locus-tag	class	description
CUC15_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CUC15_RS00010	COG0592	DNA-directed DNA polymerase activity
CUC15_RS00015	COG2501	S4 domain
CUC15_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CUC15_RS00030	COG0187	DNA topoisomerase II activity
CUC15_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CUC15_RS00040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CUC15_RS00050	COG0516	GMP reductase activity
CUC15_RS00050	COG0517	IMP dehydrogenase activity
CUC15_RS00060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CUC15_RS00070	COG2357	RelA SpoT domain protein
CUC15_RS00075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CUC15_RS00080	COG1428	Deoxynucleoside kinase
CUC15_RS00085	COG1428	Deoxynucleoside kinase
CUC15_RS00100	COG1301	dicarboxylic acid transport
CUC15_RS00105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CUC15_RS00120	COG1959	2 iron, 2 sulfur cluster binding
CUC15_RS00125	COG0693	protein deglycase activity
CUC15_RS00130	COG1388	LysM domain
CUC15_RS00130	COG3858	chitin binding
CUC15_RS00135	COG1335	isochorismatase
CUC15_RS00140	COG0590	tRNA wobble adenosine to inosine editing
CUC15_RS00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CUC15_RS00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CUC15_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CUC15_RS00180	COG1982	Orn Lys Arg decarboxylase major
CUC15_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CUC15_RS00190	COG3870	Protein conserved in bacteria
CUC15_RS00195	COG1728	Protein conserved in bacteria
CUC15_RS00200	COG0470	DNA polymerase III
CUC15_RS00205	COG1774	PSP1 C-terminal conserved region
CUC15_RS00210	COG4467	Involved in initiation control of chromosome replication
CUC15_RS00215	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CUC15_RS00220	COG2827	Endonuclease containing a URI domain
CUC15_RS00225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CUC15_RS00230	COG2002	toxin-antitoxin pair type II binding
CUC15_RS00235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC15_RS00235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC15_RS00240	COG0084	hydrolase, TatD family'
CUC15_RS00245	COG3583	domain protein
CUC15_RS00245	COG3584	3D domain protein
CUC15_RS00250	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CUC15_RS00255	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CUC15_RS00265	COG4466	Protein conserved in bacteria
CUC15_RS00275	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CUC15_RS00280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CUC15_RS00290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CUC15_RS00295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CUC15_RS00300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CUC15_RS00305	COG0193	aminoacyl-tRNA hydrolase activity
CUC15_RS00315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CUC15_RS00320	COG2002	toxin-antitoxin pair type II binding
CUC15_RS00325	COG2244	polysaccharide biosynthetic process
CUC15_RS00330	COG3956	TIGRFAM MazG family protein
CUC15_RS00335	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CUC15_RS00355	COG1098	S1 RNA binding domain
CUC15_RS00365	COG2208	phosphoserine phosphatase activity
CUC15_RS00370	COG2304	oxidoreductase activity
CUC15_RS00375	COG0515	serine threonine protein kinase
CUC15_RS00380	COG0037	tRNA processing
CUC15_RS00385	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CUC15_RS00390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CUC15_RS00395	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CUC15_RS00400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CUC15_RS00405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CUC15_RS00410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CUC15_RS00415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CUC15_RS00420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CUC15_RS00425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CUC15_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CUC15_RS00510	COG1285	pathogenesis
CUC15_RS00520	COG3880	PFAM UvrB UvrC protein
CUC15_RS00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CUC15_RS00530	COG0542	response to heat
CUC15_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
CUC15_RS00545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CUC15_RS00550	COG1045	serine acetyltransferase
CUC15_RS00555	COG0215	cysteine-tRNA ligase activity
CUC15_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUC15_RS00570	COG3688	RNA-binding protein containing a PIN domain
CUC15_RS00580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CUC15_RS00585	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CUC15_RS00590	COG0250	Participates in transcription elongation, termination and antitermination
CUC15_RS00595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CUC15_RS00600	COG0081	regulation of translation
CUC15_RS00605	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CUC15_RS00610	COG0222	ribosome binding
CUC15_RS00615	COG2813	Specifically methylates the guanine in position
CUC15_RS00620	COG0085	RNA polymerase activity
CUC15_RS00625	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CUC15_RS00635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CUC15_RS00640	COG0049	tRNA binding
CUC15_RS00645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CUC15_RS00650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CUC15_RS00655	COG0051	transcription antitermination factor activity, RNA binding
CUC15_RS00660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CUC15_RS00665	COG0088	Forms part of the polypeptide exit tunnel
CUC15_RS00670	COG0089	rRNA binding
CUC15_RS00675	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CUC15_RS00680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CUC15_RS00685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CUC15_RS00690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CUC15_RS00695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CUC15_RS00700	COG0255	Belongs to the universal ribosomal protein uL29 family
CUC15_RS00705	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CUC15_RS00710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CUC15_RS00715	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CUC15_RS00720	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CUC15_RS00725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CUC15_RS00730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CUC15_RS00735	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CUC15_RS00740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CUC15_RS00745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CUC15_RS00750	COG1841	ribosomal large subunit assembly
CUC15_RS00755	COG0200	Binds to the 23S rRNA
CUC15_RS00760	COG0201	protein transport
CUC15_RS00765	COG0563	adenylate kinase activity
CUC15_RS00770	COG2163	COG2163 Ribosomal protein L14E L6E L27E
CUC15_RS00775	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CUC15_RS00780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CUC15_RS00785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CUC15_RS00790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CUC15_RS00795	COG0202	RNA polymerase activity
CUC15_RS00800	COG0203	ribosomal protein L17
CUC15_RS00805	COG1122	ATPase activity
CUC15_RS00810	COG1122	ATPase activity
CUC15_RS00815	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CUC15_RS00820	COG0101	tRNA pseudouridine synthase activity
CUC15_RS00825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CUC15_RS00830	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CUC15_RS00840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CUC15_RS00845	COG0628	permease
CUC15_RS00860	COG1904	glucuronate isomerase
CUC15_RS00865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CUC15_RS00870	COG1940	carbohydrate kinase activity
CUC15_RS00875	COG1803	Methylglyoxal synthase
CUC15_RS00885	COG0673	inositol 2-dehydrogenase activity
CUC15_RS00915	COG1070	Carbohydrate kinase
CUC15_RS00935	COG2211	Major facilitator Superfamily
CUC15_RS00940	COG2211	Major facilitator Superfamily
CUC15_RS00945	COG2610	gluconate transmembrane transporter activity
CUC15_RS00950	COG2211	Major facilitator Superfamily
CUC15_RS00965	COG1295	ribonuclease BN
CUC15_RS00990	COG0860	N-Acetylmuramoyl-L-alanine amidase
CUC15_RS00995	COG0489	protein tyrosine kinase activity
CUC15_RS01005	COG2194	sulfuric ester hydrolase activity
CUC15_RS01010	COG0726	polysaccharide deacetylase
CUC15_RS01055	COG0628	permease
CUC15_RS01060	COG1309	transcriptional regulator
CUC15_RS01080	COG2252	PERMEase
CUC15_RS01095	COG3428	Bacterial PH domain
CUC15_RS01100	COG3402	PFAM membrane-flanked domain
CUC15_RS01115	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CUC15_RS01120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC15_RS01130	COG1131	(ABC) transporter
CUC15_RS01135	COG0840	transmembrane signaling receptor activity
CUC15_RS01215	COG1595	DNA-templated transcription, initiation
CUC15_RS01220	COG5662	AntiSigma factor
CUC15_RS01225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CUC15_RS01230	COG4856	YbbR-like protein
CUC15_RS01235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC15_RS01240	COG1388	LysM domain
CUC15_RS01240	COG1376	ErfK ybiS ycfS ynhG family protein
CUC15_RS01285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CUC15_RS01295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUC15_RS01310	COG2318	DinB family
CUC15_RS01335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC15_RS01340	COG1301	dicarboxylic acid transport
CUC15_RS01345	COG4682	membrane
CUC15_RS01350	COG1695	Transcriptional regulator
CUC15_RS01370	COG0110	maltose O-acetyltransferase activity
CUC15_RS01375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CUC15_RS01415	COG0583	DNA-binding transcription factor activity
CUC15_RS01420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CUC15_RS01425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUC15_RS01430	COG2814	Major facilitator Superfamily
CUC15_RS01440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC15_RS01445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC15_RS01450	COG1116	anion transmembrane transporter activity
CUC15_RS01465	COG0346	lactoylglutathione lyase activity
CUC15_RS01470	COG0346	lactoylglutathione lyase activity
CUC15_RS01475	COG0346	lactoylglutathione lyase activity
CUC15_RS01480	COG0400	carboxylic ester hydrolase activity
CUC15_RS01485	COG3300	MHYT domain
CUC15_RS01485	COG5001	Diguanylate cyclase
CUC15_RS01495	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CUC15_RS01500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CUC15_RS01505	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CUC15_RS01525	COG1846	Transcriptional regulator
CUC15_RS01535	COG0346	lactoylglutathione lyase activity
CUC15_RS01540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC15_RS01545	COG0431	NADPH-dependent FMN reductase
CUC15_RS01560	COG0673	inositol 2-dehydrogenase activity
CUC15_RS01570	COG0655	NAD(P)H dehydrogenase (quinone) activity
CUC15_RS01580	COG0431	NADPH-dependent FMN reductase
CUC15_RS01585	COG2211	Major facilitator Superfamily
CUC15_RS01590	COG1494	fructose-1,6-bisphosphatase
CUC15_RS01600	COG4807	Protein conserved in bacteria
CUC15_RS01610	COG0662	Cupin 2, conserved barrel domain protein
CUC15_RS01615	COG2076	Multidrug Resistance protein
CUC15_RS01625	COG1609	Transcriptional regulator
CUC15_RS01640	COG2814	Major facilitator Superfamily
CUC15_RS01645	COG0735	belongs to the Fur family
CUC15_RS01650	COG1393	Belongs to the ArsC family
CUC15_RS01655	COG1329	Transcriptional regulator
CUC15_RS01670	COG0477	Major facilitator Superfamily
CUC15_RS01675	COG0589	response to stress
CUC15_RS01695	COG1960	acyl-CoA dehydrogenase activity
CUC15_RS01715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CUC15_RS01725	COG1309	transcriptional regulator
CUC15_RS01730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUC15_RS01735	COG0583	DNA-binding transcription factor activity
CUC15_RS01745	COG0024	Methionine aminopeptidase
CUC15_RS01750	COG1801	Protein of unknown function DUF72
CUC15_RS01760	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CUC15_RS01780	COG1968	undecaprenyl-diphosphatase activity
CUC15_RS01800	COG1523	belongs to the glycosyl hydrolase 13 family
CUC15_RS01805	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CUC15_RS01810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CUC15_RS01815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CUC15_RS01820	COG0297	glycogen (starch) synthase activity
CUC15_RS01825	COG0058	SHG alpha-glucan phosphorylase activity
CUC15_RS01830	COG1114	Component of the transport system for branched-chain amino acids
CUC15_RS01835	COG2186	Transcriptional regulator
CUC15_RS01840	COG0560	Phosphoserine phosphatase
CUC15_RS01845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CUC15_RS01845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CUC15_RS01870	COG1131	(ABC) transporter
CUC15_RS01880	COG0564	pseudouridine synthase activity
CUC15_RS01945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CUC15_RS01950	COG1132	(ABC) transporter
CUC15_RS01955	COG0710	3-dehydroquinate dehydratase activity
CUC15_RS01960	COG0753	catalase activity
CUC15_RS01965	COG0535	radical SAM domain protein
CUC15_RS01975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC15_RS01985	COG0668	transmembrane transport
CUC15_RS01990	COG0204	Acyl-transferase
CUC15_RS02020	COG0400	carboxylic ester hydrolase activity
CUC15_RS02025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC15_RS02030	COG1846	Transcriptional regulator
CUC15_RS02035	COG1959	2 iron, 2 sulfur cluster binding
CUC15_RS02040	COG2910	NAD(P)H-binding
CUC15_RS02060	COG1473	amidohydrolase
CUC15_RS02065	COG0390	transport system, permease component
CUC15_RS02070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CUC15_RS02075	COG0488	(ABC) transporter
CUC15_RS02080	COG1695	Transcriptional regulator
CUC15_RS02100	COG0778	Nitroreductase
CUC15_RS02115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUC15_RS02120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUC15_RS02125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CUC15_RS02130	COG1120	ATPase activity
CUC15_RS02150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CUC15_RS02190	COG3973	AAA domain
CUC15_RS02195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUC15_RS02205	COG1695	Transcriptional regulator
CUC15_RS02230	COG1131	(ABC) transporter
CUC15_RS02250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CUC15_RS02260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CUC15_RS02270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CUC15_RS02275	COG0534	Mate efflux family protein
CUC15_RS02285	COG1733	regulation of RNA biosynthetic process
CUC15_RS02290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUC15_RS02295	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CUC15_RS02300	COG0083	homoserine kinase activity
CUC15_RS02305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CUC15_RS02310	COG0460	homoserine dehydrogenase
CUC15_RS02330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CUC15_RS02350	COG2814	Major facilitator Superfamily
CUC15_RS02360	COG1366	Belongs to the anti-sigma-factor antagonist family
CUC15_RS02365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC15_RS02380	COG0477	Major facilitator Superfamily
CUC15_RS02400	COG0789	Transcriptional regulator
CUC15_RS02405	COG1131	(ABC) transporter
CUC15_RS02410	COG0842	Transport permease protein
CUC15_RS02410	COG1511	domain protein
CUC15_RS02420	COG0456	acetyltransferase
CUC15_RS02420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CUC15_RS02425	COG0352	thiamine-phosphate diphosphorylase activity
CUC15_RS02430	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CUC15_RS02440	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CUC15_RS02465	COG4145	pantothenate transmembrane transporter activity
