locus-tag	class	description
FFI11_RS00010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FFI11_RS00020	COG1482	cell wall glycoprotein biosynthetic process
FFI11_RS00025	COG2252	PERMEase
FFI11_RS00030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FFI11_RS00055	COG1278	Cold shock
FFI11_RS00080	COG1061	Type III restriction enzyme res subunit
FFI11_RS00095	COG1842	Phage shock protein A
FFI11_RS00120	COG0745	RESPONSE REGULATOR receiver
FFI11_RS00125	COG2205	protein histidine kinase activity
FFI11_RS00150	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFI11_RS00155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFI11_RS00180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFI11_RS00185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFI11_RS00190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFI11_RS00200	COG3433	isochorismatase activity
FFI11_RS00200	COG1535	isochorismatase
FFI11_RS00205	COG1120	ATPase activity
FFI11_RS00215	COG1021	2,3-dihydroxybenzoate-AMP ligase
FFI11_RS00220	COG1169	isochorismate synthase
FFI11_RS00225	COG1028	Short-chain dehydrogenase reductase Sdr
FFI11_RS00230	COG3433	isochorismatase activity
FFI11_RS00230	COG1535	isochorismatase
FFI11_RS00235	COG0459	protein refolding
FFI11_RS00245	COG1233	COG1233 Phytoene dehydrogenase and related
FFI11_RS00250	COG1278	Cold shock
FFI11_RS00265	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FFI11_RS00310	COG3842	ATPase activity
FFI11_RS00320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFI11_RS00325	COG0215	cysteine-tRNA ligase activity
FFI11_RS00360	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FFI11_RS00365	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FFI11_RS00370	COG1329	Transcriptional regulator
FFI11_RS00380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FFI11_RS00405	COG0745	RESPONSE REGULATOR receiver
FFI11_RS00410	COG5002	protein histidine kinase activity
FFI11_RS00415	COG0704	Plays a role in the regulation of phosphate uptake
FFI11_RS00420	COG0588	phosphoglycerate mutase activity
FFI11_RS00445	COG0297	glycogen (starch) synthase activity
FFI11_RS00465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FFI11_RS00470	COG0157	Belongs to the NadC ModD family
FFI11_RS00475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FFI11_RS00480	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FFI11_RS00485	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FFI11_RS00510	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FFI11_RS00520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FFI11_RS00525	COG0302	gtp cyclohydrolase
FFI11_RS00530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FFI11_RS00540	COG0037	tRNA processing
FFI11_RS00550	COG2027	D-alanyl-D-alanine carboxypeptidase
FFI11_RS00555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FFI11_RS00560	COG0791	NLP P60 protein
FFI11_RS00560	COG3883	PFAM NLP P60 protein
FFI11_RS00565	COG2873	o-acetylhomoserine
FFI11_RS00570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FFI11_RS00580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FFI11_RS00585	COG1920	GTP binding
FFI11_RS00595	COG0778	Nitroreductase
FFI11_RS00600	COG0531	amino acid
FFI11_RS00605	COG0247	lactate metabolic process
FFI11_RS00605	COG0277	FAD linked oxidase domain protein
FFI11_RS00610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FFI11_RS00640	COG0393	Putative heavy-metal-binding
FFI11_RS00655	COG1404	Belongs to the peptidase S8 family
FFI11_RS00670	COG0084	hydrolase, TatD family'
FFI11_RS00685	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FFI11_RS00760	COG1490	D-aminoacyl-tRNA deacylase activity
FFI11_RS00785	COG4129	membrane
FFI11_RS00795	COG3485	protocatechuate 3,4-dioxygenase
FFI11_RS00825	COG2267	carboxylic ester hydrolase activity
FFI11_RS00845	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FFI11_RS00850	COG1408	metallophosphoesterase
FFI11_RS00870	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FFI11_RS00880	COG1802	Transcriptional regulator
FFI11_RS00890	COG2116	formate transmembrane transporter activity
FFI11_RS00925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FFI11_RS00935	COG1131	(ABC) transporter
FFI11_RS00945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FFI11_RS00985	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FFI11_RS00990	COG0346	lactoylglutathione lyase activity
FFI11_RS01000	COG2011	ABC-type metal ion transport system permease component
FFI11_RS01005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FFI11_RS01045	COG1309	transcriptional regulator
FFI11_RS01050	COG1131	(ABC) transporter
FFI11_RS01055	COG3559	Exporter of polyketide antibiotics
FFI11_RS01075	COG2233	PERMEase
FFI11_RS01095	COG1132	(ABC) transporter
FFI11_RS01100	COG1309	transcriptional regulator
FFI11_RS01115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FFI11_RS01125	COG2890	protein-(glutamine-N5) methyltransferase activity
FFI11_RS01185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS01190	COG1309	transcriptional regulator
FFI11_RS01195	COG1960	acyl-CoA dehydrogenase activity
FFI11_RS01200	COG0183	Belongs to the thiolase family
FFI11_RS01250	COG0681	Belongs to the peptidase S26 family
FFI11_RS01255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FFI11_RS01300	COG1609	Transcriptional regulator
FFI11_RS01315	COG0395	ABC-type sugar transport system, permease component
FFI11_RS01320	COG1175	transmembrane transport
FFI11_RS01340	COG0590	tRNA wobble adenosine to inosine editing
FFI11_RS01345	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FFI11_RS01350	COG0745	RESPONSE REGULATOR receiver
FFI11_RS01360	COG0435	Glutathione S-transferase
FFI11_RS01380	COG0789	Transcriptional regulator
FFI11_RS01385	COG0484	heat shock protein binding
FFI11_RS01395	COG0443	Heat shock 70 kDa protein
FFI11_RS01400	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FFI11_RS01420	COG1278	Cold shock
FFI11_RS01430	COG0789	Transcriptional regulator
FFI11_RS01430	COG4978	Transcriptional regulator
FFI11_RS01460	COG0640	Transcriptional regulator
FFI11_RS01470	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FFI11_RS01475	COG0577	efflux transmembrane transporter activity
FFI11_RS01475	COG1136	(ABC) transporter
FFI11_RS01595	COG0166	Belongs to the GPI family
FFI11_RS01625	COG3842	ATPase activity
FFI11_RS01660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFI11_RS01670	COG1609	Transcriptional regulator
FFI11_RS01690	COG0315	cyclic pyranopterin monophosphate synthase activity
FFI11_RS01710	COG0315	cyclic pyranopterin monophosphate synthase activity
FFI11_RS01710	COG0521	Mo-molybdopterin cofactor biosynthetic process
FFI11_RS01735	COG0477	Major facilitator Superfamily
FFI11_RS01745	COG1012	belongs to the aldehyde dehydrogenase family
FFI11_RS01755	COG1309	transcriptional regulator
FFI11_RS01785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFI11_RS01790	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FFI11_RS01835	COG1082	Xylose isomerase domain protein TIM barrel
FFI11_RS01840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFI11_RS01845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFI11_RS01850	COG1263	PTS System
FFI11_RS01855	COG2188	Transcriptional regulator
FFI11_RS01860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFI11_RS01865	COG1263	PTS System
FFI11_RS01865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFI11_RS01870	COG2190	(PTS) system
FFI11_RS01905	COG2378	regulation of single-species biofilm formation
FFI11_RS01915	COG3459	Glycosyltransferase 36 associated
FFI11_RS01920	COG1309	transcriptional regulator
FFI11_RS01930	COG1175	transmembrane transport
FFI11_RS01935	COG0395	ABC-type sugar transport system, permease component
FFI11_RS01940	COG2723	6-phospho-beta-galactosidase activity
FFI11_RS01945	COG1506	peptidase
FFI11_RS01945	COG4946	Tricorn protease homolog
FFI11_RS01945	COG0823	Involved in the tonB-independent uptake of proteins
FFI11_RS01955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFI11_RS01960	COG2188	Transcriptional regulator
FFI11_RS01975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FFI11_RS01980	COG3639	organic phosphonate transmembrane transporter activity
FFI11_RS01995	COG0714	Associated with various cellular activities
FFI11_RS02040	COG3591	Belongs to the peptidase S1B family
FFI11_RS02060	COG4941	Belongs to the sigma-70 factor family
FFI11_RS02065	COG3795	YCII-related domain
FFI11_RS02075	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFI11_RS02080	COG0022	dehydrogenase e1 component
FFI11_RS02095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FFI11_RS02100	COG1950	PFAM Membrane protein of
FFI11_RS02120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FFI11_RS02135	COG1649	PFAM Uncharacterised BCR, COG1649
FFI11_RS02160	COG0248	Ppx GppA phosphatase
FFI11_RS02200	COG0494	nUDIX hydrolase
FFI11_RS02205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FFI11_RS02210	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FFI11_RS02220	COG0181	hydroxymethylbilane synthase activity
FFI11_RS02230	COG0113	porphobilinogen synthase activity
FFI11_RS02235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FFI11_RS02245	COG1937	Protein conserved in bacteria
FFI11_RS02275	COG1131	(ABC) transporter
FFI11_RS02305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFI11_RS02310	COG0601	transmembrane transport
FFI11_RS02330	COG0183	Belongs to the thiolase family
FFI11_RS02355	COG1960	acyl-CoA dehydrogenase activity
FFI11_RS02365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FFI11_RS02370	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFI11_RS02380	COG0022	dehydrogenase e1 component
FFI11_RS02410	COG0254	rRNA binding
FFI11_RS02415	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FFI11_RS02420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FFI11_RS02425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FFI11_RS02435	COG0366	Alpha amylase catalytic
FFI11_RS02435	COG1470	cell adhesion involved in biofilm formation
FFI11_RS02445	COG0395	ABC-type sugar transport system, permease component
FFI11_RS02495	COG1228	amidohydrolase
FFI11_RS02500	COG0531	amino acid
FFI11_RS02505	COG0076	glutamate decarboxylase activity
FFI11_RS02530	COG0604	alcohol dehydrogenase
FFI11_RS02545	COG2197	response regulator
FFI11_RS02555	COG1301	dicarboxylic acid transport
FFI11_RS02575	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FFI11_RS02580	COG0586	Pfam SNARE associated Golgi protein
FFI11_RS02600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FFI11_RS02630	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FFI11_RS02635	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FFI11_RS02650	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FFI11_RS02670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FFI11_RS02675	COG0110	maltose O-acetyltransferase activity
