locus-tag	class	description
GCU45_RS00015	COG2207	Transcriptional regulator
GCU45_RS00015	COG0662	Cupin 2, conserved barrel domain protein
GCU45_RS00020	COG4209	transmembrane transport
GCU45_RS00025	COG0395	ABC-type sugar transport system, permease component
GCU45_RS00030	COG1653	transport
GCU45_RS00035	COG0753	catalase activity
GCU45_RS00040	COG1733	regulation of RNA biosynthetic process
GCU45_RS00060	COG2070	2-Nitropropane dioxygenase
GCU45_RS00060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GCU45_RS00065	COG4221	oxidoreductase activity
GCU45_RS00065	COG3321	synthase
GCU45_RS00065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCU45_RS00065	COG0300	oxidoreductase activity
GCU45_RS00070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCU45_RS00070	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS00070	COG3321	synthase
GCU45_RS00070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCU45_RS00070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCU45_RS00075	COG4221	oxidoreductase activity
GCU45_RS00075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCU45_RS00075	COG3321	synthase
GCU45_RS00075	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS00075	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS00075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCU45_RS00075	COG4221	oxidoreductase activity
GCU45_RS00075	COG3321	synthase
GCU45_RS00080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCU45_RS00090	COG0789	Transcriptional regulator
GCU45_RS00110	COG1966	Carbon starvation protein
GCU45_RS00115	COG3279	Response regulator of the LytR AlgR family
GCU45_RS00120	COG3275	phosphorelay sensor kinase activity
GCU45_RS00125	COG4533	DNA binding
GCU45_RS00135	COG4166	transmembrane transport
GCU45_RS00140	COG0601	transmembrane transport
GCU45_RS00145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU45_RS00155	COG4608	Belongs to the ABC transporter superfamily
GCU45_RS00185	COG0531	amino acid
GCU45_RS00190	COG1472	Belongs to the glycosyl hydrolase 3 family
GCU45_RS00195	COG4974	Belongs to the 'phage' integrase family
GCU45_RS00200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GCU45_RS00210	COG0154	amidase activity
GCU45_RS00220	COG0789	Transcriptional regulator
GCU45_RS00255	COG0395	ABC-type sugar transport system, permease component
GCU45_RS00260	COG1175	transmembrane transport
GCU45_RS00265	COG2207	Transcriptional regulator
GCU45_RS00270	COG2972	Histidine kinase
GCU45_RS00275	COG0778	Nitroreductase
GCU45_RS00280	COG1309	transcriptional regulator
GCU45_RS00285	COG2814	Major facilitator Superfamily
GCU45_RS00305	COG1653	transport
GCU45_RS00310	COG0395	ABC-type sugar transport system, permease component
GCU45_RS00315	COG4209	transmembrane transport
GCU45_RS00320	COG2972	Histidine kinase
GCU45_RS00330	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCU45_RS00335	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS00345	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS00395	COG2115	Belongs to the xylose isomerase family
GCU45_RS00400	COG0662	Cupin 2, conserved barrel domain protein
GCU45_RS00400	COG2207	Transcriptional regulator
GCU45_RS00405	COG0673	inositol 2-dehydrogenase activity
GCU45_RS00415	COG0395	ABC-type sugar transport system, permease component
GCU45_RS00420	COG1175	transmembrane transport
GCU45_RS00430	COG1082	Xylose isomerase domain protein TIM barrel
GCU45_RS00435	COG1063	alcohol dehydrogenase
GCU45_RS00470	COG0667	Aldo Keto reductase
GCU45_RS00475	COG2814	Major facilitator Superfamily
GCU45_RS00480	COG1309	transcriptional regulator
GCU45_RS00510	COG2197	response regulator
GCU45_RS00515	COG4585	Histidine kinase
GCU45_RS00520	COG2409	Drug exporters of the RND superfamily
GCU45_RS00545	COG1733	regulation of RNA biosynthetic process
GCU45_RS00550	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS00560	COG2197	response regulator
GCU45_RS00565	COG4585	Histidine kinase
GCU45_RS00570	COG1999	signal sequence binding
GCU45_RS00590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU45_RS00595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCU45_RS00605	COG2801	Transposase and inactivated derivatives
GCU45_RS00615	COG0604	alcohol dehydrogenase
GCU45_RS00640	COG1653	transport
GCU45_RS00645	COG0395	ABC-type sugar transport system, permease component
GCU45_RS00650	COG4209	transmembrane transport
GCU45_RS00675	COG0529	Catalyzes the synthesis of activated sulfate
GCU45_RS00685	COG0444	Belongs to the ABC transporter superfamily
GCU45_RS00690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU45_RS00695	COG0601	transmembrane transport
GCU45_RS00700	COG0747	negative chemotaxis
GCU45_RS00715	COG5002	protein histidine kinase activity
GCU45_RS00720	COG0745	RESPONSE REGULATOR receiver
GCU45_RS00745	COG0494	nUDIX hydrolase
GCU45_RS00780	COG1940	carbohydrate kinase activity
GCU45_RS00785	COG1609	Transcriptional regulator
GCU45_RS00790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCU45_RS00835	COG0028	Belongs to the TPP enzyme family
GCU45_RS00835	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
GCU45_RS00850	COG0791	NLP P60 protein
GCU45_RS00850	COG3883	PFAM NLP P60 protein
GCU45_RS00865	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS00875	COG0297	glycogen (starch) synthase activity
GCU45_RS00880	COG1116	anion transmembrane transporter activity
GCU45_RS00885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU45_RS00895	COG0371	Dehydrogenase
GCU45_RS00900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS00945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCU45_RS00950	COG5492	domain, Protein
GCU45_RS00955	COG3275	phosphorelay sensor kinase activity
GCU45_RS00960	COG4753	response regulator
GCU45_RS00960	COG2207	Transcriptional regulator
GCU45_RS00970	COG0395	ABC-type sugar transport system, permease component
GCU45_RS00975	COG4209	transmembrane transport
GCU45_RS00985	COG1082	Xylose isomerase domain protein TIM barrel
GCU45_RS00995	COG0673	inositol 2-dehydrogenase activity
GCU45_RS01015	COG0745	RESPONSE REGULATOR receiver
GCU45_RS01020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GCU45_RS01025	COG4988	ABC transporter
GCU45_RS01030	COG1294	oxidase, subunit
GCU45_RS01035	COG1271	oxidase subunit
GCU45_RS01040	COG1309	transcriptional regulator
GCU45_RS01060	COG2207	Transcriptional regulator
GCU45_RS01065	COG4221	oxidoreductase activity
GCU45_RS01075	COG2207	Transcriptional regulator
GCU45_RS01075	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS01100	COG0667	Aldo Keto reductase
GCU45_RS01105	COG0583	DNA-binding transcription factor activity
GCU45_RS01120	COG5002	protein histidine kinase activity
GCU45_RS01135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCU45_RS01155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCU45_RS01160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCU45_RS01185	COG0745	RESPONSE REGULATOR receiver
GCU45_RS01205	COG1335	isochorismatase
GCU45_RS01215	COG0789	Transcriptional regulator
GCU45_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS01235	COG0454	-acetyltransferase
GCU45_RS01235	COG0456	acetyltransferase
GCU45_RS01245	COG0667	Aldo Keto reductase
GCU45_RS01250	COG1846	Transcriptional regulator
GCU45_RS01255	COG2962	Rard protein
GCU45_RS01285	COG2267	carboxylic ester hydrolase activity
GCU45_RS01315	COG0583	DNA-binding transcription factor activity
GCU45_RS01320	COG0477	Major facilitator Superfamily
GCU45_RS01325	COG2207	Transcriptional regulator
GCU45_RS01330	COG4221	oxidoreductase activity
GCU45_RS01335	COG1309	transcriptional regulator
GCU45_RS01340	COG2814	Major facilitator Superfamily
GCU45_RS01355	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS01360	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS01370	COG3214	Protein conserved in bacteria
GCU45_RS01395	COG1619	proteins homologs of microcin C7 resistance protein MccF
GCU45_RS01400	COG1231	oxidoreductase activity
GCU45_RS01425	COG2816	NAD+ diphosphatase activity
GCU45_RS01430	COG0604	alcohol dehydrogenase
GCU45_RS01435	COG0640	Transcriptional regulator
GCU45_RS01445	COG3620	sequence-specific DNA binding
GCU45_RS01455	COG0768	penicillin binding
GCU45_RS01480	COG2267	carboxylic ester hydrolase activity
GCU45_RS01490	COG0673	inositol 2-dehydrogenase activity
GCU45_RS01495	COG4753	response regulator
GCU45_RS01495	COG2207	Transcriptional regulator
GCU45_RS01500	COG2972	Histidine kinase
GCU45_RS01505	COG0395	ABC-type sugar transport system, permease component
GCU45_RS01510	COG4209	transmembrane transport
GCU45_RS01515	COG1653	transport
GCU45_RS01520	COG0667	Aldo Keto reductase
GCU45_RS01525	COG1846	Transcriptional regulator
GCU45_RS01535	COG0596	Alpha beta hydrolase
GCU45_RS01545	COG0431	NADPH-dependent FMN reductase
GCU45_RS01565	COG1595	DNA-templated transcription, initiation
GCU45_RS01580	COG0277	FAD linked oxidase domain protein
GCU45_RS01595	COG2814	Major facilitator Superfamily
GCU45_RS01600	COG0583	DNA-binding transcription factor activity
GCU45_RS01610	COG1653	transport
GCU45_RS01615	COG0395	ABC-type sugar transport system, permease component
GCU45_RS01620	COG4209	transmembrane transport
GCU45_RS01625	COG2207	Transcriptional regulator
GCU45_RS01635	COG0655	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS01640	COG2814	Major facilitator Superfamily
GCU45_RS01660	COG5504	Zn-dependent protease
GCU45_RS01665	COG0789	Transcriptional regulator
GCU45_RS01670	COG2207	Transcriptional regulator
GCU45_RS01735	COG0656	L-ascorbic acid biosynthetic process
GCU45_RS01740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCU45_RS01750	COG1309	transcriptional regulator
GCU45_RS01755	COG0789	Transcriptional regulator
GCU45_RS01760	COG1064	alcohol dehydrogenase
GCU45_RS01765	COG0673	inositol 2-dehydrogenase activity
GCU45_RS01770	COG0673	inositol 2-dehydrogenase activity
GCU45_RS01780	COG0395	ABC-type sugar transport system, permease component
GCU45_RS01785	COG4209	transmembrane transport
GCU45_RS01805	COG2207	Transcriptional regulator
GCU45_RS01810	COG0395	ABC-type sugar transport system, permease component
GCU45_RS01815	COG4209	transmembrane transport
GCU45_RS01820	COG1653	transport
GCU45_RS01825	COG0697	spore germination
GCU45_RS01860	COG1733	regulation of RNA biosynthetic process
GCU45_RS01910	COG0697	spore germination
GCU45_RS01915	COG1309	transcriptional regulator
GCU45_RS01920	COG0024	Methionine aminopeptidase
GCU45_RS01925	COG4221	oxidoreductase activity
GCU45_RS01935	COG1595	DNA-templated transcription, initiation
GCU45_RS01950	COG1902	pentaerythritol trinitrate reductase activity
GCU45_RS02015	COG2378	regulation of single-species biofilm formation
GCU45_RS02040	COG2814	Major facilitator Superfamily
GCU45_RS02045	COG0025	NhaP-type Na H and K H
GCU45_RS02065	COG5566	PFAM Mor transcription activator
GCU45_RS02075	COG2814	Major facilitator Superfamily
GCU45_RS02090	COG0129	dihydroxy-acid dehydratase activity
GCU45_RS02115	COG2207	Transcriptional regulator
GCU45_RS02115	COG4753	response regulator
GCU45_RS02120	COG2972	Histidine kinase
GCU45_RS02130	COG0395	ABC-type sugar transport system, permease component
GCU45_RS02135	COG4209	transmembrane transport
GCU45_RS02185	COG0477	Major facilitator Superfamily
GCU45_RS02195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GCU45_RS02205	COG1733	regulation of RNA biosynthetic process
GCU45_RS02215	COG1733	regulation of RNA biosynthetic process
GCU45_RS02225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GCU45_RS02240	COG0583	DNA-binding transcription factor activity
GCU45_RS02245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GCU45_RS02255	COG2814	Major facilitator Superfamily
GCU45_RS02280	COG1486	melibiose metabolic process
GCU45_RS02285	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS02285	COG4977	sequence-specific DNA binding
GCU45_RS02295	COG3226	Transcriptional regulator
GCU45_RS02315	COG1959	2 iron, 2 sulfur cluster binding
GCU45_RS02330	COG0596	Alpha beta hydrolase
GCU45_RS02335	COG0667	Aldo Keto reductase
GCU45_RS02370	COG3848	Pyruvate phosphate dikinase
GCU45_RS02370	COG0574	Belongs to the PEP-utilizing enzyme family
GCU45_RS02405	COG0395	ABC-type sugar transport system, permease component
GCU45_RS02410	COG4209	transmembrane transport
GCU45_RS02420	COG0673	inositol 2-dehydrogenase activity
GCU45_RS02430	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS02430	COG2207	Transcriptional regulator
GCU45_RS02450	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS02450	COG2207	Transcriptional regulator
GCU45_RS02455	COG4948	Mandelate Racemase Muconate Lactonizing
GCU45_RS02460	COG0277	FAD linked oxidase domain protein
GCU45_RS02475	COG0477	Major facilitator Superfamily
GCU45_RS02480	COG0456	acetyltransferase
GCU45_RS02485	COG1846	Transcriptional regulator
GCU45_RS02490	COG1309	transcriptional regulator
GCU45_RS02495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GCU45_RS02505	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS02510	COG0583	DNA-binding transcription factor activity
GCU45_RS02520	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS02525	COG1309	transcriptional regulator
GCU45_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS02565	COG3878	Protein conserved in bacteria
GCU45_RS02570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCU45_RS02580	COG0667	Aldo Keto reductase
GCU45_RS02585	COG1809	phosphosulfolactate synthase activity
GCU45_RS02600	COG1335	isochorismatase
GCU45_RS02605	COG1733	regulation of RNA biosynthetic process
GCU45_RS02610	COG0778	Nitroreductase
GCU45_RS02625	COG4149	molybdate abc transporter
GCU45_RS02630	COG3842	ATPase activity
GCU45_RS02640	COG1175	transmembrane transport
GCU45_RS02660	COG1819	glycosyl
GCU45_RS02665	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GCU45_RS02670	COG2207	Transcriptional regulator
GCU45_RS02670	COG4753	response regulator
GCU45_RS02675	COG2972	Histidine kinase
GCU45_RS02685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GCU45_RS02690	COG0395	ABC-type sugar transport system, permease component
GCU45_RS02695	COG4209	transmembrane transport
GCU45_RS02700	COG0475	glutathione-regulated potassium exporter activity
GCU45_RS02710	COG1846	Transcriptional regulator
GCU45_RS02720	COG0702	epimerase
GCU45_RS02730	COG2315	Protein conserved in bacteria
GCU45_RS02800	COG2197	response regulator
GCU45_RS02805	COG0784	Response regulator, receiver
GCU45_RS02805	COG2205	protein histidine kinase activity
GCU45_RS02820	COG1595	DNA-templated transcription, initiation
GCU45_RS02835	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GCU45_RS02860	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS02870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GCU45_RS02875	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GCU45_RS02880	COG0709	Synthesizes selenophosphate from selenide and ATP
GCU45_RS02885	COG1876	peptidase activity
GCU45_RS02890	COG0431	NADPH-dependent FMN reductase
GCU45_RS02895	COG2346	COG2346, Truncated hemoglobins
GCU45_RS02900	COG0489	protein tyrosine kinase activity
GCU45_RS02935	COG0673	inositol 2-dehydrogenase activity
GCU45_RS02950	COG1846	Transcriptional regulator
GCU45_RS02955	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GCU45_RS02960	COG0813	purine-nucleoside phosphorylase activity
GCU45_RS02970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCU45_RS02975	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GCU45_RS02980	COG2390	Transcriptional regulator
GCU45_RS02985	COG1072	(Pantothenic acid kinase))
GCU45_RS02990	COG2409	Drug exporters of the RND superfamily
GCU45_RS03020	COG0242	peptide deformylase activity
GCU45_RS03025	COG0667	Aldo Keto reductase
GCU45_RS03035	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GCU45_RS03050	COG2309	aminopeptidase activity
GCU45_RS03055	COG2309	aminopeptidase activity
GCU45_RS03060	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS03085	COG2017	converts alpha-aldose to the beta-anomer
GCU45_RS03090	COG2205	protein histidine kinase activity
GCU45_RS03095	COG1595	DNA-templated transcription, initiation
GCU45_RS03110	COG4608	Belongs to the ABC transporter superfamily
GCU45_RS03115	COG0444	Belongs to the ABC transporter superfamily
GCU45_RS03125	COG0601	transmembrane transport
GCU45_RS03130	COG0747	negative chemotaxis
GCU45_RS03145	COG1253	flavin adenine dinucleotide binding
GCU45_RS03155	COG3773	Cell wall hydrolase
GCU45_RS03160	COG1175	transmembrane transport
GCU45_RS03165	COG0395	ABC-type sugar transport system, permease component
GCU45_RS03170	COG1653	transport
GCU45_RS03220	COG1309	transcriptional regulator
GCU45_RS03235	COG0583	DNA-binding transcription factor activity
GCU45_RS03255	COG1309	transcriptional regulator
GCU45_RS03270	COG0395	ABC-type sugar transport system, permease component
GCU45_RS03275	COG1175	transmembrane transport
GCU45_RS03300	COG1404	Belongs to the peptidase S8 family
GCU45_RS03310	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GCU45_RS03315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCU45_RS03320	COG2205	protein histidine kinase activity
GCU45_RS03335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GCU45_RS03340	COG0583	DNA-binding transcription factor activity
GCU45_RS03345	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS03345	COG2207	Transcriptional regulator
GCU45_RS03350	COG0697	spore germination
GCU45_RS03355	COG0395	ABC-type sugar transport system, permease component
GCU45_RS03360	COG1175	transmembrane transport
GCU45_RS03365	COG1653	transport
GCU45_RS03380	COG4209	transmembrane transport
GCU45_RS03385	COG1653	transport
GCU45_RS03395	COG2205	protein histidine kinase activity
GCU45_RS03400	COG1725	Transcriptional regulator
GCU45_RS03410	COG0842	Transport permease protein
GCU45_RS03410	COG1129	ABC transporter
GCU45_RS03420	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCU45_RS03425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GCU45_RS03430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GCU45_RS03435	COG2351	hydroxyisourate hydrolase activity
GCU45_RS03440	COG3648	Uricase
GCU45_RS03440	COG3195	allantoin biosynthetic process
GCU45_RS03445	COG3648	Uricase
GCU45_RS03445	COG3195	allantoin biosynthetic process
GCU45_RS03450	COG2080	2 iron, 2 sulfur cluster binding
GCU45_RS03455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GCU45_RS03465	COG2068	MobA-Related Protein
GCU45_RS03475	COG0402	S-adenosylhomocysteine deaminase activity
GCU45_RS03495	COG0154	amidase activity
GCU45_RS03510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU45_RS03520	COG0655	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS03525	COG0402	S-adenosylhomocysteine deaminase activity
GCU45_RS03535	COG0405	Gamma-glutamyltransferase
GCU45_RS03540	COG2059	Chromate
GCU45_RS03545	COG2059	Chromate
GCU45_RS03550	COG2508	Transcriptional regulator
GCU45_RS03570	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GCU45_RS03570	COG1082	Xylose isomerase domain protein TIM barrel
GCU45_RS03590	COG0395	ABC-type sugar transport system, permease component
GCU45_RS03595	COG4209	transmembrane transport
GCU45_RS03600	COG1609	Transcriptional regulator
GCU45_RS03610	COG1653	transport
GCU45_RS03615	COG0395	ABC-type sugar transport system, permease component
GCU45_RS03620	COG4209	transmembrane transport
GCU45_RS03625	COG2207	Transcriptional regulator
GCU45_RS03630	COG0667	Aldo Keto reductase
GCU45_RS03640	COG4974	Belongs to the 'phage' integrase family
GCU45_RS03645	COG1763	Mo-molybdopterin cofactor biosynthetic process
GCU45_RS03650	COG0303	'Molybdopterin
GCU45_RS03670	COG1842	Phage shock protein A
GCU45_RS03685	COG1388	LysM domain
GCU45_RS03685	COG3584	3D domain protein
GCU45_RS03690	COG1126	abc transporter atp-binding protein
GCU45_RS03695	COG0765	amino acid transport
GCU45_RS03700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU45_RS03710	COG0297	glycogen (starch) synthase activity
GCU45_RS03715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GCU45_RS03720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GCU45_RS03725	COG5002	protein histidine kinase activity
GCU45_RS03740	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GCU45_RS03745	COG0477	Major facilitator Superfamily
GCU45_RS03785	COG0493	'glutamate synthase
GCU45_RS03795	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GCU45_RS03800	COG0395	ABC-type sugar transport system, permease component
GCU45_RS03825	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCU45_RS03830	COG0022	dehydrogenase e1 component
GCU45_RS03840	COG2382	esterase
GCU45_RS03845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GCU45_RS03850	COG2860	membrane
GCU45_RS03860	COG0791	NLP P60 protein
GCU45_RS03865	COG0745	RESPONSE REGULATOR receiver
GCU45_RS03870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GCU45_RS03875	COG0488	(ABC) transporter
GCU45_RS03925	COG0515	serine threonine protein kinase
GCU45_RS03930	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GCU45_RS03935	COG1119	ATPase activity
GCU45_RS03940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCU45_RS03950	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GCU45_RS03960	COG0647	UMP catabolic process
GCU45_RS03965	COG1234	tRNA 3'-trailer cleavage
GCU45_RS03975	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GCU45_RS03985	COG1011	Hydrolase
GCU45_RS04005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GCU45_RS04010	COG2207	Transcriptional regulator
GCU45_RS04015	COG2972	Histidine kinase
GCU45_RS04020	COG0395	ABC-type sugar transport system, permease component
GCU45_RS04025	COG1175	transmembrane transport
GCU45_RS04030	COG1653	transport
GCU45_RS04050	COG0174	glutamine synthetase
GCU45_RS04055	COG0789	Transcriptional regulator
GCU45_RS04060	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GCU45_RS04065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GCU45_RS04070	COG0464	growth
GCU45_RS04085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCU45_RS04090	COG1923	regulation of RNA biosynthetic process
GCU45_RS04095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GCU45_RS04100	COG2521	methyltransferase
GCU45_RS04100	COG2136	Putative SAM-dependent methyltransferase
GCU45_RS04105	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GCU45_RS04110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GCU45_RS04125	COG4129	membrane
GCU45_RS04130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU45_RS04135	COG1116	anion transmembrane transporter activity
GCU45_RS04140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCU45_RS04145	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GCU45_RS04155	COG0288	reversible hydration of carbon dioxide
GCU45_RS04180	COG0351	phosphomethylpyrimidine kinase
GCU45_RS04200	COG1595	DNA-templated transcription, initiation
GCU45_RS04265	COG2207	Transcriptional regulator
GCU45_RS04295	COG3189	MarR family transcriptional regulator
GCU45_RS04315	COG3119	arylsulfatase activity
GCU45_RS04320	COG2207	Transcriptional regulator
GCU45_RS04325	COG2391	methyltransferase activity
GCU45_RS04330	COG0425	Belongs to the sulfur carrier protein TusA family
GCU45_RS04375	COG2971	BadF BadG BcrA BcrD
GCU45_RS04380	COG3876	Protein conserved in bacteria
GCU45_RS04395	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GCU45_RS04400	COG0395	ABC-type sugar transport system, permease component
GCU45_RS04405	COG1175	transmembrane transport
GCU45_RS04415	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GCU45_RS04425	COG0647	UMP catabolic process
GCU45_RS04430	COG1349	DNA-binding transcription factor activity
GCU45_RS04440	COG1063	alcohol dehydrogenase
GCU45_RS04450	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GCU45_RS04460	COG0366	Alpha amylase catalytic
GCU45_RS04480	COG1609	Transcriptional regulator
GCU45_RS04495	COG0667	Aldo Keto reductase
GCU45_RS04505	COG4608	Belongs to the ABC transporter superfamily
GCU45_RS04510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU45_RS04520	COG0747	negative chemotaxis
GCU45_RS04525	COG0444	Belongs to the ABC transporter superfamily
GCU45_RS04530	COG0154	amidase activity
GCU45_RS04540	COG0583	DNA-binding transcription factor activity
GCU45_RS04545	COG1335	isochorismatase
GCU45_RS04555	COG3250	beta-galactosidase activity
GCU45_RS04565	COG0395	ABC-type sugar transport system, permease component
GCU45_RS04595	COG0395	ABC-type sugar transport system, permease component
GCU45_RS04600	COG1175	transmembrane transport
GCU45_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS04610	COG2368	4-hydroxyphenylacetate
GCU45_RS04625	COG0116	Belongs to the methyltransferase superfamily
GCU45_RS04625	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GCU45_RS04645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GCU45_RS04650	COG0477	Major facilitator Superfamily
