locus-tag	class	description
EKN16_RS00020	COG0395	ABC-type sugar transport system, permease component
EKN16_RS00040	COG0395	ABC-type sugar transport system, permease component
EKN16_RS00050	COG1301	dicarboxylic acid transport
EKN16_RS00065	COG3290	protein histidine kinase activity
EKN16_RS00070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EKN16_RS00095	COG0701	Predicted permease
EKN16_RS00110	COG0288	reversible hydration of carbon dioxide
EKN16_RS00120	COG0673	inositol 2-dehydrogenase activity
EKN16_RS00135	COG1216	Glycosyl transferase, family 2
EKN16_RS00135	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS00140	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EKN16_RS00150	COG1215	transferase activity, transferring glycosyl groups
EKN16_RS00190	COG0583	DNA-binding transcription factor activity
EKN16_RS00205	COG1388	LysM domain
EKN16_RS00205	COG4641	Protein conserved in bacteria
EKN16_RS00210	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS00225	COG1091	dTDP-4-dehydrorhamnose reductase activity
EKN16_RS00235	COG1216	Glycosyl transferase, family 2
EKN16_RS00245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKN16_RS00265	COG2197	response regulator
EKN16_RS00295	COG3275	phosphorelay sensor kinase activity
EKN16_RS00300	COG2207	Transcriptional regulator
EKN16_RS00300	COG4753	response regulator
EKN16_RS00310	COG4209	transmembrane transport
EKN16_RS00315	COG0395	ABC-type sugar transport system, permease component
EKN16_RS00325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EKN16_RS00330	COG1494	fructose-1,6-bisphosphatase
EKN16_RS00335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EKN16_RS00345	COG2814	Major facilitator Superfamily
EKN16_RS00350	COG2066	Belongs to the glutaminase family
EKN16_RS00360	COG3290	protein histidine kinase activity
EKN16_RS00365	COG4715	Zinc finger, swim domain protein
EKN16_RS00370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EKN16_RS00380	COG0667	Aldo Keto reductase
EKN16_RS00390	COG0477	Major facilitator Superfamily
EKN16_RS00395	COG2318	DinB family
EKN16_RS00405	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EKN16_RS00415	COG0385	Bile acid
EKN16_RS00420	COG5002	protein histidine kinase activity
EKN16_RS00425	COG0745	RESPONSE REGULATOR receiver
EKN16_RS00435	COG0673	inositol 2-dehydrogenase activity
EKN16_RS00440	COG1294	oxidase, subunit
EKN16_RS00445	COG1271	oxidase subunit
EKN16_RS00450	COG0697	spore germination
EKN16_RS00455	COG0814	amino acid
EKN16_RS00470	COG0584	glycerophosphoryl diester phosphodiesterase
EKN16_RS00490	COG3279	Response regulator of the LytR AlgR family
EKN16_RS00505	COG1309	transcriptional regulator
EKN16_RS00520	COG2040	homocysteine
EKN16_RS00530	COG1802	Transcriptional regulator
EKN16_RS00535	COG0626	cystathionine gamma-synthase activity
EKN16_RS00545	COG1012	belongs to the aldehyde dehydrogenase family
EKN16_RS00550	COG1027	Aspartate ammonia-lyase
EKN16_RS00555	COG0833	amino acid
EKN16_RS00565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKN16_RS00575	COG0745	RESPONSE REGULATOR receiver
EKN16_RS00580	COG5002	protein histidine kinase activity
EKN16_RS00590	COG2267	carboxylic ester hydrolase activity
EKN16_RS00595	COG3226	Transcriptional regulator
EKN16_RS00635	COG4209	transmembrane transport
EKN16_RS00640	COG0395	ABC-type sugar transport system, permease component
EKN16_RS00650	COG2972	Histidine kinase
EKN16_RS00660	COG2207	Transcriptional regulator
EKN16_RS00690	COG3266	domain, Protein
EKN16_RS00690	COG2911	Protein conserved in bacteria
EKN16_RS00690	COG1361	Conserved repeat domain
EKN16_RS00705	COG0488	(ABC) transporter
EKN16_RS00730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKN16_RS00750	COG4209	transmembrane transport
EKN16_RS00755	COG0395	ABC-type sugar transport system, permease component
EKN16_RS00765	COG5652	VanZ like family
EKN16_RS00775	COG1361	Conserved repeat domain
EKN16_RS00780	COG4753	response regulator
EKN16_RS00780	COG2207	Transcriptional regulator
EKN16_RS00785	COG2972	Histidine kinase
EKN16_RS00790	COG0753	catalase activity
EKN16_RS00800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKN16_RS00835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKN16_RS00840	COG2169	Transcriptional regulator
EKN16_RS00850	COG4191	Histidine kinase
EKN16_RS00855	COG1607	acyl-coa hydrolase
EKN16_RS00880	COG0395	ABC-type sugar transport system, permease component
EKN16_RS00900	COG0697	spore germination
EKN16_RS00910	COG0726	polysaccharide deacetylase
EKN16_RS00920	COG1940	carbohydrate kinase activity
EKN16_RS00945	COG1940	carbohydrate kinase activity
EKN16_RS00955	COG3275	phosphorelay sensor kinase activity
EKN16_RS00960	COG2207	Transcriptional regulator
EKN16_RS00960	COG4753	response regulator
EKN16_RS00970	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EKN16_RS01000	COG4209	transmembrane transport
EKN16_RS01005	COG0395	ABC-type sugar transport system, permease component
EKN16_RS01015	COG3345	alpha-galactosidase
EKN16_RS01035	COG0583	DNA-binding transcription factor activity
EKN16_RS01040	COG1902	pentaerythritol trinitrate reductase activity
EKN16_RS01050	COG1309	transcriptional regulator
EKN16_RS01055	COG3844	kynureninase activity
EKN16_RS01060	COG1113	amino acid transport
EKN16_RS01065	COG1361	Conserved repeat domain
EKN16_RS01075	COG2169	Transcriptional regulator
EKN16_RS01075	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS01085	COG4753	response regulator
EKN16_RS01085	COG2207	Transcriptional regulator
EKN16_RS01090	COG4209	transmembrane transport
EKN16_RS01095	COG0395	ABC-type sugar transport system, permease component
EKN16_RS01100	COG1653	transport
EKN16_RS01105	COG1472	Belongs to the glycosyl hydrolase 3 family
EKN16_RS01120	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS01120	COG2207	Transcriptional regulator
EKN16_RS01130	COG3706	GGDEF domain
EKN16_RS01145	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS01150	COG1349	DNA-binding transcription factor activity
EKN16_RS01155	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EKN16_RS01205	COG1309	transcriptional regulator
EKN16_RS01245	COG1361	Conserved repeat domain
EKN16_RS01255	COG2373	Large extracellular alpha-helical protein
EKN16_RS01265	COG3588	fructose-bisphosphate aldolase
EKN16_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS01280	COG3347	Dehydrogenase
EKN16_RS01290	COG4806	L-rhamnose isomerase
EKN16_RS01295	COG1070	Carbohydrate kinase
EKN16_RS01300	COG1349	DNA-binding transcription factor activity
EKN16_RS01305	COG0247	lactate metabolic process
EKN16_RS01310	COG1139	Iron-sulfur cluster binding protein
EKN16_RS01315	COG1556	Lactate utilization protein
EKN16_RS01320	COG2186	Transcriptional regulator
EKN16_RS01335	COG2357	RelA SpoT domain protein
EKN16_RS01345	COG2207	Transcriptional regulator
EKN16_RS01345	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS01355	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EKN16_RS01360	COG0586	Pfam SNARE associated Golgi protein
EKN16_RS01370	COG0656	L-ascorbic acid biosynthetic process
EKN16_RS01375	COG0657	acetylesterase activity
EKN16_RS01375	COG2755	lipolytic protein G-D-S-L family
EKN16_RS01385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EKN16_RS01410	COG0673	inositol 2-dehydrogenase activity
EKN16_RS01415	COG1414	Transcriptional regulator
EKN16_RS01420	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS01435	COG2814	Major facilitator Superfamily
EKN16_RS01450	COG0573	inorganic phosphate transmembrane transporter activity
EKN16_RS01455	COG0581	inorganic phosphate transmembrane transporter activity
EKN16_RS01470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EKN16_RS01475	COG0704	Plays a role in the regulation of phosphate uptake
EKN16_RS01485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EKN16_RS01490	COG0573	inorganic phosphate transmembrane transporter activity
EKN16_RS01495	COG0581	inorganic phosphate transmembrane transporter activity
EKN16_RS01500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EKN16_RS01505	COG0704	Plays a role in the regulation of phosphate uptake
EKN16_RS01525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EKN16_RS01530	COG1971	Probably functions as a manganese efflux pump
EKN16_RS01535	COG0237	dephospho-CoA kinase activity
EKN16_RS01540	COG0739	heme binding
EKN16_RS01540	COG0741	lytic transglycosylase activity
EKN16_RS01540	COG1196	nuclear chromosome segregation
EKN16_RS01550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EKN16_RS01565	COG0488	(ABC) transporter
EKN16_RS01570	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EKN16_RS01615	COG1940	carbohydrate kinase activity
EKN16_RS01620	COG0673	inositol 2-dehydrogenase activity
EKN16_RS01625	COG3842	ATPase activity
EKN16_RS01630	COG1653	transport
EKN16_RS01640	COG0395	ABC-type sugar transport system, permease component
EKN16_RS01660	COG1175	transmembrane transport
EKN16_RS01665	COG0395	ABC-type sugar transport system, permease component
EKN16_RS01695	COG4585	Histidine kinase
EKN16_RS01700	COG4585	Histidine kinase
EKN16_RS01760	COG2814	Major facilitator Superfamily
EKN16_RS01765	COG1611	Belongs to the LOG family
EKN16_RS01770	COG0745	RESPONSE REGULATOR receiver
EKN16_RS01770	COG2972	Histidine kinase
EKN16_RS01775	COG2197	response regulator
EKN16_RS01785	COG4209	transmembrane transport
EKN16_RS01790	COG0395	ABC-type sugar transport system, permease component
EKN16_RS01800	COG2972	Histidine kinase
EKN16_RS01805	COG2207	Transcriptional regulator
EKN16_RS01805	COG4753	response regulator
EKN16_RS01815	COG1129	ABC transporter
EKN16_RS01820	COG1172	Belongs to the binding-protein-dependent transport system permease family
EKN16_RS01825	COG1172	Belongs to the binding-protein-dependent transport system permease family
EKN16_RS01860	COG1175	transmembrane transport
EKN16_RS01865	COG0395	ABC-type sugar transport system, permease component
EKN16_RS01870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EKN16_RS01880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EKN16_RS01885	COG0156	8-amino-7-oxononanoate synthase activity
EKN16_RS01895	COG4106	trans-aconitate 2-methyltransferase activity
EKN16_RS01900	COG0745	RESPONSE REGULATOR receiver
EKN16_RS01900	COG2972	Histidine kinase
EKN16_RS01905	COG3279	Response regulator of the LytR AlgR family
EKN16_RS01925	COG0395	ABC-type sugar transport system, permease component
EKN16_RS01930	COG4209	transmembrane transport
EKN16_RS01935	COG2972	Histidine kinase
EKN16_RS01950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS01960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS01985	COG0747	negative chemotaxis
EKN16_RS01990	COG0601	transmembrane transport
EKN16_RS01995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKN16_RS02000	COG0444	Belongs to the ABC transporter superfamily
EKN16_RS02025	COG2814	Major facilitator Superfamily
EKN16_RS02030	COG4977	sequence-specific DNA binding
EKN16_RS02045	COG2207	Transcriptional regulator
EKN16_RS02050	COG0492	ferredoxin-NADP+ reductase activity
EKN16_RS02055	COG1408	metallophosphoesterase
EKN16_RS02065	COG0018	arginyl-trna synthetase
EKN16_RS02070	COG1846	Transcriptional regulator
EKN16_RS02075	COG0778	Nitroreductase
EKN16_RS02080	COG1609	Transcriptional regulator
EKN16_RS02095	COG1070	Carbohydrate kinase
EKN16_RS02100	COG4154	Belongs to the RbsD FucU family
EKN16_RS02125	COG4824	toxin secretion phage lysis holin
EKN16_RS02150	COG2445	Protein of unknown function DUF86
EKN16_RS02170	COG0477	Major facilitator Superfamily
EKN16_RS02175	COG1846	Transcriptional regulator
EKN16_RS02185	COG1486	melibiose metabolic process
EKN16_RS02200	COG1131	(ABC) transporter
EKN16_RS02235	COG1368	sulfuric ester hydrolase activity
EKN16_RS02240	COG0116	Belongs to the methyltransferase superfamily
EKN16_RS02245	COG4122	O-methyltransferase activity
EKN16_RS02255	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EKN16_RS02260	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EKN16_RS02265	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EKN16_RS02290	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EKN16_RS02300	COG0697	spore germination
EKN16_RS02305	COG2814	Major facilitator Superfamily
EKN16_RS02330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EKN16_RS02340	COG3275	phosphorelay sensor kinase activity
EKN16_RS02345	COG4753	response regulator
EKN16_RS02345	COG2207	Transcriptional regulator
EKN16_RS02355	COG1175	transmembrane transport
EKN16_RS02360	COG0395	ABC-type sugar transport system, permease component
EKN16_RS02365	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS02370	COG1486	melibiose metabolic process
EKN16_RS02375	COG2017	converts alpha-aldose to the beta-anomer
EKN16_RS02380	COG0129	dihydroxy-acid dehydratase activity
EKN16_RS02395	COG3754	Rhamnan synthesis protein F
EKN16_RS02405	COG2207	Transcriptional regulator
EKN16_RS02405	COG4753	response regulator
EKN16_RS02410	COG3275	phosphorelay sensor kinase activity
EKN16_RS02430	COG0395	ABC-type sugar transport system, permease component
EKN16_RS02450	COG0673	inositol 2-dehydrogenase activity
EKN16_RS02455	COG3458	cephalosporin-C deacetylase activity
EKN16_RS02460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EKN16_RS02465	COG1609	Transcriptional regulator
EKN16_RS02480	COG0745	RESPONSE REGULATOR receiver
EKN16_RS02500	COG1175	transmembrane transport
EKN16_RS02520	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EKN16_RS02525	COG5401	PFAM Sporulation and spore germination
EKN16_RS02535	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EKN16_RS02540	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EKN16_RS02545	COG2746	aminoglycoside 3-N-acetyltransferase activity
EKN16_RS02550	COG1278	Cold shock
EKN16_RS02555	COG0367	asparagine synthase
EKN16_RS02570	COG0402	S-adenosylhomocysteine deaminase activity
EKN16_RS02575	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS02590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EKN16_RS02610	COG0544	peptidyl-prolyl cis-trans isomerase activity
EKN16_RS02615	COG0740	serine-type endopeptidase activity
EKN16_RS02620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EKN16_RS02630	COG0470	DNA polymerase III
EKN16_RS02630	COG1067	ATP-dependent peptidase activity
EKN16_RS02640	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EKN16_RS02650	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EKN16_RS02660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EKN16_RS02665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EKN16_RS02665	COG1648	precorrin-2 dehydrogenase activity
EKN16_RS02680	COG0113	porphobilinogen synthase activity
EKN16_RS02685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EKN16_RS02690	COG0564	pseudouridine synthase activity
EKN16_RS02695	COG1388	LysM domain
EKN16_RS02700	COG0525	valine-tRNA ligase activity
EKN16_RS02705	COG0285	dihydrofolate synthase activity
EKN16_RS02710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EKN16_RS02740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EKN16_RS02750	COG2207	Transcriptional regulator
EKN16_RS02750	COG3708	Transcriptional regulator
EKN16_RS02770	COG0745	RESPONSE REGULATOR receiver
EKN16_RS02775	COG5002	protein histidine kinase activity
EKN16_RS02775	COG3850	Histidine kinase
EKN16_RS02795	COG1136	(ABC) transporter
EKN16_RS02800	COG0577	efflux transmembrane transporter activity
EKN16_RS02805	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EKN16_RS02820	COG2318	DinB family
EKN16_RS02840	COG4221	oxidoreductase activity
EKN16_RS02845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKN16_RS02850	COG0667	Aldo Keto reductase
EKN16_RS02855	COG2207	Transcriptional regulator
EKN16_RS02890	COG0424	maF-like protein
EKN16_RS02895	COG2003	Belongs to the UPF0758 family
EKN16_RS02900	COG1077	Cell shape determining protein MreB Mrl
EKN16_RS02915	COG0850	regulation of cytokinetic process
EKN16_RS02920	COG2894	cell division
EKN16_RS02925	COG0772	Belongs to the SEDS family
EKN16_RS02935	COG1994	Peptidase M50
EKN16_RS02945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EKN16_RS02950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EKN16_RS02955	COG2868	ribosomal protein
EKN16_RS02970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EKN16_RS02975	COG4492	Belongs to the UPF0735 family
EKN16_RS02980	COG0460	homoserine dehydrogenase
EKN16_RS02985	COG0083	homoserine kinase activity
EKN16_RS02990	COG0077	Prephenate dehydratase
EKN16_RS03010	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EKN16_RS03015	COG0632	four-way junction helicase activity
EKN16_RS03020	COG2255	four-way junction helicase activity
EKN16_RS03030	COG2385	sporulation resulting in formation of a cellular spore
EKN16_RS03030	COG2385	sporulation resulting in formation of a cellular spore
EKN16_RS03035	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EKN16_RS03045	COG1862	Preprotein translocase
EKN16_RS03050	COG0671	phosphoesterase, PA-phosphatase related
EKN16_RS03065	COG2323	membrane
EKN16_RS03070	COG2244	polysaccharide biosynthetic process
EKN16_RS03080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKN16_RS03080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKN16_RS03085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKN16_RS03085	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKN16_RS03090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKN16_RS03095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EKN16_RS03095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EKN16_RS03100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKN16_RS03105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EKN16_RS03110	COG1490	D-aminoacyl-tRNA deacylase activity
EKN16_RS03115	COG0124	histidyl-tRNA synthetase
EKN16_RS03120	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EKN16_RS03125	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EKN16_RS03140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EKN16_RS03145	COG1253	flavin adenine dinucleotide binding
EKN16_RS03150	COG0482	sulfurtransferase activity
EKN16_RS03155	COG1959	2 iron, 2 sulfur cluster binding
EKN16_RS03160	COG1104	cysteine desulfurase activity
EKN16_RS03175	COG0628	permease
EKN16_RS03185	COG4472	Bacterial protein of unknown function (DUF965)
EKN16_RS03195	COG3906	Belongs to the UPF0473 family
EKN16_RS03205	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EKN16_RS03210	COG0826	peptidase U32
EKN16_RS03215	COG0826	peptidase U32
EKN16_RS03220	COG0840	transmembrane signaling receptor activity
EKN16_RS03225	COG2738	Putative neutral zinc metallopeptidase
EKN16_RS03230	COG0789	Transcriptional regulator
EKN16_RS03235	COG0004	ammonium transporteR
EKN16_RS03245	COG2176	DNA-directed DNA polymerase activity
EKN16_RS03255	COG2814	Major facilitator Superfamily
EKN16_RS03260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EKN16_RS03265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKN16_RS03270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKN16_RS03275	COG1141	Ferredoxin
EKN16_RS03295	COG1376	ErfK ybiS ycfS ynhG family protein
EKN16_RS03300	COG0167	dihydroorotate dehydrogenase activity
EKN16_RS03305	COG2357	RelA SpoT domain protein
EKN16_RS03315	COG1187	pseudouridine synthase activity
EKN16_RS03320	COG0561	phosphatase activity
EKN16_RS03380	COG0561	phosphatase activity
EKN16_RS03385	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EKN16_RS03400	COG2329	Antibiotic biosynthesis monooxygenase
EKN16_RS03440	COG0384	phenazine biosynthesis protein PhzF
EKN16_RS03460	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS03465	COG0420	3'-5' exonuclease activity
EKN16_RS03470	COG4717	serine-type aminopeptidase activity
EKN16_RS03475	COG3949	Membrane
EKN16_RS03485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKN16_RS03560	COG2207	Transcriptional regulator
EKN16_RS03560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS03565	COG1653	transport
EKN16_RS03570	COG4209	transmembrane transport
EKN16_RS03575	COG0395	ABC-type sugar transport system, permease component
EKN16_RS03585	COG2972	Histidine kinase
EKN16_RS03595	COG0673	inositol 2-dehydrogenase activity
EKN16_RS03605	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EKN16_RS03610	COG0789	Transcriptional regulator
EKN16_RS03620	COG0833	amino acid
EKN16_RS03655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS03690	COG1522	sequence-specific DNA binding
EKN16_RS03705	COG4209	transmembrane transport
EKN16_RS03710	COG0395	ABC-type sugar transport system, permease component
EKN16_RS03720	COG1653	transport
EKN16_RS03725	COG2207	Transcriptional regulator
EKN16_RS03740	COG0667	Aldo Keto reductase
EKN16_RS03750	COG2972	Histidine kinase
EKN16_RS03755	COG2207	Transcriptional regulator
EKN16_RS03755	COG4753	response regulator
EKN16_RS03760	COG4209	transmembrane transport
EKN16_RS03765	COG0395	ABC-type sugar transport system, permease component
EKN16_RS03805	COG1737	Transcriptional regulator
EKN16_RS03855	COG0395	ABC-type sugar transport system, permease component
EKN16_RS03870	COG1175	transmembrane transport
EKN16_RS03875	COG3833	ABC-type maltose transport systems, permease component
EKN16_RS03890	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EKN16_RS03900	COG1174	glycine betaine transport
EKN16_RS03905	COG1732	Glycine betaine
EKN16_RS03910	COG1174	glycine betaine transport
EKN16_RS03915	COG1125	glycine betaine transport
EKN16_RS03915	COG0517	IMP dehydrogenase activity
EKN16_RS03920	COG2861	carbohydrate metabolic process
EKN16_RS03925	COG0860	N-Acetylmuramoyl-L-alanine amidase
EKN16_RS03945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EKN16_RS04010	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS04030	COG4977	sequence-specific DNA binding
EKN16_RS04040	COG4209	transmembrane transport
EKN16_RS04045	COG0395	ABC-type sugar transport system, permease component
EKN16_RS04055	COG0673	inositol 2-dehydrogenase activity