CUC15_RS02475	COG1413	lyase activity
CUC15_RS02480	COG0693	protein deglycase activity
CUC15_RS02490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CUC15_RS02495	COG5506	Protein of unknown function (DUF1694)
CUC15_RS02510	COG5577	PFAM Coat F domain
CUC15_RS02525	COG1472	Belongs to the glycosyl hydrolase 3 family
CUC15_RS02530	COG0708	Exodeoxyribonuclease III
CUC15_RS02535	COG1725	Transcriptional regulator
CUC15_RS02540	COG1131	(ABC) transporter
CUC15_RS02555	COG0159	tryptophan synthase activity
CUC15_RS02560	COG0133	tryptophan synthase activity
CUC15_RS02565	COG0135	phosphoribosylanthranilate isomerase activity
CUC15_RS02570	COG0134	indole-3-glycerol-phosphate synthase activity
CUC15_RS02575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CUC15_RS02580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CUC15_RS02580	COG0512	Glutamine amidotransferase of anthranilate synthase
CUC15_RS02585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CUC15_RS02590	COG2207	Transcriptional regulator
CUC15_RS02590	COG3708	Transcriptional regulator
CUC15_RS02595	COG0778	Nitroreductase
CUC15_RS02600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CUC15_RS02610	COG1418	mRNA catabolic process
CUC15_RS02615	COG1876	peptidase activity
CUC15_RS02620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CUC15_RS02625	COG2195	Cleaves the N-terminal amino acid of tripeptides
CUC15_RS02640	COG0519	Catalyzes the synthesis of GMP from XMP
CUC15_RS02645	COG0519	Catalyzes the synthesis of GMP from XMP
CUC15_RS02650	COG2329	Antibiotic biosynthesis monooxygenase
CUC15_RS02665	COG0840	transmembrane signaling receptor activity
CUC15_RS02670	COG0488	(ABC) transporter
CUC15_RS02675	COG0656	L-ascorbic acid biosynthetic process
CUC15_RS02685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CUC15_RS02695	COG1304	FMN binding
CUC15_RS02700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CUC15_RS02705	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUC15_RS02710	COG4605	iron ion homeostasis
CUC15_RS02715	COG4604	ABC transporter, ATP-binding protein
CUC15_RS02720	COG4607	ABC-type enterochelin transport system periplasmic component
CUC15_RS02735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CUC15_RS02735	COG0140	phosphoribosyl-ATP diphosphatase activity
CUC15_RS02740	COG0107	imidazoleglycerol-phosphate synthase activity
CUC15_RS02745	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CUC15_RS02750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CUC15_RS02755	COG0131	Imidazoleglycerol-phosphate dehydratase
CUC15_RS02760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CUC15_RS02765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CUC15_RS02770	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CUC15_RS02775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CUC15_RS02780	COG2832	Protein of unknown function (DUF454)
CUC15_RS02790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CUC15_RS02800	COG0673	inositol 2-dehydrogenase activity
CUC15_RS02805	COG0346	lactoylglutathione lyase activity
CUC15_RS02810	COG1876	peptidase activity
CUC15_RS02820	COG0601	transmembrane transport
CUC15_RS02825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUC15_RS02835	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CUC15_RS02840	COG2839	Protein conserved in bacteria
CUC15_RS02845	COG0351	phosphomethylpyrimidine kinase
CUC15_RS02850	COG1335	isochorismatase
CUC15_RS02855	COG0456	acetyltransferase
CUC15_RS02860	COG1335	isochorismatase
CUC15_RS02880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CUC15_RS02895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC15_RS02900	COG0765	amino acid transport
CUC15_RS02905	COG1126	abc transporter atp-binding protein
CUC15_RS02920	COG0386	Belongs to the glutathione peroxidase family
CUC15_RS02930	COG1054	Belongs to the UPF0176 family
CUC15_RS02945	COG2084	Dehydrogenase
CUC15_RS02950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CUC15_RS02960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC15_RS02965	COG0745	RESPONSE REGULATOR receiver
CUC15_RS02970	COG5002	protein histidine kinase activity
CUC15_RS02970	COG3850	Histidine kinase
CUC15_RS02975	COG1217	gtp-binding protein TYPA
CUC15_RS02985	COG1263	PTS System
CUC15_RS02985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUC15_RS02990	COG0366	Alpha amylase catalytic
CUC15_RS02995	COG2188	Transcriptional regulator
CUC15_RS03005	COG1834	amidinotransferase
CUC15_RS03015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CUC15_RS03020	COG1131	(ABC) transporter
CUC15_RS03025	COG2843	Capsule synthesis protein
CUC15_RS03040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC15_RS03050	COG0745	RESPONSE REGULATOR receiver
CUC15_RS03055	COG3850	Histidine kinase
CUC15_RS03055	COG5002	protein histidine kinase activity
CUC15_RS03075	COG2323	membrane
CUC15_RS03090	COG0737	Belongs to the 5'-nucleotidase family
CUC15_RS03095	COG1846	Transcriptional regulator
CUC15_RS03115	COG1307	EDD domain protein, DegV family
CUC15_RS03125	COG0513	Belongs to the DEAD box helicase family
CUC15_RS03130	COG3402	PFAM membrane-flanked domain
CUC15_RS03135	COG3428	Bacterial PH domain
CUC15_RS03140	COG0705	Rhomboid family
CUC15_RS03145	COG0736	holo-[acyl-carrier-protein] synthase activity
CUC15_RS03150	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CUC15_RS03160	COG2337	Toxic component of a toxin-antitoxin (TA) module
CUC15_RS03165	COG1366	Belongs to the anti-sigma-factor antagonist family
CUC15_RS03170	COG1366	Belongs to the anti-sigma-factor antagonist family
CUC15_RS03175	COG2172	sigma factor antagonist activity
CUC15_RS03180	COG2208	phosphoserine phosphatase activity
CUC15_RS03185	COG1366	Belongs to the anti-sigma-factor antagonist family
CUC15_RS03190	COG2172	sigma factor antagonist activity
CUC15_RS03195	COG1191	sigma factor activity
CUC15_RS03200	COG2208	phosphoserine phosphatase activity
CUC15_RS03205	COG2183	response to ionizing radiation
CUC15_RS03210	COG0753	catalase activity
CUC15_RS03215	COG3091	SprT-like family
CUC15_RS03300	COG0802	atpase or kinase
CUC15_RS03305	COG1214	PFAM Peptidase M22, glycoprotease
CUC15_RS03310	COG0456	acetyltransferase
CUC15_RS03315	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CUC15_RS03320	COG0772	Belongs to the SEDS family
CUC15_RS03325	COG1253	flavin adenine dinucleotide binding
CUC15_RS03330	COG0488	(ABC) transporter
CUC15_RS03335	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CUC15_RS03340	COG1266	CAAX protease self-immunity
CUC15_RS03345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CUC15_RS03350	COG0459	protein refolding
CUC15_RS03360	COG0517	IMP dehydrogenase activity
CUC15_RS03395	COG1657	PFAM Prenyltransferase squalene oxidase
CUC15_RS03450	COG5566	PFAM Mor transcription activator
CUC15_RS03480	COG5577	PFAM Coat F domain
CUC15_RS03495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CUC15_RS03505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CUC15_RS03510	COG2323	membrane
CUC15_RS03515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC15_RS03520	COG0765	amino acid transport
CUC15_RS03525	COG1126	abc transporter atp-binding protein
CUC15_RS03530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC15_RS03560	COG1113	amino acid transport
CUC15_RS03565	COG1280	lysine exporter protein (LysE YggA)
CUC15_RS03580	COG4294	response to UV
CUC15_RS03590	COG0753	catalase activity
CUC15_RS03610	COG1063	alcohol dehydrogenase
CUC15_RS03620	COG2814	Major facilitator Superfamily
CUC15_RS03625	COG2814	Major facilitator Superfamily
CUC15_RS03640	COG1136	(ABC) transporter
CUC15_RS03660	COG1414	Transcriptional regulator
CUC15_RS03695	COG0583	DNA-binding transcription factor activity
CUC15_RS03735	COG1785	Belongs to the alkaline phosphatase family
CUC15_RS03740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC15_RS03745	COG1063	alcohol dehydrogenase
CUC15_RS03750	COG2223	nitrite transmembrane transporter activity
CUC15_RS03755	COG3383	formate dehydrogenase (NAD+) activity
CUC15_RS03760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CUC15_RS03765	COG0109	protoheme IX farnesyltransferase activity
CUC15_RS03770	COG2329	Antibiotic biosynthesis monooxygenase
CUC15_RS03775	COG0667	Aldo Keto reductase
CUC15_RS03785	COG0697	spore germination
CUC15_RS03790	COG0531	amino acid
CUC15_RS03800	COG0154	amidase activity
CUC15_RS03805	COG0714	Associated with various cellular activities
CUC15_RS03810	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CUC15_RS03815	COG1305	Transglutaminase-like
CUC15_RS03820	COG0519	Catalyzes the synthesis of GMP from XMP
CUC15_RS03820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CUC15_RS03825	COG4974	Belongs to the 'phage' integrase family
CUC15_RS03860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CUC15_RS03920	COG2252	PERMEase
CUC15_RS03945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUC15_RS03950	COG1357	PFAM Pentapeptide repeats (8 copies)
CUC15_RS03965	COG2814	Major facilitator Superfamily
CUC15_RS03970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CUC15_RS03975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CUC15_RS03980	COG2258	MOSC domain
CUC15_RS03990	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CUC15_RS04005	COG1309	transcriptional regulator
CUC15_RS04010	COG0318	PFAM AMP-dependent synthetase and ligase
CUC15_RS04015	COG2030	dehydratase
CUC15_RS04020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CUC15_RS04050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CUC15_RS04060	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS04075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CUC15_RS04080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CUC15_RS04085	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CUC15_RS04090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CUC15_RS04095	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CUC15_RS04100	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CUC15_RS04105	COG0138	bifunctional purine biosynthesis protein purh
CUC15_RS04110	COG0151	Belongs to the GarS family
CUC15_RS04115	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CUC15_RS04120	COG1470	cell adhesion involved in biofilm formation
CUC15_RS04125	COG4496	protein, YerC YecD
CUC15_RS04130	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CUC15_RS04135	COG0210	DNA helicase
CUC15_RS04140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CUC15_RS04145	COG4851	CamS sex pheromone cAM373 precursor
CUC15_RS04155	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CUC15_RS04160	COG0154	amidase activity
CUC15_RS04165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CUC15_RS04170	COG1597	lipid kinase activity
CUC15_RS04175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUC15_RS04175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUC15_RS04175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUC15_RS04180	COG1105	Belongs to the carbohydrate kinase PfkB family
CUC15_RS04185	COG1349	DNA-binding transcription factor activity
CUC15_RS04195	COG0516	GMP reductase activity
CUC15_RS04195	COG0517	IMP dehydrogenase activity
CUC15_RS04200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CUC15_RS04215	COG2814	Major facilitator Superfamily
CUC15_RS04230	COG2207	Transcriptional regulator
CUC15_RS04240	COG0384	phenazine biosynthesis protein PhzF
CUC15_RS04250	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CUC15_RS04310	COG0582	viral genome integration into host DNA
CUC15_RS04365	COG1695	Transcriptional regulator
CUC15_RS04380	COG2814	Major facilitator Superfamily
CUC15_RS04435	COG0477	Major facilitator Superfamily
CUC15_RS04445	COG2508	Transcriptional regulator
CUC15_RS04450	COG0006	proline dipeptidase activity
CUC15_RS04455	COG1473	amidohydrolase
CUC15_RS04460	COG1012	belongs to the aldehyde dehydrogenase family
CUC15_RS04470	COG1027	Aspartate ammonia-lyase
CUC15_RS04475	COG0179	Fumarylacetoacetate (FAA) hydrolase
CUC15_RS04480	COG0686	Belongs to the AlaDH PNT family
CUC15_RS04495	COG1316	TRANSCRIPTIONal
CUC15_RS04630	COG1131	(ABC) transporter
CUC15_RS04660	COG2124	cytochrome p450
CUC15_RS04670	COG2271	Major facilitator Superfamily
CUC15_RS04710	COG2059	Chromate
CUC15_RS04715	COG2059	Chromate
CUC15_RS04730	COG1522	sequence-specific DNA binding
CUC15_RS04745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC15_RS04755	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CUC15_RS04775	COG2146	nitrite reductase [NAD(P)H] activity
CUC15_RS04785	COG2814	Major facilitator Superfamily
CUC15_RS04790	COG0477	Major facilitator Superfamily
CUC15_RS04795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CUC15_RS04835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUC15_RS04905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUC15_RS04910	COG2205	protein histidine kinase activity
CUC15_RS04920	COG1289	transmembrane transporter activity
CUC15_RS04945	COG2340	Cysteine-rich secretory protein family
CUC15_RS04965	COG3403	YqcI/YcgG family
CUC15_RS04990	COG1733	regulation of RNA biosynthetic process
CUC15_RS04995	COG2259	Doxx family
CUC15_RS05000	COG2514	catechol 2,3-dioxygenase activity
CUC15_RS05030	COG0436	Aminotransferase
CUC15_RS05035	COG1522	sequence-specific DNA binding
CUC15_RS05040	COG3773	Cell wall hydrolase
CUC15_RS05095	COG5002	protein histidine kinase activity
CUC15_RS05100	COG0745	RESPONSE REGULATOR receiver
CUC15_RS05105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUC15_RS05125	COG1131	(ABC) transporter
CUC15_RS05130	COG0842	Transport permease protein
CUC15_RS05140	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CUC15_RS05145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC15_RS05150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CUC15_RS05155	COG4548	von Willebrand factor, type A
CUC15_RS05160	COG0714	Associated with various cellular activities
CUC15_RS05185	COG2267	carboxylic ester hydrolase activity
CUC15_RS05190	COG0840	transmembrane signaling receptor activity
CUC15_RS05200	COG0166	Belongs to the GPI family
CUC15_RS05205	COG0564	pseudouridine synthase activity
CUC15_RS05215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC15_RS05220	COG0307	riboflavin synthase, alpha
CUC15_RS05225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUC15_RS05225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUC15_RS05230	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CUC15_RS05240	COG0488	(ABC) transporter
CUC15_RS05255	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CUC15_RS05260	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CUC15_RS05270	COG0733	neurotransmitter:sodium symporter activity
CUC15_RS05275	COG1757	Na H antiporter
CUC15_RS05295	COG1012	belongs to the aldehyde dehydrogenase family
CUC15_RS05305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CUC15_RS05325	COG1077	Cell shape determining protein MreB Mrl
CUC15_RS05335	COG2340	Cysteine-rich secretory protein family
CUC15_RS05340	COG2066	Belongs to the glutaminase family
CUC15_RS05345	COG2135	peptidase activity
CUC15_RS05350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CUC15_RS05360	COG1295	ribonuclease BN
CUC15_RS05365	COG2217	Heavy metal translocating P-type atpase
CUC15_RS05370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC15_RS05375	COG0765	amino acid transport
CUC15_RS05380	COG0477	Major facilitator Superfamily
CUC15_RS05390	COG2056	Na+-H+ antiporter family
CUC15_RS05400	COG0542	response to heat
CUC15_RS05405	COG2030	dehydratase
CUC15_RS05410	COG0658	competence protein
CUC15_RS05410	COG2333	competence protein COMEC
CUC15_RS05420	COG1725	Transcriptional regulator
CUC15_RS05425	COG1131	(ABC) transporter
CUC15_RS05435	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CUC15_RS05440	COG1131	(ABC) transporter
CUC15_RS05455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC15_RS05470	COG2137	regulation of response to DNA damage stimulus
