locus-tag	class	description
FOA15_RS00060	COG0702	epimerase
FOA15_RS00075	COG1801	Protein of unknown function DUF72
FOA15_RS00080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FOA15_RS00080	COG2755	lipolytic protein G-D-S-L family
FOA15_RS00090	COG0840	transmembrane signaling receptor activity
FOA15_RS00100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOA15_RS00105	COG0500	methyltransferase
FOA15_RS00140	COG2197	response regulator
FOA15_RS00145	COG2822	iron ion transport
FOA15_RS00150	COG2837	iron assimilation
FOA15_RS00155	COG0672	)-iron permease
FOA15_RS00200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOA15_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOA15_RS00220	COG1737	Transcriptional regulator
FOA15_RS00230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOA15_RS00275	COG0789	Transcriptional regulator
FOA15_RS00275	COG4978	Transcriptional regulator
FOA15_RS00280	COG1811	Na channel or pump
FOA15_RS00295	COG2190	(PTS) system
FOA15_RS00295	COG1263	PTS System
FOA15_RS00295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS00315	COG0438	transferase activity, transferring glycosyl groups
FOA15_RS00325	COG0463	Glycosyl transferase, family 2
FOA15_RS00325	COG1216	Glycosyl transferase, family 2
FOA15_RS00330	COG1215	transferase activity, transferring glycosyl groups
FOA15_RS00350	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOA15_RS00355	COG1086	Polysaccharide biosynthesis protein
FOA15_RS00405	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOA15_RS00410	COG1216	Glycosyl transferase, family 2
FOA15_RS00420	COG0463	Glycosyl transferase, family 2
FOA15_RS00425	COG3227	Zinc metalloprotease (Elastase)
FOA15_RS00430	COG3227	Zinc metalloprotease (Elastase)
FOA15_RS00435	COG3227	Zinc metalloprotease (Elastase)
FOA15_RS00445	COG0297	glycogen (starch) synthase activity
FOA15_RS00455	COG0688	phosphatidylethanolamine metabolic process
FOA15_RS00485	COG1131	(ABC) transporter
FOA15_RS00495	COG0300	oxidoreductase activity
FOA15_RS00505	COG0583	DNA-binding transcription factor activity
FOA15_RS00510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOA15_RS00515	COG2357	RelA SpoT domain protein
FOA15_RS00545	COG1408	metallophosphoesterase
FOA15_RS00550	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOA15_RS00555	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOA15_RS00560	COG1053	succinate dehydrogenase
FOA15_RS00565	COG2009	succinate dehydrogenase
FOA15_RS00570	COG0583	DNA-binding transcription factor activity
FOA15_RS00575	COG0569	domain protein
FOA15_RS00580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOA15_RS00590	COG0322	excinuclease ABC activity
FOA15_RS00595	COG3118	belongs to the thioredoxin family
FOA15_RS00600	COG1484	DNA-dependent DNA replication
FOA15_RS00630	COG1252	NADH dehydrogenase
FOA15_RS00635	COG0492	ferredoxin-NADP+ reductase activity
FOA15_RS00645	COG0189	ligase activity
FOA15_RS00650	COG0248	Ppx GppA phosphatase
FOA15_RS00655	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOA15_RS00665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOA15_RS00670	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FOA15_RS00685	COG0697	spore germination
FOA15_RS00690	COG0583	DNA-binding transcription factor activity
FOA15_RS00705	COG3397	chitin binding
FOA15_RS00710	COG0316	Belongs to the HesB IscA family
FOA15_RS00715	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FOA15_RS00720	COG1252	NADH dehydrogenase
FOA15_RS00730	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOA15_RS00735	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS00740	COG1464	Belongs to the NlpA lipoprotein family
FOA15_RS00745	COG2011	ABC-type metal ion transport system permease component
FOA15_RS00750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOA15_RS00760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOA15_RS00765	COG1612	heme a metabolic process
FOA15_RS00770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOA15_RS00775	COG2226	methyltransferase
FOA15_RS00780	COG1120	ATPase activity
FOA15_RS00805	COG2839	Protein conserved in bacteria
FOA15_RS00810	COG0561	phosphatase activity
FOA15_RS00815	COG0768	penicillin binding
FOA15_RS00820	COG0768	penicillin binding
FOA15_RS00840	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOA15_RS00845	COG0109	protoheme IX farnesyltransferase activity
FOA15_RS00850	COG1988	membrane-bound metal-dependent
FOA15_RS00870	COG0180	Tryptophanyl-tRNA synthetase
FOA15_RS00895	COG3093	addiction module antidote protein HigA
FOA15_RS00905	COG2346	COG2346, Truncated hemoglobins
FOA15_RS00910	COG3314	Sporulation integral membrane protein YlbJ
FOA15_RS00915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOA15_RS00920	COG4470	Protein conserved in bacteria
FOA15_RS00930	COG0739	heme binding
FOA15_RS00940	COG0667	Aldo Keto reductase
FOA15_RS00950	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOA15_RS00960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOA15_RS00965	COG2169	Transcriptional regulator
FOA15_RS00970	COG1115	amino acid carrier protein
FOA15_RS00980	COG3711	transcriptional antiterminator
FOA15_RS00985	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS00990	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOA15_RS00995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOA15_RS01000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOA15_RS01030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOA15_RS01035	COG0569	domain protein
FOA15_RS01045	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOA15_RS01050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOA15_RS01065	COG2197	response regulator
FOA15_RS01070	COG4585	Histidine kinase
FOA15_RS01080	COG1842	Phage shock protein A
FOA15_RS01090	COG1842	Phage shock protein A
FOA15_RS01100	COG2814	Major facilitator Superfamily
FOA15_RS01110	COG2226	methyltransferase
FOA15_RS01220	COG3858	chitin binding
FOA15_RS01225	COG0735	belongs to the Fur family
FOA15_RS01240	COG1285	pathogenesis
FOA15_RS01245	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOA15_RS01245	COG0456	acetyltransferase
FOA15_RS01250	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOA15_RS01255	COG0154	amidase activity
FOA15_RS01260	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOA15_RS01275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOA15_RS01285	COG0586	Pfam SNARE associated Golgi protein
FOA15_RS01310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOA15_RS01320	COG4840	Belongs to the UPF0435 family
FOA15_RS01340	COG1191	sigma factor activity
FOA15_RS01345	COG2172	sigma factor antagonist activity
FOA15_RS01355	COG3437	response regulator, receiver
FOA15_RS01355	COG3850	Histidine kinase
FOA15_RS01355	COG4999	Histidine kinase
FOA15_RS01355	COG2205	protein histidine kinase activity
FOA15_RS01360	COG2208	phosphoserine phosphatase activity
FOA15_RS01380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOA15_RS01390	COG0488	(ABC) transporter
FOA15_RS01395	COG1120	ATPase activity
FOA15_RS01410	COG5386	Cell surface protein
FOA15_RS01415	COG5386	Cell surface protein
FOA15_RS01420	COG5386	Cell surface protein
FOA15_RS01430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS01440	COG2329	Antibiotic biosynthesis monooxygenase
FOA15_RS01445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOA15_RS01450	COG1294	oxidase, subunit
FOA15_RS01455	COG1271	oxidase subunit
FOA15_RS01460	COG1846	Transcriptional regulator
FOA15_RS01465	COG2814	Major facilitator Superfamily
FOA15_RS01470	COG1413	lyase activity
FOA15_RS01475	COG0833	amino acid
FOA15_RS01510	COG1070	Carbohydrate kinase
FOA15_RS01515	COG2115	Belongs to the xylose isomerase family
FOA15_RS01545	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOA15_RS01550	COG1566	PFAM secretion protein HlyD family protein
FOA15_RS01555	COG2814	Major facilitator Superfamily
FOA15_RS01560	COG2217	Heavy metal translocating P-type atpase
FOA15_RS01570	COG2217	Heavy metal translocating P-type atpase
FOA15_RS01575	COG0640	Transcriptional regulator
FOA15_RS01585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOA15_RS01595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOA15_RS01600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOA15_RS01610	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS01625	COG0395	ABC-type sugar transport system, permease component
FOA15_RS01630	COG4209	transmembrane transport
FOA15_RS01650	COG0444	Belongs to the ABC transporter superfamily
FOA15_RS01655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOA15_RS01660	COG0601	transmembrane transport
FOA15_RS01675	COG2197	response regulator
FOA15_RS01680	COG4585	Histidine kinase
FOA15_RS01685	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOA15_RS01690	COG4988	ABC transporter
FOA15_RS01695	COG1294	oxidase, subunit
FOA15_RS01700	COG1271	oxidase subunit
FOA15_RS01705	COG2207	Transcriptional regulator
FOA15_RS01705	COG4753	response regulator
FOA15_RS01710	COG2972	Histidine kinase
FOA15_RS01720	COG5039	Polysaccharide pyruvyl transferase
FOA15_RS01745	COG1253	flavin adenine dinucleotide binding
FOA15_RS01750	COG1968	undecaprenyl-diphosphatase activity
FOA15_RS01755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOA15_RS01760	COG0667	Aldo Keto reductase
FOA15_RS01765	COG2819	hydrolase of the alpha beta superfamily
FOA15_RS01770	COG4607	ABC-type enterochelin transport system periplasmic component
FOA15_RS01775	COG4604	ABC transporter, ATP-binding protein
FOA15_RS01785	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS01795	COG5002	protein histidine kinase activity
FOA15_RS01800	COG1136	(ABC) transporter
FOA15_RS01800	COG0577	efflux transmembrane transporter activity
FOA15_RS01815	COG1473	amidohydrolase
FOA15_RS01825	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOA15_RS01845	COG0346	lactoylglutathione lyase activity
FOA15_RS01855	COG0351	phosphomethylpyrimidine kinase
FOA15_RS01865	COG0737	Belongs to the 5'-nucleotidase family
FOA15_RS01870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOA15_RS01880	COG3639	organic phosphonate transmembrane transporter activity
FOA15_RS01890	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FOA15_RS01900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOA15_RS01910	COG4208	sulfate ABC transporter
FOA15_RS01920	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOA15_RS01945	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOA15_RS01950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOA15_RS01960	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOA15_RS01965	COG2390	Transcriptional regulator
FOA15_RS01985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOA15_RS01985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOA15_RS02000	COG1733	regulation of RNA biosynthetic process
FOA15_RS02005	COG1733	regulation of RNA biosynthetic process
FOA15_RS02030	COG2814	Major facilitator Superfamily
FOA15_RS02040	COG2169	Transcriptional regulator
FOA15_RS02050	COG0456	acetyltransferase
FOA15_RS02050	COG1846	Transcriptional regulator
FOA15_RS02055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOA15_RS02060	COG0640	Transcriptional regulator
FOA15_RS02070	COG0823	Involved in the tonB-independent uptake of proteins
FOA15_RS02070	COG1506	peptidase
FOA15_RS02070	COG4946	Tricorn protease homolog
FOA15_RS02075	COG4608	Belongs to the ABC transporter superfamily
FOA15_RS02080	COG0444	Belongs to the ABC transporter superfamily
FOA15_RS02090	COG0601	transmembrane transport
FOA15_RS02095	COG4533	DNA binding
FOA15_RS02100	COG1473	amidohydrolase
FOA15_RS02105	COG2186	Transcriptional regulator
FOA15_RS02120	COG1819	glycosyl
FOA15_RS02135	COG3959	Transketolase, thiamine diphosphate binding domain
FOA15_RS02140	COG3958	Transketolase
FOA15_RS02145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOA15_RS02150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS02150	COG3711	transcriptional antiterminator
FOA15_RS02155	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOA15_RS02165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOA15_RS02170	COG1349	DNA-binding transcription factor activity
FOA15_RS02175	COG0191	fructose-bisphosphate aldolase activity
FOA15_RS02180	COG1082	Xylose isomerase domain protein TIM barrel
FOA15_RS02185	COG3962	Belongs to the TPP enzyme family
FOA15_RS02190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOA15_RS02195	COG3718	enzyme involved in inositol metabolism
FOA15_RS02210	COG1349	DNA-binding transcription factor activity
FOA15_RS02215	COG1942	4-Oxalocrotonate Tautomerase
FOA15_RS02225	COG1082	Xylose isomerase domain protein TIM barrel
FOA15_RS02230	COG0673	inositol 2-dehydrogenase activity
FOA15_RS02235	COG2814	Major facilitator Superfamily
FOA15_RS02250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOA15_RS02280	COG3711	transcriptional antiterminator
FOA15_RS02285	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS02290	COG2190	(PTS) system
FOA15_RS02290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS02290	COG1263	PTS System
FOA15_RS02300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOA15_RS02310	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOA15_RS02315	COG5662	AntiSigma factor
FOA15_RS02320	COG1595	DNA-templated transcription, initiation
FOA15_RS02325	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOA15_RS02425	COG0726	polysaccharide deacetylase
FOA15_RS02435	COG0489	protein tyrosine kinase activity
FOA15_RS02440	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOA15_RS02450	COG0175	sulfate reduction
FOA15_RS02455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOA15_RS02460	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOA15_RS02465	COG0101	tRNA pseudouridine synthase activity
FOA15_RS02470	COG0203	ribosomal protein L17
FOA15_RS02475	COG0202	RNA polymerase activity
FOA15_RS02480	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOA15_RS02485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOA15_RS02490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOA15_RS02495	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOA15_RS02505	COG0024	Methionine aminopeptidase
FOA15_RS02510	COG0563	adenylate kinase activity
FOA15_RS02515	COG0201	protein transport
FOA15_RS02520	COG0200	Binds to the 23S rRNA
FOA15_RS02525	COG1841	ribosomal large subunit assembly
FOA15_RS02530	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOA15_RS02535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOA15_RS02540	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOA15_RS02550	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOA15_RS02555	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOA15_RS02560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOA15_RS02565	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOA15_RS02570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOA15_RS02575	COG0255	Belongs to the universal ribosomal protein uL29 family
FOA15_RS02580	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOA15_RS02585	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOA15_RS02590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOA15_RS02600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOA15_RS02605	COG0089	rRNA binding
FOA15_RS02610	COG0088	Forms part of the polypeptide exit tunnel
FOA15_RS02615	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOA15_RS02635	COG0049	tRNA binding
FOA15_RS02640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOA15_RS02645	COG1358	cellular component organization or biogenesis
FOA15_RS02650	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOA15_RS02655	COG0085	RNA polymerase activity
FOA15_RS02660	COG2813	Specifically methylates the guanine in position
FOA15_RS02665	COG0222	ribosome binding
FOA15_RS02670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOA15_RS02675	COG0081	regulation of translation
FOA15_RS02680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOA15_RS02685	COG0250	Participates in transcription elongation, termination and antitermination
FOA15_RS02690	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOA15_RS02695	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOA15_RS02705	COG3688	RNA-binding protein containing a PIN domain
FOA15_RS02710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOA15_RS02715	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FOA15_RS02720	COG0215	cysteine-tRNA ligase activity
FOA15_RS02725	COG1045	serine acetyltransferase
FOA15_RS02730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOA15_RS02735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOA15_RS02740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOA15_RS02745	COG4956	integral membrane protein (PIN domain superfamily)
FOA15_RS02750	COG1183	phosphatidylcholine synthase activity
FOA15_RS02755	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FOA15_RS02760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOA15_RS02765	COG0542	response to heat
FOA15_RS02770	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FOA15_RS02775	COG3880	PFAM UvrB UvrC protein
FOA15_RS02810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOA15_RS02815	COG0210	DNA helicase
FOA15_RS02820	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FOA15_RS02840	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOA15_RS02865	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOA15_RS02875	COG1216	Glycosyl transferase, family 2
FOA15_RS02875	COG0463	Glycosyl transferase, family 2
FOA15_RS02880	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOA15_RS02880	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOA15_RS02885	COG0367	asparagine synthase
FOA15_RS02895	COG1682	transport, permease protein
FOA15_RS02905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOA15_RS02910	COG0463	Glycosyl transferase, family 2
FOA15_RS02920	COG0826	peptidase U32
FOA15_RS02930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOA15_RS02935	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOA15_RS02945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOA15_RS02950	COG0556	nucleotide-excision repair
FOA15_RS02955	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOA15_RS02960	COG1360	Flagellar Motor Protein
FOA15_RS03005	COG1191	sigma factor activity
FOA15_RS03035	COG3409	Peptidoglycan-binding domain 1 protein
FOA15_RS03035	COG0793	Belongs to the peptidase S41A family
FOA15_RS03040	COG0739	heme binding
FOA15_RS03040	COG0741	lytic transglycosylase activity
FOA15_RS03040	COG1196	nuclear chromosome segregation
FOA15_RS03045	COG2177	Part of the ABC transporter FtsEX involved in
FOA15_RS03050	COG2884	Cell division ATP-binding protein ftsE
FOA15_RS03055	COG2720	vancomycin resistance protein
FOA15_RS03075	COG0463	Glycosyl transferase, family 2
FOA15_RS03090	COG0165	Argininosuccinate lyase
FOA15_RS03095	COG0137	argininosuccinate synthase activity
FOA15_RS03100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOA15_RS03110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOA15_RS03115	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOA15_RS03120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOA15_RS03125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOA15_RS03140	COG0653	protein targeting
FOA15_RS03155	COG1278	Cold shock
FOA15_RS03165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOA15_RS03185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOA15_RS03200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOA15_RS03210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOA15_RS03215	COG2089	acid synthase
FOA15_RS03225	COG1086	Polysaccharide biosynthesis protein