EKN16_RS04065	COG3507	Belongs to the glycosyl hydrolase 43 family
EKN16_RS04070	COG3618	amidohydrolase
EKN16_RS04105	COG1349	DNA-binding transcription factor activity
EKN16_RS04135	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EKN16_RS04140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKN16_RS04150	COG2323	membrane
EKN16_RS04170	COG1175	transmembrane transport
EKN16_RS04175	COG0395	ABC-type sugar transport system, permease component
EKN16_RS04185	COG0673	inositol 2-dehydrogenase activity
EKN16_RS04190	COG0456	acetyltransferase
EKN16_RS04200	COG0656	L-ascorbic acid biosynthetic process
EKN16_RS04205	COG2207	Transcriptional regulator
EKN16_RS04215	COG0768	penicillin binding
EKN16_RS04220	COG0772	Belongs to the SEDS family
EKN16_RS04225	COG2706	6-phosphogluconolactonase activity
EKN16_RS04230	COG2140	Oxalate decarboxylase
EKN16_RS04245	COG0673	inositol 2-dehydrogenase activity
EKN16_RS04275	COG2721	sulfolactate sulfo-lyase activity
EKN16_RS04280	COG2721	sulfolactate sulfo-lyase activity
EKN16_RS04285	COG0583	DNA-binding transcription factor activity
EKN16_RS04290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EKN16_RS04305	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS04320	COG1842	Phage shock protein A
EKN16_RS04355	COG1418	mRNA catabolic process
EKN16_RS04370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKN16_RS04390	COG4464	protein tyrosine phosphatase activity
EKN16_RS04395	COG3944	biosynthesis protein
EKN16_RS04400	COG0489	protein tyrosine kinase activity
EKN16_RS04405	COG1086	Polysaccharide biosynthesis protein
EKN16_RS04415	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS04430	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS04430	COG0297	glycogen (starch) synthase activity
EKN16_RS04440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EKN16_RS04450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EKN16_RS04455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EKN16_RS04460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKN16_RS04480	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS04480	COG2207	Transcriptional regulator
EKN16_RS04485	COG1979	alcohol dehydrogenase
EKN16_RS04490	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EKN16_RS04500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EKN16_RS04505	COG0297	glycogen (starch) synthase activity
EKN16_RS04585	COG1070	Carbohydrate kinase
EKN16_RS04590	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EKN16_RS04600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EKN16_RS04605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EKN16_RS04610	COG1832	CoA-binding protein
EKN16_RS04620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKN16_RS04620	COG1263	PTS System
EKN16_RS04620	COG2190	(PTS) system
EKN16_RS04625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKN16_RS04630	COG0693	protein deglycase activity
EKN16_RS04645	COG3118	belongs to the thioredoxin family
EKN16_RS04655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EKN16_RS04660	COG0123	including yeast histone deacetylase and acetoin utilization protein
EKN16_RS04665	COG0454	-acetyltransferase
EKN16_RS04670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EKN16_RS04675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKN16_RS04680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EKN16_RS04685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EKN16_RS04690	COG2199	diguanylate cyclase activity
EKN16_RS04690	COG2203	Gaf domain
EKN16_RS04710	COG4838	Belongs to the UPF0358 family
EKN16_RS04715	COG0387	Pfam Sodium calcium exchanger
EKN16_RS04720	COG1302	Protein conserved in bacteria
EKN16_RS04725	COG0772	Belongs to the SEDS family
EKN16_RS04735	COG1473	amidohydrolase
EKN16_RS04740	COG1061	Type III restriction enzyme res subunit
EKN16_RS04775	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EKN16_RS04780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EKN16_RS04790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EKN16_RS04795	COG0646	methionine synthase
EKN16_RS04795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EKN16_RS04800	COG2052	Domain of unknown function (DUF370)
EKN16_RS04805	COG0194	GDP metabolic process
EKN16_RS04810	COG1758	RNA polymerase activity
EKN16_RS04815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EKN16_RS04820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKN16_RS04825	COG0242	peptide deformylase activity
EKN16_RS04830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EKN16_RS04835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EKN16_RS04835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKN16_RS04840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EKN16_RS04845	COG0631	protein serine/threonine phosphatase activity
EKN16_RS04850	COG2815	serine threonine protein kinase
EKN16_RS04850	COG0515	serine threonine protein kinase
EKN16_RS04860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EKN16_RS04875	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EKN16_RS04880	COG1302	Protein conserved in bacteria
EKN16_RS04885	COG1461	Dihydroxyacetone kinase
EKN16_RS04890	COG1307	EDD domain protein, DegV family
EKN16_RS04895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EKN16_RS04905	COG2135	peptidase activity
EKN16_RS04915	COG0235	Class ii aldolase
EKN16_RS04920	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EKN16_RS04925	COG1850	ribulose-bisphosphate carboxylase activity
EKN16_RS04930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKN16_RS04935	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EKN16_RS04940	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKN16_RS04945	COG0436	Aminotransferase
EKN16_RS04955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKN16_RS04960	COG0583	DNA-binding transcription factor activity
EKN16_RS04965	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EKN16_RS04970	COG0066	3-isopropylmalate dehydratase activity
EKN16_RS04975	COG0860	N-Acetylmuramoyl-L-alanine amidase
EKN16_RS04980	COG0860	N-Acetylmuramoyl-L-alanine amidase
EKN16_RS04995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EKN16_RS05005	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EKN16_RS05010	COG1132	(ABC) transporter
EKN16_RS05015	COG1132	(ABC) transporter
EKN16_RS05020	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EKN16_RS05030	COG1131	(ABC) transporter
EKN16_RS05035	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EKN16_RS05045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKN16_RS05050	COG1846	Transcriptional regulator
EKN16_RS05060	COG0564	pseudouridine synthase activity
EKN16_RS05065	COG0116	Belongs to the methyltransferase superfamily
EKN16_RS05065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EKN16_RS05070	COG0745	RESPONSE REGULATOR receiver
EKN16_RS05075	COG5002	protein histidine kinase activity
EKN16_RS05080	COG3620	sequence-specific DNA binding
EKN16_RS05085	COG2160	L-arabinose isomerase activity
EKN16_RS05090	COG1657	PFAM Prenyltransferase squalene oxidase
EKN16_RS05105	COG2271	Major facilitator Superfamily
EKN16_RS05140	COG1175	transmembrane transport
EKN16_RS05145	COG0395	ABC-type sugar transport system, permease component
EKN16_RS05160	COG0784	Response regulator, receiver
EKN16_RS05165	COG4191	Histidine kinase
EKN16_RS05175	COG1027	Aspartate ammonia-lyase
EKN16_RS05190	COG1309	transcriptional regulator
EKN16_RS05205	COG0402	S-adenosylhomocysteine deaminase activity
EKN16_RS05215	COG1653	transport
EKN16_RS05225	COG0395	ABC-type sugar transport system, permease component
EKN16_RS05230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EKN16_RS05235	COG0006	proline dipeptidase activity
EKN16_RS05255	COG1653	transport
EKN16_RS05260	COG2972	Histidine kinase
EKN16_RS05295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKN16_RS05310	COG2972	Histidine kinase
EKN16_RS05315	COG4753	response regulator
EKN16_RS05315	COG2207	Transcriptional regulator
EKN16_RS05325	COG4209	transmembrane transport
EKN16_RS05330	COG0395	ABC-type sugar transport system, permease component
EKN16_RS05335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKN16_RS05390	COG1547	Domain of unknown function (DUF309)
EKN16_RS05395	COG0288	reversible hydration of carbon dioxide
EKN16_RS05400	COG4918	Iron-sulphur cluster biosynthesis
EKN16_RS05405	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EKN16_RS05415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EKN16_RS05420	COG4129	membrane
EKN16_RS05445	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EKN16_RS05450	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EKN16_RS05455	COG2521	methyltransferase
EKN16_RS05455	COG2136	Putative SAM-dependent methyltransferase
EKN16_RS05460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EKN16_RS05465	COG1923	regulation of RNA biosynthetic process
EKN16_RS05470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKN16_RS05495	COG0464	growth
EKN16_RS05500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EKN16_RS05505	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EKN16_RS05510	COG0789	Transcriptional regulator
EKN16_RS05515	COG0174	glutamine synthetase
EKN16_RS05520	COG4974	Belongs to the 'phage' integrase family
EKN16_RS05650	COG1783	phage Terminase large subunit
EKN16_RS05750	COG3299	homolog of phage Mu protein gp47
EKN16_RS05780	COG4824	toxin secretion phage lysis holin
EKN16_RS05825	COG1396	sequence-specific DNA binding
EKN16_RS05900	COG3299	homolog of phage Mu protein gp47
EKN16_RS05950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EKN16_RS05960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EKN16_RS05970	COG4224	UPF0291 protein
EKN16_RS05975	COG0667	Aldo Keto reductase
EKN16_RS05985	COG1011	Hydrolase
EKN16_RS05990	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EKN16_RS05995	COG0646	methionine synthase
EKN16_RS05995	COG1410	methionine synthase
EKN16_RS06000	COG1234	tRNA 3'-trailer cleavage
EKN16_RS06005	COG1988	membrane-bound metal-dependent
EKN16_RS06010	COG1111	helicase
EKN16_RS06010	COG1205	dead DEAH box helicase
EKN16_RS06020	COG0673	inositol 2-dehydrogenase activity
EKN16_RS06030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EKN16_RS06035	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EKN16_RS06045	COG1119	ATPase activity
EKN16_RS06050	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EKN16_RS06055	COG0515	serine threonine protein kinase
EKN16_RS06060	COG0488	(ABC) transporter
EKN16_RS06070	COG0745	RESPONSE REGULATOR receiver
EKN16_RS06075	COG3850	Histidine kinase
EKN16_RS06075	COG5002	protein histidine kinase activity
EKN16_RS06080	COG3153	acetyltransferase
EKN16_RS06080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKN16_RS06085	COG0456	acetyltransferase
EKN16_RS06095	COG0321	lipoyl(octanoyl) transferase activity
EKN16_RS06095	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EKN16_RS06105	COG2860	membrane
EKN16_RS06110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKN16_RS06140	COG1607	acyl-coa hydrolase
EKN16_RS06150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EKN16_RS06155	COG0493	'glutamate synthase
EKN16_RS06185	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EKN16_RS06200	COG2204	response regulator
EKN16_RS06210	COG2258	MOSC domain
EKN16_RS06230	COG0674	pyruvate-flavodoxin oxidoreductase activity
EKN16_RS06245	COG0492	ferredoxin-NADP+ reductase activity
EKN16_RS06255	COG1132	(ABC) transporter
EKN16_RS06260	COG1132	(ABC) transporter
EKN16_RS06270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EKN16_RS06275	COG0714	Associated with various cellular activities
EKN16_RS06320	COG2217	Heavy metal translocating P-type atpase
EKN16_RS06325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS06330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKN16_RS06335	COG1120	ATPase activity
EKN16_RS06340	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EKN16_RS06345	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
EKN16_RS06355	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EKN16_RS06360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKN16_RS06365	COG1492	cobalamin metabolic process
EKN16_RS06375	COG1643	Atp-dependent helicase
EKN16_RS06385	COG3973	AAA domain
EKN16_RS06420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKN16_RS06425	COG0384	phenazine biosynthesis protein PhzF
EKN16_RS06430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKN16_RS06440	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS06445	COG0745	RESPONSE REGULATOR receiver
EKN16_RS06450	COG5002	protein histidine kinase activity
EKN16_RS06460	COG0667	Aldo Keto reductase
EKN16_RS06475	COG0714	Associated with various cellular activities
EKN16_RS06485	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EKN16_RS06490	COG3973	AAA domain
EKN16_RS06500	COG0702	epimerase
EKN16_RS06525	COG1435	thymidine kinase activity
EKN16_RS06530	COG2390	Transcriptional regulator
EKN16_RS06535	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EKN16_RS06540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKN16_RS06545	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EKN16_RS06555	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EKN16_RS06560	COG2323	membrane
EKN16_RS06570	COG0488	(ABC) transporter
EKN16_RS06580	COG0583	DNA-binding transcription factor activity
EKN16_RS06585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKN16_RS06590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EKN16_RS06600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKN16_RS06620	COG1760	l-serine dehydratase
EKN16_RS06625	COG1760	l-serine dehydratase
EKN16_RS06630	COG1368	sulfuric ester hydrolase activity
EKN16_RS06640	COG1695	Transcriptional regulator
EKN16_RS06645	COG0772	Belongs to the SEDS family
EKN16_RS06665	COG3226	Transcriptional regulator
EKN16_RS06685	COG0601	transmembrane transport
EKN16_RS06690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKN16_RS06695	COG0444	Belongs to the ABC transporter superfamily
EKN16_RS06700	COG4608	Belongs to the ABC transporter superfamily
EKN16_RS06720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EKN16_RS06730	COG1959	2 iron, 2 sulfur cluster binding
EKN16_RS06745	COG2186	Transcriptional regulator
EKN16_RS06750	COG2807	transmembrane transport
EKN16_RS06780	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EKN16_RS06795	COG1175	transmembrane transport
EKN16_RS06800	COG0395	ABC-type sugar transport system, permease component
EKN16_RS06815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EKN16_RS06825	COG0189	ligase activity
EKN16_RS06865	COG4974	Belongs to the 'phage' integrase family
EKN16_RS06880	COG1012	belongs to the aldehyde dehydrogenase family
EKN16_RS06890	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EKN16_RS06900	COG1054	Belongs to the UPF0176 family
EKN16_RS06905	COG0753	catalase activity
EKN16_RS06920	COG0583	DNA-binding transcription factor activity
EKN16_RS06925	COG0666	response to abiotic stimulus
EKN16_RS06930	COG0402	S-adenosylhomocysteine deaminase activity
EKN16_RS06935	COG1742	UPF0060 membrane protein
EKN16_RS06965	COG1309	transcriptional regulator
EKN16_RS06970	COG2124	cytochrome p450
EKN16_RS07005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKN16_RS07010	COG1349	DNA-binding transcription factor activity
EKN16_RS07020	COG1357	PFAM Pentapeptide repeats (8 copies)
EKN16_RS07040	COG0745	RESPONSE REGULATOR receiver
EKN16_RS07045	COG5002	protein histidine kinase activity
EKN16_RS07090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EKN16_RS07100	COG0672	)-iron permease
EKN16_RS07105	COG5001	Diguanylate cyclase
EKN16_RS07105	COG3300	MHYT domain
EKN16_RS07125	COG0517	IMP dehydrogenase activity
EKN16_RS07130	COG0367	asparagine synthase
EKN16_RS07140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKN16_RS07160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EKN16_RS07165	COG4977	sequence-specific DNA binding
EKN16_RS07165	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS07190	COG4209	transmembrane transport
EKN16_RS07195	COG0395	ABC-type sugar transport system, permease component
EKN16_RS07200	COG1653	transport
EKN16_RS07205	COG5652	VanZ like family
EKN16_RS07210	COG4977	sequence-specific DNA binding
EKN16_RS07240	COG0659	secondary active sulfate transmembrane transporter activity
EKN16_RS07275	COG0697	spore germination
EKN16_RS07285	COG0745	RESPONSE REGULATOR receiver
EKN16_RS07290	COG2205	protein histidine kinase activity
EKN16_RS07295	COG1136	(ABC) transporter
EKN16_RS07300	COG0577	efflux transmembrane transporter activity
EKN16_RS07305	COG1193	negative regulation of DNA recombination
EKN16_RS07310	COG1216	Glycosyl transferase, family 2
EKN16_RS07310	COG0463	Glycosyl transferase, family 2
EKN16_RS07365	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EKN16_RS07380	COG1388	LysM domain
EKN16_RS07390	COG5146	pantothenate kinase activity
EKN16_RS07400	COG0840	transmembrane signaling receptor activity
EKN16_RS07410	COG0579	oxidoreductase
EKN16_RS07440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EKN16_RS07460	COG0477	Major facilitator Superfamily
EKN16_RS07470	COG0789	Transcriptional regulator
EKN16_RS07475	COG0477	Major facilitator Superfamily
EKN16_RS07480	COG0583	DNA-binding transcription factor activity
EKN16_RS07495	COG0456	acetyltransferase
EKN16_RS07495	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EKN16_RS07535	COG3119	arylsulfatase activity
EKN16_RS07540	COG3345	alpha-galactosidase
EKN16_RS07555	COG0583	DNA-binding transcription factor activity
EKN16_RS07560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EKN16_RS07575	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EKN16_RS07590	COG2814	Major facilitator Superfamily
EKN16_RS07595	COG2207	Transcriptional regulator
EKN16_RS07600	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS07605	COG1902	pentaerythritol trinitrate reductase activity
EKN16_RS07615	COG4221	oxidoreductase activity
EKN16_RS07630	COG0745	RESPONSE REGULATOR receiver
EKN16_RS07635	COG5002	protein histidine kinase activity
EKN16_RS07635	COG3850	Histidine kinase
EKN16_RS07640	COG1063	alcohol dehydrogenase
EKN16_RS07660	COG0640	Transcriptional regulator
EKN16_RS07680	COG3708	Transcriptional regulator
EKN16_RS07680	COG2207	Transcriptional regulator
EKN16_RS07705	COG0789	Transcriptional regulator
EKN16_RS07740	COG0129	dihydroxy-acid dehydratase activity
EKN16_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS07750	COG1653	transport
EKN16_RS07755	COG1175	transmembrane transport
EKN16_RS07760	COG0395	ABC-type sugar transport system, permease component
EKN16_RS07860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EKN16_RS07885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EKN16_RS07900	COG0519	Catalyzes the synthesis of GMP from XMP
EKN16_RS07905	COG2116	formate transmembrane transporter activity
EKN16_RS07910	COG2146	nitrite reductase [NAD(P)H] activity
EKN16_RS07915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKN16_RS07930	COG1653	transport
EKN16_RS07935	COG0395	ABC-type sugar transport system, permease component
EKN16_RS07940	COG4209	transmembrane transport
EKN16_RS07945	COG2207	Transcriptional regulator
EKN16_RS07960	COG5002	protein histidine kinase activity
EKN16_RS07970	COG0330	HflC and HflK could
EKN16_RS07980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKN16_RS07980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKN16_RS08030	COG0442	prolyl-tRNA aminoacylation
EKN16_RS08035	COG2814	Major facilitator Superfamily
EKN16_RS08040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EKN16_RS08050	COG0673	inositol 2-dehydrogenase activity
EKN16_RS08055	COG0386	Belongs to the glutathione peroxidase family
EKN16_RS08080	COG3708	Transcriptional regulator
EKN16_RS08080	COG2207	Transcriptional regulator
EKN16_RS08090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKN16_RS08095	COG4948	Mandelate Racemase Muconate Lactonizing
EKN16_RS08100	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS08105	COG4948	Mandelate Racemase Muconate Lactonizing
EKN16_RS08110	COG0395	ABC-type sugar transport system, permease component
EKN16_RS08130	COG0395	ABC-type sugar transport system, permease component
EKN16_RS08135	COG1175	transmembrane transport
EKN16_RS08145	COG3842	ATPase activity
EKN16_RS08150	COG1653	transport
EKN16_RS08155	COG1609	Transcriptional regulator
EKN16_RS08165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EKN16_RS08195	COG0745	RESPONSE REGULATOR receiver
EKN16_RS08200	COG1999	signal sequence binding
EKN16_RS08220	COG2911	Protein conserved in bacteria
EKN16_RS08220	COG1361	Conserved repeat domain
EKN16_RS08220	COG3266	domain, Protein
EKN16_RS08225	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EKN16_RS08230	COG1472	Belongs to the glycosyl hydrolase 3 family
EKN16_RS08235	COG2207	Transcriptional regulator
EKN16_RS08240	COG2972	Histidine kinase
EKN16_RS08245	COG0395	ABC-type sugar transport system, permease component
EKN16_RS08250	COG1175	transmembrane transport
EKN16_RS08260	COG0673	inositol 2-dehydrogenase activity
EKN16_RS08280	COG0697	spore germination
EKN16_RS08295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKN16_RS08300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EKN16_RS08310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKN16_RS08315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EKN16_RS08325	COG0640	Transcriptional regulator
EKN16_RS08330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EKN16_RS08335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKN16_RS08350	COG1376	ErfK ybiS ycfS ynhG family protein
EKN16_RS08395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKN16_RS08420	COG1595	DNA-templated transcription, initiation
EKN16_RS08425	COG0586	Pfam SNARE associated Golgi protein
EKN16_RS08430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EKN16_RS08435	COG0392	lysyltransferase activity
