locus-tag	class	description
B2K_RS00010	COG0592	DNA-directed DNA polymerase activity
B2K_RS00015	COG2501	S4 domain
B2K_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B2K_RS00030	COG0187	DNA topoisomerase II activity
B2K_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B2K_RS00075	COG0516	GMP reductase activity
B2K_RS00075	COG0517	IMP dehydrogenase activity
B2K_RS00080	COG1686	Belongs to the peptidase S11 family
B2K_RS00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B2K_RS00125	COG3973	AAA domain
B2K_RS00130	COG0024	Methionine aminopeptidase
B2K_RS00155	COG0586	Pfam SNARE associated Golgi protein
B2K_RS00160	COG0590	tRNA wobble adenosine to inosine editing
B2K_RS00175	COG0012	GTP binding
B2K_RS00180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B2K_RS00185	COG2890	protein-(glutamine-N5) methyltransferase activity
B2K_RS00195	COG0009	L-threonylcarbamoyladenylate synthase
B2K_RS00200	COG1971	Probably functions as a manganese efflux pump
B2K_RS00210	COG0698	ribose 5-phosphate isomerase
B2K_RS00215	COG4475	Protein of unknown function (DUF436)
B2K_RS00220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B2K_RS00225	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B2K_RS00230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B2K_RS00245	COG0356	it plays a direct role in the translocation of protons across the membrane
B2K_RS00250	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B2K_RS00255	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B2K_RS00260	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B2K_RS00265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B2K_RS00270	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B2K_RS00275	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B2K_RS00280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B2K_RS00285	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B2K_RS00290	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B2K_RS00295	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B2K_RS00300	COG0649	NAD binding
B2K_RS00305	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B2K_RS00315	COG0839	Belongs to the complex I subunit 6 family
B2K_RS00320	COG0713	ATP synthesis coupled electron transport
B2K_RS00325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B2K_RS00330	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B2K_RS00335	COG1007	ATP synthesis coupled electron transport
B2K_RS00340	COG1846	Transcriptional regulator
B2K_RS00350	COG4836	Membrane
B2K_RS00355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B2K_RS00360	COG2385	sporulation resulting in formation of a cellular spore
B2K_RS00365	COG0739	heme binding
B2K_RS00370	COG1609	Transcriptional regulator
B2K_RS00380	COG4786	Flagellar basal body rod
B2K_RS00400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B2K_RS00405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B2K_RS00420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B2K_RS00445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B2K_RS00455	COG4585	Histidine kinase
B2K_RS00470	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B2K_RS00475	COG1040	competence protein
B2K_RS00495	COG4786	Flagellar basal body rod
B2K_RS00495	COG1256	bacterial-type flagellum assembly
B2K_RS00500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B2K_RS00510	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
B2K_RS00515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B2K_RS00520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B2K_RS00525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B2K_RS00530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B2K_RS00535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B2K_RS00540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B2K_RS00545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B2K_RS00555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B2K_RS00565	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B2K_RS00580	COG1278	Cold shock
B2K_RS00590	COG0653	protein targeting
B2K_RS00595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B2K_RS00600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2K_RS00605	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B2K_RS00610	COG3383	formate dehydrogenase (NAD+) activity