FOA15_RS03245	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOA15_RS03255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOA15_RS03265	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FOA15_RS03270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOA15_RS03275	COG1256	bacterial-type flagellum assembly
FOA15_RS03275	COG4786	Flagellar basal body rod
FOA15_RS03295	COG1388	LysM domain
FOA15_RS03305	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOA15_RS03340	COG1309	transcriptional regulator
FOA15_RS03345	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOA15_RS03370	COG1566	PFAM secretion protein HlyD family protein
FOA15_RS03385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOA15_RS03405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOA15_RS03410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOA15_RS03425	COG4786	Flagellar basal body rod
FOA15_RS03435	COG1609	Transcriptional regulator
FOA15_RS03440	COG0739	heme binding
FOA15_RS03445	COG2385	sporulation resulting in formation of a cellular spore
FOA15_RS03450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOA15_RS03460	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOA15_RS03465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOA15_RS03470	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOA15_RS03475	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOA15_RS03480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOA15_RS03485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOA15_RS03495	COG0356	it plays a direct role in the translocation of protons across the membrane
FOA15_RS03510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOA15_RS03515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOA15_RS03520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOA15_RS03535	COG1971	Probably functions as a manganese efflux pump
FOA15_RS03540	COG0009	L-threonylcarbamoyladenylate synthase
FOA15_RS03550	COG0772	Belongs to the SEDS family
FOA15_RS03560	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOA15_RS03595	COG0012	GTP binding
FOA15_RS03600	COG0456	acetyltransferase
FOA15_RS03605	COG1304	FMN binding
FOA15_RS03630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOA15_RS03640	COG2076	Multidrug Resistance protein
FOA15_RS03645	COG2076	Multidrug Resistance protein
FOA15_RS03655	COG1522	sequence-specific DNA binding
FOA15_RS03670	COG1279	arginine transmembrane transporter activity
FOA15_RS03675	COG0746	molybdenum cofactor guanylyltransferase activity
FOA15_RS03695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOA15_RS03715	COG2814	Major facilitator Superfamily
FOA15_RS03720	COG0243	molybdopterin cofactor binding
FOA15_RS03725	COG2116	formate transmembrane transporter activity
FOA15_RS03730	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOA15_RS03735	COG0386	Belongs to the glutathione peroxidase family
FOA15_RS03740	COG1120	ATPase activity
FOA15_RS03750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOA15_RS03755	COG0628	permease
FOA15_RS03765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOA15_RS03790	COG1114	Component of the transport system for branched-chain amino acids
FOA15_RS03810	COG0300	oxidoreductase activity
FOA15_RS03815	COG0110	maltose O-acetyltransferase activity
FOA15_RS03820	COG0789	Transcriptional regulator
FOA15_RS03830	COG4149	molybdate abc transporter
FOA15_RS03835	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOA15_RS03840	COG1910	domain protein
FOA15_RS03865	COG1126	abc transporter atp-binding protein
FOA15_RS03870	COG0765	amino acid transport
FOA15_RS03875	COG0765	amino acid transport
FOA15_RS03880	COG0659	secondary active sulfate transmembrane transporter activity
FOA15_RS03890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOA15_RS03905	COG2002	toxin-antitoxin pair type II binding
FOA15_RS03935	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FOA15_RS03960	COG1611	Belongs to the LOG family
FOA15_RS03965	COG1587	Uroporphyrinogen-III synthase
FOA15_RS03985	COG0697	spore germination
FOA15_RS04035	COG0697	spore germination
FOA15_RS04045	COG2259	Doxx family
FOA15_RS04060	COG0745	RESPONSE REGULATOR receiver
FOA15_RS04070	COG3706	GGDEF domain
FOA15_RS04080	COG1472	Belongs to the glycosyl hydrolase 3 family
FOA15_RS04085	COG2002	toxin-antitoxin pair type II binding
FOA15_RS04095	COG0602	queuosine metabolic process
FOA15_RS04100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOA15_RS04110	COG0300	oxidoreductase activity
FOA15_RS04125	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOA15_RS04130	COG0783	Belongs to the Dps family
FOA15_RS04135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOA15_RS04140	COG3842	ATPase activity
FOA15_RS04150	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOA15_RS04220	COG1846	Transcriptional regulator
FOA15_RS04225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOA15_RS04225	COG1199	ATP-dependent helicase activity
FOA15_RS04230	COG3706	GGDEF domain
FOA15_RS04240	COG0583	DNA-binding transcription factor activity
FOA15_RS04245	COG1380	Effector of murein hydrolase LrgA
FOA15_RS04250	COG1346	cytolysis
FOA15_RS04255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOA15_RS04260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOA15_RS04270	COG2910	NAD(P)H-binding
FOA15_RS04290	COG0745	RESPONSE REGULATOR receiver
FOA15_RS04295	COG2807	transmembrane transport
FOA15_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS04310	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FOA15_RS04315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOA15_RS04320	COG1609	Transcriptional regulator
FOA15_RS04325	COG0534	Mate efflux family protein
FOA15_RS04330	COG0604	alcohol dehydrogenase
FOA15_RS04335	COG0395	ABC-type sugar transport system, permease component
FOA15_RS04340	COG1175	transmembrane transport
FOA15_RS04345	COG1653	transport
FOA15_RS04350	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FOA15_RS04360	COG0488	(ABC) transporter
FOA15_RS04370	COG2814	Major facilitator Superfamily
FOA15_RS04375	COG3458	cephalosporin-C deacetylase activity
FOA15_RS04380	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FOA15_RS04385	COG0395	ABC-type sugar transport system, permease component
FOA15_RS04395	COG2182	Extracellular solute-binding protein
FOA15_RS04400	COG2942	2-epimerase
FOA15_RS04405	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FOA15_RS04420	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FOA15_RS04425	COG0504	CTP synthase activity
FOA15_RS04440	COG1252	NADH dehydrogenase
FOA15_RS04460	COG0588	phosphoglycerate mutase activity
FOA15_RS04495	COG2002	toxin-antitoxin pair type II binding
FOA15_RS04520	COG1609	Transcriptional regulator
FOA15_RS04525	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOA15_RS04535	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOA15_RS04540	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOA15_RS04545	COG3693	PFAM glycoside hydrolase, family 10
FOA15_RS04550	COG0395	ABC-type sugar transport system, permease component
FOA15_RS04555	COG4209	transmembrane transport
FOA15_RS04605	COG2972	Histidine kinase
FOA15_RS04605	COG0745	RESPONSE REGULATOR receiver
FOA15_RS04610	COG4753	response regulator
FOA15_RS04610	COG2207	Transcriptional regulator
FOA15_RS04635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOA15_RS04640	COG1773	rubredoxin
FOA15_RS04645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOA15_RS04655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOA15_RS04665	COG0702	epimerase
FOA15_RS04670	COG1309	transcriptional regulator
FOA15_RS04675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOA15_RS04680	COG0390	transport system, permease component
FOA15_RS04685	COG0402	S-adenosylhomocysteine deaminase activity
FOA15_RS04725	COG1522	sequence-specific DNA binding
FOA15_RS04730	COG2814	Major facilitator Superfamily
FOA15_RS04735	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS04755	COG1874	Beta-galactosidase
FOA15_RS04755	COG0366	Alpha amylase catalytic
FOA15_RS04760	COG1902	pentaerythritol trinitrate reductase activity
FOA15_RS04770	COG2207	Transcriptional regulator
FOA15_RS04770	COG4753	response regulator
FOA15_RS04775	COG2972	Histidine kinase
FOA15_RS04790	COG0523	cobalamin synthesis protein
FOA15_RS04810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOA15_RS04820	COG2755	lipolytic protein G-D-S-L family
FOA15_RS04820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOA15_RS04825	COG0733	neurotransmitter:sodium symporter activity
FOA15_RS04835	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOA15_RS04840	COG3177	Filamentation induced by cAMP protein fic
FOA15_RS04850	COG0647	UMP catabolic process
FOA15_RS04860	COG3842	ATPase activity
FOA15_RS04870	COG1177	transmembrane transport
FOA15_RS04875	COG1840	ABC-type Fe3 transport system, periplasmic component
FOA15_RS04880	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOA15_RS04890	COG2188	Transcriptional regulator
FOA15_RS04895	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS04900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOA15_RS04905	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOA15_RS04910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOA15_RS04945	COG2378	regulation of single-species biofilm formation
FOA15_RS04955	COG0814	amino acid
FOA15_RS04960	COG1760	l-serine dehydratase
FOA15_RS04965	COG1760	l-serine dehydratase
FOA15_RS04970	COG2964	Protein conserved in bacteria
FOA15_RS05000	COG2378	regulation of single-species biofilm formation
FOA15_RS05010	COG0252	asparaginase activity
FOA15_RS05025	COG1126	abc transporter atp-binding protein
FOA15_RS05030	COG0765	amino acid transport
FOA15_RS05035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOA15_RS05040	COG4608	Belongs to the ABC transporter superfamily
FOA15_RS05055	COG0601	transmembrane transport
FOA15_RS05060	COG0747	negative chemotaxis
FOA15_RS05070	COG0444	Belongs to the ABC transporter superfamily
FOA15_RS05075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOA15_RS05085	COG0747	negative chemotaxis
FOA15_RS05090	COG2233	PERMEase
FOA15_RS05095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOA15_RS05105	COG4806	L-rhamnose isomerase
FOA15_RS05110	COG0235	Class ii aldolase
FOA15_RS05115	COG0662	Cupin 2, conserved barrel domain protein
FOA15_RS05115	COG2207	Transcriptional regulator
FOA15_RS05125	COG2040	homocysteine
FOA15_RS05135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOA15_RS05145	COG3290	protein histidine kinase activity
FOA15_RS05155	COG0167	dihydroorotate dehydrogenase activity
FOA15_RS05160	COG0543	2 iron, 2 sulfur cluster binding
FOA15_RS05165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOA15_RS05170	COG2207	Transcriptional regulator
FOA15_RS05170	COG3708	Transcriptional regulator
FOA15_RS05180	COG0386	Belongs to the glutathione peroxidase family
FOA15_RS05190	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS05220	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
FOA15_RS05220	COG0028	Belongs to the TPP enzyme family
FOA15_RS05225	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOA15_RS05240	COG5434	Belongs to the glycosyl hydrolase 28 family
FOA15_RS05250	COG0667	Aldo Keto reductase
FOA15_RS05255	COG0723	plastoquinol--plastocyanin reductase activity
FOA15_RS05255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOA15_RS05265	COG0667	Aldo Keto reductase
FOA15_RS05270	COG0535	radical SAM domain protein
FOA15_RS05285	COG2210	Belongs to the sulfur carrier protein TusA family
FOA15_RS05295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOA15_RS05300	COG1959	2 iron, 2 sulfur cluster binding
FOA15_RS05305	COG0702	epimerase
FOA15_RS05310	COG2824	Alkylphosphonate utilization operon protein PhnA
FOA15_RS05320	COG4589	Belongs to the CDS family
FOA15_RS05325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOA15_RS05325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOA15_RS05325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS05330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS05330	COG3711	transcriptional antiterminator
FOA15_RS05340	COG3835	regulator
FOA15_RS05345	COG1929	Belongs to the glycerate kinase type-1 family
FOA15_RS05350	COG2610	gluconate transmembrane transporter activity
FOA15_RS05390	COG0789	Transcriptional regulator
FOA15_RS05390	COG4978	Transcriptional regulator
FOA15_RS05395	COG0494	nUDIX hydrolase
FOA15_RS05400	COG3693	PFAM glycoside hydrolase, family 10
FOA15_RS05415	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FOA15_RS05420	COG0579	oxidoreductase
FOA15_RS05445	COG2273	Hydrolase Family 16
FOA15_RS05450	COG3266	domain, Protein
FOA15_RS05450	COG2911	Protein conserved in bacteria
FOA15_RS05450	COG1361	Conserved repeat domain
FOA15_RS05465	COG4509	Sortase family
FOA15_RS05495	COG0277	FAD linked oxidase domain protein
FOA15_RS05550	COG2226	methyltransferase
FOA15_RS05560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOA15_RS05570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOA15_RS05585	COG5002	protein histidine kinase activity
FOA15_RS05590	COG0745	RESPONSE REGULATOR receiver
FOA15_RS05595	COG0739	heme binding
FOA15_RS05605	COG2188	Transcriptional regulator
FOA15_RS05610	COG0587	DNA-directed DNA polymerase activity
FOA15_RS05635	COG3842	ATPase activity
FOA15_RS05650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOA15_RS05655	COG0305	Participates in initiation and elongation during chromosome replication
FOA15_RS05660	COG0359	binds to the 23S rRNA
FOA15_RS05665	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOA15_RS05685	COG1316	TRANSCRIPTIONal
FOA15_RS05690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOA15_RS05695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOA15_RS05700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOA15_RS05705	COG4608	Belongs to the ABC transporter superfamily
FOA15_RS05710	COG0444	Belongs to the ABC transporter superfamily
FOA15_RS05715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOA15_RS05720	COG0747	negative chemotaxis
FOA15_RS05725	COG0601	transmembrane transport
FOA15_RS05730	COG0583	DNA-binding transcription factor activity
FOA15_RS05735	COG1686	Belongs to the peptidase S11 family
FOA15_RS05740	COG4608	Belongs to the ABC transporter superfamily
FOA15_RS05745	COG0444	Belongs to the ABC transporter superfamily
FOA15_RS05750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOA15_RS05755	COG0601	transmembrane transport
FOA15_RS05760	COG4166	transmembrane transport
FOA15_RS05765	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOA15_RS05770	COG0629	single-stranded DNA binding
FOA15_RS05775	COG0360	Binds together with S18 to 16S ribosomal RNA
FOA15_RS05800	COG4481	Protein conserved in bacteria
FOA15_RS05805	COG0668	transmembrane transport
FOA15_RS05820	COG1475	DNA binding
FOA15_RS05825	COG1192	Involved in chromosome partitioning
FOA15_RS05830	COG1475	DNA binding
FOA15_RS05835	COG0357	Ribosomal RNA small subunit methyltransferase G
FOA15_RS05840	COG0445	tRNA wobble uridine modification
FOA15_RS05845	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOA15_RS05850	COG1847	R3H domain protein
FOA15_RS05855	COG0706	membrane insertase activity
FOA15_RS05860	COG0594	ribonuclease P activity
FOA15_RS05865	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOA15_RS05870	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOA15_RS05875	COG0592	DNA-directed DNA polymerase activity
FOA15_RS05880	COG2501	S4 domain
FOA15_RS05885	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOA15_RS05895	COG0187	DNA topoisomerase II activity
FOA15_RS05905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOA15_RS05910	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOA15_RS05945	COG1982	Orn Lys Arg decarboxylase major
FOA15_RS05950	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOA15_RS05955	COG3870	Protein conserved in bacteria
FOA15_RS05960	COG1728	Protein conserved in bacteria
FOA15_RS05965	COG0470	DNA polymerase III
FOA15_RS05970	COG1774	PSP1 C-terminal conserved region
FOA15_RS05975	COG4467	Involved in initiation control of chromosome replication
FOA15_RS05980	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOA15_RS05985	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOA15_RS05990	COG2002	toxin-antitoxin pair type II binding
FOA15_RS05995	COG1078	dGTPase activity
FOA15_RS06000	COG0084	hydrolase, TatD family'
FOA15_RS06005	COG3584	3D domain protein
FOA15_RS06005	COG3583	domain protein
FOA15_RS06015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOA15_RS06025	COG4466	Protein conserved in bacteria
FOA15_RS06035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOA15_RS06040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOA15_RS06045	COG2088	sporulation resulting in formation of a cellular spore
FOA15_RS06050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOA15_RS06055	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOA15_RS06060	COG0193	aminoacyl-tRNA hydrolase activity
FOA15_RS06070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOA15_RS06075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOA15_RS06080	COG2002	toxin-antitoxin pair type II binding
FOA15_RS06085	COG2244	polysaccharide biosynthetic process
FOA15_RS06090	COG3956	TIGRFAM MazG family protein
FOA15_RS06100	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOA15_RS06120	COG1098	S1 RNA binding domain
FOA15_RS06125	COG2208	phosphoserine phosphatase activity
FOA15_RS06130	COG2304	oxidoreductase activity
FOA15_RS06135	COG0515	serine threonine protein kinase
FOA15_RS06140	COG0037	tRNA processing
FOA15_RS06150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOA15_RS06160	COG0157	Belongs to the NadC ModD family
FOA15_RS06165	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FOA15_RS06180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOA15_RS06185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOA15_RS06190	COG0512	Glutamine amidotransferase of anthranilate synthase
FOA15_RS06195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOA15_RS06200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOA15_RS06205	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOA15_RS06210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOA15_RS06215	COG1396	sequence-specific DNA binding
FOA15_RS06220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOA15_RS06225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOA15_RS06235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOA15_RS06250	COG0318	PFAM AMP-dependent synthetase and ligase
FOA15_RS06255	COG1012	belongs to the aldehyde dehydrogenase family
FOA15_RS06260	COG0028	Belongs to the TPP enzyme family
FOA15_RS06265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOA15_RS06270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOA15_RS06300	COG0517	IMP dehydrogenase activity
FOA15_RS06300	COG0516	GMP reductase activity
FOA15_RS06305	COG1686	Belongs to the peptidase S11 family
FOA15_RS06350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOA15_RS06355	COG0590	tRNA wobble adenosine to inosine editing
FOA15_RS06360	COG5002	protein histidine kinase activity
FOA15_RS06365	COG1187	pseudouridine synthase activity
FOA15_RS06370	COG1360	Flagellar Motor Protein
FOA15_RS06375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOA15_RS06385	COG2154	pterin-4-alpha-carbinolamine dehydratase
FOA15_RS06395	COG0791	NLP P60 protein
FOA15_RS06420	COG2190	(PTS) system
FOA15_RS06425	COG1357	PFAM Pentapeptide repeats (8 copies)