FFI11_RS02680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS02700	COG2197	response regulator
FFI11_RS02705	COG0588	phosphoglycerate mutase activity
FFI11_RS02725	COG0318	PFAM AMP-dependent synthetase and ligase
FFI11_RS02730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FFI11_RS02750	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FFI11_RS02795	COG0628	permease
FFI11_RS02835	COG2197	response regulator
FFI11_RS02845	COG0596	Alpha beta hydrolase
FFI11_RS02850	COG1063	alcohol dehydrogenase
FFI11_RS02855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFI11_RS02865	COG1116	anion transmembrane transporter activity
FFI11_RS02870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFI11_RS02875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFI11_RS02990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FFI11_RS03005	COG0351	phosphomethylpyrimidine kinase
FFI11_RS03010	COG2197	response regulator
FFI11_RS03040	COG0431	NADPH-dependent FMN reductase
FFI11_RS03055	COG1742	UPF0060 membrane protein
FFI11_RS03080	COG2197	response regulator
FFI11_RS03100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFI11_RS03110	COG0789	Transcriptional regulator
FFI11_RS03120	COG0656	L-ascorbic acid biosynthetic process
FFI11_RS03125	COG2814	Major facilitator Superfamily
FFI11_RS03130	COG1846	Transcriptional regulator
FFI11_RS03150	COG1755	Isoprenylcysteine carboxyl methyltransferase
FFI11_RS03155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFI11_RS03170	COG2197	response regulator
FFI11_RS03175	COG4585	Histidine kinase
FFI11_RS03215	COG2130	NADP-dependent
FFI11_RS03225	COG2197	response regulator
FFI11_RS03235	COG2197	response regulator
FFI11_RS03240	COG4585	Histidine kinase
FFI11_RS03260	COG1357	PFAM Pentapeptide repeats (8 copies)
FFI11_RS03275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FFI11_RS03300	COG2211	Major facilitator Superfamily
FFI11_RS03310	COG1940	carbohydrate kinase activity
FFI11_RS03360	COG0596	Alpha beta hydrolase
FFI11_RS03390	COG0659	secondary active sulfate transmembrane transporter activity
FFI11_RS03470	COG1063	alcohol dehydrogenase
FFI11_RS03480	COG2066	Belongs to the glutaminase family
FFI11_RS03515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFI11_RS03520	COG1733	regulation of RNA biosynthetic process
FFI11_RS03530	COG2814	Major facilitator Superfamily
FFI11_RS03590	COG0210	DNA helicase
FFI11_RS03610	COG0305	Participates in initiation and elongation during chromosome replication
FFI11_RS03610	COG1372	Participates in initiation and elongation during chromosome replication
FFI11_RS03615	COG0534	Mate efflux family protein
FFI11_RS03620	COG0359	binds to the 23S rRNA
FFI11_RS03625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FFI11_RS03635	COG0360	Binds together with S18 to 16S ribosomal RNA
FFI11_RS03640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FFI11_RS03650	COG1260	myo-inositol-1-phosphate synthase
FFI11_RS03665	COG2814	Major facilitator Superfamily
FFI11_RS03670	COG0617	tRNA 3'-terminal CCA addition
FFI11_RS03685	COG0728	peptidoglycan biosynthetic process
FFI11_RS03695	COG0492	ferredoxin-NADP+ reductase activity
FFI11_RS03700	COG3118	belongs to the thioredoxin family
FFI11_RS03705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFI11_RS03710	COG1181	Belongs to the D-alanine--D-alanine ligase family
FFI11_RS03720	COG1192	Involved in chromosome partitioning
FFI11_RS03725	COG0357	Ribosomal RNA small subunit methyltransferase G
FFI11_RS03730	COG1847	R3H domain protein
FFI11_RS03735	COG0706	membrane insertase activity
FFI11_RS03740	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FFI11_RS03745	COG0594	ribonuclease P activity
FFI11_RS03750	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FFI11_RS03755	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FFI11_RS03760	COG0592	DNA-directed DNA polymerase activity
FFI11_RS03765	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FFI11_RS03770	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FFI11_RS03775	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FFI11_RS03780	COG0187	DNA topoisomerase II activity
FFI11_RS03785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FFI11_RS03815	COG0705	Rhomboid family
FFI11_RS03830	COG3764	Sortase (surface protein transpeptidase)
FFI11_RS03845	COG0515	serine threonine protein kinase
FFI11_RS03850	COG0768	penicillin binding
FFI11_RS03865	COG1716	ATPase activity
FFI11_RS03895	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FFI11_RS03920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FFI11_RS03935	COG4251	negative regulation of phosphorylation
FFI11_RS03950	COG0436	Aminotransferase
FFI11_RS03980	COG0039	L-malate dehydrogenase activity
FFI11_RS03985	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FFI11_RS03985	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FFI11_RS03990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FFI11_RS03995	COG0509	glycine decarboxylation via glycine cleavage system
FFI11_RS04000	COG2197	response regulator
FFI11_RS04005	COG0494	nUDIX hydrolase
FFI11_RS04010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FFI11_RS04050	COG1216	Glycosyl transferase, family 2
FFI11_RS04070	COG0384	phenazine biosynthesis protein PhzF
FFI11_RS04075	COG0346	lactoylglutathione lyase activity
FFI11_RS04130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFI11_RS04140	COG1937	Protein conserved in bacteria
FFI11_RS04170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FFI11_RS04180	COG1501	Belongs to the glycosyl hydrolase 31 family
FFI11_RS04185	COG3387	PFAM Glycoside hydrolase 15-related
FFI11_RS04195	COG0395	ABC-type sugar transport system, permease component
FFI11_RS04200	COG1175	transmembrane transport
FFI11_RS04205	COG1846	Transcriptional regulator
FFI11_RS04205	COG1940	carbohydrate kinase activity
FFI11_RS04220	COG0204	Acyl-transferase
FFI11_RS04220	COG0318	PFAM AMP-dependent synthetase and ligase
FFI11_RS04255	COG2197	response regulator
FFI11_RS04260	COG3851	Histidine kinase
FFI11_RS04265	COG1760	l-serine dehydratase
FFI11_RS04270	COG0519	Catalyzes the synthesis of GMP from XMP
FFI11_RS04290	COG2855	membrane
FFI11_RS04310	COG1643	Atp-dependent helicase
FFI11_RS04355	COG2337	Toxic component of a toxin-antitoxin (TA) module
FFI11_RS04385	COG1876	peptidase activity
FFI11_RS04400	COG0488	(ABC) transporter
FFI11_RS04415	COG0442	prolyl-tRNA aminoacylation
FFI11_RS04425	COG0420	3'-5' exonuclease activity
FFI11_RS04430	COG0419	ATPase involved in DNA repair
FFI11_RS04445	COG2814	Major facilitator Superfamily
FFI11_RS04450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS04480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFI11_RS04485	COG0765	amino acid transport
FFI11_RS04490	COG1126	abc transporter atp-binding protein
FFI11_RS04510	COG1136	(ABC) transporter
FFI11_RS04545	COG1278	Cold shock
FFI11_RS04550	COG0726	polysaccharide deacetylase
FFI11_RS04585	COG1472	Belongs to the glycosyl hydrolase 3 family
FFI11_RS04605	COG0402	S-adenosylhomocysteine deaminase activity
FFI11_RS04625	COG2207	Transcriptional regulator
FFI11_RS04645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FFI11_RS04660	COG1609	Transcriptional regulator
FFI11_RS04665	COG1653	transport
FFI11_RS04670	COG1175	transmembrane transport
FFI11_RS04680	COG1472	Belongs to the glycosyl hydrolase 3 family
FFI11_RS04780	COG3012	SEC-C Motif Domain Protein
FFI11_RS04860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFI11_RS04870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FFI11_RS04875	COG2301	Belongs to the HpcH HpaI aldolase family
FFI11_RS04920	COG1199	ATP-dependent helicase activity
FFI11_RS04920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FFI11_RS04945	COG0071	Belongs to the small heat shock protein (HSP20) family
FFI11_RS04955	COG0702	epimerase
FFI11_RS04960	COG1764	response to oxidative stress
FFI11_RS04965	COG1113	amino acid transport
FFI11_RS04970	COG4585	Histidine kinase
FFI11_RS04975	COG2197	response regulator
FFI11_RS04980	COG0671	phosphoesterase, PA-phosphatase related
FFI11_RS04990	COG1131	(ABC) transporter
FFI11_RS04995	COG2409	Drug exporters of the RND superfamily
FFI11_RS05010	COG1129	ABC transporter
FFI11_RS05015	COG1511	domain protein
FFI11_RS05020	COG1309	transcriptional regulator
FFI11_RS05025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FFI11_RS05030	COG2234	aminopeptidase activity
FFI11_RS05035	COG0531	amino acid
FFI11_RS05040	COG2258	MOSC domain
FFI11_RS05050	COG0588	phosphoglycerate mutase activity
FFI11_RS05065	COG1940	carbohydrate kinase activity
FFI11_RS05070	COG0446	pyridine nucleotide-disulphide oxidoreductase
FFI11_RS05085	COG1937	Protein conserved in bacteria
FFI11_RS05105	COG1120	ATPase activity
FFI11_RS05110	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFI11_RS05115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFI11_RS05135	COG0328	RNA-DNA hybrid ribonuclease activity
FFI11_RS05140	COG0545	Peptidyl-prolyl cis-trans isomerase
FFI11_RS05155	COG3265	gluconokinase activity
FFI11_RS05165	COG0477	Major facilitator Superfamily
FFI11_RS05185	COG0477	Major facilitator Superfamily
FFI11_RS05190	COG2197	response regulator
FFI11_RS05240	COG0028	Belongs to the TPP enzyme family
FFI11_RS05265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFI11_RS05285	COG1857	crispr-associated protein
FFI11_RS05300	COG1518	maintenance of DNA repeat elements
FFI11_RS05325	COG0463	Glycosyl transferase, family 2
FFI11_RS05335	COG0628	permease
FFI11_RS05340	COG1597	lipid kinase activity
FFI11_RS05350	COG1132	(ABC) transporter
FFI11_RS05375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFI11_RS05380	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFI11_RS05385	COG1120	ATPase activity
FFI11_RS05390	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FFI11_RS05405	COG1609	Transcriptional regulator
FFI11_RS05410	COG1653	transport
FFI11_RS05415	COG1175	transmembrane transport
FFI11_RS05420	COG0395	ABC-type sugar transport system, permease component
FFI11_RS05435	COG1063	alcohol dehydrogenase
FFI11_RS05445	COG2018	Roadblock/LC7 domain
FFI11_RS05475	COG2409	Drug exporters of the RND superfamily
FFI11_RS05490	COG1136	(ABC) transporter
FFI11_RS05505	COG0179	Fumarylacetoacetate (FAA) hydrolase
FFI11_RS05510	COG3158	transport of potassium into the cell
FFI11_RS05565	COG1609	Transcriptional regulator
FFI11_RS05575	COG1175	transmembrane transport
FFI11_RS05580	COG0395	ABC-type sugar transport system, permease component
FFI11_RS05600	COG3585	molybdate ion transport
FFI11_RS05620	COG0717	Belongs to the dCTP deaminase family
FFI11_RS05635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FFI11_RS05635	COG2111	Na H antiporter
FFI11_RS05640	COG1006	Multisubunit Na H antiporter MnhC subunit
FFI11_RS05645	COG0651	ATP synthesis coupled electron transport