EKN16_RS08435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKN16_RS08445	COG0492	ferredoxin-NADP+ reductase activity
EKN16_RS08450	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EKN16_RS08460	COG0110	maltose O-acetyltransferase activity
EKN16_RS08470	COG2814	Major facilitator Superfamily
EKN16_RS08475	COG2378	regulation of single-species biofilm formation
EKN16_RS08480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKN16_RS08500	COG0840	transmembrane signaling receptor activity
EKN16_RS08510	COG1695	Transcriptional regulator
EKN16_RS08515	COG1132	(ABC) transporter
EKN16_RS08540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKN16_RS08555	COG0395	ABC-type sugar transport system, permease component
EKN16_RS08560	COG4209	transmembrane transport
EKN16_RS08565	COG0383	alpha-mannosidase activity
EKN16_RS08590	COG3773	Cell wall hydrolase
EKN16_RS08605	COG0456	acetyltransferase
EKN16_RS08605	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EKN16_RS08645	COG4974	Belongs to the 'phage' integrase family
EKN16_RS08650	COG0517	IMP dehydrogenase activity
EKN16_RS08665	COG0494	nUDIX hydrolase
EKN16_RS08725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EKN16_RS08820	COG4974	Belongs to the 'phage' integrase family
EKN16_RS08830	COG0706	membrane insertase activity
EKN16_RS08850	COG0436	Aminotransferase
EKN16_RS08860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKN16_RS08870	COG0697	spore germination
EKN16_RS08875	COG5263	repeat protein
EKN16_RS08875	COG4193	domain, Protein
EKN16_RS08890	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EKN16_RS08945	COG0778	Nitroreductase
EKN16_RS08975	COG0488	(ABC) transporter
EKN16_RS08980	COG0254	rRNA binding
EKN16_RS08985	COG0583	DNA-binding transcription factor activity
EKN16_RS08990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EKN16_RS09005	COG0697	spore germination
EKN16_RS09010	COG0583	DNA-binding transcription factor activity
EKN16_RS09020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKN16_RS09020	COG3153	acetyltransferase
EKN16_RS09025	COG3153	acetyltransferase
EKN16_RS09025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKN16_RS09075	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EKN16_RS09085	COG1653	transport
EKN16_RS09090	COG0395	ABC-type sugar transport system, permease component
EKN16_RS09095	COG4209	transmembrane transport
EKN16_RS09100	COG2972	Histidine kinase
EKN16_RS09105	COG2207	Transcriptional regulator
EKN16_RS09105	COG4753	response regulator
EKN16_RS09120	COG0791	NLP P60 protein
EKN16_RS09140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EKN16_RS09140	COG0723	plastoquinol--plastocyanin reductase activity
EKN16_RS09145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EKN16_RS09165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKN16_RS09185	COG0366	Alpha amylase catalytic
EKN16_RS09190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS09205	COG0395	ABC-type sugar transport system, permease component
EKN16_RS09210	COG4209	transmembrane transport
EKN16_RS09215	COG1653	transport
EKN16_RS09225	COG3275	phosphorelay sensor kinase activity
EKN16_RS09230	COG1649	PFAM Uncharacterised BCR, COG1649
EKN16_RS09240	COG3119	arylsulfatase activity
EKN16_RS09245	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS09245	COG2207	Transcriptional regulator
EKN16_RS09250	COG3119	arylsulfatase activity
EKN16_RS09255	COG0529	Catalyzes the synthesis of activated sulfate
EKN16_RS09260	COG0673	inositol 2-dehydrogenase activity
EKN16_RS09265	COG3119	arylsulfatase activity
EKN16_RS09290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EKN16_RS09295	COG2207	Transcriptional regulator
EKN16_RS09305	COG0673	inositol 2-dehydrogenase activity
EKN16_RS09310	COG1486	melibiose metabolic process
EKN16_RS09315	COG1802	Transcriptional regulator
EKN16_RS09330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EKN16_RS09335	COG0523	cobalamin synthesis protein
EKN16_RS09340	COG0803	Belongs to the bacterial solute-binding protein 9 family
EKN16_RS09345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EKN16_RS09350	COG1121	(ABC) transporter
EKN16_RS09355	COG0523	cobalamin synthesis protein
EKN16_RS09365	COG0701	Predicted permease
EKN16_RS09375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EKN16_RS09385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKN16_RS09430	COG1595	DNA-templated transcription, initiation
EKN16_RS09460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKN16_RS09480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EKN16_RS09495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKN16_RS09520	COG1959	2 iron, 2 sulfur cluster binding
EKN16_RS09545	COG0653	protein targeting
EKN16_RS09575	COG0640	Transcriptional regulator
EKN16_RS09585	COG4948	Mandelate Racemase Muconate Lactonizing
EKN16_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS09615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EKN16_RS09620	COG2972	Histidine kinase
EKN16_RS09625	COG3279	Response regulator of the LytR AlgR family
EKN16_RS09645	COG1752	Esterase of the alpha-beta hydrolase superfamily
EKN16_RS09655	COG0840	transmembrane signaling receptor activity
EKN16_RS09665	COG0454	-acetyltransferase
EKN16_RS09685	COG1175	transmembrane transport
EKN16_RS09700	COG0395	ABC-type sugar transport system, permease component
EKN16_RS09720	COG1609	Transcriptional regulator
EKN16_RS09750	COG3011	Protein conserved in bacteria
EKN16_RS09760	COG0784	Response regulator, receiver
EKN16_RS09760	COG4191	Histidine kinase
EKN16_RS09795	COG0697	spore germination
EKN16_RS09805	COG1619	proteins homologs of microcin C7 resistance protein MccF
EKN16_RS09815	COG0366	Alpha amylase catalytic
EKN16_RS09820	COG0395	ABC-type sugar transport system, permease component
EKN16_RS09825	COG1175	transmembrane transport
EKN16_RS09835	COG2207	Transcriptional regulator
EKN16_RS09840	COG2972	Histidine kinase
EKN16_RS09865	COG2207	Transcriptional regulator
EKN16_RS09865	COG4753	response regulator
EKN16_RS09870	COG2972	Histidine kinase
EKN16_RS09880	COG1472	Belongs to the glycosyl hydrolase 3 family
EKN16_RS09885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS09885	COG2207	Transcriptional regulator
EKN16_RS09890	COG0596	Alpha beta hydrolase
EKN16_RS09920	COG1902	pentaerythritol trinitrate reductase activity
EKN16_RS09935	COG1181	Belongs to the D-alanine--D-alanine ligase family
EKN16_RS09945	COG2814	Major facilitator Superfamily
EKN16_RS09980	COG3850	Histidine kinase
EKN16_RS09980	COG5002	protein histidine kinase activity
EKN16_RS09985	COG0745	RESPONSE REGULATOR receiver
EKN16_RS09995	COG0390	transport system, permease component
EKN16_RS10000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EKN16_RS10005	COG0745	RESPONSE REGULATOR receiver
EKN16_RS10010	COG5002	protein histidine kinase activity
EKN16_RS10020	COG1131	(ABC) transporter
EKN16_RS10030	COG3511	phospholipase C
EKN16_RS10065	COG0159	tryptophan synthase activity
EKN16_RS10070	COG0133	tryptophan synthase activity
EKN16_RS10100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKN16_RS10105	COG0805	protein transport
EKN16_RS10120	COG1063	alcohol dehydrogenase
EKN16_RS10125	COG2207	Transcriptional regulator
EKN16_RS10130	COG1363	Peptidase, m42
EKN16_RS10140	COG0531	amino acid
EKN16_RS10150	COG1122	ATPase activity
EKN16_RS10155	COG1268	BioY protein
EKN16_RS10165	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EKN16_RS10170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EKN16_RS10175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EKN16_RS10190	COG0463	Glycosyl transferase, family 2
EKN16_RS10195	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKN16_RS10200	COG0745	RESPONSE REGULATOR receiver
EKN16_RS10205	COG3850	Histidine kinase
EKN16_RS10205	COG5002	protein histidine kinase activity
EKN16_RS10210	COG0726	polysaccharide deacetylase
EKN16_RS10220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EKN16_RS10240	COG1607	acyl-coa hydrolase
EKN16_RS10250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EKN16_RS10255	COG5002	protein histidine kinase activity
EKN16_RS10260	COG0745	RESPONSE REGULATOR receiver
EKN16_RS10280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EKN16_RS10285	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKN16_RS10290	COG0567	Dehydrogenase, E1 component
EKN16_RS10295	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EKN16_RS10305	COG1199	ATP-dependent helicase activity
EKN16_RS10310	COG2608	mercury ion transmembrane transporter activity
EKN16_RS10315	COG2217	Heavy metal translocating P-type atpase
EKN16_RS10335	COG5002	protein histidine kinase activity
EKN16_RS10340	COG0745	RESPONSE REGULATOR receiver
EKN16_RS10345	COG0038	chloride channel
EKN16_RS10355	COG1686	Belongs to the peptidase S11 family
EKN16_RS10360	COG5002	protein histidine kinase activity
EKN16_RS10370	COG1132	(ABC) transporter
EKN16_RS10380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EKN16_RS10400	COG2814	Major facilitator Superfamily
EKN16_RS10405	COG4550	Control of competence regulator ComK, YlbF/YmcA
EKN16_RS10410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKN16_RS10415	COG4869	propanediol catabolic process
EKN16_RS10420	COG1013	pyruvate-flavodoxin oxidoreductase activity
EKN16_RS10425	COG0674	pyruvate-flavodoxin oxidoreductase activity
EKN16_RS10425	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EKN16_RS10435	COG2359	stage V sporulation protein S
EKN16_RS10440	COG1692	metallophosphoesterase
EKN16_RS10445	COG1418	mRNA catabolic process
EKN16_RS10450	COG2137	regulation of response to DNA damage stimulus
EKN16_RS10455	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EKN16_RS10460	COG1546	Belongs to the CinA family
EKN16_RS10460	COG1058	Belongs to the CinA family
EKN16_RS10465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKN16_RS10470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKN16_RS10480	COG1426	Protein conserved in bacteria
EKN16_RS10495	COG0300	oxidoreductase activity
EKN16_RS10500	COG0612	Peptidase, M16
EKN16_RS10505	COG0612	Peptidase, M16
EKN16_RS10515	COG1674	ftsk spoiiie
EKN16_RS10525	COG0740	serine-type endopeptidase activity
EKN16_RS10530	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKN16_RS10540	COG0527	aspartate kinase activity
EKN16_RS10545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EKN16_RS10550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EKN16_RS10555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKN16_RS10560	COG0756	dUTP diphosphatase activity
EKN16_RS10565	COG0612	Peptidase, M16
EKN16_RS10570	COG0726	polysaccharide deacetylase
EKN16_RS10575	COG1185	polyribonucleotide nucleotidyltransferase activity
EKN16_RS10580	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EKN16_RS10585	COG0196	riboflavin kinase activity
EKN16_RS10590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EKN16_RS10595	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EKN16_RS10600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EKN16_RS10615	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EKN16_RS10620	COG0195	Participates in both transcription termination and antitermination
EKN16_RS10625	COG0779	Required for maturation of 30S ribosomal subunits
EKN16_RS10630	COG2176	DNA-directed DNA polymerase activity
EKN16_RS10635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKN16_RS10640	COG0750	zinc metalloprotease
EKN16_RS10645	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EKN16_RS10650	COG4589	Belongs to the CDS family
EKN16_RS10655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKN16_RS10660	COG0233	cytoplasmic translational termination
EKN16_RS10665	COG0528	UMP kinase activity
EKN16_RS10670	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EKN16_RS10675	COG0052	Belongs to the universal ribosomal protein uS2 family
EKN16_RS10700	COG1191	sigma factor activity
EKN16_RS10710	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EKN16_RS10715	COG1776	CheC inhibitor of MCP methylation
EKN16_RS10720	COG0835	chemotaxis
EKN16_RS10725	COG2198	Histidine kinase
EKN16_RS10725	COG0643	Histidine kinase
EKN16_RS10730	COG2201	protein-glutamate methylesterase activity
EKN16_RS10735	COG0455	bacterial-type flagellum organization
EKN16_RS10740	COG1419	protein localization to endoplasmic reticulum
EKN16_RS10745	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EKN16_RS10750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EKN16_RS10755	COG1684	flagellar biosynthetic protein fliR
EKN16_RS10760	COG1987	bacterial-type flagellum assembly
EKN16_RS10765	COG1338	Plays a role in the flagellum-specific transport system
EKN16_RS10775	COG2201	protein-glutamate methylesterase activity
EKN16_RS10780	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EKN16_RS10780	COG1776	CheC inhibitor of MCP methylation
EKN16_RS10785	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EKN16_RS10800	COG4786	Flagellar basal body rod
EKN16_RS10810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EKN16_RS10830	COG1157	protein secretion by the type III secretion system
EKN16_RS10840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EKN16_RS10845	COG1766	The M ring may be actively involved in energy transduction
EKN16_RS10850	COG1677	Flagellar hook-basal body complex protein FliE
EKN16_RS10855	COG1558	bacterial-type flagellum-dependent cell motility
EKN16_RS10860	COG1815	bacterial-type flagellum-dependent cell motility
EKN16_RS10865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EKN16_RS10870	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EKN16_RS10875	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EKN16_RS10880	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EKN16_RS10885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKN16_RS10890	COG0758	DNA mediated transformation
EKN16_RS10895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EKN16_RS10900	COG0045	succinate-CoA ligase (ADP-forming) activity
EKN16_RS10910	COG0606	chelatase, subunit chli
EKN16_RS10915	COG0792	nuclease activity
EKN16_RS10920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EKN16_RS10930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKN16_RS10945	COG0335	large ribosomal subunit rRNA binding
EKN16_RS10965	COG0228	four-way junction DNA binding
EKN16_RS10970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EKN16_RS10975	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EKN16_RS10980	COG0552	protein localization to endoplasmic reticulum
EKN16_RS10985	COG1196	nuclear chromosome segregation
EKN16_RS10995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EKN16_RS11000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKN16_RS11005	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS11010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EKN16_RS11020	COG0416	fatty acid biosynthetic process
EKN16_RS11025	COG2050	protein possibly involved in aromatic compounds catabolism
EKN16_RS11025	COG1349	DNA-binding transcription factor activity
EKN16_RS11030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EKN16_RS11040	COG1323	Belongs to the UPF0348 family
EKN16_RS11045	COG3314	Sporulation integral membrane protein YlbJ
EKN16_RS11050	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EKN16_RS11055	COG0742	ribosomal rna small subunit methyltransferase
EKN16_RS11065	COG4608	Belongs to the ABC transporter superfamily
EKN16_RS11070	COG0444	Belongs to the ABC transporter superfamily
EKN16_RS11075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKN16_RS11080	COG0601	transmembrane transport
EKN16_RS11085	COG4166	transmembrane transport
EKN16_RS11090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EKN16_RS11095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKN16_RS11105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EKN16_RS11110	COG0586	Pfam SNARE associated Golgi protein
EKN16_RS11125	COG3069	C4-dicarboxylate transmembrane transporter activity
EKN16_RS11135	COG0084	hydrolase, TatD family'
EKN16_RS11140	COG1116	anion transmembrane transporter activity
EKN16_RS11145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EKN16_RS11150	COG0011	TIGRFAM Protein of
EKN16_RS11155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EKN16_RS11165	COG2226	methyltransferase
EKN16_RS11170	COG3935	DnaD domain protein
EKN16_RS11175	COG0017	Asparaginyl-tRNA synthetase
EKN16_RS11180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EKN16_RS11185	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKN16_RS11190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKN16_RS11205	COG0402	S-adenosylhomocysteine deaminase activity
EKN16_RS11210	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EKN16_RS11215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EKN16_RS11215	COG1199	ATP-dependent helicase activity
EKN16_RS11230	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EKN16_RS11235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EKN16_RS11250	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS11255	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EKN16_RS11260	COG1803	Methylglyoxal synthase
EKN16_RS11265	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EKN16_RS11275	COG1694	Mazg nucleotide pyrophosphohydrolase
EKN16_RS11280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKN16_RS11290	COG4347	Protein of unknown function (DUF1405)
EKN16_RS11295	COG2010	Cytochrome c
EKN16_RS11295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EKN16_RS11300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EKN16_RS11340	COG0287	Prephenate dehydrogenase
EKN16_RS11345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKN16_RS11350	COG0159	tryptophan synthase activity
EKN16_RS11355	COG0133	tryptophan synthase activity
EKN16_RS11360	COG0135	phosphoribosylanthranilate isomerase activity
EKN16_RS11365	COG0134	indole-3-glycerol-phosphate synthase activity
EKN16_RS11370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EKN16_RS11380	COG4401	Chorismate mutase type I
EKN16_RS11385	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EKN16_RS11390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EKN16_RS11395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EKN16_RS11405	COG0142	geranyltranstransferase activity
EKN16_RS11410	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EKN16_RS11415	COG0163	prenyltransferase activity
EKN16_RS11420	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EKN16_RS11445	COG0776	regulation of translation
EKN16_RS11450	COG1172	Belongs to the binding-protein-dependent transport system permease family
EKN16_RS11455	COG1129	ABC transporter
EKN16_RS11465	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EKN16_RS11500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EKN16_RS11505	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EKN16_RS11510	COG1160	GTP binding
EKN16_RS11535	COG0204	Acyl-transferase
EKN16_RS11540	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EKN16_RS11555	COG2959	enzyme of heme biosynthesis
EKN16_RS11560	COG2339	peptidase activity
EKN16_RS11565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EKN16_RS11570	COG4862	establishment of competence for transformation
EKN16_RS11585	COG1408	metallophosphoesterase
EKN16_RS11605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EKN16_RS11610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EKN16_RS11615	COG5002	protein histidine kinase activity
EKN16_RS11615	COG5002	protein histidine kinase activity
EKN16_RS11620	COG0745	RESPONSE REGULATOR receiver
EKN16_RS11625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EKN16_RS11630	COG1333	cytochrome c biogenesis protein
EKN16_RS11635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EKN16_RS11640	COG1187	pseudouridine synthase activity
EKN16_RS11645	COG0700	Nucleoside recognition
EKN16_RS11650	COG2715	membrane protein required for spore maturation
EKN16_RS11655	COG1686	Belongs to the peptidase S11 family
EKN16_RS11660	COG3874	Sporulation protein YtfJ
EKN16_RS11670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EKN16_RS11675	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EKN16_RS11680	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EKN16_RS11685	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EKN16_RS11685	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EKN16_RS11695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EKN16_RS11695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EKN16_RS11705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EKN16_RS11710	COG0019	diaminopimelate decarboxylase activity
EKN16_RS11715	COG0697	spore germination
EKN16_RS11735	COG2172	sigma factor antagonist activity
EKN16_RS11740	COG1366	Belongs to the anti-sigma-factor antagonist family
EKN16_RS11745	COG1686	Belongs to the peptidase S11 family
EKN16_RS11760	COG4974	Belongs to the 'phage' integrase family
EKN16_RS11770	COG0686	Belongs to the AlaDH PNT family
EKN16_RS11780	COG0735	belongs to the Fur family
EKN16_RS11785	COG1300	Membrane
EKN16_RS11790	COG1379	DNA repair
EKN16_RS11805	COG2195	Cleaves the N-terminal amino acid of tripeptides
EKN16_RS11810	COG0321	lipoyl(octanoyl) transferase activity
EKN16_RS11815	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKN16_RS11820	COG0022	dehydrogenase e1 component
EKN16_RS11825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EKN16_RS11830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EKN16_RS11870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EKN16_RS11875	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS11890	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKN16_RS11895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EKN16_RS11905	COG0463	Glycosyl transferase, family 2
EKN16_RS11905	COG0457	Tetratricopeptide repeat