B2K_RS00615	COG5609	conserved protein (DUF2294)
B2K_RS00620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B2K_RS00625	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B2K_RS00630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B2K_RS00635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B2K_RS00640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B2K_RS00645	COG0137	argininosuccinate synthase activity
B2K_RS00650	COG0165	Argininosuccinate lyase
B2K_RS00655	COG2720	vancomycin resistance protein
B2K_RS00660	COG2884	Cell division ATP-binding protein ftsE
B2K_RS00665	COG2177	Part of the ABC transporter FtsEX involved in
B2K_RS00670	COG0739	heme binding
B2K_RS00675	COG3409	Peptidoglycan-binding domain 1 protein
B2K_RS00675	COG0793	Belongs to the peptidase S41A family
B2K_RS00685	COG1360	Flagellar Motor Protein
B2K_RS00695	COG0556	nucleotide-excision repair
B2K_RS00700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B2K_RS00760	COG0826	peptidase U32
B2K_RS00770	COG1131	(ABC) transporter
B2K_RS00790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B2K_RS00820	COG1403	HNH endonuclease
B2K_RS00830	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
B2K_RS00835	COG0210	DNA helicase
B2K_RS00840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B2K_RS00915	COG2508	Transcriptional regulator
B2K_RS00920	COG3842	ATPase activity
B2K_RS00925	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B2K_RS00930	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B2K_RS00935	COG0546	phosphoglycolate phosphatase activity
B2K_RS00940	COG0110	maltose O-acetyltransferase activity
B2K_RS00945	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B2K_RS00950	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B2K_RS00955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B2K_RS00960	COG0131	Imidazoleglycerol-phosphate dehydratase
B2K_RS00965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B2K_RS00970	COG0107	imidazoleglycerol-phosphate synthase activity
B2K_RS00975	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B2K_RS00975	COG0140	phosphoribosyl-ATP diphosphatase activity
B2K_RS00980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B2K_RS00990	COG0457	Tetratricopeptide repeat
B2K_RS01000	COG3227	Zinc metalloprotease (Elastase)
B2K_RS01010	COG1940	carbohydrate kinase activity
B2K_RS01015	COG1660	Displays ATPase and GTPase activities
B2K_RS01020	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B2K_RS01025	COG1481	regulation of sporulation
B2K_RS01030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2K_RS01045	COG0740	serine-type endopeptidase activity
B2K_RS01060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B2K_RS01065	COG0126	phosphoglycerate kinase activity
B2K_RS01070	COG0149	triose-phosphate isomerase activity
B2K_RS01075	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B2K_RS01080	COG0148	phosphopyruvate hydratase activity
B2K_RS01090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B2K_RS01095	COG2267	carboxylic ester hydrolase activity
B2K_RS01100	COG0557	exoribonuclease II activity
B2K_RS01105	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B2K_RS01130	COG1309	transcriptional regulator
B2K_RS01150	COG0306	phosphate transporter
B2K_RS01155	COG0531	amino acid
B2K_RS01160	COG0583	DNA-binding transcription factor activity
B2K_RS01165	COG2822	iron ion transport
B2K_RS01170	COG2837	iron assimilation
B2K_RS01175	COG0672	)-iron permease
B2K_RS01180	COG1404	Belongs to the peptidase S8 family
B2K_RS01320	COG3711	transcriptional antiterminator
B2K_RS01325	COG2190	(PTS) system
B2K_RS01325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2K_RS01325	COG1263	PTS System
B2K_RS01370	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B2K_RS01375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B2K_RS01385	COG3858	chitin binding
B2K_RS01385	COG1388	LysM domain
B2K_RS01405	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B2K_RS01415	COG0322	excinuclease ABC activity
B2K_RS01420	COG0179	Fumarylacetoacetate (FAA) hydrolase