FFI11_RS05660	COG1320	monovalent cation:proton antiporter activity
FFI11_RS05680	COG2267	carboxylic ester hydrolase activity
FFI11_RS05695	COG2340	Cysteine-rich secretory protein family
FFI11_RS05700	COG1597	lipid kinase activity
FFI11_RS05705	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FFI11_RS05710	COG2197	response regulator
FFI11_RS05715	COG4585	Histidine kinase
FFI11_RS05725	COG1131	(ABC) transporter
FFI11_RS05735	COG1472	Belongs to the glycosyl hydrolase 3 family
FFI11_RS05750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FFI11_RS05765	COG4221	oxidoreductase activity
FFI11_RS05775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FFI11_RS05785	COG1704	LemA family
FFI11_RS05795	COG4565	transcriptional regulatory protein
FFI11_RS05800	COG3290	protein histidine kinase activity
FFI11_RS05805	COG3181	Tripartite tricarboxylate transporter family receptor
FFI11_RS05820	COG0589	response to stress
FFI11_RS05840	COG0191	fructose-bisphosphate aldolase activity
FFI11_RS05865	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FFI11_RS05890	COG0151	Belongs to the GarS family
FFI11_RS05895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FFI11_RS05910	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FFI11_RS05915	COG0047	phosphoribosylformylglycinamidine synthase activity
FFI11_RS05935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS05945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFI11_RS05955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FFI11_RS05965	COG3237	CsbD-like
FFI11_RS05975	COG3104	oligopeptide transport
FFI11_RS05985	COG2030	dehydratase
FFI11_RS06020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FFI11_RS06050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS06055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFI11_RS06075	COG1793	dna ligase
FFI11_RS06085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS06090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS06105	COG0765	amino acid transport
FFI11_RS06110	COG1126	abc transporter atp-binding protein
FFI11_RS06115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFI11_RS06125	COG0778	Nitroreductase
FFI11_RS06130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS06140	COG0456	acetyltransferase
FFI11_RS06145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS06150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS06160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FFI11_RS06170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FFI11_RS06185	COG0601	transmembrane transport
FFI11_RS06190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFI11_RS06200	COG4608	Belongs to the ABC transporter superfamily
FFI11_RS06205	COG0557	exoribonuclease II activity
FFI11_RS06215	COG0737	Belongs to the 5'-nucleotidase family
FFI11_RS06230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FFI11_RS06275	COG0640	Transcriptional regulator
FFI11_RS06285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FFI11_RS06390	COG0584	glycerophosphoryl diester phosphodiesterase
FFI11_RS06395	COG1653	transport
FFI11_RS06400	COG0395	ABC-type sugar transport system, permease component
FFI11_RS06405	COG1175	transmembrane transport
FFI11_RS06455	COG0745	RESPONSE REGULATOR receiver
FFI11_RS06460	COG2205	protein histidine kinase activity
FFI11_RS06485	COG2226	methyltransferase
FFI11_RS06530	COG0577	efflux transmembrane transporter activity
FFI11_RS06530	COG1136	(ABC) transporter
FFI11_RS06555	COG0513	Belongs to the DEAD box helicase family
FFI11_RS06560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFI11_RS06575	COG0477	Major facilitator Superfamily
FFI11_RS06595	COG0306	phosphate transporter
FFI11_RS06610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FFI11_RS06615	COG0456	acetyltransferase
FFI11_RS06625	COG2072	flavoprotein involved in K transport
FFI11_RS06630	COG0477	Major facilitator Superfamily
FFI11_RS06635	COG0514	ATP-dependent DNA helicase (RecQ)
FFI11_RS06650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFI11_RS06665	COG0492	ferredoxin-NADP+ reductase activity
FFI11_RS06690	COG4941	Belongs to the sigma-70 factor family
FFI11_RS06705	COG2267	carboxylic ester hydrolase activity
FFI11_RS06735	COG1205	dead DEAH box helicase
FFI11_RS06735	COG1111	helicase
FFI11_RS06740	COG1362	aminopeptidase activity
FFI11_RS06745	COG2890	protein-(glutamine-N5) methyltransferase activity
FFI11_RS06760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FFI11_RS06780	COG1876	peptidase activity
FFI11_RS06790	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FFI11_RS06790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FFI11_RS06795	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FFI11_RS06815	COG2890	protein-(glutamine-N5) methyltransferase activity
FFI11_RS06835	COG0583	DNA-binding transcription factor activity
FFI11_RS06855	COG4942	peptidase
FFI11_RS06875	COG0745	RESPONSE REGULATOR receiver
FFI11_RS06890	COG4166	transmembrane transport
FFI11_RS06895	COG4608	Belongs to the ABC transporter superfamily
FFI11_RS06900	COG0601	transmembrane transport
FFI11_RS06905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFI11_RS06910	COG0444	Belongs to the ABC transporter superfamily
FFI11_RS06920	COG1754	DNA topoisomerase type I activity
FFI11_RS06920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FFI11_RS06930	COG1136	(ABC) transporter
FFI11_RS06930	COG0577	efflux transmembrane transporter activity
FFI11_RS06935	COG0577	efflux transmembrane transporter activity
FFI11_RS06935	COG1136	(ABC) transporter
FFI11_RS06945	COG0673	inositol 2-dehydrogenase activity
FFI11_RS06950	COG0673	inositol 2-dehydrogenase activity
FFI11_RS06960	COG1846	Transcriptional regulator
FFI11_RS06980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFI11_RS06985	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FFI11_RS07030	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FFI11_RS07045	COG1309	transcriptional regulator
FFI11_RS07110	COG1733	regulation of RNA biosynthetic process
FFI11_RS07125	COG0406	alpha-ribazole phosphatase activity
FFI11_RS07130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FFI11_RS07155	COG1280	lysine exporter protein (LysE YggA)
FFI11_RS07165	COG2814	Major facilitator Superfamily
FFI11_RS07170	COG0583	DNA-binding transcription factor activity
FFI11_RS07200	COG0242	peptide deformylase activity
FFI11_RS07230	COG2217	Heavy metal translocating P-type atpase
FFI11_RS07250	COG2188	Transcriptional regulator
FFI11_RS07255	COG4821	SIS domain
FFI11_RS07270	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FFI11_RS07275	COG1234	tRNA 3'-trailer cleavage
FFI11_RS07310	COG0542	response to heat
FFI11_RS07360	COG3226	Transcriptional regulator
FFI11_RS07365	COG1556	Lactate utilization protein
FFI11_RS07370	COG1139	Iron-sulfur cluster binding protein
FFI11_RS07375	COG0247	lactate metabolic process
FFI11_RS07380	COG2186	Transcriptional regulator
FFI11_RS07405	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FFI11_RS07430	COG2272	Belongs to the type-B carboxylesterase lipase family
FFI11_RS07440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FFI11_RS07460	COG0667	Aldo Keto reductase
FFI11_RS07465	COG4608	Belongs to the ABC transporter superfamily
FFI11_RS07475	COG2115	Belongs to the xylose isomerase family
FFI11_RS07480	COG1070	Carbohydrate kinase
FFI11_RS07520	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FFI11_RS07540	COG0395	ABC-type sugar transport system, permease component
FFI11_RS07545	COG1175	transmembrane transport
FFI11_RS07555	COG0673	inositol 2-dehydrogenase activity
FFI11_RS07575	COG1011	Hydrolase
FFI11_RS07580	COG1802	Transcriptional regulator
FFI11_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
FFI11_RS07605	COG1595	DNA-templated transcription, initiation
FFI11_RS07640	COG1028	Short-chain dehydrogenase reductase Sdr
FFI11_RS07645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFI11_RS07650	COG0179	Fumarylacetoacetate (FAA) hydrolase
FFI11_RS07655	COG3386	PFAM SMP-30 Gluconolaconase
FFI11_RS07660	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FFI11_RS07690	COG0784	Response regulator, receiver
FFI11_RS07690	COG2198	Histidine kinase
FFI11_RS07690	COG0643	Histidine kinase
FFI11_RS07720	COG2201	protein-glutamate methylesterase activity
FFI11_RS07730	COG0745	RESPONSE REGULATOR receiver
FFI11_RS07740	COG0745	RESPONSE REGULATOR receiver
FFI11_RS07755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFI11_RS07760	COG1256	bacterial-type flagellum assembly
FFI11_RS07760	COG4786	Flagellar basal body rod
FFI11_RS07770	COG1191	sigma factor activity
FFI11_RS07775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFI11_RS07780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFI11_RS07785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFI11_RS07805	COG1815	bacterial-type flagellum-dependent cell motility
FFI11_RS07815	COG1677	Flagellar hook-basal body complex protein FliE
FFI11_RS07820	COG1766	The M ring may be actively involved in energy transduction
FFI11_RS07835	COG1157	protein secretion by the type III secretion system
FFI11_RS07895	COG1338	Plays a role in the flagellum-specific transport system
FFI11_RS07910	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFI11_RS07915	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFI11_RS07925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FFI11_RS07955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFI11_RS07960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FFI11_RS07965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FFI11_RS07975	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FFI11_RS07990	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FFI11_RS08000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FFI11_RS08010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FFI11_RS08025	COG0842	Transport permease protein
FFI11_RS08035	COG0569	domain protein
FFI11_RS08040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FFI11_RS08045	COG0123	including yeast histone deacetylase and acetoin utilization protein
FFI11_RS08065	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FFI11_RS08070	COG2353	YceI-like domain
FFI11_RS08080	COG0406	alpha-ribazole phosphatase activity
FFI11_RS08090	COG0785	Cytochrome C biogenesis protein
FFI11_RS08095	COG1333	cytochrome c biogenesis protein
FFI11_RS08100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFI11_RS08120	COG1575	Belongs to the MenA family. Type 1 subfamily
FFI11_RS08130	COG1470	cell adhesion involved in biofilm formation
FFI11_RS08140	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FFI11_RS08150	COG4948	Mandelate Racemase Muconate Lactonizing
FFI11_RS08155	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FFI11_RS08160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFI11_RS08170	COG1169	isochorismate synthase