FOA15_RS06445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOA15_RS06450	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOA15_RS06455	COG2211	Major facilitator Superfamily
FOA15_RS06460	COG1132	(ABC) transporter
FOA15_RS06470	COG0583	DNA-binding transcription factor activity
FOA15_RS06480	COG0018	arginyl-trna synthetase
FOA15_RS06490	COG0583	DNA-binding transcription factor activity
FOA15_RS06495	COG3842	ATPase activity
FOA15_RS06505	COG1178	ABC-type Fe3 transport system permease component
FOA15_RS06510	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOA15_RS06515	COG1404	Belongs to the peptidase S8 family
FOA15_RS06520	COG3343	RNA polymerase activity
FOA15_RS06525	COG0504	CTP synthase activity
FOA15_RS06530	COG2204	response regulator
FOA15_RS06540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOA15_RS06545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOA15_RS06555	COG0254	rRNA binding
FOA15_RS06565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOA15_RS06570	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOA15_RS06575	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOA15_RS06655	COG2508	Transcriptional regulator
FOA15_RS06660	COG3842	ATPase activity
FOA15_RS06665	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FOA15_RS06670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOA15_RS06675	COG0546	phosphoglycolate phosphatase activity
FOA15_RS06680	COG0110	maltose O-acetyltransferase activity
FOA15_RS06690	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FOA15_RS06695	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOA15_RS06700	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOA15_RS06705	COG0131	Imidazoleglycerol-phosphate dehydratase
FOA15_RS06710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOA15_RS06715	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOA15_RS06720	COG0107	imidazoleglycerol-phosphate synthase activity
FOA15_RS06725	COG0140	phosphoribosyl-ATP diphosphatase activity
FOA15_RS06725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOA15_RS06730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOA15_RS06745	COG1940	carbohydrate kinase activity
FOA15_RS06750	COG1660	Displays ATPase and GTPase activities
FOA15_RS06755	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOA15_RS06760	COG1481	regulation of sporulation
FOA15_RS06765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS06780	COG0740	serine-type endopeptidase activity
FOA15_RS06800	COG0126	phosphoglycerate kinase activity
FOA15_RS06805	COG0149	triose-phosphate isomerase activity
FOA15_RS06815	COG0148	phosphopyruvate hydratase activity
FOA15_RS06820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOA15_RS06825	COG0557	exoribonuclease II activity
FOA15_RS06830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOA15_RS06840	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOA15_RS06850	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOA15_RS06875	COG4224	UPF0291 protein
FOA15_RS06880	COG2259	Doxx family
FOA15_RS06885	COG0346	lactoylglutathione lyase activity
FOA15_RS06895	COG1695	Transcriptional regulator
FOA15_RS06900	COG1216	Glycosyl transferase, family 2
FOA15_RS06905	COG1842	Phage shock protein A
FOA15_RS06910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOA15_RS06915	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FOA15_RS06920	COG4260	virion core protein, lumpy skin disease virus
FOA15_RS06930	COG1175	transmembrane transport
FOA15_RS06945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOA15_RS06950	COG2076	Multidrug Resistance protein
FOA15_RS06965	COG3654	unkown
FOA15_RS06995	COG0534	Mate efflux family protein
FOA15_RS07010	COG4977	sequence-specific DNA binding
FOA15_RS07010	COG1917	Cupin 2, conserved barrel domain protein
FOA15_RS07015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS07015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS07015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOA15_RS07020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOA15_RS07025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOA15_RS07030	COG0383	alpha-mannosidase activity
FOA15_RS07035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS07035	COG3711	transcriptional antiterminator
FOA15_RS07050	COG3250	beta-galactosidase activity
FOA15_RS07070	COG0640	Transcriptional regulator
FOA15_RS07095	COG0789	Transcriptional regulator
FOA15_RS07095	COG4978	Transcriptional regulator
FOA15_RS07105	COG0596	Alpha beta hydrolase
FOA15_RS07110	COG2814	Major facilitator Superfamily
FOA15_RS07115	COG1309	transcriptional regulator
FOA15_RS07120	COG2814	Major facilitator Superfamily
FOA15_RS07125	COG2972	Histidine kinase
FOA15_RS07130	COG2207	Transcriptional regulator
FOA15_RS07130	COG4753	response regulator
FOA15_RS07135	COG2271	Major facilitator Superfamily
FOA15_RS07140	COG0800	Aldolase
FOA15_RS07150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOA15_RS07155	COG0572	uridine kinase
FOA15_RS07160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOA15_RS07165	COG2843	Capsule synthesis protein
FOA15_RS07170	COG0765	amino acid transport
FOA15_RS07175	COG1126	abc transporter atp-binding protein
FOA15_RS07195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOA15_RS07200	COG4715	Zinc finger, swim domain protein
FOA15_RS07215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOA15_RS07220	COG1554	hydrolase, family 65, central catalytic
FOA15_RS07225	COG1609	Transcriptional regulator
FOA15_RS07230	COG2190	(PTS) system
FOA15_RS07230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS07230	COG1263	PTS System
FOA15_RS07255	COG1846	Transcriptional regulator
FOA15_RS07260	COG0784	Response regulator, receiver
FOA15_RS07265	COG4191	Histidine kinase
FOA15_RS07290	COG0601	transmembrane transport
FOA15_RS07295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOA15_RS07300	COG0444	Belongs to the ABC transporter superfamily
FOA15_RS07305	COG4608	Belongs to the ABC transporter superfamily
FOA15_RS07320	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOA15_RS07335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOA15_RS07335	COG0574	Belongs to the PEP-utilizing enzyme family
FOA15_RS07340	COG1653	transport
FOA15_RS07350	COG1657	PFAM Prenyltransferase squalene oxidase
FOA15_RS07355	COG1917	Cupin 2, conserved barrel domain protein
FOA15_RS07355	COG2207	Transcriptional regulator
FOA15_RS07360	COG0673	inositol 2-dehydrogenase activity
FOA15_RS07375	COG1733	regulation of RNA biosynthetic process
FOA15_RS07380	COG2814	Major facilitator Superfamily
FOA15_RS07385	COG0656	L-ascorbic acid biosynthetic process
FOA15_RS07390	COG1609	Transcriptional regulator
FOA15_RS07395	COG1621	beta-fructofuranosidase activity
FOA15_RS07435	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOA15_RS07445	COG0697	spore germination
FOA15_RS07460	COG3507	Belongs to the glycosyl hydrolase 43 family
FOA15_RS07465	COG1278	Cold shock
FOA15_RS07480	COG1725	Transcriptional regulator
FOA15_RS07485	COG1131	(ABC) transporter
FOA15_RS07500	COG0583	DNA-binding transcription factor activity
FOA15_RS07515	COG1609	Transcriptional regulator
FOA15_RS07520	COG3459	Glycosyltransferase 36 associated
FOA15_RS07530	COG1653	transport
FOA15_RS07535	COG1175	transmembrane transport
FOA15_RS07540	COG0395	ABC-type sugar transport system, permease component
FOA15_RS07550	COG3119	arylsulfatase activity
FOA15_RS07560	COG1132	(ABC) transporter
FOA15_RS07575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOA15_RS07605	COG0584	glycerophosphoryl diester phosphodiesterase
FOA15_RS07615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOA15_RS07625	COG0463	Glycosyl transferase, family 2
FOA15_RS07630	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOA15_RS07635	COG0745	RESPONSE REGULATOR receiver
FOA15_RS07640	COG2205	protein histidine kinase activity
FOA15_RS07645	COG1404	Belongs to the peptidase S8 family
FOA15_RS07650	COG1227	inorganic diphosphatase activity
FOA15_RS07655	COG1846	Transcriptional regulator
FOA15_RS07660	COG1793	dna ligase
FOA15_RS07670	COG2322	membrane
FOA15_RS07685	COG0395	ABC-type sugar transport system, permease component
FOA15_RS07690	COG3291	Pkd domain containing protein
FOA15_RS07690	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOA15_RS07700	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FOA15_RS07705	COG1737	Transcriptional regulator
FOA15_RS07710	COG1940	carbohydrate kinase activity
FOA15_RS07715	COG1233	COG1233 Phytoene dehydrogenase and related
FOA15_RS07845	COG2197	response regulator
FOA15_RS07855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOA15_RS07890	COG4753	response regulator
FOA15_RS07890	COG2207	Transcriptional regulator
FOA15_RS07895	COG0583	DNA-binding transcription factor activity
FOA15_RS07900	COG0163	prenyltransferase activity
FOA15_RS07905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOA15_RS07925	COG4932	domain protein
FOA15_RS07925	COG5492	domain, Protein
FOA15_RS07930	COG1760	l-serine dehydratase
FOA15_RS07935	COG1760	l-serine dehydratase
FOA15_RS07945	COG0765	amino acid transport
FOA15_RS07950	COG0765	amino acid transport
FOA15_RS07955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOA15_RS07980	COG1388	LysM domain
FOA15_RS07980	COG4932	domain protein
FOA15_RS07990	COG1917	Cupin 2, conserved barrel domain protein
FOA15_RS07990	COG2207	Transcriptional regulator
FOA15_RS07995	COG2733	membrane
FOA15_RS08000	COG0745	RESPONSE REGULATOR receiver
FOA15_RS08000	COG2972	Histidine kinase
FOA15_RS08005	COG3279	Response regulator of the LytR AlgR family
FOA15_RS08010	COG0778	Nitroreductase
FOA15_RS08015	COG1733	regulation of RNA biosynthetic process
FOA15_RS08025	COG4549	nuclear export factor GLE1
FOA15_RS08030	COG1276	copper resistance
FOA15_RS08030	COG2372	response to copper ion
FOA15_RS08035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOA15_RS08035	COG2199	diguanylate cyclase activity
FOA15_RS08045	COG2814	Major facilitator Superfamily
FOA15_RS08055	COG2608	mercury ion transmembrane transporter activity
FOA15_RS08060	COG2217	Heavy metal translocating P-type atpase
FOA15_RS08065	COG0778	Nitroreductase
FOA15_RS08070	COG0084	hydrolase, TatD family'
FOA15_RS08075	COG1116	anion transmembrane transporter activity
FOA15_RS08080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOA15_RS08090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOA15_RS08095	COG0737	Belongs to the 5'-nucleotidase family
FOA15_RS08110	COG0366	Alpha amylase catalytic
FOA15_RS08120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOA15_RS08125	COG2011	ABC-type metal ion transport system permease component
FOA15_RS08140	COG0745	RESPONSE REGULATOR receiver
FOA15_RS08145	COG2205	protein histidine kinase activity
FOA15_RS08175	COG0515	serine threonine protein kinase
FOA15_RS08185	COG1070	Carbohydrate kinase
FOA15_RS08200	COG0024	Methionine aminopeptidase
FOA15_RS08205	COG4846	Membrane protein involved in cytochrome C biogenesis
FOA15_RS08215	COG0778	Nitroreductase
FOA15_RS08220	COG0392	lysyltransferase activity
FOA15_RS08220	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOA15_RS08230	COG2814	Major facilitator Superfamily
FOA15_RS08235	COG4106	trans-aconitate 2-methyltransferase activity
FOA15_RS08240	COG0596	Alpha beta hydrolase
FOA15_RS08245	COG0156	8-amino-7-oxononanoate synthase activity
FOA15_RS08255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOA15_RS08280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOA15_RS08280	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOA15_RS08290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOA15_RS08295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOA15_RS08310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOA15_RS08315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOA15_RS08320	COG0011	TIGRFAM Protein of
FOA15_RS08345	COG3209	COG3209 Rhs family protein
FOA15_RS08355	COG0463	Glycosyl transferase, family 2
FOA15_RS08355	COG1216	Glycosyl transferase, family 2
FOA15_RS08375	COG0412	Dienelactone hydrolase
FOA15_RS08380	COG2204	response regulator
FOA15_RS08385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOA15_RS08390	COG1454	alcohol dehydrogenase
FOA15_RS08400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOA15_RS08415	COG2731	YhcH YjgK YiaL family protein
FOA15_RS08420	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS08425	COG0640	Transcriptional regulator
FOA15_RS08430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOA15_RS08440	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOA15_RS08460	COG2770	Histidine kinase
FOA15_RS08460	COG3437	response regulator, receiver
FOA15_RS08470	COG0702	epimerase
FOA15_RS08475	COG0251	oxidation-reduction process
FOA15_RS08485	COG0385	Bile acid
FOA15_RS08490	COG1902	pentaerythritol trinitrate reductase activity
FOA15_RS08495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOA15_RS08500	COG2207	Transcriptional regulator
FOA15_RS08500	COG4753	response regulator
FOA15_RS08505	COG2972	Histidine kinase
FOA15_RS08525	COG2207	Transcriptional regulator
FOA15_RS08535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOA15_RS08550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOA15_RS08560	COG1876	peptidase activity
FOA15_RS08575	COG0754	glutathionylspermidine amidase activity
FOA15_RS08580	COG3766	membrane
FOA15_RS08590	COG2814	Major facilitator Superfamily
FOA15_RS08595	COG1846	Transcriptional regulator
FOA15_RS08605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOA15_RS08610	COG2357	RelA SpoT domain protein
FOA15_RS08615	COG1854	S-ribosylhomocysteine lyase activity
FOA15_RS08625	COG1464	Belongs to the NlpA lipoprotein family
FOA15_RS08645	COG1904	glucuronate isomerase
FOA15_RS08650	COG3250	beta-galactosidase activity
FOA15_RS08655	COG2211	Major facilitator Superfamily
FOA15_RS08680	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS08685	COG1312	Catalyzes the dehydration of D-mannonate
FOA15_RS08690	COG1802	Transcriptional regulator
FOA15_RS08695	COG0210	DNA helicase
FOA15_RS08725	COG1970	mechanosensitive ion channel activity
FOA15_RS08730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOA15_RS08735	COG1595	DNA-templated transcription, initiation
FOA15_RS08765	COG0024	Methionine aminopeptidase
FOA15_RS08775	COG1247	-acetyltransferase
FOA15_RS08805	COG4152	abc transporter atp-binding protein
FOA15_RS08810	COG1668	transmembrane transport
FOA15_RS08830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOA15_RS08835	COG2315	Protein conserved in bacteria
FOA15_RS08840	COG2030	dehydratase
FOA15_RS08845	COG1113	amino acid transport
FOA15_RS08850	COG0385	Bile acid
FOA15_RS08855	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOA15_RS08860	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOA15_RS08860	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOA15_RS08865	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS08865	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS08870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS08870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS08875	COG3715	PTS system
FOA15_RS08880	COG3716	PTS system mannose fructose sorbose family IID component
FOA15_RS08890	COG3250	beta-galactosidase activity
FOA15_RS08905	COG0366	Alpha amylase catalytic
FOA15_RS08910	COG1263	PTS System
FOA15_RS08910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS08915	COG2188	Transcriptional regulator
FOA15_RS08935	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOA15_RS08940	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS08945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOA15_RS08950	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOA15_RS08955	COG3711	transcriptional antiterminator
FOA15_RS08955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS08965	COG0531	amino acid
FOA15_RS08970	COG0697	spore germination
FOA15_RS08980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOA15_RS08985	COG0698	ribose 5-phosphate isomerase
FOA15_RS09000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOA15_RS09005	COG2146	nitrite reductase [NAD(P)H] activity
FOA15_RS09025	COG0697	spore germination
FOA15_RS09030	COG0531	amino acid
FOA15_RS09040	COG1695	Transcriptional regulator
FOA15_RS09045	COG3479	Phenolic acid decarboxylase
FOA15_RS09055	COG1733	regulation of RNA biosynthetic process
FOA15_RS09065	COG0745	RESPONSE REGULATOR receiver
FOA15_RS09070	COG5002	protein histidine kinase activity
FOA15_RS09075	COG1183	phosphatidylcholine synthase activity
FOA15_RS09080	COG0586	Pfam SNARE associated Golgi protein
FOA15_RS09085	COG3223	Belongs to the PsiE family
FOA15_RS09090	COG0628	permease
FOA15_RS09105	COG1309	transcriptional regulator
FOA15_RS09110	COG2315	Protein conserved in bacteria
FOA15_RS09115	COG0778	Nitroreductase
FOA15_RS09120	COG0346	lactoylglutathione lyase activity
FOA15_RS09145	COG2211	Major facilitator Superfamily
FOA15_RS09155	COG2972	Histidine kinase
FOA15_RS09160	COG2207	Transcriptional regulator
FOA15_RS09160	COG4753	response regulator
FOA15_RS09205	COG2323	membrane
FOA15_RS09230	COG0789	Transcriptional regulator
FOA15_RS09235	COG2814	Major facilitator Superfamily
FOA15_RS09240	COG1012	belongs to the aldehyde dehydrogenase family
FOA15_RS09245	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOA15_RS09250	COG2002	toxin-antitoxin pair type II binding
FOA15_RS09260	COG1956	GAF domain-containing protein
FOA15_RS09265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOA15_RS09275	COG4721	ABC-type cobalt transport system, permease component
FOA15_RS09280	COG1122	ATPase activity
FOA15_RS09285	COG0477	Major facilitator Superfamily
FOA15_RS09290	COG1609	Transcriptional regulator
FOA15_RS09305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOA15_RS09310	COG0366	Alpha amylase catalytic
FOA15_RS09335	COG1846	Transcriptional regulator
FOA15_RS09350	COG1621	beta-fructofuranosidase activity
FOA15_RS09355	COG1621	beta-fructofuranosidase activity
FOA15_RS09360	COG1846	Transcriptional regulator
FOA15_RS09375	COG2081	HI0933 family
FOA15_RS09380	COG5002	protein histidine kinase activity
FOA15_RS09390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOA15_RS09420	COG1454	alcohol dehydrogenase
FOA15_RS09425	COG2207	Transcriptional regulator
FOA15_RS09425	COG1917	Cupin 2, conserved barrel domain protein
FOA15_RS09430	COG2318	DinB family
FOA15_RS09440	COG0456	acetyltransferase
FOA15_RS09450	COG0328	RNA-DNA hybrid ribonuclease activity
FOA15_RS09455	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOA15_RS09465	COG0302	gtp cyclohydrolase
FOA15_RS09470	COG0095	Lipoate-protein ligase
FOA15_RS09475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOA15_RS09485	COG1414	Transcriptional regulator
FOA15_RS09490	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOA15_RS09500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOA15_RS09505	COG0436	Aminotransferase
FOA15_RS09510	COG0371	Dehydrogenase
FOA15_RS09520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOA15_RS09525	COG0765	amino acid transport
FOA15_RS09530	COG1126	abc transporter atp-binding protein
FOA15_RS09535	COG1473	amidohydrolase
FOA15_RS09540	COG2079	MmgE PrpD family protein
FOA15_RS09550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOA15_RS09580	COG2972	Histidine kinase
FOA15_RS09585	COG4753	response regulator
FOA15_RS09585	COG2207	Transcriptional regulator
FOA15_RS09590	COG1653	transport
FOA15_RS09595	COG1175	transmembrane transport
FOA15_RS09600	COG0395	ABC-type sugar transport system, permease component
FOA15_RS09605	COG2755	lipolytic protein G-D-S-L family
FOA15_RS09610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOA15_RS09620	COG0697	spore germination