B2K_RS01435	COG3339	Conserved Protein
B2K_RS01445	COG1278	Cold shock
B2K_RS01470	COG2972	Histidine kinase
B2K_RS01475	COG4753	response regulator
B2K_RS01475	COG2207	Transcriptional regulator
B2K_RS01475	COG4753	response regulator
B2K_RS01475	COG2207	Transcriptional regulator
B2K_RS01480	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS01485	COG4209	transmembrane transport
B2K_RS01490	COG0395	ABC-type sugar transport system, permease component
B2K_RS01495	COG1653	transport
B2K_RS01510	COG4608	Belongs to the ABC transporter superfamily
B2K_RS01515	COG0444	Belongs to the ABC transporter superfamily
B2K_RS01520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2K_RS01525	COG0601	transmembrane transport
B2K_RS01530	COG0747	negative chemotaxis
B2K_RS01545	COG2203	Gaf domain
B2K_RS01545	COG3706	GGDEF domain
B2K_RS01545	COG4251	negative regulation of phosphorylation
B2K_RS01545	COG5001	Diguanylate cyclase
B2K_RS01550	COG0515	serine threonine protein kinase
B2K_RS01580	COG0640	Transcriptional regulator
B2K_RS01585	COG2207	Transcriptional regulator
B2K_RS01590	COG0667	Aldo Keto reductase
B2K_RS01595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B2K_RS01600	COG1309	transcriptional regulator
B2K_RS01605	COG1368	sulfuric ester hydrolase activity
B2K_RS01615	COG3711	transcriptional antiterminator
B2K_RS01625	COG0246	Mannitol dehydrogenase
B2K_RS01635	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B2K_RS01655	COG1802	Transcriptional regulator
B2K_RS01665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS01700	COG1472	Belongs to the glycosyl hydrolase 3 family
B2K_RS01715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B2K_RS01730	COG0745	RESPONSE REGULATOR receiver
B2K_RS01735	COG2197	response regulator
B2K_RS01755	COG0778	Nitroreductase
B2K_RS01760	COG2972	Histidine kinase
B2K_RS01765	COG2207	Transcriptional regulator
B2K_RS01765	COG2207	Transcriptional regulator
B2K_RS01765	COG4753	response regulator
B2K_RS01765	COG4753	response regulator
B2K_RS01770	COG0697	spore germination
B2K_RS01775	COG2814	Major facilitator Superfamily
B2K_RS01815	COG1361	Conserved repeat domain
B2K_RS01840	COG2329	Antibiotic biosynthesis monooxygenase
B2K_RS01845	COG4209	transmembrane transport
B2K_RS01850	COG0395	ABC-type sugar transport system, permease component
B2K_RS01860	COG1501	Belongs to the glycosyl hydrolase 31 family
B2K_RS01870	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS01910	COG1674	ftsk spoiiie
B2K_RS01980	COG3266	domain, Protein
B2K_RS01980	COG2911	Protein conserved in bacteria
B2K_RS01980	COG1361	Conserved repeat domain
B2K_RS01985	COG2911	Protein conserved in bacteria
B2K_RS01985	COG1361	Conserved repeat domain
B2K_RS01985	COG3266	domain, Protein
B2K_RS02025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B2K_RS02030	COG2972	Histidine kinase
B2K_RS02035	COG4753	response regulator
B2K_RS02035	COG2207	Transcriptional regulator
B2K_RS02040	COG2201	protein-glutamate methylesterase activity
B2K_RS02080	COG0861	Integral membrane protein TerC family
B2K_RS02115	COG1595	DNA-templated transcription, initiation
B2K_RS02130	COG0778	Nitroreductase
B2K_RS02145	COG1192	Involved in chromosome partitioning
B2K_RS02160	COG0514	ATP-dependent DNA helicase (RecQ)
B2K_RS02165	COG0328	RNA-DNA hybrid ribonuclease activity
B2K_RS02165	COG3341	Caulimovirus viroplasmin
B2K_RS02170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B2K_RS02175	COG0400	carboxylic ester hydrolase activity
B2K_RS02180	COG0346	lactoylglutathione lyase activity
B2K_RS02185	COG2259	Doxx family
B2K_RS02190	COG1846	Transcriptional regulator
B2K_RS02195	COG2378	regulation of single-species biofilm formation
B2K_RS02200	COG2309	aminopeptidase activity
B2K_RS02205	COG0733	neurotransmitter:sodium symporter activity
B2K_RS02210	COG5001	Diguanylate cyclase
B2K_RS02210	COG3300	MHYT domain
B2K_RS02215	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B2K_RS02225	COG1131	(ABC) transporter
B2K_RS02235	COG5002	protein histidine kinase activity
B2K_RS02235	COG5000	phosphorelay sensor kinase activity
B2K_RS02240	COG0745	RESPONSE REGULATOR receiver
B2K_RS02250	COG4977	sequence-specific DNA binding
B2K_RS02250	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS02265	COG1811	Na channel or pump
