locus-tag	class	description
AKN87_RS00010	COG1286	toxin biosynthetic process
AKN87_RS00025	COG2925	Exonuclease
AKN87_RS00040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKN87_RS00045	COG0544	peptidyl-prolyl cis-trans isomerase activity
AKN87_RS00055	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AKN87_RS00060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AKN87_RS00070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AKN87_RS00075	COG3089	Belongs to the UPF0270 family
AKN87_RS00080	COG0431	NADPH-dependent FMN reductase
AKN87_RS00085	COG2056	Na+-H+ antiporter family
AKN87_RS00090	COG2837	iron assimilation
AKN87_RS00095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AKN87_RS00105	COG2914	Belongs to the UPF0125 (RnfH) family
AKN87_RS00110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AKN87_RS00120	COG2326	polyphosphate kinase activity
AKN87_RS00125	COG3081	Nucleoid-associated protein
AKN87_RS00140	COG3171	Protein conserved in bacteria
AKN87_RS00150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKN87_RS00170	COG2610	gluconate transmembrane transporter activity
AKN87_RS00180	COG2084	Dehydrogenase
AKN87_RS00185	COG3622	Belongs to the hyi family
AKN87_RS00205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AKN87_RS00210	COG0352	thiamine-phosphate diphosphorylase activity
AKN87_RS00230	COG0495	leucyl-tRNA aminoacylation
AKN87_RS00240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKN87_RS00240	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AKN87_RS00250	COG1196	nuclear chromosome segregation
AKN87_RS00255	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AKN87_RS00260	COG1546	Belongs to the CinA family
AKN87_RS00270	COG2137	regulation of response to DNA damage stimulus
AKN87_RS00285	COG0513	Belongs to the DEAD box helicase family
AKN87_RS00290	COG1946	Acyl-CoA thioesterase
AKN87_RS00325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AKN87_RS00330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AKN87_RS00335	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AKN87_RS00340	COG0772	Belongs to the SEDS family
AKN87_RS00350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AKN87_RS00355	COG1181	Belongs to the D-alanine--D-alanine ligase family
AKN87_RS00370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AKN87_RS00375	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AKN87_RS00385	COG0653	protein targeting
AKN87_RS00395	COG0494	nUDIX hydrolase
AKN87_RS00400	COG2096	Adenosyltransferase
AKN87_RS00410	COG1666	GTP binding
AKN87_RS00415	COG0322	excinuclease ABC activity
AKN87_RS00425	COG0557	exoribonuclease II activity
AKN87_RS00430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKN87_RS00435	COG0360	Binds together with S18 to 16S ribosomal RNA
AKN87_RS00450	COG0359	binds to the 23S rRNA
AKN87_RS00455	COG0305	Participates in initiation and elongation during chromosome replication
AKN87_RS00465	COG5002	protein histidine kinase activity
AKN87_RS00465	COG2205	protein histidine kinase activity
AKN87_RS00465	COG0784	Response regulator, receiver
AKN87_RS00475	COG0138	bifunctional purine biosynthesis protein purh
AKN87_RS00505	COG2135	peptidase activity
AKN87_RS00515	COG1660	Displays ATPase and GTPase activities
AKN87_RS00530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AKN87_RS00555	COG3201	nicotinamide mononucleotide transporter
AKN87_RS00565	COG1846	Transcriptional regulator
AKN87_RS00570	COG2814	Major facilitator Superfamily
AKN87_RS00575	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AKN87_RS00590	COG1805	sodium ion transport
AKN87_RS00615	COG1477	protein flavinylation
AKN87_RS00625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AKN87_RS00635	COG4591	ABC-type transport system involved in lipoprotein release permease component
AKN87_RS00650	COG0436	Aminotransferase
AKN87_RS00655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AKN87_RS00665	COG4536	flavin adenine dinucleotide binding
AKN87_RS00675	COG1399	metal-binding, possibly nucleic acid-binding protein
AKN87_RS00680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AKN87_RS00685	COG0416	fatty acid biosynthetic process
AKN87_RS00700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AKN87_RS00705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AKN87_RS00710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AKN87_RS00715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AKN87_RS00720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AKN87_RS00735	COG0084	hydrolase, TatD family'
AKN87_RS00740	COG1643	Atp-dependent helicase
AKN87_RS00745	COG0826	peptidase U32
AKN87_RS00755	COG1214	PFAM Peptidase M22, glycoprotease
AKN87_RS00760	COG0742	ribosomal rna small subunit methyltransferase
AKN87_RS00780	COG0564	pseudouridine synthase activity
AKN87_RS00795	COG3720	iron ion transport
AKN87_RS00805	COG0848	biopolymer transport protein
AKN87_RS00810	COG4558	Periplasmic binding protein
AKN87_RS00815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKN87_RS00820	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AKN87_RS00840	COG0165	Argininosuccinate lyase
AKN87_RS00855	COG0530	calcium, potassium:sodium antiporter activity
AKN87_RS00860	COG0471	metal ion transport
AKN87_RS00865	COG0513	Belongs to the DEAD box helicase family
AKN87_RS00885	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AKN87_RS00900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AKN87_RS00950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AKN87_RS00965	COG1968	undecaprenyl-diphosphatase activity
AKN87_RS00995	COG0542	response to heat
AKN87_RS01000	COG0586	Pfam SNARE associated Golgi protein
AKN87_RS01005	COG2094	Belongs to the DNA glycosylase MPG family
AKN87_RS01010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AKN87_RS01015	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AKN87_RS01030	COG0768	penicillin binding
AKN87_RS01035	COG0772	Belongs to the SEDS family
AKN87_RS01040	COG2951	lytic endotransglycosylase activity
AKN87_RS01050	COG1686	Belongs to the peptidase S11 family
AKN87_RS01060	COG0321	lipoyl(octanoyl) transferase activity
AKN87_RS01065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AKN87_RS01075	COG2264	protein methyltransferase activity
AKN87_RS01105	COG0514	ATP-dependent DNA helicase (RecQ)
AKN87_RS01110	COG2076	Multidrug Resistance protein
AKN87_RS01120	COG5592	hemerythrin HHE cation binding domain
AKN87_RS01125	COG0602	queuosine metabolic process
AKN87_RS01130	COG0720	synthase
AKN87_RS01150	COG2823	Periplasmic or secreted lipoprotein
AKN87_RS01155	COG0363	glucosamine-6-phosphate deaminase activity
AKN87_RS01170	COG2967	ApaG domain
AKN87_RS01175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AKN87_RS01180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKN87_RS01190	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AKN87_RS01200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AKN87_RS01210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AKN87_RS01215	COG0795	lipopolysaccharide-transporting ATPase activity
AKN87_RS01220	COG0795	lipopolysaccharide-transporting ATPase activity
AKN87_RS01225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AKN87_RS01230	COG2027	D-alanyl-D-alanine carboxypeptidase
AKN87_RS01240	COG2847	Copper chaperone PCu(A)C
AKN87_RS01265	COG1278	Cold shock
AKN87_RS01270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AKN87_RS01275	COG0542	response to heat
AKN87_RS01290	COG2030	dehydratase
AKN87_RS01295	COG0318	PFAM AMP-dependent synthetase and ligase
AKN87_RS01300	COG0589	response to stress
AKN87_RS01305	COG1252	NADH dehydrogenase
AKN87_RS01315	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AKN87_RS01325	COG0148	phosphopyruvate hydratase activity
AKN87_RS01330	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AKN87_RS01335	COG0504	CTP synthase activity
AKN87_RS01360	COG1199	ATP-dependent helicase activity
AKN87_RS01370	COG0167	dihydroorotate dehydrogenase activity