FFI11_RS08175	COG2226	methyltransferase
FFI11_RS08190	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFI11_RS08195	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFI11_RS08200	COG0649	NAD binding
FFI11_RS08210	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FFI11_RS08215	COG1034	ATP synthesis coupled electron transport
FFI11_RS08220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FFI11_RS08225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFI11_RS08230	COG0839	Belongs to the complex I subunit 6 family
FFI11_RS08235	COG0713	ATP synthesis coupled electron transport
FFI11_RS08240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FFI11_RS08250	COG1007	ATP synthesis coupled electron transport
FFI11_RS08255	COG0142	geranyltranstransferase activity
FFI11_RS08265	COG0714	Associated with various cellular activities
FFI11_RS08285	COG0631	protein serine/threonine phosphatase activity
FFI11_RS08350	COG0501	Belongs to the peptidase M48B family
FFI11_RS08360	COG0561	phosphatase activity
FFI11_RS08365	COG1666	GTP binding
FFI11_RS08390	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FFI11_RS08395	COG2030	dehydratase
FFI11_RS08405	COG1609	Transcriptional regulator
FFI11_RS08410	COG0738	Major facilitator superfamily
FFI11_RS08415	COG0738	Major facilitator superfamily
FFI11_RS08420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FFI11_RS08450	COG0745	RESPONSE REGULATOR receiver
FFI11_RS08455	COG5002	protein histidine kinase activity
FFI11_RS08465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FFI11_RS08470	COG2197	response regulator
FFI11_RS08475	COG4585	Histidine kinase
FFI11_RS08485	COG1131	(ABC) transporter
FFI11_RS08495	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFI11_RS08500	COG0250	Participates in transcription elongation, termination and antitermination
FFI11_RS08505	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FFI11_RS08510	COG0081	regulation of translation
FFI11_RS08545	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FFI11_RS08550	COG0222	ribosome binding
FFI11_RS08555	COG0085	RNA polymerase activity
FFI11_RS08560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FFI11_RS08565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FFI11_RS08570	COG0049	tRNA binding
FFI11_RS08575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FFI11_RS08580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FFI11_RS08585	COG0051	transcription antitermination factor activity, RNA binding
FFI11_RS08590	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FFI11_RS08595	COG0088	Forms part of the polypeptide exit tunnel
FFI11_RS08600	COG0089	rRNA binding
FFI11_RS08605	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FFI11_RS08610	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FFI11_RS08615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FFI11_RS08620	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FFI11_RS08625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FFI11_RS08630	COG0255	Belongs to the universal ribosomal protein uL29 family
FFI11_RS08635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FFI11_RS08640	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FFI11_RS08645	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FFI11_RS08650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FFI11_RS08655	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FFI11_RS08660	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FFI11_RS08665	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FFI11_RS08670	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FFI11_RS08675	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FFI11_RS08685	COG0200	Binds to the 23S rRNA
FFI11_RS08695	COG0563	adenylate kinase activity
FFI11_RS08705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FFI11_RS08710	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FFI11_RS08715	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FFI11_RS08720	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FFI11_RS08725	COG0202	RNA polymerase activity
FFI11_RS08730	COG0203	ribosomal protein L17
FFI11_RS08740	COG1940	carbohydrate kinase activity
FFI11_RS08745	COG0101	tRNA pseudouridine synthase activity
FFI11_RS08760	COG1054	Belongs to the UPF0176 family
FFI11_RS08765	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FFI11_RS08770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FFI11_RS08780	COG0242	peptide deformylase activity
FFI11_RS08790	COG1072	(Pantothenic acid kinase))
FFI11_RS08795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FFI11_RS08800	COG0736	holo-[acyl-carrier-protein] synthase activity
FFI11_RS08805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS08820	COG0564	pseudouridine synthase activity
FFI11_RS08825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFI11_RS08830	COG0802	atpase or kinase
FFI11_RS08850	COG0778	Nitroreductase
FFI11_RS08855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FFI11_RS08865	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FFI11_RS08875	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FFI11_RS08895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FFI11_RS08905	COG0516	GMP reductase activity
FFI11_RS08910	COG0456	acetyltransferase
FFI11_RS08925	COG1012	belongs to the aldehyde dehydrogenase family
FFI11_RS08930	COG2949	membrane
FFI11_RS08940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FFI11_RS08950	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FFI11_RS08965	COG1132	(ABC) transporter
FFI11_RS08970	COG1132	(ABC) transporter
FFI11_RS08985	COG2022	thiamine diphosphate biosynthetic process
FFI11_RS08995	COG2022	thiamine diphosphate biosynthetic process
FFI11_RS08995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFI11_RS09000	COG0352	thiamine-phosphate diphosphorylase activity
FFI11_RS09005	COG0519	Catalyzes the synthesis of GMP from XMP
FFI11_RS09005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FFI11_RS09015	COG0438	transferase activity, transferring glycosyl groups
FFI11_RS09040	COG2197	response regulator
FFI11_RS09050	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FFI11_RS09050	COG1648	precorrin-2 dehydrogenase activity
FFI11_RS09055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFI11_RS09060	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FFI11_RS09080	COG0175	sulfate reduction
FFI11_RS09085	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFI11_RS09120	COG0045	succinate-CoA ligase (ADP-forming) activity
FFI11_RS09150	COG0640	Transcriptional regulator
FFI11_RS09160	COG0138	bifunctional purine biosynthesis protein purh
FFI11_RS09185	COG0039	L-malate dehydrogenase activity
FFI11_RS09200	COG0667	Aldo Keto reductase
FFI11_RS09225	COG0395	ABC-type sugar transport system, permease component
FFI11_RS09240	COG4124	Belongs to the glycosyl hydrolase 26 family
FFI11_RS09260	COG1940	carbohydrate kinase activity
FFI11_RS09260	COG1846	Transcriptional regulator
FFI11_RS09265	COG4213	ABC transporter substrate-binding protein
FFI11_RS09275	COG4214	carbohydrate transport
FFI11_RS09280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FFI11_RS09285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FFI11_RS09315	COG2409	Drug exporters of the RND superfamily
FFI11_RS09325	COG1349	DNA-binding transcription factor activity
FFI11_RS09330	COG0577	efflux transmembrane transporter activity
FFI11_RS09335	COG1136	(ABC) transporter
FFI11_RS09360	COG1136	(ABC) transporter
FFI11_RS09360	COG0577	efflux transmembrane transporter activity
FFI11_RS09385	COG2239	Acts as a magnesium transporter
FFI11_RS09390	COG1349	DNA-binding transcription factor activity
FFI11_RS09395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FFI11_RS09410	COG0191	fructose-bisphosphate aldolase activity
FFI11_RS09440	COG0006	proline dipeptidase activity
FFI11_RS09450	COG0667	Aldo Keto reductase
FFI11_RS09455	COG0613	PHP domain protein
FFI11_RS09460	COG2095	MarC family integral membrane protein
FFI11_RS09505	COG0513	Belongs to the DEAD box helicase family
FFI11_RS09570	COG0210	DNA helicase
FFI11_RS09600	COG3480	Lon protease (S16) C-terminal proteolytic domain
FFI11_RS09610	COG1615	UPF0182 protein
FFI11_RS09640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFI11_RS09645	COG0765	amino acid transport
FFI11_RS09670	COG1254	Belongs to the acylphosphatase family
FFI11_RS09675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FFI11_RS09675	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FFI11_RS09680	COG0477	Major facilitator Superfamily
FFI11_RS09685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FFI11_RS09695	COG0314	molybdopterin synthase activity
FFI11_RS09705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FFI11_RS09710	COG1733	regulation of RNA biosynthetic process
FFI11_RS09715	COG0702	epimerase
FFI11_RS09720	COG2514	catechol 2,3-dioxygenase activity
FFI11_RS09730	COG0589	response to stress
FFI11_RS09735	COG1414	Transcriptional regulator
FFI11_RS09745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFI11_RS09760	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FFI11_RS09770	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FFI11_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
FFI11_RS09810	COG1733	regulation of RNA biosynthetic process
FFI11_RS09840	COG1609	Transcriptional regulator
FFI11_RS09865	COG1115	amino acid carrier protein
FFI11_RS09905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FFI11_RS09910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FFI11_RS09920	COG0667	Aldo Keto reductase
FFI11_RS09935	COG0179	Fumarylacetoacetate (FAA) hydrolase
FFI11_RS09940	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FFI11_RS09940	COG2066	Belongs to the glutaminase family
FFI11_RS09945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFI11_RS09960	COG2855	membrane
FFI11_RS09990	COG2070	2-Nitropropane dioxygenase
FFI11_RS10000	COG1414	Transcriptional regulator
FFI11_RS10005	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FFI11_RS10010	COG0066	3-isopropylmalate dehydratase activity
FFI11_RS10015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS10020	COG2354	Protein conserved in bacteria
FFI11_RS10045	COG1472	Belongs to the glycosyl hydrolase 3 family
FFI11_RS10065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FFI11_RS10070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FFI11_RS10080	COG1131	(ABC) transporter
FFI11_RS10090	COG4585	Histidine kinase
FFI11_RS10095	COG2197	response regulator
FFI11_RS10105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FFI11_RS10130	COG1181	Belongs to the D-alanine--D-alanine ligase family
FFI11_RS10140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FFI11_RS10155	COG1396	sequence-specific DNA binding