B2K_RS02270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B2K_RS02275	COG1132	(ABC) transporter
B2K_RS02280	COG1132	(ABC) transporter
B2K_RS02295	COG1413	lyase activity
B2K_RS02305	COG0194	GDP metabolic process
B2K_RS02340	COG3336	cytochrome c oxidase
B2K_RS02350	COG2226	methyltransferase
B2K_RS02360	COG0741	lytic transglycosylase activity
B2K_RS02360	COG0791	NLP P60 protein
B2K_RS02365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2K_RS02375	COG1733	regulation of RNA biosynthetic process
B2K_RS02390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B2K_RS02415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B2K_RS02420	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS02425	COG0477	Major facilitator Superfamily
B2K_RS02435	COG2081	HI0933 family
B2K_RS02445	COG0840	transmembrane signaling receptor activity
B2K_RS02450	COG1253	flavin adenine dinucleotide binding
B2K_RS02470	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B2K_RS02475	COG3546	catalase activity
B2K_RS02485	COG0736	holo-[acyl-carrier-protein] synthase activity
B2K_RS02500	COG2207	Transcriptional regulator
B2K_RS02510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2K_RS02520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B2K_RS02545	COG3557	Belongs to the UPF0374 family
B2K_RS02575	COG0302	gtp cyclohydrolase
B2K_RS02580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B2K_RS02590	COG1414	Transcriptional regulator
B2K_RS02595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B2K_RS02615	COG4294	response to UV
B2K_RS02625	COG0483	inositol monophosphate 1-phosphatase activity
B2K_RS02715	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B2K_RS02730	COG4106	trans-aconitate 2-methyltransferase activity
B2K_RS02735	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS02740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2K_RS02745	COG0800	Aldolase
B2K_RS02755	COG0070	glutamate synthase
B2K_RS02755	COG0067	glutamate synthase
B2K_RS02755	COG0069	glutamate synthase activity
B2K_RS02760	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B2K_RS02765	COG0384	phenazine biosynthesis protein PhzF
B2K_RS02770	COG1316	TRANSCRIPTIONal
B2K_RS02775	COG4555	ABC transporter
B2K_RS02790	COG2197	response regulator
B2K_RS02795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B2K_RS02800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B2K_RS02805	COG2706	6-phosphogluconolactonase activity
B2K_RS02810	COG0726	polysaccharide deacetylase
B2K_RS02815	COG0714	Associated with various cellular activities
B2K_RS02825	COG1305	Transglutaminase-like
B2K_RS02840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B2K_RS02840	COG0519	Catalyzes the synthesis of GMP from XMP
B2K_RS02845	COG4974	Belongs to the 'phage' integrase family
B2K_RS02885	COG2252	PERMEase
B2K_RS02890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B2K_RS02895	COG2326	polyphosphate kinase activity
B2K_RS02900	COG0488	(ABC) transporter
B2K_RS02905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B2K_RS02910	COG0315	cyclic pyranopterin monophosphate synthase activity
B2K_RS02915	COG0521	Mo-molybdopterin cofactor biosynthetic process
B2K_RS02930	COG0805	protein transport
B2K_RS02935	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B2K_RS02940	COG0459	protein refolding
B2K_RS02950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B2K_RS02985	COG0438	transferase activity, transferring glycosyl groups
B2K_RS02985	COG1216	Glycosyl transferase, family 2
B2K_RS03005	COG0463	Glycosyl transferase, family 2
B2K_RS03020	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B2K_RS03035	COG1091	dTDP-4-dehydrorhamnose reductase activity
B2K_RS03040	COG1216	Glycosyl transferase, family 2
B2K_RS03045	COG1216	Glycosyl transferase, family 2
B2K_RS03050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B2K_RS03055	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B2K_RS03060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B2K_RS03065	COG0864	Transcriptional regulator
B2K_RS03070	COG2337	Toxic component of a toxin-antitoxin (TA) module
B2K_RS03075	COG2183	response to ionizing radiation