EKN16_RS11910	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS11915	COG0463	Glycosyl transferase, family 2
EKN16_RS11930	COG0745	RESPONSE REGULATOR receiver
EKN16_RS11935	COG0750	zinc metalloprotease
EKN16_RS11940	COG0497	DNA recombination
EKN16_RS11945	COG1438	arginine binding
EKN16_RS11955	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EKN16_RS11960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EKN16_RS11970	COG1722	exodeoxyribonuclease VII activity
EKN16_RS11980	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EKN16_RS11985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKN16_RS12000	COG1302	Protein conserved in bacteria
EKN16_RS12005	COG0439	Biotin carboxylase
EKN16_RS12010	COG0511	ligase activity, forming carbon-carbon bonds
EKN16_RS12050	COG3854	ATPases associated with a variety of cellular activities
EKN16_RS12060	COG1809	phosphosulfolactate synthase activity
EKN16_RS12065	COG2045	Belongs to the ComB family
EKN16_RS12070	COG2707	UPF0756 membrane protein
EKN16_RS12080	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EKN16_RS12085	COG0006	proline dipeptidase activity
EKN16_RS12100	COG3872	metal-dependent enzyme
EKN16_RS12110	COG1321	iron dependent repressor
EKN16_RS12115	COG0785	Cytochrome C biogenesis protein
EKN16_RS12120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EKN16_RS12125	COG1121	(ABC) transporter
EKN16_RS12130	COG3443	Belongs to the bacterial solute-binding protein 9 family
EKN16_RS12130	COG0803	Belongs to the bacterial solute-binding protein 9 family
EKN16_RS12145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EKN16_RS12150	COG0673	inositol 2-dehydrogenase activity
EKN16_RS12160	COG0673	inositol 2-dehydrogenase activity
EKN16_RS12175	COG2197	response regulator
EKN16_RS12180	COG4493	Belongs to the UPF0637 family
EKN16_RS12185	COG2223	nitrite transmembrane transporter activity
EKN16_RS12190	COG2186	Transcriptional regulator
EKN16_RS12195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EKN16_RS12200	COG1131	(ABC) transporter
EKN16_RS12205	COG1511	domain protein
EKN16_RS12205	COG0842	Transport permease protein
EKN16_RS12210	COG1309	transcriptional regulator
EKN16_RS12215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKN16_RS12225	COG1136	(ABC) transporter
EKN16_RS12230	COG2205	protein histidine kinase activity
EKN16_RS12235	COG0745	RESPONSE REGULATOR receiver
EKN16_RS12250	COG1982	Orn Lys Arg decarboxylase major
EKN16_RS12255	COG0412	Dienelactone hydrolase
EKN16_RS12265	COG3906	Belongs to the UPF0473 family
EKN16_RS12280	COG1234	tRNA 3'-trailer cleavage
EKN16_RS12320	COG0667	Aldo Keto reductase
EKN16_RS12325	COG1376	ErfK ybiS ycfS ynhG family protein
EKN16_RS12340	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EKN16_RS12365	COG1136	(ABC) transporter
EKN16_RS12365	COG0577	efflux transmembrane transporter activity
EKN16_RS12380	COG0577	efflux transmembrane transporter activity
EKN16_RS12380	COG1136	(ABC) transporter
EKN16_RS12385	COG0840	transmembrane signaling receptor activity
EKN16_RS12400	COG1131	(ABC) transporter
EKN16_RS12405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EKN16_RS12410	COG0284	orotidine-5'-phosphate decarboxylase activity
EKN16_RS12430	COG0540	Belongs to the ATCase OTCase family
EKN16_RS12435	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EKN16_RS12440	COG0436	Aminotransferase
EKN16_RS12445	COG0564	pseudouridine synthase activity
EKN16_RS12450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EKN16_RS12455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EKN16_RS12475	COG3599	regulation of cell shape
EKN16_RS12480	COG2302	S4 RNA-binding domain
EKN16_RS12485	COG0762	integral membrane protein
EKN16_RS12490	COG1799	cell septum assembly
EKN16_RS12495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EKN16_RS12500	COG1496	oxidoreductase activity
EKN16_RS12505	COG1873	PFAM PRC-barrel domain
EKN16_RS12510	COG1191	sigma factor activity
EKN16_RS12530	COG1725	Transcriptional regulator
EKN16_RS12540	COG2011	ABC-type metal ion transport system permease component
EKN16_RS12545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EKN16_RS12550	COG1191	sigma factor activity
EKN16_RS12560	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EKN16_RS12565	COG0849	cell division
EKN16_RS12570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EKN16_RS12575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKN16_RS12580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EKN16_RS12590	COG0772	Belongs to the SEDS family
EKN16_RS12595	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EKN16_RS12600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKN16_RS12605	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EKN16_RS12615	COG0768	penicillin binding
EKN16_RS12620	COG0768	penicillin binding
EKN16_RS12630	COG0275	rRNA processing
EKN16_RS12635	COG2001	Belongs to the MraZ family
EKN16_RS12655	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EKN16_RS12670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKN16_RS12705	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EKN16_RS12735	COG1217	gtp-binding protein TYPA
EKN16_RS12745	COG0861	Integral membrane protein TerC family
EKN16_RS12750	COG0861	Integral membrane protein TerC family
EKN16_RS12755	COG0301	tRNA thio-modification
EKN16_RS12765	COG0741	lytic transglycosylase activity
EKN16_RS12770	COG4709	membrane
EKN16_RS12795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EKN16_RS12800	COG2384	SAM-dependent methyltransferase
EKN16_RS12815	COG0358	DNA primase activity
EKN16_RS12820	COG1671	Belongs to the UPF0178 family
EKN16_RS12825	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EKN16_RS12830	COG0751	glycine-tRNA ligase activity
EKN16_RS12835	COG0752	glycyl-tRNA synthetase alpha subunit
EKN16_RS12840	COG1381	Involved in DNA repair and RecF pathway recombination
EKN16_RS12850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EKN16_RS12860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EKN16_RS12865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EKN16_RS12870	COG1480	7TM receptor with intracellular HD hydrolase
EKN16_RS12875	COG1702	phosphate starvation-inducible protein PhoH
EKN16_RS12895	COG4864	UPF0365 protein
EKN16_RS12905	COG0534	Mate efflux family protein
EKN16_RS12910	COG1610	YqeY-like protein
EKN16_RS12915	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EKN16_RS12920	COG0537	adenosine 5'-monophosphoramidase activity
EKN16_RS12955	COG0419	ATPase involved in DNA repair
EKN16_RS12960	COG0420	3'-5' exonuclease activity
EKN16_RS12965	COG1074	ATP-dependent DNA helicase activity
EKN16_RS12975	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EKN16_RS12985	COG0673	inositol 2-dehydrogenase activity
EKN16_RS12990	COG1653	transport
EKN16_RS12995	COG0395	ABC-type sugar transport system, permease component
EKN16_RS13000	COG4209	transmembrane transport
EKN16_RS13015	COG2207	Transcriptional regulator
EKN16_RS13030	COG1283	sodium-dependent phosphate transmembrane transporter activity
EKN16_RS13040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKN16_RS13045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EKN16_RS13050	COG1994	Peptidase M50
EKN16_RS13055	COG2264	protein methyltransferase activity
EKN16_RS13075	COG0443	Heat shock 70 kDa protein
EKN16_RS13085	COG1420	regulation of RNA biosynthetic process
EKN16_RS13095	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EKN16_RS13095	COG0165	Argininosuccinate lyase
EKN16_RS13105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EKN16_RS13120	COG0860	N-Acetylmuramoyl-L-alanine amidase
EKN16_RS13125	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EKN16_RS13130	COG0268	Binds directly to 16S ribosomal RNA
EKN16_RS13135	COG1466	dna polymerase III delta subunit
EKN16_RS13145	COG1595	DNA-templated transcription, initiation
EKN16_RS13150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKN16_RS13175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKN16_RS13180	COG0495	leucyl-tRNA aminoacylation
EKN16_RS13185	COG2226	methyltransferase
EKN16_RS13190	COG2996	Protein conserved in bacteria
EKN16_RS13195	COG0799	negative regulation of ribosome biogenesis
EKN16_RS13200	COG1713	HD superfamily hydrolase involved in NAD metabolism
EKN16_RS13205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EKN16_RS13210	COG1534	Rna-binding protein
EKN16_RS13215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EKN16_RS13220	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EKN16_RS13225	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EKN16_RS13230	COG1305	Transglutaminase-like
EKN16_RS13240	COG0714	Associated with various cellular activities
EKN16_RS13250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKN16_RS13260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKN16_RS13275	COG1609	Transcriptional regulator
EKN16_RS13285	COG2814	Major facilitator Superfamily
EKN16_RS13290	COG0778	Nitroreductase
EKN16_RS13295	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKN16_RS13300	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EKN16_RS13300	COG1082	Xylose isomerase domain protein TIM barrel
EKN16_RS13305	COG0673	inositol 2-dehydrogenase activity
EKN16_RS13310	COG4977	sequence-specific DNA binding
EKN16_RS13310	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS13315	COG1764	response to oxidative stress
EKN16_RS13320	COG1349	DNA-binding transcription factor activity
EKN16_RS13350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EKN16_RS13380	COG1070	Carbohydrate kinase
EKN16_RS13385	COG0686	Belongs to the AlaDH PNT family
EKN16_RS13390	COG1349	DNA-binding transcription factor activity
EKN16_RS13395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EKN16_RS13455	COG0584	glycerophosphoryl diester phosphodiesterase
EKN16_RS13485	COG1177	transmembrane transport
EKN16_RS13490	COG1609	Transcriptional regulator
EKN16_RS13500	COG3693	PFAM glycoside hydrolase, family 10
EKN16_RS13505	COG1653	transport
EKN16_RS13510	COG0673	inositol 2-dehydrogenase activity
EKN16_RS13515	COG0395	ABC-type sugar transport system, permease component
EKN16_RS13520	COG1175	transmembrane transport
EKN16_RS13535	COG0395	ABC-type sugar transport system, permease component
EKN16_RS13540	COG1175	transmembrane transport
EKN16_RS13550	COG3842	ATPase activity
EKN16_RS13565	COG1609	Transcriptional regulator
EKN16_RS13570	COG1621	beta-fructofuranosidase activity
EKN16_RS13575	COG1621	beta-fructofuranosidase activity
EKN16_RS13585	COG2207	Transcriptional regulator
EKN16_RS13585	COG4753	response regulator
EKN16_RS13590	COG2972	Histidine kinase
EKN16_RS13600	COG2304	oxidoreductase activity
EKN16_RS13610	COG2255	four-way junction helicase activity
EKN16_RS13615	COG1063	alcohol dehydrogenase
EKN16_RS13620	COG2721	sulfolactate sulfo-lyase activity
EKN16_RS13625	COG0246	Mannitol dehydrogenase
EKN16_RS13630	COG3618	amidohydrolase
EKN16_RS13635	COG2169	Transcriptional regulator
EKN16_RS13665	COG1846	Transcriptional regulator
EKN16_RS13670	COG0129	dihydroxy-acid dehydratase activity
EKN16_RS13690	COG0628	permease
EKN16_RS13695	COG0768	penicillin binding
EKN16_RS13705	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EKN16_RS13720	COG5578	integral membrane protein
EKN16_RS13725	COG0513	Belongs to the DEAD box helicase family
EKN16_RS13730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKN16_RS13765	COG2814	Major facilitator Superfamily
EKN16_RS13770	COG0217	transcriptional regulatory protein
EKN16_RS13795	COG1164	Oligoendopeptidase f
EKN16_RS13800	COG0431	NADPH-dependent FMN reductase
EKN16_RS13815	COG3437	response regulator, receiver
EKN16_RS13815	COG0784	Response regulator, receiver
EKN16_RS13820	COG0584	glycerophosphoryl diester phosphodiesterase
EKN16_RS13825	COG2843	Capsule synthesis protein
EKN16_RS13835	COG2226	methyltransferase
EKN16_RS13840	COG0697	spore germination
EKN16_RS13855	COG1304	FMN binding
EKN16_RS13860	COG0363	glucosamine-6-phosphate deaminase activity
EKN16_RS13880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS13890	COG0514	ATP-dependent DNA helicase (RecQ)
EKN16_RS13895	COG0039	L-malate dehydrogenase activity
EKN16_RS13900	COG0538	isocitrate dehydrogenase activity
EKN16_RS13905	COG0372	Belongs to the citrate synthase family
EKN16_RS13910	COG0248	Ppx GppA phosphatase
EKN16_RS13915	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EKN16_RS13920	COG0628	permease
EKN16_RS13925	COG3030	protein affecting phage T7 exclusion by the F plasmid
EKN16_RS13930	COG0824	Thioesterase
EKN16_RS13940	COG0825	malonyl-CoA metabolic process
EKN16_RS13945	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EKN16_RS13955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EKN16_RS13980	COG4109	DRTGG domain
EKN16_RS13985	COG3679	Belongs to the UPF0342 family
EKN16_RS13990	COG0189	ligase activity
EKN16_RS13995	COG0189	ligase activity
EKN16_RS14000	COG0189	ligase activity
EKN16_RS14015	COG0189	ligase activity
EKN16_RS14030	COG4632	Exopolysaccharide biosynthesis protein
EKN16_RS14030	COG5434	Belongs to the glycosyl hydrolase 28 family
EKN16_RS14035	COG3546	catalase activity
EKN16_RS14050	COG1253	flavin adenine dinucleotide binding
EKN16_RS14055	COG0535	radical SAM domain protein
EKN16_RS14060	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EKN16_RS14060	COG2199	diguanylate cyclase activity
EKN16_RS14065	COG1653	transport
EKN16_RS14070	COG3833	ABC-type maltose transport systems, permease component
EKN16_RS14075	COG4209	transmembrane transport
EKN16_RS14095	COG0737	Belongs to the 5'-nucleotidase family
EKN16_RS14110	COG0314	molybdopterin synthase activity
EKN16_RS14115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EKN16_RS14125	COG0719	Fe-S assembly protein
EKN16_RS14130	COG0822	iron-sulfur transferase activity
EKN16_RS14135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKN16_RS14140	COG0719	Fe-S assembly protein
EKN16_RS14145	COG0396	ATPase activity
EKN16_RS14155	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EKN16_RS14165	COG3377	Domain of unknown function (DUF1805)
EKN16_RS14175	COG5001	Diguanylate cyclase
EKN16_RS14175	COG3300	MHYT domain
EKN16_RS14180	COG2363	Small membrane protein
EKN16_RS14205	COG2718	Belongs to the UPF0229 family
EKN16_RS14215	COG1175	transmembrane transport
EKN16_RS14225	COG4753	response regulator
EKN16_RS14225	COG2207	Transcriptional regulator
EKN16_RS14235	COG2911	Protein conserved in bacteria
EKN16_RS14235	COG3266	domain, Protein
EKN16_RS14235	COG1361	Conserved repeat domain
EKN16_RS14245	COG0395	ABC-type sugar transport system, permease component
EKN16_RS14250	COG4209	transmembrane transport
EKN16_RS14255	COG2207	Transcriptional regulator
EKN16_RS14255	COG4753	response regulator
EKN16_RS14260	COG2972	Histidine kinase
EKN16_RS14265	COG2169	Transcriptional regulator
EKN16_RS14285	COG2911	Protein conserved in bacteria
EKN16_RS14285	COG3266	domain, Protein
EKN16_RS14285	COG1361	Conserved repeat domain
EKN16_RS14295	COG2207	Transcriptional regulator
EKN16_RS14295	COG4753	response regulator
EKN16_RS14305	COG0395	ABC-type sugar transport system, permease component
EKN16_RS14310	COG4209	transmembrane transport
EKN16_RS14340	COG1473	amidohydrolase
EKN16_RS14345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKN16_RS14365	COG1473	amidohydrolase
EKN16_RS14370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKN16_RS14375	COG1126	abc transporter atp-binding protein
EKN16_RS14380	COG0765	amino acid transport
EKN16_RS14385	COG0765	amino acid transport
EKN16_RS14390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EKN16_RS14395	COG0583	DNA-binding transcription factor activity
EKN16_RS14400	COG1368	sulfuric ester hydrolase activity
EKN16_RS14415	COG2719	SpoVR family
EKN16_RS14440	COG0840	transmembrane signaling receptor activity
EKN16_RS14450	COG2766	serine protein kinase
EKN16_RS14465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKN16_RS14470	COG2002	toxin-antitoxin pair type II binding
EKN16_RS14480	COG0745	RESPONSE REGULATOR receiver
EKN16_RS14495	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EKN16_RS14505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EKN16_RS14510	COG5002	protein histidine kinase activity
EKN16_RS14510	COG3850	Histidine kinase
EKN16_RS14515	COG0745	RESPONSE REGULATOR receiver
EKN16_RS14520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKN16_RS14530	COG2197	response regulator
EKN16_RS14535	COG4585	Histidine kinase
EKN16_RS14540	COG4758	membrane
EKN16_RS14545	COG0004	ammonium transporteR
EKN16_RS14555	COG1595	DNA-templated transcription, initiation
EKN16_RS14560	COG3584	3D domain protein
EKN16_RS14565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKN16_RS14580	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EKN16_RS14585	COG0626	cystathionine gamma-synthase activity
EKN16_RS14590	COG0626	cystathionine gamma-synthase activity
EKN16_RS14595	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EKN16_RS14600	COG0598	Magnesium transport protein CorA
EKN16_RS14605	COG2270	Major facilitator Superfamily
EKN16_RS14610	COG0583	DNA-binding transcription factor activity
EKN16_RS14635	COG1733	regulation of RNA biosynthetic process
EKN16_RS14645	COG1595	DNA-templated transcription, initiation
EKN16_RS14650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EKN16_RS14655	COG1053	succinate dehydrogenase
EKN16_RS14660	COG2009	succinate dehydrogenase
EKN16_RS14665	COG0583	DNA-binding transcription factor activity
EKN16_RS14680	COG0569	domain protein
EKN16_RS14685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EKN16_RS14695	COG0322	excinuclease ABC activity
EKN16_RS14715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EKN16_RS14720	COG4208	sulfate ABC transporter
EKN16_RS14730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EKN16_RS14735	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EKN16_RS14740	COG1484	DNA-dependent DNA replication
EKN16_RS14760	COG3253	May function as heme-dependent peroxidase
EKN16_RS14770	COG1252	NADH dehydrogenase
EKN16_RS14790	COG0189	ligase activity
EKN16_RS14795	COG0667	Aldo Keto reductase
EKN16_RS14800	COG3209	COG3209 Rhs family protein
EKN16_RS14830	COG0316	Belongs to the HesB IscA family
EKN16_RS14835	COG1272	protein, Hemolysin III
EKN16_RS14840	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EKN16_RS14845	COG1252	NADH dehydrogenase
EKN16_RS14850	COG4844	belongs to the
EKN16_RS14855	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EKN16_RS14860	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS14870	COG1612	heme a metabolic process
EKN16_RS14890	COG2244	polysaccharide biosynthetic process
EKN16_RS14905	COG0561	phosphatase activity
EKN16_RS14910	COG0768	penicillin binding
EKN16_RS14955	COG0109	protoheme IX farnesyltransferase activity
EKN16_RS14975	COG1988	membrane-bound metal-dependent
EKN16_RS14985	COG0180	Tryptophanyl-tRNA synthetase
EKN16_RS15000	COG0701	Predicted permease
EKN16_RS15020	COG0840	transmembrane signaling receptor activity
EKN16_RS15030	COG3458	cephalosporin-C deacetylase activity
EKN16_RS15040	COG3693	PFAM glycoside hydrolase, family 10
EKN16_RS15050	COG0395	ABC-type sugar transport system, permease component
EKN16_RS15060	COG1653	transport
EKN16_RS15065	COG0673	inositol 2-dehydrogenase activity
EKN16_RS15075	COG0673	inositol 2-dehydrogenase activity
EKN16_RS15080	COG3583	domain protein
EKN16_RS15080	COG3584	3D domain protein
EKN16_RS15085	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EKN16_RS15085	COG0662	Cupin 2, conserved barrel domain protein
EKN16_RS15090	COG4191	Histidine kinase
EKN16_RS15100	COG1309	transcriptional regulator
EKN16_RS15105	COG2340	Cysteine-rich secretory protein family
EKN16_RS15115	COG5002	protein histidine kinase activity
EKN16_RS15120	COG0745	RESPONSE REGULATOR receiver
EKN16_RS15140	COG2340	Cysteine-rich secretory protein family
EKN16_RS15145	COG3250	beta-galactosidase activity
EKN16_RS15150	COG2207	Transcriptional regulator
EKN16_RS15160	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS15165	COG0583	DNA-binding transcription factor activity
EKN16_RS15170	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKN16_RS15175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EKN16_RS15180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EKN16_RS15225	COG1113	amino acid transport
EKN16_RS15265	COG1227	inorganic diphosphatase activity
EKN16_RS15270	COG0024	Methionine aminopeptidase
EKN16_RS15280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EKN16_RS15285	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EKN16_RS15295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EKN16_RS15320	COG1131	(ABC) transporter
EKN16_RS15355	COG1653	transport
EKN16_RS15360	COG0395	ABC-type sugar transport system, permease component
EKN16_RS15365	COG4209	transmembrane transport
EKN16_RS15370	COG2972	Histidine kinase
EKN16_RS15375	COG3279	Response regulator of the LytR AlgR family
EKN16_RS15425	COG2183	response to ionizing radiation
EKN16_RS15430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKN16_RS15440	COG0586	Pfam SNARE associated Golgi protein
EKN16_RS15465	COG1587	Uroporphyrinogen-III synthase
EKN16_RS15470	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKN16_RS15475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKN16_RS15480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKN16_RS15495	COG1136	(ABC) transporter
EKN16_RS15500	COG0577	efflux transmembrane transporter activity
EKN16_RS15515	COG3706	GGDEF domain
EKN16_RS15520	COG3706	GGDEF domain
EKN16_RS15535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKN16_RS15555	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EKN16_RS15560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EKN16_RS15565	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EKN16_RS15575	COG0628	permease
EKN16_RS15585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EKN16_RS15590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKN16_RS15595	COG0739	heme binding