CUC15_RS05480	COG1988	membrane-bound metal-dependent
CUC15_RS05485	COG1194	a g-specific adenine glycosylase
CUC15_RS05495	COG3557	Belongs to the UPF0374 family
CUC15_RS05500	COG1132	(ABC) transporter
CUC15_RS05505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CUC15_RS05515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CUC15_RS05520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CUC15_RS05530	COG2096	Adenosyltransferase
CUC15_RS05535	COG0735	belongs to the Fur family
CUC15_RS05705	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CUC15_RS05735	COG0514	ATP-dependent DNA helicase (RecQ)
CUC15_RS05780	COG2304	oxidoreductase activity
CUC15_RS05790	COG2031	fatty acid transporter
CUC15_RS05815	COG1309	transcriptional regulator
CUC15_RS05825	COG2207	Transcriptional regulator
CUC15_RS05825	COG1609	Transcriptional regulator
CUC15_RS05850	COG0772	Belongs to the SEDS family
CUC15_RS05915	COG1280	lysine exporter protein (LysE YggA)
CUC15_RS05975	COG1309	transcriptional regulator
CUC15_RS06015	COG0305	Participates in initiation and elongation during chromosome replication
CUC15_RS06025	COG0305	Participates in initiation and elongation during chromosome replication
CUC15_RS06045	COG1366	Belongs to the anti-sigma-factor antagonist family
CUC15_RS06055	COG0477	Major facilitator Superfamily
CUC15_RS06065	COG4572	Cation transport regulator
CUC15_RS06105	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS06110	COG1115	amino acid carrier protein
CUC15_RS06115	COG2610	gluconate transmembrane transporter activity
CUC15_RS06120	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS06140	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CUC15_RS06150	COG4176	ABC-type proline glycine betaine transport system permease component
CUC15_RS06155	COG3448	diguanylate cyclase activity
CUC15_RS06155	COG4175	Glycine betaine
CUC15_RS06165	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS06190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CUC15_RS06195	COG1012	belongs to the aldehyde dehydrogenase family
CUC15_RS06210	COG2814	Major facilitator Superfamily
CUC15_RS06215	COG2364	Membrane
CUC15_RS06230	COG0659	secondary active sulfate transmembrane transporter activity
CUC15_RS06235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUC15_RS06250	COG1227	inorganic diphosphatase activity
CUC15_RS06255	COG1278	Cold shock
CUC15_RS06265	COG1970	mechanosensitive ion channel activity
CUC15_RS06270	COG0706	membrane insertase activity
CUC15_RS06280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC15_RS06300	COG4474	Belongs to the UPF0398 family
CUC15_RS06305	COG2968	Membrane
CUC15_RS06335	COG0456	acetyltransferase
CUC15_RS06350	COG1051	belongs to the nudix hydrolase family
CUC15_RS06355	COG0456	acetyltransferase
CUC15_RS06380	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CUC15_RS06385	COG0285	dihydrofolate synthase activity
CUC15_RS06390	COG0302	gtp cyclohydrolase
CUC15_RS06395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CUC15_RS06400	COG2814	Major facilitator Superfamily
CUC15_RS06415	COG4106	trans-aconitate 2-methyltransferase activity
CUC15_RS06420	COG0745	RESPONSE REGULATOR receiver
CUC15_RS06425	COG2205	protein histidine kinase activity
CUC15_RS06430	COG1136	(ABC) transporter
CUC15_RS06435	COG0577	efflux transmembrane transporter activity
CUC15_RS06445	COG1940	carbohydrate kinase activity
CUC15_RS06450	COG2190	(PTS) system
CUC15_RS06455	COG1621	beta-fructofuranosidase activity
CUC15_RS06460	COG1263	PTS System
CUC15_RS06460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUC15_RS06470	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CUC15_RS06475	COG2224	Isocitrate lyase
CUC15_RS06505	COG4989	oxidoreductase activity
CUC15_RS06525	COG0351	phosphomethylpyrimidine kinase
CUC15_RS06535	COG0154	amidase activity
CUC15_RS06555	COG2271	Major facilitator Superfamily
CUC15_RS06560	COG4988	ABC transporter
CUC15_RS06565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CUC15_RS06575	COG1294	oxidase, subunit
CUC15_RS06580	COG1271	oxidase subunit
CUC15_RS06590	COG5583	Uncharacterized small protein (DUF2292)
CUC15_RS06595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC15_RS06615	COG2011	ABC-type metal ion transport system permease component
CUC15_RS06620	COG1464	Belongs to the NlpA lipoprotein family
CUC15_RS06625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC15_RS06640	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CUC15_RS06645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CUC15_RS06655	COG0517	IMP dehydrogenase activity
CUC15_RS06655	COG1125	glycine betaine transport
CUC15_RS06660	COG1174	glycine betaine transport
CUC15_RS06670	COG1473	amidohydrolase
CUC15_RS06680	COG4948	Mandelate Racemase Muconate Lactonizing
CUC15_RS06690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CUC15_RS06695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CUC15_RS06700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC15_RS06705	COG0765	amino acid transport
CUC15_RS06710	COG1126	abc transporter atp-binding protein
CUC15_RS06720	COG0745	RESPONSE REGULATOR receiver
CUC15_RS06725	COG0642	Histidine kinase
CUC15_RS06740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUC15_RS06750	COG2176	DNA-directed DNA polymerase activity
CUC15_RS06755	COG0318	PFAM AMP-dependent synthetase and ligase
CUC15_RS06775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CUC15_RS06780	COG2233	PERMEase
CUC15_RS06785	COG0667	Aldo Keto reductase
CUC15_RS06790	COG1902	pentaerythritol trinitrate reductase activity
CUC15_RS06805	COG0697	spore germination
CUC15_RS06830	COG4585	Histidine kinase
CUC15_RS06835	COG2197	response regulator
CUC15_RS06840	COG1131	(ABC) transporter
CUC15_RS06865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CUC15_RS06870	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CUC15_RS06875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CUC15_RS06880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CUC15_RS06885	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CUC15_RS06890	COG0823	Involved in the tonB-independent uptake of proteins
CUC15_RS06890	COG1506	peptidase
CUC15_RS06890	COG4946	Tricorn protease homolog
CUC15_RS06930	COG0567	Dehydrogenase, E1 component
CUC15_RS06935	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUC15_RS06940	COG2252	PERMEase
CUC15_RS06945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CUC15_RS06950	COG0534	Mate efflux family protein
CUC15_RS06955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CUC15_RS06975	COG0288	reversible hydration of carbon dioxide
CUC15_RS06985	COG0840	transmembrane signaling receptor activity
CUC15_RS06990	COG1132	(ABC) transporter
CUC15_RS06995	COG1132	(ABC) transporter
CUC15_RS07000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC15_RS07010	COG1191	sigma factor activity
CUC15_RS07030	COG2226	methyltransferase
CUC15_RS07035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CUC15_RS07040	COG0626	cystathionine gamma-synthase activity
CUC15_RS07055	COG0024	Methionine aminopeptidase
CUC15_RS07060	COG1757	Na H antiporter
CUC15_RS07065	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CUC15_RS07080	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CUC15_RS07095	COG0114	fumarate hydratase activity
CUC15_RS07105	COG3842	ATPase activity
CUC15_RS07110	COG2508	Transcriptional regulator
CUC15_RS07115	COG3679	Belongs to the UPF0342 family
CUC15_RS07135	COG4152	abc transporter atp-binding protein
CUC15_RS07140	COG1668	transmembrane transport
CUC15_RS07155	COG0420	3'-5' exonuclease activity
CUC15_RS07160	COG4717	serine-type aminopeptidase activity
CUC15_RS07165	COG1510	regulation of RNA biosynthetic process
CUC15_RS07170	COG3481	metal-dependent phosphohydrolase, HD sub domain
CUC15_RS07185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CUC15_RS07200	COG1510	regulation of RNA biosynthetic process
CUC15_RS07230	COG0537	adenosine 5'-monophosphoramidase activity
CUC15_RS07235	COG1131	(ABC) transporter
CUC15_RS07240	COG4473	ABC transporter
CUC15_RS07245	COG2193	ferroxidase activity
CUC15_RS07255	COG4585	Histidine kinase
CUC15_RS07260	COG2197	response regulator
CUC15_RS07265	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CUC15_RS07270	COG3118	belongs to the thioredoxin family
CUC15_RS07270	COG0492	ferredoxin-NADP+ reductase activity
CUC15_RS07310	COG0583	DNA-binding transcription factor activity
CUC15_RS07335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUC15_RS07340	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CUC15_RS07345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CUC15_RS07350	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CUC15_RS07360	COG1234	tRNA 3'-trailer cleavage
CUC15_RS07365	COG0095	Lipoate-protein ligase
CUC15_RS07380	COG0398	Pfam SNARE associated Golgi protein
CUC15_RS07390	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CUC15_RS07430	COG2311	Membrane
CUC15_RS07435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CUC15_RS07450	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS07460	COG1307	EDD domain protein, DegV family
CUC15_RS07465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUC15_RS07475	COG0561	phosphatase activity
CUC15_RS07480	COG1288	antiporter activity
CUC15_RS07485	COG2195	Cleaves the N-terminal amino acid of tripeptides
CUC15_RS07500	COG2267	carboxylic ester hydrolase activity
CUC15_RS07505	COG2368	4-hydroxyphenylacetate
CUC15_RS07515	COG1388	LysM domain
CUC15_RS07525	COG1937	Protein conserved in bacteria
CUC15_RS07530	COG2217	Heavy metal translocating P-type atpase
CUC15_RS07540	COG1073	alpha beta
CUC15_RS07545	COG2151	metal-sulfur cluster biosynthetic enzyme
CUC15_RS07565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CUC15_RS07570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUC15_RS07585	COG0180	Tryptophanyl-tRNA synthetase
CUC15_RS07595	COG3871	stress protein (general stress protein 26)
CUC15_RS07600	COG2155	Conserved Protein
CUC15_RS07620	COG0456	acetyltransferase
CUC15_RS07625	COG1393	Belongs to the ArsC family
CUC15_RS07630	COG4862	establishment of competence for transformation
CUC15_RS07640	COG1164	Oligoendopeptidase f
CUC15_RS07645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CUC15_RS07650	COG2346	COG2346, Truncated hemoglobins
CUC15_RS07655	COG4116	CYTH
CUC15_RS07660	COG2357	RelA SpoT domain protein
CUC15_RS07665	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CUC15_RS07670	COG0564	pseudouridine synthase activity
CUC15_RS07675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CUC15_RS07680	COG2239	Acts as a magnesium transporter
CUC15_RS07710	COG2323	membrane
CUC15_RS07715	COG2153	protein acetylation
CUC15_RS07720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CUC15_RS07725	COG2382	esterase
CUC15_RS07730	COG1132	(ABC) transporter
CUC15_RS07735	COG1132	(ABC) transporter
CUC15_RS07750	COG5577	PFAM Coat F domain
CUC15_RS07760	COG1063	alcohol dehydrogenase
CUC15_RS07765	COG5577	PFAM Coat F domain
CUC15_RS07795	COG0071	Belongs to the small heat shock protein (HSP20) family
CUC15_RS07835	COG1278	Cold shock
CUC15_RS07860	COG3546	catalase activity
CUC15_RS07870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC15_RS07875	COG0424	maF-like protein
CUC15_RS07885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CUC15_RS07905	COG2323	membrane
CUC15_RS07915	COG2268	Band 7 protein
CUC15_RS07920	COG1585	Membrane protein implicated in regulation of membrane protease activity
CUC15_RS07930	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CUC15_RS07940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CUC15_RS07945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CUC15_RS07950	COG0671	phosphoesterase, PA-phosphatase related
CUC15_RS07955	COG0438	transferase activity, transferring glycosyl groups
CUC15_RS07970	COG2081	HI0933 family
CUC15_RS07975	COG2244	polysaccharide biosynthetic process
CUC15_RS07980	COG1187	pseudouridine synthase activity
CUC15_RS07995	COG1597	lipid kinase activity
CUC15_RS08000	COG0510	thiamine kinase activity
CUC15_RS08010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CUC15_RS08015	COG4260	virion core protein, lumpy skin disease virus
CUC15_RS08020	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CUC15_RS08025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CUC15_RS08030	COG1842	Phage shock protein A
CUC15_RS08040	COG2404	hydrolase activity, acting on ester bonds
CUC15_RS08045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CUC15_RS08050	COG0726	polysaccharide deacetylase
CUC15_RS08055	COG1408	metallophosphoesterase
CUC15_RS08070	COG3361	conserved protein (COG2071)
CUC15_RS08075	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CUC15_RS08100	COG3583	domain protein
CUC15_RS08100	COG3584	3D domain protein
CUC15_RS08110	COG0488	(ABC) transporter
CUC15_RS08120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC15_RS08130	COG2226	methyltransferase
CUC15_RS08140	COG5504	Zn-dependent protease
CUC15_RS08170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUC15_RS08170	COG2190	(PTS) system
CUC15_RS08170	COG1263	PTS System
CUC15_RS08180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CUC15_RS08185	COG1472	Belongs to the glycosyl hydrolase 3 family
CUC15_RS08190	COG0387	Pfam Sodium calcium exchanger
CUC15_RS08195	COG3584	3D domain protein
CUC15_RS08195	COG1388	LysM domain
CUC15_RS08210	COG3842	ATPase activity
CUC15_RS08215	COG1175	transmembrane transport
CUC15_RS08220	COG0395	ABC-type sugar transport system, permease component
CUC15_RS08230	COG0584	glycerophosphoryl diester phosphodiesterase
CUC15_RS08235	COG0584	glycerophosphoryl diester phosphodiesterase
CUC15_RS08245	COG2309	aminopeptidase activity
CUC15_RS08255	COG2814	Major facilitator Superfamily
CUC15_RS08260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC15_RS08265	COG1802	Transcriptional regulator
CUC15_RS08270	COG1063	alcohol dehydrogenase
CUC15_RS08285	COG2027	D-alanyl-D-alanine carboxypeptidase
CUC15_RS08290	COG0626	cystathionine gamma-synthase activity
CUC15_RS08295	COG0626	cystathionine gamma-synthase activity
CUC15_RS08300	COG2814	Major facilitator Superfamily
CUC15_RS08315	COG2304	oxidoreductase activity
CUC15_RS08320	COG1252	NADH dehydrogenase
CUC15_RS08325	COG2720	vancomycin resistance protein
CUC15_RS08330	COG2353	YceI-like domain
CUC15_RS08335	COG3069	C4-dicarboxylate transmembrane transporter activity
CUC15_RS08340	COG0604	alcohol dehydrogenase
CUC15_RS08345	COG2323	membrane
CUC15_RS08360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CUC15_RS08380	COG0778	Nitroreductase
CUC15_RS08390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CUC15_RS08400	COG0681	Belongs to the peptidase S26 family
CUC15_RS08425	COG1999	signal sequence binding
CUC15_RS08430	COG1408	metallophosphoesterase
CUC15_RS08440	COG0640	Transcriptional regulator
CUC15_RS08445	COG0517	IMP dehydrogenase activity
CUC15_RS08455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC15_RS08460	COG1132	(ABC) transporter
CUC15_RS08465	COG1132	(ABC) transporter
CUC15_RS08470	COG0569	domain protein
CUC15_RS08475	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CUC15_RS08480	COG5503	Protein of unknown function (DUF1447)
CUC15_RS08485	COG0242	peptide deformylase activity
CUC15_RS08530	COG4493	Belongs to the UPF0637 family
CUC15_RS08540	COG0483	inositol monophosphate 1-phosphatase activity
CUC15_RS08565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CUC15_RS08570	COG4838	Belongs to the UPF0358 family
CUC15_RS08575	COG0772	Belongs to the SEDS family
CUC15_RS08580	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CUC15_RS08585	COG1612	heme a metabolic process
CUC15_RS08590	COG0109	protoheme IX farnesyltransferase activity
CUC15_RS08595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CUC15_RS08595	COG2010	Cytochrome c
CUC15_RS08600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CUC15_RS08605	COG1845	cytochrome c oxidase, subunit III
CUC15_RS08615	COG3336	cytochrome c oxidase
