locus-tag	class	description
OEOE_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OEOE_RS00010	COG0592	DNA-directed DNA polymerase activity
OEOE_RS00015	COG2501	S4 domain
OEOE_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OEOE_RS00025	COG0187	DNA topoisomerase II activity
OEOE_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OEOE_RS00040	COG2132	Multicopper oxidase
OEOE_RS00045	COG0360	Binds together with S18 to 16S ribosomal RNA
OEOE_RS00050	COG0629	single-stranded DNA binding
OEOE_RS00055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OEOE_RS00065	COG0359	binds to the 23S rRNA
OEOE_RS00070	COG0305	Participates in initiation and elongation during chromosome replication
OEOE_RS00090	COG1490	D-aminoacyl-tRNA deacylase activity
OEOE_RS00095	COG3842	ATPase activity
OEOE_RS00115	COG3579	cysteine-type endopeptidase activity
OEOE_RS00120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OEOE_RS00135	COG0114	fumarate hydratase activity
OEOE_RS00140	COG1131	(ABC) transporter
OEOE_RS00165	COG0667	Aldo Keto reductase
OEOE_RS00175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OEOE_RS00185	COG0366	Alpha amylase catalytic
OEOE_RS00205	COG4221	oxidoreductase activity
OEOE_RS00210	COG1309	transcriptional regulator
OEOE_RS00225	COG2814	Major facilitator Superfamily
OEOE_RS00230	COG0673	inositol 2-dehydrogenase activity
OEOE_RS00250	COG2261	transglycosylase associated protein
OEOE_RS00305	COG1028	Short-chain dehydrogenase reductase Sdr
OEOE_RS00315	COG2261	transglycosylase associated protein
OEOE_RS00325	COG5039	Polysaccharide pyruvyl transferase
OEOE_RS00340	COG2814	Major facilitator Superfamily
OEOE_RS00345	COG2814	Major facilitator Superfamily
OEOE_RS00350	COG1028	Short-chain dehydrogenase reductase Sdr
OEOE_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
OEOE_RS00360	COG0789	Transcriptional regulator
OEOE_RS00365	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OEOE_RS00425	COG0551	DNA topoisomerase type I activity
OEOE_RS00425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OEOE_RS00450	COG0572	uridine kinase
OEOE_RS00485	COG0745	RESPONSE REGULATOR receiver
OEOE_RS00490	COG5002	protein histidine kinase activity
OEOE_RS00495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OEOE_RS00500	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OEOE_RS00510	COG0628	permease
OEOE_RS00515	COG0357	Ribosomal RNA small subunit methyltransferase G
OEOE_RS00520	COG1192	Involved in chromosome partitioning
OEOE_RS00530	COG1475	DNA binding
OEOE_RS00535	COG4481	Protein conserved in bacteria
OEOE_RS00540	COG0012	GTP binding
OEOE_RS00550	COG0745	RESPONSE REGULATOR receiver
OEOE_RS00560	COG1686	Belongs to the peptidase S11 family
OEOE_RS00565	COG0588	phosphoglycerate mutase activity
OEOE_RS00575	COG4708	membrane
OEOE_RS00605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OEOE_RS00635	COG1253	flavin adenine dinucleotide binding
OEOE_RS00645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OEOE_RS00650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OEOE_RS00655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OEOE_RS00660	COG0745	RESPONSE REGULATOR receiver
OEOE_RS00665	COG5002	protein histidine kinase activity
OEOE_RS00680	COG1609	Transcriptional regulator
OEOE_RS00690	COG0738	Major facilitator superfamily
OEOE_RS00700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OEOE_RS00705	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OEOE_RS00715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OEOE_RS00720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OEOE_RS00730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OEOE_RS00735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OEOE_RS00740	COG0667	Aldo Keto reductase
OEOE_RS00745	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OEOE_RS00755	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OEOE_RS00765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OEOE_RS00770	COG0492	ferredoxin-NADP+ reductase activity
OEOE_RS00775	COG1956	GAF domain-containing protein
OEOE_RS00780	COG1368	sulfuric ester hydrolase activity
OEOE_RS00795	COG1254	Belongs to the acylphosphatase family
OEOE_RS00800	COG2814	Major facilitator Superfamily
OEOE_RS00820	COG1129	ABC transporter
OEOE_RS00825	COG4721	ABC-type cobalt transport system, permease component
OEOE_RS00830	COG4721	ABC-type cobalt transport system, permease component
OEOE_RS00835	COG0564	pseudouridine synthase activity
OEOE_RS00850	COG1309	transcriptional regulator
OEOE_RS00855	COG1511	domain protein
OEOE_RS00865	COG0193	aminoacyl-tRNA hydrolase activity
OEOE_RS00870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OEOE_RS00875	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OEOE_RS00885	COG0037	tRNA processing
OEOE_RS00890	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OEOE_RS00900	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OEOE_RS00905	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OEOE_RS00915	COG2814	Major facilitator Superfamily
OEOE_RS00945	COG0577	efflux transmembrane transporter activity
OEOE_RS00945	COG1136	(ABC) transporter
OEOE_RS00950	COG0577	efflux transmembrane transporter activity
OEOE_RS00950	COG1136	(ABC) transporter
OEOE_RS00975	COG1131	(ABC) transporter
OEOE_RS00985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OEOE_RS00995	COG2169	Transcriptional regulator
OEOE_RS01015	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OEOE_RS01025	COG1063	alcohol dehydrogenase
OEOE_RS01030	COG0463	Glycosyl transferase, family 2
OEOE_RS01045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OEOE_RS01050	COG1447	Phosphotransferase system cellobiose-specific component IIA
OEOE_RS01055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OEOE_RS01060	COG2723	6-phospho-beta-galactosidase activity
OEOE_RS01100	COG2017	converts alpha-aldose to the beta-anomer
OEOE_RS01120	COG3775	system Galactitol-specific IIC component
OEOE_RS01140	COG2873	o-acetylhomoserine
OEOE_RS01150	COG2267	carboxylic ester hydrolase activity
OEOE_RS01160	COG0667	Aldo Keto reductase
OEOE_RS01170	COG1309	transcriptional regulator
OEOE_RS01180	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OEOE_RS01190	COG1482	cell wall glycoprotein biosynthetic process
OEOE_RS01220	COG0395	ABC-type sugar transport system, permease component
OEOE_RS01225	COG1609	Transcriptional regulator
OEOE_RS01235	COG0540	Belongs to the ATCase OTCase family
OEOE_RS01240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OEOE_RS01245	COG0505	Belongs to the CarA family
OEOE_RS01250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OEOE_RS01255	COG0284	orotidine-5'-phosphate decarboxylase activity
OEOE_RS01265	COG0167	dihydroorotate dehydrogenase activity
OEOE_RS01270	COG2814	Major facilitator Superfamily
OEOE_RS01275	COG2084	Dehydrogenase