FOA15_RS09625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOA15_RS09630	COG1316	TRANSCRIPTIONal
FOA15_RS09635	COG4555	ABC transporter
FOA15_RS09650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOA15_RS09655	COG0586	Pfam SNARE associated Golgi protein
FOA15_RS09660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOA15_RS09660	COG0519	Catalyzes the synthesis of GMP from XMP
FOA15_RS09665	COG0673	inositol 2-dehydrogenase activity
FOA15_RS09710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOA15_RS09725	COG0252	asparaginase activity
FOA15_RS09735	COG3326	Membrane
FOA15_RS09740	COG0589	response to stress
FOA15_RS09745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOA15_RS09750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOA15_RS09755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOA15_RS09765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOA15_RS09770	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOA15_RS09775	COG0047	phosphoribosylformylglycinamidine synthase activity
FOA15_RS09780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOA15_RS09785	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOA15_RS09795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOA15_RS09800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOA15_RS09810	COG0151	Belongs to the GarS family
FOA15_RS09815	COG1309	transcriptional regulator
FOA15_RS09830	COG1126	abc transporter atp-binding protein
FOA15_RS09840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS09845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS09850	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOA15_RS09860	COG3290	protein histidine kinase activity
FOA15_RS09870	COG0656	L-ascorbic acid biosynthetic process
FOA15_RS09880	COG0640	Transcriptional regulator
FOA15_RS09885	COG0400	carboxylic ester hydrolase activity
FOA15_RS09895	COG1653	transport
FOA15_RS09900	COG1175	transmembrane transport
FOA15_RS09905	COG0395	ABC-type sugar transport system, permease component
FOA15_RS09910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOA15_RS09915	COG3507	Belongs to the glycosyl hydrolase 43 family
FOA15_RS09920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS09925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS09950	COG3384	dioxygenase
FOA15_RS09965	COG1470	cell adhesion involved in biofilm formation
FOA15_RS09970	COG1392	Phosphate transport regulator
FOA15_RS09975	COG0306	phosphate transporter
FOA15_RS09980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOA15_RS09995	COG0598	Magnesium transport protein CorA
FOA15_RS10005	COG4496	protein, YerC YecD
FOA15_RS10015	COG1597	lipid kinase activity
FOA15_RS10075	COG2207	Transcriptional regulator
FOA15_RS10075	COG3708	Transcriptional regulator
FOA15_RS10110	COG1846	Transcriptional regulator
FOA15_RS10120	COG0702	epimerase
FOA15_RS10175	COG0778	Nitroreductase
FOA15_RS10180	COG0583	DNA-binding transcription factor activity
FOA15_RS10195	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOA15_RS10240	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS10245	COG1113	amino acid transport
FOA15_RS10265	COG0778	Nitroreductase
FOA15_RS10270	COG1733	regulation of RNA biosynthetic process
FOA15_RS10275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOA15_RS10290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOA15_RS10295	COG3239	Fatty acid desaturase
FOA15_RS10300	COG4585	Histidine kinase
FOA15_RS10305	COG2197	response regulator
FOA15_RS10310	COG1428	Deoxynucleoside kinase
FOA15_RS10315	COG1428	Deoxynucleoside kinase
FOA15_RS10325	COG0673	inositol 2-dehydrogenase activity
FOA15_RS10340	COG2814	Major facilitator Superfamily
FOA15_RS10345	COG0583	DNA-binding transcription factor activity
FOA15_RS10350	COG2814	Major facilitator Superfamily
FOA15_RS10355	COG0710	3-dehydroquinate dehydratase activity
FOA15_RS10360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOA15_RS10380	COG2814	Major facilitator Superfamily
FOA15_RS10385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOA15_RS10390	COG4989	oxidoreductase activity
FOA15_RS10410	COG3541	Predicted nucleotidyltransferase
FOA15_RS10425	COG1122	ATPase activity
FOA15_RS10435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOA15_RS10440	COG2011	ABC-type metal ion transport system permease component
FOA15_RS10460	COG0673	inositol 2-dehydrogenase activity
FOA15_RS10465	COG1472	Belongs to the glycosyl hydrolase 3 family
FOA15_RS10485	COG5002	protein histidine kinase activity
FOA15_RS10500	COG4474	Belongs to the UPF0398 family
FOA15_RS10505	COG3401	FG-GAP repeat protein
FOA15_RS10525	COG2116	formate transmembrane transporter activity
FOA15_RS10530	COG0561	phosphatase activity
FOA15_RS10555	COG2310	stress, protein
FOA15_RS10560	COG2310	stress, protein
FOA15_RS10565	COG2310	stress, protein
FOA15_RS10575	COG0861	Integral membrane protein TerC family
FOA15_RS10590	COG1358	cellular component organization or biogenesis
FOA15_RS10620	COG3177	Filamentation induced by cAMP protein fic
FOA15_RS10630	COG4166	transmembrane transport
FOA15_RS10635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOA15_RS10640	COG0601	transmembrane transport
FOA15_RS10645	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOA15_RS10650	COG0765	amino acid transport
FOA15_RS10655	COG1126	abc transporter atp-binding protein
FOA15_RS10660	COG0024	Methionine aminopeptidase
FOA15_RS10670	COG1396	sequence-specific DNA binding
FOA15_RS10680	COG2030	dehydratase
FOA15_RS10690	COG2315	Protein conserved in bacteria
FOA15_RS10705	COG1486	melibiose metabolic process
FOA15_RS10710	COG2972	Histidine kinase
FOA15_RS10715	COG2207	Transcriptional regulator
FOA15_RS10725	COG1175	transmembrane transport
FOA15_RS10730	COG0395	ABC-type sugar transport system, permease component
FOA15_RS10735	COG0006	proline dipeptidase activity
FOA15_RS10750	COG3938	Belongs to the proline racemase family
FOA15_RS10755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOA15_RS10760	COG1012	belongs to the aldehyde dehydrogenase family
FOA15_RS10790	COG0583	DNA-binding transcription factor activity
FOA15_RS10795	COG1473	amidohydrolase
FOA15_RS10800	COG1288	antiporter activity
FOA15_RS10805	COG3835	regulator
FOA15_RS10810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOA15_RS10815	COG2271	Major facilitator Superfamily
FOA15_RS10820	COG3257	ureidoglycine aminohydrolase activity
FOA15_RS10825	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOA15_RS10830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOA15_RS10835	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOA15_RS10845	COG0549	Belongs to the carbamate kinase family
FOA15_RS10850	COG3401	FG-GAP repeat protein
FOA15_RS10860	COG4209	transmembrane transport
FOA15_RS10865	COG0395	ABC-type sugar transport system, permease component
FOA15_RS10875	COG1621	beta-fructofuranosidase activity
FOA15_RS10890	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FOA15_RS10905	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FOA15_RS10910	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FOA15_RS10925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOA15_RS10930	COG1132	(ABC) transporter
FOA15_RS10935	COG1132	(ABC) transporter
FOA15_RS10940	COG1301	dicarboxylic acid transport
FOA15_RS10945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOA15_RS10950	COG3290	protein histidine kinase activity
FOA15_RS11030	COG2814	Major facilitator Superfamily
FOA15_RS11035	COG2207	Transcriptional regulator
FOA15_RS11035	COG4753	response regulator
FOA15_RS11040	COG2972	Histidine kinase
FOA15_RS11050	COG1486	melibiose metabolic process
FOA15_RS11055	COG5297	Belongs to the glycosyl hydrolase family 6
FOA15_RS11065	COG4999	Histidine kinase
FOA15_RS11065	COG3850	Histidine kinase
FOA15_RS11065	COG3437	response regulator, receiver
FOA15_RS11065	COG2205	protein histidine kinase activity
FOA15_RS11070	COG1725	Transcriptional regulator
FOA15_RS11075	COG1131	(ABC) transporter
FOA15_RS11105	COG0656	L-ascorbic acid biosynthetic process
FOA15_RS11110	COG3663	DNA glycosylase
FOA15_RS11115	COG0686	Belongs to the AlaDH PNT family
FOA15_RS11145	COG0840	transmembrane signaling receptor activity
FOA15_RS11155	COG5522	Integral membrane protein (intg_mem_TP0381)
FOA15_RS11165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOA15_RS11190	COG1605	Chorismate mutase
FOA15_RS11190	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOA15_RS11200	COG2205	protein histidine kinase activity
FOA15_RS11245	COG2002	toxin-antitoxin pair type II binding
FOA15_RS11275	COG4753	response regulator
FOA15_RS11275	COG2207	Transcriptional regulator
FOA15_RS11280	COG1151	hydroxylamine reductase activity
FOA15_RS11300	COG4213	ABC transporter substrate-binding protein
FOA15_RS11310	COG4214	carbohydrate transport
FOA15_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS11325	COG1522	sequence-specific DNA binding
FOA15_RS11335	COG2217	Heavy metal translocating P-type atpase
FOA15_RS11340	COG2223	nitrite transmembrane transporter activity
FOA15_RS11365	COG1621	beta-fructofuranosidase activity
FOA15_RS11370	COG4977	sequence-specific DNA binding
FOA15_RS11370	COG1917	Cupin 2, conserved barrel domain protein
FOA15_RS11375	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOA15_RS11385	COG0720	synthase
FOA15_RS11390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOA15_RS11420	COG0737	Belongs to the 5'-nucleotidase family
FOA15_RS11430	COG1396	sequence-specific DNA binding
FOA15_RS11450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOA15_RS11490	COG2823	Periplasmic or secreted lipoprotein
FOA15_RS11490	COG1652	LysM domain
FOA15_RS11510	COG3299	homolog of phage Mu protein gp47
FOA15_RS11555	COG4824	toxin secretion phage lysis holin
FOA15_RS11560	COG3757	hydrolase, family 25
FOA15_RS11565	COG0747	negative chemotaxis
FOA15_RS11580	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOA15_RS11585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOA15_RS11600	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOA15_RS11605	COG3773	Cell wall hydrolase
FOA15_RS11610	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOA15_RS11615	COG0067	glutamate synthase
FOA15_RS11615	COG0070	glutamate synthase
FOA15_RS11615	COG0069	glutamate synthase activity
FOA15_RS11625	COG2197	response regulator
FOA15_RS11630	COG3944	biosynthesis protein
FOA15_RS11635	COG0489	protein tyrosine kinase activity
FOA15_RS11640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOA15_RS11645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOA15_RS11650	COG1216	Glycosyl transferase, family 2
FOA15_RS11660	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FOA15_RS11680	COG0438	transferase activity, transferring glycosyl groups
FOA15_RS11685	COG0438	transferase activity, transferring glycosyl groups
FOA15_RS11695	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOA15_RS11705	COG0662	Cupin 2, conserved barrel domain protein
FOA15_RS11705	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOA15_RS11710	COG2133	pyrroloquinoline quinone binding
FOA15_RS11710	COG5183	chlorophyll binding
FOA15_RS11720	COG1396	sequence-specific DNA binding
FOA15_RS11725	COG3944	biosynthesis protein
FOA15_RS11730	COG0489	protein tyrosine kinase activity
FOA15_RS11735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOA15_RS11740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOA15_RS11770	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FOA15_RS11775	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOA15_RS11780	COG1316	TRANSCRIPTIONal
FOA15_RS11790	COG1131	(ABC) transporter
FOA15_RS11795	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOA15_RS11805	COG0739	heme binding
FOA15_RS11815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOA15_RS11825	COG0367	asparagine synthase
FOA15_RS11855	COG1132	(ABC) transporter
FOA15_RS11860	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FOA15_RS11895	COG2972	Histidine kinase
FOA15_RS11895	COG0745	RESPONSE REGULATOR receiver
FOA15_RS11900	COG3279	Response regulator of the LytR AlgR family
FOA15_RS11905	COG1361	Conserved repeat domain
FOA15_RS11905	COG2911	Protein conserved in bacteria
FOA15_RS11905	COG3266	domain, Protein
FOA15_RS11915	COG0802	atpase or kinase
FOA15_RS11920	COG1214	PFAM Peptidase M22, glycoprotease
FOA15_RS11925	COG0456	acetyltransferase
FOA15_RS11930	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOA15_RS11935	COG0488	(ABC) transporter
FOA15_RS11940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOA15_RS11945	COG0315	cyclic pyranopterin monophosphate synthase activity
FOA15_RS11950	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOA15_RS11955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOA15_RS11960	COG0805	protein transport
FOA15_RS11965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOA15_RS11970	COG0459	protein refolding
FOA15_RS12020	COG2244	polysaccharide biosynthetic process
FOA15_RS12055	COG0395	ABC-type sugar transport system, permease component
FOA15_RS12060	COG1653	transport
FOA15_RS12065	COG1309	transcriptional regulator
FOA15_RS12070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOA15_RS12080	COG2113	Glycine betaine
FOA15_RS12085	COG4175	Glycine betaine
FOA15_RS12085	COG0517	IMP dehydrogenase activity
FOA15_RS12090	COG1510	regulation of RNA biosynthetic process
FOA15_RS12095	COG2272	Belongs to the type-B carboxylesterase lipase family
FOA15_RS12115	COG1131	(ABC) transporter
FOA15_RS12120	COG2205	protein histidine kinase activity
FOA15_RS12125	COG0745	RESPONSE REGULATOR receiver
FOA15_RS12140	COG4185	zeta toxin
FOA15_RS12180	COG1518	maintenance of DNA repeat elements
FOA15_RS12185	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FOA15_RS12190	COG3631	Ketosteroid isomerase-related protein
FOA15_RS12195	COG1309	transcriptional regulator
FOA15_RS12205	COG0667	Aldo Keto reductase
FOA15_RS12210	COG0789	Transcriptional regulator
FOA15_RS12215	COG3293	Transposase
FOA15_RS12230	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOA15_RS12235	COG0662	Cupin 2, conserved barrel domain protein
FOA15_RS12235	COG2207	Transcriptional regulator
FOA15_RS12245	COG1280	lysine exporter protein (LysE YggA)
FOA15_RS12250	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOA15_RS12255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOA15_RS12260	COG0864	Transcriptional regulator
FOA15_RS12265	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOA15_RS12270	COG2183	response to ionizing radiation
FOA15_RS12295	COG0561	phosphatase activity
FOA15_RS12300	COG1349	DNA-binding transcription factor activity
FOA15_RS12340	COG0830	nickel cation binding
FOA15_RS12350	COG0386	Belongs to the glutathione peroxidase family
FOA15_RS12365	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FOA15_RS12380	COG1914	H( )-stimulated, divalent metal cation uptake system
FOA15_RS12390	COG3011	Protein conserved in bacteria
FOA15_RS12400	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOA15_RS12405	COG1121	(ABC) transporter
FOA15_RS12410	COG1321	iron dependent repressor
FOA15_RS12410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOA15_RS12415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOA15_RS12420	COG2205	protein histidine kinase activity
FOA15_RS12465	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOA15_RS12480	COG0778	Nitroreductase
FOA15_RS12500	COG1090	epimerase
FOA15_RS12505	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOA15_RS12510	COG0788	formyltetrahydrofolate deformylase activity
FOA15_RS12530	COG0166	Belongs to the GPI family
FOA15_RS12535	COG1739	Uncharacterized protein family UPF0029
FOA15_RS12545	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOA15_RS12550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOA15_RS12550	COG0321	lipoyl(octanoyl) transferase activity
FOA15_RS12555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOA15_RS12565	COG0561	phosphatase activity
FOA15_RS12570	COG0095	Lipoate-protein ligase
FOA15_RS12575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOA15_RS12580	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FOA15_RS12585	COG0588	phosphoglycerate mutase activity
FOA15_RS12590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOA15_RS12595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS12600	COG1120	ATPase activity
FOA15_RS12605	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FOA15_RS12615	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FOA15_RS12620	COG1492	cobalamin metabolic process
FOA15_RS12625	COG0840	transmembrane signaling receptor activity
FOA15_RS12630	COG1263	PTS System
FOA15_RS12630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS12630	COG2190	(PTS) system
FOA15_RS12635	COG3711	transcriptional antiterminator
FOA15_RS12640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS12640	COG1263	PTS System
FOA15_RS12640	COG2190	(PTS) system
FOA15_RS12650	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOA15_RS12690	COG1388	LysM domain
FOA15_RS12690	COG3584	3D domain protein
FOA15_RS12790	COG0006	proline dipeptidase activity
FOA15_RS12800	COG1247	-acetyltransferase
FOA15_RS12805	COG3610	response to peptide
FOA15_RS12810	COG2966	Psort location CytoplasmicMembrane, score
FOA15_RS12825	COG2112	serine threonine protein kinase
FOA15_RS12835	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOA15_RS12850	COG0514	ATP-dependent DNA helicase (RecQ)
FOA15_RS12860	COG1785	Belongs to the alkaline phosphatase family
FOA15_RS12875	COG0586	Pfam SNARE associated Golgi protein
FOA15_RS12905	COG1051	belongs to the nudix hydrolase family
FOA15_RS12905	COG1056	cytidyltransferase-related domain
FOA15_RS12930	COG1418	mRNA catabolic process
FOA15_RS12935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOA15_RS12940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS12945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS12950	COG2819	hydrolase of the alpha beta superfamily
FOA15_RS12955	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS12960	COG1169	isochorismate synthase
FOA15_RS12965	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOA15_RS12970	COG3433	isochorismatase activity
FOA15_RS12970	COG1535	isochorismatase
FOA15_RS12975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOA15_RS12980	COG3251	PFAM MbtH domain protein
FOA15_RS13025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOA15_RS13030	COG2205	protein histidine kinase activity
FOA15_RS13035	COG2755	lipolytic protein G-D-S-L family
FOA15_RS13130	COG2814	Major facilitator Superfamily
FOA15_RS13135	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS13140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS13140	COG1263	PTS System
FOA15_RS13140	COG2190	(PTS) system
FOA15_RS13145	COG3711	transcriptional antiterminator
FOA15_RS13150	COG0567	Dehydrogenase, E1 component
FOA15_RS13155	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOA15_RS13160	COG2318	DinB family
FOA15_RS13170	COG1482	cell wall glycoprotein biosynthetic process
FOA15_RS13175	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOA15_RS13180	COG1242	4 iron, 4 sulfur cluster binding
FOA15_RS13190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOA15_RS13195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOA15_RS13200	COG0671	phosphoesterase, PA-phosphatase related
FOA15_RS13205	COG1215	transferase activity, transferring glycosyl groups
FOA15_RS13215	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOA15_RS13220	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOA15_RS13255	COG0028	Belongs to the TPP enzyme family
FOA15_RS13260	COG0440	acetolactate synthase activity