FFI11_RS10160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FFI11_RS10165	COG1461	Dihydroxyacetone kinase
FFI11_RS10185	COG0742	ribosomal rna small subunit methyltransferase
FFI11_RS10210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FFI11_RS10215	COG0571	ribonuclease III activity
FFI11_RS10220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FFI11_RS10235	COG0531	amino acid
FFI11_RS10255	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FFI11_RS10260	COG4988	ABC transporter
FFI11_RS10265	COG1294	oxidase, subunit
FFI11_RS10270	COG1271	oxidase subunit
FFI11_RS10275	COG1530	ribonuclease E activity
FFI11_RS10285	COG1435	thymidine kinase activity
FFI11_RS10290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FFI11_RS10325	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FFI11_RS10330	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FFI11_RS10340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFI11_RS10360	COG1174	glycine betaine transport
FFI11_RS10365	COG1174	glycine betaine transport
FFI11_RS10370	COG1125	glycine betaine transport
FFI11_RS10370	COG0517	IMP dehydrogenase activity
FFI11_RS10390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FFI11_RS10410	COG0693	protein deglycase activity
FFI11_RS10415	COG0671	phosphoesterase, PA-phosphatase related
FFI11_RS10455	COG1122	ATPase activity
FFI11_RS10460	COG0183	Belongs to the thiolase family
FFI11_RS10465	COG0318	PFAM AMP-dependent synthetase and ligase
FFI11_RS10470	COG1268	BioY protein
FFI11_RS10530	COG1716	ATPase activity
FFI11_RS10555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFI11_RS10600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FFI11_RS10620	COG1160	GTP binding
FFI11_RS10625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FFI11_RS10640	COG0702	epimerase
FFI11_RS10650	COG1946	Acyl-CoA thioesterase
FFI11_RS10660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFI11_RS10665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFI11_RS10670	COG2190	(PTS) system
FFI11_RS10675	COG0668	transmembrane transport
FFI11_RS10690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FFI11_RS10715	COG0644	oxidoreductase
FFI11_RS10725	COG2086	electron transfer activity
FFI11_RS10730	COG2271	Major facilitator Superfamily
FFI11_RS10735	COG2030	dehydratase
FFI11_RS10765	COG3590	peptidase
FFI11_RS10780	COG4552	Acetyltransferase involved in intracellular survival and related
FFI11_RS10790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS10805	COG1045	serine acetyltransferase
FFI11_RS10845	COG2755	lipolytic protein G-D-S-L family
FFI11_RS10845	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FFI11_RS10850	COG0544	peptidyl-prolyl cis-trans isomerase activity
FFI11_RS10865	COG0740	serine-type endopeptidase activity
FFI11_RS10870	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FFI11_RS10875	COG1022	Amp-dependent synthetase and ligase
FFI11_RS10880	COG1605	Chorismate mutase
FFI11_RS10880	COG0287	Prephenate dehydrogenase
FFI11_RS10900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS10905	COG0778	Nitroreductase
FFI11_RS10905	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FFI11_RS10960	COG1832	CoA-binding protein
FFI11_RS10965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FFI11_RS10970	COG4139	cobalamin transport
FFI11_RS11020	COG1472	Belongs to the glycosyl hydrolase 3 family
FFI11_RS11025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FFI11_RS11030	COG0285	dihydrofolate synthase activity
FFI11_RS11035	COG2376	Dihydroxyacetone kinase
FFI11_RS11040	COG1461	Dihydroxyacetone kinase
FFI11_RS11055	COG0477	Major facilitator Superfamily
FFI11_RS11065	COG0105	UTP biosynthetic process
FFI11_RS11095	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FFI11_RS11110	COG0228	four-way junction DNA binding
FFI11_RS11115	COG1837	Belongs to the UPF0109 family
FFI11_RS11120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FFI11_RS11125	COG0336	Belongs to the RNA methyltransferase TrmD family
FFI11_RS11130	COG0335	large ribosomal subunit rRNA binding
FFI11_RS11135	COG0681	Belongs to the peptidase S26 family
FFI11_RS11140	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FFI11_RS11150	COG0792	nuclease activity
FFI11_RS11170	COG4974	Belongs to the 'phage' integrase family
FFI11_RS11180	COG0052	Belongs to the universal ribosomal protein uS2 family
FFI11_RS11185	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FFI11_RS11195	COG0233	cytoplasmic translational termination
FFI11_RS11200	COG0575	Belongs to the CDS family
FFI11_RS11205	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FFI11_RS11215	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FFI11_RS11220	COG0750	zinc metalloprotease
FFI11_RS11225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FFI11_RS11235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FFI11_RS11240	COG0442	prolyl-tRNA aminoacylation
FFI11_RS11250	COG0779	Required for maturation of 30S ribosomal subunits
FFI11_RS11265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FFI11_RS11270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FFI11_RS11275	COG0477	Major facilitator Superfamily
FFI11_RS11285	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FFI11_RS11295	COG1131	(ABC) transporter
FFI11_RS11310	COG0577	efflux transmembrane transporter activity
FFI11_RS11310	COG1136	(ABC) transporter
FFI11_RS11320	COG4585	Histidine kinase
FFI11_RS11325	COG2197	response regulator
FFI11_RS11330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FFI11_RS11335	COG1185	polyribonucleotide nucleotidyltransferase activity
FFI11_RS11340	COG0612	Peptidase, M16
FFI11_RS11345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FFI11_RS11380	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FFI11_RS11405	COG1674	ftsk spoiiie
FFI11_RS11420	COG1546	Belongs to the CinA family
FFI11_RS11420	COG1058	Belongs to the CinA family
FFI11_RS11425	COG1396	sequence-specific DNA binding
FFI11_RS11430	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FFI11_RS11435	COG1201	RNA secondary structure unwinding
FFI11_RS11455	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FFI11_RS11460	COG2137	regulation of response to DNA damage stimulus
FFI11_RS11465	COG0765	amino acid transport
FFI11_RS11470	COG0765	amino acid transport
FFI11_RS11475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFI11_RS11480	COG1126	abc transporter atp-binding protein
FFI11_RS11485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFI11_RS11515	COG0326	Molecular chaperone. Has ATPase activity
FFI11_RS11530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FFI11_RS11535	COG2813	Specifically methylates the guanine in position
FFI11_RS11540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FFI11_RS11555	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FFI11_RS11565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FFI11_RS11570	COG0667	Aldo Keto reductase
FFI11_RS11580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFI11_RS11595	COG4251	negative regulation of phosphorylation
FFI11_RS11600	COG0784	Response regulator, receiver
FFI11_RS11610	COG1278	Cold shock
FFI11_RS11625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FFI11_RS11645	COG0714	Associated with various cellular activities
FFI11_RS11650	COG2001	Belongs to the MraZ family
FFI11_RS11655	COG0275	rRNA processing
FFI11_RS11665	COG0768	penicillin binding
FFI11_RS11670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FFI11_RS11680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFI11_RS11685	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FFI11_RS11695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FFI11_RS11700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FFI11_RS11705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FFI11_RS11710	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FFI11_RS11720	COG1799	cell septum assembly
FFI11_RS11740	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FFI11_RS11750	COG2153	protein acetylation
FFI11_RS11755	COG0587	DNA-directed DNA polymerase activity
FFI11_RS11770	COG2501	S4 domain
FFI11_RS11775	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FFI11_RS11805	COG0131	Imidazoleglycerol-phosphate dehydratase
FFI11_RS11815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FFI11_RS11820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FFI11_RS11835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFI11_RS11860	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FFI11_RS11865	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FFI11_RS11870	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FFI11_RS11875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFI11_RS11885	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FFI11_RS11895	COG0300	oxidoreductase activity
FFI11_RS11915	COG2267	carboxylic ester hydrolase activity
FFI11_RS11925	COG0351	phosphomethylpyrimidine kinase
FFI11_RS11925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FFI11_RS11925	COG0352	thiamine-phosphate diphosphorylase activity
FFI11_RS11935	COG0604	alcohol dehydrogenase
FFI11_RS11950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FFI11_RS11965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FFI11_RS11980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FFI11_RS11990	COG1438	arginine binding
FFI11_RS11995	COG0137	argininosuccinate synthase activity
FFI11_RS12000	COG0165	Argininosuccinate lyase
FFI11_RS12005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FFI11_RS12010	COG2094	Belongs to the DNA glycosylase MPG family
FFI11_RS12015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FFI11_RS12055	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FFI11_RS12060	COG0497	DNA recombination
FFI11_RS12085	COG0504	CTP synthase activity
FFI11_RS12090	COG0494	nUDIX hydrolase
FFI11_RS12105	COG0110	maltose O-acetyltransferase activity
FFI11_RS12125	COG1612	heme a metabolic process
FFI11_RS12140	COG1131	(ABC) transporter
FFI11_RS12155	COG0719	Fe-S assembly protein
FFI11_RS12165	COG0396	ATPase activity
FFI11_RS12180	COG2151	metal-sulfur cluster biosynthetic enzyme
FFI11_RS12205	COG0488	(ABC) transporter
FFI11_RS12225	COG1028	Short-chain dehydrogenase reductase Sdr
FFI11_RS12235	COG2062	phosphohistidine phosphatase, SixA
FFI11_RS12240	COG0560	Phosphoserine phosphatase
FFI11_RS12250	COG0297	glycogen (starch) synthase activity
FFI11_RS12260	COG1119	ATPase activity
FFI11_RS12315	COG1140	nitrate reductase beta subunit
FFI11_RS12320	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FFI11_RS12330	COG0314	molybdopterin synthase activity
FFI11_RS12335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FFI11_RS12370	COG1966	Carbon starvation protein
FFI11_RS12380	COG3275	phosphorelay sensor kinase activity
FFI11_RS12385	COG3279	Response regulator of the LytR AlgR family