AKN87_RS01375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKN87_RS01385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKN87_RS01395	COG3243	poly(R)-hydroxyalkanoic acid synthase
AKN87_RS01405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AKN87_RS01420	COG0800	Aldolase
AKN87_RS01435	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AKN87_RS01440	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AKN87_RS01445	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AKN87_RS01460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AKN87_RS01465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AKN87_RS01480	COG2989	Protein conserved in bacteria
AKN87_RS01485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AKN87_RS01495	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AKN87_RS01500	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AKN87_RS01505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AKN87_RS01510	COG0072	phenylalanine-tRNA ligase activity
AKN87_RS01515	COG0776	regulation of translation
AKN87_RS01550	COG0693	protein deglycase activity
AKN87_RS01560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AKN87_RS01580	COG0515	serine threonine protein kinase
AKN87_RS01580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AKN87_RS01630	COG0582	viral genome integration into host DNA
AKN87_RS01680	COG2076	Multidrug Resistance protein
AKN87_RS01700	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AKN87_RS01815	COG0740	serine-type endopeptidase activity
AKN87_RS01915	COG0542	response to heat
AKN87_RS01925	COG0189	ligase activity
AKN87_RS01940	COG2223	nitrite transmembrane transporter activity
AKN87_RS01960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AKN87_RS01970	COG2321	neutral zinc metallopeptidase
AKN87_RS01975	COG4988	ABC transporter
AKN87_RS01980	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AKN87_RS01990	COG0328	RNA-DNA hybrid ribonuclease activity
AKN87_RS01995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AKN87_RS02060	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AKN87_RS02070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AKN87_RS02075	COG1115	amino acid carrier protein
AKN87_RS02095	COG0425	Belongs to the sulfur carrier protein TusA family
AKN87_RS02100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AKN87_RS02105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AKN87_RS02125	COG0308	aminopeptidase N
AKN87_RS02140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AKN87_RS02155	COG1335	isochorismatase
AKN87_RS02160	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AKN87_RS02165	COG4181	ATPase activity
AKN87_RS02180	COG0402	S-adenosylhomocysteine deaminase activity
AKN87_RS02220	COG0418	dihydroorotase activity
AKN87_RS02225	COG0137	argininosuccinate synthase activity
AKN87_RS02230	COG0346	lactoylglutathione lyase activity
AKN87_RS02245	COG1028	Short-chain dehydrogenase reductase Sdr
AKN87_RS02255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AKN87_RS02260	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AKN87_RS02265	COG2252	PERMEase
AKN87_RS02280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AKN87_RS02285	COG0066	3-isopropylmalate dehydratase activity
AKN87_RS02310	COG0668	transmembrane transport
AKN87_RS02315	COG4133	protoheme IX ABC transporter activity
AKN87_RS02340	COG1138	Cytochrome C-type biogenesis protein
AKN87_RS02360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AKN87_RS02365	COG1360	Flagellar Motor Protein
AKN87_RS02380	COG3133	Outer membrane lipoprotein
AKN87_RS02425	COG1025	Belongs to the peptidase M16 family
AKN87_RS02455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AKN87_RS02495	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AKN87_RS02500	COG1074	ATP-dependent DNA helicase activity
AKN87_RS02505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AKN87_RS02510	COG0393	Putative heavy-metal-binding
AKN87_RS02520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AKN87_RS02545	COG1024	Enoyl-CoA hydratase
AKN87_RS02560	COG2204	response regulator
AKN87_RS02565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKN87_RS02565	COG4191	Histidine kinase
AKN87_RS02595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKN87_RS02600	COG0481	GTPase activity
AKN87_RS02610	COG0571	ribonuclease III activity
AKN87_RS02615	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AKN87_RS02620	COG1381	Involved in DNA repair and RecF pathway recombination
AKN87_RS02625	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AKN87_RS02645	COG1131	(ABC) transporter
AKN87_RS02650	COG0842	Transport permease protein
AKN87_RS02655	COG0791	NLP P60 protein
AKN87_RS02660	COG0791	NLP P60 protein
AKN87_RS02665	COG0133	tryptophan synthase activity
AKN87_RS02675	COG0642	Histidine kinase
AKN87_RS02685	COG0745	RESPONSE REGULATOR receiver
AKN87_RS02690	COG2350	Protein conserved in bacteria
AKN87_RS02695	COG2917	probably involved in intracellular septation
AKN87_RS02700	COG0613	PHP domain protein
AKN87_RS02705	COG0009	L-threonylcarbamoyladenylate synthase
AKN87_RS02710	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AKN87_RS02715	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AKN87_RS02725	COG0535	radical SAM domain protein
AKN87_RS02735	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AKN87_RS02810	COG1397	ADP-ribosylglycohydrolase
AKN87_RS02815	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AKN87_RS02825	COG0419	ATPase involved in DNA repair
AKN87_RS02830	COG0420	3'-5' exonuclease activity
AKN87_RS02840	COG0628	permease
AKN87_RS02850	COG0625	glutathione transferase activity
AKN87_RS02870	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AKN87_RS02875	COG0784	Response regulator, receiver
AKN87_RS02875	COG5002	protein histidine kinase activity
AKN87_RS02875	COG2205	protein histidine kinase activity
AKN87_RS02880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AKN87_RS02890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKN87_RS02895	COG2814	Major facilitator Superfamily
AKN87_RS02915	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AKN87_RS02920	COG0585	pseudouridine synthase activity
AKN87_RS02925	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AKN87_RS02935	COG2911	Protein conserved in bacteria
AKN87_RS02940	COG0729	surface antigen
AKN87_RS02945	COG0708	Exodeoxyribonuclease III
AKN87_RS02950	COG3781	membrane
AKN87_RS02955	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AKN87_RS02960	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AKN87_RS03175	COG2801	Transposase and inactivated derivatives
AKN87_RS03180	COG2963	transposase activity
AKN87_RS03210	COG0037	tRNA processing
AKN87_RS03230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AKN87_RS03240	COG0560	Phosphoserine phosphatase
AKN87_RS03260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKN87_RS03275	COG4953	penicillin-binding protein 1C
AKN87_RS03285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AKN87_RS03290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AKN87_RS03295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AKN87_RS03300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AKN87_RS03305	COG5007	Belongs to the BolA IbaG family
AKN87_RS03325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AKN87_RS03330	COG1127	ABC transporter
AKN87_RS03340	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AKN87_RS03350	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AKN87_RS03355	COG1137	ATPase activity
AKN87_RS03370	COG1132	(ABC) transporter
AKN87_RS03395	COG0730	response to heat
AKN87_RS03410	COG1024	Enoyl-CoA hydratase
AKN87_RS03415	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AKN87_RS03425	COG2010	Cytochrome c
AKN87_RS03430	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AKN87_RS03430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKN87_RS03435	COG0023	Translation Initiation Factor
AKN87_RS03440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKN87_RS03445	COG0069	glutamate synthase activity
AKN87_RS03450	COG2119	membrane
AKN87_RS03455	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AKN87_RS03460	COG0675	Transposase, IS605 OrfB family