FOA15_RS13265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOA15_RS13270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOA15_RS13280	COG0450	alkyl hydroperoxide reductase
FOA15_RS13290	COG4191	Histidine kinase
FOA15_RS13315	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOA15_RS13325	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FOA15_RS13335	COG1193	negative regulation of DNA recombination
FOA15_RS13340	COG3766	membrane
FOA15_RS13350	COG0477	Major facilitator Superfamily
FOA15_RS13370	COG1522	sequence-specific DNA binding
FOA15_RS13375	COG0436	Aminotransferase
FOA15_RS13390	COG2096	Adenosyltransferase
FOA15_RS13395	COG0564	pseudouridine synthase activity
FOA15_RS13400	COG1393	Belongs to the ArsC family
FOA15_RS13405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOA15_RS13410	COG1940	carbohydrate kinase activity
FOA15_RS13420	COG0598	Magnesium transport protein CorA
FOA15_RS13425	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOA15_RS13430	COG0626	cystathionine gamma-synthase activity
FOA15_RS13435	COG0626	cystathionine gamma-synthase activity
FOA15_RS13440	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FOA15_RS13455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOA15_RS13460	COG0475	glutathione-regulated potassium exporter activity
FOA15_RS13465	COG0490	domain, Protein
FOA15_RS13480	COG3584	3D domain protein
FOA15_RS13490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOA15_RS13495	COG0745	RESPONSE REGULATOR receiver
FOA15_RS13500	COG3850	Histidine kinase
FOA15_RS13500	COG5002	protein histidine kinase activity
FOA15_RS13505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOA15_RS13510	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOA15_RS13515	COG0174	glutamine synthetase
FOA15_RS13530	COG2002	toxin-antitoxin pair type II binding
FOA15_RS13545	COG2197	response regulator
FOA15_RS13560	COG2766	serine protein kinase
FOA15_RS13590	COG3212	peptidase
FOA15_RS13600	COG5002	protein histidine kinase activity
FOA15_RS13600	COG3850	Histidine kinase
FOA15_RS13605	COG0745	RESPONSE REGULATOR receiver
FOA15_RS13625	COG4126	flavin adenine dinucleotide binding
FOA15_RS13630	COG2309	aminopeptidase activity
FOA15_RS13640	COG2508	Transcriptional regulator
FOA15_RS13645	COG0745	RESPONSE REGULATOR receiver
FOA15_RS13650	COG5002	protein histidine kinase activity
FOA15_RS13660	COG2719	SpoVR family
FOA15_RS13665	COG2718	Belongs to the UPF0229 family
FOA15_RS13680	COG1396	sequence-specific DNA binding
FOA15_RS13685	COG1607	acyl-coa hydrolase
FOA15_RS13700	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOA15_RS13710	COG1307	EDD domain protein, DegV family
FOA15_RS13720	COG2363	Small membrane protein
FOA15_RS13730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOA15_RS13780	COG3377	Domain of unknown function (DUF1805)
FOA15_RS13790	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOA15_RS13795	COG0783	Belongs to the Dps family
FOA15_RS13800	COG0396	ATPase activity
FOA15_RS13805	COG0719	Fe-S assembly protein
FOA15_RS13810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOA15_RS13815	COG0822	iron-sulfur transferase activity
FOA15_RS13820	COG0719	Fe-S assembly protein
FOA15_RS13840	COG0737	Belongs to the 5'-nucleotidase family
FOA15_RS13850	COG0535	radical SAM domain protein
FOA15_RS13855	COG1253	flavin adenine dinucleotide binding
FOA15_RS13870	COG3546	catalase activity
FOA15_RS13875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOA15_RS13900	COG0189	ligase activity
FOA15_RS13905	COG0189	ligase activity
FOA15_RS13910	COG0189	ligase activity
FOA15_RS13915	COG0189	ligase activity
FOA15_RS13930	COG4109	DRTGG domain
FOA15_RS13950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOA15_RS13960	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOA15_RS13965	COG0825	malonyl-CoA metabolic process
FOA15_RS13970	COG0469	pyruvate kinase activity
FOA15_RS13975	COG0583	DNA-binding transcription factor activity
FOA15_RS13980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOA15_RS13985	COG0573	inorganic phosphate transmembrane transporter activity
FOA15_RS13990	COG0581	inorganic phosphate transmembrane transporter activity
FOA15_RS13995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOA15_RS14005	COG0824	Thioesterase
FOA15_RS14010	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOA15_RS14015	COG0628	permease
FOA15_RS14020	COG0372	Belongs to the citrate synthase family
FOA15_RS14025	COG0538	isocitrate dehydrogenase activity
FOA15_RS14030	COG0039	L-malate dehydrogenase activity
FOA15_RS14045	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS14050	COG5002	protein histidine kinase activity
FOA15_RS14055	COG0745	RESPONSE REGULATOR receiver
FOA15_RS14065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOA15_RS14070	COG0704	Plays a role in the regulation of phosphate uptake
FOA15_RS14075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOA15_RS14075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOA15_RS14080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOA15_RS14085	COG1971	Probably functions as a manganese efflux pump
FOA15_RS14090	COG0237	dephospho-CoA kinase activity
FOA15_RS14105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOA15_RS14120	COG1846	Transcriptional regulator
FOA15_RS14130	COG3254	rhamnose metabolic process
FOA15_RS14135	COG2972	Histidine kinase
FOA15_RS14140	COG4753	response regulator
FOA15_RS14140	COG2207	Transcriptional regulator
FOA15_RS14145	COG1653	transport
FOA15_RS14150	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOA15_RS14175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS14180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS14205	COG2223	nitrite transmembrane transporter activity
FOA15_RS14225	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOA15_RS14230	COG1140	nitrate reductase beta subunit
FOA15_RS14240	COG2181	nitrate reductase activity
FOA15_RS14260	COG1349	DNA-binding transcription factor activity
FOA15_RS14265	COG1105	Belongs to the carbohydrate kinase PfkB family
FOA15_RS14270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS14270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOA15_RS14270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOA15_RS14275	COG3711	transcriptional antiterminator
FOA15_RS14280	COG2190	(PTS) system
FOA15_RS14280	COG1263	PTS System
FOA15_RS14280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS14285	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS14290	COG0583	DNA-binding transcription factor activity
FOA15_RS14295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOA15_RS14310	COG0326	Molecular chaperone. Has ATPase activity
FOA15_RS14345	COG3250	beta-galactosidase activity
FOA15_RS14370	COG3279	Response regulator of the LytR AlgR family
FOA15_RS14375	COG2972	Histidine kinase
FOA15_RS14390	COG4209	transmembrane transport
FOA15_RS14395	COG0395	ABC-type sugar transport system, permease component
FOA15_RS14400	COG3507	Belongs to the glycosyl hydrolase 43 family
FOA15_RS14410	COG5520	Belongs to the glycosyl hydrolase 30 family
FOA15_RS14415	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOA15_RS14425	COG0371	Dehydrogenase
FOA15_RS14440	COG1069	ribulokinase activity
FOA15_RS14475	COG0726	polysaccharide deacetylase
FOA15_RS14480	COG4824	toxin secretion phage lysis holin
FOA15_RS14490	COG2445	Protein of unknown function DUF86
FOA15_RS14505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOA15_RS14525	COG4844	belongs to the
FOA15_RS14535	COG1368	sulfuric ester hydrolase activity
FOA15_RS14540	COG0116	Belongs to the methyltransferase superfamily
FOA15_RS14545	COG4122	O-methyltransferase activity
FOA15_RS14550	COG2814	Major facilitator Superfamily
FOA15_RS14555	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOA15_RS14570	COG2843	Capsule synthesis protein
FOA15_RS14575	COG0584	glycerophosphoryl diester phosphodiesterase
FOA15_RS14580	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOA15_RS14590	COG0488	(ABC) transporter
FOA15_RS14595	COG1363	Peptidase, m42
FOA15_RS14600	COG5416	Lipopolysaccharide assembly protein A domain
FOA15_RS14605	COG1164	Oligoendopeptidase f
FOA15_RS14620	COG0534	Mate efflux family protein
FOA15_RS14655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOA15_RS14660	COG0513	Belongs to the DEAD box helicase family
FOA15_RS14665	COG5578	integral membrane protein
FOA15_RS14680	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOA15_RS14685	COG0705	Rhomboid family
FOA15_RS14690	COG0583	DNA-binding transcription factor activity
FOA15_RS14695	COG2738	Putative neutral zinc metallopeptidase
FOA15_RS14700	COG0789	Transcriptional regulator
FOA15_RS14705	COG0004	ammonium transporteR
FOA15_RS14715	COG2176	DNA-directed DNA polymerase activity
FOA15_RS14720	COG3118	belongs to the thioredoxin family
FOA15_RS14725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOA15_RS14730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOA15_RS14735	COG1141	Ferredoxin
FOA15_RS14740	COG1376	ErfK ybiS ycfS ynhG family protein
FOA15_RS14750	COG0167	dihydroorotate dehydrogenase activity
FOA15_RS14755	COG2357	RelA SpoT domain protein
FOA15_RS14760	COG1547	Domain of unknown function (DUF309)
FOA15_RS14765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOA15_RS14770	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FOA15_RS14770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOA15_RS14775	COG1187	pseudouridine synthase activity
FOA15_RS14780	COG3447	MASE1 domain protein
FOA15_RS14780	COG5001	Diguanylate cyclase
FOA15_RS14780	COG5002	protein histidine kinase activity
FOA15_RS14790	COG3949	Membrane
FOA15_RS14795	COG0586	Pfam SNARE associated Golgi protein
FOA15_RS14800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOA15_RS14815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOA15_RS14830	COG0667	Aldo Keto reductase
FOA15_RS14835	COG1309	transcriptional regulator
FOA15_RS14840	COG0300	oxidoreductase activity
FOA15_RS14850	COG1902	pentaerythritol trinitrate reductase activity
FOA15_RS14865	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS14870	COG0183	Belongs to the thiolase family
FOA15_RS14875	COG4689	acetoacetate decarboxylase
FOA15_RS14910	COG0006	proline dipeptidase activity
FOA15_RS14915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOA15_RS14920	COG2861	carbohydrate metabolic process
FOA15_RS14945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOA15_RS14955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOA15_RS14965	COG2378	regulation of single-species biofilm formation
FOA15_RS14975	COG2814	Major facilitator Superfamily
FOA15_RS15005	COG0395	ABC-type sugar transport system, permease component
FOA15_RS15010	COG3507	Belongs to the glycosyl hydrolase 43 family
FOA15_RS15015	COG3940	Belongs to the glycosyl hydrolase 43 family
FOA15_RS15020	COG2226	methyltransferase
FOA15_RS15030	COG0456	acetyltransferase
FOA15_RS15035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOA15_RS15040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOA15_RS15045	COG1780	Probably involved in ribonucleotide reductase function
FOA15_RS15075	COG1609	Transcriptional regulator
FOA15_RS15095	COG2207	Transcriptional regulator
FOA15_RS15100	COG1940	carbohydrate kinase activity
FOA15_RS15110	COG1653	transport
FOA15_RS15115	COG4209	transmembrane transport
FOA15_RS15120	COG0395	ABC-type sugar transport system, permease component
FOA15_RS15140	COG4895	conserved protein (DUF2196)
FOA15_RS15145	COG3647	Membrane
FOA15_RS15150	COG0438	transferase activity, transferring glycosyl groups
FOA15_RS15160	COG4129	membrane
FOA15_RS15165	COG3973	AAA domain
FOA15_RS15170	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOA15_RS15175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOA15_RS15185	COG2207	Transcriptional regulator
FOA15_RS15185	COG1917	Cupin 2, conserved barrel domain protein
FOA15_RS15190	COG1501	Belongs to the glycosyl hydrolase 31 family
FOA15_RS15200	COG0840	transmembrane signaling receptor activity
FOA15_RS15200	COG5278	phosphoserine phosphatase activity
FOA15_RS15205	COG2814	Major facilitator Superfamily
FOA15_RS15210	COG2814	Major facilitator Superfamily
FOA15_RS15215	COG1846	Transcriptional regulator
FOA15_RS15220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOA15_RS15235	COG0726	polysaccharide deacetylase
FOA15_RS15235	COG1649	PFAM Uncharacterised BCR, COG1649
FOA15_RS15255	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOA15_RS15265	COG1846	Transcriptional regulator
FOA15_RS15270	COG2211	Major facilitator Superfamily
FOA15_RS15285	COG2755	lipolytic protein G-D-S-L family
FOA15_RS15290	COG1309	transcriptional regulator
FOA15_RS15310	COG0640	Transcriptional regulator
FOA15_RS15320	COG0346	lactoylglutathione lyase activity
FOA15_RS15325	COG0791	NLP P60 protein
FOA15_RS15330	COG1454	alcohol dehydrogenase
FOA15_RS15335	COG1846	Transcriptional regulator
FOA15_RS15340	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOA15_RS15350	COG3655	Transcriptional regulator
FOA15_RS15385	COG0531	amino acid
FOA15_RS15410	COG0742	ribosomal rna small subunit methyltransferase
FOA15_RS15415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOA15_RS15420	COG3314	Sporulation integral membrane protein YlbJ
FOA15_RS15425	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOA15_RS15430	COG1323	Belongs to the UPF0348 family
FOA15_RS15440	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOA15_RS15450	COG0416	fatty acid biosynthetic process
FOA15_RS15460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOA15_RS15470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOA15_RS15475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOA15_RS15480	COG0571	ribonuclease III activity
FOA15_RS15485	COG1196	nuclear chromosome segregation
FOA15_RS15490	COG0552	protein localization to endoplasmic reticulum
FOA15_RS15495	COG1272	protein, Hemolysin III
FOA15_RS15500	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FOA15_RS15505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOA15_RS15510	COG0228	four-way junction DNA binding
FOA15_RS15520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOA15_RS15525	COG0336	Belongs to the RNA methyltransferase TrmD family
FOA15_RS15530	COG0335	large ribosomal subunit rRNA binding
FOA15_RS15545	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOA15_RS15555	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOA15_RS15560	COG0792	nuclease activity
FOA15_RS15570	COG0606	chelatase, subunit chli
FOA15_RS15575	COG1764	response to oxidative stress
FOA15_RS15580	COG1846	Transcriptional regulator
FOA15_RS15585	COG0045	succinate-CoA ligase (ADP-forming) activity
FOA15_RS15590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOA15_RS15595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOA15_RS15595	COG0758	DNA mediated transformation
FOA15_RS15600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOA15_RS15605	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FOA15_RS15610	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOA15_RS15615	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOA15_RS15620	COG1815	bacterial-type flagellum-dependent cell motility
FOA15_RS15625	COG1558	bacterial-type flagellum-dependent cell motility
FOA15_RS15630	COG1677	Flagellar hook-basal body complex protein FliE
FOA15_RS15635	COG1766	The M ring may be actively involved in energy transduction
FOA15_RS15640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOA15_RS15650	COG1157	protein secretion by the type III secretion system
FOA15_RS15655	COG2882	bacterial-type flagellum organization
FOA15_RS15670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOA15_RS15680	COG4786	Flagellar basal body rod
FOA15_RS15695	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOA15_RS15700	COG1776	CheC inhibitor of MCP methylation
FOA15_RS15700	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOA15_RS15705	COG2201	protein-glutamate methylesterase activity
FOA15_RS15710	COG3190	flagellar
FOA15_RS15715	COG1338	Plays a role in the flagellum-specific transport system
FOA15_RS15720	COG1987	bacterial-type flagellum assembly
FOA15_RS15725	COG1684	flagellar biosynthetic protein fliR
FOA15_RS15730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOA15_RS15735	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOA15_RS15740	COG1419	protein localization to endoplasmic reticulum
FOA15_RS15745	COG0455	bacterial-type flagellum organization
FOA15_RS15750	COG2201	protein-glutamate methylesterase activity
FOA15_RS15755	COG2198	Histidine kinase
FOA15_RS15755	COG0643	Histidine kinase
FOA15_RS15765	COG1776	CheC inhibitor of MCP methylation
FOA15_RS15770	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FOA15_RS15780	COG1191	sigma factor activity
FOA15_RS15805	COG0052	Belongs to the universal ribosomal protein uS2 family
FOA15_RS15810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOA15_RS15815	COG0528	UMP kinase activity
FOA15_RS15820	COG0233	cytoplasmic translational termination
FOA15_RS15825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOA15_RS15830	COG4589	Belongs to the CDS family
FOA15_RS15835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOA15_RS15840	COG0750	zinc metalloprotease
FOA15_RS15845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOA15_RS15850	COG2176	DNA-directed DNA polymerase activity
FOA15_RS15855	COG0779	Required for maturation of 30S ribosomal subunits
FOA15_RS15860	COG0195	Participates in both transcription termination and antitermination
FOA15_RS15870	COG1358	cellular component organization or biogenesis
FOA15_RS15875	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOA15_RS15880	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOA15_RS15885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOA15_RS15890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOA15_RS15895	COG0196	riboflavin kinase activity
FOA15_RS15900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOA15_RS15905	COG1185	polyribonucleotide nucleotidyltransferase activity
FOA15_RS15910	COG0726	polysaccharide deacetylase
FOA15_RS15915	COG0612	Peptidase, M16
FOA15_RS15920	COG0756	dUTP diphosphatase activity
FOA15_RS15925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOA15_RS15930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOA15_RS15935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOA15_RS15940	COG0527	aspartate kinase activity
FOA15_RS15945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOA15_RS15950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOA15_RS15955	COG0740	serine-type endopeptidase activity
FOA15_RS15965	COG1674	ftsk spoiiie
FOA15_RS15965	COG4980	gas vesicle protein
FOA15_RS15975	COG0612	Peptidase, M16
FOA15_RS15980	COG0612	Peptidase, M16
FOA15_RS15985	COG0300	oxidoreductase activity
FOA15_RS16000	COG1426	Protein conserved in bacteria
FOA15_RS16015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOA15_RS16020	COG1058	Belongs to the CinA family
FOA15_RS16020	COG1546	Belongs to the CinA family
FOA15_RS16030	COG2137	regulation of response to DNA damage stimulus
FOA15_RS16040	COG1692	metallophosphoesterase
FOA15_RS16045	COG2359	stage V sporulation protein S
FOA15_RS16055	COG4869	propanediol catabolic process
FOA15_RS16060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOA15_RS16065	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOA15_RS16080	COG1335	isochorismatase
FOA15_RS16085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOA15_RS16090	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOA15_RS16100	COG0018	arginyl-trna synthetase