OEOE_RS01285	COG4120	Belongs to the binding-protein-dependent transport system permease family
OEOE_RS01290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OEOE_RS01290	COG1116	anion transmembrane transporter activity
OEOE_RS01295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OEOE_RS01325	COG1136	(ABC) transporter
OEOE_RS01325	COG0577	efflux transmembrane transporter activity
OEOE_RS01330	COG2050	protein possibly involved in aromatic compounds catabolism
OEOE_RS01335	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OEOE_RS01340	COG0318	PFAM AMP-dependent synthetase and ligase
OEOE_RS01350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OEOE_RS01370	COG1696	Membrane protein involved in D-alanine export
OEOE_RS01375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OEOE_RS01380	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OEOE_RS01385	COG0071	Belongs to the small heat shock protein (HSP20) family
OEOE_RS01390	COG0477	Major facilitator Superfamily
OEOE_RS01415	COG1263	PTS System
OEOE_RS01415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OEOE_RS01415	COG2190	(PTS) system
OEOE_RS01420	COG2190	(PTS) system
OEOE_RS01420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OEOE_RS01420	COG1263	PTS System
OEOE_RS01425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OEOE_RS01425	COG1263	PTS System
OEOE_RS01425	COG2190	(PTS) system
OEOE_RS01435	COG2017	converts alpha-aldose to the beta-anomer
OEOE_RS01440	COG1609	Transcriptional regulator
OEOE_RS01445	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OEOE_RS01450	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OEOE_RS01455	COG2190	(PTS) system
OEOE_RS01455	COG2211	Major facilitator Superfamily
OEOE_RS01470	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OEOE_RS01475	COG1074	ATP-dependent DNA helicase activity
OEOE_RS01480	COG0588	phosphoglycerate mutase activity
OEOE_RS01490	COG0519	Catalyzes the synthesis of GMP from XMP
OEOE_RS01495	COG0628	permease
OEOE_RS01510	COG0756	dUTP diphosphatase activity
OEOE_RS01515	COG0494	nUDIX hydrolase
OEOE_RS01520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OEOE_RS01525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OEOE_RS01530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OEOE_RS01535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OEOE_RS01550	COG1012	belongs to the aldehyde dehydrogenase family
OEOE_RS01565	COG0095	Lipoate-protein ligase
OEOE_RS01595	COG0436	Aminotransferase
OEOE_RS01610	COG0551	DNA topoisomerase type I activity
OEOE_RS01610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OEOE_RS01615	COG0561	phosphatase activity
OEOE_RS01620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OEOE_RS01625	COG1447	Phosphotransferase system cellobiose-specific component IIA
OEOE_RS01630	COG2723	6-phospho-beta-galactosidase activity
OEOE_RS01635	COG2723	6-phospho-beta-galactosidase activity
OEOE_RS01645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OEOE_RS01660	COG2801	Transposase and inactivated derivatives
OEOE_RS01665	COG2217	Heavy metal translocating P-type atpase
OEOE_RS01670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OEOE_RS01675	COG3118	belongs to the thioredoxin family
OEOE_RS01680	COG1937	Protein conserved in bacteria
OEOE_RS01700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OEOE_RS01730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OEOE_RS01730	COG0551	DNA topoisomerase type I activity
OEOE_RS01760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OEOE_RS01765	COG1335	isochorismatase
OEOE_RS01770	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OEOE_RS01780	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
OEOE_RS01785	COG0556	nucleotide-excision repair
OEOE_RS01795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OEOE_RS01805	COG2233	PERMEase
OEOE_RS01815	COG0860	N-Acetylmuramoyl-L-alanine amidase
OEOE_RS01815	COG3103	Sh3 type 3 domain protein
OEOE_RS01815	COG4991	sh3 domain protein
OEOE_RS01820	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OEOE_RS01830	COG3716	PTS system mannose fructose sorbose family IID component
OEOE_RS01840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OEOE_RS01865	COG0531	amino acid
OEOE_RS01895	COG1063	alcohol dehydrogenase
OEOE_RS01900	COG1309	transcriptional regulator
OEOE_RS01905	COG1028	Short-chain dehydrogenase reductase Sdr
OEOE_RS01915	COG0488	(ABC) transporter
OEOE_RS01920	COG1121	(ABC) transporter
OEOE_RS01950	COG2246	polysaccharide biosynthetic process
OEOE_RS01960	COG0673	inositol 2-dehydrogenase activity
OEOE_RS01975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OEOE_RS01980	COG0583	DNA-binding transcription factor activity
OEOE_RS01985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OEOE_RS01990	COG4988	ABC transporter
OEOE_RS01995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OEOE_RS02000	COG1705	Flagellar rod assembly protein muramidase FlgJ
OEOE_RS02005	COG2390	Transcriptional regulator
OEOE_RS02025	COG3052	prosthetic group binding
OEOE_RS02040	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
OEOE_RS02040	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OEOE_RS02055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OEOE_RS02065	COG0779	Required for maturation of 30S ribosomal subunits
OEOE_RS02070	COG0195	Participates in both transcription termination and antitermination
OEOE_RS02075	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OEOE_RS02085	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OEOE_RS02090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OEOE_RS02095	COG1316	TRANSCRIPTIONal
OEOE_RS02105	COG1428	Deoxynucleoside kinase
OEOE_RS02115	COG1136	(ABC) transporter
OEOE_RS02120	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OEOE_RS02125	COG1809	phosphosulfolactate synthase activity
OEOE_RS02135	COG1114	Component of the transport system for branched-chain amino acids
OEOE_RS02145	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OEOE_RS02155	COG1461	Dihydroxyacetone kinase
OEOE_RS02160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OEOE_RS02165	COG0416	fatty acid biosynthetic process
OEOE_RS02170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OEOE_RS02180	COG0571	ribonuclease III activity
OEOE_RS02185	COG1196	nuclear chromosome segregation
OEOE_RS02190	COG0552	protein localization to endoplasmic reticulum
OEOE_RS02200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OEOE_RS02205	COG1193	negative regulation of DNA recombination
OEOE_RS02210	COG0716	FMN binding
OEOE_RS02215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OEOE_RS02235	COG3715	PTS system
OEOE_RS02240	COG3716	PTS system mannose fructose sorbose family IID component
OEOE_RS02250	COG1619	proteins homologs of microcin C7 resistance protein MccF
OEOE_RS02270	COG1136	(ABC) transporter