AKN87_RS03485	COG1335	isochorismatase
AKN87_RS03545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AKN87_RS03550	COG2373	Large extracellular alpha-helical protein
AKN87_RS03565	COG0433	COG0433 Predicted ATPase
AKN87_RS03570	COG0788	formyltetrahydrofolate deformylase activity
AKN87_RS03575	COG2853	Lipoprotein
AKN87_RS03580	COG0215	cysteine-tRNA ligase activity
AKN87_RS03585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKN87_RS03590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AKN87_RS03595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKN87_RS03600	COG2031	fatty acid transporter
AKN87_RS03605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AKN87_RS03610	COG3115	cell septum assembly
AKN87_RS03615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AKN87_RS03620	COG2824	Alkylphosphonate utilization operon protein PhnA
AKN87_RS03630	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AKN87_RS03635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AKN87_RS03640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AKN87_RS03645	COG1605	Chorismate mutase
AKN87_RS03645	COG0077	Prephenate dehydratase
AKN87_RS03660	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AKN87_RS03665	COG1132	(ABC) transporter
AKN87_RS03675	COG0628	permease
AKN87_RS03685	COG0271	Belongs to the BolA IbaG family
AKN87_RS03715	COG0848	biopolymer transport protein
AKN87_RS03720	COG0811	peptide transport
AKN87_RS03725	COG0811	peptide transport
AKN87_RS03735	COG0121	glutamine amidotransferase
AKN87_RS03745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AKN87_RS03765	COG3344	reverse transcriptase
AKN87_RS03770	COG3344	reverse transcriptase
AKN87_RS03795	COG0730	response to heat
AKN87_RS03800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AKN87_RS03805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AKN87_RS03815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AKN87_RS03820	COG4208	sulfate ABC transporter
AKN87_RS03830	COG0469	pyruvate kinase activity
AKN87_RS03835	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AKN87_RS03840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AKN87_RS03845	COG3842	ATPase activity
AKN87_RS03865	COG2885	chlorophyll binding
AKN87_RS03875	COG0427	acetyl-CoA hydrolase
AKN87_RS03900	COG0513	Belongs to the DEAD box helicase family
AKN87_RS03915	COG2212	antiporter activity
AKN87_RS03925	COG0651	ATP synthesis coupled electron transport
AKN87_RS03930	COG1006	Multisubunit Na H antiporter MnhC subunit
AKN87_RS03935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AKN87_RS03935	COG2111	Na H antiporter
AKN87_RS03940	COG0604	alcohol dehydrogenase
AKN87_RS03955	COG0556	nucleotide-excision repair
AKN87_RS03965	COG1136	(ABC) transporter
AKN87_RS03980	COG2996	Protein conserved in bacteria
AKN87_RS03990	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKN87_RS03995	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKN87_RS04000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AKN87_RS04005	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKN87_RS04015	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AKN87_RS04025	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AKN87_RS04035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AKN87_RS04040	COG0233	cytoplasmic translational termination
AKN87_RS04045	COG0528	UMP kinase activity
AKN87_RS04050	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AKN87_RS04055	COG0052	Belongs to the universal ribosomal protein uS2 family
AKN87_RS04060	COG0024	Methionine aminopeptidase
AKN87_RS04065	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AKN87_RS04070	COG1393	Belongs to the ArsC family
AKN87_RS04075	COG2171	N-acyltransferase activity
AKN87_RS04080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AKN87_RS04085	COG2166	iron-sulfur cluster assembly
AKN87_RS04120	COG2814	Major facilitator Superfamily
AKN87_RS04130	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AKN87_RS04135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AKN87_RS04145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AKN87_RS04150	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AKN87_RS04160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AKN87_RS04165	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AKN87_RS04180	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AKN87_RS04195	COG0604	alcohol dehydrogenase
AKN87_RS04200	COG0616	signal peptide processing
AKN87_RS04225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AKN87_RS04230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AKN87_RS04235	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AKN87_RS04240	COG2835	tetraacyldisaccharide 4'-kinase activity
AKN87_RS04245	COG1663	tetraacyldisaccharide 4'-kinase activity
AKN87_RS04250	COG2333	competence protein COMEC
AKN87_RS04250	COG0658	competence protein
AKN87_RS04260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AKN87_RS04270	COG5016	pyruvate
AKN87_RS04270	COG0511	ligase activity, forming carbon-carbon bonds
AKN87_RS04280	COG2239	Acts as a magnesium transporter
AKN87_RS04310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AKN87_RS04320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AKN87_RS04330	COG0037	tRNA processing
AKN87_RS04335	COG2814	Major facilitator Superfamily
AKN87_RS04340	COG0284	orotidine-5'-phosphate decarboxylase activity
AKN87_RS04345	COG0114	fumarate hydratase activity
AKN87_RS04375	COG1862	Preprotein translocase
AKN87_RS04385	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AKN87_RS04395	COG2259	Doxx family
AKN87_RS04400	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AKN87_RS04405	COG2366	antibiotic biosynthetic process
AKN87_RS04410	COG2885	chlorophyll binding
AKN87_RS04425	COG0400	carboxylic ester hydrolase activity
AKN87_RS04430	COG0513	Belongs to the DEAD box helicase family
AKN87_RS04435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AKN87_RS04445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AKN87_RS04455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKN87_RS04460	COG0425	Belongs to the sulfur carrier protein TusA family
AKN87_RS04465	COG4783	chaperone-mediated protein folding
AKN87_RS04475	COG2814	Major facilitator Superfamily
AKN87_RS04480	COG2356	endonuclease I
AKN87_RS04490	COG1272	protein, Hemolysin III
AKN87_RS04505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AKN87_RS04510	COG0492	ferredoxin-NADP+ reductase activity
AKN87_RS04515	COG0456	acetyltransferase
AKN87_RS04535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AKN87_RS04540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKN87_RS04545	COG1120	ATPase activity
AKN87_RS04555	COG1492	cobalamin metabolic process
AKN87_RS04560	COG0778	Nitroreductase
AKN87_RS04595	COG0583	DNA-binding transcription factor activity
AKN87_RS04635	COG0318	PFAM AMP-dependent synthetase and ligase
AKN87_RS04640	COG1960	acyl-CoA dehydrogenase activity
AKN87_RS04645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AKN87_RS04650	COG1250	3-hydroxyacyl-CoA dehydrogenase
AKN87_RS04650	COG1024	Enoyl-CoA hydratase
AKN87_RS04675	COG0789	Transcriptional regulator
AKN87_RS04680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AKN87_RS04705	COG0045	succinate-CoA ligase (ADP-forming) activity
AKN87_RS04725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AKN87_RS04740	COG2009	succinate dehydrogenase
AKN87_RS04760	COG2084	Dehydrogenase
AKN87_RS04770	COG3278	Belongs to the heme-copper respiratory oxidase family
AKN87_RS04785	COG2010	Cytochrome c
AKN87_RS04800	COG2217	Heavy metal translocating P-type atpase
AKN87_RS04820	COG0741	lytic transglycosylase activity
AKN87_RS04825	COG2175	clavaminate synthase activity
AKN87_RS04830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AKN87_RS04835	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AKN87_RS04840	COG4521	taurine ABC transporter
AKN87_RS04845	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AKN87_RS04850	COG0492	ferredoxin-NADP+ reductase activity