B2K_RS03110	COG3871	stress protein (general stress protein 26)
B2K_RS03115	COG3546	catalase activity
B2K_RS03130	COG0584	glycerophosphoryl diester phosphodiesterase
B2K_RS03135	COG1361	Conserved repeat domain
B2K_RS03145	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B2K_RS03150	COG0788	formyltetrahydrofolate deformylase activity
B2K_RS03155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B2K_RS03160	COG2146	nitrite reductase [NAD(P)H] activity
B2K_RS03170	COG3123	guanosine phosphorylase activity
B2K_RS03180	COG0166	Belongs to the GPI family
B2K_RS03185	COG1739	Uncharacterized protein family UPF0029
B2K_RS03190	COG1309	transcriptional regulator
B2K_RS03195	COG0432	Pfam Uncharacterised protein family UPF0047
B2K_RS03210	COG1294	oxidase, subunit
B2K_RS03215	COG1271	oxidase subunit
B2K_RS03295	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B2K_RS03310	COG2201	protein-glutamate methylesterase activity
B2K_RS03315	COG0745	RESPONSE REGULATOR receiver
B2K_RS03320	COG2205	protein histidine kinase activity
B2K_RS03335	COG1486	melibiose metabolic process
B2K_RS03340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B2K_RS03345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B2K_RS03345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B2K_RS03365	COG1051	belongs to the nudix hydrolase family
B2K_RS03375	COG1233	COG1233 Phytoene dehydrogenase and related
B2K_RS03380	COG1846	Transcriptional regulator
B2K_RS03400	COG3401	FG-GAP repeat protein
B2K_RS03410	COG0564	pseudouridine synthase activity
B2K_RS03415	COG3773	Cell wall hydrolase
B2K_RS03445	COG1482	cell wall glycoprotein biosynthetic process
B2K_RS03450	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B2K_RS03460	COG1242	4 iron, 4 sulfur cluster binding
B2K_RS03475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B2K_RS03480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B2K_RS03485	COG0671	phosphoesterase, PA-phosphatase related
B2K_RS03490	COG0438	transferase activity, transferring glycosyl groups
B2K_RS03495	COG1215	transferase activity, transferring glycosyl groups
B2K_RS03505	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B2K_RS03510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B2K_RS03530	COG0028	Belongs to the TPP enzyme family
B2K_RS03535	COG0440	acetolactate synthase activity
B2K_RS03540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B2K_RS03545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B2K_RS03565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS03575	COG0473	3-isopropylmalate dehydrogenase activity
B2K_RS03580	COG0450	alkyl hydroperoxide reductase
B2K_RS03585	COG0509	glycine decarboxylation via glycine cleavage system
B2K_RS03600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B2K_RS03605	COG1543	Belongs to the glycosyl hydrolase 57 family
B2K_RS03625	COG1191	sigma factor activity
B2K_RS03655	COG0667	Aldo Keto reductase
B2K_RS03660	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B2K_RS03670	COG0673	inositol 2-dehydrogenase activity
B2K_RS03675	COG4191	Histidine kinase
B2K_RS03680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B2K_RS03690	COG3547	Transposase (IS116 IS110 IS902 family)
B2K_RS03720	COG0840	transmembrane signaling receptor activity
B2K_RS03755	COG0745	RESPONSE REGULATOR receiver
B2K_RS03790	COG2814	Major facilitator Superfamily
B2K_RS03795	COG2207	Transcriptional regulator
B2K_RS03800	COG2972	Histidine kinase
B2K_RS03805	COG1879	ABC-type sugar transport system periplasmic component
B2K_RS03810	COG2226	methyltransferase
B2K_RS03815	COG0494	nUDIX hydrolase
B2K_RS03825	COG1902	pentaerythritol trinitrate reductase activity
B2K_RS03830	COG1653	transport
B2K_RS03835	COG3275	phosphorelay sensor kinase activity
B2K_RS03840	COG2207	Transcriptional regulator
B2K_RS03840	COG4753	response regulator
B2K_RS03850	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B2K_RS03855	COG1070	Carbohydrate kinase
B2K_RS03865	COG5577	PFAM Coat F domain
B2K_RS03870	COG1063	alcohol dehydrogenase
B2K_RS03880	COG5577	PFAM Coat F domain
B2K_RS03890	COG5577	PFAM Coat F domain
B2K_RS03895	COG1309	transcriptional regulator
B2K_RS03905	COG3540	Alkaline phosphatase