OEOE_RS02270	COG0577	efflux transmembrane transporter activity
OEOE_RS02280	COG2814	Major facilitator Superfamily
OEOE_RS02290	COG0640	Transcriptional regulator
OEOE_RS02310	COG0586	Pfam SNARE associated Golgi protein
OEOE_RS02320	COG0463	Glycosyl transferase, family 2
OEOE_RS02330	COG0745	RESPONSE REGULATOR receiver
OEOE_RS02335	COG5002	protein histidine kinase activity
OEOE_RS02335	COG3850	Histidine kinase
OEOE_RS02350	COG0633	Ferredoxin
OEOE_RS02350	COG0543	2 iron, 2 sulfur cluster binding
OEOE_RS02355	COG2244	polysaccharide biosynthetic process
OEOE_RS02400	COG0477	Major facilitator Superfamily
OEOE_RS02415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OEOE_RS02425	COG0667	Aldo Keto reductase
OEOE_RS02440	COG4463	regulation of RNA biosynthetic process
OEOE_RS02445	COG0542	response to heat
OEOE_RS02455	COG1902	pentaerythritol trinitrate reductase activity
OEOE_RS02460	COG0488	(ABC) transporter
OEOE_RS02465	COG0656	L-ascorbic acid biosynthetic process
OEOE_RS02485	COG1695	Transcriptional regulator
OEOE_RS02510	COG1064	alcohol dehydrogenase
OEOE_RS02520	COG0183	Belongs to the thiolase family
OEOE_RS02545	COG0516	GMP reductase activity
OEOE_RS02555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OEOE_RS02575	COG1132	(ABC) transporter
OEOE_RS02580	COG0366	Alpha amylase catalytic
OEOE_RS02580	COG5263	repeat protein
OEOE_RS02610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OEOE_RS02615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OEOE_RS02635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OEOE_RS02650	COG0573	inorganic phosphate transmembrane transporter activity
OEOE_RS02655	COG0581	inorganic phosphate transmembrane transporter activity
OEOE_RS02660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OEOE_RS02665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OEOE_RS02670	COG0704	Plays a role in the regulation of phosphate uptake
OEOE_RS02680	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OEOE_RS02685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OEOE_RS02690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OEOE_RS02695	COG0492	ferredoxin-NADP+ reductase activity
OEOE_RS02700	COG1660	Displays ATPase and GTPase activities
OEOE_RS02705	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OEOE_RS02710	COG1481	regulation of sporulation
OEOE_RS02715	COG0740	serine-type endopeptidase activity
OEOE_RS02735	COG0006	proline dipeptidase activity
OEOE_RS02750	COG0632	four-way junction helicase activity
OEOE_RS02755	COG2255	four-way junction helicase activity
OEOE_RS02760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OEOE_RS02765	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
OEOE_RS02770	COG0481	GTPase activity
OEOE_RS02785	COG0604	alcohol dehydrogenase
OEOE_RS02790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OEOE_RS02800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OEOE_RS02805	COG0860	N-Acetylmuramoyl-L-alanine amidase
OEOE_RS02815	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OEOE_RS02820	COG2755	lipolytic protein G-D-S-L family
OEOE_RS02820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OEOE_RS02830	COG2755	lipolytic protein G-D-S-L family
OEOE_RS02830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OEOE_RS02840	COG0051	transcription antitermination factor activity, RNA binding
OEOE_RS02845	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OEOE_RS02850	COG0088	Forms part of the polypeptide exit tunnel
OEOE_RS02855	COG0089	rRNA binding
OEOE_RS02860	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OEOE_RS02865	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OEOE_RS02870	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OEOE_RS02875	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OEOE_RS02880	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OEOE_RS02885	COG0255	Belongs to the universal ribosomal protein uL29 family
OEOE_RS02890	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OEOE_RS02895	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OEOE_RS02900	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OEOE_RS02905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OEOE_RS02910	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OEOE_RS02915	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OEOE_RS02920	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OEOE_RS02925	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OEOE_RS02930	COG1841	ribosomal large subunit assembly
OEOE_RS02935	COG0200	Binds to the 23S rRNA
OEOE_RS02945	COG0563	adenylate kinase activity
OEOE_RS02950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OEOE_RS02955	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OEOE_RS02960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OEOE_RS02965	COG0202	RNA polymerase activity
OEOE_RS02970	COG0203	ribosomal protein L17
OEOE_RS02975	COG1122	ATPase activity
OEOE_RS02990	COG0101	tRNA pseudouridine synthase activity
OEOE_RS03000	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OEOE_RS03005	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OEOE_RS03010	COG3842	ATPase activity
OEOE_RS03015	COG1176	ABC-type spermidine putrescine transport system, permease component I
OEOE_RS03025	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OEOE_RS03030	COG0697	spore germination
OEOE_RS03035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OEOE_RS03040	COG0166	Belongs to the GPI family
OEOE_RS03045	COG0393	Putative heavy-metal-binding
OEOE_RS03050	COG0126	phosphoglycerate kinase activity
OEOE_RS03060	COG0542	response to heat
OEOE_RS03075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OEOE_RS03080	COG0363	glucosamine-6-phosphate deaminase activity
OEOE_RS03090	COG0561	phosphatase activity
OEOE_RS03095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OEOE_RS03100	COG0438	transferase activity, transferring glycosyl groups
OEOE_RS03120	COG1368	sulfuric ester hydrolase activity
OEOE_RS03145	COG3048	D-serine ammonia-lyase activity
OEOE_RS03150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OEOE_RS03155	COG0356	it plays a direct role in the translocation of protons across the membrane
OEOE_RS03160	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OEOE_RS03165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OEOE_RS03170	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OEOE_RS03175	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OEOE_RS03180	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OEOE_RS03185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OEOE_RS03190	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OEOE_RS03200	COG1077	Cell shape determining protein MreB Mrl
OEOE_RS03210	COG0772	Belongs to the SEDS family
OEOE_RS03220	COG1181	Belongs to the D-alanine--D-alanine ligase family