AKN87_RS04870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AKN87_RS04890	COG0776	regulation of translation
AKN87_RS04895	COG0316	Belongs to the HesB IscA family
AKN87_RS04895	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AKN87_RS04900	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AKN87_RS04920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AKN87_RS04925	COG2840	Smr protein MutS2
AKN87_RS04955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AKN87_RS04960	COG0018	arginyl-trna synthetase
AKN87_RS04975	COG4206	TonB-dependent receptor
AKN87_RS04985	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AKN87_RS04995	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AKN87_RS05005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AKN87_RS05005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AKN87_RS05010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AKN87_RS05020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AKN87_RS05030	COG1070	Carbohydrate kinase
AKN87_RS05035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AKN87_RS05045	COG2207	Transcriptional regulator
AKN87_RS05080	COG0183	Belongs to the thiolase family
AKN87_RS05085	COG1024	Enoyl-CoA hydratase
AKN87_RS05085	COG1250	3-hydroxyacyl-CoA dehydrogenase
AKN87_RS05090	COG0589	response to stress
AKN87_RS05095	COG0405	Gamma-glutamyltransferase
AKN87_RS05100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AKN87_RS05105	COG0488	(ABC) transporter
AKN87_RS05120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AKN87_RS05125	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AKN87_RS05135	COG1388	LysM domain
AKN87_RS05135	COG0741	lytic transglycosylase activity
AKN87_RS05145	COG4166	transmembrane transport
AKN87_RS05150	COG4174	ABC transporter (Permease)
AKN87_RS05155	COG4239	(ABC) transporter, permease
AKN87_RS05160	COG4172	Belongs to the ABC transporter superfamily
AKN87_RS05180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AKN87_RS05205	COG0753	catalase activity
AKN87_RS05210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AKN87_RS05215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AKN87_RS05220	COG0482	sulfurtransferase activity
AKN87_RS05225	COG2915	High frequency lysogenization protein hflD homolog
AKN87_RS05230	COG0697	spore germination
AKN87_RS05240	COG2850	peptidyl-arginine hydroxylation
AKN87_RS05245	COG2153	protein acetylation
AKN87_RS05265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AKN87_RS05275	COG2226	methyltransferase
AKN87_RS05290	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AKN87_RS05295	COG0519	Catalyzes the synthesis of GMP from XMP
AKN87_RS05295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AKN87_RS05305	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AKN87_RS05310	COG2860	membrane
AKN87_RS05315	COG0644	oxidoreductase
AKN87_RS05350	COG1404	Belongs to the peptidase S8 family
AKN87_RS05355	COG1132	(ABC) transporter
AKN87_RS05360	COG3284	Transcriptional regulator
AKN87_RS05395	COG0435	Glutathione S-transferase
AKN87_RS05405	COG1522	sequence-specific DNA binding
AKN87_RS05415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AKN87_RS05425	COG1294	oxidase, subunit
AKN87_RS05435	COG3162	membrane
AKN87_RS05440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKN87_RS05445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AKN87_RS05450	COG1570	exodeoxyribonuclease VII activity
AKN87_RS05455	COG4942	peptidase
AKN87_RS05460	COG0668	transmembrane transport
AKN87_RS05475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AKN87_RS05480	COG2900	Belongs to the SlyX family
AKN87_RS05495	COG0442	prolyl-tRNA aminoacylation
AKN87_RS05500	COG0786	glutamate:sodium symporter activity
AKN87_RS05510	COG1024	Enoyl-CoA hydratase
AKN87_RS05515	COG0183	Belongs to the thiolase family
AKN87_RS05525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AKN87_RS05535	COG0583	DNA-binding transcription factor activity
AKN87_RS05550	COG1024	Enoyl-CoA hydratase
AKN87_RS05555	COG1960	acyl-CoA dehydrogenase activity
AKN87_RS05560	COG0459	protein refolding
AKN87_RS05565	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AKN87_RS05570	COG3030	protein affecting phage T7 exclusion by the F plasmid
AKN87_RS05575	COG2211	Major facilitator Superfamily
AKN87_RS05665	COG0582	viral genome integration into host DNA
AKN87_RS05680	COG2969	positive regulation of protein catabolic process
AKN87_RS05685	COG0625	glutathione transferase activity
AKN87_RS05690	COG2857	Cytochrome c1
AKN87_RS05695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AKN87_RS05700	COG0723	plastoquinol--plastocyanin reductase activity
AKN87_RS05705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AKN87_RS05710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AKN87_RS05715	COG0659	secondary active sulfate transmembrane transporter activity
AKN87_RS05720	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AKN87_RS05725	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AKN87_RS05735	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AKN87_RS05740	COG1538	Outer membrane efflux protein
AKN87_RS05745	COG1702	phosphate starvation-inducible protein PhoH
AKN87_RS05760	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AKN87_RS05780	COG1011	Hydrolase
AKN87_RS05795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AKN87_RS05810	COG1965	Belongs to the frataxin family
AKN87_RS05815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AKN87_RS05820	COG3118	belongs to the thioredoxin family
AKN87_RS05830	COG0617	tRNA 3'-terminal CCA addition
AKN87_RS05840	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AKN87_RS05845	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AKN87_RS05855	COG0166	Belongs to the GPI family
AKN87_RS05875	COG1362	aminopeptidase activity
AKN87_RS05880	COG1671	Belongs to the UPF0178 family
AKN87_RS05890	COG0436	Aminotransferase
AKN87_RS05900	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AKN87_RS05915	COG0545	Peptidyl-prolyl cis-trans isomerase
AKN87_RS05925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AKN87_RS05945	COG0860	N-Acetylmuramoyl-L-alanine amidase
AKN87_RS05950	COG0802	atpase or kinase
AKN87_RS05960	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AKN87_RS05965	COG1162	GTPase activity
AKN87_RS05970	COG0688	phosphatidylethanolamine metabolic process
AKN87_RS05995	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AKN87_RS06005	COG2226	methyltransferase
AKN87_RS06015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AKN87_RS06020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AKN87_RS06030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AKN87_RS06035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AKN87_RS06050	COG0789	Transcriptional regulator
AKN87_RS06060	COG1067	ATP-dependent peptidase activity
AKN87_RS06075	COG1136	(ABC) transporter
AKN87_RS06090	COG0778	Nitroreductase
AKN87_RS06095	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AKN87_RS06100	COG0534	Mate efflux family protein
AKN87_RS06105	COG3118	belongs to the thioredoxin family
AKN87_RS06110	COG2813	Specifically methylates the guanine in position
AKN87_RS06120	COG3313	Fe-S protein
AKN87_RS06125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKN87_RS06130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKN87_RS06135	COG0633	Ferredoxin
AKN87_RS06145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AKN87_RS06150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AKN87_RS06150	COG0604	alcohol dehydrogenase
AKN87_RS06150	COG4221	oxidoreductase activity
AKN87_RS06150	COG3321	synthase
AKN87_RS06155	COG0793	Belongs to the peptidase S41A family
AKN87_RS06175	COG0545	Peptidyl-prolyl cis-trans isomerase
AKN87_RS06200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AKN87_RS06210	COG0330	HflC and HflK could
AKN87_RS06215	COG0330	HflC and HflK could
AKN87_RS06220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AKN87_RS06225	COG1923	regulation of RNA biosynthetic process
AKN87_RS06245	COG1028	Short-chain dehydrogenase reductase Sdr