GCU45_RS04655	COG1846	Transcriptional regulator
GCU45_RS04660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GCU45_RS04670	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GCU45_RS04675	COG1131	(ABC) transporter
GCU45_RS04690	COG2340	Cysteine-rich secretory protein family
GCU45_RS04695	COG4211	Belongs to the binding-protein-dependent transport system permease family
GCU45_RS04705	COG1879	ABC-type sugar transport system periplasmic component
GCU45_RS04715	COG3275	phosphorelay sensor kinase activity
GCU45_RS04720	COG2207	Transcriptional regulator
GCU45_RS04730	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GCU45_RS04735	COG1132	(ABC) transporter
GCU45_RS04740	COG1132	(ABC) transporter
GCU45_RS04745	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GCU45_RS04755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GCU45_RS04770	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCU45_RS04780	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCU45_RS04785	COG0066	3-isopropylmalate dehydratase activity
GCU45_RS04790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GCU45_RS04795	COG0583	DNA-binding transcription factor activity
GCU45_RS04800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCU45_RS04805	COG0436	Aminotransferase
GCU45_RS04810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GCU45_RS04815	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GCU45_RS04820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GCU45_RS04825	COG1850	ribulose-bisphosphate carboxylase activity
GCU45_RS04830	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GCU45_RS04835	COG0235	Class ii aldolase
GCU45_RS04870	COG3935	DnaD domain protein
GCU45_RS04875	COG0017	Asparaginyl-tRNA synthetase
GCU45_RS04880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GCU45_RS04885	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCU45_RS04890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GCU45_RS04905	COG0402	S-adenosylhomocysteine deaminase activity
GCU45_RS04910	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GCU45_RS04915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCU45_RS04915	COG1199	ATP-dependent helicase activity
GCU45_RS04925	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GCU45_RS04930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GCU45_RS04935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GCU45_RS04940	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GCU45_RS04940	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GCU45_RS04945	COG0617	tRNA 3'-terminal CCA addition
GCU45_RS04950	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS04955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GCU45_RS04960	COG1803	Methylglyoxal synthase
GCU45_RS04965	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GCU45_RS04975	COG1694	Mazg nucleotide pyrophosphohydrolase
GCU45_RS04980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GCU45_RS04990	COG4347	Protein of unknown function (DUF1405)
GCU45_RS05020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GCU45_RS05030	COG0588	phosphoglycerate mutase activity
GCU45_RS05045	COG0287	Prephenate dehydrogenase
GCU45_RS05050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GCU45_RS05055	COG0159	tryptophan synthase activity
GCU45_RS05060	COG0133	tryptophan synthase activity
GCU45_RS05065	COG0135	phosphoribosylanthranilate isomerase activity
GCU45_RS05070	COG0134	indole-3-glycerol-phosphate synthase activity
GCU45_RS05075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GCU45_RS05085	COG4401	Chorismate mutase type I
GCU45_RS05090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GCU45_RS05095	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GCU45_RS05105	COG0105	UTP biosynthetic process
GCU45_RS05115	COG0163	prenyltransferase activity
GCU45_RS05120	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GCU45_RS05125	COG2226	methyltransferase
GCU45_RS05150	COG4211	Belongs to the binding-protein-dependent transport system permease family
GCU45_RS05155	COG1129	ABC transporter
GCU45_RS05165	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GCU45_RS05205	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GCU45_RS05210	COG1160	GTP binding
GCU45_RS05215	COG0539	negative regulation of cytoplasmic translation
GCU45_RS05220	COG0204	Acyl-transferase
GCU45_RS05225	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GCU45_RS05240	COG2959	enzyme of heme biosynthesis
GCU45_RS05245	COG2339	peptidase activity
GCU45_RS05250	COG4862	establishment of competence for transformation
GCU45_RS05265	COG1408	metallophosphoesterase
GCU45_RS05280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCU45_RS05285	COG5002	protein histidine kinase activity
GCU45_RS05290	COG0745	RESPONSE REGULATOR receiver
GCU45_RS05295	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCU45_RS05300	COG1333	cytochrome c biogenesis protein
GCU45_RS05305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCU45_RS05310	COG1187	pseudouridine synthase activity
GCU45_RS05320	COG0700	Nucleoside recognition
GCU45_RS05325	COG2715	membrane protein required for spore maturation
GCU45_RS05330	COG1686	Belongs to the peptidase S11 family
GCU45_RS05335	COG3874	Sporulation protein YtfJ
GCU45_RS05345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GCU45_RS05350	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GCU45_RS05360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GCU45_RS05360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GCU45_RS05370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCU45_RS05370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCU45_RS05375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCU45_RS05380	COG0019	diaminopimelate decarboxylase activity
GCU45_RS05385	COG0697	spore germination
GCU45_RS05405	COG2172	sigma factor antagonist activity
GCU45_RS05410	COG1366	Belongs to the anti-sigma-factor antagonist family
GCU45_RS05415	COG1686	Belongs to the peptidase S11 family
GCU45_RS05425	COG4974	Belongs to the 'phage' integrase family
GCU45_RS05435	COG0735	belongs to the Fur family
GCU45_RS05440	COG1300	Membrane
GCU45_RS05445	COG1379	DNA repair
GCU45_RS05465	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCU45_RS05475	COG0321	lipoyl(octanoyl) transferase activity
GCU45_RS05480	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCU45_RS05485	COG0022	dehydrogenase e1 component
GCU45_RS05490	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GCU45_RS05495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCU45_RS05515	COG1435	thymidine kinase activity
GCU45_RS05525	COG0658	competence protein
GCU45_RS05525	COG2333	competence protein COMEC
GCU45_RS05535	COG0745	RESPONSE REGULATOR receiver
GCU45_RS05540	COG0750	zinc metalloprotease
GCU45_RS05545	COG0497	DNA recombination
GCU45_RS05550	COG1438	arginine binding
GCU45_RS05560	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GCU45_RS05565	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GCU45_RS05575	COG1722	exodeoxyribonuclease VII activity
GCU45_RS05580	COG1570	exodeoxyribonuclease VII activity
GCU45_RS05585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GCU45_RS05590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GCU45_RS05605	COG1302	Protein conserved in bacteria
GCU45_RS05610	COG0439	Biotin carboxylase
GCU45_RS05615	COG0511	ligase activity, forming carbon-carbon bonds
GCU45_RS05655	COG3854	ATPases associated with a variety of cellular activities
GCU45_RS05675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GCU45_RS05680	COG0006	proline dipeptidase activity
GCU45_RS05685	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GCU45_RS05695	COG3872	metal-dependent enzyme
GCU45_RS05705	COG1752	Esterase of the alpha-beta hydrolase superfamily
GCU45_RS05710	COG1649	PFAM Uncharacterised BCR, COG1649
GCU45_RS05715	COG1321	iron dependent repressor
GCU45_RS05725	COG0785	Cytochrome C biogenesis protein
GCU45_RS05730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCU45_RS05735	COG1121	(ABC) transporter
GCU45_RS05740	COG0803	Belongs to the bacterial solute-binding protein 9 family
GCU45_RS05755	COG0735	belongs to the Fur family
GCU45_RS05760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCU45_RS05765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU45_RS05770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU45_RS05780	COG1472	Belongs to the glycosyl hydrolase 3 family
GCU45_RS05785	COG2207	Transcriptional regulator
GCU45_RS05785	COG4753	response regulator
GCU45_RS05790	COG2972	Histidine kinase
GCU45_RS05795	COG0395	ABC-type sugar transport system, permease component
GCU45_RS05800	COG1175	transmembrane transport
GCU45_RS05810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCU45_RS05820	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GCU45_RS05835	COG1733	regulation of RNA biosynthetic process
GCU45_RS05850	COG0673	inositol 2-dehydrogenase activity
GCU45_RS05860	COG0673	inositol 2-dehydrogenase activity
GCU45_RS05875	COG3754	Rhamnan synthesis protein F
GCU45_RS05885	COG0673	inositol 2-dehydrogenase activity
GCU45_RS05890	COG0861	Integral membrane protein TerC family
GCU45_RS05900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GCU45_RS05900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GCU45_RS05910	COG4876	unkown
GCU45_RS05915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GCU45_RS05950	COG1215	transferase activity, transferring glycosyl groups
GCU45_RS05970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GCU45_RS05975	COG2135	peptidase activity
GCU45_RS05985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCU45_RS06005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCU45_RS06010	COG1307	EDD domain protein, DegV family
GCU45_RS06015	COG1461	Dihydroxyacetone kinase
GCU45_RS06020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GCU45_RS06035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GCU45_RS06040	COG1162	GTPase activity
GCU45_RS06045	COG0515	serine threonine protein kinase
GCU45_RS06045	COG2815	serine threonine protein kinase
GCU45_RS06050	COG0631	protein serine/threonine phosphatase activity
GCU45_RS06055	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GCU45_RS06060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GCU45_RS06060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GCU45_RS06065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GCU45_RS06070	COG0242	peptide deformylase activity
GCU45_RS06075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GCU45_RS06080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GCU45_RS06085	COG1758	RNA polymerase activity
GCU45_RS06090	COG0194	GDP metabolic process
GCU45_RS06095	COG2052	Domain of unknown function (DUF370)
GCU45_RS06100	COG1561	YicC-like family, N-terminal region
GCU45_RS06105	COG0646	methionine synthase
GCU45_RS06105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GCU45_RS06110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GCU45_RS06115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GCU45_RS06120	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GCU45_RS06125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GCU45_RS06135	COG0583	DNA-binding transcription factor activity
GCU45_RS06145	COG4471	UPF0298 protein
GCU45_RS06165	COG1473	amidohydrolase
GCU45_RS06175	COG0772	Belongs to the SEDS family
GCU45_RS06180	COG1302	Protein conserved in bacteria
GCU45_RS06185	COG0387	Pfam Sodium calcium exchanger
GCU45_RS06190	COG4838	Belongs to the UPF0358 family
GCU45_RS06210	COG2203	Gaf domain
GCU45_RS06210	COG2199	diguanylate cyclase activity
GCU45_RS06215	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GCU45_RS06220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GCU45_RS06225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCU45_RS06230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GCU45_RS06235	COG0454	-acetyltransferase
GCU45_RS06240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCU45_RS06245	COG1609	Transcriptional regulator
GCU45_RS06260	COG0693	protein deglycase activity
GCU45_RS06265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCU45_RS06270	COG2190	(PTS) system
GCU45_RS06270	COG1263	PTS System
GCU45_RS06270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCU45_RS06275	COG1832	CoA-binding protein
GCU45_RS06280	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GCU45_RS06285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCU45_RS06290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GCU45_RS06300	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GCU45_RS06310	COG4493	Belongs to the UPF0637 family
GCU45_RS06315	COG2814	Major facilitator Superfamily
GCU45_RS06320	COG1982	Orn Lys Arg decarboxylase major
GCU45_RS06325	COG3906	Belongs to the UPF0473 family
GCU45_RS06340	COG1234	tRNA 3'-trailer cleavage
GCU45_RS06350	COG2153	protein acetylation
GCU45_RS06380	COG0584	glycerophosphoryl diester phosphodiesterase
GCU45_RS06400	COG0628	permease
GCU45_RS06410	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GCU45_RS06435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GCU45_RS06450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GCU45_RS06460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GCU45_RS06465	COG0540	Belongs to the ATCase OTCase family
GCU45_RS06470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GCU45_RS06475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCU45_RS06480	COG0805	protein transport
GCU45_RS06495	COG0436	Aminotransferase
GCU45_RS06500	COG0564	pseudouridine synthase activity
GCU45_RS06525	COG3599	regulation of cell shape
GCU45_RS06530	COG2302	S4 RNA-binding domain
GCU45_RS06535	COG0762	integral membrane protein
GCU45_RS06540	COG1799	cell septum assembly
GCU45_RS06545	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GCU45_RS06550	COG1496	oxidoreductase activity
GCU45_RS06555	COG1873	PFAM PRC-barrel domain
GCU45_RS06560	COG1191	sigma factor activity
GCU45_RS06565	COG1191	sigma factor activity
GCU45_RS06575	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GCU45_RS06580	COG0849	cell division
GCU45_RS06585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GCU45_RS06590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GCU45_RS06595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GCU45_RS06600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GCU45_RS06605	COG0772	Belongs to the SEDS family
GCU45_RS06610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GCU45_RS06615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCU45_RS06620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GCU45_RS06630	COG0768	penicillin binding
GCU45_RS06635	COG0768	penicillin binding
GCU45_RS06645	COG0275	rRNA processing
GCU45_RS06650	COG2001	Belongs to the MraZ family
GCU45_RS06655	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GCU45_RS06660	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GCU45_RS06665	COG4608	Belongs to the ABC transporter superfamily
GCU45_RS06670	COG0444	Belongs to the ABC transporter superfamily
GCU45_RS06675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU45_RS06680	COG0601	transmembrane transport
GCU45_RS06685	COG4166	transmembrane transport
GCU45_RS06695	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GCU45_RS06720	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GCU45_RS06730	COG1316	TRANSCRIPTIONal
GCU45_RS06740	COG1217	gtp-binding protein TYPA
GCU45_RS06750	COG0861	Integral membrane protein TerC family
GCU45_RS06755	COG0861	Integral membrane protein TerC family
GCU45_RS06760	COG0301	tRNA thio-modification
GCU45_RS06765	COG1104	cysteine desulfurase activity
GCU45_RS06770	COG0741	lytic transglycosylase activity
GCU45_RS06805	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GCU45_RS06810	COG2384	SAM-dependent methyltransferase
GCU45_RS06820	COG0358	DNA primase activity
GCU45_RS06825	COG1671	Belongs to the UPF0178 family
GCU45_RS06830	COG0751	glycine-tRNA ligase activity
GCU45_RS06835	COG0752	glycyl-tRNA synthetase alpha subunit
GCU45_RS06840	COG1381	Involved in DNA repair and RecF pathway recombination
GCU45_RS06850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GCU45_RS06860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GCU45_RS06865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GCU45_RS06870	COG1480	7TM receptor with intracellular HD hydrolase
GCU45_RS06875	COG1702	phosphate starvation-inducible protein PhoH
GCU45_RS06895	COG4864	UPF0365 protein
GCU45_RS06900	COG1030	water channel activity
GCU45_RS06905	COG1610	YqeY-like protein
GCU45_RS06910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GCU45_RS06915	COG0537	adenosine 5'-monophosphoramidase activity
GCU45_RS06925	COG0419	ATPase involved in DNA repair
GCU45_RS06930	COG0420	3'-5' exonuclease activity
GCU45_RS06935	COG1074	ATP-dependent DNA helicase activity
GCU45_RS06940	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GCU45_RS06945	COG0640	Transcriptional regulator
GCU45_RS06960	COG1694	Mazg nucleotide pyrophosphohydrolase
GCU45_RS06975	COG1283	sodium-dependent phosphate transmembrane transporter activity
GCU45_RS06985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GCU45_RS06990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GCU45_RS06995	COG1994	Peptidase M50
GCU45_RS07000	COG2264	protein methyltransferase activity
GCU45_RS07030	COG0459	protein refolding
GCU45_RS07035	COG1420	regulation of RNA biosynthetic process
GCU45_RS07040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GCU45_RS07040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GCU45_RS07045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCU45_RS07050	COG0481	GTPase activity
GCU45_RS07070	COG0268	Binds directly to 16S ribosomal RNA
GCU45_RS07075	COG2814	Major facilitator Superfamily
GCU45_RS07080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GCU45_RS07090	COG2132	Multicopper oxidase
GCU45_RS07095	COG1466	dna polymerase III delta subunit
GCU45_RS07105	COG1595	DNA-templated transcription, initiation
GCU45_RS07110	COG2333	competence protein COMEC
GCU45_RS07110	COG0658	competence protein
GCU45_RS07120	COG1555	photosystem II stabilization
GCU45_RS07125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GCU45_RS07130	COG0495	leucyl-tRNA aminoacylation
GCU45_RS07135	COG4977	sequence-specific DNA binding
GCU45_RS07135	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS07140	COG3708	Transcriptional regulator
GCU45_RS07140	COG2207	Transcriptional regulator
GCU45_RS07160	COG3639	organic phosphonate transmembrane transporter activity
GCU45_RS07165	COG3639	organic phosphonate transmembrane transporter activity
GCU45_RS07170	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GCU45_RS07180	COG4778	phosphonate C-P lyase system protein PhnL
GCU45_RS07185	COG3454	Phosphonate metabolism
GCU45_RS07190	COG4107	phosphonate C-P lyase system protein PhnK
GCU45_RS07195	COG3627	carbon phosphorus lyase activity
GCU45_RS07225	COG0613	PHP domain protein
GCU45_RS07230	COG0300	oxidoreductase activity
GCU45_RS07235	COG2226	methyltransferase
GCU45_RS07240	COG2996	Protein conserved in bacteria
GCU45_RS07245	COG0799	negative regulation of ribosome biogenesis
GCU45_RS07250	COG1713	HD superfamily hydrolase involved in NAD metabolism
GCU45_RS07255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GCU45_RS07260	COG1534	Rna-binding protein
GCU45_RS07265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GCU45_RS07270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GCU45_RS07275	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GCU45_RS07280	COG1305	Transglutaminase-like
GCU45_RS07290	COG0714	Associated with various cellular activities
GCU45_RS07300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GCU45_RS07310	COG1363	Peptidase, m42
GCU45_RS07315	COG0431	NADPH-dependent FMN reductase
GCU45_RS07325	COG1929	Belongs to the glycerate kinase type-1 family
GCU45_RS07330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCU45_RS07335	COG3420	alginic acid biosynthetic process
GCU45_RS07340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCU45_RS07345	COG1486	melibiose metabolic process
GCU45_RS07350	COG0395	ABC-type sugar transport system, permease component
GCU45_RS07355	COG1175	transmembrane transport
GCU45_RS07365	COG1609	Transcriptional regulator
GCU45_RS07385	COG2217	Heavy metal translocating P-type atpase
GCU45_RS07390	COG2608	mercury ion transmembrane transporter activity
GCU45_RS07400	COG2706	6-phosphogluconolactonase activity
GCU45_RS07425	COG0395	ABC-type sugar transport system, permease component
GCU45_RS07430	COG1175	transmembrane transport
GCU45_RS07440	COG1609	Transcriptional regulator
GCU45_RS07445	COG4565	transcriptional regulatory protein
GCU45_RS07450	COG3275	phosphorelay sensor kinase activity
GCU45_RS07470	COG1175	transmembrane transport
GCU45_RS07475	COG0395	ABC-type sugar transport system, permease component
GCU45_RS07485	COG1054	Belongs to the UPF0176 family
GCU45_RS07505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GCU45_RS07510	COG0488	(ABC) transporter
GCU45_RS07515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GCU45_RS07525	COG1523	belongs to the glycosyl hydrolase 13 family
GCU45_RS07530	COG0509	glycine decarboxylation via glycine cleavage system
GCU45_RS07535	COG1760	l-serine dehydratase
GCU45_RS07540	COG1760	l-serine dehydratase
GCU45_RS07545	COG1940	carbohydrate kinase activity
GCU45_RS07555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GCU45_RS07560	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GCU45_RS07565	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GCU45_RS07570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCU45_RS07575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCU45_RS07580	COG3711	transcriptional antiterminator
GCU45_RS07585	COG0583	DNA-binding transcription factor activity
GCU45_RS07590	COG2272	Belongs to the type-B carboxylesterase lipase family
GCU45_RS07595	COG0730	response to heat
GCU45_RS07600	COG2268	Band 7 protein
GCU45_RS07610	COG0789	Transcriptional regulator
GCU45_RS07630	COG2814	Major facilitator Superfamily
GCU45_RS07635	COG1979	alcohol dehydrogenase
GCU45_RS07640	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GCU45_RS07645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GCU45_RS07650	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GCU45_RS07660	COG0667	Aldo Keto reductase
GCU45_RS07665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GCU45_RS07670	COG0800	Aldolase
GCU45_RS07685	COG0129	dihydroxy-acid dehydratase activity
GCU45_RS07695	COG0628	permease
GCU45_RS07700	COG0768	penicillin binding
GCU45_RS07705	COG0840	transmembrane signaling receptor activity
GCU45_RS07710	COG0738	Major facilitator superfamily
GCU45_RS07715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GCU45_RS07720	COG1063	alcohol dehydrogenase
GCU45_RS07725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCU45_RS07735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GCU45_RS07740	COG3906	Belongs to the UPF0473 family
GCU45_RS07750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GCU45_RS07760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GCU45_RS07765	COG0628	permease
GCU45_RS07780	COG1104	cysteine desulfurase activity
GCU45_RS07790	COG1959	2 iron, 2 sulfur cluster binding
GCU45_RS07795	COG0482	sulfurtransferase activity
GCU45_RS07800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GCU45_RS07855	COG2508	Transcriptional regulator
GCU45_RS07870	COG1309	transcriptional regulator
GCU45_RS07880	COG3973	AAA domain
GCU45_RS07895	COG3481	metal-dependent phosphohydrolase, HD sub domain
GCU45_RS07905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GCU45_RS07910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GCU45_RS07915	COG0124	histidyl-tRNA synthetase
GCU45_RS07925	COG0693	protein deglycase activity
GCU45_RS07930	COG1490	D-aminoacyl-tRNA deacylase activity
GCU45_RS07935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCU45_RS07940	COG2233	PERMEase
GCU45_RS07960	COG0395	ABC-type sugar transport system, permease component
GCU45_RS07975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GCU45_RS07980	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GCU45_RS07980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GCU45_RS07985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GCU45_RS07990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCU45_RS07995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCU45_RS07995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCU45_RS08005	COG2244	polysaccharide biosynthetic process
GCU45_RS08010	COG2323	membrane