EKN16_RS15605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EKN16_RS15610	COG1131	(ABC) transporter
EKN16_RS15625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKN16_RS15645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EKN16_RS15650	COG1316	TRANSCRIPTIONal
EKN16_RS15655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EKN16_RS15660	COG1396	sequence-specific DNA binding
EKN16_RS15680	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EKN16_RS15685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EKN16_RS15710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKN16_RS15715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EKN16_RS15725	COG3307	-O-antigen
EKN16_RS15735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EKN16_RS15745	COG1396	sequence-specific DNA binding
EKN16_RS15755	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS15760	COG0067	glutamate synthase
EKN16_RS15760	COG0069	glutamate synthase activity
EKN16_RS15760	COG0070	glutamate synthase
EKN16_RS15770	COG1511	domain protein
EKN16_RS15775	COG1309	transcriptional regulator
EKN16_RS15780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EKN16_RS15805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKN16_RS15815	COG0791	NLP P60 protein
EKN16_RS15815	COG1388	LysM domain
EKN16_RS15815	COG3103	Sh3 type 3 domain protein
EKN16_RS15835	COG0488	(ABC) transporter
EKN16_RS15840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EKN16_RS15845	COG1413	lyase activity
EKN16_RS15875	COG0745	RESPONSE REGULATOR receiver
EKN16_RS15880	COG1408	metallophosphoesterase
EKN16_RS15920	COG2132	Multicopper oxidase
EKN16_RS15930	COG1472	Belongs to the glycosyl hydrolase 3 family
EKN16_RS15940	COG0800	Aldolase
EKN16_RS15955	COG2010	Cytochrome c
EKN16_RS15970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EKN16_RS15990	COG3852	Histidine kinase
EKN16_RS15995	COG2081	HI0933 family
EKN16_RS16010	COG4473	ABC transporter
EKN16_RS16015	COG1131	(ABC) transporter
EKN16_RS16025	COG1070	Carbohydrate kinase
EKN16_RS16045	COG2197	response regulator
EKN16_RS16065	COG1653	transport
EKN16_RS16070	COG4753	response regulator
EKN16_RS16070	COG2207	Transcriptional regulator
EKN16_RS16075	COG2972	Histidine kinase
EKN16_RS16090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EKN16_RS16095	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS16110	COG0673	inositol 2-dehydrogenase activity
EKN16_RS16115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EKN16_RS16125	COG0395	ABC-type sugar transport system, permease component
EKN16_RS16140	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EKN16_RS16140	COG3291	Pkd domain containing protein
EKN16_RS16170	COG1653	transport
EKN16_RS16210	COG3231	kanamycin kinase activity
EKN16_RS16225	COG1011	Hydrolase
EKN16_RS16235	COG0383	alpha-mannosidase activity
EKN16_RS16250	COG0395	ABC-type sugar transport system, permease component
EKN16_RS16260	COG1653	transport
EKN16_RS16265	COG2207	Transcriptional regulator
EKN16_RS16265	COG4753	response regulator
EKN16_RS16270	COG2972	Histidine kinase
EKN16_RS16295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EKN16_RS16305	COG2205	protein histidine kinase activity
EKN16_RS16315	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EKN16_RS16320	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EKN16_RS16335	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS16380	COG1132	(ABC) transporter
EKN16_RS16390	COG1132	(ABC) transporter
EKN16_RS16395	COG2223	nitrite transmembrane transporter activity
EKN16_RS16400	COG1136	(ABC) transporter
EKN16_RS16400	COG0577	efflux transmembrane transporter activity
EKN16_RS16405	COG1136	(ABC) transporter
EKN16_RS16460	COG0395	ABC-type sugar transport system, permease component
EKN16_RS16465	COG4209	transmembrane transport
EKN16_RS16475	COG4977	sequence-specific DNA binding
EKN16_RS16475	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS16480	COG1595	DNA-templated transcription, initiation
EKN16_RS16485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKN16_RS16490	COG4989	oxidoreductase activity
EKN16_RS16495	COG1511	domain protein
EKN16_RS16510	COG0546	phosphoglycolate phosphatase activity
EKN16_RS16535	COG0095	Lipoate-protein ligase
EKN16_RS16540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EKN16_RS16545	COG1704	LemA family
EKN16_RS16555	COG2814	Major facilitator Superfamily
EKN16_RS16575	COG0673	inositol 2-dehydrogenase activity
EKN16_RS16610	COG1501	Belongs to the glycosyl hydrolase 31 family
EKN16_RS16615	COG3119	arylsulfatase activity
EKN16_RS16620	COG0395	ABC-type sugar transport system, permease component
EKN16_RS16625	COG1175	transmembrane transport
EKN16_RS16640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS16640	COG2207	Transcriptional regulator
EKN16_RS16645	COG0395	ABC-type sugar transport system, permease component
EKN16_RS16650	COG1175	transmembrane transport
EKN16_RS16675	COG1361	Conserved repeat domain
EKN16_RS16675	COG3266	domain, Protein
EKN16_RS16675	COG2911	Protein conserved in bacteria
EKN16_RS16680	COG2972	Histidine kinase
EKN16_RS16690	COG2207	Transcriptional regulator
EKN16_RS16720	COG4753	response regulator
EKN16_RS16720	COG2207	Transcriptional regulator
EKN16_RS16725	COG2972	Histidine kinase
EKN16_RS16740	COG0395	ABC-type sugar transport system, permease component
EKN16_RS16745	COG1175	transmembrane transport
EKN16_RS16750	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS16760	COG0187	DNA topoisomerase II activity
EKN16_RS16785	COG1136	(ABC) transporter
EKN16_RS16820	COG0367	asparagine synthase
EKN16_RS16865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EKN16_RS16890	COG0277	FAD linked oxidase domain protein
EKN16_RS16895	COG1803	Methylglyoxal synthase
EKN16_RS16925	COG1361	Conserved repeat domain
EKN16_RS16925	COG2911	Protein conserved in bacteria
EKN16_RS16925	COG3266	domain, Protein
EKN16_RS16930	COG1361	Conserved repeat domain
EKN16_RS16930	COG2911	Protein conserved in bacteria
EKN16_RS16930	COG3266	domain, Protein
EKN16_RS16935	COG1361	Conserved repeat domain
EKN16_RS16935	COG2911	Protein conserved in bacteria
EKN16_RS16935	COG3266	domain, Protein
EKN16_RS16945	COG0395	ABC-type sugar transport system, permease component
EKN16_RS16950	COG4209	transmembrane transport
EKN16_RS16955	COG1653	transport
EKN16_RS16960	COG0745	RESPONSE REGULATOR receiver
EKN16_RS16975	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS16985	COG0129	dihydroxy-acid dehydratase activity
EKN16_RS17005	COG1802	Transcriptional regulator
EKN16_RS17010	COG3693	PFAM glycoside hydrolase, family 10
EKN16_RS17020	COG0395	ABC-type sugar transport system, permease component
EKN16_RS17025	COG1175	transmembrane transport
EKN16_RS17040	COG3275	phosphorelay sensor kinase activity
EKN16_RS17050	COG2207	Transcriptional regulator
EKN16_RS17065	COG0395	ABC-type sugar transport system, permease component
EKN16_RS17070	COG1175	transmembrane transport
EKN16_RS17085	COG3279	Response regulator of the LytR AlgR family
EKN16_RS17095	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS17095	COG4977	sequence-specific DNA binding
EKN16_RS17100	COG1940	carbohydrate kinase activity
EKN16_RS17115	COG2755	lipolytic protein G-D-S-L family
EKN16_RS17120	COG2207	Transcriptional regulator
EKN16_RS17125	COG1063	alcohol dehydrogenase
EKN16_RS17130	COG1063	alcohol dehydrogenase
EKN16_RS17135	COG3266	domain, Protein
EKN16_RS17135	COG1361	Conserved repeat domain
EKN16_RS17135	COG2911	Protein conserved in bacteria
EKN16_RS17140	COG0653	protein targeting
EKN16_RS17155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EKN16_RS17165	COG1063	alcohol dehydrogenase
EKN16_RS17190	COG0395	ABC-type sugar transport system, permease component
EKN16_RS17195	COG1175	transmembrane transport
EKN16_RS17205	COG3275	phosphorelay sensor kinase activity
EKN16_RS17210	COG2207	Transcriptional regulator
EKN16_RS17215	COG1312	Catalyzes the dehydration of D-mannonate
EKN16_RS17255	COG1312	Catalyzes the dehydration of D-mannonate
EKN16_RS17290	COG0395	ABC-type sugar transport system, permease component
EKN16_RS17305	COG3842	ATPase activity
EKN16_RS17315	COG2972	Histidine kinase
EKN16_RS17320	COG4753	response regulator
EKN16_RS17320	COG2207	Transcriptional regulator
EKN16_RS17330	COG1668	transmembrane transport
EKN16_RS17335	COG4152	abc transporter atp-binding protein
EKN16_RS17365	COG3336	cytochrome c oxidase
EKN16_RS17395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS17415	COG2259	Doxx family
EKN16_RS17445	COG1131	(ABC) transporter
EKN16_RS17465	COG2814	Major facilitator Superfamily
EKN16_RS17470	COG0640	Transcriptional regulator
EKN16_RS17475	COG0702	epimerase
EKN16_RS17485	COG1846	Transcriptional regulator
EKN16_RS17495	COG0598	Magnesium transport protein CorA
EKN16_RS17505	COG2315	Protein conserved in bacteria
EKN16_RS17525	COG2814	Major facilitator Superfamily
EKN16_RS17530	COG2801	Transposase and inactivated derivatives
EKN16_RS17535	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS17535	COG2207	Transcriptional regulator
EKN16_RS17545	COG0673	inositol 2-dehydrogenase activity
EKN16_RS17565	COG2205	protein histidine kinase activity
EKN16_RS17570	COG1876	peptidase activity
EKN16_RS17585	COG2205	protein histidine kinase activity
EKN16_RS17595	COG4474	Belongs to the UPF0398 family
EKN16_RS17600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKN16_RS17610	COG1285	pathogenesis
EKN16_RS17620	COG0531	amino acid
EKN16_RS17630	COG0372	Belongs to the citrate synthase family
EKN16_RS17635	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EKN16_RS17640	COG1960	acyl-CoA dehydrogenase activity
EKN16_RS17645	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKN16_RS17650	COG0183	Belongs to the thiolase family
EKN16_RS17655	COG1960	acyl-CoA dehydrogenase activity
EKN16_RS17665	COG0463	Glycosyl transferase, family 2
EKN16_RS17685	COG2814	Major facilitator Superfamily
EKN16_RS17690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EKN16_RS17690	COG2755	lipolytic protein G-D-S-L family
EKN16_RS17695	COG2201	protein-glutamate methylesterase activity
EKN16_RS17710	COG0395	ABC-type sugar transport system, permease component
EKN16_RS17715	COG4209	transmembrane transport
EKN16_RS17720	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EKN16_RS17725	COG2390	Transcriptional regulator
EKN16_RS17730	COG1079	Belongs to the binding-protein-dependent transport system permease family
EKN16_RS17735	COG4603	Belongs to the binding-protein-dependent transport system permease family
EKN16_RS17740	COG3845	ABC transporter
EKN16_RS17745	COG1744	ABC transporter substrate-binding protein PnrA-like
EKN16_RS17750	COG1349	DNA-binding transcription factor activity
EKN16_RS17755	COG3842	ATPase activity
EKN16_RS17760	COG0395	ABC-type sugar transport system, permease component
EKN16_RS17765	COG1175	transmembrane transport
EKN16_RS17775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EKN16_RS17785	COG1796	DNA polymerase
EKN16_RS17785	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EKN16_RS17790	COG1796	DNA polymerase
EKN16_RS17790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EKN16_RS17805	COG0860	N-Acetylmuramoyl-L-alanine amidase
EKN16_RS17810	COG3481	metal-dependent phosphohydrolase, HD sub domain
EKN16_RS17815	COG1956	GAF domain-containing protein
EKN16_RS17830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EKN16_RS17835	COG3541	Predicted nucleotidyltransferase
EKN16_RS17855	COG1160	GTP binding
EKN16_RS17865	COG3386	PFAM SMP-30 Gluconolaconase
EKN16_RS17875	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EKN16_RS17880	COG1335	isochorismatase
EKN16_RS17895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKN16_RS17915	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EKN16_RS17920	COG2954	triphosphatase activity
EKN16_RS17925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKN16_RS17930	COG0686	Belongs to the AlaDH PNT family
EKN16_RS17935	COG2508	Transcriptional regulator
EKN16_RS17935	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EKN16_RS17940	COG1113	amino acid transport
EKN16_RS17945	COG1309	transcriptional regulator
EKN16_RS17990	COG0840	transmembrane signaling receptor activity
EKN16_RS18010	COG2032	superoxide dismutase activity
EKN16_RS18015	COG0456	acetyltransferase
EKN16_RS18030	COG0477	Major facilitator Superfamily
EKN16_RS18055	COG3693	PFAM glycoside hydrolase, family 10
EKN16_RS18090	COG4753	response regulator
EKN16_RS18090	COG2207	Transcriptional regulator
EKN16_RS18095	COG2972	Histidine kinase
EKN16_RS18105	COG4209	transmembrane transport
EKN16_RS18110	COG0395	ABC-type sugar transport system, permease component
EKN16_RS18115	COG1653	transport
EKN16_RS18175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKN16_RS18190	COG1396	sequence-specific DNA binding
EKN16_RS18205	COG3459	Glycosyltransferase 36 associated
EKN16_RS18215	COG0326	Molecular chaperone. Has ATPase activity
EKN16_RS18230	COG1122	ATPase activity
EKN16_RS18235	COG1122	ATPase activity
EKN16_RS18265	COG0673	inositol 2-dehydrogenase activity
EKN16_RS18270	COG0395	ABC-type sugar transport system, permease component
EKN16_RS18275	COG1175	transmembrane transport
EKN16_RS18285	COG1361	Conserved repeat domain
EKN16_RS18295	COG2972	Histidine kinase
EKN16_RS18295	COG0745	RESPONSE REGULATOR receiver
EKN16_RS18320	COG0488	(ABC) transporter
EKN16_RS18325	COG0531	amino acid
EKN16_RS18330	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS18335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EKN16_RS18345	COG3655	Transcriptional regulator
EKN16_RS18365	COG0840	transmembrane signaling receptor activity
EKN16_RS18375	COG0531	amino acid
EKN16_RS18380	COG0697	spore germination
EKN16_RS18385	COG3706	GGDEF domain
EKN16_RS18390	COG4221	oxidoreductase activity
EKN16_RS18405	COG4221	oxidoreductase activity
EKN16_RS18430	COG0604	alcohol dehydrogenase
EKN16_RS18435	COG1733	regulation of RNA biosynthetic process
EKN16_RS18455	COG0745	RESPONSE REGULATOR receiver
EKN16_RS18460	COG2205	protein histidine kinase activity
EKN16_RS18465	COG1309	transcriptional regulator
EKN16_RS18470	COG2814	Major facilitator Superfamily
EKN16_RS18485	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS18490	COG4948	Mandelate Racemase Muconate Lactonizing
EKN16_RS18495	COG1653	transport
EKN16_RS18500	COG0395	ABC-type sugar transport system, permease component
EKN16_RS18505	COG4209	transmembrane transport
EKN16_RS18520	COG1136	(ABC) transporter
EKN16_RS18525	COG0577	efflux transmembrane transporter activity
EKN16_RS18535	COG3706	GGDEF domain
EKN16_RS18550	COG1653	transport
EKN16_RS18555	COG0395	ABC-type sugar transport system, permease component
EKN16_RS18560	COG4209	transmembrane transport
EKN16_RS18570	COG2207	Transcriptional regulator
EKN16_RS18570	COG4753	response regulator
EKN16_RS18575	COG3275	phosphorelay sensor kinase activity
EKN16_RS18590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKN16_RS18595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKN16_RS18600	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS18605	COG3250	beta-galactosidase activity
EKN16_RS18610	COG0395	ABC-type sugar transport system, permease component
EKN16_RS18615	COG1175	transmembrane transport
EKN16_RS18625	COG2207	Transcriptional regulator
EKN16_RS18625	COG4753	response regulator
EKN16_RS18630	COG2972	Histidine kinase
EKN16_RS18655	COG5002	protein histidine kinase activity
EKN16_RS18710	COG2911	Protein conserved in bacteria
EKN16_RS18710	COG3266	domain, Protein
EKN16_RS18710	COG1361	Conserved repeat domain
EKN16_RS18715	COG0513	Belongs to the DEAD box helicase family
EKN16_RS18725	COG0583	DNA-binding transcription factor activity
EKN16_RS18735	COG0640	Transcriptional regulator
EKN16_RS18745	COG0628	permease
EKN16_RS18760	COG0745	RESPONSE REGULATOR receiver
EKN16_RS18805	COG1595	DNA-templated transcription, initiation
EKN16_RS18820	COG0477	Major facilitator Superfamily
EKN16_RS18835	COG1335	isochorismatase
EKN16_RS18840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKN16_RS18850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EKN16_RS18865	COG1361	Conserved repeat domain
EKN16_RS18870	COG0515	serine threonine protein kinase
EKN16_RS18870	COG2815	serine threonine protein kinase
EKN16_RS18895	COG2207	Transcriptional regulator
EKN16_RS18895	COG3708	Transcriptional regulator
EKN16_RS18905	COG0363	glucosamine-6-phosphate deaminase activity
EKN16_RS18915	COG2207	Transcriptional regulator
EKN16_RS18955	COG0514	ATP-dependent DNA helicase (RecQ)
EKN16_RS19080	COG2966	Psort location CytoplasmicMembrane, score
EKN16_RS19100	COG2972	Histidine kinase
EKN16_RS19100	COG0745	RESPONSE REGULATOR receiver
EKN16_RS19105	COG3279	Response regulator of the LytR AlgR family
EKN16_RS19125	COG3279	Response regulator of the LytR AlgR family
EKN16_RS19145	COG1361	Conserved repeat domain
EKN16_RS19145	COG2911	Protein conserved in bacteria
EKN16_RS19145	COG3266	domain, Protein
EKN16_RS19170	COG0693	protein deglycase activity
EKN16_RS19190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EKN16_RS19195	COG0561	phosphatase activity
EKN16_RS19205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS19210	COG0395	ABC-type sugar transport system, permease component
EKN16_RS19215	COG4209	transmembrane transport
EKN16_RS19225	COG2207	Transcriptional regulator
EKN16_RS19225	COG4753	response regulator
EKN16_RS19235	COG2207	Transcriptional regulator
EKN16_RS19235	COG4753	response regulator
EKN16_RS19240	COG3231	kanamycin kinase activity
EKN16_RS19250	COG0464	growth
EKN16_RS19275	COG2017	converts alpha-aldose to the beta-anomer
EKN16_RS19280	COG1486	melibiose metabolic process
EKN16_RS19285	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS19290	COG0395	ABC-type sugar transport system, permease component
EKN16_RS19295	COG4209	transmembrane transport
EKN16_RS19305	COG2207	Transcriptional regulator
EKN16_RS19305	COG4753	response regulator
EKN16_RS19310	COG3275	phosphorelay sensor kinase activity
EKN16_RS19380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EKN16_RS19385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EKN16_RS19400	COG2192	nodulation
EKN16_RS19415	COG0717	Belongs to the dCTP deaminase family
EKN16_RS19425	COG1132	(ABC) transporter
EKN16_RS19430	COG1132	(ABC) transporter
EKN16_RS19435	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS19440	COG0318	PFAM AMP-dependent synthetase and ligase
EKN16_RS19445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKN16_RS19515	COG0494	nUDIX hydrolase
EKN16_RS19530	COG2003	Belongs to the UPF0758 family
EKN16_RS19575	COG0582	viral genome integration into host DNA
EKN16_RS19580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKN16_RS19585	COG1597	lipid kinase activity
EKN16_RS19595	COG4496	protein, YerC YecD
EKN16_RS19605	COG0306	phosphate transporter
EKN16_RS19610	COG1392	Phosphate transport regulator
EKN16_RS19615	COG1470	cell adhesion involved in biofilm formation
EKN16_RS19620	COG2169	Transcriptional regulator
EKN16_RS19620	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS19625	COG5285	phytanoyl-CoA dioxygenase
EKN16_RS19630	COG2205	protein histidine kinase activity
EKN16_RS19635	COG0745	RESPONSE REGULATOR receiver
EKN16_RS19645	COG0577	efflux transmembrane transporter activity
EKN16_RS19650	COG1136	(ABC) transporter
EKN16_RS19655	COG5002	protein histidine kinase activity
EKN16_RS19660	COG0745	RESPONSE REGULATOR receiver
EKN16_RS19680	COG0840	transmembrane signaling receptor activity
EKN16_RS19730	COG0151	Belongs to the GarS family
EKN16_RS19735	COG0138	bifunctional purine biosynthesis protein purh
EKN16_RS19740	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EKN16_RS19745	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EKN16_RS19750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EKN16_RS19755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKN16_RS19760	COG0047	phosphoribosylformylglycinamidine synthase activity
EKN16_RS19765	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKN16_RS19770	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EKN16_RS19775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EKN16_RS19780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EKN16_RS19785	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EKN16_RS19795	COG2252	PERMEase
EKN16_RS19805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EKN16_RS19810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EKN16_RS19810	COG0519	Catalyzes the synthesis of GMP from XMP
EKN16_RS19825	COG1595	DNA-templated transcription, initiation
EKN16_RS19845	COG1305	Transglutaminase-like
EKN16_RS19855	COG0714	Associated with various cellular activities
EKN16_RS19860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EKN16_RS19875	COG4555	ABC transporter
EKN16_RS19885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EKN16_RS19900	COG0483	inositol monophosphate 1-phosphatase activity
EKN16_RS19905	COG0730	response to heat
EKN16_RS19915	COG4294	response to UV
EKN16_RS19925	COG1181	Belongs to the D-alanine--D-alanine ligase family
EKN16_RS19935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EKN16_RS19940	COG1414	Transcriptional regulator
EKN16_RS19975	COG3557	Belongs to the UPF0374 family
EKN16_RS19985	COG1091	dTDP-4-dehydrorhamnose reductase activity
EKN16_RS20000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EKN16_RS20005	COG0194	GDP metabolic process
EKN16_RS20010	COG2267	carboxylic ester hydrolase activity
EKN16_RS20020	COG1069	ribulokinase activity
EKN16_RS20055	COG0783	Belongs to the Dps family
EKN16_RS20065	COG0534	Mate efflux family protein
EKN16_RS20070	COG0488	(ABC) transporter
EKN16_RS20085	COG1361	Conserved repeat domain
EKN16_RS20110	COG1653	transport
EKN16_RS20115	COG0395	ABC-type sugar transport system, permease component
EKN16_RS20120	COG4209	transmembrane transport