CUC15_RS08630	COG2340	Cysteine-rich secretory protein family
CUC15_RS08645	COG3679	Belongs to the UPF0342 family
CUC15_RS08650	COG4471	UPF0298 protein
CUC15_RS08655	COG0742	ribosomal rna small subunit methyltransferase
CUC15_RS08660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CUC15_RS08665	COG3314	Sporulation integral membrane protein YlbJ
CUC15_RS08670	COG3480	Lon protease (S16) C-terminal proteolytic domain
CUC15_RS08675	COG1323	Belongs to the UPF0348 family
CUC15_RS08680	COG1399	metal-binding, possibly nucleic acid-binding protein
CUC15_RS08685	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CUC15_RS08700	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CUC15_RS08705	COG2001	Belongs to the MraZ family
CUC15_RS08710	COG0275	rRNA processing
CUC15_RS08715	COG4839	cell division protein FtsL
CUC15_RS08720	COG0768	penicillin binding
CUC15_RS08725	COG0768	penicillin binding
CUC15_RS08730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CUC15_RS08735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CUC15_RS08740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CUC15_RS08745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CUC15_RS08750	COG0772	Belongs to the SEDS family
CUC15_RS08755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CUC15_RS08760	COG0849	cell division
CUC15_RS08765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CUC15_RS08775	COG1191	sigma factor activity
CUC15_RS08780	COG1191	sigma factor activity
CUC15_RS08785	COG1873	PFAM PRC-barrel domain
CUC15_RS08790	COG1496	oxidoreductase activity
CUC15_RS08795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CUC15_RS08800	COG1799	cell septum assembly
CUC15_RS08805	COG0762	integral membrane protein
CUC15_RS08810	COG2302	S4 RNA-binding domain
CUC15_RS08815	COG3599	regulation of cell shape
CUC15_RS08820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CUC15_RS08825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CUC15_RS08830	COG0564	pseudouridine synthase activity
CUC15_RS08835	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CUC15_RS08840	COG0540	Belongs to the ATCase OTCase family
CUC15_RS08845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CUC15_RS08850	COG0505	Belongs to the CarA family
CUC15_RS08860	COG0543	2 iron, 2 sulfur cluster binding
CUC15_RS08865	COG0167	dihydroorotate dehydrogenase activity
CUC15_RS08870	COG0284	orotidine-5'-phosphate decarboxylase activity
CUC15_RS08875	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CUC15_RS08880	COG2226	methyltransferase
CUC15_RS08885	COG0583	DNA-binding transcription factor activity
CUC15_RS08890	COG1764	response to oxidative stress
CUC15_RS08895	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CUC15_RS08900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CUC15_RS08905	COG1561	YicC-like family, N-terminal region
CUC15_RS08910	COG2052	Domain of unknown function (DUF370)
CUC15_RS08915	COG0194	GDP metabolic process
CUC15_RS08920	COG1758	RNA polymerase activity
CUC15_RS08925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CUC15_RS08930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CUC15_RS08935	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CUC15_RS08940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CUC15_RS08940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CUC15_RS08945	COG0631	protein serine/threonine phosphatase activity
CUC15_RS08950	COG0515	serine threonine protein kinase
CUC15_RS08950	COG2815	serine threonine protein kinase
CUC15_RS08955	COG1162	GTPase activity
CUC15_RS08960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CUC15_RS08965	COG1564	THIamine pyrophosphokinase
CUC15_RS08975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CUC15_RS08980	COG1302	Protein conserved in bacteria
CUC15_RS08985	COG1461	Dihydroxyacetone kinase
CUC15_RS08990	COG1760	l-serine dehydratase
CUC15_RS08995	COG1760	l-serine dehydratase
CUC15_RS09000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CUC15_RS09005	COG1349	DNA-binding transcription factor activity
CUC15_RS09010	COG0416	fatty acid biosynthetic process
CUC15_RS09015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CUC15_RS09020	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS09025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUC15_RS09030	COG0571	ribonuclease III activity
CUC15_RS09035	COG4840	Belongs to the UPF0435 family
CUC15_RS09040	COG1196	nuclear chromosome segregation
CUC15_RS09045	COG0552	protein localization to endoplasmic reticulum
CUC15_RS09050	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CUC15_RS09055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CUC15_RS09060	COG0228	four-way junction DNA binding
CUC15_RS09065	COG1837	Belongs to the UPF0109 family
CUC15_RS09075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CUC15_RS09080	COG0336	Belongs to the RNA methyltransferase TrmD family
CUC15_RS09085	COG0335	large ribosomal subunit rRNA binding
CUC15_RS09090	COG0681	Belongs to the peptidase S26 family
CUC15_RS09100	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CUC15_RS09110	COG2257	FlhB HrpN YscU SpaS Family
CUC15_RS09115	COG0045	succinate-CoA ligase (ADP-forming) activity
CUC15_RS09120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CUC15_RS09125	COG0758	DNA mediated transformation
CUC15_RS09130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CUC15_RS09135	COG4974	Belongs to the 'phage' integrase family
CUC15_RS09140	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CUC15_RS09145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CUC15_RS09150	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CUC15_RS09155	COG1815	bacterial-type flagellum-dependent cell motility
CUC15_RS09160	COG1558	bacterial-type flagellum-dependent cell motility
CUC15_RS09165	COG1677	Flagellar hook-basal body complex protein FliE
CUC15_RS09170	COG1766	The M ring may be actively involved in energy transduction
CUC15_RS09175	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CUC15_RS09180	COG1317	bacterial-type flagellum organization
CUC15_RS09185	COG1157	protein secretion by the type III secretion system
CUC15_RS09205	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CUC15_RS09215	COG4786	Flagellar basal body rod
CUC15_RS09220	COG1582	Flagellar protein (FlbD)
CUC15_RS09225	COG1580	Controls the rotational direction of flagella during chemotaxis
CUC15_RS09230	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CUC15_RS09235	COG1776	CheC inhibitor of MCP methylation
CUC15_RS09235	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CUC15_RS09240	COG2201	protein-glutamate methylesterase activity
CUC15_RS09245	COG3190	flagellar
CUC15_RS09250	COG1338	Plays a role in the flagellum-specific transport system
CUC15_RS09255	COG1987	bacterial-type flagellum assembly
CUC15_RS09260	COG1684	flagellar biosynthetic protein fliR
CUC15_RS09265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CUC15_RS09270	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CUC15_RS09275	COG1419	protein localization to endoplasmic reticulum
CUC15_RS09280	COG0455	bacterial-type flagellum organization
CUC15_RS09285	COG2201	protein-glutamate methylesterase activity
CUC15_RS09290	COG0835	chemotaxis
CUC15_RS09295	COG1776	CheC inhibitor of MCP methylation
CUC15_RS09300	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CUC15_RS09305	COG1191	sigma factor activity
CUC15_RS09315	COG0052	Belongs to the universal ribosomal protein uS2 family
CUC15_RS09320	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CUC15_RS09325	COG0528	UMP kinase activity
CUC15_RS09330	COG0233	cytoplasmic translational termination
CUC15_RS09335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CUC15_RS09340	COG4589	Belongs to the CDS family
CUC15_RS09345	COG0750	zinc metalloprotease
CUC15_RS09350	COG2176	DNA-directed DNA polymerase activity
CUC15_RS09355	COG0779	Required for maturation of 30S ribosomal subunits
CUC15_RS09360	COG0195	Participates in both transcription termination and antitermination
CUC15_RS09365	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CUC15_RS09370	COG1358	cellular component organization or biogenesis
CUC15_RS09375	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CUC15_RS09380	COG1550	Protein conserved in bacteria
CUC15_RS09385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CUC15_RS09390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CUC15_RS09395	COG0196	riboflavin kinase activity
CUC15_RS09400	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CUC15_RS09405	COG1185	polyribonucleotide nucleotidyltransferase activity
CUC15_RS09410	COG0726	polysaccharide deacetylase
CUC15_RS09415	COG0612	Peptidase, M16
CUC15_RS09420	COG1873	PFAM PRC-barrel domain
CUC15_RS09425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CUC15_RS09430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CUC15_RS09435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CUC15_RS09440	COG0527	aspartate kinase activity
CUC15_RS09445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC15_RS09450	COG0740	serine-type endopeptidase activity
CUC15_RS09460	COG1674	ftsk spoiiie
CUC15_RS09465	COG1744	ABC transporter substrate-binding protein PnrA-like
CUC15_RS09470	COG3845	ABC transporter
CUC15_RS09475	COG4603	Belongs to the binding-protein-dependent transport system permease family
CUC15_RS09480	COG1079	Belongs to the binding-protein-dependent transport system permease family
CUC15_RS09485	COG0612	Peptidase, M16
CUC15_RS09490	COG0612	Peptidase, M16
CUC15_RS09495	COG0300	oxidoreductase activity
CUC15_RS09505	COG1426	Protein conserved in bacteria
CUC15_RS09510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CUC15_RS09515	COG1546	Belongs to the CinA family
CUC15_RS09515	COG1058	Belongs to the CinA family
CUC15_RS09520	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CUC15_RS09525	COG1418	mRNA catabolic process
CUC15_RS09530	COG1692	metallophosphoesterase
CUC15_RS09535	COG2359	stage V sporulation protein S
CUC15_RS09540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CUC15_RS09545	COG4550	Control of competence regulator ComK, YlbF/YmcA
CUC15_RS09555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CUC15_RS09560	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CUC15_RS09565	COG0783	Belongs to the Dps family
CUC15_RS09570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CUC15_RS09575	COG1923	regulation of RNA biosynthetic process
CUC15_RS09580	COG0464	growth
CUC15_RS09585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CUC15_RS09590	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CUC15_RS09595	COG0789	Transcriptional regulator
CUC15_RS09600	COG0174	glutamine synthetase
CUC15_RS09605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CUC15_RS09610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CUC15_RS09615	COG4224	UPF0291 protein
CUC15_RS09625	COG3763	UPF0154 protein
CUC15_RS09645	COG1525	nuclease
CUC15_RS09755	COG3763	UPF0154 protein
CUC15_RS09765	COG0785	Cytochrome C biogenesis protein
CUC15_RS09770	COG2201	protein-glutamate methylesterase activity
CUC15_RS09775	COG4846	Membrane protein involved in cytochrome C biogenesis
CUC15_RS09785	COG4191	Histidine kinase
CUC15_RS09790	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CUC15_RS09795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC15_RS09810	COG0824	Thioesterase
CUC15_RS09820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CUC15_RS09825	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CUC15_RS09830	COG1832	CoA-binding protein
CUC15_RS09835	COG0187	DNA topoisomerase II activity
CUC15_RS09840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CUC15_RS09845	COG1960	acyl-CoA dehydrogenase activity
CUC15_RS09850	COG4770	biotin carboxylase activity
CUC15_RS09855	COG0511	ligase activity, forming carbon-carbon bonds
CUC15_RS09860	COG1024	Enoyl-CoA hydratase
CUC15_RS09865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CUC15_RS09870	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CUC15_RS09875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CUC15_RS09880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CUC15_RS09890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CUC15_RS09895	COG3011	Protein conserved in bacteria
CUC15_RS09910	COG0772	Belongs to the SEDS family
CUC15_RS09955	COG1366	Belongs to the anti-sigma-factor antagonist family
CUC15_RS09965	COG2333	competence protein COMEC
CUC15_RS09965	COG0658	competence protein
CUC15_RS09970	COG1902	pentaerythritol trinitrate reductase activity
CUC15_RS09995	COG0384	phenazine biosynthesis protein PhzF
CUC15_RS10015	COG1733	regulation of RNA biosynthetic process
CUC15_RS10025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC15_RS10030	COG0431	NADPH-dependent FMN reductase
CUC15_RS10035	COG1733	regulation of RNA biosynthetic process
CUC15_RS10040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CUC15_RS10045	COG2085	NADP oxidoreductase coenzyme F420-dependent
CUC15_RS10065	COG1742	UPF0060 membrane protein
CUC15_RS10085	COG1309	transcriptional regulator
CUC15_RS10200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CUC15_RS10205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CUC15_RS10215	COG0745	RESPONSE REGULATOR receiver
CUC15_RS10220	COG2205	protein histidine kinase activity
CUC15_RS10225	COG1131	(ABC) transporter
CUC15_RS10235	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CUC15_RS10315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CUC15_RS10350	COG1309	transcriptional regulator
CUC15_RS10375	COG0604	alcohol dehydrogenase
CUC15_RS10405	COG0438	transferase activity, transferring glycosyl groups
CUC15_RS10430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CUC15_RS10430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CUC15_RS10445	COG4479	Belongs to the UPF0346 family
CUC15_RS10450	COG0805	protein transport
CUC15_RS10455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CUC15_RS10460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CUC15_RS10465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CUC15_RS10470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CUC15_RS10475	COG1418	mRNA catabolic process
CUC15_RS10485	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CUC15_RS10490	COG0116	Belongs to the methyltransferase superfamily
CUC15_RS10500	COG3599	regulation of cell shape
CUC15_RS10505	COG0295	cytidine deaminase activity
CUC15_RS10520	COG3331	DNA recombination
CUC15_RS10525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUC15_RS10525	COG4499	WXG100 protein secretion system (Wss), protein YukC
CUC15_RS10530	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CUC15_RS10535	COG3935	DnaD domain protein
CUC15_RS10540	COG0017	Asparaginyl-tRNA synthetase
CUC15_RS10550	COG1199	ATP-dependent helicase activity
CUC15_RS10550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUC15_RS10560	COG0617	tRNA 3'-terminal CCA addition
CUC15_RS10565	COG0438	transferase activity, transferring glycosyl groups
CUC15_RS10570	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CUC15_RS10575	COG1694	Mazg nucleotide pyrophosphohydrolase
CUC15_RS10580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUC15_RS10585	COG2738	Putative neutral zinc metallopeptidase
CUC15_RS10595	COG4347	Protein of unknown function (DUF1405)
CUC15_RS10605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CUC15_RS10610	COG0723	plastoquinol--plastocyanin reductase activity
CUC15_RS10620	COG5582	Belongs to the UPF0302 family
CUC15_RS10625	COG0457	Tetratricopeptide repeat
CUC15_RS10630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CUC15_RS10635	COG0287	Prephenate dehydrogenase
CUC15_RS10640	COG4401	Chorismate mutase type I
CUC15_RS10645	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CUC15_RS10650	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CUC15_RS10655	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CUC15_RS10660	COG0105	UTP biosynthetic process