OEOE_RS03225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OEOE_RS03225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OEOE_RS03240	COG0237	dephospho-CoA kinase activity
OEOE_RS03250	COG1484	DNA-dependent DNA replication
OEOE_RS03260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OEOE_RS03265	COG0622	Phosphoesterase
OEOE_RS03360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OEOE_RS03370	COG0300	oxidoreductase activity
OEOE_RS03425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OEOE_RS03435	COG1686	Belongs to the peptidase S11 family
OEOE_RS03455	COG3279	Response regulator of the LytR AlgR family
OEOE_RS03465	COG1376	ErfK ybiS ycfS ynhG family protein
OEOE_RS03490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OEOE_RS03495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OEOE_RS03510	COG1136	(ABC) transporter
OEOE_RS03525	COG1131	(ABC) transporter
OEOE_RS03535	COG1285	pathogenesis
OEOE_RS03560	COG1063	alcohol dehydrogenase
OEOE_RS03590	COG1126	abc transporter atp-binding protein
OEOE_RS03595	COG0765	amino acid transport
OEOE_RS03605	COG2364	Membrane
OEOE_RS03620	COG2855	membrane
OEOE_RS03625	COG0300	oxidoreductase activity
OEOE_RS03660	COG0626	cystathionine gamma-synthase activity
OEOE_RS03665	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OEOE_RS03670	COG0217	transcriptional regulatory protein
OEOE_RS03675	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OEOE_RS03680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OEOE_RS03690	COG0019	diaminopimelate decarboxylase activity
OEOE_RS03695	COG2171	N-acyltransferase activity
OEOE_RS03700	COG1473	amidohydrolase
OEOE_RS03705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OEOE_RS03710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OEOE_RS03715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OEOE_RS03720	COG0436	Aminotransferase
OEOE_RS03725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OEOE_RS03730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OEOE_RS03735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OEOE_RS03745	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OEOE_RS03750	COG2252	PERMEase
OEOE_RS03760	COG0737	Belongs to the 5'-nucleotidase family
OEOE_RS03765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OEOE_RS03770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OEOE_RS03780	COG2815	serine threonine protein kinase
OEOE_RS03780	COG0515	serine threonine protein kinase
OEOE_RS03785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OEOE_RS03795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OEOE_RS03805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OEOE_RS03825	COG0228	four-way junction DNA binding
OEOE_RS03835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OEOE_RS03840	COG0336	Belongs to the RNA methyltransferase TrmD family
OEOE_RS03855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OEOE_RS03860	COG1942	4-Oxalocrotonate Tautomerase
OEOE_RS03875	COG1217	gtp-binding protein TYPA
OEOE_RS03880	COG1609	Transcriptional regulator
OEOE_RS03915	COG0561	phosphatase activity
OEOE_RS03930	COG1694	Mazg nucleotide pyrophosphohydrolase
OEOE_RS03935	COG2807	transmembrane transport
OEOE_RS03940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OEOE_RS03980	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OEOE_RS03985	COG1122	ATPase activity
OEOE_RS04010	COG0456	acetyltransferase
OEOE_RS04020	COG0561	phosphatase activity
OEOE_RS04030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OEOE_RS04035	COG0495	leucyl-tRNA aminoacylation
OEOE_RS04040	COG4166	transmembrane transport
OEOE_RS04045	COG4166	transmembrane transport
OEOE_RS04050	COG0601	transmembrane transport
OEOE_RS04055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OEOE_RS04060	COG0444	Belongs to the ABC transporter superfamily
OEOE_RS04065	COG4608	Belongs to the ABC transporter superfamily
OEOE_RS04070	COG2244	polysaccharide biosynthetic process
OEOE_RS04075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OEOE_RS04080	COG1968	undecaprenyl-diphosphatase activity
OEOE_RS04085	COG1428	Deoxynucleoside kinase
OEOE_RS04090	COG1970	mechanosensitive ion channel activity
OEOE_RS04120	COG3237	CsbD-like
OEOE_RS04190	COG0431	NADPH-dependent FMN reductase
OEOE_RS04200	COG2814	Major facilitator Superfamily
OEOE_RS04215	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OEOE_RS04220	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OEOE_RS04230	COG0531	amino acid
OEOE_RS04235	COG3275	phosphorelay sensor kinase activity
OEOE_RS04240	COG3279	Response regulator of the LytR AlgR family
OEOE_RS04245	COG2223	nitrite transmembrane transporter activity
OEOE_RS04255	COG0386	Belongs to the glutathione peroxidase family
OEOE_RS04260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OEOE_RS04265	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OEOE_RS04275	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OEOE_RS04280	COG1704	LemA family
OEOE_RS04285	COG0436	Aminotransferase
OEOE_RS04290	COG0436	Aminotransferase
OEOE_RS04295	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OEOE_RS04310	COG0018	arginyl-trna synthetase
OEOE_RS04315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OEOE_RS04320	COG3679	Belongs to the UPF0342 family
OEOE_RS04325	COG0420	3'-5' exonuclease activity
OEOE_RS04330	COG4717	serine-type aminopeptidase activity
OEOE_RS04335	COG3481	metal-dependent phosphohydrolase, HD sub domain
OEOE_RS04340	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OEOE_RS04345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OEOE_RS04350	COG1534	Rna-binding protein
OEOE_RS04355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OEOE_RS04360	COG1713	HD superfamily hydrolase involved in NAD metabolism
OEOE_RS04365	COG0799	negative regulation of ribosome biogenesis
OEOE_RS04370	COG2226	methyltransferase
OEOE_RS04375	COG1323	Belongs to the UPF0348 family
OEOE_RS04385	COG0706	membrane insertase activity
OEOE_RS04390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OEOE_RS04400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OEOE_RS04405	COG0072	phenylalanine-tRNA ligase activity
OEOE_RS04410	COG0705	Rhomboid family
OEOE_RS04415	COG1940	carbohydrate kinase activity
OEOE_RS04440	COG0640	Transcriptional regulator
OEOE_RS04480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OEOE_RS04485	COG0028	Belongs to the TPP enzyme family
OEOE_RS04490	COG2814	Major facilitator Superfamily
OEOE_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
OEOE_RS04500	COG0137	argininosuccinate synthase activity
OEOE_RS04505	COG0165	Argininosuccinate lyase
OEOE_RS04515	COG1307	EDD domain protein, DegV family
OEOE_RS04520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OEOE_RS04525	COG3830	Belongs to the UPF0237 family
OEOE_RS04530	COG2848	UPF0210 protein