EKN16_RS20125	COG2972	Histidine kinase
EKN16_RS20130	COG2207	Transcriptional regulator
EKN16_RS20130	COG2207	Transcriptional regulator
EKN16_RS20130	COG4753	response regulator
EKN16_RS20130	COG4753	response regulator
EKN16_RS20145	COG3250	beta-galactosidase activity
EKN16_RS20160	COG0024	Methionine aminopeptidase
EKN16_RS20180	COG0318	PFAM AMP-dependent synthetase and ligase
EKN16_RS20185	COG1960	acyl-CoA dehydrogenase activity
EKN16_RS20190	COG0183	Belongs to the thiolase family
EKN16_RS20195	COG1024	Enoyl-CoA hydratase
EKN16_RS20195	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKN16_RS20200	COG2181	nitrate reductase activity
EKN16_RS20200	COG0247	lactate metabolic process
EKN16_RS20205	COG2086	electron transfer activity
EKN16_RS20210	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EKN16_RS20220	COG3693	PFAM glycoside hydrolase, family 10
EKN16_RS20225	COG2326	polyphosphate kinase activity
EKN16_RS20235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EKN16_RS20240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKN16_RS20250	COG0398	Pfam SNARE associated Golgi protein
EKN16_RS20265	COG4129	membrane
EKN16_RS20270	COG4335	DNA alkylation repair
EKN16_RS20275	COG4191	Histidine kinase
EKN16_RS20280	COG1970	mechanosensitive ion channel activity
EKN16_RS20285	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EKN16_RS20315	COG0697	spore germination
EKN16_RS20320	COG1696	Membrane protein involved in D-alanine export
EKN16_RS20340	COG0745	RESPONSE REGULATOR receiver
EKN16_RS20345	COG0784	Response regulator, receiver
EKN16_RS20345	COG2205	protein histidine kinase activity
EKN16_RS20345	COG5002	protein histidine kinase activity
EKN16_RS20360	COG2770	Histidine kinase
EKN16_RS20360	COG3437	response regulator, receiver
EKN16_RS20390	COG0667	Aldo Keto reductase
EKN16_RS20410	COG2814	Major facilitator Superfamily
EKN16_RS20415	COG0789	Transcriptional regulator
EKN16_RS20420	COG1064	alcohol dehydrogenase
EKN16_RS20430	COG5002	protein histidine kinase activity
EKN16_RS20435	COG0745	RESPONSE REGULATOR receiver
EKN16_RS20440	COG1522	sequence-specific DNA binding
EKN16_RS20450	COG1971	Probably functions as a manganese efflux pump
EKN16_RS20460	COG0598	Magnesium transport protein CorA
EKN16_RS20475	COG2197	response regulator
EKN16_RS20480	COG4585	Histidine kinase
EKN16_RS20485	COG0842	Transport permease protein
EKN16_RS20490	COG1131	(ABC) transporter
EKN16_RS20525	COG3842	ATPase activity
EKN16_RS20530	COG1178	ABC-type Fe3 transport system permease component
EKN16_RS20535	COG1178	ABC-type Fe3 transport system permease component
EKN16_RS20580	COG0395	ABC-type sugar transport system, permease component
EKN16_RS20585	COG1175	transmembrane transport
EKN16_RS20595	COG2188	Transcriptional regulator
EKN16_RS20605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EKN16_RS20615	COG3383	formate dehydrogenase (NAD+) activity
EKN16_RS20620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EKN16_RS20625	COG0386	Belongs to the glutathione peroxidase family
EKN16_RS20630	COG2205	protein histidine kinase activity
EKN16_RS20665	COG0673	inositol 2-dehydrogenase activity
EKN16_RS20710	COG0456	acetyltransferase
EKN16_RS20735	COG0194	GDP metabolic process
EKN16_RS20750	COG0477	Major facilitator Superfamily
EKN16_RS20755	COG1846	Transcriptional regulator
EKN16_RS20770	COG1842	Phage shock protein A
EKN16_RS20775	COG4585	Histidine kinase
EKN16_RS20775	COG2203	Gaf domain
EKN16_RS20780	COG2197	response regulator
EKN16_RS20785	COG0431	NADPH-dependent FMN reductase
EKN16_RS20825	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EKN16_RS20835	COG0789	Transcriptional regulator
EKN16_RS20845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKN16_RS20855	COG0492	ferredoxin-NADP+ reductase activity
EKN16_RS20880	COG2733	membrane
EKN16_RS20885	COG1175	transmembrane transport
EKN16_RS20890	COG0395	ABC-type sugar transport system, permease component
EKN16_RS20895	COG1653	transport
EKN16_RS20910	COG1486	melibiose metabolic process
EKN16_RS20935	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS20935	COG2207	Transcriptional regulator
EKN16_RS20960	COG1358	cellular component organization or biogenesis
EKN16_RS20975	COG0861	Integral membrane protein TerC family
EKN16_RS20980	COG2310	stress, protein
EKN16_RS20985	COG2310	stress, protein
EKN16_RS20990	COG2310	stress, protein
EKN16_RS20995	COG2310	stress, protein
EKN16_RS21015	COG1741	Belongs to the pirin family
EKN16_RS21035	COG0210	DNA helicase
EKN16_RS21055	COG0789	Transcriptional regulator
EKN16_RS21065	COG2409	Drug exporters of the RND superfamily
EKN16_RS21075	COG2116	formate transmembrane transporter activity
EKN16_RS21080	COG1136	(ABC) transporter
EKN16_RS21085	COG0604	alcohol dehydrogenase
EKN16_RS21105	COG1309	transcriptional regulator
EKN16_RS21115	COG1940	carbohydrate kinase activity
EKN16_RS21125	COG0501	Belongs to the peptidase M48B family
EKN16_RS21135	COG0716	FMN binding
EKN16_RS21145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKN16_RS21150	COG3119	arylsulfatase activity
EKN16_RS21155	COG4191	Histidine kinase
EKN16_RS21170	COG3341	Caulimovirus viroplasmin
EKN16_RS21170	COG0328	RNA-DNA hybrid ribonuclease activity
EKN16_RS21180	COG0640	Transcriptional regulator
EKN16_RS21220	COG0726	polysaccharide deacetylase
EKN16_RS21220	COG1649	PFAM Uncharacterised BCR, COG1649
EKN16_RS21230	COG4715	Zinc finger, swim domain protein
EKN16_RS21235	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EKN16_RS21240	COG4221	oxidoreductase activity
EKN16_RS21245	COG3850	Histidine kinase
EKN16_RS21245	COG5002	protein histidine kinase activity
EKN16_RS21255	COG0840	transmembrane signaling receptor activity
EKN16_RS21265	COG0667	Aldo Keto reductase
EKN16_RS21325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKN16_RS21330	COG1472	Belongs to the glycosyl hydrolase 3 family
EKN16_RS21340	COG3944	biosynthesis protein
EKN16_RS21345	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKN16_RS21360	COG0367	asparagine synthase
EKN16_RS21370	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS21375	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS21385	COG0726	polysaccharide deacetylase
EKN16_RS21395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EKN16_RS21430	COG0154	amidase activity
EKN16_RS21445	COG3279	Response regulator of the LytR AlgR family
EKN16_RS21450	COG4251	negative regulation of phosphorylation
EKN16_RS21455	COG3266	domain, Protein
EKN16_RS21455	COG2911	Protein conserved in bacteria
EKN16_RS21455	COG1361	Conserved repeat domain
EKN16_RS21465	COG0737	Belongs to the 5'-nucleotidase family
EKN16_RS21470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EKN16_RS21475	COG1725	Transcriptional regulator
EKN16_RS21485	COG1131	(ABC) transporter
EKN16_RS21490	COG1733	regulation of RNA biosynthetic process
EKN16_RS21510	COG0662	Cupin 2, conserved barrel domain protein
EKN16_RS21515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS21520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS21520	COG2207	Transcriptional regulator
EKN16_RS21540	COG0395	ABC-type sugar transport system, permease component
EKN16_RS21545	COG1175	transmembrane transport
EKN16_RS21560	COG2972	Histidine kinase
EKN16_RS21570	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EKN16_RS21585	COG1234	tRNA 3'-trailer cleavage
EKN16_RS21620	COG0789	Transcriptional regulator
EKN16_RS21635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EKN16_RS21635	COG1605	Chorismate mutase
EKN16_RS21665	COG0179	Fumarylacetoacetate (FAA) hydrolase
EKN16_RS21675	COG4948	Mandelate Racemase Muconate Lactonizing
EKN16_RS21680	COG1802	Transcriptional regulator
EKN16_RS21685	COG2188	Transcriptional regulator
EKN16_RS21710	COG3654	unkown
EKN16_RS21720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKN16_RS21725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKN16_RS21730	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EKN16_RS21735	COG2207	Transcriptional regulator
EKN16_RS21740	COG1070	Carbohydrate kinase
EKN16_RS21745	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
EKN16_RS21755	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS21755	COG2169	Transcriptional regulator
EKN16_RS21775	COG1653	transport
EKN16_RS21780	COG0395	ABC-type sugar transport system, permease component
EKN16_RS21785	COG4209	transmembrane transport
EKN16_RS21790	COG2972	Histidine kinase
EKN16_RS21795	COG2207	Transcriptional regulator
EKN16_RS21795	COG4753	response regulator
EKN16_RS21800	COG0395	ABC-type sugar transport system, permease component
EKN16_RS21810	COG1653	transport
EKN16_RS21825	COG1309	transcriptional regulator
EKN16_RS21865	COG0604	alcohol dehydrogenase
EKN16_RS21870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EKN16_RS21875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EKN16_RS21905	COG0395	ABC-type sugar transport system, permease component
EKN16_RS21910	COG1940	carbohydrate kinase activity
EKN16_RS21915	COG1309	transcriptional regulator
EKN16_RS21925	COG1070	Carbohydrate kinase
EKN16_RS21930	COG1172	Belongs to the binding-protein-dependent transport system permease family
EKN16_RS21935	COG1129	ABC transporter
EKN16_RS21940	COG1879	ABC-type sugar transport system periplasmic component
EKN16_RS21945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EKN16_RS21965	COG3279	Response regulator of the LytR AlgR family
EKN16_RS21970	COG0745	RESPONSE REGULATOR receiver
EKN16_RS21970	COG2972	Histidine kinase
EKN16_RS21975	COG1361	Conserved repeat domain
EKN16_RS21975	COG2911	Protein conserved in bacteria
EKN16_RS21975	COG3266	domain, Protein
EKN16_RS21985	COG0840	transmembrane signaling receptor activity
EKN16_RS22035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EKN16_RS22040	COG0557	exoribonuclease II activity
EKN16_RS22045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EKN16_RS22055	COG0148	phosphopyruvate hydratase activity
EKN16_RS22065	COG0149	triose-phosphate isomerase activity
EKN16_RS22070	COG0126	phosphoglycerate kinase activity
EKN16_RS22090	COG0740	serine-type endopeptidase activity
EKN16_RS22105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKN16_RS22110	COG1481	regulation of sporulation
EKN16_RS22115	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EKN16_RS22120	COG1660	Displays ATPase and GTPase activities
EKN16_RS22125	COG1940	carbohydrate kinase activity
EKN16_RS22135	COG0457	Tetratricopeptide repeat
EKN16_RS22145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EKN16_RS22145	COG0140	phosphoribosyl-ATP diphosphatase activity
EKN16_RS22150	COG0107	imidazoleglycerol-phosphate synthase activity
EKN16_RS22155	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EKN16_RS22160	COG0131	Imidazoleglycerol-phosphate dehydratase
EKN16_RS22165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EKN16_RS22170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EKN16_RS22175	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EKN16_RS22180	COG0110	maltose O-acetyltransferase activity
EKN16_RS22185	COG0546	phosphoglycolate phosphatase activity
EKN16_RS22190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EKN16_RS22195	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EKN16_RS22200	COG3842	ATPase activity
EKN16_RS22205	COG2508	Transcriptional regulator
EKN16_RS22270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EKN16_RS22275	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EKN16_RS22280	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKN16_RS22285	COG3852	Histidine kinase
EKN16_RS22300	COG0254	rRNA binding
EKN16_RS22310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EKN16_RS22315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKN16_RS22320	COG0191	fructose-bisphosphate aldolase activity
EKN16_RS22330	COG0504	CTP synthase activity
EKN16_RS22335	COG3343	RNA polymerase activity
EKN16_RS22340	COG1404	Belongs to the peptidase S8 family
EKN16_RS22345	COG0018	arginyl-trna synthetase
EKN16_RS22365	COG0010	Belongs to the arginase family
EKN16_RS22370	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EKN16_RS22375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKN16_RS22380	COG1132	(ABC) transporter
EKN16_RS22385	COG1132	(ABC) transporter
EKN16_RS22410	COG0791	NLP P60 protein
EKN16_RS22420	COG1201	RNA secondary structure unwinding
EKN16_RS22435	COG0738	Major facilitator superfamily
EKN16_RS22450	COG2226	methyltransferase
EKN16_RS22460	COG1876	peptidase activity
EKN16_RS22470	COG0477	Major facilitator Superfamily
EKN16_RS22480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EKN16_RS22490	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EKN16_RS22495	COG0840	transmembrane signaling receptor activity
EKN16_RS22505	COG0708	Exodeoxyribonuclease III
EKN16_RS22515	COG0488	(ABC) transporter
EKN16_RS22520	COG2267	carboxylic ester hydrolase activity
EKN16_RS22530	COG0393	Putative heavy-metal-binding
EKN16_RS22555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EKN16_RS22565	COG2911	Protein conserved in bacteria
EKN16_RS22565	COG1361	Conserved repeat domain
EKN16_RS22565	COG3266	domain, Protein
EKN16_RS22585	COG3227	Zinc metalloprotease (Elastase)
EKN16_RS22590	COG1361	Conserved repeat domain
EKN16_RS22600	COG0395	ABC-type sugar transport system, permease component
EKN16_RS22605	COG4209	transmembrane transport
EKN16_RS22610	COG1472	Belongs to the glycosyl hydrolase 3 family
EKN16_RS22625	COG0667	Aldo Keto reductase
EKN16_RS22640	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS22660	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EKN16_RS22670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS22675	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EKN16_RS22685	COG2207	Transcriptional regulator
EKN16_RS22685	COG4753	response regulator
EKN16_RS22690	COG3275	phosphorelay sensor kinase activity
EKN16_RS22695	COG0395	ABC-type sugar transport system, permease component
EKN16_RS22700	COG4209	transmembrane transport
EKN16_RS22760	COG1595	DNA-templated transcription, initiation
EKN16_RS22780	COG0423	glycine-tRNA ligase activity
EKN16_RS22840	COG0653	protein targeting
EKN16_RS22855	COG4978	Transcriptional regulator
EKN16_RS22855	COG0789	Transcriptional regulator
EKN16_RS22860	COG1116	anion transmembrane transporter activity
EKN16_RS22865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EKN16_RS22870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EKN16_RS22880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EKN16_RS22895	COG0529	Catalyzes the synthesis of activated sulfate
EKN16_RS22900	COG5566	PFAM Mor transcription activator
EKN16_RS22925	COG2199	diguanylate cyclase activity
EKN16_RS22925	COG2202	Pas domain
EKN16_RS22925	COG2200	EAL domain
EKN16_RS22930	COG2154	pterin-4-alpha-carbinolamine dehydratase
EKN16_RS22940	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EKN16_RS22945	COG1360	Flagellar Motor Protein
EKN16_RS22950	COG1187	pseudouridine synthase activity
EKN16_RS22960	COG5002	protein histidine kinase activity
EKN16_RS22965	COG0590	tRNA wobble adenosine to inosine editing
EKN16_RS23000	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EKN16_RS23020	COG0517	IMP dehydrogenase activity
EKN16_RS23020	COG0516	GMP reductase activity
EKN16_RS23055	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EKN16_RS23060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EKN16_RS23065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EKN16_RS23070	COG1396	sequence-specific DNA binding
EKN16_RS23075	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EKN16_RS23080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EKN16_RS23085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EKN16_RS23090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EKN16_RS23095	COG0512	Glutamine amidotransferase of anthranilate synthase
EKN16_RS23100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKN16_RS23105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EKN16_RS23110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EKN16_RS23115	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EKN16_RS23120	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EKN16_RS23125	COG0157	Belongs to the NadC ModD family
EKN16_RS23130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EKN16_RS23135	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EKN16_RS23140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKN16_RS23155	COG0515	serine threonine protein kinase
EKN16_RS23155	COG2815	serine threonine protein kinase
EKN16_RS23160	COG2304	oxidoreductase activity
EKN16_RS23175	COG2208	phosphoserine phosphatase activity
EKN16_RS23180	COG1098	S1 RNA binding domain
EKN16_RS23200	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EKN16_RS23205	COG0776	regulation of translation
EKN16_RS23210	COG3956	TIGRFAM MazG family protein
EKN16_RS23215	COG2244	polysaccharide biosynthetic process
EKN16_RS23220	COG2002	toxin-antitoxin pair type II binding
EKN16_RS23225	COG2706	6-phosphogluconolactonase activity
EKN16_RS23230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EKN16_RS23235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EKN16_RS23255	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EKN16_RS23260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EKN16_RS23265	COG2088	sporulation resulting in formation of a cellular spore
EKN16_RS23270	COG0251	oxidation-reduction process
EKN16_RS23275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKN16_RS23280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EKN16_RS23290	COG4466	Protein conserved in bacteria
EKN16_RS23300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EKN16_RS23310	COG3583	domain protein
EKN16_RS23310	COG3584	3D domain protein
EKN16_RS23315	COG0084	hydrolase, TatD family'
EKN16_RS23320	COG1078	dGTPase activity
EKN16_RS23325	COG2002	toxin-antitoxin pair type II binding
EKN16_RS23330	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EKN16_RS23335	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EKN16_RS23345	COG4467	Involved in initiation control of chromosome replication
EKN16_RS23350	COG1774	PSP1 C-terminal conserved region
EKN16_RS23355	COG0470	DNA polymerase III
EKN16_RS23360	COG1728	Protein conserved in bacteria
EKN16_RS23365	COG3870	Protein conserved in bacteria
EKN16_RS23370	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EKN16_RS23375	COG1982	Orn Lys Arg decarboxylase major
EKN16_RS23410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EKN16_RS23410	COG2199	diguanylate cyclase activity
EKN16_RS23415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKN16_RS23425	COG0187	DNA topoisomerase II activity
EKN16_RS23440	COG2501	S4 domain
EKN16_RS23445	COG0592	DNA-directed DNA polymerase activity
EKN16_RS23450	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EKN16_RS23455	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EKN16_RS23460	COG0594	ribonuclease P activity
EKN16_RS23465	COG0706	membrane insertase activity
EKN16_RS23470	COG1847	R3H domain protein
EKN16_RS23475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EKN16_RS23480	COG0445	tRNA wobble uridine modification
EKN16_RS23490	COG1475	DNA binding
EKN16_RS23495	COG1192	Involved in chromosome partitioning
EKN16_RS23500	COG1475	DNA binding
EKN16_RS23505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKN16_RS23525	COG4481	Protein conserved in bacteria
EKN16_RS23540	COG0360	Binds together with S18 to 16S ribosomal RNA
EKN16_RS23545	COG0629	single-stranded DNA binding
EKN16_RS23550	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EKN16_RS23560	COG1316	TRANSCRIPTIONal
EKN16_RS23570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EKN16_RS23580	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EKN16_RS23585	COG0359	binds to the 23S rRNA
EKN16_RS23590	COG0305	Participates in initiation and elongation during chromosome replication
EKN16_RS23595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EKN16_RS23610	COG0745	RESPONSE REGULATOR receiver
EKN16_RS23615	COG5002	protein histidine kinase activity
EKN16_RS23630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EKN16_RS23640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKN16_RS23655	COG0194	GDP metabolic process
EKN16_RS23660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EKN16_RS23670	COG3279	Response regulator of the LytR AlgR family
EKN16_RS23675	COG0745	RESPONSE REGULATOR receiver
EKN16_RS23675	COG2972	Histidine kinase
EKN16_RS23690	COG0028	Belongs to the TPP enzyme family
EKN16_RS23705	COG1131	(ABC) transporter
EKN16_RS23715	COG0697	spore germination
EKN16_RS23725	COG1132	(ABC) transporter
EKN16_RS23730	COG1132	(ABC) transporter
EKN16_RS23735	COG1115	amino acid carrier protein
EKN16_RS23740	COG0456	acetyltransferase
EKN16_RS23770	COG1131	(ABC) transporter
EKN16_RS23775	COG2197	response regulator
EKN16_RS23780	COG2824	Alkylphosphonate utilization operon protein PhnA
EKN16_RS23800	COG1361	Conserved repeat domain
EKN16_RS23825	COG0601	transmembrane transport
EKN16_RS23830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKN16_RS23835	COG0747	negative chemotaxis
EKN16_RS23840	COG0444	Belongs to the ABC transporter superfamily
EKN16_RS23845	COG4608	Belongs to the ABC transporter superfamily
EKN16_RS23855	COG2814	Major facilitator Superfamily
EKN16_RS23865	COG2378	regulation of single-species biofilm formation
EKN16_RS23875	COG1673	EVE domain
EKN16_RS23885	COG1126	abc transporter atp-binding protein
EKN16_RS23895	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EKN16_RS23900	COG0720	synthase
EKN16_RS23910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EKN16_RS23915	COG1733	regulation of RNA biosynthetic process
EKN16_RS23925	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EKN16_RS23965	COG2207	Transcriptional regulator
EKN16_RS23970	COG1653	transport
EKN16_RS23975	COG4209	transmembrane transport