CUC15_RS10665	COG0142	geranyltranstransferase activity
CUC15_RS10675	COG0142	geranyltranstransferase activity
CUC15_RS10685	COG0776	regulation of translation
CUC15_RS10690	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CUC15_RS10710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CUC15_RS10715	COG1160	GTP binding
CUC15_RS10730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CUC15_RS10735	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CUC15_RS10740	COG2959	enzyme of heme biosynthesis
CUC15_RS10745	COG3773	Cell wall hydrolase
CUC15_RS10745	COG3409	Peptidoglycan-binding domain 1 protein
CUC15_RS10750	COG2339	peptidase activity
CUC15_RS10755	COG0252	asparaginase activity
CUC15_RS10760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CUC15_RS10765	COG1181	Belongs to the D-alanine--D-alanine ligase family
CUC15_RS10770	COG4862	establishment of competence for transformation
CUC15_RS10780	COG0514	ATP-dependent DNA helicase (RecQ)
CUC15_RS10785	COG4955	Helix-turn-helix domain
CUC15_RS10805	COG5002	protein histidine kinase activity
CUC15_RS10810	COG0745	RESPONSE REGULATOR receiver
CUC15_RS10815	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CUC15_RS10820	COG1333	cytochrome c biogenesis protein
CUC15_RS10825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC15_RS10830	COG1187	pseudouridine synthase activity
CUC15_RS10835	COG0700	Nucleoside recognition
CUC15_RS10840	COG2715	membrane protein required for spore maturation
CUC15_RS10845	COG1686	Belongs to the peptidase S11 family
CUC15_RS10850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CUC15_RS10855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CUC15_RS10860	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CUC15_RS10880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CUC15_RS10885	COG0019	diaminopimelate decarboxylase activity
CUC15_RS10890	COG0697	spore germination
CUC15_RS10905	COG1191	sigma factor activity
CUC15_RS10910	COG2172	sigma factor antagonist activity
CUC15_RS10920	COG1686	Belongs to the peptidase S11 family
CUC15_RS10925	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CUC15_RS10935	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CUC15_RS10940	COG4974	Belongs to the 'phage' integrase family
CUC15_RS10950	COG0735	belongs to the Fur family
CUC15_RS10955	COG1300	Membrane
CUC15_RS10960	COG1379	DNA repair
CUC15_RS10975	COG1234	tRNA 3'-trailer cleavage
CUC15_RS10980	COG1012	belongs to the aldehyde dehydrogenase family
CUC15_RS10985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CUC15_RS10990	COG2195	Cleaves the N-terminal amino acid of tripeptides
CUC15_RS10995	COG4129	membrane
CUC15_RS11005	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUC15_RS11010	COG0022	dehydrogenase e1 component
CUC15_RS11015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CUC15_RS11020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUC15_RS11035	COG0527	aspartate kinase activity
CUC15_RS11040	COG0745	RESPONSE REGULATOR receiver
CUC15_RS11045	COG0750	zinc metalloprotease
CUC15_RS11050	COG0497	DNA recombination
CUC15_RS11055	COG1438	arginine binding
CUC15_RS11060	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CUC15_RS11065	COG0142	geranyltranstransferase activity
CUC15_RS11070	COG1722	exodeoxyribonuclease VII activity
CUC15_RS11075	COG1570	exodeoxyribonuclease VII activity
CUC15_RS11080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CUC15_RS11085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CUC15_RS11090	COG1302	Protein conserved in bacteria
CUC15_RS11095	COG0439	Biotin carboxylase
CUC15_RS11100	COG0511	ligase activity, forming carbon-carbon bonds
CUC15_RS11140	COG3854	ATPases associated with a variety of cellular activities
CUC15_RS11145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CUC15_RS11150	COG0006	proline dipeptidase activity
CUC15_RS11165	COG1752	Esterase of the alpha-beta hydrolase superfamily
CUC15_RS11170	COG1321	iron dependent repressor
CUC15_RS11175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUC15_RS11180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CUC15_RS11185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CUC15_RS11190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CUC15_RS11195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CUC15_RS11200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CUC15_RS11215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CUC15_RS11225	COG4537	Required for transformation and DNA binding
CUC15_RS11260	COG1368	sulfuric ester hydrolase activity
CUC15_RS11265	COG1940	carbohydrate kinase activity
CUC15_RS11275	COG0705	Rhomboid family
CUC15_RS11275	COG0457	Tetratricopeptide repeat
CUC15_RS11280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CUC15_RS11300	COG0768	penicillin binding
CUC15_RS11305	COG0477	Major facilitator Superfamily
CUC15_RS11345	COG1030	water channel activity
CUC15_RS11355	COG4709	membrane
CUC15_RS11365	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CUC15_RS11370	COG0513	Belongs to the DEAD box helicase family
CUC15_RS11375	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CUC15_RS11380	COG2384	SAM-dependent methyltransferase
CUC15_RS11385	COG2010	Cytochrome c
CUC15_RS11395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CUC15_RS11400	COG0358	DNA primase activity
CUC15_RS11405	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CUC15_RS11410	COG0517	IMP dehydrogenase activity
CUC15_RS11415	COG0751	glycine-tRNA ligase activity
CUC15_RS11420	COG0752	glycyl-tRNA synthetase alpha subunit
CUC15_RS11425	COG1381	Involved in DNA repair and RecF pathway recombination
CUC15_RS11435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CUC15_RS11440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CUC15_RS11445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CUC15_RS11450	COG1480	7TM receptor with intracellular HD hydrolase
CUC15_RS11455	COG1702	phosphate starvation-inducible protein PhoH
CUC15_RS11475	COG4864	UPF0365 protein
CUC15_RS11480	COG1030	water channel activity
CUC15_RS11485	COG1610	YqeY-like protein
CUC15_RS11490	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CUC15_RS11495	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CUC15_RS11500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CUC15_RS11505	COG2264	protein methyltransferase activity
CUC15_RS11510	COG0484	heat shock protein binding
CUC15_RS11515	COG0443	Heat shock 70 kDa protein
CUC15_RS11520	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CUC15_RS11525	COG1420	regulation of RNA biosynthetic process
CUC15_RS11530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CUC15_RS11535	COG0481	GTPase activity
CUC15_RS11545	COG0860	N-Acetylmuramoyl-L-alanine amidase
CUC15_RS11550	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CUC15_RS11555	COG0268	Binds directly to 16S ribosomal RNA
CUC15_RS11560	COG1466	dna polymerase III delta subunit
CUC15_RS11570	COG0658	competence protein
CUC15_RS11570	COG2333	competence protein COMEC
CUC15_RS11575	COG0658	competence protein
CUC15_RS11575	COG2333	competence protein COMEC
CUC15_RS11580	COG2131	deaminase
CUC15_RS11585	COG1596	polysaccharide export
CUC15_RS11585	COG1555	photosystem II stabilization
CUC15_RS11590	COG2226	methyltransferase
CUC15_RS11595	COG0799	negative regulation of ribosome biogenesis
CUC15_RS11600	COG1713	HD superfamily hydrolase involved in NAD metabolism
CUC15_RS11605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CUC15_RS11610	COG1534	Rna-binding protein
CUC15_RS11615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CUC15_RS11620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CUC15_RS11625	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CUC15_RS11640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CUC15_RS11665	COG0631	protein serine/threonine phosphatase activity
CUC15_RS11730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CUC15_RS11735	COG0572	uridine kinase
CUC15_RS11740	COG4122	O-methyltransferase activity
CUC15_RS11745	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CUC15_RS11750	COG3906	Belongs to the UPF0473 family
CUC15_RS11755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CUC15_RS11760	COG4472	Bacterial protein of unknown function (DUF965)
CUC15_RS11765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CUC15_RS11770	COG0628	permease
CUC15_RS11780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CUC15_RS11790	COG0482	sulfurtransferase activity
CUC15_RS11795	COG1104	cysteine desulfurase activity
CUC15_RS11800	COG1959	2 iron, 2 sulfur cluster binding
CUC15_RS11805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CUC15_RS11820	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CUC15_RS11825	COG0124	histidyl-tRNA synthetase
CUC15_RS11830	COG0860	N-Acetylmuramoyl-L-alanine amidase
CUC15_RS11830	COG3103	Sh3 type 3 domain protein
CUC15_RS11830	COG4991	sh3 domain protein
CUC15_RS11835	COG1490	D-aminoacyl-tRNA deacylase activity
CUC15_RS11840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CUC15_RS11845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CUC15_RS11850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CUC15_RS11850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CUC15_RS11860	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CUC15_RS11860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CUC15_RS11870	COG2244	polysaccharide biosynthetic process
CUC15_RS11880	COG1862	Preprotein translocase
CUC15_RS11885	COG0343	queuine tRNA-ribosyltransferase activity
CUC15_RS11890	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CUC15_RS11900	COG2255	four-way junction helicase activity
CUC15_RS11905	COG0632	four-way junction helicase activity
CUC15_RS11910	COG0217	transcriptional regulatory protein
CUC15_RS11925	COG0077	Prephenate dehydratase
CUC15_RS11930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CUC15_RS11945	COG2868	ribosomal protein
CUC15_RS11950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CUC15_RS11955	COG1994	Peptidase M50
CUC15_RS11965	COG2894	cell division
CUC15_RS11970	COG0850	regulation of cytokinetic process
CUC15_RS11975	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CUC15_RS11985	COG1077	Cell shape determining protein MreB Mrl
CUC15_RS11995	COG2003	Belongs to the UPF0758 family
CUC15_RS12005	COG0525	valine-tRNA ligase activity
CUC15_RS12020	COG1388	LysM domain
CUC15_RS12020	COG1388	LysM domain
CUC15_RS12025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CUC15_RS12040	COG0181	hydroxymethylbilane synthase activity
CUC15_RS12045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CUC15_RS12050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CUC15_RS12060	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CUC15_RS12070	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CUC15_RS12075	COG0544	peptidyl-prolyl cis-trans isomerase activity
CUC15_RS12095	COG0622	Phosphoesterase
CUC15_RS12100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CUC15_RS12105	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CUC15_RS12110	COG5401	PFAM Sporulation and spore germination
CUC15_RS12115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CUC15_RS12120	COG1846	Transcriptional regulator
CUC15_RS12130	COG2197	response regulator
CUC15_RS12135	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CUC15_RS12140	COG1053	succinate dehydrogenase
CUC15_RS12145	COG2009	succinate dehydrogenase
CUC15_RS12150	COG1719	4-vinyl reductase, 4VR
CUC15_RS12155	COG0322	excinuclease ABC activity
CUC15_RS12160	COG3118	belongs to the thioredoxin family
CUC15_RS12165	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CUC15_RS12170	COG2086	electron transfer activity
CUC15_RS12175	COG1024	Enoyl-CoA hydratase
CUC15_RS12180	COG1309	transcriptional regulator
CUC15_RS12185	COG0318	PFAM AMP-dependent synthetase and ligase
CUC15_RS12190	COG3766	membrane
CUC15_RS12195	COG1193	negative regulation of DNA recombination
CUC15_RS12200	COG1796	DNA polymerase
CUC15_RS12200	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CUC15_RS12210	COG1286	toxin biosynthetic process
CUC15_RS12215	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CUC15_RS12220	COG0072	phenylalanine-tRNA ligase activity
CUC15_RS12220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC15_RS12225	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CUC15_RS12230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUC15_RS12270	COG1131	(ABC) transporter
CUC15_RS12275	COG0741	lytic transglycosylase activity
CUC15_RS12280	COG1363	Peptidase, m42
CUC15_RS12285	COG0756	dUTP diphosphatase activity
CUC15_RS12295	COG0398	Pfam SNARE associated Golgi protein
CUC15_RS12305	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CUC15_RS12315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CUC15_RS12320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CUC15_RS12335	COG1484	DNA-dependent DNA replication
CUC15_RS12340	COG3611	Membrane attachment protein
CUC15_RS12345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CUC15_RS12355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CUC15_RS12360	COG0237	dephospho-CoA kinase activity
CUC15_RS12365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CUC15_RS12370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CUC15_RS12370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CUC15_RS12375	COG5002	protein histidine kinase activity
CUC15_RS12380	COG0745	RESPONSE REGULATOR receiver
CUC15_RS12385	COG0039	L-malate dehydrogenase activity
CUC15_RS12390	COG0538	isocitrate dehydrogenase activity
CUC15_RS12395	COG0372	Belongs to the citrate synthase family
CUC15_RS12400	COG0628	permease
CUC15_RS12405	COG3030	protein affecting phage T7 exclusion by the F plasmid
CUC15_RS12415	COG0205	6-phosphofructokinase activity
CUC15_RS12420	COG0825	malonyl-CoA metabolic process
CUC15_RS12425	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CUC15_RS12430	COG2186	Transcriptional regulator
CUC15_RS12435	COG0281	malic enzyme
CUC15_RS12440	COG0587	DNA-directed DNA polymerase activity
CUC15_RS12455	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CUC15_RS12480	COG4109	DRTGG domain
CUC15_RS12490	COG0305	Participates in initiation and elongation during chromosome replication
CUC15_RS12530	COG1459	type II secretion system
CUC15_RS12540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CUC15_RS12550	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CUC15_RS12555	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CUC15_RS12560	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CUC15_RS12575	COG1842	Phage shock protein A
CUC15_RS12590	COG0006	proline dipeptidase activity
CUC15_RS12595	COG0589	response to stress
CUC15_RS12600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CUC15_RS12605	COG0827	DNA restriction-modification system
CUC15_RS12610	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CUC15_RS12615	COG3874	Sporulation protein YtfJ
CUC15_RS12625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CUC15_RS12635	COG0301	tRNA thio-modification
CUC15_RS12640	COG1104	cysteine desulfurase activity
CUC15_RS12645	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CUC15_RS12650	COG1309	transcriptional regulator
CUC15_RS12655	COG1956	GAF domain-containing protein
CUC15_RS12660	COG2203	Gaf domain
CUC15_RS12660	COG2199	diguanylate cyclase activity
CUC15_RS12665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CUC15_RS12670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CUC15_RS12680	COG0454	-acetyltransferase
CUC15_RS12685	COG0517	IMP dehydrogenase activity
CUC15_RS12690	COG0123	including yeast histone deacetylase and acetoin utilization protein
CUC15_RS12695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CUC15_RS12700	COG1794	racemase activity, acting on amino acids and derivatives
CUC15_RS12725	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CUC15_RS12725	COG1605	Chorismate mutase