AKN87_RS06250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AKN87_RS06250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AKN87_RS06255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AKN87_RS06260	COG3258	Cytochrome c
AKN87_RS06270	COG0814	amino acid
AKN87_RS06275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AKN87_RS06280	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AKN87_RS06310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AKN87_RS06315	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKN87_RS06320	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AKN87_RS06325	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AKN87_RS06330	COG0142	geranyltranstransferase activity
AKN87_RS06335	COG1970	mechanosensitive ion channel activity
AKN87_RS06340	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AKN87_RS06350	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AKN87_RS06355	COG2885	chlorophyll binding
AKN87_RS06380	COG0824	Thioesterase
AKN87_RS06385	COG2255	four-way junction helicase activity
AKN87_RS06390	COG0632	four-way junction helicase activity
AKN87_RS06395	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AKN87_RS06405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AKN87_RS06415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AKN87_RS06425	COG0525	valine-tRNA ligase activity
AKN87_RS06435	COG4120	Belongs to the binding-protein-dependent transport system permease family
AKN87_RS06440	COG1122	ATPase activity
AKN87_RS06445	COG0471	metal ion transport
AKN87_RS06445	COG0490	domain, Protein
AKN87_RS06450	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AKN87_RS06460	COG0237	dephospho-CoA kinase activity
AKN87_RS06465	COG0134	indole-3-glycerol-phosphate synthase activity
AKN87_RS06470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AKN87_RS06490	COG0546	phosphoglycolate phosphatase activity
AKN87_RS06495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AKN87_RS06525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AKN87_RS06530	COG0456	acetyltransferase
AKN87_RS06540	COG1722	exodeoxyribonuclease VII activity
AKN87_RS06545	COG0142	geranyltranstransferase activity
AKN87_RS06570	COG3530	Putative quorum-sensing-regulated virulence factor
AKN87_RS06575	COG0513	Belongs to the DEAD box helicase family
AKN87_RS06580	COG1509	lysine 2,3-aminomutase activity
AKN87_RS06585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AKN87_RS06605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AKN87_RS06625	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AKN87_RS06635	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AKN87_RS06640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AKN87_RS06645	COG3178	'Phosphotransferase
AKN87_RS06650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AKN87_RS06655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AKN87_RS06660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AKN87_RS06670	COG0842	Transport permease protein
AKN87_RS06675	COG0842	Transport permease protein
AKN87_RS06675	COG1129	ABC transporter
AKN87_RS06680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKN87_RS06685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AKN87_RS06700	COG3079	Belongs to the UPF0149 family
AKN87_RS06705	COG0006	proline dipeptidase activity
AKN87_RS06710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AKN87_RS06720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AKN87_RS06745	COG0560	Phosphoserine phosphatase
AKN87_RS06745	COG3830	Belongs to the UPF0237 family
AKN87_RS06755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AKN87_RS06755	COG3008	intermembrane lipid transfer
AKN87_RS06765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AKN87_RS06785	COG3150	esterase
AKN87_RS06815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AKN87_RS06825	COG0204	Acyl-transferase
AKN87_RS06840	COG3098	single-species biofilm formation
AKN87_RS06850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AKN87_RS06860	COG0494	nUDIX hydrolase
AKN87_RS06870	COG1217	gtp-binding protein TYPA
AKN87_RS06875	COG0301	tRNA thio-modification
AKN87_RS06875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKN87_RS06890	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AKN87_RS06895	COG1012	belongs to the aldehyde dehydrogenase family
AKN87_RS06900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AKN87_RS06905	COG0704	Plays a role in the regulation of phosphate uptake
AKN87_RS06910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AKN87_RS06915	COG0581	inorganic phosphate transmembrane transporter activity
AKN87_RS06935	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AKN87_RS06940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AKN87_RS06945	COG2963	transposase activity
AKN87_RS06965	COG0281	malic enzyme
AKN87_RS06970	COG0254	rRNA binding
AKN87_RS06975	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AKN87_RS07005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKN87_RS07010	COG2274	protein secretion by the type I secretion system
AKN87_RS07030	COG0427	acetyl-CoA hydrolase
AKN87_RS07045	COG1752	Esterase of the alpha-beta hydrolase superfamily
AKN87_RS07050	COG1192	Involved in chromosome partitioning
AKN87_RS07055	COG0305	Participates in initiation and elongation during chromosome replication
AKN87_RS07120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AKN87_RS07125	COG1595	DNA-templated transcription, initiation
AKN87_RS07135	COG4771	TonB-dependent receptor
AKN87_RS07300	COG2814	Major facilitator Superfamily
AKN87_RS07310	COG3177	Filamentation induced by cAMP protein fic
AKN87_RS07315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AKN87_RS07385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AKN87_RS07435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AKN87_RS07505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKN87_RS07515	COG0179	Fumarylacetoacetate (FAA) hydrolase
AKN87_RS07520	COG0277	FAD linked oxidase domain protein
AKN87_RS07525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AKN87_RS07535	COG2814	Major facilitator Superfamily
AKN87_RS07545	COG0753	catalase activity
AKN87_RS07555	COG0523	cobalamin synthesis protein
AKN87_RS07580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKN87_RS07585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKN87_RS07595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AKN87_RS07600	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AKN87_RS07605	COG2003	Belongs to the UPF0758 family
AKN87_RS07610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AKN87_RS07615	COG0756	dUTP diphosphatase activity
AKN87_RS07625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AKN87_RS07645	COG1160	GTP binding
AKN87_RS07670	COG0494	nUDIX hydrolase
AKN87_RS07680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AKN87_RS07690	COG1960	acyl-CoA dehydrogenase activity
AKN87_RS07715	COG1120	ATPase activity
AKN87_RS07720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKN87_RS07725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKN87_RS07730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AKN87_RS07745	COG2855	membrane
AKN87_RS07755	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AKN87_RS07755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AKN87_RS07765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AKN87_RS07770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AKN87_RS07775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKN87_RS07805	COG0730	response to heat
AKN87_RS07815	COG1414	Transcriptional regulator
AKN87_RS07825	COG4771	TonB-dependent receptor
AKN87_RS07835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKN87_RS07845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKN87_RS07860	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AKN87_RS07860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AKN87_RS07870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AKN87_RS07880	COG1979	alcohol dehydrogenase