EKN16_RS23980	COG0395	ABC-type sugar transport system, permease component
EKN16_RS24010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKN16_RS24015	COG0805	protein transport
EKN16_RS24025	COG1473	amidohydrolase
EKN16_RS24040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EKN16_RS24045	COG0251	oxidation-reduction process
EKN16_RS24065	COG0673	inositol 2-dehydrogenase activity
EKN16_RS24075	COG1175	transmembrane transport
EKN16_RS24080	COG0395	ABC-type sugar transport system, permease component
EKN16_RS24085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKN16_RS24095	COG0673	inositol 2-dehydrogenase activity
EKN16_RS24110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EKN16_RS24120	COG0574	Belongs to the PEP-utilizing enzyme family
EKN16_RS24120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKN16_RS24125	COG0517	IMP dehydrogenase activity
EKN16_RS24130	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EKN16_RS24145	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EKN16_RS24155	COG1653	transport
EKN16_RS24160	COG2207	Transcriptional regulator
EKN16_RS24170	COG1175	transmembrane transport
EKN16_RS24175	COG0395	ABC-type sugar transport system, permease component
EKN16_RS24200	COG2207	Transcriptional regulator
EKN16_RS24210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKN16_RS24215	COG0805	protein transport
EKN16_RS24220	COG1653	transport
EKN16_RS24225	COG4209	transmembrane transport
EKN16_RS24230	COG0395	ABC-type sugar transport system, permease component
EKN16_RS24235	COG1874	Beta-galactosidase
EKN16_RS24240	COG5434	Belongs to the glycosyl hydrolase 28 family
EKN16_RS24280	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS24290	COG3386	PFAM SMP-30 Gluconolaconase
EKN16_RS24300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKN16_RS24310	COG1252	NADH dehydrogenase
EKN16_RS24320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKN16_RS24335	COG1309	transcriptional regulator
EKN16_RS24350	COG0697	spore germination
EKN16_RS24365	COG0789	Transcriptional regulator
EKN16_RS24380	COG2814	Major facilitator Superfamily
EKN16_RS24435	COG0492	ferredoxin-NADP+ reductase activity
EKN16_RS24470	COG1132	(ABC) transporter
EKN16_RS24475	COG1132	(ABC) transporter
EKN16_RS24480	COG0697	spore germination
EKN16_RS24485	COG0697	spore germination
EKN16_RS24495	COG0697	spore germination
EKN16_RS24510	COG2378	regulation of single-species biofilm formation
EKN16_RS24515	COG3708	Transcriptional regulator
EKN16_RS24550	COG1175	transmembrane transport
EKN16_RS24555	COG0745	RESPONSE REGULATOR receiver
EKN16_RS24560	COG5002	protein histidine kinase activity
EKN16_RS24565	COG3706	GGDEF domain
EKN16_RS24575	COG0406	alpha-ribazole phosphatase activity
EKN16_RS24580	COG1070	Carbohydrate kinase
EKN16_RS24585	COG1349	DNA-binding transcription factor activity
EKN16_RS24590	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKN16_RS24600	COG0583	DNA-binding transcription factor activity
EKN16_RS24605	COG1741	Belongs to the pirin family
EKN16_RS24620	COG1609	Transcriptional regulator
EKN16_RS24625	COG3459	Glycosyltransferase 36 associated
EKN16_RS24635	COG2972	Histidine kinase
EKN16_RS24640	COG2207	Transcriptional regulator
EKN16_RS24640	COG4753	response regulator
EKN16_RS24650	COG0805	protein transport
EKN16_RS24665	COG1653	transport
EKN16_RS24670	COG1653	transport
EKN16_RS24675	COG4209	transmembrane transport
EKN16_RS24680	COG0395	ABC-type sugar transport system, permease component
EKN16_RS24690	COG3119	arylsulfatase activity
EKN16_RS24695	COG1082	Xylose isomerase domain protein TIM barrel
EKN16_RS24700	COG3250	beta-galactosidase activity
EKN16_RS24705	COG3119	arylsulfatase activity
EKN16_RS24705	COG3408	Glycogen debranching enzyme
EKN16_RS24715	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS24740	COG4941	Belongs to the sigma-70 factor family
EKN16_RS24750	COG1733	regulation of RNA biosynthetic process
EKN16_RS24770	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS24775	COG2972	Histidine kinase
EKN16_RS24780	COG4566	intracellular signal transduction
EKN16_RS24790	COG0395	ABC-type sugar transport system, permease component
EKN16_RS24795	COG4209	transmembrane transport
EKN16_RS24805	COG0745	RESPONSE REGULATOR receiver
EKN16_RS24810	COG2205	protein histidine kinase activity
EKN16_RS24815	COG1131	(ABC) transporter
EKN16_RS24850	COG1609	Transcriptional regulator
EKN16_RS24855	COG0383	alpha-mannosidase activity
EKN16_RS24865	COG1175	transmembrane transport
EKN16_RS24870	COG0395	ABC-type sugar transport system, permease component
EKN16_RS24885	COG0069	glutamate synthase activity
EKN16_RS24895	COG2388	GCN5-related N-acetyl-transferase
EKN16_RS24900	COG0300	oxidoreductase activity
EKN16_RS24905	COG1846	Transcriptional regulator
EKN16_RS24910	COG0346	lactoylglutathione lyase activity
EKN16_RS24915	COG0400	carboxylic ester hydrolase activity
EKN16_RS24920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EKN16_RS24925	COG3239	Fatty acid desaturase
EKN16_RS24930	COG2972	Histidine kinase
EKN16_RS24945	COG4209	transmembrane transport
EKN16_RS24950	COG0395	ABC-type sugar transport system, permease component
EKN16_RS24970	COG0673	inositol 2-dehydrogenase activity
EKN16_RS24975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EKN16_RS24980	COG0765	amino acid transport
EKN16_RS24985	COG1126	abc transporter atp-binding protein
EKN16_RS24990	COG2226	methyltransferase
EKN16_RS25005	COG2814	Major facilitator Superfamily
EKN16_RS25030	COG3384	dioxygenase
EKN16_RS25035	COG1278	Cold shock
EKN16_RS25080	COG2814	Major facilitator Superfamily
EKN16_RS25085	COG0622	Phosphoesterase
EKN16_RS25095	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EKN16_RS25100	COG0840	transmembrane signaling receptor activity
EKN16_RS25140	COG0528	UMP kinase activity
EKN16_RS25160	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EKN16_RS25165	COG1132	(ABC) transporter
EKN16_RS25195	COG4895	conserved protein (DUF2196)
EKN16_RS25215	COG4846	Membrane protein involved in cytochrome C biogenesis
EKN16_RS25230	COG1846	Transcriptional regulator
EKN16_RS25235	COG0386	Belongs to the glutathione peroxidase family
EKN16_RS25260	COG0592	DNA-directed DNA polymerase activity
EKN16_RS25270	COG2353	YceI-like domain
EKN16_RS25285	COG1846	Transcriptional regulator
EKN16_RS25290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKN16_RS25305	COG3962	Belongs to the TPP enzyme family
EKN16_RS25310	COG1082	Xylose isomerase domain protein TIM barrel
EKN16_RS25315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS25320	COG1012	belongs to the aldehyde dehydrogenase family
EKN16_RS25325	COG0673	inositol 2-dehydrogenase activity
EKN16_RS25330	COG3718	enzyme involved in inositol metabolism
EKN16_RS25335	COG1609	Transcriptional regulator
EKN16_RS25340	COG0656	L-ascorbic acid biosynthetic process
EKN16_RS25365	COG4209	transmembrane transport
EKN16_RS25375	COG0395	ABC-type sugar transport system, permease component
EKN16_RS25390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS25395	COG1486	melibiose metabolic process
EKN16_RS25400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EKN16_RS25420	COG3119	arylsulfatase activity
EKN16_RS25430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS25435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKN16_RS25440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKN16_RS25445	COG1309	transcriptional regulator
EKN16_RS25455	COG1587	Uroporphyrinogen-III synthase
EKN16_RS25470	COG1472	Belongs to the glycosyl hydrolase 3 family
EKN16_RS25475	COG0697	spore germination
EKN16_RS25485	COG1801	Protein of unknown function DUF72
EKN16_RS25495	COG3118	belongs to the thioredoxin family
EKN16_RS25500	COG3177	Filamentation induced by cAMP protein fic
EKN16_RS25515	COG3424	synthase
EKN16_RS25525	COG0644	oxidoreductase
EKN16_RS25545	COG2309	aminopeptidase activity
EKN16_RS25560	COG2207	Transcriptional regulator
EKN16_RS25570	COG1940	carbohydrate kinase activity
EKN16_RS25580	COG4166	transmembrane transport
EKN16_RS25585	COG0601	transmembrane transport
EKN16_RS25590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKN16_RS25595	COG0444	Belongs to the ABC transporter superfamily
EKN16_RS25600	COG4608	Belongs to the ABC transporter superfamily
EKN16_RS25605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EKN16_RS25610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EKN16_RS25615	COG3142	Participates in the control of copper homeostasis
EKN16_RS25625	COG0012	GTP binding
EKN16_RS25630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EKN16_RS25635	COG2890	protein-(glutamine-N5) methyltransferase activity
EKN16_RS25650	COG2814	Major facilitator Superfamily
EKN16_RS25655	COG0009	L-threonylcarbamoyladenylate synthase
EKN16_RS25660	COG1971	Probably functions as a manganese efflux pump
EKN16_RS25670	COG0698	ribose 5-phosphate isomerase
EKN16_RS25675	COG4475	Protein of unknown function (DUF436)
EKN16_RS25685	COG2207	Transcriptional regulator
EKN16_RS25690	COG2814	Major facilitator Superfamily
EKN16_RS25700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EKN16_RS25705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EKN16_RS25720	COG0356	it plays a direct role in the translocation of protons across the membrane
EKN16_RS25730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EKN16_RS25735	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKN16_RS25740	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EKN16_RS25745	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EKN16_RS25750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EKN16_RS25755	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EKN16_RS25795	COG0672	)-iron permease
EKN16_RS25800	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKN16_RS25810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKN16_RS25815	COG0649	NAD binding
EKN16_RS25820	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EKN16_RS25825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKN16_RS25830	COG0839	Belongs to the complex I subunit 6 family
EKN16_RS25835	COG0713	ATP synthesis coupled electron transport
EKN16_RS25840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EKN16_RS25845	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKN16_RS25850	COG1007	ATP synthesis coupled electron transport
EKN16_RS25855	COG1404	Belongs to the peptidase S8 family
EKN16_RS25865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKN16_RS25870	COG2385	sporulation resulting in formation of a cellular spore
EKN16_RS25875	COG0739	heme binding
EKN16_RS25875	COG0741	lytic transglycosylase activity
EKN16_RS25875	COG1196	nuclear chromosome segregation
EKN16_RS25880	COG1609	Transcriptional regulator
EKN16_RS25890	COG4786	Flagellar basal body rod
EKN16_RS25895	COG4786	Flagellar basal body rod
EKN16_RS25910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKN16_RS25920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKN16_RS25940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKN16_RS25970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EKN16_RS25975	COG3693	PFAM glycoside hydrolase, family 10
EKN16_RS26000	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EKN16_RS26020	COG3418	PFAM FlgN family protein
EKN16_RS26025	COG1256	bacterial-type flagellum assembly
EKN16_RS26025	COG4786	Flagellar basal body rod
EKN16_RS26030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EKN16_RS26045	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EKN16_RS26050	COG0673	inositol 2-dehydrogenase activity
EKN16_RS26055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EKN16_RS26065	COG0463	Glycosyl transferase, family 2
EKN16_RS26070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EKN16_RS26085	COG1516	flagellar protein fliS
EKN16_RS26095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EKN16_RS26100	COG0463	Glycosyl transferase, family 2
EKN16_RS26105	COG1278	Cold shock
EKN16_RS26140	COG0653	protein targeting
EKN16_RS26150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKN16_RS26155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EKN16_RS26160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EKN16_RS26165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EKN16_RS26175	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EKN16_RS26180	COG0137	argininosuccinate synthase activity
EKN16_RS26185	COG0165	Argininosuccinate lyase
EKN16_RS26190	COG2720	vancomycin resistance protein
EKN16_RS26195	COG2884	Cell division ATP-binding protein ftsE
EKN16_RS26200	COG2177	Part of the ABC transporter FtsEX involved in
EKN16_RS26205	COG0739	heme binding
EKN16_RS26210	COG3409	Peptidoglycan-binding domain 1 protein
EKN16_RS26210	COG0793	Belongs to the peptidase S41A family
EKN16_RS26215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKN16_RS26230	COG0556	nucleotide-excision repair
EKN16_RS26235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EKN16_RS26240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKN16_RS26260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKN16_RS26270	COG0826	peptidase U32
EKN16_RS26295	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EKN16_RS26300	COG0210	DNA helicase
EKN16_RS26305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EKN16_RS26335	COG3880	PFAM UvrB UvrC protein
EKN16_RS26340	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EKN16_RS26345	COG0542	response to heat
EKN16_RS26355	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EKN16_RS26360	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EKN16_RS26365	COG1183	phosphatidylcholine synthase activity
EKN16_RS26375	COG4956	integral membrane protein (PIN domain superfamily)
EKN16_RS26380	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EKN16_RS26385	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EKN16_RS26390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKN16_RS26395	COG1045	serine acetyltransferase
EKN16_RS26400	COG0215	cysteine-tRNA ligase activity
EKN16_RS26405	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EKN16_RS26410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKN16_RS26415	COG3688	RNA-binding protein containing a PIN domain
EKN16_RS26425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EKN16_RS26430	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EKN16_RS26435	COG0250	Participates in transcription elongation, termination and antitermination
EKN16_RS26440	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EKN16_RS26445	COG0081	regulation of translation
EKN16_RS26450	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EKN16_RS26455	COG0222	ribosome binding
EKN16_RS26460	COG2813	Specifically methylates the guanine in position
EKN16_RS26465	COG0085	RNA polymerase activity
EKN16_RS26470	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKN16_RS26480	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EKN16_RS26485	COG0049	tRNA binding
EKN16_RS26490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKN16_RS26495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EKN16_RS26505	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EKN16_RS26510	COG0088	Forms part of the polypeptide exit tunnel
EKN16_RS26515	COG0089	rRNA binding
EKN16_RS26520	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EKN16_RS26530	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EKN16_RS26535	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EKN16_RS26540	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EKN16_RS26545	COG0255	Belongs to the universal ribosomal protein uL29 family
EKN16_RS26550	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EKN16_RS26555	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EKN16_RS26560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EKN16_RS26565	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EKN16_RS26575	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EKN16_RS26580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EKN16_RS26590	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EKN16_RS26595	COG1841	ribosomal large subunit assembly
EKN16_RS26600	COG0200	Binds to the 23S rRNA
EKN16_RS26605	COG0201	protein transport
EKN16_RS26610	COG0563	adenylate kinase activity
EKN16_RS26615	COG0024	Methionine aminopeptidase
EKN16_RS26625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EKN16_RS26630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EKN16_RS26635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EKN16_RS26640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EKN16_RS26645	COG0202	RNA polymerase activity
EKN16_RS26650	COG0203	ribosomal protein L17
EKN16_RS26655	COG0101	tRNA pseudouridine synthase activity
EKN16_RS26660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EKN16_RS26665	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EKN16_RS26675	COG2046	Belongs to the sulfate adenylyltransferase family
EKN16_RS26680	COG0860	N-Acetylmuramoyl-L-alanine amidase
EKN16_RS26685	COG0489	protein tyrosine kinase activity
EKN16_RS26700	COG0726	polysaccharide deacetylase
EKN16_RS26780	COG1120	ATPase activity
EKN16_RS26810	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EKN16_RS26820	COG1595	DNA-templated transcription, initiation
EKN16_RS26825	COG5662	AntiSigma factor
EKN16_RS26830	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EKN16_RS26840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKN16_RS26900	COG3384	dioxygenase
EKN16_RS26905	COG1733	regulation of RNA biosynthetic process
EKN16_RS26915	COG0778	Nitroreductase
EKN16_RS26930	COG1609	Transcriptional regulator
EKN16_RS26935	COG0657	acetylesterase activity
EKN16_RS26940	COG1609	Transcriptional regulator
EKN16_RS26960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS26965	COG0366	Alpha amylase catalytic
EKN16_RS26990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EKN16_RS27000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EKN16_RS27020	COG0697	spore germination
EKN16_RS27025	COG0531	amino acid
EKN16_RS27035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS27040	COG1175	transmembrane transport
EKN16_RS27045	COG0395	ABC-type sugar transport system, permease component
EKN16_RS27050	COG2972	Histidine kinase
EKN16_RS27055	COG2207	Transcriptional regulator
EKN16_RS27055	COG4753	response regulator
EKN16_RS27070	COG2207	Transcriptional regulator
EKN16_RS27070	COG4753	response regulator
EKN16_RS27080	COG1609	Transcriptional regulator
EKN16_RS27090	COG0640	Transcriptional regulator
EKN16_RS27105	COG2207	Transcriptional regulator
EKN16_RS27110	COG3275	phosphorelay sensor kinase activity
EKN16_RS27115	COG1653	transport
EKN16_RS27120	COG4209	transmembrane transport
EKN16_RS27125	COG0395	ABC-type sugar transport system, permease component
EKN16_RS27135	COG3250	beta-galactosidase activity
EKN16_RS27150	COG1733	regulation of RNA biosynthetic process
EKN16_RS27160	COG2378	regulation of single-species biofilm formation
EKN16_RS27165	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS27190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EKN16_RS27195	COG1959	2 iron, 2 sulfur cluster binding
EKN16_RS27200	COG2910	NAD(P)H-binding
EKN16_RS27210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EKN16_RS27220	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EKN16_RS27250	COG1271	oxidase subunit
EKN16_RS27255	COG1294	oxidase, subunit
EKN16_RS27260	COG4988	ABC transporter
EKN16_RS27265	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EKN16_RS27270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKN16_RS27280	COG2197	response regulator
EKN16_RS27285	COG4585	Histidine kinase
EKN16_RS27295	COG0589	response to stress
EKN16_RS27315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKN16_RS27320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKN16_RS27330	COG0656	L-ascorbic acid biosynthetic process
EKN16_RS27335	COG2814	Major facilitator Superfamily
EKN16_RS27340	COG1733	regulation of RNA biosynthetic process
EKN16_RS27355	COG2195	Cleaves the N-terminal amino acid of tripeptides
EKN16_RS27360	COG0725	ABC transporter, periplasmic molybdate-binding protein
EKN16_RS27365	COG4149	molybdate abc transporter
EKN16_RS27370	COG1910	domain protein
EKN16_RS27380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKN16_RS27390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EKN16_RS27390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EKN16_RS27390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKN16_RS27400	COG1105	Belongs to the carbohydrate kinase PfkB family
EKN16_RS27405	COG1349	DNA-binding transcription factor activity
EKN16_RS27410	COG5002	protein histidine kinase activity
EKN16_RS27435	COG1846	Transcriptional regulator
EKN16_RS27450	COG3708	Transcriptional regulator
EKN16_RS27450	COG2207	Transcriptional regulator
EKN16_RS27510	COG0300	oxidoreductase activity
EKN16_RS27525	COG2514	catechol 2,3-dioxygenase activity
EKN16_RS27540	COG1361	Conserved repeat domain
EKN16_RS27540	COG2911	Protein conserved in bacteria
EKN16_RS27540	COG3266	domain, Protein
EKN16_RS27550	COG1940	carbohydrate kinase activity
EKN16_RS27560	COG2201	protein-glutamate methylesterase activity
EKN16_RS27565	COG1621	beta-fructofuranosidase activity
EKN16_RS27580	COG1175	transmembrane transport
EKN16_RS27585	COG0395	ABC-type sugar transport system, permease component
EKN16_RS27605	COG1175	transmembrane transport
EKN16_RS27610	COG0395	ABC-type sugar transport system, permease component
EKN16_RS27620	COG1621	beta-fructofuranosidase activity
EKN16_RS27635	COG1902	pentaerythritol trinitrate reductase activity
EKN16_RS27660	COG4209	transmembrane transport
EKN16_RS27665	COG0395	ABC-type sugar transport system, permease component
EKN16_RS27685	COG0673	inositol 2-dehydrogenase activity
EKN16_RS27710	COG1361	Conserved repeat domain
EKN16_RS27715	COG1653	transport
EKN16_RS27720	COG1175	transmembrane transport
EKN16_RS27725	COG0395	ABC-type sugar transport system, permease component