CUC15_RS12745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CUC15_RS12755	COG1674	ftsk spoiiie
CUC15_RS12760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC15_RS12765	COG4848	Belongs to the UPF0354 family
CUC15_RS12770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC15_RS12790	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CUC15_RS12795	COG1363	Peptidase, m42
CUC15_RS12805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC15_RS12810	COG0346	lactoylglutathione lyase activity
CUC15_RS12830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUC15_RS12845	COG0385	Bile acid
CUC15_RS12850	COG4841	protein insertion into membrane
CUC15_RS12855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CUC15_RS12865	COG0515	serine threonine protein kinase
CUC15_RS12880	COG0829	nickel cation binding
CUC15_RS12885	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CUC15_RS12890	COG0830	nickel cation binding
CUC15_RS12895	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CUC15_RS12900	COG0804	urea catabolic process
CUC15_RS12905	COG0832	Belongs to the urease beta subunit family
CUC15_RS12910	COG0831	urea catabolic process
CUC15_RS12915	COG4413	Urea transporter
CUC15_RS12925	COG0084	hydrolase, TatD family'
CUC15_RS12935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC15_RS12940	COG0011	TIGRFAM Protein of
CUC15_RS12945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC15_RS12950	COG1126	abc transporter atp-binding protein
CUC15_RS12955	COG0765	amino acid transport
CUC15_RS12970	COG1012	belongs to the aldehyde dehydrogenase family
CUC15_RS12975	COG3290	protein histidine kinase activity
CUC15_RS12975	COG3829	transcription factor binding
CUC15_RS12980	COG0419	ATPase involved in DNA repair
CUC15_RS12995	COG3425	synthase
CUC15_RS13000	COG0328	RNA-DNA hybrid ribonuclease activity
CUC15_RS13005	COG2200	EAL domain
CUC15_RS13015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC15_RS13030	COG1309	transcriptional regulator
CUC15_RS13035	COG2814	Major facilitator Superfamily
CUC15_RS13040	COG0300	oxidoreductase activity
CUC15_RS13045	COG0028	Belongs to the TPP enzyme family
CUC15_RS13050	COG0436	Aminotransferase
CUC15_RS13055	COG1098	S1 RNA binding domain
CUC15_RS13075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CUC15_RS13080	COG5001	Diguanylate cyclase
CUC15_RS13080	COG3300	MHYT domain
CUC15_RS13090	COG4187	Peptidase family M20/M25/M40
CUC15_RS13095	COG1263	PTS System
CUC15_RS13095	COG2190	(PTS) system
CUC15_RS13095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUC15_RS13100	COG3711	transcriptional antiterminator
CUC15_RS13105	COG0673	inositol 2-dehydrogenase activity
CUC15_RS13110	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUC15_RS13120	COG1879	ABC-type sugar transport system periplasmic component
CUC15_RS13135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CUC15_RS13140	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CUC15_RS13145	COG0640	Transcriptional regulator
CUC15_RS13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUC15_RS13150	COG0723	plastoquinol--plastocyanin reductase activity
CUC15_RS13185	COG0495	leucyl-tRNA aminoacylation
CUC15_RS13190	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CUC15_RS13215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CUC15_RS13220	COG2318	DinB family
CUC15_RS13225	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CUC15_RS13230	COG0667	Aldo Keto reductase
CUC15_RS13235	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CUC15_RS13240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC15_RS13245	COG1116	anion transmembrane transporter activity
CUC15_RS13250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC15_RS13255	COG0494	nUDIX hydrolase
CUC15_RS13270	COG0668	transmembrane transport
CUC15_RS13275	COG0318	PFAM AMP-dependent synthetase and ligase
CUC15_RS13280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CUC15_RS13285	COG0596	Alpha beta hydrolase
CUC15_RS13290	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CUC15_RS13295	COG1169	isochorismate synthase
CUC15_RS13300	COG1575	Belongs to the MenA family. Type 1 subfamily
CUC15_RS13305	COG2050	protein possibly involved in aromatic compounds catabolism
CUC15_RS13310	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CUC15_RS13315	COG4412	M6 family metalloprotease domain protein
CUC15_RS13315	COG1404	Belongs to the peptidase S8 family
CUC15_RS13320	COG1063	alcohol dehydrogenase
CUC15_RS13335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUC15_RS13340	COG1098	S1 RNA binding domain
CUC15_RS13345	COG0166	Belongs to the GPI family
CUC15_RS13350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CUC15_RS13355	COG2032	superoxide dismutase activity
CUC15_RS13370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUC15_RS13375	COG0813	purine-nucleoside phosphorylase activity
CUC15_RS13385	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CUC15_RS13390	COG3584	3D domain protein
CUC15_RS13400	COG1252	NADH dehydrogenase
CUC15_RS13405	COG0492	ferredoxin-NADP+ reductase activity
CUC15_RS13410	COG0316	Belongs to the HesB IscA family
CUC15_RS13415	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CUC15_RS13420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CUC15_RS13425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CUC15_RS13430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CUC15_RS13435	COG0647	UMP catabolic process
CUC15_RS13440	COG2445	Protein of unknown function DUF86
CUC15_RS13445	COG0154	amidase activity
CUC15_RS13450	COG4470	Protein conserved in bacteria
CUC15_RS13455	COG0739	heme binding
CUC15_RS13460	COG1757	Na H antiporter
CUC15_RS13470	COG3377	Domain of unknown function (DUF1805)
CUC15_RS13475	COG0737	Belongs to the 5'-nucleotidase family
CUC15_RS13480	COG0730	response to heat
CUC15_RS13485	COG0431	NADPH-dependent FMN reductase
CUC15_RS13490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CUC15_RS13500	COG0730	response to heat
CUC15_RS13505	COG0583	DNA-binding transcription factor activity
CUC15_RS13510	COG0719	Fe-S assembly protein
CUC15_RS13515	COG0822	iron-sulfur transferase activity
CUC15_RS13520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CUC15_RS13525	COG0719	Fe-S assembly protein
CUC15_RS13530	COG0396	ATPase activity
CUC15_RS13535	COG1464	Belongs to the NlpA lipoprotein family
CUC15_RS13540	COG2011	ABC-type metal ion transport system permease component
CUC15_RS13545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CUC15_RS13550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC15_RS13555	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CUC15_RS13560	COG0509	glycine decarboxylation via glycine cleavage system
CUC15_RS13565	COG1393	Belongs to the ArsC family
CUC15_RS13570	COG1960	acyl-CoA dehydrogenase activity
CUC15_RS13575	COG0183	Belongs to the thiolase family
CUC15_RS13580	COG1024	Enoyl-CoA hydratase
CUC15_RS13580	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUC15_RS13590	COG1121	(ABC) transporter
CUC15_RS13595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CUC15_RS13600	COG0735	belongs to the Fur family
CUC15_RS13625	COG0456	acetyltransferase
CUC15_RS13630	COG1253	flavin adenine dinucleotide binding
CUC15_RS13635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUC15_RS13640	COG3883	PFAM NLP P60 protein
CUC15_RS13640	COG0791	NLP P60 protein
CUC15_RS13645	COG2197	response regulator
CUC15_RS13655	COG4758	membrane
CUC15_RS13670	COG0586	Pfam SNARE associated Golgi protein
CUC15_RS13675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC15_RS13680	COG1363	Peptidase, m42
CUC15_RS13690	COG1272	protein, Hemolysin III
CUC15_RS13695	COG2267	carboxylic ester hydrolase activity
CUC15_RS13705	COG1714	RDD family
CUC15_RS13710	COG0616	signal peptide processing
CUC15_RS13720	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CUC15_RS13725	COG1691	(AIR) carboxylase
CUC15_RS13730	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CUC15_RS13735	COG1606	tRNA processing
CUC15_RS13740	COG1404	Belongs to the peptidase S8 family
CUC15_RS13760	COG1268	BioY protein
CUC15_RS13765	COG0318	PFAM AMP-dependent synthetase and ligase
CUC15_RS13770	COG0183	Belongs to the thiolase family
CUC15_RS13775	COG2030	dehydratase
CUC15_RS13785	COG3341	Caulimovirus viroplasmin
CUC15_RS13785	COG0328	RNA-DNA hybrid ribonuclease activity
CUC15_RS13805	COG0789	Transcriptional regulator
CUC15_RS13810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC15_RS13855	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CUC15_RS13860	COG0428	transporter
CUC15_RS13865	COG0557	exoribonuclease II activity
CUC15_RS13870	COG1647	Serine aminopeptidase, S33
CUC15_RS13875	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CUC15_RS13895	COG0148	phosphopyruvate hydratase activity
CUC15_RS13900	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CUC15_RS13905	COG0149	triose-phosphate isomerase activity
CUC15_RS13910	COG0126	phosphoglycerate kinase activity
CUC15_RS13915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CUC15_RS13920	COG2390	Transcriptional regulator
CUC15_RS13930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUC15_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS13985	COG0596	Alpha beta hydrolase
CUC15_RS14045	COG2267	carboxylic ester hydrolase activity
CUC15_RS14050	COG0179	Fumarylacetoacetate (FAA) hydrolase
CUC15_RS14060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CUC15_RS14075	COG0740	serine-type endopeptidase activity
CUC15_RS14080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUC15_RS14085	COG1481	regulation of sporulation
CUC15_RS14090	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CUC15_RS14095	COG1660	Displays ATPase and GTPase activities
CUC15_RS14100	COG0492	ferredoxin-NADP+ reductase activity
CUC15_RS14105	COG0457	Tetratricopeptide repeat
CUC15_RS14110	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CUC15_RS14115	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CUC15_RS14120	COG1461	Dihydroxyacetone kinase
CUC15_RS14125	COG2376	Dihydroxyacetone kinase
CUC15_RS14130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CUC15_RS14135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CUC15_RS14140	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CUC15_RS14145	COG0110	maltose O-acetyltransferase activity
CUC15_RS14150	COG0546	phosphoglycolate phosphatase activity
CUC15_RS14155	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CUC15_RS14160	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CUC15_RS14165	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CUC15_RS14175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CUC15_RS14185	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CUC15_RS14190	COG0556	nucleotide-excision repair
CUC15_RS14195	COG1619	proteins homologs of microcin C7 resistance protein MccF
CUC15_RS14205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC15_RS14210	COG3409	Peptidoglycan-binding domain 1 protein
CUC15_RS14210	COG0793	Belongs to the peptidase S41A family
CUC15_RS14220	COG0739	heme binding
CUC15_RS14225	COG2177	Part of the ABC transporter FtsEX involved in
CUC15_RS14230	COG2884	Cell division ATP-binding protein ftsE
CUC15_RS14245	COG0653	protein targeting
CUC15_RS14250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CUC15_RS14260	COG1516	flagellar protein fliS
CUC15_RS14265	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CUC15_RS14270	COG1334	flagellar protein FlaG
CUC15_RS14275	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CUC15_RS14280	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CUC15_RS14290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CUC15_RS14295	COG1256	bacterial-type flagellum assembly
CUC15_RS14295	COG4786	Flagellar basal body rod
CUC15_RS14320	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CUC15_RS14330	COG1307	EDD domain protein, DegV family
CUC15_RS14335	COG2197	response regulator
CUC15_RS14345	COG1739	Uncharacterized protein family UPF0029
CUC15_RS14370	COG1316	TRANSCRIPTIONal
CUC15_RS14375	COG0768	penicillin binding
CUC15_RS14380	COG1122	ATPase activity
CUC15_RS14415	COG0583	DNA-binding transcription factor activity
CUC15_RS14420	COG2855	membrane
CUC15_RS14425	COG0561	phosphatase activity
CUC15_RS14430	COG2814	Major facilitator Superfamily
CUC15_RS14440	COG0643	Histidine kinase
CUC15_RS14440	COG2198	Histidine kinase
CUC15_RS14450	COG0840	transmembrane signaling receptor activity
CUC15_RS14455	COG1360	Flagellar Motor Protein
CUC15_RS14460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CUC15_RS14475	COG0840	transmembrane signaling receptor activity
CUC15_RS14485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CUC15_RS14490	COG1472	Belongs to the glycosyl hydrolase 3 family
CUC15_RS14495	COG3876	Protein conserved in bacteria
CUC15_RS14500	COG0395	ABC-type sugar transport system, permease component
CUC15_RS14505	COG1175	transmembrane transport
CUC15_RS14515	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CUC15_RS14520	COG1737	Transcriptional regulator
CUC15_RS14525	COG2971	BadF BadG BcrA BcrD
CUC15_RS14530	COG0716	FMN binding
CUC15_RS14535	COG0366	Alpha amylase catalytic
CUC15_RS14540	COG1082	Xylose isomerase domain protein TIM barrel
CUC15_RS14545	COG0673	inositol 2-dehydrogenase activity
CUC15_RS14550	COG0673	inositol 2-dehydrogenase activity
CUC15_RS14560	COG1609	Transcriptional regulator
CUC15_RS14570	COG3833	ABC-type maltose transport systems, permease component
CUC15_RS14575	COG1175	transmembrane transport
CUC15_RS14580	COG2182	Extracellular solute-binding protein
CUC15_RS14590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CUC15_RS14595	COG2814	Major facilitator Superfamily
CUC15_RS14600	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CUC15_RS14615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC15_RS14620	COG0785	Cytochrome C biogenesis protein
CUC15_RS14720	COG0730	response to heat
CUC15_RS14740	COG0529	Catalyzes the synthesis of activated sulfate
CUC15_RS14745	COG2046	Belongs to the sulfate adenylyltransferase family
CUC15_RS14755	COG2815	serine threonine protein kinase
CUC15_RS14755	COG0515	serine threonine protein kinase
CUC15_RS14760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CUC15_RS14765	COG1971	Probably functions as a manganese efflux pump
CUC15_RS14770	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS14785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC15_RS14790	COG1131	(ABC) transporter
CUC15_RS14800	COG2996	Protein conserved in bacteria
CUC15_RS14820	COG4895	conserved protein (DUF2196)
CUC15_RS14835	COG0561	phosphatase activity
CUC15_RS14840	COG2059	Chromate
CUC15_RS14845	COG2059	Chromate
CUC15_RS14855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CUC15_RS14865	COG0747	negative chemotaxis
CUC15_RS14875	COG0601	transmembrane transport
CUC15_RS14880	COG4608	Belongs to the ABC transporter superfamily
CUC15_RS14890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CUC15_RS14895	COG0066	3-isopropylmalate dehydratase activity
CUC15_RS14900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CUC15_RS14905	COG0473	3-isopropylmalate dehydrogenase activity
CUC15_RS14910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CUC15_RS14915	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CUC15_RS14920	COG0440	acetolactate synthase activity
CUC15_RS14925	COG0028	Belongs to the TPP enzyme family
CUC15_RS14930	COG0129	dihydroxy-acid dehydratase activity
CUC15_RS14940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CUC15_RS14945	COG1011	Hydrolase
CUC15_RS14950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CUC15_RS14970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUC15_RS14980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC15_RS14990	COG2873	o-acetylhomoserine
CUC15_RS15000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC15_RS15005	COG0431	NADPH-dependent FMN reductase
CUC15_RS15050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CUC15_RS15060	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CUC15_RS15065	COG1349	DNA-binding transcription factor activity