AKN87_RS07885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AKN87_RS07890	COG0583	DNA-binding transcription factor activity
AKN87_RS07905	COG0814	amino acid
AKN87_RS07910	COG1368	sulfuric ester hydrolase activity
AKN87_RS07925	COG4149	molybdate abc transporter
AKN87_RS07930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AKN87_RS07945	COG1177	transmembrane transport
AKN87_RS07950	COG1176	ABC-type spermidine putrescine transport system, permease component I
AKN87_RS07955	COG3842	ATPase activity
AKN87_RS07970	COG3909	cytochrome
AKN87_RS07975	COG1652	LysM domain
AKN87_RS08000	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AKN87_RS08010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AKN87_RS08015	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AKN87_RS08025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKN87_RS08030	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AKN87_RS08035	COG4942	peptidase
AKN87_RS08040	COG0793	Belongs to the peptidase S41A family
AKN87_RS08065	COG0131	Imidazoleglycerol-phosphate dehydratase
AKN87_RS08080	COG1194	a g-specific adenine glycosylase
AKN87_RS08085	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AKN87_RS08100	COG1858	cytochrome C peroxidase
AKN87_RS08115	COG2353	YceI-like domain
AKN87_RS08120	COG3038	cytochrome b561
AKN87_RS08125	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AKN87_RS08130	COG2193	ferroxidase activity
AKN87_RS08140	COG0126	phosphoglycerate kinase activity
AKN87_RS08145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AKN87_RS08155	COG1040	competence protein
AKN87_RS08160	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AKN87_RS08165	COG0156	8-amino-7-oxononanoate synthase activity
AKN87_RS08170	COG2226	methyltransferase
AKN87_RS08170	COG1073	alpha beta
AKN87_RS08190	COG0303	'Molybdopterin
AKN87_RS08195	COG0521	Mo-molybdopterin cofactor biosynthetic process
AKN87_RS08225	COG1561	YicC-like family, N-terminal region
AKN87_RS08230	COG4628	conserved protein (DUF2132)
AKN87_RS08235	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AKN87_RS08265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AKN87_RS08275	COG0826	peptidase U32
AKN87_RS08285	COG0318	PFAM AMP-dependent synthetase and ligase
AKN87_RS08305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AKN87_RS08310	COG0569	domain protein
AKN87_RS08315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AKN87_RS08320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AKN87_RS08325	COG0242	peptide deformylase activity
AKN87_RS08335	COG0758	DNA mediated transformation
AKN87_RS08340	COG0009	L-threonylcarbamoyladenylate synthase
AKN87_RS08350	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AKN87_RS08355	COG2239	Acts as a magnesium transporter
AKN87_RS08360	COG1285	pathogenesis
AKN87_RS08375	COG1966	Carbon starvation protein
AKN87_RS08400	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AKN87_RS08405	COG0730	response to heat
AKN87_RS08410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AKN87_RS08415	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AKN87_RS08435	COG3154	lipid carrier protein
AKN87_RS08440	COG0826	peptidase U32
AKN87_RS08445	COG0826	peptidase U32
AKN87_RS08450	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AKN87_RS08465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AKN87_RS08480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AKN87_RS08485	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AKN87_RS08490	COG0252	asparaginase activity
AKN87_RS08520	COG1132	(ABC) transporter
AKN87_RS08525	COG0617	tRNA 3'-terminal CCA addition
AKN87_RS08525	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AKN87_RS08525	COG3620	sequence-specific DNA binding
AKN87_RS08535	COG0789	Transcriptional regulator
AKN87_RS08570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AKN87_RS08575	COG0129	dihydroxy-acid dehydratase activity
AKN87_RS08590	COG3135	benzoate transporter
AKN87_RS08595	COG1178	ABC-type Fe3 transport system permease component
AKN87_RS08600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AKN87_RS08610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AKN87_RS08610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AKN87_RS08620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AKN87_RS08635	COG0742	ribosomal rna small subunit methyltransferase
AKN87_RS08640	COG0612	Peptidase, M16
AKN87_RS08645	COG0612	Peptidase, M16
AKN87_RS08655	COG0552	protein localization to endoplasmic reticulum
AKN87_RS08660	COG2884	Cell division ATP-binding protein ftsE
AKN87_RS08665	COG2177	Part of the ABC transporter FtsEX involved in
AKN87_RS08675	COG2431	L-lysine efflux transmembrane transporter activity
AKN87_RS08680	COG0833	amino acid
AKN87_RS08690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AKN87_RS08695	COG0513	Belongs to the DEAD box helicase family
AKN87_RS08700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AKN87_RS08705	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AKN87_RS08760	COG0700	Nucleoside recognition
AKN87_RS08765	COG3023	N-Acetylmuramoyl-L-alanine amidase
AKN87_RS08775	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AKN87_RS08780	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AKN87_RS08785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AKN87_RS08790	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AKN87_RS08795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AKN87_RS08800	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKN87_RS08805	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AKN87_RS08815	COG0356	it plays a direct role in the translocation of protons across the membrane
AKN87_RS08825	COG1475	DNA binding
AKN87_RS08830	COG1192	Involved in chromosome partitioning
AKN87_RS08845	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AKN87_RS08855	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AKN87_RS08860	COG0594	ribonuclease P activity
AKN87_RS08865	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AKN87_RS08900	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AKN87_RS08915	COG1758	RNA polymerase activity
AKN87_RS08920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AKN87_RS08940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AKN87_RS08945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AKN87_RS08950	COG2363	Small membrane protein
AKN87_RS08960	COG2022	thiamine diphosphate biosynthetic process
AKN87_RS08965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AKN87_RS08985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AKN87_RS08990	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AKN87_RS09005	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AKN87_RS09020	COG0248	Ppx GppA phosphatase
AKN87_RS09030	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AKN87_RS09035	COG0592	DNA-directed DNA polymerase activity
AKN87_RS09040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AKN87_RS09050	COG0642	Histidine kinase
AKN87_RS09065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AKN87_RS09075	COG0159	tryptophan synthase activity
AKN87_RS09080	COG0133	tryptophan synthase activity
AKN87_RS09090	COG1960	acyl-CoA dehydrogenase activity
AKN87_RS09095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AKN87_RS09100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AKN87_RS09105	COG0583	DNA-binding transcription factor activity
AKN87_RS09110	COG3384	dioxygenase
AKN87_RS09120	COG3038	cytochrome b561
AKN87_RS09125	COG1289	transmembrane transporter activity
AKN87_RS09130	COG1944	ATP diphosphatase activity
AKN87_RS09135	COG2207	Transcriptional regulator
AKN87_RS09145	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AKN87_RS09155	COG0303	'Molybdopterin
AKN87_RS09160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AKN87_RS09170	COG0642	Histidine kinase
AKN87_RS09180	COG1368	sulfuric ester hydrolase activity
AKN87_RS09210	COG0084	hydrolase, TatD family'
AKN87_RS09220	COG1451	nucleotide metabolic process
AKN87_RS09225	COG0071	Belongs to the small heat shock protein (HSP20) family
AKN87_RS09245	COG0175	sulfate reduction