OEOE_RS04535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OEOE_RS04540	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OEOE_RS04545	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OEOE_RS04550	COG0584	glycerophosphoryl diester phosphodiesterase
OEOE_RS04555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OEOE_RS04560	COG0789	Transcriptional regulator
OEOE_RS04565	COG0174	glutamine synthetase
OEOE_RS04590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OEOE_RS04595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OEOE_RS04600	COG0006	proline dipeptidase activity
OEOE_RS04615	COG1596	polysaccharide export
OEOE_RS04615	COG1555	photosystem II stabilization
OEOE_RS04625	COG2333	competence protein COMEC
OEOE_RS04625	COG0658	competence protein
OEOE_RS04645	COG3425	synthase
OEOE_RS04655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OEOE_RS04660	COG4224	UPF0291 protein
OEOE_RS04665	COG3763	UPF0154 protein
OEOE_RS04670	COG0204	Acyl-transferase
OEOE_RS04675	COG2827	Endonuclease containing a URI domain
OEOE_RS04680	COG0052	Belongs to the universal ribosomal protein uS2 family
OEOE_RS04685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OEOE_RS04690	COG0528	UMP kinase activity
OEOE_RS04695	COG0233	cytoplasmic translational termination
OEOE_RS04700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OEOE_RS04705	COG4589	Belongs to the CDS family
OEOE_RS04715	COG0442	prolyl-tRNA aminoacylation
OEOE_RS04720	COG2176	DNA-directed DNA polymerase activity
OEOE_RS04725	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OEOE_RS04730	COG1610	YqeY-like protein
OEOE_RS04735	COG1702	phosphate starvation-inducible protein PhoH
OEOE_RS04740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OEOE_RS04745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OEOE_RS04750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OEOE_RS04755	COG1381	Involved in DNA repair and RecF pathway recombination
OEOE_RS04765	COG0752	glycyl-tRNA synthetase alpha subunit
OEOE_RS04775	COG0751	glycine-tRNA ligase activity
OEOE_RS04780	COG0358	DNA primase activity
OEOE_RS04785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OEOE_RS04805	COG0587	DNA-directed DNA polymerase activity
OEOE_RS04815	COG4974	Belongs to the 'phage' integrase family
OEOE_RS04825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OEOE_RS04830	COG1187	pseudouridine synthase activity
OEOE_RS04835	COG1705	Flagellar rod assembly protein muramidase FlgJ
OEOE_RS04835	COG1388	LysM domain
OEOE_RS04840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OEOE_RS04845	COG1160	GTP binding
OEOE_RS04850	COG0776	regulation of translation
OEOE_RS04870	COG1307	EDD domain protein, DegV family
OEOE_RS04885	COG4479	Belongs to the UPF0346 family
OEOE_RS04895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OEOE_RS04900	COG0758	DNA mediated transformation
OEOE_RS04905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OEOE_RS04915	COG4974	Belongs to the 'phage' integrase family
OEOE_RS04925	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OEOE_RS04930	COG0187	DNA topoisomerase II activity
OEOE_RS04940	COG1227	inorganic diphosphatase activity
OEOE_RS04945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OEOE_RS04950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OEOE_RS04955	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OEOE_RS04960	COG2723	6-phospho-beta-galactosidase activity
OEOE_RS04965	COG0572	uridine kinase
OEOE_RS04970	COG3759	membrane
OEOE_RS04975	COG2261	transglycosylase associated protein
OEOE_RS04985	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OEOE_RS05005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OEOE_RS05005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OEOE_RS05015	COG3250	beta-galactosidase activity
OEOE_RS05020	COG0583	DNA-binding transcription factor activity
OEOE_RS05025	COG1902	pentaerythritol trinitrate reductase activity
OEOE_RS05035	COG1794	racemase activity, acting on amino acids and derivatives
OEOE_RS05050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OEOE_RS05065	COG2011	ABC-type metal ion transport system permease component
OEOE_RS05070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OEOE_RS05075	COG1956	GAF domain-containing protein
OEOE_RS05080	COG0308	aminopeptidase N
OEOE_RS05090	COG0330	HflC and HflK could
OEOE_RS05110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OEOE_RS05115	COG0596	Alpha beta hydrolase
OEOE_RS05120	COG1876	peptidase activity
OEOE_RS05140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OEOE_RS05145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OEOE_RS05145	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OEOE_RS05145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OEOE_RS05145	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OEOE_RS05150	COG1234	tRNA 3'-trailer cleavage
OEOE_RS05155	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OEOE_RS05160	COG0322	excinuclease ABC activity
OEOE_RS05175	COG1293	RNA-binding protein homologous to eukaryotic snRNP
OEOE_RS05185	COG0564	pseudouridine synthase activity
OEOE_RS05195	COG0116	Belongs to the methyltransferase superfamily
OEOE_RS05215	COG0142	geranyltranstransferase activity
OEOE_RS05220	COG1122	ATPase activity
OEOE_RS05225	COG1122	ATPase activity
OEOE_RS05250	COG4474	Belongs to the UPF0398 family
OEOE_RS05255	COG3331	DNA recombination
OEOE_RS05270	COG0017	Asparaginyl-tRNA synthetase
OEOE_RS05280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OEOE_RS05280	COG1199	ATP-dependent helicase activity
OEOE_RS05285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OEOE_RS05300	COG1304	FMN binding
OEOE_RS05305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OEOE_RS05305	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OEOE_RS05315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OEOE_RS05325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OEOE_RS05335	COG0822	iron-sulfur transferase activity
OEOE_RS05345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OEOE_RS05350	COG0719	Fe-S assembly protein
OEOE_RS05360	COG0602	queuosine metabolic process
OEOE_RS05370	COG2151	metal-sulfur cluster biosynthetic enzyme
OEOE_RS05375	COG2235	arginine
OEOE_RS05380	COG2252	PERMEase
OEOE_RS05385	COG0406	alpha-ribazole phosphatase activity
OEOE_RS05400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OEOE_RS05400	COG0519	Catalyzes the synthesis of GMP from XMP
OEOE_RS05405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OEOE_RS05410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OEOE_RS05415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OEOE_RS05420	COG0517	IMP dehydrogenase activity
OEOE_RS05420	COG0516	GMP reductase activity
OEOE_RS05430	COG0138	bifunctional purine biosynthesis protein purh