B2K_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS03920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS03925	COG1279	arginine transmembrane transporter activity
B2K_RS03930	COG0243	molybdopterin cofactor binding
B2K_RS03945	COG0531	amino acid
B2K_RS03955	COG3665	Urea carboxylase-associated protein
B2K_RS03960	COG0439	Biotin carboxylase
B2K_RS03975	COG2223	nitrite transmembrane transporter activity
B2K_RS03980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B2K_RS03985	COG0243	molybdopterin cofactor binding
B2K_RS03995	COG1368	sulfuric ester hydrolase activity
B2K_RS04010	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B2K_RS04015	COG4585	Histidine kinase
B2K_RS04020	COG1027	Aspartate ammonia-lyase
B2K_RS04030	COG4191	Histidine kinase
B2K_RS04035	COG0784	Response regulator, receiver
B2K_RS04040	COG3866	Pectate lyase
B2K_RS04060	COG4209	transmembrane transport
B2K_RS04065	COG0395	ABC-type sugar transport system, permease component
B2K_RS04070	COG1653	transport
B2K_RS04075	COG0385	Bile acid
B2K_RS04105	COG0697	spore germination
B2K_RS04115	COG1840	ABC-type Fe3 transport system, periplasmic component
B2K_RS04120	COG3842	ATPase activity
B2K_RS04135	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B2K_RS04145	COG1349	DNA-binding transcription factor activity
B2K_RS04155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B2K_RS04160	COG1360	Flagellar Motor Protein
B2K_RS04250	COG4846	Membrane protein involved in cytochrome C biogenesis
B2K_RS04260	COG1744	ABC transporter substrate-binding protein PnrA-like
B2K_RS04265	COG3845	ABC transporter
B2K_RS04270	COG4603	Belongs to the binding-protein-dependent transport system permease family
B2K_RS04275	COG1079	Belongs to the binding-protein-dependent transport system permease family
B2K_RS04285	COG2226	methyltransferase
B2K_RS04295	COG2814	Major facilitator Superfamily
B2K_RS04305	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B2K_RS04320	COG3069	C4-dicarboxylate transmembrane transporter activity
B2K_RS04325	COG0561	phosphatase activity
B2K_RS04340	COG0737	Belongs to the 5'-nucleotidase family
B2K_RS04345	COG0534	Mate efflux family protein
B2K_RS04355	COG3384	dioxygenase
B2K_RS04390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B2K_RS04400	COG0726	polysaccharide deacetylase
B2K_RS04410	COG0438	transferase activity, transferring glycosyl groups
B2K_RS04425	COG0367	asparagine synthase
B2K_RS04440	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B2K_RS04450	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B2K_RS04455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B2K_RS04470	COG1486	melibiose metabolic process
B2K_RS04495	COG1132	(ABC) transporter
B2K_RS04505	COG0730	response to heat
B2K_RS04510	COG0346	lactoylglutathione lyase activity
B2K_RS04530	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B2K_RS04535	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B2K_RS04550	COG0697	spore germination
B2K_RS04565	COG0583	DNA-binding transcription factor activity
B2K_RS04570	COG0586	Pfam SNARE associated Golgi protein
B2K_RS04580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B2K_RS04600	COG4753	response regulator
B2K_RS04600	COG2207	Transcriptional regulator
B2K_RS04600	COG4753	response regulator
B2K_RS04600	COG2207	Transcriptional regulator
B2K_RS04605	COG5002	protein histidine kinase activity
B2K_RS04610	COG4209	transmembrane transport
B2K_RS04615	COG0395	ABC-type sugar transport system, permease component
B2K_RS04620	COG1653	transport
B2K_RS04635	COG0110	maltose O-acetyltransferase activity
B2K_RS04640	COG1653	transport
B2K_RS04645	COG0395	ABC-type sugar transport system, permease component
B2K_RS04650	COG1175	transmembrane transport
B2K_RS04695	COG0006	proline dipeptidase activity
B2K_RS04705	COG0583	DNA-binding transcription factor activity
B2K_RS04715	COG2200	EAL domain
B2K_RS04720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B2K_RS04725	COG0154	amidase activity
B2K_RS04730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B2K_RS04735	COG0456	acetyltransferase
B2K_RS04735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B2K_RS04745	COG1285	pathogenesis
B2K_RS04770	COG0735	belongs to the Fur family