AKN87_RS09250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AKN87_RS09250	COG1648	precorrin-2 dehydrogenase activity
AKN87_RS09260	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AKN87_RS09265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AKN87_RS09270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AKN87_RS09275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AKN87_RS09290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AKN87_RS09300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AKN87_RS09315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AKN87_RS09325	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AKN87_RS09330	COG0215	cysteine-tRNA ligase activity
AKN87_RS09340	COG1469	GTP cyclohydrolase I activity
AKN87_RS09345	COG0523	cobalamin synthesis protein
AKN87_RS09370	COG0306	phosphate transporter
AKN87_RS09375	COG1392	Phosphate transport regulator
AKN87_RS09385	COG0330	HflC and HflK could
AKN87_RS09420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AKN87_RS09430	COG0540	Belongs to the ATCase OTCase family
AKN87_RS09440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AKN87_RS09445	COG3204	pilus organization
AKN87_RS09455	COG0494	nUDIX hydrolase
AKN87_RS09460	COG1011	Hydrolase
AKN87_RS09490	COG1872	DUF167
AKN87_RS09495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AKN87_RS09500	COG2813	Specifically methylates the guanine in position
AKN87_RS09500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AKN87_RS09515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AKN87_RS09530	COG0583	DNA-binding transcription factor activity
AKN87_RS09535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AKN87_RS09550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AKN87_RS09570	COG0751	glycine-tRNA ligase activity
AKN87_RS09575	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AKN87_RS09595	COG0347	Belongs to the P(II) protein family
AKN87_RS09610	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AKN87_RS09615	COG3161	chorismate lyase activity
AKN87_RS09630	COG3258	Cytochrome c
AKN87_RS09635	COG2863	cytochrome
AKN87_RS09640	COG0606	chelatase, subunit chli
AKN87_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
AKN87_RS09655	COG1028	Short-chain dehydrogenase reductase Sdr
AKN87_RS09660	COG0019	diaminopimelate decarboxylase activity
AKN87_RS09685	COG4771	TonB-dependent receptor
AKN87_RS09695	COG4191	Histidine kinase
AKN87_RS09700	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AKN87_RS09705	COG1519	Transferase
AKN87_RS09715	COG0501	Belongs to the peptidase M48B family
AKN87_RS09725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AKN87_RS09730	COG3047	cAMP biosynthetic process
AKN87_RS09735	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AKN87_RS09740	COG1490	D-aminoacyl-tRNA deacylase activity
AKN87_RS09745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AKN87_RS09750	COG0488	(ABC) transporter
AKN87_RS09760	COG2918	glutathione biosynthetic process
AKN87_RS09765	COG2183	response to ionizing radiation
AKN87_RS09780	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AKN87_RS09785	COG0735	belongs to the Fur family
AKN87_RS09790	COG1121	(ABC) transporter
AKN87_RS09795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AKN87_RS09810	COG2011	ABC-type metal ion transport system permease component
AKN87_RS09820	COG1765	OsmC-like protein
AKN87_RS09825	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AKN87_RS09830	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AKN87_RS09835	COG0537	adenosine 5'-monophosphoramidase activity
AKN87_RS09840	COG1981	membrane
AKN87_RS09845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AKN87_RS09850	COG0316	Belongs to the HesB IscA family
AKN87_RS09855	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AKN87_RS09860	COG0739	heme binding
AKN87_RS09865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AKN87_RS09895	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AKN87_RS09895	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AKN87_RS09900	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AKN87_RS09925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AKN87_RS09945	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AKN87_RS09950	COG0081	regulation of translation
AKN87_RS09955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AKN87_RS09960	COG0222	ribosome binding
AKN87_RS09965	COG0085	RNA polymerase activity
AKN87_RS09975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AKN87_RS09980	COG0049	tRNA binding
AKN87_RS09985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AKN87_RS09990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AKN87_RS09995	COG0051	transcription antitermination factor activity, RNA binding
AKN87_RS10000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AKN87_RS10005	COG0088	Forms part of the polypeptide exit tunnel
AKN87_RS10015	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AKN87_RS10020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AKN87_RS10025	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AKN87_RS10030	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AKN87_RS10040	COG0255	Belongs to the universal ribosomal protein uL29 family
AKN87_RS10045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AKN87_RS10050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AKN87_RS10055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AKN87_RS10065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AKN87_RS10070	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AKN87_RS10075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AKN87_RS10080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AKN87_RS10085	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AKN87_RS10090	COG1841	ribosomal large subunit assembly
AKN87_RS10095	COG0200	Binds to the 23S rRNA
AKN87_RS10110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AKN87_RS10115	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AKN87_RS10120	COG0202	RNA polymerase activity
AKN87_RS10125	COG0203	ribosomal protein L17
AKN87_RS10135	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AKN87_RS10155	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AKN87_RS10165	COG2081	HI0933 family
AKN87_RS10175	COG3263	regulation of cellular component size
AKN87_RS10180	COG1196	nuclear chromosome segregation
AKN87_RS10180	COG3264	Mechanosensitive ion channel
AKN87_RS10185	COG0676	glucose-6-phosphate 1-epimerase activity
AKN87_RS10210	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AKN87_RS10215	COG2176	DNA-directed DNA polymerase activity
AKN87_RS10225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AKN87_RS10250	COG0697	spore germination
AKN87_RS10255	COG1917	Cupin 2, conserved barrel domain protein
AKN87_RS10255	COG2207	Transcriptional regulator
AKN87_RS10260	COG0113	porphobilinogen synthase activity
AKN87_RS10265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AKN87_RS10280	COG1960	acyl-CoA dehydrogenase activity
AKN87_RS10290	COG0318	PFAM AMP-dependent synthetase and ligase
AKN87_RS10295	COG4191	Histidine kinase
AKN87_RS10300	COG4566	intracellular signal transduction
AKN87_RS10305	COG0617	tRNA 3'-terminal CCA addition
AKN87_RS10330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AKN87_RS10345	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AKN87_RS10350	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AKN87_RS10355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AKN87_RS10370	COG1346	cytolysis
AKN87_RS10375	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AKN87_RS10375	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AKN87_RS10380	COG4989	oxidoreductase activity
AKN87_RS10390	COG1301	dicarboxylic acid transport
AKN87_RS10405	COG4659	FMN binding
AKN87_RS10410	COG4658	electron transport chain
AKN87_RS10420	COG2878	Part of a membrane complex involved in electron transport
AKN87_RS10425	COG4657	Part of a membrane complex involved in electron transport