GCU45_RS08025	COG1862	Preprotein translocase
GCU45_RS08035	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GCU45_RS08040	COG2385	sporulation resulting in formation of a cellular spore
GCU45_RS08040	COG2385	sporulation resulting in formation of a cellular spore
GCU45_RS08045	COG2255	four-way junction helicase activity
GCU45_RS08050	COG0632	four-way junction helicase activity
GCU45_RS08055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GCU45_RS08060	COG0583	DNA-binding transcription factor activity
GCU45_RS08065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCU45_RS08145	COG1388	LysM domain
GCU45_RS08150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCU45_RS08155	COG0077	Prephenate dehydratase
GCU45_RS08160	COG0083	homoserine kinase activity
GCU45_RS08165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GCU45_RS08170	COG0460	homoserine dehydrogenase
GCU45_RS08175	COG4492	Belongs to the UPF0735 family
GCU45_RS08180	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GCU45_RS08195	COG2868	ribosomal protein
GCU45_RS08200	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GCU45_RS08210	COG1994	Peptidase M50
GCU45_RS08220	COG1174	glycine betaine transport
GCU45_RS08225	COG1732	Glycine betaine
GCU45_RS08235	COG1125	glycine betaine transport
GCU45_RS08235	COG0517	IMP dehydrogenase activity
GCU45_RS08240	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GCU45_RS08245	COG2894	cell division
GCU45_RS08250	COG0850	regulation of cytokinetic process
GCU45_RS08265	COG1077	Cell shape determining protein MreB Mrl
GCU45_RS08270	COG2003	Belongs to the UPF0758 family
GCU45_RS08275	COG0424	maF-like protein
GCU45_RS08290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GCU45_RS08295	COG0285	dihydrofolate synthase activity
GCU45_RS08300	COG0525	valine-tRNA ligase activity
GCU45_RS08305	COG1388	LysM domain
GCU45_RS08310	COG0564	pseudouridine synthase activity
GCU45_RS08315	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GCU45_RS08320	COG0113	porphobilinogen synthase activity
GCU45_RS08335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GCU45_RS08335	COG1648	precorrin-2 dehydrogenase activity
GCU45_RS08340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCU45_RS08355	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GCU45_RS08365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GCU45_RS08375	COG0470	DNA polymerase III
GCU45_RS08375	COG1067	ATP-dependent peptidase activity
GCU45_RS08385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GCU45_RS08390	COG0740	serine-type endopeptidase activity
GCU45_RS08395	COG0544	peptidyl-prolyl cis-trans isomerase activity
GCU45_RS08425	COG0395	ABC-type sugar transport system, permease component
GCU45_RS08430	COG1175	transmembrane transport
GCU45_RS08440	COG4753	response regulator
GCU45_RS08440	COG2207	Transcriptional regulator
GCU45_RS08445	COG2972	Histidine kinase
GCU45_RS08450	COG1132	(ABC) transporter
GCU45_RS08455	COG1132	(ABC) transporter
GCU45_RS08460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCU45_RS08470	COG2807	transmembrane transport
GCU45_RS08475	COG2186	Transcriptional regulator
GCU45_RS08485	COG1940	carbohydrate kinase activity
GCU45_RS08495	COG1175	transmembrane transport
GCU45_RS08500	COG0395	ABC-type sugar transport system, permease component
GCU45_RS08520	COG0581	inorganic phosphate transmembrane transporter activity
GCU45_RS08525	COG0573	inorganic phosphate transmembrane transporter activity
GCU45_RS08530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GCU45_RS08535	COG1489	DNA binding
GCU45_RS08540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCU45_RS08570	COG0367	asparagine synthase
GCU45_RS08575	COG1609	Transcriptional regulator
GCU45_RS08580	COG3459	Glycosyltransferase 36 associated
GCU45_RS08595	COG0395	ABC-type sugar transport system, permease component
GCU45_RS08600	COG4209	transmembrane transport
GCU45_RS08615	COG4154	Belongs to the RbsD FucU family
GCU45_RS08620	COG2211	Major facilitator Superfamily
GCU45_RS08630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GCU45_RS08635	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GCU45_RS08640	COG5401	PFAM Sporulation and spore germination
GCU45_RS08645	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GCU45_RS08660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU45_RS08670	COG1227	inorganic diphosphatase activity
GCU45_RS08710	COG2197	response regulator
GCU45_RS08715	COG2822	iron ion transport
GCU45_RS08720	COG2837	iron assimilation
GCU45_RS08725	COG0672	)-iron permease
GCU45_RS08730	COG1737	Transcriptional regulator
GCU45_RS08735	COG0363	glucosamine-6-phosphate deaminase activity
GCU45_RS08765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCU45_RS08775	COG0673	inositol 2-dehydrogenase activity
GCU45_RS08790	COG1216	Glycosyl transferase, family 2
GCU45_RS08795	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS08820	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS08825	COG1216	Glycosyl transferase, family 2
GCU45_RS08830	COG1088	dTDP-glucose 4,6-dehydratase activity
GCU45_RS08835	COG1091	dTDP-4-dehydrorhamnose reductase activity
GCU45_RS08850	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS08855	COG4641	Protein conserved in bacteria
GCU45_RS08895	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GCU45_RS08925	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GCU45_RS08930	COG1122	ATPase activity
GCU45_RS08940	COG0688	phosphatidylethanolamine metabolic process
GCU45_RS08945	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS08980	COG1131	(ABC) transporter
GCU45_RS08990	COG0300	oxidoreductase activity
GCU45_RS09000	COG0583	DNA-binding transcription factor activity
GCU45_RS09005	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GCU45_RS09010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU45_RS09025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GCU45_RS09030	COG1053	succinate dehydrogenase
GCU45_RS09035	COG2009	succinate dehydrogenase
GCU45_RS09040	COG0583	DNA-binding transcription factor activity
GCU45_RS09050	COG0569	domain protein
GCU45_RS09055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GCU45_RS09065	COG0322	excinuclease ABC activity
GCU45_RS09070	COG3118	belongs to the thioredoxin family
GCU45_RS09080	COG1484	DNA-dependent DNA replication
GCU45_RS09090	COG1073	alpha beta
GCU45_RS09100	COG3253	May function as heme-dependent peroxidase
GCU45_RS09110	COG1252	NADH dehydrogenase
GCU45_RS09120	COG0492	ferredoxin-NADP+ reductase activity
GCU45_RS09130	COG0189	ligase activity
GCU45_RS09140	COG0316	Belongs to the HesB IscA family
GCU45_RS09145	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GCU45_RS09150	COG1252	NADH dehydrogenase
GCU45_RS09155	COG4844	belongs to the
GCU45_RS09160	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GCU45_RS09170	COG5002	protein histidine kinase activity
GCU45_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS09205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GCU45_RS09210	COG1612	heme a metabolic process
GCU45_RS09215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCU45_RS09225	COG2244	polysaccharide biosynthetic process
GCU45_RS09235	COG0561	phosphatase activity
GCU45_RS09240	COG0768	penicillin binding
GCU45_RS09245	COG0768	penicillin binding
GCU45_RS09270	COG2223	nitrite transmembrane transporter activity
GCU45_RS09275	COG2217	Heavy metal translocating P-type atpase
GCU45_RS09280	COG1522	sequence-specific DNA binding
GCU45_RS09285	COG0730	response to heat
GCU45_RS09295	COG3263	regulation of cellular component size
GCU45_RS09300	COG0129	dihydroxy-acid dehydratase activity
GCU45_RS09305	COG1802	Transcriptional regulator
GCU45_RS09310	COG1733	regulation of RNA biosynthetic process
GCU45_RS09335	COG2205	protein histidine kinase activity
GCU45_RS09350	COG2205	protein histidine kinase activity
GCU45_RS09365	COG0583	DNA-binding transcription factor activity
GCU45_RS09370	COG2116	formate transmembrane transporter activity
GCU45_RS09380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GCU45_RS09385	COG5609	conserved protein (DUF2294)
GCU45_RS09390	COG3383	formate dehydrogenase (NAD+) activity
GCU45_RS09395	COG2427	Protein of unknown function (DUF1641)
GCU45_RS09405	COG0386	Belongs to the glutathione peroxidase family
GCU45_RS09445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GCU45_RS09460	COG4948	Mandelate Racemase Muconate Lactonizing
GCU45_RS09465	COG1312	Catalyzes the dehydration of D-mannonate
GCU45_RS09475	COG0395	ABC-type sugar transport system, permease component
GCU45_RS09480	COG1175	transmembrane transport
GCU45_RS09490	COG2207	Transcriptional regulator
GCU45_RS09500	COG0840	transmembrane signaling receptor activity
GCU45_RS09510	COG1472	Belongs to the glycosyl hydrolase 3 family
GCU45_RS09515	COG0247	lactate metabolic process
GCU45_RS09520	COG0277	FAD linked oxidase domain protein
GCU45_RS09525	COG2186	Transcriptional regulator
GCU45_RS09530	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GCU45_RS09540	COG1959	2 iron, 2 sulfur cluster binding
GCU45_RS09545	COG2910	NAD(P)H-binding
GCU45_RS09570	COG0667	Aldo Keto reductase
GCU45_RS09575	COG0477	Major facilitator Superfamily
GCU45_RS09580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GCU45_RS09585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GCU45_RS09590	COG0640	Transcriptional regulator
GCU45_RS09605	COG2226	methyltransferase
GCU45_RS09625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCU45_RS09630	COG1845	cytochrome c oxidase, subunit III
GCU45_RS09635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GCU45_RS09650	COG3279	Response regulator of the LytR AlgR family
GCU45_RS09660	COG1737	Transcriptional regulator
GCU45_RS09670	COG1253	flavin adenine dinucleotide binding
GCU45_RS09675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCU45_RS09690	COG1070	Carbohydrate kinase
GCU45_RS09710	COG4608	Belongs to the ABC transporter superfamily
GCU45_RS09715	COG0444	Belongs to the ABC transporter superfamily
GCU45_RS09725	COG0601	transmembrane transport
GCU45_RS09740	COG3266	domain, Protein
GCU45_RS09740	COG1361	Conserved repeat domain
GCU45_RS09740	COG2911	Protein conserved in bacteria
GCU45_RS09755	COG0737	Belongs to the 5'-nucleotidase family
GCU45_RS09765	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GCU45_RS09770	COG3639	organic phosphonate transmembrane transporter activity
GCU45_RS09795	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GCU45_RS09830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GCU45_RS09840	COG0084	hydrolase, TatD family'
GCU45_RS09865	COG0454	-acetyltransferase
GCU45_RS09870	COG0778	Nitroreductase
GCU45_RS09880	COG0784	Response regulator, receiver
GCU45_RS09880	COG2205	protein histidine kinase activity
GCU45_RS09880	COG2198	Histidine kinase
GCU45_RS09895	COG0673	inositol 2-dehydrogenase activity
GCU45_RS09900	COG4474	Belongs to the UPF0398 family
GCU45_RS09905	COG1566	PFAM secretion protein HlyD family protein
GCU45_RS09910	COG0477	Major facilitator Superfamily
GCU45_RS09915	COG1846	Transcriptional regulator
GCU45_RS09920	COG3940	Belongs to the glycosyl hydrolase 43 family
GCU45_RS09935	COG0395	ABC-type sugar transport system, permease component
GCU45_RS09940	COG1175	transmembrane transport
GCU45_RS09960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCU45_RS09965	COG1069	ribulokinase activity
GCU45_RS09980	COG2160	L-arabinose isomerase activity
GCU45_RS09985	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCU45_RS09995	COG2514	catechol 2,3-dioxygenase activity
GCU45_RS10010	COG3119	arylsulfatase activity
GCU45_RS10015	COG1940	carbohydrate kinase activity
GCU45_RS10020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GCU45_RS10025	COG1733	regulation of RNA biosynthetic process
GCU45_RS10035	COG2746	aminoglycoside 3-N-acetyltransferase activity
GCU45_RS10055	COG0383	alpha-mannosidase activity
GCU45_RS10090	COG0395	ABC-type sugar transport system, permease component
GCU45_RS10095	COG4209	transmembrane transport
GCU45_RS10100	COG3152	Membrane
GCU45_RS10115	COG1733	regulation of RNA biosynthetic process
GCU45_RS10120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GCU45_RS10135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GCU45_RS10160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCU45_RS10180	COG0395	ABC-type sugar transport system, permease component
GCU45_RS10185	COG4209	transmembrane transport
GCU45_RS10205	COG0406	alpha-ribazole phosphatase activity
GCU45_RS10215	COG3403	YqcI/YcgG family
GCU45_RS10220	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS10235	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GCU45_RS10240	COG2207	Transcriptional regulator
GCU45_RS10240	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS10250	COG3341	Caulimovirus viroplasmin
GCU45_RS10250	COG0328	RNA-DNA hybrid ribonuclease activity
GCU45_RS10255	COG0824	Thioesterase
GCU45_RS10260	COG1119	ATPase activity
GCU45_RS10270	COG0477	Major facilitator Superfamily
GCU45_RS10380	COG0861	Integral membrane protein TerC family
GCU45_RS10395	COG3181	Tripartite tricarboxylate transporter family receptor
GCU45_RS10400	COG3290	protein histidine kinase activity
GCU45_RS10405	COG4565	transcriptional regulatory protein
GCU45_RS10425	COG0673	inositol 2-dehydrogenase activity
GCU45_RS10440	COG0653	protein targeting
GCU45_RS10445	COG0326	Molecular chaperone. Has ATPase activity
GCU45_RS10450	COG0395	ABC-type sugar transport system, permease component
GCU45_RS10455	COG4209	transmembrane transport
GCU45_RS10470	COG3275	phosphorelay sensor kinase activity
GCU45_RS10480	COG0673	inositol 2-dehydrogenase activity
GCU45_RS10485	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GCU45_RS10490	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GCU45_RS10495	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS10500	COG3250	beta-galactosidase activity
GCU45_RS10505	COG0395	ABC-type sugar transport system, permease component
GCU45_RS10510	COG1175	transmembrane transport
GCU45_RS10520	COG4753	response regulator
GCU45_RS10520	COG2207	Transcriptional regulator
GCU45_RS10525	COG5000	phosphorelay sensor kinase activity
GCU45_RS10530	COG3408	Glycogen debranching enzyme
GCU45_RS10530	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GCU45_RS10565	COG0395	ABC-type sugar transport system, permease component
GCU45_RS10575	COG3842	ATPase activity
GCU45_RS10580	COG2182	Extracellular solute-binding protein
GCU45_RS10590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCU45_RS10600	COG1940	carbohydrate kinase activity
GCU45_RS10605	COG0523	cobalamin synthesis protein
GCU45_RS10610	COG0701	Predicted permease
GCU45_RS10620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCU45_RS10625	COG0667	Aldo Keto reductase
GCU45_RS10630	COG1733	regulation of RNA biosynthetic process
GCU45_RS10645	COG1309	transcriptional regulator
GCU45_RS10650	COG2124	cytochrome p450
GCU45_RS10660	COG0457	Tetratricopeptide repeat
GCU45_RS10685	COG2972	Histidine kinase
GCU45_RS10690	COG2169	Transcriptional regulator
GCU45_RS10695	COG4209	transmembrane transport
GCU45_RS10700	COG0395	ABC-type sugar transport system, permease component
GCU45_RS10725	COG5434	Belongs to the glycosyl hydrolase 28 family
GCU45_RS10730	COG1653	transport
GCU45_RS10735	COG0395	ABC-type sugar transport system, permease component
GCU45_RS10740	COG4209	transmembrane transport
GCU45_RS10745	COG2207	Transcriptional regulator
GCU45_RS10760	COG0656	L-ascorbic acid biosynthetic process
GCU45_RS10790	COG1609	Transcriptional regulator
GCU45_RS10800	COG0439	Biotin carboxylase
GCU45_RS10805	COG3665	Urea carboxylase-associated protein
GCU45_RS10815	COG0531	amino acid
GCU45_RS10835	COG3266	domain, Protein
GCU45_RS10835	COG1361	Conserved repeat domain
GCU45_RS10835	COG2911	Protein conserved in bacteria
GCU45_RS10840	COG2909	trisaccharide binding
GCU45_RS10850	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS10865	COG3275	phosphorelay sensor kinase activity
GCU45_RS10870	COG2207	Transcriptional regulator
GCU45_RS10870	COG4753	response regulator
GCU45_RS10875	COG1653	transport
GCU45_RS10880	COG0395	ABC-type sugar transport system, permease component
GCU45_RS10885	COG4209	transmembrane transport
GCU45_RS10915	COG3655	Transcriptional regulator
GCU45_RS10920	COG3739	integral membrane protein
GCU45_RS10930	COG3279	Response regulator of the LytR AlgR family
GCU45_RS10935	COG2972	Histidine kinase
GCU45_RS10935	COG0745	RESPONSE REGULATOR receiver
GCU45_RS10940	COG2954	triphosphatase activity
GCU45_RS10960	COG0346	lactoylglutathione lyase activity
GCU45_RS10985	COG1940	carbohydrate kinase activity
GCU45_RS10990	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GCU45_RS10995	COG3395	kinase activity
GCU45_RS11000	COG0235	Class ii aldolase
GCU45_RS11005	COG0383	alpha-mannosidase activity
GCU45_RS11045	COG1175	transmembrane transport
GCU45_RS11050	COG1609	Transcriptional regulator
GCU45_RS11055	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GCU45_RS11060	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS11065	COG0789	Transcriptional regulator
GCU45_RS11090	COG2814	Major facilitator Superfamily
GCU45_RS11100	COG2972	Histidine kinase
GCU45_RS11105	COG4753	response regulator
GCU45_RS11105	COG2207	Transcriptional regulator
GCU45_RS11110	COG1653	transport
GCU45_RS11115	COG1175	transmembrane transport
GCU45_RS11120	COG0395	ABC-type sugar transport system, permease component
GCU45_RS11125	COG1959	2 iron, 2 sulfur cluster binding
GCU45_RS11130	COG0596	Alpha beta hydrolase
GCU45_RS11155	COG0513	Belongs to the DEAD box helicase family
GCU45_RS11170	COG1175	transmembrane transport
GCU45_RS11175	COG0395	ABC-type sugar transport system, permease component
GCU45_RS11190	COG0596	Alpha beta hydrolase
GCU45_RS11195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GCU45_RS11200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GCU45_RS11205	COG2814	Major facilitator Superfamily
GCU45_RS11215	COG3764	Sortase (surface protein transpeptidase)
GCU45_RS11225	COG3279	Response regulator of the LytR AlgR family
GCU45_RS11230	COG0745	RESPONSE REGULATOR receiver
GCU45_RS11230	COG2972	Histidine kinase
GCU45_RS11235	COG3940	Belongs to the glycosyl hydrolase 43 family
GCU45_RS11240	COG3940	Belongs to the glycosyl hydrolase 43 family
GCU45_RS11245	COG3250	beta-galactosidase activity
GCU45_RS11255	COG3940	Belongs to the glycosyl hydrolase 43 family
GCU45_RS11260	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS11260	COG2169	Transcriptional regulator
GCU45_RS11270	COG2244	polysaccharide biosynthetic process
GCU45_RS11290	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS11295	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GCU45_RS11295	COG0662	Cupin 2, conserved barrel domain protein
GCU45_RS11305	COG4585	Histidine kinase
GCU45_RS11310	COG2197	response regulator
GCU45_RS11340	COG0640	Transcriptional regulator
GCU45_RS11345	COG0657	acetylesterase activity
GCU45_RS11350	COG1733	regulation of RNA biosynthetic process
GCU45_RS11375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GCU45_RS11380	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCU45_RS11390	COG2807	transmembrane transport
GCU45_RS11395	COG0583	DNA-binding transcription factor activity
GCU45_RS11400	COG3206	protein involved in exopolysaccharide biosynthesis
GCU45_RS11440	COG4585	Histidine kinase
GCU45_RS11445	COG2197	response regulator
GCU45_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS11465	COG1846	Transcriptional regulator
GCU45_RS11470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GCU45_RS11480	COG2814	Major facilitator Superfamily
GCU45_RS11495	COG2378	regulation of single-species biofilm formation
GCU45_RS11500	COG1309	transcriptional regulator
GCU45_RS11520	COG4221	oxidoreductase activity
GCU45_RS11530	COG1595	DNA-templated transcription, initiation
GCU45_RS11555	COG2814	Major facilitator Superfamily
GCU45_RS11585	COG0346	lactoylglutathione lyase activity
GCU45_RS11595	COG1673	EVE domain
GCU45_RS11615	COG0667	Aldo Keto reductase
GCU45_RS11620	COG4124	Belongs to the glycosyl hydrolase 26 family
GCU45_RS11625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GCU45_RS11635	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCU45_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS11665	COG1595	DNA-templated transcription, initiation
GCU45_RS11670	COG0492	ferredoxin-NADP+ reductase activity
GCU45_RS11675	COG1794	racemase activity, acting on amino acids and derivatives
GCU45_RS11685	COG0395	ABC-type sugar transport system, permease component
GCU45_RS11690	COG1175	transmembrane transport
GCU45_RS11695	COG1653	transport
GCU45_RS11725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCU45_RS11730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCU45_RS11735	COG0596	Alpha beta hydrolase
GCU45_RS11745	COG2207	Transcriptional regulator
GCU45_RS11760	COG2814	Major facilitator Superfamily
GCU45_RS11775	COG1733	regulation of RNA biosynthetic process
GCU45_RS11785	COG2971	BadF BadG BcrA BcrD
GCU45_RS11790	COG0165	Argininosuccinate lyase
GCU45_RS11805	COG3842	ATPase activity
GCU45_RS11820	COG1361	Conserved repeat domain
GCU45_RS11825	COG0589	response to stress
GCU45_RS11830	COG2807	transmembrane transport
GCU45_RS11840	COG0596	Alpha beta hydrolase
GCU45_RS11845	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GCU45_RS11870	COG0656	L-ascorbic acid biosynthetic process
GCU45_RS11875	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCU45_RS11880	COG1309	transcriptional regulator
GCU45_RS11885	COG0604	alcohol dehydrogenase
GCU45_RS11900	COG2207	Transcriptional regulator
GCU45_RS11905	COG1653	transport
GCU45_RS11910	COG0395	ABC-type sugar transport system, permease component
GCU45_RS11915	COG4209	transmembrane transport
GCU45_RS11950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GCU45_RS11960	COG1396	sequence-specific DNA binding
GCU45_RS12040	COG4974	Belongs to the 'phage' integrase family
GCU45_RS12045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GCU45_RS12050	COG1061	Type III restriction enzyme res subunit
GCU45_RS12055	COG1002	Type II restriction enzyme, methylase subunits
GCU45_RS12145	COG0210	DNA helicase
GCU45_RS12165	COG1653	transport
GCU45_RS12175	COG0395	ABC-type sugar transport system, permease component
GCU45_RS12180	COG4209	transmembrane transport
GCU45_RS12195	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS12225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCU45_RS12295	COG4221	oxidoreductase activity
GCU45_RS12295	COG3321	synthase
GCU45_RS12295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCU45_RS12295	COG0604	alcohol dehydrogenase
GCU45_RS12300	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS12305	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS12320	COG0572	uridine kinase
GCU45_RS12325	COG4221	oxidoreductase activity
GCU45_RS12330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCU45_RS12335	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GCU45_RS12340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCU45_RS12345	COG4221	oxidoreductase activity
GCU45_RS12355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCU45_RS12395	COG0395	ABC-type sugar transport system, permease component
GCU45_RS12400	COG4209	transmembrane transport
GCU45_RS12420	COG0456	acetyltransferase
GCU45_RS12420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GCU45_RS12465	COG0494	nUDIX hydrolase
GCU45_RS12480	COG2207	Transcriptional regulator
GCU45_RS12490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCU45_RS12505	COG1309	transcriptional regulator
GCU45_RS12535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCU45_RS12555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GCU45_RS12560	COG1597	lipid kinase activity
GCU45_RS12570	COG4496	protein, YerC YecD
GCU45_RS12585	COG0598	Magnesium transport protein CorA
GCU45_RS12590	COG0306	phosphate transporter
GCU45_RS12595	COG1392	Phosphate transport regulator
GCU45_RS12600	COG1470	cell adhesion involved in biofilm formation
GCU45_RS12610	COG3384	dioxygenase
GCU45_RS12640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GCU45_RS12650	COG3402	PFAM membrane-flanked domain
GCU45_RS12660	COG0655	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS12675	COG0697	spore germination
GCU45_RS12685	COG0400	carboxylic ester hydrolase activity
GCU45_RS12690	COG0346	lactoylglutathione lyase activity
GCU45_RS12695	COG0151	Belongs to the GarS family
GCU45_RS12705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GCU45_RS12710	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GCU45_RS12715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GCU45_RS12720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GCU45_RS12725	COG0047	phosphoribosylformylglycinamidine synthase activity