FFI11_RS12395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFI11_RS12400	COG0017	Asparaginyl-tRNA synthetase
FFI11_RS12405	COG1136	(ABC) transporter
FFI11_RS12420	COG1120	ATPase activity
FFI11_RS12445	COG1881	PFAM PEBP family protein
FFI11_RS12450	COG3550	peptidyl-serine autophosphorylation
FFI11_RS12475	COG0587	DNA-directed DNA polymerase activity
FFI11_RS12485	COG0454	-acetyltransferase
FFI11_RS12520	COG0673	inositol 2-dehydrogenase activity
FFI11_RS12535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FFI11_RS12545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FFI11_RS12565	COG1876	peptidase activity
FFI11_RS12590	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FFI11_RS12595	COG1690	Belongs to the RtcB family
FFI11_RS12600	COG0686	Belongs to the AlaDH PNT family
FFI11_RS12605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFI11_RS12610	COG0339	signal peptide processing
FFI11_RS12620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFI11_RS12630	COG0667	Aldo Keto reductase
FFI11_RS12640	COG0598	Magnesium transport protein CorA
FFI11_RS12645	COG0215	cysteine-tRNA ligase activity
FFI11_RS12660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFI11_RS12675	COG0517	IMP dehydrogenase activity
FFI11_RS12675	COG1994	Peptidase M50
FFI11_RS12685	COG1222	aaa ATPase
FFI11_RS12690	COG4122	O-methyltransferase activity
FFI11_RS12700	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FFI11_RS12705	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FFI11_RS12710	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FFI11_RS12720	COG0107	imidazoleglycerol-phosphate synthase activity
FFI11_RS12730	COG1132	(ABC) transporter
FFI11_RS12735	COG1132	(ABC) transporter
FFI11_RS12740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FFI11_RS12770	COG0134	indole-3-glycerol-phosphate synthase activity
FFI11_RS12775	COG0133	tryptophan synthase activity
FFI11_RS12780	COG0159	tryptophan synthase activity
FFI11_RS12785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FFI11_RS12790	COG0069	glutamate synthase activity
FFI11_RS12790	COG0067	glutamate synthase
FFI11_RS12790	COG0070	glutamate synthase
FFI11_RS12805	COG3541	Predicted nucleotidyltransferase
FFI11_RS12835	COG1780	Probably involved in ribonucleotide reductase function
FFI11_RS12840	COG1280	lysine exporter protein (LysE YggA)
FFI11_RS12845	COG1053	succinate dehydrogenase
FFI11_RS12860	COG1472	Belongs to the glycosyl hydrolase 3 family
FFI11_RS12870	COG1216	Glycosyl transferase, family 2
FFI11_RS12940	COG2050	protein possibly involved in aromatic compounds catabolism
FFI11_RS12955	COG2226	methyltransferase
FFI11_RS12965	COG0539	negative regulation of cytoplasmic translation
FFI11_RS12975	COG1132	(ABC) transporter
FFI11_RS12985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FFI11_RS12985	COG0237	dephospho-CoA kinase activity
FFI11_RS12990	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FFI11_RS13000	COG0556	nucleotide-excision repair
FFI11_RS13025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFI11_RS13040	COG0322	excinuclease ABC activity
FFI11_RS13050	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FFI11_RS13055	COG1481	regulation of sporulation
FFI11_RS13060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FFI11_RS13065	COG0126	phosphoglycerate kinase activity
FFI11_RS13070	COG0149	triose-phosphate isomerase activity
FFI11_RS13075	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFI11_RS13085	COG0363	glucosamine-6-phosphate deaminase activity
FFI11_RS13100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FFI11_RS13110	COG0109	protoheme IX farnesyltransferase activity
FFI11_RS13125	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FFI11_RS13130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FFI11_RS13135	COG1187	pseudouridine synthase activity
FFI11_RS13140	COG4401	Chorismate mutase type I
FFI11_RS13145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FFI11_RS13155	COG1160	GTP binding
FFI11_RS13175	COG0640	Transcriptional regulator
FFI11_RS13185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FFI11_RS13190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FFI11_RS13195	COG0798	PFAM Bile acid sodium symporter
FFI11_RS13210	COG2267	carboxylic ester hydrolase activity
FFI11_RS13215	COG4585	Histidine kinase
FFI11_RS13220	COG2197	response regulator
FFI11_RS13225	COG1846	Transcriptional regulator
FFI11_RS13255	COG0783	Belongs to the Dps family
FFI11_RS13260	COG3973	AAA domain
FFI11_RS13265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FFI11_RS13275	COG3684	Belongs to the aldolase LacD family
FFI11_RS13300	COG1175	transmembrane transport
FFI11_RS13305	COG0395	ABC-type sugar transport system, permease component
FFI11_RS13310	COG3250	beta-galactosidase activity
FFI11_RS13330	COG1609	Transcriptional regulator
FFI11_RS13335	COG1940	carbohydrate kinase activity
FFI11_RS13340	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FFI11_RS13355	COG3395	kinase activity
FFI11_RS13360	COG0235	Class ii aldolase
FFI11_RS13365	COG2409	Drug exporters of the RND superfamily
FFI11_RS13385	COG3483	tryptophan 2,3-dioxygenase activity
FFI11_RS13405	COG0706	membrane insertase activity
FFI11_RS13410	COG1643	Atp-dependent helicase
FFI11_RS13425	COG2239	Acts as a magnesium transporter
FFI11_RS13475	COG1028	Short-chain dehydrogenase reductase Sdr
FFI11_RS13490	COG0009	L-threonylcarbamoyladenylate synthase
FFI11_RS13510	COG1739	Uncharacterized protein family UPF0029
FFI11_RS13535	COG0714	Associated with various cellular activities
FFI11_RS13570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFI11_RS13575	COG0805	protein transport
FFI11_RS13580	COG1597	lipid kinase activity
FFI11_RS13590	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FFI11_RS13610	COG4974	Belongs to the 'phage' integrase family
FFI11_RS13640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FFI11_RS13655	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FFI11_RS13660	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FFI11_RS13730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FFI11_RS13735	COG0140	phosphoribosyl-ATP diphosphatase activity
FFI11_RS13740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FFI11_RS13745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFI11_RS13745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFI11_RS13760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FFI11_RS13770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FFI11_RS13775	COG1011	Hydrolase
FFI11_RS13785	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FFI11_RS13795	COG1758	RNA polymerase activity
FFI11_RS13800	COG0194	GDP metabolic process
FFI11_RS13805	COG0322	excinuclease ABC activity
FFI11_RS13810	COG2365	Tyrosine phosphatase family
FFI11_RS13815	COG0284	orotidine-5'-phosphate decarboxylase activity
FFI11_RS13820	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FFI11_RS13835	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FFI11_RS13840	COG0540	Belongs to the ATCase OTCase family
FFI11_RS13845	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FFI11_RS13850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FFI11_RS13855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FFI11_RS13870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FFI11_RS13890	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FFI11_RS13895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FFI11_RS13900	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FFI11_RS13910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FFI11_RS13915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FFI11_RS13920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FFI11_RS13925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FFI11_RS13940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FFI11_RS13950	COG2409	Drug exporters of the RND superfamily
FFI11_RS13960	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FFI11_RS13965	COG3467	pyridoxamine 5'-phosphate
FFI11_RS13975	COG0124	histidyl-tRNA synthetase
FFI11_RS13990	COG1196	nuclear chromosome segregation
FFI11_RS14005	COG1793	dna ligase
FFI11_RS14010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FFI11_RS14015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFI11_RS14020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFI11_RS14025	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFI11_RS14035	COG2255	four-way junction helicase activity
FFI11_RS14040	COG0632	four-way junction helicase activity
FFI11_RS14050	COG0217	transcriptional regulatory protein
FFI11_RS14055	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FFI11_RS14060	COG0494	nUDIX hydrolase
FFI11_RS14065	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FFI11_RS14075	COG0438	transferase activity, transferring glycosyl groups
FFI11_RS14080	COG1560	Kdo2-lipid A biosynthetic process
FFI11_RS14085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FFI11_RS14095	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FFI11_RS14120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFI11_RS14125	COG1181	Belongs to the D-alanine--D-alanine ligase family
FFI11_RS14135	COG2197	response regulator
FFI11_RS14155	COG2318	DinB family
FFI11_RS14165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FFI11_RS14165	COG0519	Catalyzes the synthesis of GMP from XMP
FFI11_RS14175	COG1328	CTP reductase activity
FFI11_RS14180	COG0602	queuosine metabolic process
FFI11_RS14225	COG0534	Mate efflux family protein
FFI11_RS14305	COG2326	polyphosphate kinase activity
FFI11_RS14335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FFI11_RS14355	COG0183	Belongs to the thiolase family
FFI11_RS14360	COG1250	3-hydroxyacyl-CoA dehydrogenase
FFI11_RS14360	COG1024	Enoyl-CoA hydratase
FFI11_RS14370	COG5504	Zn-dependent protease
FFI11_RS14380	COG0531	amino acid
FFI11_RS14385	COG0477	Major facilitator Superfamily
FFI11_RS14390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FFI11_RS14415	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FFI11_RS14445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FFI11_RS14450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FFI11_RS14455	COG0598	Magnesium transport protein CorA
FFI11_RS14460	COG0463	Glycosyl transferase, family 2
FFI11_RS14465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FFI11_RS14470	COG0531	amino acid
FFI11_RS14475	COG0569	domain protein
FFI11_RS14500	COG0756	dUTP diphosphatase activity
FFI11_RS14520	COG2860	membrane
FFI11_RS14530	COG1435	thymidine kinase activity
FFI11_RS14555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FFI11_RS14570	COG0646	methionine synthase
FFI11_RS14570	COG1410	methionine synthase
FFI11_RS14580	COG3707	response regulator
FFI11_RS14620	COG0187	DNA topoisomerase II activity
FFI11_RS14630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFI11_RS14635	COG0589	response to stress