EKN16_RS27730	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS27745	COG0251	oxidation-reduction process
EKN16_RS27765	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS27775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EKN16_RS27780	COG0022	dehydrogenase e1 component
EKN16_RS27780	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKN16_RS27785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EKN16_RS27805	COG0456	acetyltransferase
EKN16_RS27815	COG1653	transport
EKN16_RS27830	COG1175	transmembrane transport
EKN16_RS27835	COG0395	ABC-type sugar transport system, permease component
EKN16_RS27845	COG0673	inositol 2-dehydrogenase activity
EKN16_RS27850	COG2201	protein-glutamate methylesterase activity
EKN16_RS27855	COG3275	phosphorelay sensor kinase activity
EKN16_RS27860	COG4209	transmembrane transport
EKN16_RS27865	COG0395	ABC-type sugar transport system, permease component
EKN16_RS27870	COG2972	Histidine kinase
EKN16_RS27875	COG2197	response regulator
EKN16_RS27890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EKN16_RS27910	COG0131	Imidazoleglycerol-phosphate dehydratase
EKN16_RS27920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EKN16_RS27935	COG1595	DNA-templated transcription, initiation
EKN16_RS27960	COG1737	Transcriptional regulator
EKN16_RS27965	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EKN16_RS27990	COG0395	ABC-type sugar transport system, permease component
EKN16_RS28000	COG2267	carboxylic ester hydrolase activity
EKN16_RS28025	COG3848	Pyruvate phosphate dikinase
EKN16_RS28025	COG0574	Belongs to the PEP-utilizing enzyme family
EKN16_RS28035	COG1695	Transcriptional regulator
EKN16_RS28050	COG0110	maltose O-acetyltransferase activity
EKN16_RS28070	COG2610	gluconate transmembrane transporter activity
EKN16_RS28080	COG2318	DinB family
EKN16_RS28085	COG2318	DinB family
EKN16_RS28135	COG0456	acetyltransferase
EKN16_RS28140	COG0546	phosphoglycolate phosphatase activity
EKN16_RS28155	COG0789	Transcriptional regulator
EKN16_RS28185	COG3858	chitin binding
EKN16_RS28195	COG2814	Major facilitator Superfamily
EKN16_RS28200	COG1214	PFAM Peptidase M22, glycoprotease
EKN16_RS28200	COG0456	acetyltransferase
EKN16_RS28215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKN16_RS28230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKN16_RS28230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKN16_RS28275	COG5002	protein histidine kinase activity
EKN16_RS28280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EKN16_RS28325	COG1132	(ABC) transporter
EKN16_RS28330	COG1132	(ABC) transporter
EKN16_RS28345	COG0656	L-ascorbic acid biosynthetic process
EKN16_RS28395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKN16_RS28410	COG4585	Histidine kinase
EKN16_RS28415	COG2197	response regulator
EKN16_RS28420	COG2409	Drug exporters of the RND superfamily
EKN16_RS28435	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS28435	COG4977	sequence-specific DNA binding
EKN16_RS28475	COG2814	Major facilitator Superfamily
EKN16_RS28490	COG2720	vancomycin resistance protein
EKN16_RS28530	COG0789	Transcriptional regulator
EKN16_RS28535	COG2814	Major facilitator Superfamily
EKN16_RS28565	COG3858	chitin binding
EKN16_RS28605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKN16_RS28660	COG1940	carbohydrate kinase activity
EKN16_RS28665	COG0667	Aldo Keto reductase
EKN16_RS28675	COG1175	transmembrane transport
EKN16_RS28680	COG0395	ABC-type sugar transport system, permease component
EKN16_RS28700	COG3962	Belongs to the TPP enzyme family
EKN16_RS28705	COG3718	enzyme involved in inositol metabolism
EKN16_RS28710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS28715	COG1012	belongs to the aldehyde dehydrogenase family
EKN16_RS28760	COG1609	Transcriptional regulator
EKN16_RS28765	COG0657	acetylesterase activity
EKN16_RS28765	COG2755	lipolytic protein G-D-S-L family
EKN16_RS28770	COG1609	Transcriptional regulator
EKN16_RS28775	COG4209	transmembrane transport
EKN16_RS28780	COG0395	ABC-type sugar transport system, permease component
EKN16_RS28785	COG1653	transport
EKN16_RS28825	COG4282	regulation of fungal-type cell wall biogenesis
EKN16_RS28830	COG0598	Magnesium transport protein CorA
EKN16_RS28840	COG2226	methyltransferase
EKN16_RS28850	COG2059	Chromate
EKN16_RS28860	COG1176	ABC-type spermidine putrescine transport system, permease component I
EKN16_RS28865	COG1177	transmembrane transport
EKN16_RS28870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EKN16_RS28880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKN16_RS28890	COG0436	Aminotransferase
EKN16_RS28910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EKN16_RS28930	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS28940	COG1733	regulation of RNA biosynthetic process
EKN16_RS28970	COG1349	DNA-binding transcription factor activity
EKN16_RS28975	COG1879	ABC-type sugar transport system periplasmic component
EKN16_RS28980	COG1129	ABC transporter
EKN16_RS28985	COG1172	Belongs to the binding-protein-dependent transport system permease family
EKN16_RS28995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EKN16_RS29000	COG1070	Carbohydrate kinase
EKN16_RS29005	COG3347	Dehydrogenase
EKN16_RS29005	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS29010	COG1461	Dihydroxyacetone kinase
EKN16_RS29015	COG0698	ribose 5-phosphate isomerase
EKN16_RS29020	COG2376	Dihydroxyacetone kinase
EKN16_RS29030	COG2268	Band 7 protein
EKN16_RS29045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKN16_RS29065	COG0671	phosphoesterase, PA-phosphatase related
EKN16_RS29075	COG1929	Belongs to the glycerate kinase type-1 family
EKN16_RS29090	COG1733	regulation of RNA biosynthetic process
EKN16_RS29095	COG0667	Aldo Keto reductase
EKN16_RS29110	COG1793	dna ligase
EKN16_RS29110	COG3285	dna ligase
EKN16_RS29120	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EKN16_RS29135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKN16_RS29140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EKN16_RS29145	COG0802	atpase or kinase
EKN16_RS29150	COG1214	PFAM Peptidase M22, glycoprotease
EKN16_RS29155	COG0456	acetyltransferase
EKN16_RS29160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EKN16_RS29165	COG1309	transcriptional regulator
EKN16_RS29170	COG2076	Multidrug Resistance protein
EKN16_RS29175	COG2076	Multidrug Resistance protein
EKN16_RS29180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKN16_RS29190	COG0488	(ABC) transporter
EKN16_RS29195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EKN16_RS29200	COG0315	cyclic pyranopterin monophosphate synthase activity
EKN16_RS29205	COG0521	Mo-molybdopterin cofactor biosynthetic process
EKN16_RS29215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKN16_RS29220	COG0805	protein transport
EKN16_RS29225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EKN16_RS29230	COG0459	protein refolding
EKN16_RS29250	COG0745	RESPONSE REGULATOR receiver
EKN16_RS29250	COG2972	Histidine kinase
EKN16_RS29260	COG3275	phosphorelay sensor kinase activity
EKN16_RS29265	COG4753	response regulator
EKN16_RS29265	COG2207	Transcriptional regulator
EKN16_RS29275	COG4209	transmembrane transport
EKN16_RS29280	COG0395	ABC-type sugar transport system, permease component
EKN16_RS29315	COG1361	Conserved repeat domain
EKN16_RS29320	COG2972	Histidine kinase
EKN16_RS29325	COG4753	response regulator
EKN16_RS29325	COG2207	Transcriptional regulator
EKN16_RS29325	COG2207	Transcriptional regulator
EKN16_RS29325	COG4753	response regulator
EKN16_RS29335	COG1175	transmembrane transport
EKN16_RS29340	COG0395	ABC-type sugar transport system, permease component
EKN16_RS29345	COG0673	inositol 2-dehydrogenase activity
EKN16_RS29370	COG1309	transcriptional regulator
EKN16_RS29385	COG0523	cobalamin synthesis protein
EKN16_RS29390	COG0523	cobalamin synthesis protein
EKN16_RS29400	COG2378	regulation of single-species biofilm formation
EKN16_RS29405	COG0673	inositol 2-dehydrogenase activity
EKN16_RS29415	COG3832	glyoxalase III activity
EKN16_RS29420	COG0640	Transcriptional regulator
EKN16_RS29425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKN16_RS29435	COG0477	Major facilitator Superfamily
EKN16_RS29445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKN16_RS29465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKN16_RS29470	COG0745	RESPONSE REGULATOR receiver
EKN16_RS29480	COG0835	chemotaxis
EKN16_RS29485	COG0643	Histidine kinase
EKN16_RS29485	COG2198	Histidine kinase
EKN16_RS29490	COG3300	MHYT domain
EKN16_RS29490	COG5001	Diguanylate cyclase
EKN16_RS29500	COG5002	protein histidine kinase activity
EKN16_RS29500	COG0784	Response regulator, receiver
EKN16_RS29500	COG2205	protein histidine kinase activity
EKN16_RS29505	COG0673	inositol 2-dehydrogenase activity
EKN16_RS29525	COG0251	oxidation-reduction process
EKN16_RS29540	COG0179	Fumarylacetoacetate (FAA) hydrolase
EKN16_RS29555	COG1609	Transcriptional regulator
EKN16_RS29570	COG0366	Alpha amylase catalytic
EKN16_RS29575	COG2182	Extracellular solute-binding protein
EKN16_RS29585	COG0395	ABC-type sugar transport system, permease component
EKN16_RS29610	COG2801	Transposase and inactivated derivatives
EKN16_RS29630	COG1653	transport
EKN16_RS29635	COG4209	transmembrane transport
EKN16_RS29640	COG0395	ABC-type sugar transport system, permease component
EKN16_RS29655	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EKN16_RS29660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKN16_RS29665	COG0864	Transcriptional regulator
EKN16_RS29670	COG2337	Toxic component of a toxin-antitoxin (TA) module
EKN16_RS29695	COG4869	propanediol catabolic process
EKN16_RS29705	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EKN16_RS29730	COG4819	ethanolamine utilization protein
EKN16_RS29735	COG4303	Ethanolamine ammonia lyase large subunit
EKN16_RS29780	COG5522	Integral membrane protein (intg_mem_TP0381)
EKN16_RS29795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EKN16_RS29800	COG0583	DNA-binding transcription factor activity
EKN16_RS29805	COG1312	Catalyzes the dehydration of D-mannonate
EKN16_RS29860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKN16_RS29865	COG1845	cytochrome c oxidase, subunit III
EKN16_RS29890	COG0180	Tryptophanyl-tRNA synthetase
EKN16_RS29895	COG1595	DNA-templated transcription, initiation
EKN16_RS29915	COG1131	(ABC) transporter
EKN16_RS29920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EKN16_RS29930	COG0745	RESPONSE REGULATOR receiver
EKN16_RS29945	COG2205	protein histidine kinase activity
EKN16_RS29965	COG1131	(ABC) transporter
EKN16_RS29970	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKN16_RS29975	COG0154	amidase activity
EKN16_RS29980	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKN16_RS29990	COG0735	belongs to the Fur family
EKN16_RS30120	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS30130	COG3275	phosphorelay sensor kinase activity
EKN16_RS30135	COG2207	Transcriptional regulator
EKN16_RS30140	COG4209	transmembrane transport
EKN16_RS30145	COG0395	ABC-type sugar transport system, permease component
EKN16_RS30150	COG1653	transport
EKN16_RS30160	COG1842	Phage shock protein A
EKN16_RS30165	COG1983	PspC domain protein
EKN16_RS30170	COG1842	Phage shock protein A
EKN16_RS30175	COG4585	Histidine kinase
EKN16_RS30180	COG2197	response regulator
EKN16_RS30185	COG1763	Mo-molybdopterin cofactor biosynthetic process
EKN16_RS30190	COG0303	'Molybdopterin
EKN16_RS30205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EKN16_RS30215	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EKN16_RS30220	COG1609	Transcriptional regulator
EKN16_RS30225	COG0673	inositol 2-dehydrogenase activity
EKN16_RS30235	COG0673	inositol 2-dehydrogenase activity
EKN16_RS30245	COG0569	domain protein
EKN16_RS30250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKN16_RS30275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKN16_RS30285	COG0640	Transcriptional regulator
EKN16_RS30290	COG2814	Major facilitator Superfamily
EKN16_RS30340	COG2186	Transcriptional regulator
EKN16_RS30345	COG0277	FAD linked oxidase domain protein
EKN16_RS30350	COG0247	lactate metabolic process
EKN16_RS30355	COG2814	Major facilitator Superfamily
EKN16_RS30370	COG0739	heme binding
EKN16_RS30375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EKN16_RS30380	COG4470	Protein conserved in bacteria
EKN16_RS30385	COG1132	(ABC) transporter
EKN16_RS30390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKN16_RS30395	COG3314	Sporulation integral membrane protein YlbJ
EKN16_RS30400	COG2346	COG2346, Truncated hemoglobins
EKN16_RS30425	COG0105	UTP biosynthetic process
EKN16_RS30430	COG0778	Nitroreductase
EKN16_RS30485	COG1090	epimerase
EKN16_RS30500	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EKN16_RS30505	COG0788	formyltetrahydrofolate deformylase activity
EKN16_RS30515	COG3123	guanosine phosphorylase activity
EKN16_RS30525	COG0166	Belongs to the GPI family
EKN16_RS30530	COG1739	Uncharacterized protein family UPF0029
EKN16_RS30535	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EKN16_RS30540	COG4208	sulfate ABC transporter
EKN16_RS30545	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EKN16_RS30550	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EKN16_RS30565	COG0561	phosphatase activity
EKN16_RS30575	COG0793	Belongs to the peptidase S41A family
EKN16_RS30575	COG3409	Peptidoglycan-binding domain 1 protein
EKN16_RS30580	COG0516	GMP reductase activity
EKN16_RS30580	COG0517	IMP dehydrogenase activity
EKN16_RS30595	COG0640	Transcriptional regulator
EKN16_RS30605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKN16_RS30610	COG0564	pseudouridine synthase activity
EKN16_RS30620	COG4977	sequence-specific DNA binding
EKN16_RS30625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKN16_RS30635	COG0667	Aldo Keto reductase
EKN16_RS30645	COG2076	Multidrug Resistance protein
EKN16_RS30655	COG0463	Glycosyl transferase, family 2
EKN16_RS30665	COG1482	cell wall glycoprotein biosynthetic process
EKN16_RS30670	COG0346	lactoylglutathione lyase activity
EKN16_RS30675	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EKN16_RS30680	COG1242	4 iron, 4 sulfur cluster binding
EKN16_RS30690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EKN16_RS30700	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS30700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKN16_RS30705	COG1215	transferase activity, transferring glycosyl groups
EKN16_RS30715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EKN16_RS30720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EKN16_RS30735	COG0028	Belongs to the TPP enzyme family
EKN16_RS30740	COG0440	acetolactate synthase activity
EKN16_RS30745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EKN16_RS30750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKN16_RS30760	COG2197	response regulator
EKN16_RS30770	COG0473	3-isopropylmalate dehydrogenase activity
EKN16_RS30785	COG1191	sigma factor activity
EKN16_RS30800	COG3852	Histidine kinase
EKN16_RS30805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EKN16_RS30815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EKN16_RS30820	COG1012	belongs to the aldehyde dehydrogenase family
EKN16_RS30820	COG1454	alcohol dehydrogenase
EKN16_RS30840	COG3594	Acyltransferase
EKN16_RS30865	COG2116	formate transmembrane transporter activity
EKN16_RS30870	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EKN16_RS30875	COG1522	sequence-specific DNA binding
EKN16_RS30890	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EKN16_RS30895	COG1522	sequence-specific DNA binding
EKN16_RS30900	COG0243	molybdopterin cofactor binding
EKN16_RS30905	COG0371	Dehydrogenase
EKN16_RS30910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EKN16_RS30915	COG0697	spore germination
EKN16_RS30920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EKN16_RS30945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKN16_RS30955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EKN16_RS30985	COG3850	Histidine kinase
EKN16_RS30985	COG5002	protein histidine kinase activity
EKN16_RS30990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKN16_RS31000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EKN16_RS31010	COG1012	belongs to the aldehyde dehydrogenase family
EKN16_RS31020	COG4753	response regulator
EKN16_RS31020	COG2207	Transcriptional regulator
EKN16_RS31025	COG2972	Histidine kinase
EKN16_RS31035	COG1175	transmembrane transport
EKN16_RS31040	COG0395	ABC-type sugar transport system, permease component
EKN16_RS31050	COG4948	Mandelate Racemase Muconate Lactonizing
EKN16_RS31055	COG0824	Thioesterase
EKN16_RS31060	COG3711	transcriptional antiterminator
EKN16_RS31065	COG2190	(PTS) system
EKN16_RS31070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKN16_RS31070	COG1263	PTS System
EKN16_RS31075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKN16_RS31090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKN16_RS31100	COG1033	growth of symbiont in host cell
EKN16_RS31100	COG2409	Drug exporters of the RND superfamily
EKN16_RS31105	COG1309	transcriptional regulator
EKN16_RS31125	COG1595	DNA-templated transcription, initiation
EKN16_RS31135	COG1131	(ABC) transporter
EKN16_RS31140	COG3300	MHYT domain
EKN16_RS31140	COG5001	Diguanylate cyclase
EKN16_RS31150	COG1988	membrane-bound metal-dependent
EKN16_RS31155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKN16_RS31160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKN16_RS31170	COG4585	Histidine kinase
EKN16_RS31185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EKN16_RS31195	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EKN16_RS31200	COG1028	Short-chain dehydrogenase reductase Sdr
EKN16_RS31215	COG1193	negative regulation of DNA recombination
EKN16_RS31220	COG3766	membrane
EKN16_RS31230	COG0477	Major facilitator Superfamily
EKN16_RS31235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EKN16_RS31240	COG5337	Spore coat protein CotH
EKN16_RS31270	COG1522	sequence-specific DNA binding
EKN16_RS31275	COG0436	Aminotransferase
EKN16_RS31285	COG2096	Adenosyltransferase
EKN16_RS31290	COG0564	pseudouridine synthase activity
EKN16_RS31295	COG1393	Belongs to the ArsC family
EKN16_RS31300	COG0436	Aminotransferase
EKN16_RS31305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKN16_RS31315	COG4509	Sortase family
EKN16_RS31345	COG0673	inositol 2-dehydrogenase activity
EKN16_RS31355	COG0673	inositol 2-dehydrogenase activity
EKN16_RS31410	COG0395	ABC-type sugar transport system, permease component
EKN16_RS31425	COG1175	transmembrane transport
EKN16_RS31430	COG0395	ABC-type sugar transport system, permease component
EKN16_RS31475	COG0300	oxidoreductase activity
EKN16_RS31480	COG0513	Belongs to the DEAD box helicase family
EKN16_RS31485	COG1361	Conserved repeat domain
EKN16_RS31490	COG1131	(ABC) transporter
EKN16_RS31495	COG4473	ABC transporter
EKN16_RS31500	COG2197	response regulator
EKN16_RS31505	COG0840	transmembrane signaling receptor activity
EKN16_RS31520	COG2182	Extracellular solute-binding protein
EKN16_RS31525	COG0436	Aminotransferase
EKN16_RS31545	COG2188	Transcriptional regulator
EKN16_RS31550	COG0363	glucosamine-6-phosphate deaminase activity
EKN16_RS31570	COG0438	transferase activity, transferring glycosyl groups
EKN16_RS31585	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EKN16_RS31590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EKN16_RS31595	COG0352	thiamine-phosphate diphosphorylase activity
EKN16_RS31600	COG2022	thiamine diphosphate biosynthetic process
EKN16_RS31605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EKN16_RS31610	COG0352	thiamine-phosphate diphosphorylase activity
EKN16_RS31610	COG0351	phosphomethylpyrimidine kinase
EKN16_RS31615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKN16_RS31620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKN16_RS31625	COG1132	(ABC) transporter
EKN16_RS31655	COG0673	inositol 2-dehydrogenase activity
EKN16_RS31670	COG4641	Protein conserved in bacteria
EKN16_RS31670	COG1388	LysM domain
EKN16_RS31710	COG4753	response regulator
EKN16_RS31710	COG2207	Transcriptional regulator
EKN16_RS31715	COG1653	transport
EKN16_RS31725	COG4209	transmembrane transport
EKN16_RS31730	COG0395	ABC-type sugar transport system, permease component
EKN16_RS31745	COG2207	Transcriptional regulator
EKN16_RS31745	COG4753	response regulator
EKN16_RS31745	COG2207	Transcriptional regulator
EKN16_RS31745	COG4753	response regulator
EKN16_RS31750	COG2814	Major facilitator Superfamily
EKN16_RS31755	COG2207	Transcriptional regulator
EKN16_RS31755	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS31765	COG1609	Transcriptional regulator
EKN16_RS31770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS31785	COG0395	ABC-type sugar transport system, permease component
EKN16_RS31810	COG4209	transmembrane transport
EKN16_RS31815	COG0395	ABC-type sugar transport system, permease component
EKN16_RS31830	COG2207	Transcriptional regulator
EKN16_RS31830	COG4753	response regulator
EKN16_RS31830	COG2207	Transcriptional regulator
EKN16_RS31830	COG4753	response regulator
EKN16_RS31835	COG2814	Major facilitator Superfamily
EKN16_RS31840	COG2207	Transcriptional regulator
EKN16_RS31840	COG1917	Cupin 2, conserved barrel domain protein
EKN16_RS31850	COG1609	Transcriptional regulator
EKN16_RS31855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKN16_RS31870	COG0395	ABC-type sugar transport system, permease component
EKN16_RS31885	COG1361	Conserved repeat domain
EKN16_RS31890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EKN16_RS31895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKN16_RS31900	COG2207	Transcriptional regulator
EKN16_RS31900	COG4753	response regulator
EKN16_RS31905	COG2972	Histidine kinase
EKN16_RS31925	COG1621	beta-fructofuranosidase activity