FOA15_RS16110	COG1132	(ABC) transporter
FOA15_RS16115	COG1132	(ABC) transporter
FOA15_RS16130	COG2707	UPF0756 membrane protein
FOA15_RS16135	COG0492	ferredoxin-NADP+ reductase activity
FOA15_RS16140	COG0640	Transcriptional regulator
FOA15_RS16155	COG1376	ErfK ybiS ycfS ynhG family protein
FOA15_RS16200	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS16230	COG1518	maintenance of DNA repeat elements
FOA15_RS16235	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FOA15_RS16250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOA15_RS16265	COG1653	transport
FOA15_RS16275	COG0395	ABC-type sugar transport system, permease component
FOA15_RS16280	COG1643	Atp-dependent helicase
FOA15_RS16305	COG3599	regulation of cell shape
FOA15_RS16310	COG1959	2 iron, 2 sulfur cluster binding
FOA15_RS16340	COG1733	regulation of RNA biosynthetic process
FOA15_RS16345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOA15_RS16350	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOA15_RS16355	COG2135	peptidase activity
FOA15_RS16360	COG0477	Major facilitator Superfamily
FOA15_RS16365	COG1764	response to oxidative stress
FOA15_RS16370	COG2706	6-phosphogluconolactonase activity
FOA15_RS16390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOA15_RS16395	COG1404	Belongs to the peptidase S8 family
FOA15_RS16405	COG3527	Alpha-acetolactate decarboxylase
FOA15_RS16410	COG0028	Belongs to the TPP enzyme family
FOA15_RS16415	COG1904	glucuronate isomerase
FOA15_RS16420	COG2211	Major facilitator Superfamily
FOA15_RS16425	COG1609	Transcriptional regulator
FOA15_RS16430	COG0028	Belongs to the TPP enzyme family
FOA15_RS16435	COG0246	Mannitol dehydrogenase
FOA15_RS16440	COG2721	sulfolactate sulfo-lyase activity
FOA15_RS16465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOA15_RS16470	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOA15_RS16475	COG0058	SHG alpha-glucan phosphorylase activity
FOA15_RS16495	COG0667	Aldo Keto reductase
FOA15_RS16505	COG0697	spore germination
FOA15_RS16510	COG0523	cobalamin synthesis protein
FOA15_RS16515	COG2329	Antibiotic biosynthesis monooxygenase
FOA15_RS16535	COG5002	protein histidine kinase activity
FOA15_RS16540	COG2323	membrane
FOA15_RS16545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOA15_RS16550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOA15_RS16555	COG0431	NADPH-dependent FMN reductase
FOA15_RS16560	COG0583	DNA-binding transcription factor activity
FOA15_RS16565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOA15_RS16570	COG0765	amino acid transport
FOA15_RS16575	COG0765	amino acid transport
FOA15_RS16580	COG1126	abc transporter atp-binding protein
FOA15_RS16585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOA15_RS16590	COG1473	amidohydrolase
FOA15_RS16615	COG0747	negative chemotaxis
FOA15_RS16620	COG0601	transmembrane transport
FOA15_RS16625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOA15_RS16630	COG0444	Belongs to the ABC transporter superfamily
FOA15_RS16635	COG4608	Belongs to the ABC transporter superfamily
FOA15_RS16655	COG5002	protein histidine kinase activity
FOA15_RS16660	COG2132	Multicopper oxidase
FOA15_RS16675	COG0745	RESPONSE REGULATOR receiver
FOA15_RS16700	COG1714	RDD family
FOA15_RS16715	COG1199	ATP-dependent helicase activity
FOA15_RS16725	COG1609	Transcriptional regulator
FOA15_RS16730	COG1879	ABC-type sugar transport system periplasmic component
FOA15_RS16735	COG1129	ABC transporter
FOA15_RS16740	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOA15_RS16745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOA15_RS16750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS16760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOA15_RS16765	COG0626	cystathionine gamma-synthase activity
FOA15_RS16830	COG2814	Major facilitator Superfamily
FOA15_RS16845	COG0254	rRNA binding
FOA15_RS16850	COG0523	cobalamin synthesis protein
FOA15_RS16860	COG0701	Predicted permease
FOA15_RS16865	COG0523	cobalamin synthesis protein
FOA15_RS16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS16880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOA15_RS16885	COG1121	(ABC) transporter
FOA15_RS16890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOA15_RS16895	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOA15_RS16905	COG2201	protein-glutamate methylesterase activity
FOA15_RS16945	COG1469	GTP cyclohydrolase I activity
FOA15_RS16955	COG2814	Major facilitator Superfamily
FOA15_RS16960	COG4264	IucA IucC family
FOA15_RS16965	COG4264	IucA IucC family
FOA15_RS16975	COG0019	diaminopimelate decarboxylase activity
FOA15_RS16980	COG4264	IucA IucC family
FOA15_RS16985	COG0662	Cupin 2, conserved barrel domain protein
FOA15_RS16985	COG2207	Transcriptional regulator
FOA15_RS16990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOA15_RS16995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS17000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS17005	COG1120	ATPase activity
FOA15_RS17015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOA15_RS17045	COG1215	transferase activity, transferring glycosyl groups
FOA15_RS17050	COG1216	Glycosyl transferase, family 2
FOA15_RS17065	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS17065	COG3347	Dehydrogenase
FOA15_RS17070	COG4952	isomerase
FOA15_RS17075	COG1070	Carbohydrate kinase
FOA15_RS17080	COG1349	DNA-binding transcription factor activity
FOA15_RS17085	COG0247	lactate metabolic process
FOA15_RS17090	COG1139	Iron-sulfur cluster binding protein
FOA15_RS17095	COG1556	Lactate utilization protein
FOA15_RS17100	COG1609	Transcriptional regulator
FOA15_RS17105	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS17110	COG0697	spore germination
FOA15_RS17115	COG3711	transcriptional antiterminator
FOA15_RS17120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS17120	COG2190	(PTS) system
FOA15_RS17120	COG1263	PTS System
FOA15_RS17125	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS17160	COG2755	lipolytic protein G-D-S-L family
FOA15_RS17160	COG3401	FG-GAP repeat protein
FOA15_RS17185	COG1136	(ABC) transporter
FOA15_RS17190	COG1136	(ABC) transporter
FOA15_RS17190	COG0577	efflux transmembrane transporter activity
FOA15_RS17195	COG0517	IMP dehydrogenase activity
FOA15_RS17200	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOA15_RS17205	COG1494	fructose-1,6-bisphosphatase
FOA15_RS17215	COG1132	(ABC) transporter
FOA15_RS17220	COG1132	(ABC) transporter
FOA15_RS17250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOA15_RS17255	COG1073	alpha beta
FOA15_RS17270	COG2801	Transposase and inactivated derivatives
FOA15_RS17275	COG1827	regulation of RNA biosynthetic process
FOA15_RS17280	COG1104	cysteine desulfurase activity
FOA15_RS17285	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOA15_RS17310	COG0671	phosphoesterase, PA-phosphatase related
FOA15_RS17315	COG0745	RESPONSE REGULATOR receiver
FOA15_RS17320	COG3850	Histidine kinase
FOA15_RS17320	COG5002	protein histidine kinase activity
FOA15_RS17325	COG0791	NLP P60 protein
FOA15_RS17330	COG0438	transferase activity, transferring glycosyl groups
FOA15_RS17350	COG0189	ligase activity
FOA15_RS17355	COG2323	membrane
FOA15_RS17360	COG2140	Oxalate decarboxylase
FOA15_RS17365	COG1119	ATPase activity
FOA15_RS17370	COG3874	Sporulation protein YtfJ
FOA15_RS17375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOA15_RS17420	COG0110	maltose O-acetyltransferase activity
FOA15_RS17430	COG2801	Transposase and inactivated derivatives
FOA15_RS17445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOA15_RS17450	COG0563	adenylate kinase activity
FOA15_RS17460	COG3511	phospholipase C
FOA15_RS17465	COG0745	RESPONSE REGULATOR receiver
FOA15_RS17470	COG5002	protein histidine kinase activity
FOA15_RS17480	COG0217	transcriptional regulatory protein
FOA15_RS17495	COG2140	Oxalate decarboxylase
FOA15_RS17500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOA15_RS17510	COG0622	Phosphoesterase
FOA15_RS17520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOA15_RS17540	COG2801	Transposase and inactivated derivatives
FOA15_RS17555	COG0583	DNA-binding transcription factor activity
FOA15_RS17565	COG2814	Major facilitator Superfamily
FOA15_RS17580	COG1187	pseudouridine synthase activity
FOA15_RS17625	COG1396	sequence-specific DNA binding
FOA15_RS17630	COG1971	Probably functions as a manganese efflux pump
FOA15_RS17645	COG3507	Belongs to the glycosyl hydrolase 43 family
FOA15_RS17650	COG3507	Belongs to the glycosyl hydrolase 43 family
FOA15_RS17655	COG1331	Highly conserved protein containing a thioredoxin domain
FOA15_RS17660	COG0840	transmembrane signaling receptor activity
FOA15_RS17670	COG0745	RESPONSE REGULATOR receiver
FOA15_RS17680	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOA15_RS17685	COG3706	GGDEF domain
FOA15_RS17690	COG3459	Glycosyltransferase 36 associated
FOA15_RS17695	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FOA15_RS17705	COG2363	Small membrane protein
FOA15_RS17710	COG5297	Belongs to the glycosyl hydrolase family 6
FOA15_RS17710	COG4447	cellulose binding
FOA15_RS17715	COG1528	Iron-storage protein
FOA15_RS17725	COG0456	acetyltransferase
FOA15_RS17750	COG4335	DNA alkylation repair
FOA15_RS17755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOA15_RS17775	COG0425	Belongs to the sulfur carrier protein TusA family
FOA15_RS17775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOA15_RS17780	COG2210	Belongs to the sulfur carrier protein TusA family
FOA15_RS17785	COG1937	Protein conserved in bacteria
FOA15_RS17805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOA15_RS17815	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS17830	COG0457	Tetratricopeptide repeat
FOA15_RS17845	COG1309	transcriptional regulator
FOA15_RS17850	COG2814	Major facilitator Superfamily
FOA15_RS17855	COG1011	Hydrolase
FOA15_RS17865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS17865	COG1263	PTS System
FOA15_RS17865	COG2190	(PTS) system
FOA15_RS17890	COG1175	transmembrane transport
FOA15_RS17895	COG0395	ABC-type sugar transport system, permease component
FOA15_RS17905	COG2755	lipolytic protein G-D-S-L family
FOA15_RS17915	COG3830	Belongs to the UPF0237 family
FOA15_RS17915	COG0560	Phosphoserine phosphatase
FOA15_RS17925	COG0697	spore germination
FOA15_RS17945	COG0697	spore germination
FOA15_RS17950	COG2207	Transcriptional regulator
FOA15_RS17950	COG1917	Cupin 2, conserved barrel domain protein
FOA15_RS17980	COG3706	GGDEF domain
FOA15_RS17980	COG2203	Gaf domain
FOA15_RS17980	COG4251	negative regulation of phosphorylation
FOA15_RS17980	COG5001	Diguanylate cyclase
FOA15_RS17985	COG1064	alcohol dehydrogenase
FOA15_RS17990	COG1064	alcohol dehydrogenase
FOA15_RS17995	COG0789	Transcriptional regulator
FOA15_RS18000	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOA15_RS18005	COG0789	Transcriptional regulator
FOA15_RS18005	COG4978	Transcriptional regulator
FOA15_RS18010	COG0456	acetyltransferase
FOA15_RS18020	COG0477	Major facilitator Superfamily
FOA15_RS18025	COG0583	DNA-binding transcription factor activity
FOA15_RS18055	COG0444	Belongs to the ABC transporter superfamily
FOA15_RS18060	COG4608	Belongs to the ABC transporter superfamily
FOA15_RS18070	COG1228	amidohydrolase
FOA15_RS18075	COG2207	Transcriptional regulator
FOA15_RS18085	COG1175	transmembrane transport
FOA15_RS18100	COG0583	DNA-binding transcription factor activity
FOA15_RS18110	COG1794	racemase activity, acting on amino acids and derivatives
FOA15_RS18115	COG1027	Aspartate ammonia-lyase
FOA15_RS18125	COG0531	amino acid
FOA15_RS18130	COG0697	spore germination
FOA15_RS18145	COG0154	amidase activity
FOA15_RS18150	COG4221	oxidoreductase activity
FOA15_RS18155	COG0789	Transcriptional regulator
FOA15_RS18165	COG1301	dicarboxylic acid transport
FOA15_RS18175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOA15_RS18180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOA15_RS18185	COG1687	branched-chain amino acid
FOA15_RS18220	COG3507	Belongs to the glycosyl hydrolase 43 family
FOA15_RS18225	COG2364	Membrane
FOA15_RS18230	COG1846	Transcriptional regulator
FOA15_RS18235	COG0456	acetyltransferase
FOA15_RS18240	COG3711	transcriptional antiterminator
FOA15_RS18245	COG2190	(PTS) system
FOA15_RS18245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS18245	COG1263	PTS System
FOA15_RS18255	COG1309	transcriptional regulator
FOA15_RS18270	COG2070	2-Nitropropane dioxygenase
FOA15_RS18275	COG3848	Pyruvate phosphate dikinase
FOA15_RS18275	COG0574	Belongs to the PEP-utilizing enzyme family
FOA15_RS18305	COG0697	spore germination
FOA15_RS18320	COG0531	amino acid
FOA15_RS18325	COG1349	DNA-binding transcription factor activity
FOA15_RS18335	COG1175	transmembrane transport
FOA15_RS18340	COG0395	ABC-type sugar transport system, permease component
FOA15_RS18345	COG1653	transport
FOA15_RS18360	COG1349	DNA-binding transcription factor activity
FOA15_RS18380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOA15_RS18385	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOA15_RS18400	COG1554	hydrolase, family 65, central catalytic
FOA15_RS18410	COG1175	transmembrane transport
FOA15_RS18415	COG0395	ABC-type sugar transport system, permease component
FOA15_RS18425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOA15_RS18430	COG0366	Alpha amylase catalytic
FOA15_RS18445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOA15_RS18445	COG0456	acetyltransferase
FOA15_RS18465	COG1733	regulation of RNA biosynthetic process
FOA15_RS18470	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOA15_RS18475	COG1940	carbohydrate kinase activity
FOA15_RS18480	COG0363	glucosamine-6-phosphate deaminase activity
FOA15_RS18495	COG1472	Belongs to the glycosyl hydrolase 3 family
FOA15_RS18500	COG4209	transmembrane transport
FOA15_RS18505	COG0395	ABC-type sugar transport system, permease component
FOA15_RS18515	COG1396	sequence-specific DNA binding
FOA15_RS18525	COG0681	Belongs to the peptidase S26 family
FOA15_RS18560	COG0656	L-ascorbic acid biosynthetic process
FOA15_RS18570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOA15_RS18575	COG1309	transcriptional regulator
FOA15_RS18585	COG3976	FMN-binding domain protein
FOA15_RS18585	COG0431	NADPH-dependent FMN reductase
FOA15_RS18585	COG1053	succinate dehydrogenase
FOA15_RS18595	COG0604	alcohol dehydrogenase
FOA15_RS18600	COG1609	Transcriptional regulator
FOA15_RS18610	COG0583	DNA-binding transcription factor activity
FOA15_RS18615	COG1012	belongs to the aldehyde dehydrogenase family
FOA15_RS18620	COG3711	transcriptional antiterminator
FOA15_RS18625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS18625	COG1263	PTS System
FOA15_RS18625	COG2190	(PTS) system
FOA15_RS18630	COG3394	polysaccharide catabolic process
FOA15_RS18640	COG0583	DNA-binding transcription factor activity
FOA15_RS18650	COG0477	Major facilitator Superfamily
FOA15_RS18660	COG2070	2-Nitropropane dioxygenase
FOA15_RS18665	COG1942	4-Oxalocrotonate Tautomerase
FOA15_RS18695	COG0366	Alpha amylase catalytic
FOA15_RS18700	COG5520	Belongs to the glycosyl hydrolase 30 family
FOA15_RS18705	COG3507	Belongs to the glycosyl hydrolase 43 family
FOA15_RS18720	COG0667	Aldo Keto reductase
FOA15_RS18725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOA15_RS18730	COG2814	Major facilitator Superfamily
FOA15_RS18735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOA15_RS18765	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS18770	COG2207	Transcriptional regulator
FOA15_RS18780	COG0778	Nitroreductase
FOA15_RS18785	COG1959	2 iron, 2 sulfur cluster binding
FOA15_RS18790	COG4978	Transcriptional regulator
FOA15_RS18790	COG0789	Transcriptional regulator
FOA15_RS18795	COG0534	Mate efflux family protein
FOA15_RS18800	COG0395	ABC-type sugar transport system, permease component
FOA15_RS18805	COG1175	transmembrane transport
FOA15_RS18820	COG4753	response regulator
FOA15_RS18820	COG2207	Transcriptional regulator
FOA15_RS18825	COG2972	Histidine kinase
FOA15_RS18835	COG1879	ABC-type sugar transport system periplasmic component
FOA15_RS18845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOA15_RS18855	COG2323	membrane
FOA15_RS18865	COG1064	alcohol dehydrogenase
FOA15_RS18875	COG0673	inositol 2-dehydrogenase activity
FOA15_RS18885	COG0673	inositol 2-dehydrogenase activity
FOA15_RS18890	COG1609	Transcriptional regulator
FOA15_RS18900	COG1609	Transcriptional regulator
FOA15_RS18915	COG0667	Aldo Keto reductase
FOA15_RS18920	COG0583	DNA-binding transcription factor activity
FOA15_RS18935	COG4974	Belongs to the 'phage' integrase family
FOA15_RS18955	COG2197	response regulator
FOA15_RS18960	COG4585	Histidine kinase
FOA15_RS18965	COG1131	(ABC) transporter
FOA15_RS18990	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS19000	COG0583	DNA-binding transcription factor activity
FOA15_RS19010	COG2814	Major facilitator Superfamily
FOA15_RS19015	COG2801	Transposase and inactivated derivatives
FOA15_RS19030	COG1309	transcriptional regulator
FOA15_RS19035	COG0477	Major facilitator Superfamily
FOA15_RS19045	COG0601	transmembrane transport
FOA15_RS19050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOA15_RS19065	COG0534	Mate efflux family protein
FOA15_RS19070	COG0753	catalase activity
FOA15_RS19075	COG0529	Catalyzes the synthesis of activated sulfate
FOA15_RS19100	COG2066	Belongs to the glutaminase family
FOA15_RS19105	COG2514	catechol 2,3-dioxygenase activity
FOA15_RS19110	COG2259	Doxx family
FOA15_RS19125	COG4632	Exopolysaccharide biosynthesis protein
FOA15_RS19125	COG5434	Belongs to the glycosyl hydrolase 28 family
FOA15_RS19140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOA15_RS19145	COG2186	Transcriptional regulator
FOA15_RS19155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOA15_RS19165	COG2309	aminopeptidase activity
FOA15_RS19180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOA15_RS19185	COG1253	flavin adenine dinucleotide binding
FOA15_RS19195	COG3773	Cell wall hydrolase
FOA15_RS19200	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS19220	COG0531	amino acid
FOA15_RS19225	COG0039	L-malate dehydrogenase activity
FOA15_RS19245	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOA15_RS19260	COG1846	Transcriptional regulator
FOA15_RS19270	COG1695	Transcriptional regulator
FOA15_RS19280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOA15_RS19285	COG1193	negative regulation of DNA recombination
FOA15_RS19290	COG1940	carbohydrate kinase activity
FOA15_RS19305	COG4974	Belongs to the 'phage' integrase family
FOA15_RS19315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS19320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOA15_RS19325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOA15_RS19330	COG1132	(ABC) transporter
FOA15_RS19335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOA15_RS19340	COG1879	ABC-type sugar transport system periplasmic component
FOA15_RS19345	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOA15_RS19350	COG1129	ABC transporter
FOA15_RS19360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOA15_RS19365	COG1609	Transcriptional regulator
FOA15_RS19370	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOA15_RS19375	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS19405	COG4974	Belongs to the 'phage' integrase family
FOA15_RS19410	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOA15_RS19415	COG0303	'Molybdopterin
FOA15_RS19435	COG1842	Phage shock protein A
FOA15_RS19440	COG1902	pentaerythritol trinitrate reductase activity
FOA15_RS19450	COG3584	3D domain protein
FOA15_RS19450	COG1388	LysM domain
FOA15_RS19455	COG1126	abc transporter atp-binding protein