GCU45_RS12730	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GCU45_RS12735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GCU45_RS12740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GCU45_RS12745	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GCU45_RS12750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GCU45_RS12755	COG0589	response to stress
GCU45_RS12760	COG3326	Membrane
GCU45_RS12780	COG5002	protein histidine kinase activity
GCU45_RS12810	COG2814	Major facilitator Superfamily
GCU45_RS12835	COG2252	PERMEase
GCU45_RS12845	COG1305	Transglutaminase-like
GCU45_RS12855	COG0714	Associated with various cellular activities
GCU45_RS12865	COG0586	Pfam SNARE associated Golgi protein
GCU45_RS12870	COG2814	Major facilitator Superfamily
GCU45_RS12880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GCU45_RS12885	COG1316	TRANSCRIPTIONal
GCU45_RS12905	COG1175	transmembrane transport
GCU45_RS12920	COG0180	Tryptophanyl-tRNA synthetase
GCU45_RS12925	COG0583	DNA-binding transcription factor activity
GCU45_RS12940	COG2207	Transcriptional regulator
GCU45_RS12940	COG4753	response regulator
GCU45_RS12940	COG4753	response regulator
GCU45_RS12940	COG2207	Transcriptional regulator
GCU45_RS12950	COG2972	Histidine kinase
GCU45_RS12955	COG0395	ABC-type sugar transport system, permease component
GCU45_RS12965	COG1653	transport
GCU45_RS12975	COG0483	inositol monophosphate 1-phosphatase activity
GCU45_RS12980	COG4294	response to UV
GCU45_RS12990	COG1181	Belongs to the D-alanine--D-alanine ligase family
GCU45_RS13000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GCU45_RS13005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GCU45_RS13010	COG2252	PERMEase
GCU45_RS13015	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GCU45_RS13030	COG1695	Transcriptional regulator
GCU45_RS13045	COG1073	alpha beta
GCU45_RS13050	COG1506	peptidase
GCU45_RS13050	COG4946	Tricorn protease homolog
GCU45_RS13050	COG0823	Involved in the tonB-independent uptake of proteins
GCU45_RS13055	COG1414	Transcriptional regulator
GCU45_RS13065	COG0302	gtp cyclohydrolase
GCU45_RS13080	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GCU45_RS13105	COG0736	holo-[acyl-carrier-protein] synthase activity
GCU45_RS13110	COG1874	Beta-galactosidase
GCU45_RS13120	COG0395	ABC-type sugar transport system, permease component
GCU45_RS13125	COG4209	transmembrane transport
GCU45_RS13150	COG3794	PFAM blue (type 1) copper domain protein
GCU45_RS13175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GCU45_RS13190	COG2207	Transcriptional regulator
GCU45_RS13195	COG2972	Histidine kinase
GCU45_RS13200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GCU45_RS13210	COG5002	protein histidine kinase activity
GCU45_RS13215	COG2081	HI0933 family
GCU45_RS13220	COG2070	2-Nitropropane dioxygenase
GCU45_RS13230	COG1131	(ABC) transporter
GCU45_RS13235	COG1619	proteins homologs of microcin C7 resistance protein MccF
GCU45_RS13240	COG0477	Major facilitator Superfamily
GCU45_RS13245	COG1122	ATPase activity
GCU45_RS13250	COG4721	ABC-type cobalt transport system, permease component
GCU45_RS13255	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GCU45_RS13265	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GCU45_RS13290	COG1956	GAF domain-containing protein
GCU45_RS13310	COG1193	negative regulation of DNA recombination
GCU45_RS13315	COG0366	Alpha amylase catalytic
GCU45_RS13335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCU45_RS13345	COG2271	Major facilitator Superfamily
GCU45_RS13350	COG0277	FAD linked oxidase domain protein
GCU45_RS13365	COG1199	ATP-dependent helicase activity
GCU45_RS13370	COG0628	permease
GCU45_RS13375	COG1253	flavin adenine dinucleotide binding
GCU45_RS13385	COG2814	Major facilitator Superfamily
GCU45_RS13405	COG0395	ABC-type sugar transport system, permease component
GCU45_RS13410	COG4209	transmembrane transport
GCU45_RS13425	COG0783	Belongs to the Dps family
GCU45_RS13450	COG1285	pathogenesis
GCU45_RS13455	COG1349	DNA-binding transcription factor activity
GCU45_RS13460	COG1063	alcohol dehydrogenase
GCU45_RS13485	COG0584	glycerophosphoryl diester phosphodiesterase
GCU45_RS13500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCU45_RS13505	COG0673	inositol 2-dehydrogenase activity
GCU45_RS13515	COG3708	Transcriptional regulator
GCU45_RS13515	COG2207	Transcriptional regulator
GCU45_RS13525	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS13525	COG2207	Transcriptional regulator
GCU45_RS13530	COG1609	Transcriptional regulator
GCU45_RS13540	COG3275	phosphorelay sensor kinase activity
GCU45_RS13545	COG2207	Transcriptional regulator
GCU45_RS13545	COG4753	response regulator
GCU45_RS13580	COG0395	ABC-type sugar transport system, permease component
GCU45_RS13595	COG3842	ATPase activity
GCU45_RS13610	COG4948	Mandelate Racemase Muconate Lactonizing
GCU45_RS13615	COG0383	alpha-mannosidase activity
GCU45_RS13620	COG0395	ABC-type sugar transport system, permease component
GCU45_RS13625	COG1175	transmembrane transport
GCU45_RS13635	COG1609	Transcriptional regulator
GCU45_RS13640	COG3507	Belongs to the glycosyl hydrolase 43 family
GCU45_RS13675	COG1668	transmembrane transport
GCU45_RS13680	COG4152	abc transporter atp-binding protein
GCU45_RS13685	COG1131	(ABC) transporter
GCU45_RS13710	COG3336	cytochrome c oxidase
GCU45_RS13715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GCU45_RS13720	COG1845	cytochrome c oxidase, subunit III
GCU45_RS13725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCU45_RS13730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GCU45_RS13730	COG2010	Cytochrome c
GCU45_RS13775	COG1970	mechanosensitive ion channel activity
GCU45_RS13800	COG0210	DNA helicase
GCU45_RS13810	COG2357	RelA SpoT domain protein
GCU45_RS13815	COG1876	peptidase activity
GCU45_RS13825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GCU45_RS13835	COG2182	Extracellular solute-binding protein
GCU45_RS13850	COG2972	Histidine kinase
GCU45_RS13855	COG2207	Transcriptional regulator
GCU45_RS13855	COG4753	response regulator
GCU45_RS13880	COG0251	oxidation-reduction process
GCU45_RS13890	COG3237	CsbD-like
GCU45_RS13895	COG1725	Transcriptional regulator
GCU45_RS13900	COG1131	(ABC) transporter
GCU45_RS13910	COG1131	(ABC) transporter
GCU45_RS13920	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GCU45_RS13925	COG0726	polysaccharide deacetylase
GCU45_RS13925	COG1649	PFAM Uncharacterised BCR, COG1649
GCU45_RS13930	COG1376	ErfK ybiS ycfS ynhG family protein
GCU45_RS13935	COG1705	Flagellar rod assembly protein muramidase FlgJ
GCU45_RS13940	COG0454	-acetyltransferase
GCU45_RS13945	COG0659	secondary active sulfate transmembrane transporter activity
GCU45_RS13955	COG4106	trans-aconitate 2-methyltransferase activity
GCU45_RS13970	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GCU45_RS13980	COG1683	Conserved Protein
GCU45_RS13985	COG5577	PFAM Coat F domain
GCU45_RS13990	COG0038	chloride channel
GCU45_RS13995	COG0517	IMP dehydrogenase activity
GCU45_RS14015	COG0011	TIGRFAM Protein of
GCU45_RS14020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCU45_RS14025	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCU45_RS14045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GCU45_RS14055	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GCU45_RS14065	COG0829	nickel cation binding
GCU45_RS14070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GCU45_RS14075	COG0830	nickel cation binding
GCU45_RS14080	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GCU45_RS14085	COG0804	urea catabolic process
GCU45_RS14090	COG0832	Belongs to the urease beta subunit family
GCU45_RS14095	COG0831	urea catabolic process
GCU45_RS14100	COG4413	Urea transporter
GCU45_RS14110	COG1131	(ABC) transporter
GCU45_RS14115	COG2205	protein histidine kinase activity
GCU45_RS14120	COG0745	RESPONSE REGULATOR receiver
GCU45_RS14130	COG3507	Belongs to the glycosyl hydrolase 43 family
GCU45_RS14150	COG2972	Histidine kinase
GCU45_RS14160	COG0395	ABC-type sugar transport system, permease component
GCU45_RS14165	COG1175	transmembrane transport
GCU45_RS14175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GCU45_RS14175	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GCU45_RS14180	COG2910	NAD(P)H-binding
GCU45_RS14185	COG2323	membrane
GCU45_RS14190	COG1285	pathogenesis
GCU45_RS14205	COG4208	sulfate ABC transporter
GCU45_RS14225	COG2706	6-phosphogluconolactonase activity
GCU45_RS14240	COG2116	formate transmembrane transporter activity
GCU45_RS14245	COG2146	nitrite reductase [NAD(P)H] activity
GCU45_RS14250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCU45_RS14255	COG3707	response regulator
GCU45_RS14260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GCU45_RS14280	COG0500	methyltransferase
GCU45_RS14295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCU45_RS14300	COG1309	transcriptional regulator
GCU45_RS14305	COG4846	Membrane protein involved in cytochrome C biogenesis
GCU45_RS14315	COG1252	NADH dehydrogenase
GCU45_RS14320	COG1289	transmembrane transporter activity
GCU45_RS14345	COG0154	amidase activity
GCU45_RS14350	COG0346	lactoylglutathione lyase activity
GCU45_RS14355	COG0454	-acetyltransferase
GCU45_RS14360	COG0494	nUDIX hydrolase
GCU45_RS14380	COG3766	membrane
GCU45_RS14405	COG1737	Transcriptional regulator
GCU45_RS14425	COG1131	(ABC) transporter
GCU45_RS14430	COG1725	Transcriptional regulator
GCU45_RS14435	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GCU45_RS14440	COG1131	(ABC) transporter
GCU45_RS14455	COG0395	ABC-type sugar transport system, permease component
GCU45_RS14460	COG4209	transmembrane transport
GCU45_RS14465	COG1609	Transcriptional regulator
GCU45_RS14475	COG0395	ABC-type sugar transport system, permease component
GCU45_RS14480	COG1175	transmembrane transport
GCU45_RS14500	COG0395	ABC-type sugar transport system, permease component
GCU45_RS14505	COG1175	transmembrane transport
GCU45_RS14525	COG2972	Histidine kinase
GCU45_RS14540	COG2188	Transcriptional regulator
GCU45_RS14565	COG0642	Histidine kinase
GCU45_RS14570	COG0745	RESPONSE REGULATOR receiver
GCU45_RS14590	COG1131	(ABC) transporter
GCU45_RS14600	COG2197	response regulator
GCU45_RS14620	COG1968	undecaprenyl-diphosphatase activity
GCU45_RS14625	COG0586	Pfam SNARE associated Golgi protein
GCU45_RS14630	COG0577	efflux transmembrane transporter activity
GCU45_RS14635	COG1136	(ABC) transporter
GCU45_RS14640	COG2205	protein histidine kinase activity
GCU45_RS14645	COG0745	RESPONSE REGULATOR receiver
GCU45_RS14665	COG0765	amino acid transport
GCU45_RS14670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU45_RS14675	COG1309	transcriptional regulator
GCU45_RS14705	COG3833	ABC-type maltose transport systems, permease component
GCU45_RS14710	COG1175	transmembrane transport
GCU45_RS14715	COG2182	Extracellular solute-binding protein
GCU45_RS14725	COG1609	Transcriptional regulator
GCU45_RS14730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCU45_RS14735	COG1554	hydrolase, family 65, central catalytic
GCU45_RS14740	COG1309	transcriptional regulator
GCU45_RS14750	COG0737	Belongs to the 5'-nucleotidase family
GCU45_RS14755	COG3871	stress protein (general stress protein 26)
GCU45_RS14775	COG0346	lactoylglutathione lyase activity
GCU45_RS14780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCU45_RS14790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU45_RS14795	COG1116	anion transmembrane transporter activity
GCU45_RS14800	COG0084	hydrolase, TatD family'
GCU45_RS14820	COG1064	alcohol dehydrogenase
GCU45_RS14825	COG0789	Transcriptional regulator
GCU45_RS14830	COG2217	Heavy metal translocating P-type atpase
GCU45_RS14835	COG2608	mercury ion transmembrane transporter activity
GCU45_RS14845	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GCU45_RS14845	COG2199	diguanylate cyclase activity
GCU45_RS14850	COG1276	copper resistance
GCU45_RS14850	COG2372	response to copper ion
GCU45_RS14855	COG4549	nuclear export factor GLE1
GCU45_RS14860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCU45_RS14865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU45_RS14870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU45_RS14885	COG1278	Cold shock
GCU45_RS14890	COG1126	abc transporter atp-binding protein
GCU45_RS14895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU45_RS14900	COG0765	amino acid transport
GCU45_RS14905	COG0765	amino acid transport
GCU45_RS14950	COG0477	Major facilitator Superfamily
GCU45_RS14970	COG3973	AAA domain
GCU45_RS14975	COG0783	Belongs to the Dps family
GCU45_RS14980	COG1733	regulation of RNA biosynthetic process
GCU45_RS14990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCU45_RS15005	COG0534	Mate efflux family protein
GCU45_RS15020	COG1653	transport
GCU45_RS15025	COG0395	ABC-type sugar transport system, permease component
GCU45_RS15030	COG4209	transmembrane transport
GCU45_RS15035	COG2207	Transcriptional regulator
GCU45_RS15045	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GCU45_RS15050	COG0363	glucosamine-6-phosphate deaminase activity
GCU45_RS15060	COG0673	inositol 2-dehydrogenase activity
GCU45_RS15065	COG0673	inositol 2-dehydrogenase activity
GCU45_RS15070	COG1737	Transcriptional regulator
GCU45_RS15095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCU45_RS15105	COG0395	ABC-type sugar transport system, permease component
GCU45_RS15110	COG1175	transmembrane transport
GCU45_RS15120	COG2972	Histidine kinase
GCU45_RS15125	COG2204	response regulator
GCU45_RS15140	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GCU45_RS15195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCU45_RS15200	COG4932	domain protein
GCU45_RS15200	COG5492	domain, Protein
GCU45_RS15205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCU45_RS15210	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GCU45_RS15215	COG0534	Mate efflux family protein
GCU45_RS15225	COG1175	transmembrane transport
GCU45_RS15230	COG0395	ABC-type sugar transport system, permease component
GCU45_RS15240	COG1609	Transcriptional regulator
GCU45_RS15250	COG1486	melibiose metabolic process
GCU45_RS15255	COG2814	Major facilitator Superfamily
GCU45_RS15260	COG0395	ABC-type sugar transport system, permease component
GCU45_RS15265	COG1175	transmembrane transport
GCU45_RS15280	COG2972	Histidine kinase
GCU45_RS15295	COG1609	Transcriptional regulator
GCU45_RS15310	COG0745	RESPONSE REGULATOR receiver
GCU45_RS15315	COG2205	protein histidine kinase activity
GCU45_RS15320	COG1136	(ABC) transporter
GCU45_RS15325	COG0577	efflux transmembrane transporter activity
GCU45_RS15330	COG5337	Spore coat protein CotH
GCU45_RS15345	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GCU45_RS15355	COG2909	trisaccharide binding
GCU45_RS15360	COG5002	protein histidine kinase activity
GCU45_RS15365	COG0745	RESPONSE REGULATOR receiver
GCU45_RS15375	COG1131	(ABC) transporter
GCU45_RS15380	COG1132	(ABC) transporter
GCU45_RS15385	COG1132	(ABC) transporter
GCU45_RS15400	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS15400	COG2207	Transcriptional regulator
GCU45_RS15405	COG2223	nitrite transmembrane transporter activity
GCU45_RS15420	COG1486	melibiose metabolic process
GCU45_RS15425	COG2207	Transcriptional regulator
GCU45_RS15450	COG0395	ABC-type sugar transport system, permease component
GCU45_RS15455	COG4209	transmembrane transport
GCU45_RS15460	COG2207	Transcriptional regulator
GCU45_RS15470	COG1522	sequence-specific DNA binding
GCU45_RS15485	COG4191	Histidine kinase
GCU45_RS15490	COG1737	Transcriptional regulator
GCU45_RS15495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCU45_RS15510	COG2814	Major facilitator Superfamily
GCU45_RS15515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GCU45_RS15520	COG0586	Pfam SNARE associated Golgi protein
GCU45_RS15525	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GCU45_RS15535	COG0745	RESPONSE REGULATOR receiver
GCU45_RS15545	COG2197	response regulator
GCU45_RS15550	COG4585	Histidine kinase
GCU45_RS15555	COG3239	Fatty acid desaturase
GCU45_RS15565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCU45_RS15570	COG3693	PFAM glycoside hydrolase, family 10
GCU45_RS15575	COG3458	cephalosporin-C deacetylase activity
GCU45_RS15580	COG0572	uridine kinase
GCU45_RS15585	COG3394	polysaccharide catabolic process
GCU45_RS15600	COG1132	(ABC) transporter
GCU45_RS15610	COG1132	(ABC) transporter
GCU45_RS15620	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GCU45_RS15625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GCU45_RS15630	COG1733	regulation of RNA biosynthetic process
GCU45_RS15655	COG1316	TRANSCRIPTIONal
GCU45_RS15660	COG1388	LysM domain
GCU45_RS15675	COG0346	lactoylglutathione lyase activity
GCU45_RS15695	COG1178	ABC-type Fe3 transport system permease component
GCU45_RS15700	COG3842	ATPase activity
GCU45_RS15705	COG0583	DNA-binding transcription factor activity
GCU45_RS15720	COG1349	DNA-binding transcription factor activity
GCU45_RS15725	COG0534	Mate efflux family protein
GCU45_RS15755	COG1181	Belongs to the D-alanine--D-alanine ligase family
GCU45_RS15775	COG1695	Transcriptional regulator
GCU45_RS15785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU45_RS15795	COG1104	cysteine desulfurase activity
GCU45_RS15800	COG0477	Major facilitator Superfamily
GCU45_RS15810	COG0446	pyridine nucleotide-disulphide oxidoreductase
GCU45_RS15820	COG2378	regulation of single-species biofilm formation
GCU45_RS15825	COG0596	Alpha beta hydrolase
GCU45_RS15880	COG0640	Transcriptional regulator
GCU45_RS15885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GCU45_RS15905	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GCU45_RS15925	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS15925	COG2207	Transcriptional regulator
GCU45_RS15930	COG4886	Leucine-rich repeat (LRR) protein
GCU45_RS15940	COG3279	Response regulator of the LytR AlgR family
GCU45_RS15945	COG2972	Histidine kinase
GCU45_RS15945	COG0745	RESPONSE REGULATOR receiver
GCU45_RS15965	COG1278	Cold shock
GCU45_RS15975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GCU45_RS15980	COG0557	exoribonuclease II activity
GCU45_RS15985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCU45_RS15990	COG0148	phosphopyruvate hydratase activity
GCU45_RS15995	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GCU45_RS16000	COG0149	triose-phosphate isomerase activity
GCU45_RS16025	COG0740	serine-type endopeptidase activity
GCU45_RS16035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCU45_RS16040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCU45_RS16045	COG0477	Major facilitator Superfamily
GCU45_RS16055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GCU45_RS16060	COG1177	transmembrane transport
GCU45_RS16065	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCU45_RS16085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCU45_RS16090	COG1481	regulation of sporulation
GCU45_RS16095	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GCU45_RS16100	COG1660	Displays ATPase and GTPase activities
GCU45_RS16105	COG1940	carbohydrate kinase activity
GCU45_RS16110	COG1131	(ABC) transporter
GCU45_RS16115	COG0842	Transport permease protein
GCU45_RS16125	COG2197	response regulator
GCU45_RS16130	COG1396	sequence-specific DNA binding
GCU45_RS16155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GCU45_RS16160	COG0140	phosphoribosyl-ATP diphosphatase activity
GCU45_RS16160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GCU45_RS16165	COG0107	imidazoleglycerol-phosphate synthase activity
GCU45_RS16170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GCU45_RS16175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GCU45_RS16180	COG0131	Imidazoleglycerol-phosphate dehydratase
GCU45_RS16185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GCU45_RS16190	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GCU45_RS16195	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GCU45_RS16205	COG0546	phosphoglycolate phosphatase activity
GCU45_RS16210	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GCU45_RS16220	COG3842	ATPase activity
GCU45_RS16225	COG2508	Transcriptional regulator
GCU45_RS16305	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GCU45_RS16310	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GCU45_RS16330	COG0254	rRNA binding
GCU45_RS16340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GCU45_RS16345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GCU45_RS16355	COG2204	response regulator
GCU45_RS16360	COG0504	CTP synthase activity
GCU45_RS16365	COG3343	RNA polymerase activity
GCU45_RS16375	COG0018	arginyl-trna synthetase
GCU45_RS16390	COG1175	transmembrane transport
GCU45_RS16395	COG0395	ABC-type sugar transport system, permease component
GCU45_RS16400	COG2972	Histidine kinase
GCU45_RS16405	COG2207	Transcriptional regulator
GCU45_RS16410	COG1653	transport
GCU45_RS16420	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GCU45_RS16425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCU45_RS16430	COG2094	Belongs to the DNA glycosylase MPG family
GCU45_RS16450	COG1388	LysM domain
GCU45_RS16450	COG3103	Sh3 type 3 domain protein
GCU45_RS16450	COG0791	NLP P60 protein
GCU45_RS16455	COG0791	NLP P60 protein
GCU45_RS16480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GCU45_RS16485	COG1360	Flagellar Motor Protein
GCU45_RS16490	COG1187	pseudouridine synthase activity
GCU45_RS16495	COG5002	protein histidine kinase activity
GCU45_RS16500	COG0590	tRNA wobble adenosine to inosine editing
GCU45_RS16525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GCU45_RS16540	COG1686	Belongs to the peptidase S11 family
GCU45_RS16545	COG0517	IMP dehydrogenase activity
GCU45_RS16545	COG0516	GMP reductase activity
GCU45_RS16570	COG3226	Transcriptional regulator
GCU45_RS16580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCU45_RS16585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCU45_RS16590	COG1396	sequence-specific DNA binding
GCU45_RS16595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GCU45_RS16600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GCU45_RS16605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GCU45_RS16610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCU45_RS16615	COG0512	Glutamine amidotransferase of anthranilate synthase
GCU45_RS16620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GCU45_RS16625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GCU45_RS16630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCU45_RS16635	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GCU45_RS16645	COG0157	Belongs to the NadC ModD family
GCU45_RS16650	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GCU45_RS16655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GCU45_RS16660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GCU45_RS16675	COG0515	serine threonine protein kinase
GCU45_RS16680	COG2304	oxidoreductase activity
GCU45_RS16685	COG2208	phosphoserine phosphatase activity
GCU45_RS16690	COG1098	S1 RNA binding domain
GCU45_RS16710	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GCU45_RS16720	COG3956	TIGRFAM MazG family protein
GCU45_RS16725	COG2244	polysaccharide biosynthetic process
GCU45_RS16730	COG2002	toxin-antitoxin pair type II binding
GCU45_RS16735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCU45_RS16740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GCU45_RS16760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GCU45_RS16765	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GCU45_RS16770	COG2088	sporulation resulting in formation of a cellular spore
GCU45_RS16775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GCU45_RS16780	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GCU45_RS16790	COG4466	Protein conserved in bacteria
GCU45_RS16800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GCU45_RS16810	COG3584	3D domain protein
GCU45_RS16810	COG3583	domain protein
GCU45_RS16815	COG0084	hydrolase, TatD family'
GCU45_RS16820	COG1078	dGTPase activity
GCU45_RS16825	COG2002	toxin-antitoxin pair type II binding
GCU45_RS16830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GCU45_RS16835	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GCU45_RS16840	COG4467	Involved in initiation control of chromosome replication
GCU45_RS16845	COG1774	PSP1 C-terminal conserved region
GCU45_RS16850	COG0470	DNA polymerase III
GCU45_RS16855	COG1728	Protein conserved in bacteria
GCU45_RS16860	COG3870	Protein conserved in bacteria
GCU45_RS16865	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GCU45_RS16870	COG1982	Orn Lys Arg decarboxylase major