OEOE_RS05435	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OEOE_RS05450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OEOE_RS05455	COG0047	phosphoribosylformylglycinamidine synthase activity
OEOE_RS05460	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OEOE_RS05465	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OEOE_RS05470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OEOE_RS05475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OEOE_RS05480	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OEOE_RS05490	COG0762	integral membrane protein
OEOE_RS05495	COG1799	cell septum assembly
OEOE_RS05500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OEOE_RS05510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OEOE_RS05515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OEOE_RS05520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OEOE_RS05525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OEOE_RS05530	COG0768	penicillin binding
OEOE_RS05540	COG0275	rRNA processing
OEOE_RS05545	COG2001	Belongs to the MraZ family
OEOE_RS05555	COG1674	ftsk spoiiie
OEOE_RS05560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OEOE_RS05565	COG0628	permease
OEOE_RS05570	COG2706	6-phosphogluconolactonase activity
OEOE_RS05575	COG0564	pseudouridine synthase activity
OEOE_RS05580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OEOE_RS05585	COG1164	Oligoendopeptidase f
OEOE_RS05605	COG3906	Belongs to the UPF0473 family
OEOE_RS05610	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OEOE_RS05615	COG4472	Bacterial protein of unknown function (DUF965)
OEOE_RS05620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OEOE_RS05625	COG0531	amino acid
OEOE_RS05630	COG0589	response to stress
OEOE_RS05645	COG0163	prenyltransferase activity
OEOE_RS05650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OEOE_RS05655	COG0583	DNA-binding transcription factor activity
OEOE_RS05670	COG1131	(ABC) transporter
OEOE_RS05695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OEOE_RS05700	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
OEOE_RS05705	COG0583	DNA-binding transcription factor activity
OEOE_RS05710	COG1307	EDD domain protein, DegV family
OEOE_RS05715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OEOE_RS05730	COG0735	belongs to the Fur family
OEOE_RS05735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OEOE_RS05745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OEOE_RS05780	COG1705	Flagellar rod assembly protein muramidase FlgJ
OEOE_RS05795	COG5039	Polysaccharide pyruvyl transferase
OEOE_RS05815	COG1447	Phosphotransferase system cellobiose-specific component IIA
OEOE_RS05820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OEOE_RS05830	COG2723	6-phospho-beta-galactosidase activity
OEOE_RS05915	COG1098	S1 RNA binding domain
OEOE_RS05920	COG0586	Pfam SNARE associated Golgi protein
OEOE_RS05925	COG1758	RNA polymerase activity
OEOE_RS05940	COG0497	DNA recombination
OEOE_RS05955	COG1722	exodeoxyribonuclease VII activity
OEOE_RS05960	COG1570	exodeoxyribonuclease VII activity
OEOE_RS05965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OEOE_RS05975	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OEOE_RS05980	COG1611	Belongs to the LOG family
OEOE_RS05995	COG0768	penicillin binding
OEOE_RS06005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OEOE_RS06010	COG1705	Flagellar rod assembly protein muramidase FlgJ
OEOE_RS06015	COG1454	alcohol dehydrogenase
OEOE_RS06015	COG1012	belongs to the aldehyde dehydrogenase family
OEOE_RS06020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OEOE_RS06050	COG4537	Required for transformation and DNA binding
OEOE_RS06055	COG1459	type II secretion system
OEOE_RS06065	COG3480	Lon protease (S16) C-terminal proteolytic domain
OEOE_RS06070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OEOE_RS06075	COG0742	ribosomal rna small subunit methyltransferase
OEOE_RS06080	COG0772	Belongs to the SEDS family
OEOE_RS06085	COG0328	RNA-DNA hybrid ribonuclease activity
OEOE_RS06090	COG0318	PFAM AMP-dependent synthetase and ligase
OEOE_RS06105	COG0670	Belongs to the BI1 family
OEOE_RS06110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OEOE_RS06115	COG0072	phenylalanine-tRNA ligase activity
OEOE_RS06115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OEOE_RS06125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OEOE_RS06135	COG1131	(ABC) transporter
OEOE_RS06140	COG0537	adenosine 5'-monophosphoramidase activity
OEOE_RS06150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OEOE_RS06155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OEOE_RS06160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OEOE_RS06165	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OEOE_RS06180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OEOE_RS06185	COG0268	Binds directly to 16S ribosomal RNA
OEOE_RS06190	COG0513	Belongs to the DEAD box helicase family
OEOE_RS06195	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OEOE_RS06200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OEOE_RS06205	COG1862	Preprotein translocase
OEOE_RS06210	COG0343	queuine tRNA-ribosyltransferase activity
OEOE_RS06245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OEOE_RS06250	COG1846	Transcriptional regulator
OEOE_RS06260	COG1012	belongs to the aldehyde dehydrogenase family
OEOE_RS06270	COG0438	transferase activity, transferring glycosyl groups
OEOE_RS06280	COG0590	tRNA wobble adenosine to inosine editing
OEOE_RS06295	COG4946	Tricorn protease homolog
OEOE_RS06295	COG0823	Involved in the tonB-independent uptake of proteins
OEOE_RS06295	COG1506	peptidase
OEOE_RS06305	COG0484	heat shock protein binding
OEOE_RS06310	COG0443	Heat shock 70 kDa protein
OEOE_RS06315	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OEOE_RS06325	COG0196	riboflavin kinase activity
OEOE_RS06330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OEOE_RS06335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OEOE_RS06340	COG0049	tRNA binding
OEOE_RS06345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OEOE_RS06355	COG1739	Uncharacterized protein family UPF0029
OEOE_RS06365	COG0653	protein targeting
OEOE_RS06370	COG1040	competence protein
OEOE_RS06375	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OEOE_RS06395	COG0517	IMP dehydrogenase activity
OEOE_RS06405	COG0517	IMP dehydrogenase activity
OEOE_RS06405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OEOE_RS06410	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OEOE_RS06440	COG2188	Transcriptional regulator
OEOE_RS06445	COG0366	Alpha amylase catalytic
OEOE_RS06450	COG1263	PTS System
OEOE_RS06450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OEOE_RS06450	COG2190	(PTS) system
OEOE_RS06455	COG1263	PTS System
OEOE_RS06455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OEOE_RS06455	COG2190	(PTS) system
OEOE_RS06465	COG1132	(ABC) transporter
