS24500	COG0424	maF-like protein
PP1Y_RS24505	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PP1Y_RS24560	COG0019	diaminopimelate decarboxylase activity
PP1Y_RS24650	COG1216	Glycosyl transferase, family 2
PP1Y_RS24650	COG1442	glycosyl transferase family 8
PP1Y_RS24665	COG2226	methyltransferase
PP1Y_RS24715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PP1Y_RS24720	COG5002	protein histidine kinase activity
PP1Y_RS24760	COG0739	heme binding
PP1Y_RS24775	COG4251	negative regulation of phosphorylation