GCU45_RS16905	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GCU45_RS16910	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GCU45_RS16915	COG1181	Belongs to the D-alanine--D-alanine ligase family
GCU45_RS16920	COG0187	DNA topoisomerase II activity
GCU45_RS16935	COG2501	S4 domain
GCU45_RS16940	COG0592	DNA-directed DNA polymerase activity
GCU45_RS16945	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GCU45_RS16950	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GCU45_RS16955	COG0594	ribonuclease P activity
GCU45_RS16965	COG1847	R3H domain protein
GCU45_RS16970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GCU45_RS16975	COG0445	tRNA wobble uridine modification
GCU45_RS16985	COG1475	DNA binding
GCU45_RS16990	COG1192	Involved in chromosome partitioning
GCU45_RS16995	COG1475	DNA binding
GCU45_RS17000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GCU45_RS17020	COG0668	transmembrane transport
GCU45_RS17025	COG4481	Protein conserved in bacteria
GCU45_RS17040	COG0360	Binds together with S18 to 16S ribosomal RNA
GCU45_RS17045	COG0629	single-stranded DNA binding
GCU45_RS17050	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GCU45_RS17055	COG2972	Histidine kinase
GCU45_RS17065	COG1653	transport
GCU45_RS17070	COG4209	transmembrane transport
GCU45_RS17075	COG0395	ABC-type sugar transport system, permease component
GCU45_RS17080	COG1472	Belongs to the glycosyl hydrolase 3 family
GCU45_RS17085	COG0383	alpha-mannosidase activity
GCU45_RS17100	COG0383	alpha-mannosidase activity
GCU45_RS17110	COG0601	transmembrane transport
GCU45_RS17115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU45_RS17120	COG0444	Belongs to the ABC transporter superfamily
GCU45_RS17125	COG4608	Belongs to the ABC transporter superfamily
GCU45_RS17130	COG1316	TRANSCRIPTIONal
GCU45_RS17150	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GCU45_RS17155	COG0359	binds to the 23S rRNA
GCU45_RS17160	COG0305	Participates in initiation and elongation during chromosome replication
GCU45_RS17165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GCU45_RS17175	COG0739	heme binding
GCU45_RS17175	COG1196	nuclear chromosome segregation
GCU45_RS17175	COG0741	lytic transglycosylase activity
GCU45_RS17180	COG0745	RESPONSE REGULATOR receiver
GCU45_RS17185	COG5002	protein histidine kinase activity
GCU45_RS17200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GCU45_RS17210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCU45_RS17230	COG1959	2 iron, 2 sulfur cluster binding
GCU45_RS17255	COG0737	Belongs to the 5'-nucleotidase family
GCU45_RS17255	COG1525	nuclease
GCU45_RS17255	COG4085	toxin activity
GCU45_RS17260	COG1733	regulation of RNA biosynthetic process
GCU45_RS17265	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS17275	COG4509	Sortase family
GCU45_RS17290	COG4941	Belongs to the sigma-70 factor family
GCU45_RS17310	COG1309	transcriptional regulator
GCU45_RS17320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GCU45_RS17330	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS17345	COG0778	Nitroreductase
GCU45_RS17350	COG2211	Major facilitator Superfamily
GCU45_RS17355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GCU45_RS17370	COG1361	Conserved repeat domain
GCU45_RS17370	COG2911	Protein conserved in bacteria
GCU45_RS17370	COG3266	domain, Protein
GCU45_RS17380	COG4221	oxidoreductase activity
GCU45_RS17385	COG1309	transcriptional regulator
GCU45_RS17395	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS17400	COG1733	regulation of RNA biosynthetic process
GCU45_RS17420	COG1733	regulation of RNA biosynthetic process
GCU45_RS17450	COG2318	DinB family
GCU45_RS17460	COG0805	protein transport
GCU45_RS17465	COG0789	Transcriptional regulator
GCU45_RS17480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCU45_RS17485	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GCU45_RS17495	COG0583	DNA-binding transcription factor activity
GCU45_RS17510	COG0745	RESPONSE REGULATOR receiver
GCU45_RS17560	COG0640	Transcriptional regulator
GCU45_RS17565	COG0431	NADPH-dependent FMN reductase
GCU45_RS17580	COG4221	oxidoreductase activity
GCU45_RS17585	COG0789	Transcriptional regulator
GCU45_RS17590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU45_RS17610	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GCU45_RS17620	COG5002	protein histidine kinase activity
GCU45_RS17625	COG2207	Transcriptional regulator
GCU45_RS17625	COG4753	response regulator
GCU45_RS17630	COG2814	Major facilitator Superfamily
GCU45_RS17645	COG1595	DNA-templated transcription, initiation
GCU45_RS17650	COG0385	Bile acid
GCU45_RS17675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GCU45_RS17715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GCU45_RS17740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCU45_RS17745	COG0318	PFAM AMP-dependent synthetase and ligase
GCU45_RS17755	COG0583	DNA-binding transcription factor activity
GCU45_RS17760	COG1473	amidohydrolase
GCU45_RS17765	COG1288	antiporter activity
GCU45_RS17770	COG0697	spore germination
GCU45_RS17775	COG0667	Aldo Keto reductase
GCU45_RS17780	COG3069	C4-dicarboxylate transmembrane transporter activity
GCU45_RS17785	COG0531	amino acid
GCU45_RS17790	COG0488	(ABC) transporter
GCU45_RS17800	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS17805	COG1733	regulation of RNA biosynthetic process
GCU45_RS17810	COG2207	Transcriptional regulator
GCU45_RS17830	COG0789	Transcriptional regulator
GCU45_RS17840	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GCU45_RS17855	COG4335	DNA alkylation repair
GCU45_RS17865	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GCU45_RS17870	COG2363	Small membrane protein
GCU45_RS17880	COG0714	Associated with various cellular activities
GCU45_RS17895	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GCU45_RS17900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GCU45_RS17905	COG1733	regulation of RNA biosynthetic process
GCU45_RS17915	COG1215	transferase activity, transferring glycosyl groups
GCU45_RS17925	COG3708	Transcriptional regulator
GCU45_RS17925	COG2207	Transcriptional regulator
GCU45_RS17930	COG1063	alcohol dehydrogenase
GCU45_RS17940	COG3695	enzyme binding
GCU45_RS17955	COG0789	Transcriptional regulator
GCU45_RS17955	COG4978	Transcriptional regulator
GCU45_RS17960	COG2814	Major facilitator Superfamily
GCU45_RS17985	COG0640	Transcriptional regulator
GCU45_RS17990	COG2130	NADP-dependent
GCU45_RS17995	COG0425	Belongs to the sulfur carrier protein TusA family
GCU45_RS18025	COG1940	carbohydrate kinase activity
GCU45_RS18030	COG1846	Transcriptional regulator
GCU45_RS18035	COG1289	transmembrane transporter activity
GCU45_RS18045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GCU45_RS18055	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GCU45_RS18065	COG2409	Drug exporters of the RND superfamily
GCU45_RS18065	COG1033	growth of symbiont in host cell
GCU45_RS18075	COG0640	Transcriptional regulator
GCU45_RS18080	COG0753	catalase activity
GCU45_RS18080	COG0693	protein deglycase activity
GCU45_RS18085	COG0392	lysyltransferase activity
GCU45_RS18085	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GCU45_RS18105	COG5002	protein histidine kinase activity
GCU45_RS18110	COG0745	RESPONSE REGULATOR receiver
GCU45_RS18125	COG0095	Lipoate-protein ligase
GCU45_RS18135	COG0463	Glycosyl transferase, family 2
GCU45_RS18150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCU45_RS18160	COG0686	Belongs to the AlaDH PNT family
GCU45_RS18165	COG2508	Transcriptional regulator
GCU45_RS18175	COG1132	(ABC) transporter
GCU45_RS18180	COG1132	(ABC) transporter
GCU45_RS18185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCU45_RS18190	COG0805	protein transport
GCU45_RS18210	COG1653	transport
GCU45_RS18215	COG1175	transmembrane transport
GCU45_RS18220	COG0395	ABC-type sugar transport system, permease component
GCU45_RS18225	COG0586	Pfam SNARE associated Golgi protein
GCU45_RS18235	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU45_RS18240	COG4605	iron ion homeostasis
GCU45_RS18245	COG4604	ABC transporter, ATP-binding protein
GCU45_RS18250	COG4607	ABC-type enterochelin transport system periplasmic component
GCU45_RS18265	COG0745	RESPONSE REGULATOR receiver
GCU45_RS18280	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS18300	COG1131	(ABC) transporter
GCU45_RS18330	COG1271	oxidase subunit
GCU45_RS18335	COG1294	oxidase, subunit
GCU45_RS18340	COG4988	ABC transporter
GCU45_RS18345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GCU45_RS18350	COG1309	transcriptional regulator
GCU45_RS18365	COG1785	Belongs to the alkaline phosphatase family
GCU45_RS18370	COG1113	amino acid transport
GCU45_RS18375	COG1280	lysine exporter protein (LysE YggA)
GCU45_RS18380	COG2814	Major facilitator Superfamily
GCU45_RS18385	COG1566	PFAM secretion protein HlyD family protein
GCU45_RS18390	COG0655	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS18405	COG1132	(ABC) transporter
GCU45_RS18410	COG1132	(ABC) transporter
GCU45_RS18420	COG1609	Transcriptional regulator
GCU45_RS18430	COG1368	sulfuric ester hydrolase activity
GCU45_RS18440	COG1199	ATP-dependent helicase activity
GCU45_RS18440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCU45_RS18445	COG0673	inositol 2-dehydrogenase activity
GCU45_RS18450	COG1346	cytolysis
GCU45_RS18455	COG1380	Effector of murein hydrolase LrgA
GCU45_RS18460	COG0583	DNA-binding transcription factor activity
GCU45_RS18465	COG0534	Mate efflux family protein
GCU45_RS18485	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GCU45_RS18490	COG1309	transcriptional regulator
GCU45_RS18500	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GCU45_RS18515	COG0723	plastoquinol--plastocyanin reductase activity
GCU45_RS18515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCU45_RS18520	COG0667	Aldo Keto reductase
GCU45_RS18530	COG1472	Belongs to the glycosyl hydrolase 3 family
GCU45_RS18535	COG2211	Major facilitator Superfamily
GCU45_RS18545	COG0789	Transcriptional regulator
GCU45_RS18550	COG0840	transmembrane signaling receptor activity
GCU45_RS18555	COG0697	spore germination
GCU45_RS18580	COG1587	Uroporphyrinogen-III synthase
GCU45_RS18595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GCU45_RS18605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS18610	COG2140	Oxalate decarboxylase
GCU45_RS18620	COG0386	Belongs to the glutathione peroxidase family
GCU45_RS18625	COG0702	epimerase
GCU45_RS18630	COG0243	molybdopterin cofactor binding
GCU45_RS18635	COG2814	Major facilitator Superfamily
GCU45_RS18645	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS18650	COG2258	MOSC domain
GCU45_RS18655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU45_RS18675	COG0746	molybdenum cofactor guanylyltransferase activity
GCU45_RS18680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCU45_RS18685	COG1309	transcriptional regulator
GCU45_RS18690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCU45_RS18695	COG2076	Multidrug Resistance protein
GCU45_RS18700	COG2076	Multidrug Resistance protein
GCU45_RS18710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCU45_RS18715	COG1120	ATPase activity
GCU45_RS18730	COG1304	FMN binding
GCU45_RS18735	COG4720	Psort location CytoplasmicMembrane, score
GCU45_RS18750	COG0012	GTP binding
GCU45_RS18775	COG0583	DNA-binding transcription factor activity
GCU45_RS18780	COG0531	amino acid
GCU45_RS18785	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GCU45_RS18795	COG0772	Belongs to the SEDS family
GCU45_RS18800	COG0772	Belongs to the SEDS family
GCU45_RS18810	COG0009	L-threonylcarbamoyladenylate synthase
GCU45_RS18815	COG1971	Probably functions as a manganese efflux pump
GCU45_RS18820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GCU45_RS18825	COG0698	ribose 5-phosphate isomerase
GCU45_RS18835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GCU45_RS18845	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GCU45_RS18860	COG0356	it plays a direct role in the translocation of protons across the membrane
GCU45_RS18875	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GCU45_RS18880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GCU45_RS18885	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GCU45_RS18890	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GCU45_RS18895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GCU45_RS18905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GCU45_RS18910	COG2385	sporulation resulting in formation of a cellular spore
GCU45_RS18920	COG1609	Transcriptional regulator
GCU45_RS18930	COG4786	Flagellar basal body rod
GCU45_RS18935	COG4786	Flagellar basal body rod
GCU45_RS18945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GCU45_RS18950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GCU45_RS18970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCU45_RS19005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GCU45_RS19010	COG3693	PFAM glycoside hydrolase, family 10
GCU45_RS19035	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GCU45_RS19040	COG1040	competence protein
GCU45_RS19060	COG4786	Flagellar basal body rod
GCU45_RS19060	COG1256	bacterial-type flagellum assembly
GCU45_RS19065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GCU45_RS19075	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GCU45_RS19080	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GCU45_RS19095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GCU45_RS19100	COG1516	flagellar protein fliS
GCU45_RS19110	COG1361	Conserved repeat domain
GCU45_RS19110	COG3266	domain, Protein
GCU45_RS19110	COG2911	Protein conserved in bacteria
GCU45_RS19120	COG1278	Cold shock
GCU45_RS19125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GCU45_RS19130	COG0653	protein targeting
GCU45_RS19140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GCU45_RS19145	COG2226	methyltransferase
GCU45_RS19150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GCU45_RS19155	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GCU45_RS19160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GCU45_RS19165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GCU45_RS19170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GCU45_RS19175	COG0137	argininosuccinate synthase activity
GCU45_RS19180	COG0165	Argininosuccinate lyase
GCU45_RS19185	COG0789	Transcriptional regulator
GCU45_RS19190	COG1664	Polymer-forming cytoskeletal
GCU45_RS19195	COG1664	Polymer-forming cytoskeletal
GCU45_RS19200	COG2814	Major facilitator Superfamily
GCU45_RS19205	COG0592	DNA-directed DNA polymerase activity
GCU45_RS19215	COG2720	vancomycin resistance protein
GCU45_RS19220	COG2884	Cell division ATP-binding protein ftsE
GCU45_RS19225	COG2177	Part of the ABC transporter FtsEX involved in
GCU45_RS19230	COG0739	heme binding
GCU45_RS19235	COG3409	Peptidoglycan-binding domain 1 protein
GCU45_RS19235	COG0793	Belongs to the peptidase S41A family
GCU45_RS19240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCU45_RS19250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GCU45_RS19255	COG0556	nucleotide-excision repair
GCU45_RS19260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCU45_RS19270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCU45_RS19280	COG0826	peptidase U32
GCU45_RS19295	COG1091	dTDP-4-dehydrorhamnose reductase activity
GCU45_RS19305	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GCU45_RS19310	COG0210	DNA helicase
GCU45_RS19315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GCU45_RS19325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCU45_RS19365	COG3880	PFAM UvrB UvrC protein
GCU45_RS19370	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GCU45_RS19375	COG0542	response to heat
GCU45_RS19380	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GCU45_RS19385	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GCU45_RS19390	COG1183	phosphatidylcholine synthase activity
GCU45_RS19400	COG4956	integral membrane protein (PIN domain superfamily)
GCU45_RS19405	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GCU45_RS19410	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GCU45_RS19415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCU45_RS19420	COG1045	serine acetyltransferase
GCU45_RS19425	COG0215	cysteine-tRNA ligase activity
GCU45_RS19430	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GCU45_RS19435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCU45_RS19440	COG3688	RNA-binding protein containing a PIN domain
GCU45_RS19450	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GCU45_RS19455	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCU45_RS19460	COG0250	Participates in transcription elongation, termination and antitermination
GCU45_RS19470	COG0081	regulation of translation
GCU45_RS19475	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GCU45_RS19480	COG0222	ribosome binding
GCU45_RS19485	COG2813	Specifically methylates the guanine in position
GCU45_RS19490	COG0085	RNA polymerase activity
GCU45_RS19495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GCU45_RS19500	COG1358	cellular component organization or biogenesis
GCU45_RS19505	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GCU45_RS19510	COG0049	tRNA binding
GCU45_RS19520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GCU45_RS19530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GCU45_RS19535	COG0088	Forms part of the polypeptide exit tunnel
GCU45_RS19540	COG0089	rRNA binding
GCU45_RS19545	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GCU45_RS19560	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GCU45_RS19565	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GCU45_RS19570	COG0255	Belongs to the universal ribosomal protein uL29 family
GCU45_RS19575	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GCU45_RS19580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GCU45_RS19585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GCU45_RS19590	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GCU45_RS19595	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GCU45_RS19600	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GCU45_RS19605	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GCU45_RS19610	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GCU45_RS19615	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GCU45_RS19620	COG1841	ribosomal large subunit assembly
GCU45_RS19625	COG0200	Binds to the 23S rRNA
GCU45_RS19630	COG0201	protein transport
GCU45_RS19635	COG0563	adenylate kinase activity
GCU45_RS19640	COG0024	Methionine aminopeptidase
GCU45_RS19650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GCU45_RS19655	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCU45_RS19660	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GCU45_RS19665	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GCU45_RS19670	COG0202	RNA polymerase activity
GCU45_RS19675	COG0203	ribosomal protein L17
GCU45_RS19680	COG0101	tRNA pseudouridine synthase activity
GCU45_RS19685	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GCU45_RS19690	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GCU45_RS19700	COG0175	sulfate reduction
GCU45_RS19705	COG2046	Belongs to the sulfate adenylyltransferase family
GCU45_RS19710	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCU45_RS19715	COG0489	protein tyrosine kinase activity
GCU45_RS19730	COG0726	polysaccharide deacetylase
GCU45_RS19830	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GCU45_RS19835	COG1595	DNA-templated transcription, initiation
GCU45_RS19840	COG5662	AntiSigma factor
GCU45_RS19845	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GCU45_RS19855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GCU45_RS19865	COG0583	DNA-binding transcription factor activity
GCU45_RS19870	COG0583	DNA-binding transcription factor activity
GCU45_RS19880	COG2972	Histidine kinase
GCU45_RS19885	COG4753	response regulator
GCU45_RS19885	COG2207	Transcriptional regulator
GCU45_RS19890	COG2267	carboxylic ester hydrolase activity
GCU45_RS19895	COG1335	isochorismatase
GCU45_RS19910	COG2814	Major facilitator Superfamily
GCU45_RS19920	COG0346	lactoylglutathione lyase activity
GCU45_RS19925	COG0753	catalase activity
GCU45_RS19940	COG1733	regulation of RNA biosynthetic process
GCU45_RS19945	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GCU45_RS19950	COG4260	virion core protein, lumpy skin disease virus
GCU45_RS19965	COG1132	(ABC) transporter
GCU45_RS19970	COG1846	Transcriptional regulator
GCU45_RS19975	COG2814	Major facilitator Superfamily
GCU45_RS19995	COG4715	Zinc finger, swim domain protein
GCU45_RS20010	COG0697	spore germination
GCU45_RS20015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS20025	COG0583	DNA-binding transcription factor activity
GCU45_RS20030	COG1942	4-Oxalocrotonate Tautomerase
GCU45_RS20035	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS20050	COG0667	Aldo Keto reductase
GCU45_RS20065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCU45_RS20070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GCU45_RS20085	COG1012	belongs to the aldehyde dehydrogenase family
GCU45_RS20090	COG1846	Transcriptional regulator
GCU45_RS20115	COG2217	Heavy metal translocating P-type atpase
GCU45_RS20135	COG0800	Aldolase
GCU45_RS20145	COG0833	amino acid
GCU45_RS20150	COG1413	lyase activity
GCU45_RS20160	COG0488	(ABC) transporter
GCU45_RS20170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GCU45_RS20215	COG2208	phosphoserine phosphatase activity
GCU45_RS20220	COG0784	Response regulator, receiver
GCU45_RS20220	COG2205	protein histidine kinase activity
GCU45_RS20220	COG5002	protein histidine kinase activity
GCU45_RS20225	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GCU45_RS20245	COG1191	sigma factor activity
GCU45_RS20250	COG0598	Magnesium transport protein CorA
GCU45_RS20260	COG1733	regulation of RNA biosynthetic process
GCU45_RS20265	COG1609	Transcriptional regulator
GCU45_RS20275	COG0395	ABC-type sugar transport system, permease component
GCU45_RS20280	COG4209	transmembrane transport
GCU45_RS20290	COG0673	inositol 2-dehydrogenase activity
GCU45_RS20305	COG2261	transglycosylase associated protein
GCU45_RS20315	COG1741	Belongs to the pirin family
GCU45_RS20355	COG0586	Pfam SNARE associated Golgi protein
GCU45_RS20365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCU45_RS20380	COG0154	amidase activity
GCU45_RS20385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GCU45_RS20390	COG0456	acetyltransferase
GCU45_RS20390	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GCU45_RS20395	COG1285	pathogenesis
GCU45_RS20410	COG0735	belongs to the Fur family
GCU45_RS20535	COG1842	Phage shock protein A
GCU45_RS20545	COG4585	Histidine kinase
GCU45_RS20550	COG2197	response regulator
GCU45_RS20565	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GCU45_RS20570	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GCU45_RS20580	COG0569	domain protein
GCU45_RS20585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCU45_RS20590	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS20595	COG1312	Catalyzes the dehydration of D-mannonate
GCU45_RS20620	COG0739	heme binding
GCU45_RS20625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GCU45_RS20630	COG4470	Protein conserved in bacteria
GCU45_RS20635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GCU45_RS20640	COG3314	Sporulation integral membrane protein YlbJ
GCU45_RS20655	COG3093	addiction module antidote protein HigA
GCU45_RS20705	COG0180	Tryptophanyl-tRNA synthetase
GCU45_RS20720	COG1988	membrane-bound metal-dependent
GCU45_RS20725	COG0109	protoheme IX farnesyltransferase activity
GCU45_RS20730	COG1999	signal sequence binding
GCU45_RS20735	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GCU45_RS20755	COG0737	Belongs to the 5'-nucleotidase family
GCU45_RS20765	COG1396	sequence-specific DNA binding
GCU45_RS20785	COG4824	toxin secretion phage lysis holin
GCU45_RS20790	COG1705	Flagellar rod assembly protein muramidase FlgJ
GCU45_RS20805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCU45_RS20810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCU45_RS20815	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GCU45_RS20820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS20840	COG3773	Cell wall hydrolase
GCU45_RS20845	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GCU45_RS20855	COG0070	glutamate synthase
GCU45_RS20855	COG0067	glutamate synthase
GCU45_RS20855	COG0069	glutamate synthase activity
GCU45_RS20860	COG1396	sequence-specific DNA binding
GCU45_RS20870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GCU45_RS20875	COG1316	TRANSCRIPTIONal
GCU45_RS20880	COG1131	(ABC) transporter