OEOE_RS06510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OEOE_RS06515	COG2261	transglycosylase associated protein
OEOE_RS06545	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OEOE_RS06550	COG3091	SprT-like family
OEOE_RS06570	COG0318	PFAM AMP-dependent synthetase and ligase
OEOE_RS06580	COG0351	phosphomethylpyrimidine kinase
OEOE_RS06610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OEOE_RS06615	COG0085	RNA polymerase activity
OEOE_RS06620	COG1278	Cold shock
OEOE_RS06630	COG2814	Major facilitator Superfamily
OEOE_RS06635	COG1132	(ABC) transporter
OEOE_RS06645	COG1272	protein, Hemolysin III
OEOE_RS06650	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OEOE_RS06655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OEOE_RS06660	COG1426	Protein conserved in bacteria
OEOE_RS06665	COG0612	Peptidase, M16
OEOE_RS06675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OEOE_RS06690	COG1077	Cell shape determining protein MreB Mrl
OEOE_RS06700	COG0525	valine-tRNA ligase activity
OEOE_RS06710	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OEOE_RS06715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OEOE_RS06725	COG0459	protein refolding
OEOE_RS06730	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OEOE_RS06735	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OEOE_RS06740	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OEOE_RS06750	COG1214	PFAM Peptidase M22, glycoprotease
OEOE_RS06755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OEOE_RS06770	COG0470	DNA polymerase III
OEOE_RS06775	COG3870	Protein conserved in bacteria
OEOE_RS06780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OEOE_RS06790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OEOE_RS06795	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OEOE_RS06805	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OEOE_RS06815	COG2813	Specifically methylates the guanine in position
OEOE_RS06825	COG0222	ribosome binding
OEOE_RS06830	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OEOE_RS06835	COG0081	regulation of translation
OEOE_RS06850	COG1070	Carbohydrate kinase
OEOE_RS06855	COG0250	Participates in transcription elongation, termination and antitermination
OEOE_RS06870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OEOE_RS06875	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OEOE_RS06880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OEOE_RS06885	COG0765	amino acid transport
OEOE_RS06890	COG1126	abc transporter atp-binding protein
OEOE_RS06910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OEOE_RS06915	COG0194	GDP metabolic process
OEOE_RS06920	COG0488	(ABC) transporter
OEOE_RS06930	COG0280	phosphate acetyltransferase
OEOE_RS06935	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OEOE_RS06945	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OEOE_RS06950	COG0557	exoribonuclease II activity
OEOE_RS06955	COG3973	AAA domain
OEOE_RS07000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OEOE_RS07010	COG1216	Glycosyl transferase, family 2
OEOE_RS07030	COG3842	ATPase activity
OEOE_RS07040	COG0395	ABC-type sugar transport system, permease component
OEOE_RS07050	COG0584	glycerophosphoryl diester phosphodiesterase
OEOE_RS07060	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OEOE_RS07070	COG3842	ATPase activity
OEOE_RS07075	COG1177	transmembrane transport
OEOE_RS07080	COG1176	ABC-type spermidine putrescine transport system, permease component I
OEOE_RS07085	COG2188	Transcriptional regulator
OEOE_RS07090	COG1397	ADP-ribosylglycohydrolase
OEOE_RS07100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OEOE_RS07115	COG1215	transferase activity, transferring glycosyl groups
OEOE_RS07130	COG1929	Belongs to the glycerate kinase type-1 family
OEOE_RS07135	COG2610	gluconate transmembrane transporter activity
OEOE_RS07140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OEOE_RS07160	COG3711	transcriptional antiterminator
OEOE_RS07165	COG4932	domain protein
OEOE_RS07165	COG4886	Leucine-rich repeat (LRR) protein
OEOE_RS07175	COG0531	amino acid
OEOE_RS07185	COG1122	ATPase activity
OEOE_RS07195	COG4721	ABC-type cobalt transport system, permease component
OEOE_RS07240	COG0110	maltose O-acetyltransferase activity
OEOE_RS07255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OEOE_RS07260	COG0489	protein tyrosine kinase activity
OEOE_RS07270	COG1917	Cupin 2, conserved barrel domain protein
OEOE_RS07270	COG4977	sequence-specific DNA binding
OEOE_RS07295	COG1215	transferase activity, transferring glycosyl groups
OEOE_RS07315	COG3706	GGDEF domain
OEOE_RS07335	COG1307	EDD domain protein, DegV family
OEOE_RS07340	COG1307	EDD domain protein, DegV family
OEOE_RS07345	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OEOE_RS07350	COG1737	Transcriptional regulator
OEOE_RS07385	COG3001	Fructosamine kinase
OEOE_RS07395	COG4152	abc transporter atp-binding protein
OEOE_RS07405	COG2814	Major facilitator Superfamily
OEOE_RS07415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OEOE_RS07425	COG1122	ATPase activity
OEOE_RS07435	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OEOE_RS07440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OEOE_RS07445	COG0527	aspartate kinase activity
OEOE_RS07450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OEOE_RS07455	COG0460	homoserine dehydrogenase
OEOE_RS07465	COG4466	Protein conserved in bacteria
OEOE_RS07470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OEOE_RS07480	COG0084	hydrolase, TatD family'
OEOE_RS07490	COG0656	L-ascorbic acid biosynthetic process
OEOE_RS07495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OEOE_RS07500	COG0095	Lipoate-protein ligase
OEOE_RS07515	COG0561	phosphatase activity
OEOE_RS07520	COG0215	cysteine-tRNA ligase activity
OEOE_RS07525	COG0300	oxidoreductase activity
OEOE_RS07535	COG1854	S-ribosylhomocysteine lyase activity
OEOE_RS07550	COG0583	DNA-binding transcription factor activity
OEOE_RS07570	COG1472	Belongs to the glycosyl hydrolase 3 family
OEOE_RS07590	COG0657	acetylesterase activity
OEOE_RS07605	COG1295	ribonuclease BN
OEOE_RS07615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OEOE_RS07620	COG0009	L-threonylcarbamoyladenylate synthase
OEOE_RS07625	COG2890	protein-(glutamine-N5) methyltransferase activity
OEOE_RS07635	COG0825	malonyl-CoA metabolic process
OEOE_RS07640	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OEOE_RS07645	COG0439	Biotin carboxylase
OEOE_RS07650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OEOE_RS07660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OEOE_RS07665	COG1028	Short-chain dehydrogenase reductase Sdr
OEOE_RS07685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OEOE_RS07695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OEOE_RS07700	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OEOE_RS07700	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OEOE_RS07705	COG1268	BioY protein