FOA15_RS19460	COG0765	amino acid transport
FOA15_RS19465	COG1473	amidohydrolase
FOA15_RS19470	COG0297	glycogen (starch) synthase activity
FOA15_RS19480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOA15_RS19485	COG5002	protein histidine kinase activity
FOA15_RS19490	COG0745	RESPONSE REGULATOR receiver
FOA15_RS19505	COG0477	Major facilitator Superfamily
FOA15_RS19530	COG0667	Aldo Keto reductase
FOA15_RS19540	COG0493	'glutamate synthase
FOA15_RS19545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOA15_RS19550	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOA15_RS19560	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOA15_RS19565	COG0022	dehydrogenase e1 component
FOA15_RS19580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOA15_RS19585	COG1564	THIamine pyrophosphokinase
FOA15_RS19595	COG0791	NLP P60 protein
FOA15_RS19600	COG0745	RESPONSE REGULATOR receiver
FOA15_RS19605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOA15_RS19610	COG2022	thiamine diphosphate biosynthetic process
FOA15_RS19615	COG2104	thiamine diphosphate biosynthetic process
FOA15_RS19615	COG2022	thiamine diphosphate biosynthetic process
FOA15_RS19625	COG0352	thiamine-phosphate diphosphorylase activity
FOA15_RS19630	COG0488	(ABC) transporter
FOA15_RS19685	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FOA15_RS19690	COG1119	ATPase activity
FOA15_RS19695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOA15_RS19705	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOA15_RS19710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOA15_RS19725	COG1410	methionine synthase
FOA15_RS19725	COG0646	methionine synthase
FOA15_RS19730	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOA15_RS19735	COG1011	Hydrolase
FOA15_RS19745	COG4224	UPF0291 protein
FOA15_RS19755	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOA15_RS19830	COG4824	toxin secretion phage lysis holin
FOA15_RS19850	COG0174	glutamine synthetase
FOA15_RS19855	COG0789	Transcriptional regulator
FOA15_RS19860	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOA15_RS19865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOA15_RS19870	COG0464	growth
FOA15_RS19885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOA15_RS19890	COG1923	regulation of RNA biosynthetic process
FOA15_RS19895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOA15_RS19900	COG2136	Putative SAM-dependent methyltransferase
FOA15_RS19900	COG2521	methyltransferase
FOA15_RS19905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOA15_RS19910	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOA15_RS19925	COG0583	DNA-binding transcription factor activity
FOA15_RS19930	COG0531	amino acid
FOA15_RS19935	COG4129	membrane
FOA15_RS19940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOA15_RS19945	COG1116	anion transmembrane transporter activity
FOA15_RS19950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOA15_RS19955	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOA15_RS19960	COG0288	reversible hydration of carbon dioxide
FOA15_RS19985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOA15_RS20005	COG1566	PFAM secretion protein HlyD family protein
FOA15_RS20010	COG2814	Major facilitator Superfamily
FOA15_RS20015	COG1566	PFAM secretion protein HlyD family protein
FOA15_RS20025	COG0716	FMN binding
FOA15_RS20040	COG0564	pseudouridine synthase activity
FOA15_RS20045	COG2814	Major facilitator Superfamily
FOA15_RS20050	COG1846	Transcriptional regulator
FOA15_RS20060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOA15_RS20075	COG1131	(ABC) transporter
FOA15_RS20090	COG2340	Cysteine-rich secretory protein family
FOA15_RS20100	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOA15_RS20105	COG1132	(ABC) transporter
FOA15_RS20110	COG1132	(ABC) transporter
FOA15_RS20115	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOA15_RS20125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOA15_RS20135	COG2247	cell wall binding repeat
FOA15_RS20135	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOA15_RS20140	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOA15_RS20145	COG0066	3-isopropylmalate dehydratase activity
FOA15_RS20150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOA15_RS20175	COG2423	ornithine cyclodeaminase activity
FOA15_RS20180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOA15_RS20190	COG0529	Catalyzes the synthesis of activated sulfate
FOA15_RS20205	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOA15_RS20225	COG3383	formate dehydrogenase (NAD+) activity
FOA15_RS20240	COG0493	'glutamate synthase
FOA15_RS20240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOA15_RS20245	COG1027	Aspartate ammonia-lyase
FOA15_RS20250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOA15_RS20260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOA15_RS20265	COG1785	Belongs to the alkaline phosphatase family
FOA15_RS20270	COG0583	DNA-binding transcription factor activity
FOA15_RS20285	COG5634	Uncharacterized conserved protein (DUF2278)
FOA15_RS20295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOA15_RS20300	COG0436	Aminotransferase
FOA15_RS20305	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOA15_RS20310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOA15_RS20320	COG1850	ribulose-bisphosphate carboxylase activity
FOA15_RS20325	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FOA15_RS20330	COG0235	Class ii aldolase
FOA15_RS20335	COG1733	regulation of RNA biosynthetic process
FOA15_RS20340	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOA15_RS20345	COG0596	Alpha beta hydrolase
FOA15_RS20360	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS20365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOA15_RS20390	COG3935	DnaD domain protein
FOA15_RS20395	COG0017	Asparaginyl-tRNA synthetase
FOA15_RS20400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOA15_RS20405	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOA15_RS20410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOA15_RS20430	COG0402	S-adenosylhomocysteine deaminase activity
FOA15_RS20435	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FOA15_RS20440	COG1199	ATP-dependent helicase activity
FOA15_RS20440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOA15_RS20455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOA15_RS20460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOA15_RS20470	COG0617	tRNA 3'-terminal CCA addition
FOA15_RS20475	COG0438	transferase activity, transferring glycosyl groups
FOA15_RS20480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOA15_RS20485	COG1803	Methylglyoxal synthase
FOA15_RS20490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOA15_RS20500	COG1694	Mazg nucleotide pyrophosphohydrolase
FOA15_RS20505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOA15_RS20515	COG4347	Protein of unknown function (DUF1405)
FOA15_RS20535	COG0588	phosphoglycerate mutase activity
FOA15_RS20550	COG2226	methyltransferase
FOA15_RS20555	COG0287	Prephenate dehydrogenase
FOA15_RS20560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOA15_RS20565	COG0159	tryptophan synthase activity
FOA15_RS20570	COG0133	tryptophan synthase activity
FOA15_RS20575	COG0135	phosphoribosylanthranilate isomerase activity
FOA15_RS20585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOA15_RS20595	COG4401	Chorismate mutase type I
FOA15_RS20600	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOA15_RS20605	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOA15_RS20610	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOA15_RS20615	COG0105	UTP biosynthetic process
FOA15_RS20635	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FOA15_RS20640	COG2226	methyltransferase
FOA15_RS20665	COG0776	regulation of translation
FOA15_RS20670	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOA15_RS20675	COG1129	ABC transporter
FOA15_RS20695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOA15_RS20720	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOA15_RS20725	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOA15_RS20730	COG1160	GTP binding
FOA15_RS20750	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FOA15_RS20755	COG2959	enzyme of heme biosynthesis
FOA15_RS20760	COG2339	peptidase activity
FOA15_RS20765	COG4862	establishment of competence for transformation
FOA15_RS20790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOA15_RS20795	COG5002	protein histidine kinase activity
FOA15_RS20800	COG0745	RESPONSE REGULATOR receiver
FOA15_RS20805	COG1187	pseudouridine synthase activity
FOA15_RS20810	COG0700	Nucleoside recognition
FOA15_RS20815	COG2715	membrane protein required for spore maturation
FOA15_RS20820	COG1686	Belongs to the peptidase S11 family
FOA15_RS20830	COG3874	Sporulation protein YtfJ
FOA15_RS20840	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOA15_RS20845	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOA15_RS20855	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOA15_RS20855	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOA15_RS20860	COG0307	riboflavin synthase, alpha
FOA15_RS20870	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOA15_RS20880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOA15_RS20885	COG0019	diaminopimelate decarboxylase activity
FOA15_RS20890	COG0697	spore germination
FOA15_RS20910	COG2172	sigma factor antagonist activity
FOA15_RS20915	COG1366	Belongs to the anti-sigma-factor antagonist family
FOA15_RS20920	COG1686	Belongs to the peptidase S11 family
FOA15_RS20925	COG3307	-O-antigen
FOA15_RS20935	COG4974	Belongs to the 'phage' integrase family
FOA15_RS20945	COG0735	belongs to the Fur family
FOA15_RS20950	COG1300	Membrane
FOA15_RS20955	COG1379	DNA repair
FOA15_RS20970	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOA15_RS20980	COG0321	lipoyl(octanoyl) transferase activity
FOA15_RS20985	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOA15_RS20990	COG0022	dehydrogenase e1 component
FOA15_RS20995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOA15_RS21000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOA15_RS21010	COG1435	thymidine kinase activity
FOA15_RS21015	COG4326	sporulation control protein
FOA15_RS21025	COG0840	transmembrane signaling receptor activity
FOA15_RS21035	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS21040	COG0745	RESPONSE REGULATOR receiver
FOA15_RS21045	COG0750	zinc metalloprotease
FOA15_RS21050	COG0497	DNA recombination
FOA15_RS21055	COG1438	arginine binding
FOA15_RS21065	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOA15_RS21070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOA15_RS21080	COG1722	exodeoxyribonuclease VII activity
FOA15_RS21085	COG1570	exodeoxyribonuclease VII activity
FOA15_RS21090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOA15_RS21095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOA15_RS21110	COG1302	Protein conserved in bacteria
FOA15_RS21115	COG0439	Biotin carboxylase
FOA15_RS21120	COG0511	ligase activity, forming carbon-carbon bonds
FOA15_RS21160	COG3854	ATPases associated with a variety of cellular activities
FOA15_RS21170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOA15_RS21175	COG0006	proline dipeptidase activity
FOA15_RS21185	COG3872	metal-dependent enzyme
FOA15_RS21195	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOA15_RS21200	COG1649	PFAM Uncharacterised BCR, COG1649
FOA15_RS21205	COG1321	iron dependent repressor
FOA15_RS21215	COG0785	Cytochrome C biogenesis protein
FOA15_RS21220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOA15_RS21220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOA15_RS21225	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOA15_RS21230	COG0735	belongs to the Fur family
FOA15_RS21240	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOA15_RS21245	COG1882	Formate acetyltransferase
FOA15_RS21250	COG1012	belongs to the aldehyde dehydrogenase family
FOA15_RS21250	COG1454	alcohol dehydrogenase
FOA15_RS21255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOA15_RS21260	COG3384	dioxygenase
FOA15_RS21265	COG1733	regulation of RNA biosynthetic process
FOA15_RS21275	COG1082	Xylose isomerase domain protein TIM barrel
FOA15_RS21280	COG0673	inositol 2-dehydrogenase activity
FOA15_RS21290	COG0673	inositol 2-dehydrogenase activity
FOA15_RS21300	COG3534	alpha-L-arabinofuranosidase
FOA15_RS21315	COG0673	inositol 2-dehydrogenase activity
FOA15_RS21320	COG0861	Integral membrane protein TerC family
FOA15_RS21325	COG0398	Pfam SNARE associated Golgi protein
FOA15_RS21330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOA15_RS21330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOA15_RS21340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOA15_RS21355	COG0697	spore germination
FOA15_RS21360	COG0531	amino acid
FOA15_RS21370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOA15_RS21385	COG0583	DNA-binding transcription factor activity
FOA15_RS21390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOA15_RS21395	COG0561	phosphatase activity
FOA15_RS21410	COG1940	carbohydrate kinase activity
FOA15_RS21420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOA15_RS21425	COG1307	EDD domain protein, DegV family
FOA15_RS21430	COG1461	Dihydroxyacetone kinase
FOA15_RS21435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOA15_RS21450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOA15_RS21455	COG1162	GTPase activity
FOA15_RS21460	COG0515	serine threonine protein kinase
FOA15_RS21460	COG2815	serine threonine protein kinase
FOA15_RS21465	COG0631	protein serine/threonine phosphatase activity
FOA15_RS21470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOA15_RS21475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOA15_RS21475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOA15_RS21480	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOA15_RS21485	COG0242	peptide deformylase activity
FOA15_RS21490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOA15_RS21495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOA15_RS21500	COG1758	RNA polymerase activity
FOA15_RS21505	COG0194	GDP metabolic process
FOA15_RS21510	COG2052	Domain of unknown function (DUF370)
FOA15_RS21515	COG1561	YicC-like family, N-terminal region
FOA15_RS21520	COG0646	methionine synthase
FOA15_RS21520	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOA15_RS21530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOA15_RS21535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOA15_RS21545	COG0613	PHP domain protein
FOA15_RS21560	COG4471	UPF0298 protein
FOA15_RS21580	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOA15_RS21585	COG1473	amidohydrolase
FOA15_RS21590	COG0772	Belongs to the SEDS family
FOA15_RS21595	COG1302	Protein conserved in bacteria
FOA15_RS21600	COG0387	Pfam Sodium calcium exchanger
FOA15_RS21605	COG4838	Belongs to the UPF0358 family
FOA15_RS21615	COG2309	aminopeptidase activity
FOA15_RS21625	COG2203	Gaf domain
FOA15_RS21625	COG2199	diguanylate cyclase activity
FOA15_RS21630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOA15_RS21635	COG3708	Transcriptional regulator
FOA15_RS21635	COG2207	Transcriptional regulator
FOA15_RS21640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOA15_RS21650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOA15_RS21655	COG0454	-acetyltransferase
FOA15_RS21660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOA15_RS21665	COG1609	Transcriptional regulator
FOA15_RS21680	COG0693	protein deglycase activity
FOA15_RS21685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOA15_RS21690	COG1263	PTS System
FOA15_RS21690	COG2190	(PTS) system
FOA15_RS21690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS21695	COG1832	CoA-binding protein
FOA15_RS21700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOA15_RS21705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOA15_RS21710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOA15_RS21720	COG4493	Belongs to the UPF0637 family
FOA15_RS21730	COG1982	Orn Lys Arg decarboxylase major
FOA15_RS21745	COG1234	tRNA 3'-trailer cleavage
FOA15_RS21755	COG2153	protein acetylation
FOA15_RS21770	COG2146	nitrite reductase [NAD(P)H] activity
FOA15_RS21775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOA15_RS21780	COG3707	response regulator
FOA15_RS21785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOA15_RS21790	COG0243	molybdopterin cofactor binding
FOA15_RS21795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOA15_RS21800	COG2223	nitrite transmembrane transporter activity
FOA15_RS21805	COG0281	malic enzyme
FOA15_RS21810	COG2801	Transposase and inactivated derivatives
FOA15_RS21830	COG1874	Beta-galactosidase
FOA15_RS21835	COG0395	ABC-type sugar transport system, permease component
FOA15_RS21840	COG4209	transmembrane transport
FOA15_RS21850	COG4753	response regulator
FOA15_RS21850	COG2207	Transcriptional regulator
FOA15_RS21855	COG3275	phosphorelay sensor kinase activity
FOA15_RS21865	COG3209	COG3209 Rhs family protein
FOA15_RS21890	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOA15_RS21905	COG0673	inositol 2-dehydrogenase activity
FOA15_RS21910	COG1082	Xylose isomerase domain protein TIM barrel
FOA15_RS21915	COG4977	sequence-specific DNA binding
FOA15_RS21915	COG1917	Cupin 2, conserved barrel domain protein
FOA15_RS21920	COG1657	PFAM Prenyltransferase squalene oxidase
FOA15_RS22015	COG1742	UPF0060 membrane protein
FOA15_RS22035	COG0371	Dehydrogenase
FOA15_RS22045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOA15_RS22085	COG0583	DNA-binding transcription factor activity
FOA15_RS22090	COG3507	Belongs to the glycosyl hydrolase 43 family
FOA15_RS22100	COG1073	alpha beta
FOA15_RS22110	COG1653	transport
FOA15_RS22115	COG5578	integral membrane protein
FOA15_RS22120	COG4209	transmembrane transport
FOA15_RS22125	COG0395	ABC-type sugar transport system, permease component
FOA15_RS22130	COG2207	Transcriptional regulator
FOA15_RS22135	COG2755	lipolytic protein G-D-S-L family
FOA15_RS22175	COG0284	orotidine-5'-phosphate decarboxylase activity
FOA15_RS22190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOA15_RS22195	COG0540	Belongs to the ATCase OTCase family
FOA15_RS22200	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FOA15_RS22205	COG0564	pseudouridine synthase activity
FOA15_RS22210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOA15_RS22215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOA15_RS22230	COG3599	regulation of cell shape
FOA15_RS22235	COG2302	S4 RNA-binding domain
FOA15_RS22240	COG0762	integral membrane protein
FOA15_RS22245	COG1799	cell septum assembly
FOA15_RS22250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOA15_RS22260	COG1873	PFAM PRC-barrel domain
FOA15_RS22265	COG1191	sigma factor activity
FOA15_RS22270	COG1191	sigma factor activity
FOA15_RS22280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOA15_RS22285	COG0849	cell division
FOA15_RS22290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOA15_RS22295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOA15_RS22300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOA15_RS22310	COG0772	Belongs to the SEDS family
FOA15_RS22315	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOA15_RS22320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOA15_RS22325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOA15_RS22335	COG0768	penicillin binding
FOA15_RS22340	COG0768	penicillin binding
FOA15_RS22350	COG0275	rRNA processing
FOA15_RS22355	COG2001	Belongs to the MraZ family