GCU45_RS20885	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GCU45_RS20895	COG0739	heme binding
GCU45_RS20900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCU45_RS20905	COG1742	UPF0060 membrane protein
GCU45_RS20910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GCU45_RS20915	COG1793	dna ligase
GCU45_RS20915	COG3285	dna ligase
GCU45_RS20920	COG1793	dna ligase
GCU45_RS20925	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GCU45_RS20950	COG0583	DNA-binding transcription factor activity
GCU45_RS20955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU45_RS20960	COG0765	amino acid transport
GCU45_RS20965	COG0765	amino acid transport
GCU45_RS20970	COG1126	abc transporter atp-binding protein
GCU45_RS20975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS20980	COG1473	amidohydrolase
GCU45_RS20995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS21000	COG1473	amidohydrolase
GCU45_RS21005	COG0431	NADPH-dependent FMN reductase
GCU45_RS21010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS21025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU45_RS21035	COG2814	Major facilitator Superfamily
GCU45_RS21040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS21065	COG0802	atpase or kinase
GCU45_RS21070	COG1214	PFAM Peptidase M22, glycoprotease
GCU45_RS21075	COG0456	acetyltransferase
GCU45_RS21080	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GCU45_RS21085	COG0488	(ABC) transporter
GCU45_RS21090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GCU45_RS21095	COG0315	cyclic pyranopterin monophosphate synthase activity
GCU45_RS21100	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCU45_RS21105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCU45_RS21110	COG0805	protein transport
GCU45_RS21115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GCU45_RS21120	COG0459	protein refolding
GCU45_RS21125	COG0248	Ppx GppA phosphatase
GCU45_RS21130	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GCU45_RS21150	COG2135	peptidase activity
GCU45_RS21170	COG2207	Transcriptional regulator
GCU45_RS21175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCU45_RS21175	COG0425	Belongs to the sulfur carrier protein TusA family
GCU45_RS21180	COG2210	Belongs to the sulfur carrier protein TusA family
GCU45_RS21185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCU45_RS21185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCU45_RS21190	COG0730	response to heat
GCU45_RS21195	COG1937	Protein conserved in bacteria
GCU45_RS21210	COG2755	lipolytic protein G-D-S-L family
GCU45_RS21210	COG0657	acetylesterase activity
GCU45_RS21215	COG0791	NLP P60 protein
GCU45_RS21235	COG2113	Glycine betaine
GCU45_RS21245	COG4175	Glycine betaine
GCU45_RS21245	COG0517	IMP dehydrogenase activity
GCU45_RS21250	COG1510	regulation of RNA biosynthetic process
GCU45_RS21255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS21265	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GCU45_RS21270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCU45_RS21275	COG0864	Transcriptional regulator
GCU45_RS21280	COG2337	Toxic component of a toxin-antitoxin (TA) module
GCU45_RS21290	COG2183	response to ionizing radiation
GCU45_RS21365	COG0154	amidase activity
GCU45_RS21375	COG2814	Major facilitator Superfamily
GCU45_RS21380	COG1846	Transcriptional regulator
GCU45_RS21405	COG0386	Belongs to the glutathione peroxidase family
GCU45_RS21420	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GCU45_RS21440	COG1764	response to oxidative stress
GCU45_RS21455	COG3011	Protein conserved in bacteria
GCU45_RS21510	COG1090	epimerase
GCU45_RS21520	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GCU45_RS21525	COG0788	formyltetrahydrofolate deformylase activity
GCU45_RS21535	COG1131	(ABC) transporter
GCU45_RS21550	COG0714	Associated with various cellular activities
GCU45_RS21570	COG2205	protein histidine kinase activity
GCU45_RS21585	COG0745	RESPONSE REGULATOR receiver
GCU45_RS21605	COG0166	Belongs to the GPI family
GCU45_RS21610	COG1739	Uncharacterized protein family UPF0029
GCU45_RS21620	COG0432	Pfam Uncharacterised protein family UPF0047
GCU45_RS21655	COG4208	sulfate ABC transporter
GCU45_RS21660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GCU45_RS21665	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GCU45_RS21670	COG2814	Major facilitator Superfamily
GCU45_RS21675	COG0321	lipoyl(octanoyl) transferase activity
GCU45_RS21675	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GCU45_RS21685	COG1486	melibiose metabolic process
GCU45_RS21690	COG0561	phosphatase activity
GCU45_RS21705	COG0456	acetyltransferase
GCU45_RS21710	COG0095	Lipoate-protein ligase
GCU45_RS21715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GCU45_RS21725	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GCU45_RS21730	COG0588	phosphoglycerate mutase activity
GCU45_RS21735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCU45_RS21740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU45_RS21745	COG1120	ATPase activity
GCU45_RS21750	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GCU45_RS21760	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GCU45_RS21765	COG1492	cobalamin metabolic process
GCU45_RS21780	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GCU45_RS21785	COG0006	proline dipeptidase activity
GCU45_RS21790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCU45_RS21800	COG1247	-acetyltransferase
GCU45_RS21805	COG1733	regulation of RNA biosynthetic process
GCU45_RS21835	COG2508	Transcriptional regulator
GCU45_RS21840	COG1953	Uracil, thiamine, allantoin
GCU45_RS21885	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GCU45_RS21995	COG2318	DinB family
GCU45_RS22005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU45_RS22025	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GCU45_RS22035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GCU45_RS22060	COG0561	phosphatase activity
GCU45_RS22080	COG1011	Hydrolase
GCU45_RS22085	COG2318	DinB family
GCU45_RS22125	COG0346	lactoylglutathione lyase activity
GCU45_RS22160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCU45_RS22205	COG1942	4-Oxalocrotonate Tautomerase
GCU45_RS22210	COG3541	Predicted nucleotidyltransferase
GCU45_RS22220	COG1609	Transcriptional regulator
GCU45_RS22225	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GCU45_RS22230	COG2942	2-epimerase
GCU45_RS22250	COG0412	Dienelactone hydrolase
GCU45_RS22280	COG4989	oxidoreductase activity
GCU45_RS22285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCU45_RS22290	COG1733	regulation of RNA biosynthetic process
GCU45_RS22310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GCU45_RS22320	COG1309	transcriptional regulator
GCU45_RS22325	COG2814	Major facilitator Superfamily
GCU45_RS22350	COG2807	transmembrane transport
GCU45_RS22355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS22360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GCU45_RS22395	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GCU45_RS22400	COG1363	Peptidase, m42
GCU45_RS22420	COG0456	acetyltransferase
GCU45_RS22420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GCU45_RS22430	COG2318	DinB family
GCU45_RS22475	COG3340	Belongs to the peptidase S51 family
GCU45_RS22490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GCU45_RS22510	COG4191	Histidine kinase
GCU45_RS22530	COG1120	ATPase activity
GCU45_RS22560	COG0537	adenosine 5'-monophosphoramidase activity
GCU45_RS22590	COG1011	Hydrolase
GCU45_RS22605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GCU45_RS22615	COG1801	Protein of unknown function DUF72
GCU45_RS22620	COG0567	Dehydrogenase, E1 component
GCU45_RS22625	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCU45_RS22635	COG1051	belongs to the nudix hydrolase family
GCU45_RS22665	COG0514	ATP-dependent DNA helicase (RecQ)
GCU45_RS22670	COG1032	radical SAM domain protein
GCU45_RS22680	COG1482	cell wall glycoprotein biosynthetic process
GCU45_RS22685	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GCU45_RS22690	COG1242	4 iron, 4 sulfur cluster binding
GCU45_RS22700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GCU45_RS22705	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GCU45_RS22710	COG0671	phosphoesterase, PA-phosphatase related
GCU45_RS22715	COG1215	transferase activity, transferring glycosyl groups
GCU45_RS22725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GCU45_RS22730	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GCU45_RS22735	COG1744	ABC transporter substrate-binding protein PnrA-like
GCU45_RS22740	COG3845	ABC transporter
GCU45_RS22745	COG4603	Belongs to the binding-protein-dependent transport system permease family
GCU45_RS22750	COG1079	Belongs to the binding-protein-dependent transport system permease family
GCU45_RS22765	COG0028	Belongs to the TPP enzyme family
GCU45_RS22770	COG0440	acetolactate synthase activity
GCU45_RS22775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GCU45_RS22780	COG0667	Aldo Keto reductase
GCU45_RS22785	COG0473	3-isopropylmalate dehydrogenase activity
GCU45_RS22790	COG0450	alkyl hydroperoxide reductase
GCU45_RS22800	COG4191	Histidine kinase
GCU45_RS22805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GCU45_RS22820	COG0393	Putative heavy-metal-binding
GCU45_RS22850	COG2115	Belongs to the xylose isomerase family
GCU45_RS22855	COG1070	Carbohydrate kinase
GCU45_RS22870	COG2197	response regulator
GCU45_RS22875	COG4585	Histidine kinase
GCU45_RS22885	COG0488	(ABC) transporter
GCU45_RS22890	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GCU45_RS22920	COG1193	negative regulation of DNA recombination
GCU45_RS22925	COG3766	membrane
GCU45_RS22935	COG0477	Major facilitator Superfamily
GCU45_RS22955	COG1522	sequence-specific DNA binding
GCU45_RS22960	COG0436	Aminotransferase
GCU45_RS22975	COG2096	Adenosyltransferase
GCU45_RS22980	COG0564	pseudouridine synthase activity
GCU45_RS22985	COG1393	Belongs to the ArsC family
GCU45_RS22995	COG0673	inositol 2-dehydrogenase activity
GCU45_RS23000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCU45_RS23005	COG1940	carbohydrate kinase activity
GCU45_RS23025	COG0598	Magnesium transport protein CorA
GCU45_RS23030	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GCU45_RS23035	COG0626	cystathionine gamma-synthase activity
GCU45_RS23040	COG0626	cystathionine gamma-synthase activity
GCU45_RS23045	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GCU45_RS23055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GCU45_RS23060	COG3584	3D domain protein
GCU45_RS23065	COG4758	membrane
GCU45_RS23070	COG4585	Histidine kinase
GCU45_RS23075	COG2197	response regulator
GCU45_RS23080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCU45_RS23085	COG0745	RESPONSE REGULATOR receiver
GCU45_RS23090	COG5002	protein histidine kinase activity
GCU45_RS23095	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GCU45_RS23100	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GCU45_RS23115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GCU45_RS23120	COG2002	toxin-antitoxin pair type II binding
GCU45_RS23125	COG4632	Exopolysaccharide biosynthesis protein
GCU45_RS23125	COG5434	Belongs to the glycosyl hydrolase 28 family
GCU45_RS23135	COG2197	response regulator
GCU45_RS23140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS23150	COG2766	serine protein kinase
GCU45_RS23155	COG0840	transmembrane signaling receptor activity
GCU45_RS23165	COG0745	RESPONSE REGULATOR receiver
GCU45_RS23170	COG3850	Histidine kinase
GCU45_RS23170	COG5002	protein histidine kinase activity
GCU45_RS23200	COG2719	SpoVR family
GCU45_RS23205	COG2972	Histidine kinase
GCU45_RS23210	COG4753	response regulator
GCU45_RS23210	COG2207	Transcriptional regulator
GCU45_RS23215	COG4209	transmembrane transport
GCU45_RS23220	COG0395	ABC-type sugar transport system, permease component
GCU45_RS23240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GCU45_RS23250	COG2718	Belongs to the UPF0229 family
GCU45_RS23255	COG0352	thiamine-phosphate diphosphorylase activity
GCU45_RS23265	COG2022	thiamine diphosphate biosynthetic process
GCU45_RS23270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCU45_RS23275	COG2911	Protein conserved in bacteria
GCU45_RS23275	COG1361	Conserved repeat domain
GCU45_RS23275	COG3266	domain, Protein
GCU45_RS23285	COG0395	ABC-type sugar transport system, permease component
GCU45_RS23290	COG1175	transmembrane transport
GCU45_RS23295	COG1653	transport
GCU45_RS23305	COG2972	Histidine kinase
GCU45_RS23315	COG2972	Histidine kinase
GCU45_RS23320	COG2207	Transcriptional regulator
GCU45_RS23320	COG4753	response regulator
GCU45_RS23330	COG4209	transmembrane transport
GCU45_RS23335	COG0395	ABC-type sugar transport system, permease component
GCU45_RS23345	COG5520	Belongs to the glycosyl hydrolase 30 family
GCU45_RS23350	COG1846	Transcriptional regulator
GCU45_RS23355	COG0396	ATPase activity
GCU45_RS23360	COG0719	Fe-S assembly protein
GCU45_RS23365	COG0719	Fe-S assembly protein
GCU45_RS23380	COG2814	Major facilitator Superfamily
GCU45_RS23395	COG4166	transmembrane transport
GCU45_RS23400	COG0601	transmembrane transport
GCU45_RS23405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU45_RS23410	COG0444	Belongs to the ABC transporter superfamily
GCU45_RS23415	COG4608	Belongs to the ABC transporter superfamily
GCU45_RS23420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GCU45_RS23425	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GCU45_RS23430	COG3142	Participates in the control of copper homeostasis
GCU45_RS23440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GCU45_RS23445	COG1349	DNA-binding transcription factor activity
GCU45_RS23450	COG1940	carbohydrate kinase activity
GCU45_RS23490	COG5434	Belongs to the glycosyl hydrolase 28 family
GCU45_RS23490	COG4632	Exopolysaccharide biosynthesis protein
GCU45_RS23495	COG1307	EDD domain protein, DegV family
GCU45_RS23505	COG2363	Small membrane protein
GCU45_RS23515	COG3377	Domain of unknown function (DUF1805)
GCU45_RS23525	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GCU45_RS23530	COG0783	Belongs to the Dps family
GCU45_RS23535	COG0396	ATPase activity
GCU45_RS23540	COG0719	Fe-S assembly protein
GCU45_RS23545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GCU45_RS23550	COG0822	iron-sulfur transferase activity
GCU45_RS23555	COG0719	Fe-S assembly protein
GCU45_RS23565	COG0314	molybdopterin synthase activity
GCU45_RS23570	COG0737	Belongs to the 5'-nucleotidase family
GCU45_RS23585	COG0535	radical SAM domain protein
GCU45_RS23590	COG1253	flavin adenine dinucleotide binding
GCU45_RS23610	COG3546	catalase activity
GCU45_RS23630	COG0189	ligase activity
GCU45_RS23635	COG0189	ligase activity
GCU45_RS23640	COG0189	ligase activity
GCU45_RS23645	COG0189	ligase activity
GCU45_RS23650	COG3679	Belongs to the UPF0342 family
GCU45_RS23660	COG4109	DRTGG domain
GCU45_RS23685	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GCU45_RS23695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GCU45_RS23700	COG0825	malonyl-CoA metabolic process
GCU45_RS23705	COG0469	pyruvate kinase activity
GCU45_RS23715	COG3030	protein affecting phage T7 exclusion by the F plasmid
GCU45_RS23720	COG0372	Belongs to the citrate synthase family
GCU45_RS23725	COG0538	isocitrate dehydrogenase activity
GCU45_RS23730	COG0039	L-malate dehydrogenase activity
GCU45_RS23740	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS23750	COG5002	protein histidine kinase activity
GCU45_RS23755	COG0745	RESPONSE REGULATOR receiver
GCU45_RS23765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GCU45_RS23770	COG0704	Plays a role in the regulation of phosphate uptake
GCU45_RS23775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCU45_RS23775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCU45_RS23780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GCU45_RS23785	COG1971	Probably functions as a manganese efflux pump
GCU45_RS23790	COG0237	dephospho-CoA kinase activity
GCU45_RS23805	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GCU45_RS23830	COG2153	protein acetylation
GCU45_RS23845	COG1846	Transcriptional regulator
GCU45_RS23855	COG1309	transcriptional regulator
GCU45_RS23860	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS23865	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS23875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GCU45_RS23880	COG2124	cytochrome p450
GCU45_RS23885	COG1309	transcriptional regulator
GCU45_RS23895	COG0667	Aldo Keto reductase
GCU45_RS23900	COG1279	arginine transmembrane transporter activity
GCU45_RS23905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS23910	COG0596	Alpha beta hydrolase
GCU45_RS23915	COG2208	phosphoserine phosphatase activity
GCU45_RS23920	COG1657	PFAM Prenyltransferase squalene oxidase
GCU45_RS23925	COG0657	acetylesterase activity
GCU45_RS23935	COG2814	Major facilitator Superfamily
GCU45_RS23960	COG1595	DNA-templated transcription, initiation
GCU45_RS23965	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GCU45_RS23990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GCU45_RS24005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GCU45_RS24025	COG0583	DNA-binding transcription factor activity
GCU45_RS24040	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GCU45_RS24040	COG1605	Chorismate mutase
GCU45_RS24045	COG0583	DNA-binding transcription factor activity
GCU45_RS24050	COG0673	inositol 2-dehydrogenase activity
GCU45_RS24055	COG0789	Transcriptional regulator
GCU45_RS24060	COG1902	pentaerythritol trinitrate reductase activity
GCU45_RS24075	COG1349	DNA-binding transcription factor activity
GCU45_RS24110	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GCU45_RS24120	COG4821	SIS domain
GCU45_RS24135	COG3361	conserved protein (COG2071)
GCU45_RS24160	COG0367	asparagine synthase
GCU45_RS24170	COG3944	biosynthesis protein
GCU45_RS24175	COG0489	protein tyrosine kinase activity
GCU45_RS24180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCU45_RS24185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GCU45_RS24205	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS24220	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GCU45_RS24245	COG1132	(ABC) transporter
GCU45_RS24250	COG2084	Dehydrogenase
GCU45_RS24260	COG1960	acyl-CoA dehydrogenase activity
GCU45_RS24265	COG1910	domain protein
GCU45_RS24270	COG0725	ABC transporter, periplasmic molybdate-binding protein
GCU45_RS24275	COG4149	molybdate abc transporter
GCU45_RS24285	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GCU45_RS24290	COG3842	ATPase activity
GCU45_RS24295	COG0395	ABC-type sugar transport system, permease component
GCU45_RS24300	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCU45_RS24310	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GCU45_RS24330	COG0778	Nitroreductase
GCU45_RS24335	COG0583	DNA-binding transcription factor activity
GCU45_RS24340	COG0402	S-adenosylhomocysteine deaminase activity
GCU45_RS24345	COG0402	S-adenosylhomocysteine deaminase activity
GCU45_RS24355	COG0667	Aldo Keto reductase
GCU45_RS24360	COG1595	DNA-templated transcription, initiation
GCU45_RS24375	COG2814	Major facilitator Superfamily
GCU45_RS24380	COG2755	lipolytic protein G-D-S-L family
GCU45_RS24385	COG1904	glucuronate isomerase
GCU45_RS24390	COG2721	sulfolactate sulfo-lyase activity
GCU45_RS24395	COG0246	Mannitol dehydrogenase
GCU45_RS24400	COG1609	Transcriptional regulator
GCU45_RS24405	COG2207	Transcriptional regulator
GCU45_RS24410	COG0395	ABC-type sugar transport system, permease component
GCU45_RS24415	COG4209	transmembrane transport
GCU45_RS24420	COG1653	transport
GCU45_RS24425	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GCU45_RS24435	COG1073	alpha beta
GCU45_RS24445	COG3507	Belongs to the glycosyl hydrolase 43 family
GCU45_RS24460	COG0697	spore germination
GCU45_RS24470	COG2318	DinB family
GCU45_RS24475	COG1309	transcriptional regulator
GCU45_RS24480	COG3321	synthase
GCU45_RS24480	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS24480	COG0604	alcohol dehydrogenase
GCU45_RS24485	COG0477	Major facilitator Superfamily
GCU45_RS24495	COG2205	protein histidine kinase activity
GCU45_RS24500	COG0745	RESPONSE REGULATOR receiver
GCU45_RS24515	COG0583	DNA-binding transcription factor activity
GCU45_RS24540	COG0673	inositol 2-dehydrogenase activity
GCU45_RS24550	COG0534	Mate efflux family protein
GCU45_RS24560	COG2267	carboxylic ester hydrolase activity
GCU45_RS24570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCU45_RS24580	COG0583	DNA-binding transcription factor activity
GCU45_RS24585	COG2807	transmembrane transport
GCU45_RS24600	COG2226	methyltransferase
GCU45_RS24610	COG4122	O-methyltransferase activity
GCU45_RS24630	COG0789	Transcriptional regulator
GCU45_RS24655	COG0789	Transcriptional regulator
GCU45_RS24665	COG1131	(ABC) transporter
GCU45_RS24680	COG1653	transport
GCU45_RS24685	COG1175	transmembrane transport
GCU45_RS24690	COG0395	ABC-type sugar transport system, permease component
GCU45_RS24705	COG2207	Transcriptional regulator
GCU45_RS24710	COG2814	Major facilitator Superfamily
GCU45_RS24730	COG1368	sulfuric ester hydrolase activity
GCU45_RS24735	COG0803	Belongs to the bacterial solute-binding protein 9 family
GCU45_RS24740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCU45_RS24745	COG1121	(ABC) transporter
GCU45_RS24755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GCU45_RS24760	COG0573	inorganic phosphate transmembrane transporter activity
GCU45_RS24765	COG0581	inorganic phosphate transmembrane transporter activity
GCU45_RS24775	COG0589	response to stress
GCU45_RS24780	COG2814	Major facilitator Superfamily
GCU45_RS24785	COG0789	Transcriptional regulator
GCU45_RS24790	COG0542	response to heat
GCU45_RS24800	COG0726	polysaccharide deacetylase
GCU45_RS24815	COG2445	Protein of unknown function DUF86
GCU45_RS24825	COG4980	gas vesicle protein
GCU45_RS24830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GCU45_RS24855	COG0656	L-ascorbic acid biosynthetic process
GCU45_RS24860	COG1368	sulfuric ester hydrolase activity
GCU45_RS24865	COG0116	Belongs to the methyltransferase superfamily
GCU45_RS24870	COG4122	O-methyltransferase activity
GCU45_RS24875	COG0252	asparaginase activity
GCU45_RS24880	COG2814	Major facilitator Superfamily
GCU45_RS24885	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GCU45_RS24890	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GCU45_RS24895	COG2843	Capsule synthesis protein
GCU45_RS24900	COG0584	glycerophosphoryl diester phosphodiesterase
GCU45_RS24915	COG0488	(ABC) transporter
GCU45_RS24930	COG1363	Peptidase, m42
GCU45_RS24935	COG5416	Lipopolysaccharide assembly protein A domain
GCU45_RS24940	COG1164	Oligoendopeptidase f
GCU45_RS24975	COG0534	Mate efflux family protein
GCU45_RS24990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GCU45_RS24995	COG0513	Belongs to the DEAD box helicase family
GCU45_RS25005	COG5578	integral membrane protein
GCU45_RS25020	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GCU45_RS25025	COG0705	Rhomboid family
GCU45_RS25030	COG0583	DNA-binding transcription factor activity
GCU45_RS25035	COG2738	Putative neutral zinc metallopeptidase
GCU45_RS25040	COG0789	Transcriptional regulator
GCU45_RS25045	COG0004	ammonium transporteR
GCU45_RS25065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCU45_RS25070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GCU45_RS25075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GCU45_RS25080	COG1141	Ferredoxin
GCU45_RS25085	COG1376	ErfK ybiS ycfS ynhG family protein
GCU45_RS25090	COG0167	dihydroorotate dehydrogenase activity
GCU45_RS25095	COG2357	RelA SpoT domain protein
GCU45_RS25100	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GCU45_RS25100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GCU45_RS25105	COG1187	pseudouridine synthase activity
GCU45_RS25110	COG0561	phosphatase activity
GCU45_RS25115	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GCU45_RS25115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GCU45_RS25120	COG5002	protein histidine kinase activity
GCU45_RS25120	COG3447	MASE1 domain protein
GCU45_RS25120	COG5001	Diguanylate cyclase
GCU45_RS25130	COG3949	Membrane
GCU45_RS25135	COG0586	Pfam SNARE associated Golgi protein
GCU45_RS25140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GCU45_RS25165	COG0582	viral genome integration into host DNA
GCU45_RS25190	COG2814	Major facilitator Superfamily
GCU45_RS25195	COG0640	Transcriptional regulator
GCU45_RS25210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS25245	COG1309	transcriptional regulator
GCU45_RS25250	COG2814	Major facilitator Superfamily