FFI11_RS14650	COG0142	geranyltranstransferase activity
FFI11_RS14660	COG2815	serine threonine protein kinase
FFI11_RS14660	COG0515	serine threonine protein kinase
FFI11_RS14665	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FFI11_RS14685	COG1940	carbohydrate kinase activity
FFI11_RS14690	COG1022	Amp-dependent synthetase and ligase
FFI11_RS14710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FFI11_RS14720	COG1845	cytochrome c oxidase, subunit III
FFI11_RS14725	COG2010	Cytochrome c
FFI11_RS14730	COG0723	plastoquinol--plastocyanin reductase activity
FFI11_RS14735	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FFI11_RS14755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FFI11_RS14760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FFI11_RS14765	COG1104	cysteine desulfurase activity
FFI11_RS14770	COG0425	Belongs to the sulfur carrier protein TusA family
FFI11_RS14785	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FFI11_RS14795	COG2409	Drug exporters of the RND superfamily
FFI11_RS14805	COG2329	Antibiotic biosynthesis monooxygenase
FFI11_RS14835	COG0667	Aldo Keto reductase
FFI11_RS14860	COG2045	Belongs to the ComB family
FFI11_RS14870	COG0167	dihydroorotate dehydrogenase activity
FFI11_RS14885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FFI11_RS14895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFI11_RS14900	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFI11_RS14915	COG0673	inositol 2-dehydrogenase activity
FFI11_RS14925	COG2409	Drug exporters of the RND superfamily
FFI11_RS14930	COG1846	Transcriptional regulator
FFI11_RS14945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FFI11_RS14980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFI11_RS14985	COG1366	Belongs to the anti-sigma-factor antagonist family
FFI11_RS14990	COG1366	Belongs to the anti-sigma-factor antagonist family
FFI11_RS14995	COG2172	sigma factor antagonist activity
FFI11_RS15005	COG2198	Histidine kinase
FFI11_RS15005	COG0784	Response regulator, receiver
FFI11_RS15005	COG5002	protein histidine kinase activity
FFI11_RS15010	COG0745	RESPONSE REGULATOR receiver
FFI11_RS15040	COG1302	Protein conserved in bacteria
FFI11_RS15045	COG1595	DNA-templated transcription, initiation
FFI11_RS15075	COG3546	catalase activity
FFI11_RS15080	COG0531	amino acid
FFI11_RS15105	COG1295	ribonuclease BN
FFI11_RS15125	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FFI11_RS15130	COG0659	secondary active sulfate transmembrane transporter activity
FFI11_RS15135	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FFI11_RS15140	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FFI11_RS15140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FFI11_RS15190	COG3119	arylsulfatase activity
FFI11_RS15195	COG2909	trisaccharide binding
FFI11_RS15230	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FFI11_RS15235	COG0174	glutamine synthetase
FFI11_RS15240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFI11_RS15240	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FFI11_RS15245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FFI11_RS15250	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFI11_RS15290	COG1401	restriction endodeoxyribonuclease activity
FFI11_RS15310	COG3022	response to hydroperoxide
FFI11_RS15335	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FFI11_RS15345	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFI11_RS15345	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFI11_RS15360	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FFI11_RS15370	COG0714	Associated with various cellular activities
FFI11_RS15375	COG3831	ATPase activity
FFI11_RS15385	COG1309	transcriptional regulator
FFI11_RS15410	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FFI11_RS15430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FFI11_RS15435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFI11_RS15440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFI11_RS15495	COG0358	DNA primase activity
FFI11_RS15510	COG3550	peptidyl-serine autophosphorylation
FFI11_RS15530	COG3833	ABC-type maltose transport systems, permease component
FFI11_RS15535	COG1175	transmembrane transport
FFI11_RS15550	COG0366	Alpha amylase catalytic
FFI11_RS15560	COG0423	glycine-tRNA ligase activity
FFI11_RS15570	COG1121	(ABC) transporter
FFI11_RS15575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFI11_RS15595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FFI11_RS15600	COG1381	Involved in DNA repair and RecF pathway recombination
FFI11_RS15605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FFI11_RS15630	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FFI11_RS15640	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FFI11_RS15650	COG0537	adenosine 5'-monophosphoramidase activity
FFI11_RS15660	COG0484	heat shock protein binding
FFI11_RS15665	COG1420	regulation of RNA biosynthetic process
FFI11_RS15690	COG2755	lipolytic protein G-D-S-L family
FFI11_RS15690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FFI11_RS15700	COG0481	GTPase activity
FFI11_RS15710	COG0268	Binds directly to 16S ribosomal RNA
FFI11_RS15715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFI11_RS15715	COG0456	acetyltransferase
FFI11_RS15735	COG1307	EDD domain protein, DegV family
FFI11_RS15740	COG0433	COG0433 Predicted ATPase
FFI11_RS15770	COG2814	Major facilitator Superfamily
FFI11_RS15780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFI11_RS15785	COG1121	(ABC) transporter
FFI11_RS15800	COG0477	Major facilitator Superfamily
FFI11_RS15815	COG2186	Transcriptional regulator
FFI11_RS15820	COG4166	transmembrane transport
FFI11_RS15835	COG4608	Belongs to the ABC transporter superfamily
FFI11_RS15840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFI11_RS15845	COG1940	carbohydrate kinase activity
FFI11_RS15850	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FFI11_RS15860	COG1569	PIN domain
FFI11_RS15865	COG3311	Transcriptional regulator
FFI11_RS15875	COG4702	Belongs to the UPF0303 family
FFI11_RS15880	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FFI11_RS15890	COG2357	RelA SpoT domain protein
FFI11_RS15910	COG1309	transcriptional regulator
FFI11_RS15945	COG0006	proline dipeptidase activity
FFI11_RS15970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FFI11_RS15980	COG0259	pyridoxamine-phosphate oxidase activity
FFI11_RS15990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFI11_RS15990	COG2146	nitrite reductase [NAD(P)H] activity
FFI11_RS15995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFI11_RS16000	COG0579	oxidoreductase
FFI11_RS16020	COG4977	sequence-specific DNA binding
FFI11_RS16025	COG0656	L-ascorbic acid biosynthetic process
FFI11_RS16030	COG2084	Dehydrogenase
FFI11_RS16045	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FFI11_RS16050	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FFI11_RS16065	COG0406	alpha-ribazole phosphatase activity
FFI11_RS16070	COG0799	negative regulation of ribosome biogenesis
FFI11_RS16080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FFI11_RS16085	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FFI11_RS16090	COG0667	Aldo Keto reductase
FFI11_RS16105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFI11_RS16110	COG0601	transmembrane transport
FFI11_RS16115	COG0747	negative chemotaxis
FFI11_RS16120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FFI11_RS16130	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FFI11_RS16135	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FFI11_RS16140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FFI11_RS16160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFI11_RS16170	COG0076	glutamate decarboxylase activity
FFI11_RS16185	COG2326	polyphosphate kinase activity
FFI11_RS16190	COG0488	(ABC) transporter
FFI11_RS16200	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FFI11_RS16205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FFI11_RS16210	COG1234	tRNA 3'-trailer cleavage
FFI11_RS16215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FFI11_RS16245	COG0363	glucosamine-6-phosphate deaminase activity
FFI11_RS16255	COG0395	ABC-type sugar transport system, permease component
FFI11_RS16260	COG1175	transmembrane transport
FFI11_RS16270	COG1846	Transcriptional regulator
FFI11_RS16270	COG1940	carbohydrate kinase activity
FFI11_RS16305	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FFI11_RS16315	COG2177	Part of the ABC transporter FtsEX involved in
FFI11_RS16325	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FFI11_RS16385	COG2814	Major facilitator Superfamily
FFI11_RS16395	COG1695	Transcriptional regulator
FFI11_RS16400	COG2135	peptidase activity
FFI11_RS16415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FFI11_RS16435	COG0424	maF-like protein
FFI11_RS16440	COG4770	biotin carboxylase activity
FFI11_RS16460	COG2076	Multidrug Resistance protein
FFI11_RS16480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FFI11_RS16490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FFI11_RS16505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFI11_RS16510	COG0697	spore germination
FFI11_RS16525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FFI11_RS16545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FFI11_RS16565	COG2149	membrane
FFI11_RS16580	COG1079	Belongs to the binding-protein-dependent transport system permease family
FFI11_RS16585	COG4603	Belongs to the binding-protein-dependent transport system permease family
FFI11_RS16590	COG3845	ABC transporter
FFI11_RS16595	COG1744	ABC transporter substrate-binding protein PnrA-like
FFI11_RS16600	COG1473	amidohydrolase
FFI11_RS16600	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FFI11_RS16610	COG2009	succinate dehydrogenase
FFI11_RS16625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FFI11_RS16640	COG0180	Tryptophanyl-tRNA synthetase
FFI11_RS16650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFI11_RS16660	COG1595	DNA-templated transcription, initiation
FFI11_RS16670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FFI11_RS16685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FFI11_RS16690	COG1611	Belongs to the LOG family
FFI11_RS16695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFI11_RS16735	COG0287	Prephenate dehydrogenase
FFI11_RS16760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FFI11_RS16765	COG1217	gtp-binding protein TYPA
FFI11_RS16770	COG4172	Belongs to the ABC transporter superfamily
FFI11_RS16780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFI11_RS16795	COG0012	GTP binding
FFI11_RS16810	COG1322	Protein conserved in bacteria
FFI11_RS16820	COG1570	exodeoxyribonuclease VII activity
FFI11_RS16825	COG1722	exodeoxyribonuclease VII activity
FFI11_RS16850	COG0288	reversible hydration of carbon dioxide