CUC15_RS15070	COG0561	phosphatase activity
CUC15_RS15075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CUC15_RS15090	COG2719	SpoVR family
CUC15_RS15100	COG2718	Belongs to the UPF0229 family
CUC15_RS15105	COG2766	serine protein kinase
CUC15_RS15115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CUC15_RS15130	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CUC15_RS15175	COG3739	integral membrane protein
CUC15_RS15180	COG3655	Transcriptional regulator
CUC15_RS15190	COG1619	proteins homologs of microcin C7 resistance protein MccF
CUC15_RS15195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUC15_RS15200	COG1733	regulation of RNA biosynthetic process
CUC15_RS15205	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CUC15_RS15210	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CUC15_RS15255	COG2610	gluconate transmembrane transporter activity
CUC15_RS15260	COG0183	Belongs to the thiolase family
CUC15_RS15265	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS15270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CUC15_RS15275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CUC15_RS15290	COG1024	Enoyl-CoA hydratase
CUC15_RS15300	COG1024	Enoyl-CoA hydratase
CUC15_RS15310	COG0183	Belongs to the thiolase family
CUC15_RS15330	COG1960	acyl-CoA dehydrogenase activity
CUC15_RS15365	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS15380	COG0318	PFAM AMP-dependent synthetase and ligase
CUC15_RS15385	COG1024	Enoyl-CoA hydratase
CUC15_RS15390	COG0318	PFAM AMP-dependent synthetase and ligase
CUC15_RS15395	COG0318	PFAM AMP-dependent synthetase and ligase
CUC15_RS15415	COG1309	transcriptional regulator
CUC15_RS15420	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS15430	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CUC15_RS15435	COG2079	MmgE PrpD family protein
CUC15_RS15445	COG0583	DNA-binding transcription factor activity
CUC15_RS15455	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CUC15_RS15460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CUC15_RS15465	COG3835	regulator
CUC15_RS15470	COG1929	Belongs to the glycerate kinase type-1 family
CUC15_RS15480	COG3875	lactate racemase activity
CUC15_RS15495	COG4336	lyase activity
CUC15_RS15500	COG1984	allophanate hydrolase subunit 2
CUC15_RS15505	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CUC15_RS15510	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CUC15_RS15515	COG1914	H( )-stimulated, divalent metal cation uptake system
CUC15_RS15525	COG1473	amidohydrolase
CUC15_RS15530	COG3853	Toxic anion resistance protein (TelA)
CUC15_RS15535	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CUC15_RS15550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC15_RS15580	COG0658	competence protein
CUC15_RS15580	COG2333	competence protein COMEC
CUC15_RS15590	COG4990	cell redox homeostasis
CUC15_RS15595	COG0367	asparagine synthase
CUC15_RS15600	COG1404	Belongs to the peptidase S8 family
CUC15_RS15600	COG4412	M6 family metalloprotease domain protein
CUC15_RS15605	COG2233	PERMEase
CUC15_RS15610	COG0561	phosphatase activity
CUC15_RS15615	COG2706	6-phosphogluconolactonase activity
CUC15_RS15625	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUC15_RS15630	COG3162	membrane
CUC15_RS15635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CUC15_RS15640	COG3279	Response regulator of the LytR AlgR family
CUC15_RS15645	COG3275	phosphorelay sensor kinase activity
CUC15_RS15650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUC15_RS15660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUC15_RS15675	COG2723	6-phospho-beta-galactosidase activity
CUC15_RS15680	COG1486	melibiose metabolic process
CUC15_RS15685	COG1447	Phosphotransferase system cellobiose-specific component IIA
CUC15_RS15690	COG3711	transcriptional antiterminator
CUC15_RS15690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUC15_RS15705	COG2261	transglycosylase associated protein
CUC15_RS15710	COG1119	ATPase activity
CUC15_RS15720	COG1830	Aldolase
CUC15_RS15745	COG2390	Transcriptional regulator
CUC15_RS15765	COG0277	FAD linked oxidase domain protein
CUC15_RS15785	COG1653	transport
CUC15_RS15790	COG0395	ABC-type sugar transport system, permease component
CUC15_RS15795	COG1175	transmembrane transport
CUC15_RS15800	COG3842	ATPase activity
CUC15_RS15805	COG1349	DNA-binding transcription factor activity
CUC15_RS15820	COG0604	alcohol dehydrogenase
CUC15_RS15820	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS15820	COG3321	synthase
CUC15_RS15830	COG0546	phosphoglycolate phosphatase activity
CUC15_RS15835	COG0653	protein targeting
CUC15_RS15840	COG0673	inositol 2-dehydrogenase activity
CUC15_RS15845	COG0673	inositol 2-dehydrogenase activity
CUC15_RS15850	COG3833	ABC-type maltose transport systems, permease component
CUC15_RS15855	COG4209	transmembrane transport
CUC15_RS15875	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CUC15_RS15880	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CUC15_RS15885	COG0546	phosphoglycolate phosphatase activity
CUC15_RS15895	COG4129	membrane
CUC15_RS15900	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUC15_RS15905	COG2814	Major facilitator Superfamily
CUC15_RS15915	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC15_RS15930	COG0840	transmembrane signaling receptor activity
CUC15_RS15940	COG1012	belongs to the aldehyde dehydrogenase family
CUC15_RS15945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CUC15_RS15950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC15_RS15955	COG0303	'Molybdopterin
CUC15_RS15960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CUC15_RS15965	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CUC15_RS15975	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CUC15_RS15980	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CUC15_RS15990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CUC15_RS16015	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CUC15_RS16020	COG0439	Biotin carboxylase
CUC15_RS16030	COG1984	allophanate hydrolase subunit 2
CUC15_RS16040	COG0584	glycerophosphoryl diester phosphodiesterase
CUC15_RS16090	COG2011	ABC-type metal ion transport system permease component
CUC15_RS16100	COG0371	Dehydrogenase
CUC15_RS16105	COG0436	Aminotransferase
CUC15_RS16110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CUC15_RS16125	COG0598	Magnesium transport protein CorA
CUC15_RS16130	COG0315	cyclic pyranopterin monophosphate synthase activity
CUC15_RS16150	COG4149	molybdate abc transporter
CUC15_RS16155	COG0725	ABC transporter, periplasmic molybdate-binding protein
CUC15_RS16160	COG0521	Mo-molybdopterin cofactor biosynthetic process
CUC15_RS16175	COG1763	Mo-molybdopterin cofactor biosynthetic process
CUC15_RS16185	COG0303	'Molybdopterin
CUC15_RS16190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CUC15_RS16195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CUC15_RS16205	COG1268	BioY protein
CUC15_RS16210	COG1278	Cold shock
CUC15_RS16220	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CUC15_RS16225	COG1272	protein, Hemolysin III
CUC15_RS16230	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CUC15_RS16235	COG1793	dna ligase
CUC15_RS16235	COG3285	dna ligase
CUC15_RS16240	COG0589	response to stress
CUC15_RS16260	COG0693	protein deglycase activity
CUC15_RS16275	COG1349	DNA-binding transcription factor activity
CUC15_RS16280	COG3842	ATPase activity
CUC15_RS16285	COG1176	ABC-type spermidine putrescine transport system, permease component I
CUC15_RS16305	COG0640	Transcriptional regulator
CUC15_RS16310	COG0346	lactoylglutathione lyase activity
CUC15_RS16315	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CUC15_RS16350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUC15_RS16355	COG1177	transmembrane transport
CUC15_RS16360	COG1176	ABC-type spermidine putrescine transport system, permease component I
CUC15_RS16365	COG3842	ATPase activity
CUC15_RS16370	COG1840	ABC-type Fe3 transport system, periplasmic component
CUC15_RS16390	COG1396	sequence-specific DNA binding
CUC15_RS16400	COG2207	Transcriptional regulator
CUC15_RS16400	COG4753	response regulator
CUC15_RS16405	COG2972	Histidine kinase
CUC15_RS16410	COG1653	transport
CUC15_RS16415	COG0395	ABC-type sugar transport system, permease component
CUC15_RS16425	COG5578	integral membrane protein
CUC15_RS16450	COG1388	LysM domain
CUC15_RS16450	COG3858	chitin binding
CUC15_RS16455	COG0145	ligase activity
CUC15_RS16465	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CUC15_RS16480	COG2160	L-arabinose isomerase activity
CUC15_RS16495	COG1609	Transcriptional regulator
CUC15_RS16515	COG1473	amidohydrolase
CUC15_RS16520	COG1063	alcohol dehydrogenase
CUC15_RS16540	COG1129	ABC transporter
CUC15_RS16560	COG2247	cell wall binding repeat
CUC15_RS16560	COG2385	sporulation resulting in formation of a cellular spore
CUC15_RS16565	COG2089	acid synthase
CUC15_RS16605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CUC15_RS16610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CUC15_RS16640	COG1940	carbohydrate kinase activity
CUC15_RS16645	COG0395	ABC-type sugar transport system, permease component
CUC15_RS16650	COG1175	transmembrane transport
CUC15_RS16670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CUC15_RS16675	COG0110	maltose O-acetyltransferase activity
CUC15_RS16680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CUC15_RS16685	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CUC15_RS16730	COG2197	response regulator
CUC15_RS16735	COG4464	protein tyrosine phosphatase activity
CUC15_RS16740	COG0489	protein tyrosine kinase activity
CUC15_RS16745	COG3944	biosynthesis protein
CUC15_RS16750	COG0791	NLP P60 protein
CUC15_RS16750	COG1388	LysM domain
CUC15_RS16780	COG1653	transport
CUC15_RS16785	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS16795	COG1879	ABC-type sugar transport system periplasmic component
CUC15_RS16800	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUC15_RS16805	COG1129	ABC transporter
CUC15_RS16810	COG1082	Xylose isomerase domain protein TIM barrel
CUC15_RS16815	COG2207	Transcriptional regulator
CUC15_RS16820	COG0673	inositol 2-dehydrogenase activity
CUC15_RS16830	COG0191	fructose-bisphosphate aldolase activity
CUC15_RS16835	COG0673	inositol 2-dehydrogenase activity
CUC15_RS16840	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUC15_RS16850	COG0673	inositol 2-dehydrogenase activity
CUC15_RS16855	COG3962	Belongs to the TPP enzyme family
CUC15_RS16860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUC15_RS16865	COG3718	enzyme involved in inositol metabolism
CUC15_RS16870	COG1012	belongs to the aldehyde dehydrogenase family
CUC15_RS16875	COG2814	Major facilitator Superfamily
CUC15_RS16880	COG1942	4-Oxalocrotonate Tautomerase
CUC15_RS16885	COG1349	DNA-binding transcription factor activity
CUC15_RS16890	COG1349	DNA-binding transcription factor activity
CUC15_RS16895	COG1482	cell wall glycoprotein biosynthetic process
CUC15_RS16900	COG1940	carbohydrate kinase activity
CUC15_RS16905	COG0395	ABC-type sugar transport system, permease component
CUC15_RS16910	COG1175	transmembrane transport
CUC15_RS16920	COG4753	response regulator
CUC15_RS16920	COG2207	Transcriptional regulator
CUC15_RS16925	COG2972	Histidine kinase
CUC15_RS16935	COG0561	phosphatase activity
CUC15_RS16940	COG3250	beta-galactosidase activity
CUC15_RS16945	COG0395	ABC-type sugar transport system, permease component
CUC15_RS16950	COG1175	transmembrane transport
CUC15_RS16965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUC15_RS16970	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CUC15_RS16975	COG2017	converts alpha-aldose to the beta-anomer
CUC15_RS16980	COG1940	carbohydrate kinase activity
CUC15_RS16990	COG1486	melibiose metabolic process
CUC15_RS16995	COG1447	Phosphotransferase system cellobiose-specific component IIA
CUC15_RS17005	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUC15_RS17020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CUC15_RS17050	COG1175	transmembrane transport
CUC15_RS17055	COG2182	Extracellular solute-binding protein
CUC15_RS17060	COG0561	phosphatase activity
CUC15_RS17065	COG0246	Mannitol dehydrogenase
CUC15_RS17075	COG3711	transcriptional antiterminator
CUC15_RS17080	COG2213	PTS system mannitol-specific
CUC15_RS17085	COG0363	glucosamine-6-phosphate deaminase activity
CUC15_RS17090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CUC15_RS17095	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CUC15_RS17100	COG2190	(PTS) system
CUC15_RS17100	COG1263	PTS System
CUC15_RS17100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUC15_RS17110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUC15_RS17110	COG2190	(PTS) system
CUC15_RS17110	COG1263	PTS System
CUC15_RS17140	COG3458	cephalosporin-C deacetylase activity
CUC15_RS17150	COG0673	inositol 2-dehydrogenase activity
CUC15_RS17175	COG4948	Mandelate Racemase Muconate Lactonizing
CUC15_RS17180	COG0673	inositol 2-dehydrogenase activity
CUC15_RS17190	COG0395	ABC-type sugar transport system, permease component
CUC15_RS17205	COG5578	integral membrane protein
CUC15_RS17220	COG1486	melibiose metabolic process
CUC15_RS17225	COG1653	transport
CUC15_RS17265	COG2356	endonuclease I
CUC15_RS17270	COG0328	RNA-DNA hybrid ribonuclease activity
CUC15_RS17280	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CUC15_RS17285	COG1316	TRANSCRIPTIONal
CUC15_RS17305	COG4412	M6 family metalloprotease domain protein
CUC15_RS17305	COG1404	Belongs to the peptidase S8 family
CUC15_RS17310	COG1404	Belongs to the peptidase S8 family
CUC15_RS17310	COG4412	M6 family metalloprotease domain protein
CUC15_RS17315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CUC15_RS17325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUC15_RS17340	COG1134	teichoic acid transport
CUC15_RS17345	COG1682	transport, permease protein
CUC15_RS17350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CUC15_RS17355	COG0438	transferase activity, transferring glycosyl groups
CUC15_RS17375	COG0737	Belongs to the 5'-nucleotidase family
CUC15_RS17380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CUC15_RS17400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CUC15_RS17430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CUC15_RS17440	COG4786	Flagellar basal body rod
CUC15_RS17445	COG4786	Flagellar basal body rod
CUC15_RS17450	COG1077	Cell shape determining protein MreB Mrl
CUC15_RS17460	COG1609	Transcriptional regulator
CUC15_RS17470	COG0739	heme binding
CUC15_RS17475	COG2385	sporulation resulting in formation of a cellular spore
CUC15_RS17480	COG4608	Belongs to the ABC transporter superfamily
CUC15_RS17485	COG1619	proteins homologs of microcin C7 resistance protein MccF
CUC15_RS17490	COG4166	transmembrane transport
CUC15_RS17495	COG0444	Belongs to the ABC transporter superfamily
CUC15_RS17500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUC15_RS17505	COG0601	transmembrane transport
CUC15_RS17515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CUC15_RS17525	COG4836	Membrane
CUC15_RS17530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CUC15_RS17535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CUC15_RS17540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CUC15_RS17545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CUC15_RS17550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CUC15_RS17555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CUC15_RS17560	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CUC15_RS17565	COG0356	it plays a direct role in the translocation of protons across the membrane
CUC15_RS17575	COG1404	Belongs to the peptidase S8 family
CUC15_RS17580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CUC15_RS17585	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CUC15_RS17590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CUC15_RS17595	COG4475	Protein of unknown function (DUF436)