GCU45_RS25255	COG0596	Alpha beta hydrolase
GCU45_RS25265	COG0789	Transcriptional regulator
GCU45_RS25265	COG4978	Transcriptional regulator
GCU45_RS25270	COG2814	Major facilitator Superfamily
GCU45_RS25280	COG2197	response regulator
GCU45_RS25290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GCU45_RS25310	COG0456	acetyltransferase
GCU45_RS25320	COG2814	Major facilitator Superfamily
GCU45_RS25325	COG0640	Transcriptional regulator
GCU45_RS25330	COG0477	Major facilitator Superfamily
GCU45_RS25335	COG2814	Major facilitator Superfamily
GCU45_RS25345	COG2861	carbohydrate metabolic process
GCU45_RS25370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GCU45_RS25395	COG0583	DNA-binding transcription factor activity
GCU45_RS25400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS25405	COG0747	negative chemotaxis
GCU45_RS25420	COG4172	Belongs to the ABC transporter superfamily
GCU45_RS25425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS25430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS25440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GCU45_RS25460	COG1349	DNA-binding transcription factor activity
GCU45_RS25470	COG4209	transmembrane transport
GCU45_RS25475	COG0395	ABC-type sugar transport system, permease component
GCU45_RS25510	COG0673	inositol 2-dehydrogenase activity
GCU45_RS25525	COG1349	DNA-binding transcription factor activity
GCU45_RS25530	COG1940	carbohydrate kinase activity
GCU45_RS25535	COG1940	carbohydrate kinase activity
GCU45_RS25540	COG0363	glucosamine-6-phosphate deaminase activity
GCU45_RS25545	COG1653	transport
GCU45_RS25555	COG0395	ABC-type sugar transport system, permease component
GCU45_RS25570	COG0483	inositol monophosphate 1-phosphatase activity
GCU45_RS25575	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GCU45_RS25590	COG1595	DNA-templated transcription, initiation
GCU45_RS25635	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GCU45_RS25640	COG0395	ABC-type sugar transport system, permease component
GCU45_RS25645	COG1175	transmembrane transport
GCU45_RS25655	COG4977	sequence-specific DNA binding
GCU45_RS25655	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS25670	COG0395	ABC-type sugar transport system, permease component
GCU45_RS25695	COG4209	transmembrane transport
GCU45_RS25700	COG0395	ABC-type sugar transport system, permease component
GCU45_RS25705	COG2207	Transcriptional regulator
GCU45_RS25705	COG4753	response regulator
GCU45_RS25710	COG2972	Histidine kinase
GCU45_RS25715	COG4753	response regulator
GCU45_RS25715	COG2207	Transcriptional regulator
GCU45_RS25725	COG3507	Belongs to the glycosyl hydrolase 43 family
GCU45_RS25725	COG2382	esterase
GCU45_RS25725	COG3693	PFAM glycoside hydrolase, family 10
GCU45_RS25745	COG1653	transport
GCU45_RS25750	COG2972	Histidine kinase
GCU45_RS25760	COG3507	Belongs to the glycosyl hydrolase 43 family
GCU45_RS25765	COG0577	efflux transmembrane transporter activity
GCU45_RS25765	COG1136	(ABC) transporter
GCU45_RS25770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCU45_RS25780	COG1136	(ABC) transporter
GCU45_RS25780	COG0577	efflux transmembrane transporter activity
GCU45_RS25790	COG2207	Transcriptional regulator
GCU45_RS25805	COG1175	transmembrane transport
GCU45_RS25810	COG0395	ABC-type sugar transport system, permease component
GCU45_RS25830	COG1175	transmembrane transport
GCU45_RS25835	COG0395	ABC-type sugar transport system, permease component
GCU45_RS25860	COG2207	Transcriptional regulator
GCU45_RS25885	COG1309	transcriptional regulator
GCU45_RS25895	COG0584	glycerophosphoryl diester phosphodiesterase
GCU45_RS25900	COG5566	PFAM Mor transcription activator
GCU45_RS25920	COG1349	DNA-binding transcription factor activity
GCU45_RS25940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GCU45_RS25950	COG0738	Major facilitator superfamily
GCU45_RS25955	COG0110	maltose O-acetyltransferase activity
GCU45_RS25965	COG2207	Transcriptional regulator
GCU45_RS25975	COG0477	Major facilitator Superfamily
GCU45_RS26005	COG1595	DNA-templated transcription, initiation
GCU45_RS26010	COG0366	Alpha amylase catalytic
GCU45_RS26020	COG0300	oxidoreductase activity
GCU45_RS26025	COG2207	Transcriptional regulator
GCU45_RS26025	COG4753	response regulator
GCU45_RS26030	COG2972	Histidine kinase
GCU45_RS26040	COG1175	transmembrane transport
GCU45_RS26065	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS26065	COG4977	sequence-specific DNA binding
GCU45_RS26075	COG3408	Glycogen debranching enzyme
GCU45_RS26080	COG2814	Major facilitator Superfamily
GCU45_RS26090	COG0583	DNA-binding transcription factor activity
GCU45_RS26100	COG0656	L-ascorbic acid biosynthetic process
GCU45_RS26105	COG4221	oxidoreductase activity
GCU45_RS26115	COG2207	Transcriptional regulator
GCU45_RS26130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCU45_RS26140	COG0667	Aldo Keto reductase
GCU45_RS26145	COG0667	Aldo Keto reductase
GCU45_RS26190	COG2972	Histidine kinase
GCU45_RS26195	COG4753	response regulator
GCU45_RS26195	COG2207	Transcriptional regulator
GCU45_RS26200	COG2182	Extracellular solute-binding protein
GCU45_RS26205	COG1175	transmembrane transport
GCU45_RS26210	COG0395	ABC-type sugar transport system, permease component
GCU45_RS26215	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GCU45_RS26230	COG0561	phosphatase activity
GCU45_RS26235	COG2801	Transposase and inactivated derivatives
GCU45_RS26255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCU45_RS26275	COG0640	Transcriptional regulator
GCU45_RS26280	COG2814	Major facilitator Superfamily
GCU45_RS26310	COG1388	LysM domain
GCU45_RS26315	COG0791	NLP P60 protein
GCU45_RS26320	COG2132	Multicopper oxidase
GCU45_RS26330	COG0745	RESPONSE REGULATOR receiver
GCU45_RS26335	COG5002	protein histidine kinase activity
GCU45_RS26350	COG2217	Heavy metal translocating P-type atpase
GCU45_RS26365	COG0028	Belongs to the TPP enzyme family
GCU45_RS26375	COG0028	Belongs to the TPP enzyme family
GCU45_RS26380	COG3300	MHYT domain
GCU45_RS26380	COG5001	Diguanylate cyclase
GCU45_RS26385	COG0628	permease
GCU45_RS26395	COG0640	Transcriptional regulator
GCU45_RS26420	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GCU45_RS26425	COG2602	Beta-lactamase
GCU45_RS26430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS26465	COG1609	Transcriptional regulator
GCU45_RS26470	COG0693	protein deglycase activity
GCU45_RS26475	COG0596	Alpha beta hydrolase
GCU45_RS26485	COG2378	regulation of single-species biofilm formation
GCU45_RS26490	COG2318	DinB family
GCU45_RS26500	COG1175	transmembrane transport
GCU45_RS26505	COG0395	ABC-type sugar transport system, permease component
GCU45_RS26510	COG1846	Transcriptional regulator
GCU45_RS26515	COG2072	flavoprotein involved in K transport
GCU45_RS26530	COG1595	DNA-templated transcription, initiation
GCU45_RS26535	COG0778	Nitroreductase
GCU45_RS26540	COG2226	methyltransferase
GCU45_RS26545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCU45_RS26555	COG2323	membrane
GCU45_RS26565	COG1294	oxidase, subunit
GCU45_RS26570	COG1271	oxidase subunit
GCU45_RS26575	COG0789	Transcriptional regulator
GCU45_RS26580	COG2084	Dehydrogenase
GCU45_RS26585	COG3250	beta-galactosidase activity
GCU45_RS26615	COG1846	Transcriptional regulator
GCU45_RS26620	COG0346	lactoylglutathione lyase activity
GCU45_RS26625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCU45_RS26635	COG2378	regulation of single-species biofilm formation
GCU45_RS26640	COG0604	alcohol dehydrogenase
GCU45_RS26645	COG0583	DNA-binding transcription factor activity
GCU45_RS26675	COG4209	transmembrane transport
GCU45_RS26680	COG0395	ABC-type sugar transport system, permease component
GCU45_RS26685	COG1653	transport
GCU45_RS26700	COG1595	DNA-templated transcription, initiation
GCU45_RS26705	COG0753	catalase activity
GCU45_RS26710	COG0385	Bile acid
GCU45_RS26720	COG2211	Major facilitator Superfamily
GCU45_RS26730	COG0673	inositol 2-dehydrogenase activity
GCU45_RS26735	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS26760	COG2207	Transcriptional regulator
GCU45_RS26765	COG4209	transmembrane transport
GCU45_RS26770	COG0395	ABC-type sugar transport system, permease component
GCU45_RS26775	COG1653	transport
GCU45_RS26785	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS26785	COG2207	Transcriptional regulator
GCU45_RS26790	COG1175	transmembrane transport
GCU45_RS26795	COG2182	Extracellular solute-binding protein
GCU45_RS26800	COG0395	ABC-type sugar transport system, permease component
GCU45_RS26805	COG1486	melibiose metabolic process
GCU45_RS26825	COG2972	Histidine kinase
GCU45_RS26830	COG2207	Transcriptional regulator
GCU45_RS26830	COG4753	response regulator
GCU45_RS26835	COG4213	ABC transporter substrate-binding protein
GCU45_RS26845	COG4214	carbohydrate transport
GCU45_RS26865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCU45_RS26890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GCU45_RS26895	COG1454	alcohol dehydrogenase
GCU45_RS26895	COG1012	belongs to the aldehyde dehydrogenase family
GCU45_RS26900	COG0746	molybdenum cofactor guanylyltransferase activity
GCU45_RS26910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GCU45_RS26915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCU45_RS26925	COG2197	response regulator
GCU45_RS26930	COG4585	Histidine kinase
GCU45_RS26935	COG0105	UTP biosynthetic process
GCU45_RS26950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS26970	COG1131	(ABC) transporter
GCU45_RS26985	COG0745	RESPONSE REGULATOR receiver
GCU45_RS27005	COG2362	D-Aminopeptidase
GCU45_RS27010	COG0601	transmembrane transport
GCU45_RS27015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCU45_RS27020	COG0444	Belongs to the ABC transporter superfamily
GCU45_RS27025	COG4166	transmembrane transport
GCU45_RS27030	COG1619	proteins homologs of microcin C7 resistance protein MccF
GCU45_RS27035	COG4948	Mandelate Racemase Muconate Lactonizing
GCU45_RS27065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GCU45_RS27080	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GCU45_RS27095	COG2207	Transcriptional regulator
GCU45_RS27100	COG3534	alpha-L-arabinofuranosidase
GCU45_RS27105	COG1609	Transcriptional regulator
GCU45_RS27115	COG1175	transmembrane transport
GCU45_RS27120	COG0395	ABC-type sugar transport system, permease component
GCU45_RS27135	COG0733	neurotransmitter:sodium symporter activity
GCU45_RS27145	COG2059	Chromate
GCU45_RS27155	COG1361	Conserved repeat domain
GCU45_RS27160	COG1309	transcriptional regulator
GCU45_RS27165	COG2814	Major facilitator Superfamily
GCU45_RS27175	COG1609	Transcriptional regulator
GCU45_RS27180	COG4209	transmembrane transport
GCU45_RS27185	COG0395	ABC-type sugar transport system, permease component
GCU45_RS27195	COG1621	beta-fructofuranosidase activity
GCU45_RS27200	COG1940	carbohydrate kinase activity
GCU45_RS27210	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS27215	COG1846	Transcriptional regulator
GCU45_RS27240	COG1595	DNA-templated transcription, initiation
GCU45_RS27250	COG4533	DNA binding
GCU45_RS27255	COG0454	-acetyltransferase
GCU45_RS27260	COG5002	protein histidine kinase activity
GCU45_RS27290	COG0346	lactoylglutathione lyase activity
GCU45_RS27335	COG4941	Belongs to the sigma-70 factor family
GCU45_RS27350	COG1368	sulfuric ester hydrolase activity
GCU45_RS27370	COG1428	Deoxynucleoside kinase
GCU45_RS27375	COG1428	Deoxynucleoside kinase
GCU45_RS27385	COG3964	amidohydrolase
GCU45_RS27415	COG4209	transmembrane transport
GCU45_RS27420	COG0395	ABC-type sugar transport system, permease component
GCU45_RS27425	COG1653	transport
GCU45_RS27435	COG0156	8-amino-7-oxononanoate synthase activity
GCU45_RS27440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCU45_RS27455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GCU45_RS27460	COG1988	membrane-bound metal-dependent
GCU45_RS27465	COG1396	sequence-specific DNA binding
GCU45_RS27475	COG3944	biosynthesis protein
GCU45_RS27480	COG0489	protein tyrosine kinase activity
GCU45_RS27485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCU45_RS27490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GCU45_RS27555	COG1131	(ABC) transporter
GCU45_RS27575	COG1012	belongs to the aldehyde dehydrogenase family
GCU45_RS27580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCU45_RS27585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GCU45_RS27595	COG2323	membrane
GCU45_RS27605	COG0671	phosphoesterase, PA-phosphatase related
GCU45_RS27610	COG0628	permease
GCU45_RS27620	COG4129	membrane
GCU45_RS27630	COG0745	RESPONSE REGULATOR receiver
GCU45_RS27640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GCU45_RS27645	COG3973	AAA domain
GCU45_RS27650	COG2207	Transcriptional regulator
GCU45_RS27650	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS27655	COG1501	Belongs to the glycosyl hydrolase 31 family
GCU45_RS27660	COG2814	Major facilitator Superfamily
GCU45_RS27665	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS27665	COG3347	Dehydrogenase
GCU45_RS27670	COG0247	lactate metabolic process
GCU45_RS27675	COG1139	Iron-sulfur cluster binding protein
GCU45_RS27680	COG1556	Lactate utilization protein
GCU45_RS27685	COG1349	DNA-binding transcription factor activity
GCU45_RS27690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GCU45_RS27695	COG0517	IMP dehydrogenase activity
GCU45_RS27700	COG1368	sulfuric ester hydrolase activity
GCU45_RS27710	COG1131	(ABC) transporter
GCU45_RS27755	COG0546	phosphoglycolate phosphatase activity
GCU45_RS27770	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GCU45_RS27780	COG1846	Transcriptional regulator
GCU45_RS27785	COG4895	conserved protein (DUF2196)
GCU45_RS27800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCU45_RS27810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GCU45_RS27855	COG0366	Alpha amylase catalytic
GCU45_RS27900	COG0742	ribosomal rna small subunit methyltransferase
GCU45_RS27905	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GCU45_RS27910	COG3314	Sporulation integral membrane protein YlbJ
GCU45_RS27915	COG3480	Lon protease (S16) C-terminal proteolytic domain
GCU45_RS27920	COG1323	Belongs to the UPF0348 family
GCU45_RS27930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GCU45_RS27935	COG1349	DNA-binding transcription factor activity
GCU45_RS27940	COG0416	fatty acid biosynthetic process
GCU45_RS27950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GCU45_RS27955	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS27960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCU45_RS27965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCU45_RS27970	COG0571	ribonuclease III activity
GCU45_RS27975	COG1196	nuclear chromosome segregation
GCU45_RS27980	COG0552	protein localization to endoplasmic reticulum
GCU45_RS28000	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS28005	COG1272	protein, Hemolysin III
GCU45_RS28010	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GCU45_RS28015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GCU45_RS28020	COG0228	four-way junction DNA binding
GCU45_RS28030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GCU45_RS28035	COG0336	Belongs to the RNA methyltransferase TrmD family
GCU45_RS28060	COG2211	Major facilitator Superfamily
GCU45_RS28080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GCU45_RS28085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCU45_RS28090	COG0765	amino acid transport
GCU45_RS28095	COG1126	abc transporter atp-binding protein
GCU45_RS28105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GCU45_RS28115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCU45_RS28120	COG0792	nuclease activity
GCU45_RS28130	COG0606	chelatase, subunit chli
GCU45_RS28135	COG1846	Transcriptional regulator
GCU45_RS28140	COG0045	succinate-CoA ligase (ADP-forming) activity
GCU45_RS28145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GCU45_RS28150	COG0758	DNA mediated transformation
GCU45_RS28150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GCU45_RS28155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCU45_RS28160	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GCU45_RS28165	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GCU45_RS28170	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GCU45_RS28175	COG1815	bacterial-type flagellum-dependent cell motility
GCU45_RS28180	COG1558	bacterial-type flagellum-dependent cell motility
GCU45_RS28185	COG1677	Flagellar hook-basal body complex protein FliE
GCU45_RS28190	COG1766	The M ring may be actively involved in energy transduction
GCU45_RS28195	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCU45_RS28205	COG1157	protein secretion by the type III secretion system
GCU45_RS28210	COG2882	bacterial-type flagellum organization
GCU45_RS28225	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GCU45_RS28235	COG4786	Flagellar basal body rod
GCU45_RS28250	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCU45_RS28255	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCU45_RS28255	COG1776	CheC inhibitor of MCP methylation
GCU45_RS28260	COG2201	protein-glutamate methylesterase activity
GCU45_RS28265	COG3190	flagellar
GCU45_RS28270	COG1338	Plays a role in the flagellum-specific transport system
GCU45_RS28275	COG1987	bacterial-type flagellum assembly
GCU45_RS28280	COG1684	flagellar biosynthetic protein fliR
GCU45_RS28285	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCU45_RS28290	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCU45_RS28295	COG1419	protein localization to endoplasmic reticulum
GCU45_RS28300	COG0455	bacterial-type flagellum organization
GCU45_RS28305	COG2201	protein-glutamate methylesterase activity
GCU45_RS28310	COG0643	Histidine kinase
GCU45_RS28310	COG2198	Histidine kinase
GCU45_RS28315	COG0835	chemotaxis
GCU45_RS28320	COG1776	CheC inhibitor of MCP methylation
GCU45_RS28325	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GCU45_RS28335	COG1191	sigma factor activity
GCU45_RS28360	COG0052	Belongs to the universal ribosomal protein uS2 family
GCU45_RS28365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GCU45_RS28370	COG0528	UMP kinase activity
GCU45_RS28375	COG0233	cytoplasmic translational termination
GCU45_RS28380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GCU45_RS28385	COG4589	Belongs to the CDS family
GCU45_RS28390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GCU45_RS28395	COG0750	zinc metalloprotease
GCU45_RS28400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GCU45_RS28405	COG2176	DNA-directed DNA polymerase activity
GCU45_RS28410	COG0779	Required for maturation of 30S ribosomal subunits
GCU45_RS28415	COG0195	Participates in both transcription termination and antitermination
GCU45_RS28425	COG1358	cellular component organization or biogenesis
GCU45_RS28430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GCU45_RS28435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GCU45_RS28440	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GCU45_RS28445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GCU45_RS28450	COG0196	riboflavin kinase activity
GCU45_RS28455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GCU45_RS28460	COG1185	polyribonucleotide nucleotidyltransferase activity
GCU45_RS28465	COG0726	polysaccharide deacetylase
GCU45_RS28470	COG0612	Peptidase, M16
GCU45_RS28475	COG0756	dUTP diphosphatase activity
GCU45_RS28480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCU45_RS28485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GCU45_RS28490	COG0527	aspartate kinase activity
GCU45_RS28500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GCU45_RS28505	COG0740	serine-type endopeptidase activity
GCU45_RS28515	COG1674	ftsk spoiiie
GCU45_RS28515	COG4980	gas vesicle protein
GCU45_RS28525	COG0612	Peptidase, M16
GCU45_RS28530	COG0612	Peptidase, M16
GCU45_RS28535	COG0300	oxidoreductase activity
GCU45_RS28550	COG1426	Protein conserved in bacteria
GCU45_RS28560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GCU45_RS28575	COG2137	regulation of response to DNA damage stimulus
GCU45_RS28585	COG1692	metallophosphoesterase
GCU45_RS28590	COG2359	stage V sporulation protein S
GCU45_RS28600	COG4869	propanediol catabolic process
GCU45_RS28605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GCU45_RS28610	COG4550	Control of competence regulator ComK, YlbF/YmcA
GCU45_RS28625	COG1335	isochorismatase
GCU45_RS28630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GCU45_RS28635	COG0604	alcohol dehydrogenase
GCU45_RS28645	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCU45_RS28650	COG0523	cobalamin synthesis protein
GCU45_RS28660	COG1297	OPT oligopeptide transporter protein
GCU45_RS28670	COG0018	arginyl-trna synthetase
GCU45_RS28695	COG4209	transmembrane transport
GCU45_RS28700	COG0395	ABC-type sugar transport system, permease component
GCU45_RS28715	COG2972	Histidine kinase
GCU45_RS28720	COG1132	(ABC) transporter
GCU45_RS28725	COG1132	(ABC) transporter
GCU45_RS28735	COG1874	Beta-galactosidase
GCU45_RS28740	COG4209	transmembrane transport
GCU45_RS28745	COG0395	ABC-type sugar transport system, permease component
GCU45_RS28750	COG1653	transport
GCU45_RS28755	COG2207	Transcriptional regulator
GCU45_RS28775	COG1132	(ABC) transporter
GCU45_RS28780	COG2707	UPF0756 membrane protein
GCU45_RS28785	COG0492	ferredoxin-NADP+ reductase activity
GCU45_RS28825	COG1674	ftsk spoiiie
GCU45_RS28865	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS28870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCU45_RS28875	COG1643	Atp-dependent helicase
GCU45_RS28895	COG2259	Doxx family
GCU45_RS28920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GCU45_RS28930	COG3599	regulation of cell shape
GCU45_RS28940	COG1714	RDD family
GCU45_RS28945	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GCU45_RS28945	COG2124	cytochrome p450
GCU45_RS28955	COG0456	acetyltransferase
GCU45_RS28965	COG0531	amino acid
GCU45_RS28975	COG0697	spore germination
GCU45_RS28980	COG2340	Cysteine-rich secretory protein family
GCU45_RS28985	COG1660	Displays ATPase and GTPase activities
GCU45_RS28990	COG1011	Hydrolase
GCU45_RS29000	COG0456	acetyltransferase
GCU45_RS29015	COG1051	belongs to the nudix hydrolase family
GCU45_RS29025	COG2329	Antibiotic biosynthesis monooxygenase
GCU45_RS29035	COG1247	-acetyltransferase
GCU45_RS29040	COG2226	methyltransferase
GCU45_RS29045	COG2966	Psort location CytoplasmicMembrane, score
GCU45_RS29060	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCU45_RS29080	COG2318	DinB family
GCU45_RS29090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GCU45_RS29095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCU45_RS29105	COG0346	lactoylglutathione lyase activity
GCU45_RS29110	COG0406	alpha-ribazole phosphatase activity
GCU45_RS29120	COG1105	Belongs to the carbohydrate kinase PfkB family
GCU45_RS29125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCU45_RS29140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GCU45_RS29145	COG2205	protein histidine kinase activity
GCU45_RS29145	COG0784	Response regulator, receiver
GCU45_RS29150	COG1609	Transcriptional regulator
GCU45_RS29155	COG0673	inositol 2-dehydrogenase activity
GCU45_RS29165	COG0673	inositol 2-dehydrogenase activity
GCU45_RS29185	COG1418	mRNA catabolic process
GCU45_RS29195	COG3850	Histidine kinase
GCU45_RS29200	COG2197	response regulator
GCU45_RS29205	COG0697	spore germination
GCU45_RS29225	COG2190	(PTS) system
GCU45_RS29230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCU45_RS29230	COG1263	PTS System
GCU45_RS29240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GCU45_RS29245	COG1609	Transcriptional regulator
GCU45_RS29255	COG1070	Carbohydrate kinase
GCU45_RS29260	COG0235	Class ii aldolase
GCU45_RS29265	COG0442	prolyl-tRNA aminoacylation
GCU45_RS29280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU45_RS29300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCU45_RS29315	COG1121	(ABC) transporter
GCU45_RS29320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCU45_RS29325	COG0803	Belongs to the bacterial solute-binding protein 9 family
GCU45_RS29330	COG0523	cobalamin synthesis protein
GCU45_RS29340	COG1131	(ABC) transporter
GCU45_RS29360	COG2205	protein histidine kinase activity
GCU45_RS29370	COG4533	DNA binding
GCU45_RS29375	COG0840	transmembrane signaling receptor activity
GCU45_RS29395	COG2233	PERMEase
GCU45_RS29400	COG0402	S-adenosylhomocysteine deaminase activity
GCU45_RS29415	COG1764	response to oxidative stress
GCU45_RS29420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS29430	COG0667	Aldo Keto reductase
GCU45_RS29435	COG2755	lipolytic protein G-D-S-L family