FOA15_RS22360	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOA15_RS22365	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FOA15_RS22370	COG4608	Belongs to the ABC transporter superfamily
FOA15_RS22375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOA15_RS22380	COG0601	transmembrane transport
FOA15_RS22385	COG4166	transmembrane transport
FOA15_RS22395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOA15_RS22410	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOA15_RS22415	COG1316	TRANSCRIPTIONal
FOA15_RS22430	COG0861	Integral membrane protein TerC family
FOA15_RS22435	COG0861	Integral membrane protein TerC family
FOA15_RS22440	COG0301	tRNA thio-modification
FOA15_RS22445	COG1104	cysteine desulfurase activity
FOA15_RS22450	COG0741	lytic transglycosylase activity
FOA15_RS22480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOA15_RS22485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOA15_RS22495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOA15_RS22500	COG2384	SAM-dependent methyltransferase
FOA15_RS22515	COG0358	DNA primase activity
FOA15_RS22520	COG1671	Belongs to the UPF0178 family
FOA15_RS22525	COG0751	glycine-tRNA ligase activity
FOA15_RS22530	COG0752	glycyl-tRNA synthetase alpha subunit
FOA15_RS22535	COG1381	Involved in DNA repair and RecF pathway recombination
FOA15_RS22545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOA15_RS22550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOA15_RS22555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOA15_RS22560	COG1480	7TM receptor with intracellular HD hydrolase
FOA15_RS22565	COG1702	phosphate starvation-inducible protein PhoH
FOA15_RS22580	COG0531	amino acid
FOA15_RS22590	COG4864	UPF0365 protein
FOA15_RS22595	COG1030	water channel activity
FOA15_RS22600	COG1610	YqeY-like protein
FOA15_RS22605	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOA15_RS22610	COG0537	adenosine 5'-monophosphoramidase activity
FOA15_RS22615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOA15_RS22625	COG0419	ATPase involved in DNA repair
FOA15_RS22630	COG0420	3'-5' exonuclease activity
FOA15_RS22635	COG1074	ATP-dependent DNA helicase activity
FOA15_RS22640	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOA15_RS22650	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOA15_RS22660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOA15_RS22665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOA15_RS22670	COG1994	Peptidase M50
FOA15_RS22695	COG3493	citrate carrier protein
FOA15_RS22700	COG4565	transcriptional regulatory protein
FOA15_RS22705	COG3290	protein histidine kinase activity
FOA15_RS22725	COG1420	regulation of RNA biosynthetic process
FOA15_RS22745	COG0481	GTPase activity
FOA15_RS22755	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOA15_RS22760	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOA15_RS22765	COG0268	Binds directly to 16S ribosomal RNA
FOA15_RS22770	COG1466	dna polymerase III delta subunit
FOA15_RS22780	COG1595	DNA-templated transcription, initiation
FOA15_RS22790	COG0667	Aldo Keto reductase
FOA15_RS22800	COG2333	competence protein COMEC
FOA15_RS22800	COG0658	competence protein
FOA15_RS22810	COG1555	photosystem II stabilization
FOA15_RS22815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOA15_RS22820	COG0495	leucyl-tRNA aminoacylation
FOA15_RS22825	COG2226	methyltransferase
FOA15_RS22830	COG2996	Protein conserved in bacteria
FOA15_RS22835	COG0799	negative regulation of ribosome biogenesis
FOA15_RS22840	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOA15_RS22845	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOA15_RS22850	COG1534	Rna-binding protein
FOA15_RS22855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOA15_RS22860	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOA15_RS22865	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOA15_RS22870	COG1305	Transglutaminase-like
FOA15_RS22880	COG0714	Associated with various cellular activities
FOA15_RS22890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOA15_RS22900	COG1363	Peptidase, m42
FOA15_RS22910	COG1454	alcohol dehydrogenase
FOA15_RS22915	COG4305	rare lipoprotein A
FOA15_RS22920	COG1609	Transcriptional regulator
FOA15_RS22920	COG2207	Transcriptional regulator
FOA15_RS22925	COG1653	transport
FOA15_RS22930	COG0395	ABC-type sugar transport system, permease component
FOA15_RS22935	COG4209	transmembrane transport
FOA15_RS22940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOA15_RS22960	COG3866	Pectate lyase
FOA15_RS22970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOA15_RS23000	COG1819	glycosyl
FOA15_RS23005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOA15_RS23020	COG2801	Transposase and inactivated derivatives
FOA15_RS23060	COG5609	conserved protein (DUF2294)
FOA15_RS23065	COG3420	alginic acid biosynthetic process
FOA15_RS23070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOA15_RS23075	COG0314	molybdopterin synthase activity
FOA15_RS23085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOA15_RS23095	COG3383	formate dehydrogenase (NAD+) activity
FOA15_RS23100	COG2427	Protein of unknown function (DUF1641)
FOA15_RS23115	COG3181	Tripartite tricarboxylate transporter family receptor
FOA15_RS23120	COG2207	Transcriptional regulator
FOA15_RS23140	COG1027	Aspartate ammonia-lyase
FOA15_RS23155	COG0436	Aminotransferase
FOA15_RS23180	COG1177	transmembrane transport
FOA15_RS23185	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOA15_RS23195	COG1473	amidohydrolase
FOA15_RS23200	COG2171	N-acyltransferase activity
FOA15_RS23210	COG0697	spore germination
FOA15_RS23215	COG2897	thiosulfate sulfurtransferase activity
FOA15_RS23325	COG0653	protein targeting
FOA15_RS23330	COG4974	Belongs to the 'phage' integrase family
FOA15_RS23335	COG0840	transmembrane signaling receptor activity
FOA15_RS23345	COG2814	Major facilitator Superfamily
FOA15_RS23350	COG1309	transcriptional regulator
FOA15_RS23370	COG0840	transmembrane signaling receptor activity
FOA15_RS23395	COG1397	ADP-ribosylglycohydrolase
FOA15_RS23405	COG0383	alpha-mannosidase activity
FOA15_RS23465	COG2814	Major facilitator Superfamily
FOA15_RS23470	COG3250	beta-galactosidase activity
FOA15_RS23475	COG4608	Belongs to the ABC transporter superfamily
FOA15_RS23480	COG0444	Belongs to the ABC transporter superfamily
FOA15_RS23490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOA15_RS23495	COG0747	negative chemotaxis
FOA15_RS23505	COG0601	transmembrane transport
FOA15_RS23510	COG2814	Major facilitator Superfamily
FOA15_RS23525	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS23530	COG1263	PTS System
FOA15_RS23530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS23530	COG2190	(PTS) system
FOA15_RS23535	COG3711	transcriptional antiterminator
FOA15_RS23540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOA15_RS23550	COG0314	molybdopterin synthase activity
FOA15_RS23555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOA15_RS23560	COG2223	nitrite transmembrane transporter activity
FOA15_RS23565	COG2197	response regulator
FOA15_RS23570	COG4585	Histidine kinase
FOA15_RS23580	COG2181	nitrate reductase activity
FOA15_RS23590	COG1140	nitrate reductase beta subunit
FOA15_RS23595	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOA15_RS23600	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOA15_RS23610	COG0535	radical SAM domain protein
FOA15_RS23645	COG2169	Transcriptional regulator
FOA15_RS23655	COG2814	Major facilitator Superfamily
FOA15_RS23675	COG1063	alcohol dehydrogenase
FOA15_RS23680	COG4977	sequence-specific DNA binding
FOA15_RS23685	COG1113	amino acid transport
FOA15_RS23695	COG0778	Nitroreductase
FOA15_RS23700	COG1846	Transcriptional regulator
FOA15_RS23705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOA15_RS23715	COG0312	modulator of DNA gyrase
FOA15_RS23720	COG0312	modulator of DNA gyrase
FOA15_RS23750	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOA15_RS23760	COG0693	protein deglycase activity
FOA15_RS23795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOA15_RS23800	COG0549	Belongs to the carbamate kinase family
FOA15_RS23845	COG4753	response regulator
FOA15_RS23845	COG2207	Transcriptional regulator
FOA15_RS23850	COG2972	Histidine kinase
FOA15_RS23855	COG0395	ABC-type sugar transport system, permease component
FOA15_RS23860	COG1175	transmembrane transport
FOA15_RS23865	COG0395	ABC-type sugar transport system, permease component
FOA15_RS23885	COG2972	Histidine kinase
FOA15_RS23890	COG0673	inositol 2-dehydrogenase activity
FOA15_RS23895	COG3615	Tellurite resistance protein tehB
FOA15_RS23895	COG0500	methyltransferase
FOA15_RS23900	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FOA15_RS23910	COG1515	deoxyribonuclease V activity
FOA15_RS23915	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOA15_RS23945	COG3866	Pectate lyase
FOA15_RS23950	COG0444	Belongs to the ABC transporter superfamily
FOA15_RS23955	COG2205	protein histidine kinase activity
FOA15_RS23955	COG2770	Histidine kinase
FOA15_RS23960	COG0745	RESPONSE REGULATOR receiver
FOA15_RS23975	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOA15_RS24000	COG1902	pentaerythritol trinitrate reductase activity
FOA15_RS24005	COG0789	Transcriptional regulator
FOA15_RS24020	COG4412	M6 family metalloprotease domain protein
FOA15_RS24020	COG1404	Belongs to the peptidase S8 family
FOA15_RS24025	COG4412	M6 family metalloprotease domain protein
FOA15_RS24025	COG1404	Belongs to the peptidase S8 family
FOA15_RS24030	COG0659	secondary active sulfate transmembrane transporter activity
FOA15_RS24045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOA15_RS24055	COG1126	abc transporter atp-binding protein
FOA15_RS24060	COG0765	amino acid transport
FOA15_RS24065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOA15_RS24075	COG2261	transglycosylase associated protein
FOA15_RS24085	COG3458	cephalosporin-C deacetylase activity
FOA15_RS24095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOA15_RS24110	COG0740	serine-type endopeptidase activity
FOA15_RS24195	COG1714	RDD family
FOA15_RS24240	COG0484	heat shock protein binding
FOA15_RS24265	COG2223	nitrite transmembrane transporter activity
FOA15_RS24270	COG3279	Response regulator of the LytR AlgR family
FOA15_RS24275	COG3275	phosphorelay sensor kinase activity
FOA15_RS24280	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOA15_RS24285	COG4733	cellulase activity
FOA15_RS24285	COG4447	cellulose binding
FOA15_RS24295	COG1523	belongs to the glycosyl hydrolase 13 family
FOA15_RS24300	COG1132	(ABC) transporter
FOA15_RS24305	COG4988	ABC transporter
FOA15_RS24310	COG0246	Mannitol dehydrogenase
FOA15_RS24315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOA15_RS24320	COG3711	transcriptional antiterminator
FOA15_RS24335	COG0509	glycine decarboxylation via glycine cleavage system
FOA15_RS24340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOA15_RS24345	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOA15_RS24350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOA15_RS24365	COG1263	PTS System
FOA15_RS24365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS24365	COG2190	(PTS) system
FOA15_RS24370	COG3711	transcriptional antiterminator
FOA15_RS24375	COG2268	Band 7 protein
FOA15_RS24385	COG1979	alcohol dehydrogenase
FOA15_RS24395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOA15_RS24400	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOA15_RS24410	COG0667	Aldo Keto reductase
FOA15_RS24420	COG0546	phosphoglycolate phosphatase activity
FOA15_RS24430	COG3594	Acyltransferase
FOA15_RS24435	COG0129	dihydroxy-acid dehydratase activity
FOA15_RS24445	COG0628	permease
FOA15_RS24450	COG0768	penicillin binding
FOA15_RS24455	COG0840	transmembrane signaling receptor activity
FOA15_RS24470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOA15_RS24480	COG3906	Belongs to the UPF0473 family
FOA15_RS24490	COG4472	Bacterial protein of unknown function (DUF965)
FOA15_RS24495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOA15_RS24500	COG0628	permease
FOA15_RS24520	COG1104	cysteine desulfurase activity
FOA15_RS24525	COG1959	2 iron, 2 sulfur cluster binding
FOA15_RS24530	COG0482	sulfurtransferase activity
FOA15_RS24540	COG0641	radical SAM
FOA15_RS24575	COG2326	polyphosphate kinase activity
FOA15_RS24580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOA15_RS24585	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOA15_RS24590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOA15_RS24615	COG0281	malic enzyme
FOA15_RS24630	COG3052	prosthetic group binding
FOA15_RS24640	COG3493	citrate carrier protein
FOA15_RS24645	COG0745	RESPONSE REGULATOR receiver
FOA15_RS24650	COG1132	(ABC) transporter
FOA15_RS24660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOA15_RS24665	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOA15_RS24670	COG0124	histidyl-tRNA synthetase
FOA15_RS24675	COG4221	oxidoreductase activity
FOA15_RS24675	COG3321	synthase
FOA15_RS24675	COG0300	oxidoreductase activity
FOA15_RS24675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOA15_RS24680	COG4221	oxidoreductase activity
FOA15_RS24680	COG3321	synthase
FOA15_RS24680	COG0300	oxidoreductase activity
FOA15_RS24680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOA15_RS24685	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS24685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOA15_RS24685	COG3321	synthase
FOA15_RS24685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOA15_RS24685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOA15_RS24690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOA15_RS24690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOA15_RS24690	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS24690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOA15_RS24690	COG3321	synthase
FOA15_RS24695	COG4221	oxidoreductase activity
FOA15_RS24695	COG3321	synthase
FOA15_RS24695	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS24695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOA15_RS24700	COG0300	oxidoreductase activity
FOA15_RS24700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOA15_RS24700	COG3321	synthase
FOA15_RS24700	COG4221	oxidoreductase activity
FOA15_RS24705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOA15_RS24705	COG1028	Short-chain dehydrogenase reductase Sdr
FOA15_RS24705	COG3321	synthase
FOA15_RS24705	COG4221	oxidoreductase activity
FOA15_RS24710	COG4221	oxidoreductase activity
FOA15_RS24710	COG3321	synthase
FOA15_RS24710	COG0300	oxidoreductase activity
FOA15_RS24710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOA15_RS24715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOA15_RS24715	COG2070	2-Nitropropane dioxygenase
FOA15_RS24730	COG1794	racemase activity, acting on amino acids and derivatives
FOA15_RS24750	COG1309	transcriptional regulator
FOA15_RS24755	COG3848	Pyruvate phosphate dikinase
FOA15_RS24755	COG0574	Belongs to the PEP-utilizing enzyme family
FOA15_RS24770	COG1490	D-aminoacyl-tRNA deacylase activity
FOA15_RS24775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOA15_RS24790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOA15_RS24795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOA15_RS24795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOA15_RS24805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOA15_RS24810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOA15_RS24810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOA15_RS24820	COG2244	polysaccharide biosynthetic process
FOA15_RS24825	COG2323	membrane
FOA15_RS24835	COG1862	Preprotein translocase
FOA15_RS24845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOA15_RS24850	COG2385	sporulation resulting in formation of a cellular spore
FOA15_RS24850	COG2385	sporulation resulting in formation of a cellular spore
FOA15_RS24855	COG2255	four-way junction helicase activity
FOA15_RS24860	COG0632	four-way junction helicase activity
FOA15_RS24865	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOA15_RS24945	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOA15_RS24945	COG1388	LysM domain
FOA15_RS24955	COG0077	Prephenate dehydratase
FOA15_RS24960	COG0083	homoserine kinase activity
FOA15_RS24965	COG0460	homoserine dehydrogenase
FOA15_RS24970	COG4492	Belongs to the UPF0735 family
FOA15_RS24975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOA15_RS24990	COG2868	ribosomal protein
FOA15_RS24995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOA15_RS25000	COG1530	ribonuclease E activity
FOA15_RS25005	COG1994	Peptidase M50
FOA15_RS25015	COG2894	cell division
FOA15_RS25020	COG0850	regulation of cytokinetic process
FOA15_RS25035	COG1077	Cell shape determining protein MreB Mrl
FOA15_RS25040	COG2003	Belongs to the UPF0758 family
FOA15_RS25045	COG0424	maF-like protein
FOA15_RS25060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOA15_RS25065	COG0285	dihydrofolate synthase activity
FOA15_RS25070	COG0525	valine-tRNA ligase activity
FOA15_RS25075	COG1388	LysM domain
FOA15_RS25080	COG0564	pseudouridine synthase activity
FOA15_RS25085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOA15_RS25090	COG0113	porphobilinogen synthase activity
FOA15_RS25105	COG1648	precorrin-2 dehydrogenase activity
FOA15_RS25105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOA15_RS25120	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOA15_RS25130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOA15_RS25140	COG1067	ATP-dependent peptidase activity
FOA15_RS25140	COG0470	DNA polymerase III
FOA15_RS25150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOA15_RS25155	COG0740	serine-type endopeptidase activity
FOA15_RS25160	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOA15_RS25175	COG0708	Exodeoxyribonuclease III
FOA15_RS25180	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS25185	COG0395	ABC-type sugar transport system, permease component
FOA15_RS25190	COG1175	transmembrane transport
FOA15_RS25205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOA15_RS25210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOA15_RS25215	COG1263	PTS System
FOA15_RS25215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS25235	COG3052	prosthetic group binding
FOA15_RS25255	COG0583	DNA-binding transcription factor activity
FOA15_RS25260	COG1115	amino acid carrier protein
FOA15_RS25265	COG2723	6-phospho-beta-galactosidase activity
FOA15_RS25270	COG0673	inositol 2-dehydrogenase activity
FOA15_RS25275	COG0673	inositol 2-dehydrogenase activity
FOA15_RS25280	COG1609	Transcriptional regulator
FOA15_RS25285	COG3711	transcriptional antiterminator
FOA15_RS25290	COG2190	(PTS) system
FOA15_RS25290	COG1263	PTS System
FOA15_RS25290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOA15_RS25300	COG0662	Cupin 2, conserved barrel domain protein
FOA15_RS25300	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOA15_RS25305	COG0745	RESPONSE REGULATOR receiver
FOA15_RS25330	COG0463	Glycosyl transferase, family 2
FOA15_RS25350	COG0281	malic enzyme
FOA15_RS25355	COG0679	Auxin Efflux Carrier
FOA15_RS25360	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOA15_RS25365	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOA15_RS25370	COG0351	phosphomethylpyrimidine kinase
FOA15_RS25435	COG3973	AAA domain
FOA15_RS25440	COG1733	regulation of RNA biosynthetic process
FOA15_RS25450	COG1609	Transcriptional regulator
FOA15_RS25455	COG1486	melibiose metabolic process
FOA15_RS25460	COG4733	cellulase activity
FOA15_RS25460	COG5297	Belongs to the glycosyl hydrolase family 6