FFI11_RS16855	COG0114	fumarate hydratase activity
FFI11_RS16860	COG2314	TM2 domain
FFI11_RS16880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FFI11_RS16895	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FFI11_RS16910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FFI11_RS16945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFI11_RS16960	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FFI11_RS17015	COG3304	Inner membrane component domain
FFI11_RS17020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FFI11_RS17025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FFI11_RS17030	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FFI11_RS17035	COG1472	Belongs to the glycosyl hydrolase 3 family
FFI11_RS17040	COG0395	ABC-type sugar transport system, permease component
FFI11_RS17050	COG2182	Extracellular solute-binding protein
FFI11_RS17055	COG0095	Lipoate-protein ligase
FFI11_RS17065	COG1737	Transcriptional regulator
FFI11_RS17070	COG0277	FAD linked oxidase domain protein
FFI11_RS17075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FFI11_RS17085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFI11_RS17090	COG0473	3-isopropylmalate dehydrogenase activity
FFI11_RS17105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FFI11_RS17110	COG0440	acetolactate synthase activity
FFI11_RS17125	COG1131	(ABC) transporter
FFI11_RS17135	COG2154	pterin-4-alpha-carbinolamine dehydratase
FFI11_RS17140	COG0129	dihydroxy-acid dehydratase activity
FFI11_RS17150	COG0129	dihydroxy-acid dehydratase activity
FFI11_RS17160	COG3104	oligopeptide transport
FFI11_RS17165	COG0415	Belongs to the DNA photolyase family
FFI11_RS17175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FFI11_RS17180	COG0154	amidase activity
FFI11_RS17185	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FFI11_RS17215	COG1984	allophanate hydrolase subunit 2
FFI11_RS17220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FFI11_RS17265	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFI11_RS17270	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFI11_RS17275	COG1129	ABC transporter
FFI11_RS17280	COG0673	inositol 2-dehydrogenase activity
FFI11_RS17305	COG1879	ABC-type sugar transport system periplasmic component
FFI11_RS17310	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFI11_RS17315	COG1129	ABC transporter
FFI11_RS17320	COG1940	carbohydrate kinase activity
FFI11_RS17340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FFI11_RS17345	COG1012	belongs to the aldehyde dehydrogenase family
FFI11_RS17345	COG1454	alcohol dehydrogenase
FFI11_RS17350	COG1505	serine-type exopeptidase activity
FFI11_RS17365	COG0577	efflux transmembrane transporter activity
FFI11_RS17365	COG1136	(ABC) transporter
FFI11_RS17370	COG1136	(ABC) transporter
FFI11_RS17370	COG0577	efflux transmembrane transporter activity
FFI11_RS17385	COG0745	RESPONSE REGULATOR receiver
FFI11_RS17390	COG2205	protein histidine kinase activity
FFI11_RS17405	COG0482	sulfurtransferase activity
FFI11_RS17420	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FFI11_RS17460	COG0366	Alpha amylase catalytic
FFI11_RS17480	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FFI11_RS17510	COG0596	Alpha beta hydrolase
FFI11_RS17510	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFI11_RS17525	COG0545	Peptidyl-prolyl cis-trans isomerase
FFI11_RS17535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFI11_RS17545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFI11_RS17550	COG1780	Probably involved in ribonucleotide reductase function
FFI11_RS17565	COG1501	Belongs to the glycosyl hydrolase 31 family
FFI11_RS17570	COG0395	ABC-type sugar transport system, permease component
FFI11_RS17575	COG4209	transmembrane transport
FFI11_RS17610	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FFI11_RS17620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FFI11_RS17625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FFI11_RS17630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FFI11_RS17635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FFI11_RS17640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FFI11_RS17655	COG0356	it plays a direct role in the translocation of protons across the membrane
FFI11_RS17675	COG2890	protein-(glutamine-N5) methyltransferase activity
FFI11_RS17680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FFI11_RS17685	COG0254	rRNA binding
FFI11_RS17695	COG0083	homoserine kinase activity
FFI11_RS17700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FFI11_RS17705	COG0460	homoserine dehydrogenase
FFI11_RS17715	COG0019	diaminopimelate decarboxylase activity
FFI11_RS17720	COG0018	arginyl-trna synthetase
FFI11_RS17725	COG2807	transmembrane transport
FFI11_RS17765	COG1253	flavin adenine dinucleotide binding
FFI11_RS17770	COG0745	RESPONSE REGULATOR receiver
FFI11_RS17775	COG2205	protein histidine kinase activity
FFI11_RS17780	COG0567	Dehydrogenase, E1 component
FFI11_RS17780	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFI11_RS17790	COG2017	converts alpha-aldose to the beta-anomer
FFI11_RS17820	COG1595	DNA-templated transcription, initiation
FFI11_RS17835	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FFI11_RS17840	COG1162	GTPase activity
FFI11_RS17845	COG0483	inositol monophosphate 1-phosphatase activity
FFI11_RS17885	COG0653	protein targeting
FFI11_RS17890	COG3214	Protein conserved in bacteria
FFI11_RS17895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FFI11_RS17910	COG5002	protein histidine kinase activity
FFI11_RS17915	COG0745	RESPONSE REGULATOR receiver
FFI11_RS17935	COG0714	Associated with various cellular activities
FFI11_RS17980	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FFI11_RS17990	COG0517	IMP dehydrogenase activity
FFI11_RS17990	COG4175	Glycine betaine
FFI11_RS18050	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FFI11_RS18060	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FFI11_RS18075	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FFI11_RS18075	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FFI11_RS18110	COG1216	Glycosyl transferase, family 2
FFI11_RS18140	COG1216	Glycosyl transferase, family 2
FFI11_RS18180	COG1316	TRANSCRIPTIONal
FFI11_RS18190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FFI11_RS18205	COG2205	protein histidine kinase activity
FFI11_RS18210	COG0745	RESPONSE REGULATOR receiver
FFI11_RS18215	COG4585	Histidine kinase
FFI11_RS18220	COG2197	response regulator
FFI11_RS18225	COG4591	ABC-type transport system involved in lipoprotein release permease component
FFI11_RS18225	COG1136	(ABC) transporter
FFI11_RS18265	COG3833	ABC-type maltose transport systems, permease component
FFI11_RS18270	COG2723	6-phospho-beta-galactosidase activity
FFI11_RS18290	COG1012	belongs to the aldehyde dehydrogenase family
FFI11_RS18310	COG0656	L-ascorbic acid biosynthetic process
FFI11_RS18315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FFI11_RS18330	COG3253	May function as heme-dependent peroxidase
FFI11_RS18335	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FFI11_RS18340	COG0395	ABC-type sugar transport system, permease component
FFI11_RS18345	COG4209	transmembrane transport
FFI11_RS18355	COG0366	Alpha amylase catalytic
FFI11_RS18370	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FFI11_RS18375	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FFI11_RS18380	COG1414	Transcriptional regulator
FFI11_RS18400	COG1929	Belongs to the glycerate kinase type-1 family
FFI11_RS18410	COG1785	Belongs to the alkaline phosphatase family
FFI11_RS18425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FFI11_RS18435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFI11_RS18445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FFI11_RS18455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFI11_RS18470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FFI11_RS18485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFI11_RS18510	COG0640	Transcriptional regulator
FFI11_RS18540	COG2813	Specifically methylates the guanine in position
FFI11_RS18550	COG3387	PFAM Glycoside hydrolase 15-related
FFI11_RS18600	COG2197	response regulator
FFI11_RS18610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFI11_RS18640	COG0740	serine-type endopeptidase activity
FFI11_RS18645	COG0740	serine-type endopeptidase activity
FFI11_RS18655	COG1396	sequence-specific DNA binding
FFI11_RS18680	COG1252	NADH dehydrogenase
FFI11_RS18720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFI11_RS18735	COG0148	phosphopyruvate hydratase activity
FFI11_RS18755	COG0444	Belongs to the ABC transporter superfamily
FFI11_RS18760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFI11_RS18765	COG0601	transmembrane transport
FFI11_RS18770	COG0747	negative chemotaxis
FFI11_RS18815	COG0297	glycogen (starch) synthase activity
FFI11_RS18895	COG1216	Glycosyl transferase, family 2
FFI11_RS18900	COG0438	transferase activity, transferring glycosyl groups
FFI11_RS18910	COG0438	transferase activity, transferring glycosyl groups
FFI11_RS18925	COG0489	protein tyrosine kinase activity
FFI11_RS18935	COG0193	aminoacyl-tRNA hydrolase activity
FFI11_RS18940	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FFI11_RS18960	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FFI11_RS18970	COG1309	transcriptional regulator
FFI11_RS18975	COG4152	abc transporter atp-binding protein
FFI11_RS18990	COG0488	(ABC) transporter
FFI11_RS18995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FFI11_RS19000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FFI11_RS19010	COG3583	domain protein
FFI11_RS19020	COG0084	hydrolase, TatD family'
FFI11_RS19025	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFI11_RS19035	COG0436	Aminotransferase
FFI11_RS19050	COG1335	isochorismatase
FFI11_RS19140	COG1970	mechanosensitive ion channel activity
FFI11_RS19160	COG0657	acetylesterase activity
FFI11_RS19175	COG1136	(ABC) transporter
FFI11_RS19175	COG0577	efflux transmembrane transporter activity
FFI11_RS19180	COG1136	(ABC) transporter
FFI11_RS19190	COG0745	RESPONSE REGULATOR receiver
FFI11_RS19195	COG2205	protein histidine kinase activity
FFI11_RS19210	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FFI11_RS19240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FFI11_RS19245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFI11_RS19265	COG3103	Sh3 type 3 domain protein
FFI11_RS19265	COG1388	LysM domain
FFI11_RS19265	COG0791	NLP P60 protein
FFI11_RS19275	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FFI11_RS19280	COG2814	Major facilitator Superfamily
FFI11_RS19300	COG1316	TRANSCRIPTIONal
FFI11_RS19310	COG0438	transferase activity, transferring glycosyl groups
FFI11_RS19325	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FFI11_RS19340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process