CUC15_RS17600	COG0698	ribose 5-phosphate isomerase
CUC15_RS17605	COG0840	transmembrane signaling receptor activity
CUC15_RS17610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CUC15_RS17615	COG1971	Probably functions as a manganese efflux pump
CUC15_RS17620	COG0009	L-threonylcarbamoyladenylate synthase
CUC15_RS17640	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CUC15_RS17645	COG1435	thymidine kinase activity
CUC15_RS17650	COG0254	rRNA binding
CUC15_RS17655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CUC15_RS17660	COG1494	fructose-1,6-bisphosphatase
CUC15_RS17665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CUC15_RS17670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CUC15_RS17675	COG0191	fructose-bisphosphate aldolase activity
CUC15_RS17680	COG2204	response regulator
CUC15_RS17685	COG0504	CTP synthase activity
CUC15_RS17690	COG3343	RNA polymerase activity
CUC15_RS17695	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CUC15_RS17695	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CUC15_RS17695	COG1703	isobutyryl-CoA mutase activity
CUC15_RS17705	COG1960	acyl-CoA dehydrogenase activity
CUC15_RS17710	COG1960	acyl-CoA dehydrogenase activity
CUC15_RS17715	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUC15_RS17720	COG0183	Belongs to the thiolase family
CUC15_RS17725	COG0247	lactate metabolic process
CUC15_RS17725	COG2181	nitrate reductase activity
CUC15_RS17730	COG0018	arginyl-trna synthetase
CUC15_RS17740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUC15_RS17750	COG3465	dGTPase activity
CUC15_RS17755	COG1078	dGTPase activity
CUC15_RS17760	COG0095	Lipoate-protein ligase
CUC15_RS17765	COG0280	phosphate acetyltransferase
CUC15_RS17770	COG3253	May function as heme-dependent peroxidase
CUC15_RS17785	COG2363	Small membrane protein
CUC15_RS17800	COG2312	Erythromycin esterase
CUC15_RS17805	COG3655	Transcriptional regulator
CUC15_RS17820	COG0671	phosphoesterase, PA-phosphatase related
CUC15_RS17830	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CUC15_RS17835	COG3314	Sporulation integral membrane protein YlbJ
CUC15_RS17840	COG3594	Acyltransferase
CUC15_RS17850	COG1764	response to oxidative stress
CUC15_RS17860	COG3189	MarR family transcriptional regulator
CUC15_RS17865	COG0861	Integral membrane protein TerC family
CUC15_RS17870	COG0861	Integral membrane protein TerC family
CUC15_RS17875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC15_RS17880	COG0628	permease
CUC15_RS17910	COG0514	ATP-dependent DNA helicase (RecQ)
CUC15_RS17930	COG1733	regulation of RNA biosynthetic process
CUC15_RS17935	COG1607	acyl-coa hydrolase
CUC15_RS17940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CUC15_RS17945	COG2962	Rard protein
CUC15_RS17970	COG0488	(ABC) transporter
CUC15_RS17975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUC15_RS17980	COG0156	8-amino-7-oxononanoate synthase activity
CUC15_RS17985	COG3584	3D domain protein
CUC15_RS17985	COG1388	LysM domain
CUC15_RS17990	COG4608	Belongs to the ABC transporter superfamily
CUC15_RS17995	COG0444	Belongs to the ABC transporter superfamily
CUC15_RS18000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUC15_RS18005	COG0601	transmembrane transport
CUC15_RS18010	COG4166	transmembrane transport
CUC15_RS18020	COG2814	Major facilitator Superfamily
CUC15_RS18025	COG1979	alcohol dehydrogenase
CUC15_RS18030	COG0251	oxidation-reduction process
CUC15_RS18035	COG0791	NLP P60 protein
CUC15_RS18035	COG0741	lytic transglycosylase activity
CUC15_RS18040	COG0765	amino acid transport
CUC15_RS18045	COG0765	amino acid transport
CUC15_RS18050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC15_RS18055	COG1126	abc transporter atp-binding protein
CUC15_RS18060	COG4608	Belongs to the ABC transporter superfamily
CUC15_RS18065	COG0444	Belongs to the ABC transporter superfamily
CUC15_RS18070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUC15_RS18075	COG0601	transmembrane transport
CUC15_RS18080	COG4166	transmembrane transport
CUC15_RS18090	COG2070	2-Nitropropane dioxygenase
CUC15_RS18105	COG0577	efflux transmembrane transporter activity
CUC15_RS18110	COG1136	(ABC) transporter
CUC15_RS18115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC15_RS18120	COG2814	Major facilitator Superfamily
CUC15_RS18125	COG2032	superoxide dismutase activity
CUC15_RS18140	COG1725	Transcriptional regulator
CUC15_RS18150	COG4152	abc transporter atp-binding protein
CUC15_RS18165	COG3220	belongs to the UPF0276 family
CUC15_RS18170	COG0655	NAD(P)H dehydrogenase (quinone) activity
CUC15_RS18175	COG0860	N-Acetylmuramoyl-L-alanine amidase
CUC15_RS18180	COG0789	Transcriptional regulator
CUC15_RS18185	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUC15_RS18195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUC15_RS18200	COG0583	DNA-binding transcription factor activity
CUC15_RS18205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CUC15_RS18210	COG1125	glycine betaine transport
CUC15_RS18210	COG0517	IMP dehydrogenase activity
CUC15_RS18215	COG4120	Belongs to the binding-protein-dependent transport system permease family
CUC15_RS18235	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CUC15_RS18240	COG1408	metallophosphoesterase
CUC15_RS18250	COG1132	(ABC) transporter
CUC15_RS18300	COG5039	Polysaccharide pyruvyl transferase
CUC15_RS18305	COG1132	(ABC) transporter
CUC15_RS18310	COG1442	glycosyl transferase family 8
CUC15_RS18310	COG1216	Glycosyl transferase, family 2
CUC15_RS18315	COG1216	Glycosyl transferase, family 2
CUC15_RS18330	COG1216	Glycosyl transferase, family 2
CUC15_RS18330	COG1442	glycosyl transferase family 8
CUC15_RS18335	COG0438	transferase activity, transferring glycosyl groups
CUC15_RS18340	COG0438	transferase activity, transferring glycosyl groups
CUC15_RS18350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CUC15_RS18355	COG0110	maltose O-acetyltransferase activity
CUC15_RS18360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CUC15_RS18365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUC15_RS18375	COG1442	glycosyl transferase family 8
CUC15_RS18375	COG1216	Glycosyl transferase, family 2
CUC15_RS18380	COG0438	transferase activity, transferring glycosyl groups
CUC15_RS18385	COG0438	transferase activity, transferring glycosyl groups
CUC15_RS18390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CUC15_RS18395	COG1086	Polysaccharide biosynthesis protein
CUC15_RS18400	COG0489	protein tyrosine kinase activity
CUC15_RS18410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC15_RS18415	COG1320	monovalent cation:proton antiporter activity
CUC15_RS18420	COG2212	antiporter activity
CUC15_RS18425	COG1863	multisubunit Na H antiporter MnhE subunit
CUC15_RS18430	COG0651	ATP synthesis coupled electron transport
CUC15_RS18435	COG1006	Multisubunit Na H antiporter MnhC subunit
CUC15_RS18440	COG2111	Na H antiporter
CUC15_RS18445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CUC15_RS18445	COG2111	Na H antiporter
CUC15_RS18460	COG2197	response regulator
CUC15_RS18465	COG4585	Histidine kinase
CUC15_RS18470	COG3239	Fatty acid desaturase
CUC15_RS18490	COG0039	L-malate dehydrogenase activity
CUC15_RS18495	COG1199	ATP-dependent helicase activity
CUC15_RS18500	COG2223	nitrite transmembrane transporter activity
CUC15_RS18510	COG1252	NADH dehydrogenase
CUC15_RS18520	COG2723	6-phospho-beta-galactosidase activity
CUC15_RS18525	COG1263	PTS System
CUC15_RS18525	COG2190	(PTS) system
CUC15_RS18525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUC15_RS18530	COG3711	transcriptional antiterminator
CUC15_RS18535	COG0561	phosphatase activity
CUC15_RS18540	COG4166	transmembrane transport
CUC15_RS18545	COG0165	Argininosuccinate lyase
CUC15_RS18550	COG0137	argininosuccinate synthase activity
CUC15_RS18555	COG0702	epimerase
CUC15_RS18560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CUC15_RS18565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CUC15_RS18575	COG0573	inorganic phosphate transmembrane transporter activity
CUC15_RS18580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CUC15_RS18585	COG1380	Effector of murein hydrolase LrgA
CUC15_RS18590	COG1346	cytolysis
CUC15_RS18600	COG1368	sulfuric ester hydrolase activity
CUC15_RS18610	COG0693	protein deglycase activity
CUC15_RS18620	COG0667	Aldo Keto reductase
CUC15_RS18625	COG1902	pentaerythritol trinitrate reductase activity
CUC15_RS18630	COG3279	Response regulator of the LytR AlgR family
CUC15_RS18630	COG5000	phosphorelay sensor kinase activity
CUC15_RS18650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CUC15_RS18655	COG3104	oligopeptide transport
CUC15_RS18770	COG2340	Cysteine-rich secretory protein family
CUC15_RS18775	COG0133	tryptophan synthase activity
CUC15_RS18790	COG5337	Spore coat protein CotH
CUC15_RS18795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUC15_RS18800	COG3695	enzyme binding
CUC15_RS18820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CUC15_RS18825	COG0686	Belongs to the AlaDH PNT family
CUC15_RS18830	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CUC15_RS18830	COG2508	Transcriptional regulator
CUC15_RS18835	COG1115	amino acid carrier protein
CUC15_RS18840	COG3949	Membrane
CUC15_RS18855	COG1393	Belongs to the ArsC family
CUC15_RS18870	COG3842	ATPase activity
CUC15_RS18875	COG1176	ABC-type spermidine putrescine transport system, permease component I
CUC15_RS18880	COG1177	transmembrane transport
CUC15_RS18885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CUC15_RS18890	COG0326	Molecular chaperone. Has ATPase activity
CUC15_RS18895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CUC15_RS18900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CUC15_RS18905	COG1937	Protein conserved in bacteria
CUC15_RS18925	COG3639	organic phosphonate transmembrane transporter activity
CUC15_RS18930	COG3639	organic phosphonate transmembrane transporter activity
CUC15_RS18935	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CUC15_RS18945	COG0613	PHP domain protein
CUC15_RS18950	COG4778	phosphonate C-P lyase system protein PhnL
CUC15_RS18955	COG3454	Phosphonate metabolism
CUC15_RS18960	COG4107	phosphonate C-P lyase system protein PhnK
CUC15_RS18965	COG3627	carbon phosphorus lyase activity
CUC15_RS18985	COG2188	Transcriptional regulator
CUC15_RS18995	COG1376	ErfK ybiS ycfS ynhG family protein
CUC15_RS19005	COG2848	UPF0210 protein
CUC15_RS19010	COG3830	Belongs to the UPF0237 family
CUC15_RS19015	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CUC15_RS19030	COG0411	ABC transporter
CUC15_RS19055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUC15_RS19070	COG0217	transcriptional regulatory protein
CUC15_RS19080	COG1115	amino acid carrier protein
CUC15_RS19085	COG2076	Multidrug Resistance protein
CUC15_RS19090	COG2076	Multidrug Resistance protein
CUC15_RS19110	COG3275	phosphorelay sensor kinase activity
CUC15_RS19120	COG1966	Carbon starvation protein
CUC15_RS19135	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CUC15_RS19140	COG2824	Alkylphosphonate utilization operon protein PhnA
CUC15_RS19160	COG1408	metallophosphoesterase
CUC15_RS19170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUC15_RS19180	COG2814	Major facilitator Superfamily
CUC15_RS19185	COG1846	Transcriptional regulator
CUC15_RS19195	COG0579	oxidoreductase
CUC15_RS19220	COG3878	Protein conserved in bacteria
CUC15_RS19225	COG1113	amino acid transport
CUC15_RS19230	COG3835	regulator
CUC15_RS19235	COG1012	belongs to the aldehyde dehydrogenase family
CUC15_RS19240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CUC15_RS19250	COG2860	membrane
CUC15_RS19255	COG1136	(ABC) transporter
CUC15_RS19265	COG4708	membrane
CUC15_RS19270	COG1028	Short-chain dehydrogenase reductase Sdr
CUC15_RS19295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC15_RS19305	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CUC15_RS19330	COG1301	dicarboxylic acid transport
CUC15_RS19335	COG1523	belongs to the glycosyl hydrolase 13 family
CUC15_RS19345	COG2814	Major facilitator Superfamily
CUC15_RS19350	COG2197	response regulator
CUC15_RS19355	COG4585	Histidine kinase
CUC15_RS19355	COG2203	Gaf domain
CUC15_RS19405	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CUC15_RS19410	COG0697	spore germination
CUC15_RS19420	COG0402	S-adenosylhomocysteine deaminase activity
CUC15_RS19425	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CUC15_RS19430	COG1733	regulation of RNA biosynthetic process
CUC15_RS19435	COG2814	Major facilitator Superfamily
CUC15_RS19475	COG3829	transcription factor binding
CUC15_RS19475	COG3290	protein histidine kinase activity
CUC15_RS19510	COG0494	nUDIX hydrolase
CUC15_RS19525	COG0737	Belongs to the 5'-nucleotidase family
CUC15_RS19525	COG1525	nuclease
CUC15_RS19525	COG4085	toxin activity
CUC15_RS19530	COG0405	Gamma-glutamyltransferase
CUC15_RS19535	COG1454	alcohol dehydrogenase
CUC15_RS19540	COG1012	belongs to the aldehyde dehydrogenase family
CUC15_RS19545	COG1510	regulation of RNA biosynthetic process
CUC15_RS19555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CUC15_RS19565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUC15_RS19590	COG1472	Belongs to the glycosyl hydrolase 3 family
CUC15_RS19595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CUC15_RS19630	COG2197	response regulator
CUC15_RS19635	COG4585	Histidine kinase
CUC15_RS19645	COG1126	abc transporter atp-binding protein
CUC15_RS19650	COG0765	amino acid transport
CUC15_RS19655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC15_RS19665	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CUC15_RS19680	COG0831	urea catabolic process
CUC15_RS19685	COG0028	Belongs to the TPP enzyme family
CUC15_RS19690	COG0318	PFAM AMP-dependent synthetase and ligase
CUC15_RS19710	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CUC15_RS19720	COG2270	Major facilitator Superfamily
CUC15_RS19730	COG0662	Cupin 2, conserved barrel domain protein
CUC15_RS19740	COG2027	D-alanyl-D-alanine carboxypeptidase
CUC15_RS19745	COG1476	TRANSCRIPTIONal
CUC15_RS19760	COG1366	Belongs to the anti-sigma-factor antagonist family
CUC15_RS19765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUC15_RS19775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUC15_RS19785	COG0406	alpha-ribazole phosphatase activity
CUC15_RS19790	COG0483	inositol monophosphate 1-phosphatase activity
CUC15_RS19800	COG1132	(ABC) transporter
CUC15_RS19805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC15_RS19810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CUC15_RS19815	COG4853	Protein conserved in bacteria
CUC15_RS19820	COG4863	YycH protein
CUC15_RS19825	COG5002	protein histidine kinase activity
CUC15_RS19830	COG0745	RESPONSE REGULATOR receiver
CUC15_RS19835	COG1196	nuclear chromosome segregation
CUC15_RS19835	COG0739	heme binding
CUC15_RS19835	COG0741	lytic transglycosylase activity
CUC15_RS19845	COG0305	Participates in initiation and elongation during chromosome replication
CUC15_RS19850	COG0359	binds to the 23S rRNA
CUC15_RS19855	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CUC15_RS19870	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CUC15_RS19875	COG0629	single-stranded DNA binding
CUC15_RS19880	COG0360	Binds together with S18 to 16S ribosomal RNA
CUC15_RS19885	COG0012	GTP binding
CUC15_RS19890	COG4481	Protein conserved in bacteria
CUC15_RS19900	COG3949	Membrane
CUC15_RS19910	COG1811	Na channel or pump
CUC15_RS19915	COG1475	DNA binding
CUC15_RS19920	COG1192	Involved in chromosome partitioning
CUC15_RS19925	COG1475	DNA binding
CUC15_RS19930	COG0357	Ribosomal RNA small subunit methyltransferase G
CUC15_RS19935	COG0445	tRNA wobble uridine modification
CUC15_RS19940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CUC15_RS19950	COG1847	R3H domain protein
CUC15_RS19955	COG0706	membrane insertase activity
CUC15_RS19960	COG0594	ribonuclease P activity
CUC15_RS19965	COG0230	Belongs to the bacterial ribosomal protein bL34 family