GCU45_RS29435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GCU45_RS29450	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GCU45_RS29460	COG1175	transmembrane transport
GCU45_RS29465	COG0395	ABC-type sugar transport system, permease component
GCU45_RS29470	COG2972	Histidine kinase
GCU45_RS29475	COG4753	response regulator
GCU45_RS29475	COG2207	Transcriptional regulator
GCU45_RS29485	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GCU45_RS29490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCU45_RS29510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GCU45_RS29520	COG1846	Transcriptional regulator
GCU45_RS29525	COG2814	Major facilitator Superfamily
GCU45_RS29530	COG2205	protein histidine kinase activity
GCU45_RS29535	COG0745	RESPONSE REGULATOR receiver
GCU45_RS29555	COG1309	transcriptional regulator
GCU45_RS29560	COG0702	epimerase
GCU45_RS29565	COG3631	Ketosteroid isomerase-related protein
GCU45_RS29580	COG1309	transcriptional regulator
GCU45_RS29585	COG1511	domain protein
GCU45_RS29590	COG0024	Methionine aminopeptidase
GCU45_RS29615	COG1027	Aspartate ammonia-lyase
GCU45_RS29625	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GCU45_RS29630	COG2329	Antibiotic biosynthesis monooxygenase
GCU45_RS29640	COG0708	Exodeoxyribonuclease III
GCU45_RS29650	COG2814	Major facilitator Superfamily
GCU45_RS29660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCU45_RS29665	COG1136	(ABC) transporter
GCU45_RS29670	COG0577	efflux transmembrane transporter activity
GCU45_RS29670	COG1136	(ABC) transporter
GCU45_RS29675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GCU45_RS29680	COG1309	transcriptional regulator
GCU45_RS29700	COG1113	amino acid transport
GCU45_RS29740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCU45_RS29770	COG1063	alcohol dehydrogenase
GCU45_RS29790	COG0523	cobalamin synthesis protein
GCU45_RS29795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GCU45_RS29820	COG0464	growth
GCU45_RS29825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GCU45_RS29875	COG0730	response to heat
GCU45_RS29880	COG1472	Belongs to the glycosyl hydrolase 3 family
GCU45_RS29890	COG0697	spore germination
GCU45_RS29900	COG1132	(ABC) transporter
GCU45_RS29905	COG0745	RESPONSE REGULATOR receiver
GCU45_RS29910	COG2205	protein histidine kinase activity
GCU45_RS29915	COG1136	(ABC) transporter
GCU45_RS29920	COG0577	efflux transmembrane transporter activity
GCU45_RS29940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCU45_RS29945	COG0640	Transcriptional regulator
GCU45_RS29950	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GCU45_RS29960	COG1653	transport
GCU45_RS29965	COG4209	transmembrane transport
GCU45_RS29970	COG0395	ABC-type sugar transport system, permease component
GCU45_RS29975	COG2207	Transcriptional regulator
GCU45_RS29980	COG2217	Heavy metal translocating P-type atpase
GCU45_RS29990	COG0640	Transcriptional regulator
GCU45_RS30000	COG0667	Aldo Keto reductase
GCU45_RS30010	COG4977	sequence-specific DNA binding
GCU45_RS30010	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS30025	COG4209	transmembrane transport
GCU45_RS30030	COG0395	ABC-type sugar transport system, permease component
GCU45_RS30050	COG0490	domain, Protein
GCU45_RS30055	COG0475	glutathione-regulated potassium exporter activity
GCU45_RS30060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GCU45_RS30065	COG1609	Transcriptional regulator
GCU45_RS30070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCU45_RS30075	COG1869	D-ribose catabolic process
GCU45_RS30080	COG1129	ABC transporter
GCU45_RS30085	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCU45_RS30090	COG1879	ABC-type sugar transport system periplasmic component
GCU45_RS30095	COG1404	Belongs to the peptidase S8 family
GCU45_RS30110	COG2318	DinB family
GCU45_RS30120	COG3458	cephalosporin-C deacetylase activity
GCU45_RS30125	COG1335	isochorismatase
GCU45_RS30145	COG2378	regulation of single-species biofilm formation
GCU45_RS30150	COG2814	Major facilitator Superfamily
GCU45_RS30155	COG4978	Transcriptional regulator
GCU45_RS30155	COG0789	Transcriptional regulator
GCU45_RS30160	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS30175	COG0701	Predicted permease
GCU45_RS30180	COG2972	Histidine kinase
GCU45_RS30190	COG1653	transport
GCU45_RS30195	COG4209	transmembrane transport
GCU45_RS30200	COG0395	ABC-type sugar transport system, permease component
GCU45_RS30205	COG0673	inositol 2-dehydrogenase activity
GCU45_RS30245	COG1376	ErfK ybiS ycfS ynhG family protein
GCU45_RS30265	COG0477	Major facilitator Superfamily
GCU45_RS30275	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS30300	COG0438	transferase activity, transferring glycosyl groups
GCU45_RS30315	COG1215	transferase activity, transferring glycosyl groups
GCU45_RS30330	COG0720	synthase
GCU45_RS30335	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GCU45_RS30340	COG2207	Transcriptional regulator
GCU45_RS30340	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS30350	COG0673	inositol 2-dehydrogenase activity
GCU45_RS30370	COG0789	Transcriptional regulator
GCU45_RS30380	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GCU45_RS30385	COG1984	allophanate hydrolase subunit 2
GCU45_RS30390	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GCU45_RS30395	COG1309	transcriptional regulator
GCU45_RS30400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCU45_RS30405	COG3180	Ammonia monooxygenase
GCU45_RS30410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCU45_RS30415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GCU45_RS30450	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GCU45_RS30455	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS30465	COG0492	ferredoxin-NADP+ reductase activity
GCU45_RS30485	COG1472	Belongs to the glycosyl hydrolase 3 family
GCU45_RS30500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GCU45_RS30505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCU45_RS30510	COG0671	phosphoesterase, PA-phosphatase related
GCU45_RS30515	COG0586	Pfam SNARE associated Golgi protein
GCU45_RS30520	COG0673	inositol 2-dehydrogenase activity
GCU45_RS30525	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS30525	COG4977	sequence-specific DNA binding
GCU45_RS30530	COG0673	inositol 2-dehydrogenase activity
GCU45_RS30535	COG2032	superoxide dismutase activity
GCU45_RS30550	COG3119	arylsulfatase activity
GCU45_RS30555	COG4209	transmembrane transport
GCU45_RS30560	COG0395	ABC-type sugar transport system, permease component
GCU45_RS30570	COG3275	phosphorelay sensor kinase activity
GCU45_RS30580	COG0583	DNA-binding transcription factor activity
GCU45_RS30585	COG0697	spore germination
GCU45_RS30610	COG0656	L-ascorbic acid biosynthetic process
GCU45_RS30615	COG2814	Major facilitator Superfamily
GCU45_RS30620	COG1733	regulation of RNA biosynthetic process
GCU45_RS30625	COG2207	Transcriptional regulator
GCU45_RS30635	COG1609	Transcriptional regulator
GCU45_RS30645	COG1175	transmembrane transport
GCU45_RS30650	COG0395	ABC-type sugar transport system, permease component
GCU45_RS30655	COG1501	Belongs to the glycosyl hydrolase 31 family
GCU45_RS30660	COG0528	UMP kinase activity
GCU45_RS30665	COG0477	Major facilitator Superfamily
GCU45_RS30670	COG1063	alcohol dehydrogenase
GCU45_RS30675	COG1309	transcriptional regulator
GCU45_RS30680	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS30695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU45_RS30705	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GCU45_RS30720	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS30735	COG5002	protein histidine kinase activity
GCU45_RS30760	COG5577	PFAM Coat F domain
GCU45_RS30765	COG1063	alcohol dehydrogenase
GCU45_RS30775	COG5577	PFAM Coat F domain
GCU45_RS30780	COG0025	NhaP-type Na H and K H
GCU45_RS30785	COG1073	alpha beta
GCU45_RS30795	COG2814	Major facilitator Superfamily
GCU45_RS30810	COG4209	transmembrane transport
GCU45_RS30815	COG0395	ABC-type sugar transport system, permease component
GCU45_RS30825	COG2972	Histidine kinase
GCU45_RS30830	COG2207	Transcriptional regulator
GCU45_RS30830	COG4753	response regulator
GCU45_RS30835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCU45_RS30855	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GCU45_RS30860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GCU45_RS30865	COG0351	phosphomethylpyrimidine kinase
GCU45_RS30870	COG2272	Belongs to the type-B carboxylesterase lipase family
GCU45_RS30885	COG1051	belongs to the nudix hydrolase family
GCU45_RS30895	COG1522	sequence-specific DNA binding
GCU45_RS30900	COG1902	pentaerythritol trinitrate reductase activity
GCU45_RS30915	COG0667	Aldo Keto reductase
GCU45_RS30920	COG1368	sulfuric ester hydrolase activity
GCU45_RS30925	COG1846	Transcriptional regulator
GCU45_RS30935	COG0640	Transcriptional regulator
GCU45_RS30940	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GCU45_RS30950	COG4257	antibiotic catabolic process
GCU45_RS30960	COG0596	Alpha beta hydrolase
GCU45_RS30975	COG0697	spore germination
GCU45_RS30980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS30990	COG3961	Belongs to the TPP enzyme family
GCU45_RS31035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCU45_RS31045	COG1609	Transcriptional regulator
GCU45_RS31060	COG4753	response regulator
GCU45_RS31060	COG2207	Transcriptional regulator
GCU45_RS31070	COG4209	transmembrane transport
GCU45_RS31075	COG0395	ABC-type sugar transport system, permease component
GCU45_RS31080	COG1653	transport
GCU45_RS31105	COG0673	inositol 2-dehydrogenase activity
GCU45_RS31110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCU45_RS31125	COG1111	helicase
GCU45_RS31125	COG1205	dead DEAH box helicase
GCU45_RS31135	COG1309	transcriptional regulator
GCU45_RS31140	COG1073	alpha beta
GCU45_RS31160	COG4209	transmembrane transport
GCU45_RS31165	COG0395	ABC-type sugar transport system, permease component
GCU45_RS31170	COG2169	Transcriptional regulator
GCU45_RS31195	COG2814	Major facilitator Superfamily
GCU45_RS31200	COG0583	DNA-binding transcription factor activity
GCU45_RS31205	COG0640	Transcriptional regulator
GCU45_RS31220	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS31220	COG4977	sequence-specific DNA binding
GCU45_RS31230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GCU45_RS31235	COG1063	alcohol dehydrogenase
GCU45_RS31245	COG2814	Major facilitator Superfamily
GCU45_RS31250	COG0436	Aminotransferase
GCU45_RS31270	COG1116	anion transmembrane transporter activity
GCU45_RS31275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU45_RS31300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCU45_RS31315	COG1959	2 iron, 2 sulfur cluster binding
GCU45_RS31325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS31335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCU45_RS31340	COG1494	fructose-1,6-bisphosphatase
GCU45_RS31345	COG2226	methyltransferase
GCU45_RS31365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS31370	COG0768	penicillin binding
GCU45_RS31385	COG2124	cytochrome p450
GCU45_RS31390	COG1653	transport
GCU45_RS31395	COG4209	transmembrane transport
GCU45_RS31400	COG0395	ABC-type sugar transport system, permease component
GCU45_RS31410	COG0662	Cupin 2, conserved barrel domain protein
GCU45_RS31410	COG2207	Transcriptional regulator
GCU45_RS31415	COG1653	transport
GCU45_RS31440	COG1357	PFAM Pentapeptide repeats (8 copies)
GCU45_RS31445	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GCU45_RS31465	COG0697	spore germination
GCU45_RS31480	COG0673	inositol 2-dehydrogenase activity
GCU45_RS31485	COG3962	Belongs to the TPP enzyme family
GCU45_RS31490	COG1082	Xylose isomerase domain protein TIM barrel
GCU45_RS31495	COG3718	enzyme involved in inositol metabolism
GCU45_RS31500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCU45_RS31505	COG1012	belongs to the aldehyde dehydrogenase family
GCU45_RS31510	COG1609	Transcriptional regulator
GCU45_RS31515	COG4209	transmembrane transport
GCU45_RS31525	COG0395	ABC-type sugar transport system, permease component
GCU45_RS31545	COG0456	acetyltransferase
GCU45_RS31550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCU45_RS31555	COG0583	DNA-binding transcription factor activity
GCU45_RS31560	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS31570	COG3711	transcriptional antiterminator
GCU45_RS31580	COG0246	Mannitol dehydrogenase
GCU45_RS31590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCU45_RS31590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCU45_RS31595	COG1132	(ABC) transporter
GCU45_RS31605	COG2124	cytochrome p450
GCU45_RS31615	COG4209	transmembrane transport
GCU45_RS31620	COG0395	ABC-type sugar transport system, permease component
GCU45_RS31635	COG1802	Transcriptional regulator
GCU45_RS31645	COG3250	beta-galactosidase activity
GCU45_RS31655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS31665	COG0405	Gamma-glutamyltransferase
GCU45_RS31670	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS31670	COG2207	Transcriptional regulator
GCU45_RS31675	COG0697	spore germination
GCU45_RS31680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCU45_RS31685	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GCU45_RS31725	COG3706	GGDEF domain
GCU45_RS31735	COG1070	Carbohydrate kinase
GCU45_RS31740	COG4806	L-rhamnose isomerase
GCU45_RS31750	COG2972	Histidine kinase
GCU45_RS31770	COG0395	ABC-type sugar transport system, permease component
GCU45_RS31785	COG2112	serine threonine protein kinase
GCU45_RS31795	COG3118	belongs to the thioredoxin family
GCU45_RS31805	COG0662	Cupin 2, conserved barrel domain protein
GCU45_RS31815	COG4209	transmembrane transport
GCU45_RS31820	COG0395	ABC-type sugar transport system, permease component
GCU45_RS31825	COG1653	transport
GCU45_RS31830	COG4753	response regulator
GCU45_RS31830	COG2207	Transcriptional regulator
GCU45_RS31840	COG1653	transport
GCU45_RS31880	COG0697	spore germination
GCU45_RS31885	COG1902	pentaerythritol trinitrate reductase activity
GCU45_RS31895	COG0492	ferredoxin-NADP+ reductase activity
GCU45_RS31920	COG2267	carboxylic ester hydrolase activity
GCU45_RS31925	COG1309	transcriptional regulator
GCU45_RS31935	COG0004	ammonium transporteR
GCU45_RS31945	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS31945	COG2169	Transcriptional regulator
GCU45_RS31955	COG0667	Aldo Keto reductase
GCU45_RS31960	COG1063	alcohol dehydrogenase
GCU45_RS31970	COG4209	transmembrane transport
GCU45_RS31975	COG0395	ABC-type sugar transport system, permease component
GCU45_RS31990	COG1917	Cupin 2, conserved barrel domain protein
GCU45_RS31990	COG4977	sequence-specific DNA binding
GCU45_RS31995	COG0673	inositol 2-dehydrogenase activity
GCU45_RS32000	COG3275	phosphorelay sensor kinase activity
GCU45_RS32010	COG1175	transmembrane transport
GCU45_RS32015	COG0395	ABC-type sugar transport system, permease component
GCU45_RS32020	COG1653	transport
GCU45_RS32040	COG0840	transmembrane signaling receptor activity
GCU45_RS32065	COG1116	anion transmembrane transporter activity
GCU45_RS32070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU45_RS32075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU45_RS32095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GCU45_RS32105	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GCU45_RS32115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GCU45_RS32145	COG3118	belongs to the thioredoxin family
GCU45_RS32150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GCU45_RS32155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCU45_RS32165	COG4221	oxidoreductase activity
GCU45_RS32175	COG4977	sequence-specific DNA binding
GCU45_RS32185	COG0640	Transcriptional regulator
GCU45_RS32190	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS32200	COG0583	DNA-binding transcription factor activity
GCU45_RS32215	COG3119	arylsulfatase activity
GCU45_RS32225	COG0583	DNA-binding transcription factor activity
GCU45_RS32230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GCU45_RS32235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GCU45_RS32240	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GCU45_RS32250	COG0583	DNA-binding transcription factor activity
GCU45_RS32255	COG2329	Antibiotic biosynthesis monooxygenase
GCU45_RS32265	COG1940	carbohydrate kinase activity
GCU45_RS32270	COG1904	glucuronate isomerase
GCU45_RS32280	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS32285	COG1606	tRNA processing
GCU45_RS32290	COG1691	(AIR) carboxylase
GCU45_RS32295	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GCU45_RS32300	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GCU45_RS32305	COG0154	amidase activity
GCU45_RS32310	COG0697	spore germination
GCU45_RS32340	COG0583	DNA-binding transcription factor activity
GCU45_RS32360	COG0745	RESPONSE REGULATOR receiver
GCU45_RS32370	COG0702	epimerase
GCU45_RS32385	COG2376	Dihydroxyacetone kinase
GCU45_RS32395	COG2373	Large extracellular alpha-helical protein
GCU45_RS32410	COG2972	Histidine kinase
GCU45_RS32415	COG4753	response regulator
GCU45_RS32415	COG2207	Transcriptional regulator
GCU45_RS32420	COG2182	Extracellular solute-binding protein
GCU45_RS32425	COG1175	transmembrane transport
GCU45_RS32430	COG0395	ABC-type sugar transport system, permease component
GCU45_RS32435	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GCU45_RS32475	COG0745	RESPONSE REGULATOR receiver
GCU45_RS32480	COG5002	protein histidine kinase activity
GCU45_RS32485	COG0577	efflux transmembrane transporter activity
GCU45_RS32490	COG1136	(ABC) transporter
GCU45_RS32495	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GCU45_RS32500	COG2207	Transcriptional regulator
GCU45_RS32505	COG1164	Oligoendopeptidase f
GCU45_RS32515	COG2050	protein possibly involved in aromatic compounds catabolism
GCU45_RS32525	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS32525	COG0604	alcohol dehydrogenase
GCU45_RS32525	COG3321	synthase
GCU45_RS32535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCU45_RS32540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCU45_RS32550	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS32555	COG1846	Transcriptional regulator
GCU45_RS32560	COG1473	amidohydrolase
GCU45_RS32565	COG4619	ABC transporter
GCU45_RS32570	COG0390	transport system, permease component
GCU45_RS32580	COG0791	NLP P60 protein
GCU45_RS32585	COG0745	RESPONSE REGULATOR receiver
GCU45_RS32590	COG5002	protein histidine kinase activity
GCU45_RS32600	COG3511	phospholipase C
GCU45_RS32605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GCU45_RS32615	COG0586	Pfam SNARE associated Golgi protein
GCU45_RS32625	COG0556	nucleotide-excision repair
GCU45_RS32635	COG0494	nUDIX hydrolase
GCU45_RS32640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GCU45_RS32650	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GCU45_RS32680	COG0531	amino acid
GCU45_RS32690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCU45_RS32695	COG3973	AAA domain
GCU45_RS32700	COG0494	nUDIX hydrolase
GCU45_RS32725	COG1309	transcriptional regulator
GCU45_RS32735	COG1136	(ABC) transporter
GCU45_RS32740	COG0577	efflux transmembrane transporter activity
GCU45_RS32745	COG5294	Protein conserved in bacteria
GCU45_RS32755	COG0745	RESPONSE REGULATOR receiver
GCU45_RS32760	COG2205	protein histidine kinase activity
GCU45_RS32770	COG0596	Alpha beta hydrolase
GCU45_RS32780	COG2720	vancomycin resistance protein
GCU45_RS32785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCU45_RS32825	COG4977	sequence-specific DNA binding
GCU45_RS32830	COG4209	transmembrane transport
GCU45_RS32835	COG0395	ABC-type sugar transport system, permease component
GCU45_RS32855	COG3250	beta-galactosidase activity
GCU45_RS32865	COG0753	catalase activity
GCU45_RS32870	COG0494	nUDIX hydrolase
GCU45_RS32880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCU45_RS32895	COG3507	Belongs to the glycosyl hydrolase 43 family
GCU45_RS32915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GCU45_RS32925	COG1472	Belongs to the glycosyl hydrolase 3 family
GCU45_RS32930	COG2207	Transcriptional regulator
GCU45_RS32935	COG0346	lactoylglutathione lyase activity
GCU45_RS32945	COG0456	acetyltransferase
GCU45_RS32950	COG0494	nUDIX hydrolase
GCU45_RS32970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCU45_RS32975	COG2146	nitrite reductase [NAD(P)H] activity
GCU45_RS33010	COG0745	RESPONSE REGULATOR receiver
GCU45_RS33015	COG2205	protein histidine kinase activity
GCU45_RS33020	COG2972	Histidine kinase
GCU45_RS33025	COG2197	response regulator
GCU45_RS33030	COG1653	transport
GCU45_RS33035	COG4209	transmembrane transport
GCU45_RS33040	COG0395	ABC-type sugar transport system, permease component
GCU45_RS33050	COG3250	beta-galactosidase activity
GCU45_RS33070	COG2814	Major facilitator Superfamily
GCU45_RS33075	COG1309	transcriptional regulator
GCU45_RS33080	COG0793	Belongs to the peptidase S41A family
GCU45_RS33085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCU45_RS33090	COG1120	ATPase activity
GCU45_RS33110	COG5002	protein histidine kinase activity
GCU45_RS33115	COG0028	Belongs to the TPP enzyme family
GCU45_RS33125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GCU45_RS33135	COG0702	epimerase
GCU45_RS33165	COG4753	response regulator
GCU45_RS33165	COG2207	Transcriptional regulator
GCU45_RS33170	COG2972	Histidine kinase
GCU45_RS33180	COG0395	ABC-type sugar transport system, permease component
GCU45_RS33185	COG4209	transmembrane transport
GCU45_RS33205	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GCU45_RS33210	COG1757	Na H antiporter
GCU45_RS33215	COG0251	oxidation-reduction process
GCU45_RS33220	COG0778	Nitroreductase
GCU45_RS33250	COG2972	Histidine kinase
GCU45_RS33260	COG1175	transmembrane transport
GCU45_RS33265	COG0395	ABC-type sugar transport system, permease component
GCU45_RS33270	COG0006	proline dipeptidase activity
GCU45_RS33280	COG3938	Belongs to the proline racemase family
GCU45_RS33290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCU45_RS33295	COG1012	belongs to the aldehyde dehydrogenase family
GCU45_RS33325	COG2084	Dehydrogenase
GCU45_RS33330	COG0583	DNA-binding transcription factor activity
GCU45_RS33335	COG1309	transcriptional regulator
GCU45_RS33350	COG0745	RESPONSE REGULATOR receiver
GCU45_RS33355	COG2205	protein histidine kinase activity
GCU45_RS33365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GCU45_RS33365	COG2755	lipolytic protein G-D-S-L family
GCU45_RS33395	COG1846	Transcriptional regulator
GCU45_RS33400	COG2814	Major facilitator Superfamily
GCU45_RS33405	COG2972	Histidine kinase
GCU45_RS33410	COG4753	response regulator
GCU45_RS33410	COG2207	Transcriptional regulator
GCU45_RS33420	COG1175	transmembrane transport
GCU45_RS33425	COG0395	ABC-type sugar transport system, permease component
GCU45_RS33440	COG3119	arylsulfatase activity
GCU45_RS33445	COG0673	inositol 2-dehydrogenase activity
GCU45_RS33450	COG0529	Catalyzes the synthesis of activated sulfate
GCU45_RS33455	COG3119	arylsulfatase activity
GCU45_RS33460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCU45_RS33460	COG2207	Transcriptional regulator
GCU45_RS33465	COG3119	arylsulfatase activity
GCU45_RS33470	COG4974	Belongs to the 'phage' integrase family
GCU45_RS33480	COG1733	regulation of RNA biosynthetic process
GCU45_RS33485	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCU45_RS33490	COG0778	Nitroreductase
GCU45_RS33500	COG1522	sequence-specific DNA binding
GCU45_RS33505	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GCU45_RS33515	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GCU45_RS33520	COG2086	electron transfer activity
GCU45_RS33525	COG1309	transcriptional regulator
GCU45_RS33530	COG0247	lactate metabolic process
GCU45_RS33530	COG2181	nitrate reductase activity
GCU45_RS33535	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCU45_RS33535	COG1024	Enoyl-CoA hydratase
GCU45_RS33540	COG0183	Belongs to the thiolase family
GCU45_RS33545	COG1960	acyl-CoA dehydrogenase activity
GCU45_RS33550	COG0318	PFAM AMP-dependent synthetase and ligase
GCU45_RS33565	COG1028	Short-chain dehydrogenase reductase Sdr
GCU45_RS33575	COG3119	arylsulfatase activity
GCU45_RS33585	COG3397	chitin binding
GCU45_RS33595	COG1309	transcriptional regulator
GCU45_RS33600	COG0477	Major facilitator Superfamily
GCU45_RS33615	COG2378	regulation of single-species biofilm formation
GCU45_RS33625	COG2223	nitrite transmembrane transporter activity
GCU45_RS33630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCU45_RS33635	COG0243	molybdopterin cofactor binding
GCU45_RS33645	COG0789	Transcriptional regulator
GCU45_RS33655	COG2076	Multidrug Resistance protein
GCU45_RS33665	COG1653	transport
GCU45_RS33670	COG4209	transmembrane transport