OEOE_RS07715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OEOE_RS07720	COG3442	glutamine amidotransferase
OEOE_RS07745	COG1744	ABC transporter substrate-binding protein PnrA-like
OEOE_RS07750	COG3845	ABC transporter
OEOE_RS07755	COG4603	Belongs to the binding-protein-dependent transport system permease family
OEOE_RS07760	COG1079	Belongs to the binding-protein-dependent transport system permease family
OEOE_RS07765	COG4166	transmembrane transport
OEOE_RS07780	COG1869	D-ribose catabolic process
OEOE_RS07785	COG0738	Major facilitator superfamily
OEOE_RS07795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OEOE_RS07800	COG0601	transmembrane transport
OEOE_RS07805	COG4608	Belongs to the ABC transporter superfamily
OEOE_RS07835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OEOE_RS07850	COG0248	Ppx GppA phosphatase
OEOE_RS07855	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OEOE_RS07860	COG3590	peptidase
OEOE_RS07865	COG0765	amino acid transport
OEOE_RS07870	COG0765	amino acid transport
OEOE_RS07875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OEOE_RS07885	COG1132	(ABC) transporter
OEOE_RS07890	COG1132	(ABC) transporter
OEOE_RS07900	COG0531	amino acid
OEOE_RS07910	COG2337	Toxic component of a toxin-antitoxin (TA) module
OEOE_RS07920	COG0736	holo-[acyl-carrier-protein] synthase activity
OEOE_RS07930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OEOE_RS07935	COG2814	Major facilitator Superfamily
OEOE_RS07940	COG0589	response to stress
OEOE_RS07960	COG0148	phosphopyruvate hydratase activity
OEOE_RS07965	COG3842	ATPase activity
OEOE_RS07990	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OEOE_RS07995	COG0025	NhaP-type Na H and K H
OEOE_RS08005	COG0708	Exodeoxyribonuclease III
OEOE_RS08010	COG3853	Toxic anion resistance protein (TelA)
OEOE_RS08030	COG0802	atpase or kinase
OEOE_RS08035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OEOE_RS08045	COG0765	amino acid transport
OEOE_RS08050	COG1609	Transcriptional regulator
OEOE_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
OEOE_RS08070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OEOE_RS08080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OEOE_RS08085	COG1597	lipid kinase activity
OEOE_RS08100	COG0004	ammonium transporteR
OEOE_RS08105	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OEOE_RS08110	COG2814	Major facilitator Superfamily
OEOE_RS08135	COG0477	Major facilitator Superfamily
OEOE_RS08155	COG1063	alcohol dehydrogenase
OEOE_RS08160	COG0668	transmembrane transport
OEOE_RS08170	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OEOE_RS08175	COG0154	amidase activity
OEOE_RS08180	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OEOE_RS08185	COG3557	Belongs to the UPF0374 family
OEOE_RS08195	COG2137	regulation of response to DNA damage stimulus
OEOE_RS08205	COG0463	Glycosyl transferase, family 2
OEOE_RS08215	COG3118	belongs to the thioredoxin family
OEOE_RS08220	COG0028	Belongs to the TPP enzyme family
OEOE_RS08225	COG3527	Alpha-acetolactate decarboxylase
OEOE_RS08245	COG1940	carbohydrate kinase activity
OEOE_RS08250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OEOE_RS08275	COG4975	Glucose uptake
OEOE_RS08280	COG4716	Myosin-crossreactive antigen
OEOE_RS08285	COG1464	Belongs to the NlpA lipoprotein family
OEOE_RS08290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OEOE_RS08295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OEOE_RS08300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OEOE_RS08320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OEOE_RS08325	COG0066	3-isopropylmalate dehydratase activity
OEOE_RS08330	COG2188	Transcriptional regulator
OEOE_RS08335	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OEOE_RS08340	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OEOE_RS08345	COG0544	peptidyl-prolyl cis-trans isomerase activity
OEOE_RS08355	COG1316	TRANSCRIPTIONal
OEOE_RS08365	COG1388	LysM domain
OEOE_RS08365	COG1705	Flagellar rod assembly protein muramidase FlgJ
OEOE_RS08385	COG0463	Glycosyl transferase, family 2
OEOE_RS08385	COG1216	Glycosyl transferase, family 2
OEOE_RS08400	COG0562	UDP-galactopyranose mutase
OEOE_RS08405	COG1216	Glycosyl transferase, family 2
OEOE_RS08425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OEOE_RS08425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OEOE_RS08430	COG1113	amino acid transport
OEOE_RS08435	COG1418	mRNA catabolic process
OEOE_RS08440	COG0783	Belongs to the Dps family
OEOE_RS08475	COG1045	serine acetyltransferase
OEOE_RS08480	COG0626	cystathionine gamma-synthase activity
OEOE_RS08485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OEOE_RS08505	COG0679	Auxin Efflux Carrier
OEOE_RS08515	COG2814	Major facilitator Superfamily
OEOE_RS08520	COG2249	NAD(P)H dehydrogenase (quinone) activity
OEOE_RS08540	COG2205	protein histidine kinase activity
OEOE_RS08545	COG0745	RESPONSE REGULATOR receiver
OEOE_RS08580	COG1063	alcohol dehydrogenase
OEOE_RS08590	COG4989	oxidoreductase activity
OEOE_RS08600	COG0254	rRNA binding
OEOE_RS08605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OEOE_RS08615	COG3343	RNA polymerase activity
OEOE_RS08625	COG1078	dGTPase activity
OEOE_RS08630	COG0589	response to stress
OEOE_RS08650	COG1914	H( )-stimulated, divalent metal cation uptake system
OEOE_RS08660	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OEOE_RS08665	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
OEOE_RS08685	COG1131	(ABC) transporter
OEOE_RS08690	COG1725	Transcriptional regulator
OEOE_RS08700	COG1131	(ABC) transporter
OEOE_RS08705	COG0765	amino acid transport
OEOE_RS08710	COG0252	asparaginase activity
OEOE_RS08715	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OEOE_RS08740	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
OEOE_RS08745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OEOE_RS08755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OEOE_RS08770	COG0028	Belongs to the TPP enzyme family
OEOE_RS08785	COG1968	undecaprenyl-diphosphatase activity
OEOE_RS08795	COG0583	DNA-binding transcription factor activity
OEOE_RS08820	COG2267	carboxylic ester hydrolase activity
OEOE_RS08860	COG0142	geranyltranstransferase activity
OEOE_RS08865	COG1294	oxidase, subunit
OEOE_RS08870	COG1271	oxidase subunit
OEOE_RS08875	COG1252	NADH dehydrogenase
OEOE_RS08880	COG1388	LysM domain
OEOE_RS08880	COG3942	CHAP domain
OEOE_RS08910	COG0561	phosphatase activity
OEOE_RS08940	COG1764	response to oxidative stress
OEOE_RS08945	COG0477	Major facilitator Superfamily
OEOE_RS08955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OEOE_RS08970	COG0656	L-ascorbic acid biosynthetic process
OEOE_RS08995	COG0594	ribonuclease P activity
OEOE_RS09010	COG1609	Transcriptional regulator
OEOE_RS09025	COG1316	TRANSCRIPTIONal