AKN87_RS10435	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKN87_RS10455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AKN87_RS10460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AKN87_RS10470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AKN87_RS10475	COG0501	Belongs to the peptidase M48B family
AKN87_RS10485	COG1643	Atp-dependent helicase
AKN87_RS10510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AKN87_RS10515	COG1802	Transcriptional regulator
AKN87_RS10525	COG0372	Belongs to the citrate synthase family
AKN87_RS10530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AKN87_RS10540	COG2264	protein methyltransferase activity
AKN87_RS10550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKN87_RS10560	COG0318	PFAM AMP-dependent synthetase and ligase
AKN87_RS10565	COG0183	Belongs to the thiolase family
AKN87_RS10580	COG3148	PFAM DTW domain containing protein
AKN87_RS10595	COG2873	o-acetylhomoserine
AKN87_RS10605	COG1690	Belongs to the RtcB family
AKN87_RS10610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AKN87_RS10625	COG0288	reversible hydration of carbon dioxide
AKN87_RS10640	COG0022	dehydrogenase e1 component
AKN87_RS10645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AKN87_RS10665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AKN87_RS10675	COG1028	Short-chain dehydrogenase reductase Sdr
AKN87_RS10680	COG0671	phosphoesterase, PA-phosphatase related
AKN87_RS10685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AKN87_RS10690	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AKN87_RS10695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AKN87_RS10705	COG1607	acyl-coa hydrolase
AKN87_RS10715	COG0861	Integral membrane protein TerC family
AKN87_RS10725	COG0488	(ABC) transporter
AKN87_RS10750	COG0181	hydroxymethylbilane synthase activity
AKN87_RS10775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKN87_RS10780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AKN87_RS10785	COG3956	TIGRFAM MazG family protein
AKN87_RS10790	COG3122	Protein conserved in bacteria
AKN87_RS10800	COG3258	Cytochrome c
AKN87_RS10805	COG0268	Binds directly to 16S ribosomal RNA
AKN87_RS10810	COG0728	peptidoglycan biosynthetic process
AKN87_RS10815	COG0196	riboflavin kinase activity
AKN87_RS10820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AKN87_RS10830	COG1047	Peptidyl-prolyl cis-trans
AKN87_RS10835	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AKN87_RS10850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AKN87_RS10865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AKN87_RS10890	COG4574	serine-type endopeptidase inhibitor activity
AKN87_RS10900	COG0322	excinuclease ABC activity
AKN87_RS10915	COG3100	YcgL domain-containing protein
AKN87_RS10925	COG0675	Transposase, IS605 OrfB family
AKN87_RS10945	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AKN87_RS10950	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AKN87_RS10960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKN87_RS10990	COG0714	Associated with various cellular activities
AKN87_RS10995	COG0564	pseudouridine synthase activity
AKN87_RS11000	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AKN87_RS11005	COG2894	cell division
AKN87_RS11010	COG0850	regulation of cytokinetic process
AKN87_RS11015	COG1560	Kdo2-lipid A biosynthetic process
AKN87_RS11025	COG2853	Lipoprotein
AKN87_RS11040	COG0489	protein tyrosine kinase activity
AKN87_RS11045	COG1278	Cold shock
AKN87_RS11050	COG0717	Belongs to the dCTP deaminase family
AKN87_RS11100	COG0659	secondary active sulfate transmembrane transporter activity
AKN87_RS11110	COG0431	NADPH-dependent FMN reductase
AKN87_RS11115	COG0798	PFAM Bile acid sodium symporter
AKN87_RS11130	COG1595	DNA-templated transcription, initiation
AKN87_RS11160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AKN87_RS11165	COG1733	regulation of RNA biosynthetic process
AKN87_RS11200	COG0582	viral genome integration into host DNA
AKN87_RS11245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AKN87_RS11275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKN87_RS11285	COG0859	PFAM glycosyl transferase family 9
AKN87_RS11290	COG0859	PFAM glycosyl transferase family 9
AKN87_RS11295	COG0438	transferase activity, transferring glycosyl groups
AKN87_RS11320	COG2192	nodulation
AKN87_RS11325	COG0438	transferase activity, transferring glycosyl groups
AKN87_RS11355	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AKN87_RS11370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AKN87_RS11395	COG0438	transferase activity, transferring glycosyl groups
AKN87_RS11400	COG0438	transferase activity, transferring glycosyl groups
AKN87_RS11420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AKN87_RS11425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AKN87_RS11455	COG1252	NADH dehydrogenase
AKN87_RS11470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AKN87_RS11475	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKN87_RS11485	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKN87_RS11490	COG1077	Cell shape determining protein MreB Mrl
AKN87_RS11495	COG1792	Involved in formation and maintenance of cell shape
AKN87_RS11505	COG0424	maF-like protein
AKN87_RS11510	COG1530	ribonuclease E activity
AKN87_RS11520	COG0497	DNA recombination
AKN87_RS11525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AKN87_RS11530	COG0443	Heat shock 70 kDa protein
AKN87_RS11535	COG0484	heat shock protein binding
AKN87_RS11540	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AKN87_RS11560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AKN87_RS11585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AKN87_RS11590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AKN87_RS11595	COG0149	triose-phosphate isomerase activity
AKN87_RS11610	COG0779	Required for maturation of 30S ribosomal subunits
AKN87_RS11615	COG0195	Participates in both transcription termination and antitermination
AKN87_RS11620	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AKN87_RS11625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AKN87_RS11630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AKN87_RS11635	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AKN87_RS11640	COG1185	polyribonucleotide nucleotidyltransferase activity
AKN87_RS11650	COG0501	Belongs to the peptidase M48B family
AKN87_RS11655	COG3091	SprT-like family
AKN87_RS11670	COG0436	Aminotransferase
AKN87_RS11695	COG1104	cysteine desulfurase activity
AKN87_RS11705	COG0316	Belongs to the HesB IscA family
AKN87_RS11710	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AKN87_RS11750	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AKN87_RS11755	COG0124	histidyl-tRNA synthetase
AKN87_RS11770	COG1160	GTP binding
AKN87_RS11805	COG1902	pentaerythritol trinitrate reductase activity
AKN87_RS11805	COG0446	pyridine nucleotide-disulphide oxidoreductase
AKN87_RS11810	COG1530	ribonuclease E activity
AKN87_RS11830	COG0424	maF-like protein
AKN87_RS11835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AKN87_RS11845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AKN87_RS11850	COG0336	Belongs to the RNA methyltransferase TrmD family
AKN87_RS11860	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AKN87_RS11870	COG2823	Periplasmic or secreted lipoprotein
AKN87_RS11880	COG0792	nuclease activity
AKN87_RS11885	COG3107	peptidoglycan biosynthetic process
AKN87_RS11895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKN87_RS11910	COG3223	Belongs to the PsiE family
AKN87_RS11920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AKN87_RS11925	COG0312	modulator of DNA gyrase
AKN87_RS11930	COG3028	Belongs to the UPF0307 family
AKN87_RS11935	COG0312	modulator of DNA gyrase
AKN87_RS11940	COG0028	Belongs to the TPP enzyme family
AKN87_RS11955	COG1183	phosphatidylcholine synthase activity
AKN87_RS11985	COG0500	methyltransferase
AKN87_RS12005	COG0135	phosphoribosylanthranilate isomerase activity
AKN87_RS12010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AKN87_RS12015	COG0285	dihydrofolate synthase activity