B2K_RS04790	COG2104	thiamine diphosphate biosynthetic process
B2K_RS04795	COG2022	thiamine diphosphate biosynthetic process
B2K_RS04920	COG0730	response to heat
B2K_RS04925	COG1494	fructose-1,6-bisphosphatase
B2K_RS04930	COG0517	IMP dehydrogenase activity
B2K_RS04940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B2K_RS04945	COG2258	MOSC domain
B2K_RS04950	COG0746	molybdenum cofactor guanylyltransferase activity
B2K_RS04955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B2K_RS04960	COG0303	'Molybdopterin
B2K_RS04965	COG0791	NLP P60 protein
B2K_RS04965	COG0741	lytic transglycosylase activity
B2K_RS04975	COG1595	DNA-templated transcription, initiation
B2K_RS05010	COG1842	Phage shock protein A
B2K_RS05020	COG1842	Phage shock protein A
B2K_RS05025	COG4758	membrane
B2K_RS05030	COG4585	Histidine kinase
B2K_RS05035	COG2197	response regulator
B2K_RS05060	COG5492	domain, Protein
B2K_RS05060	COG4932	domain protein
B2K_RS05070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B2K_RS05075	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B2K_RS05085	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B2K_RS05090	COG0297	glycogen (starch) synthase activity
B2K_RS05105	COG0673	inositol 2-dehydrogenase activity
B2K_RS05125	COG0569	domain protein
B2K_RS05130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B2K_RS05135	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B2K_RS05140	COG2217	Heavy metal translocating P-type atpase
B2K_RS05155	COG0745	RESPONSE REGULATOR receiver
B2K_RS05160	COG5002	protein histidine kinase activity
B2K_RS05180	COG2211	Major facilitator Superfamily
B2K_RS05185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B2K_RS05190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B2K_RS05195	COG1122	ATPase activity
B2K_RS05210	COG0310	cobalt ion transport
B2K_RS05220	COG0601	transmembrane transport
B2K_RS05265	COG1609	Transcriptional regulator
B2K_RS05270	COG2182	Extracellular solute-binding protein
B2K_RS05290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B2K_RS05295	COG4989	oxidoreductase activity
B2K_RS05300	COG0604	alcohol dehydrogenase
B2K_RS05315	COG2197	response regulator
B2K_RS05320	COG0028	Belongs to the TPP enzyme family
B2K_RS05325	COG0440	acetolactate synthase activity
B2K_RS05330	COG0640	Transcriptional regulator
B2K_RS05335	COG0583	DNA-binding transcription factor activity
B2K_RS05350	COG0739	heme binding
B2K_RS05360	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
B2K_RS05365	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
B2K_RS05370	COG1691	(AIR) carboxylase
B2K_RS05375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B2K_RS05380	COG4470	Protein conserved in bacteria
B2K_RS05405	COG3314	Sporulation integral membrane protein YlbJ
B2K_RS05410	COG2346	COG2346, Truncated hemoglobins
B2K_RS05425	COG3093	addiction module antidote protein HigA
B2K_RS05470	COG0701	Predicted permease
B2K_RS05475	COG0180	Tryptophanyl-tRNA synthetase
B2K_RS05490	COG1988	membrane-bound metal-dependent
B2K_RS05500	COG1132	(ABC) transporter
B2K_RS05505	COG1132	(ABC) transporter
B2K_RS05525	COG0395	ABC-type sugar transport system, permease component
B2K_RS05530	COG2723	6-phospho-beta-galactosidase activity
B2K_RS05540	COG2197	response regulator
B2K_RS05545	COG3275	phosphorelay sensor kinase activity
B2K_RS05555	COG2273	Hydrolase Family 16
B2K_RS05605	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
B2K_RS05610	COG2032	superoxide dismutase activity
B2K_RS05615	COG0667	Aldo Keto reductase
B2K_RS05635	COG1227	inorganic diphosphatase activity
B2K_RS05645	COG2116	formate transmembrane transporter activity
B2K_RS05650	COG0039	L-malate dehydrogenase activity
B2K_RS05685	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS05690	COG0656	L-ascorbic acid biosynthetic process
B2K_RS05700	COG0411	ABC transporter
B2K_RS05720	COG0831	urea catabolic process
B2K_RS05725	COG0832	Belongs to the urease beta subunit family
B2K_RS05730	COG0804	urea catabolic process
B2K_RS05735	COG0830	nickel cation binding
B2K_RS05740	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B2K_RS05745	COG0829	nickel cation binding
B2K_RS05750	COG0109	protoheme IX farnesyltransferase activity
B2K_RS05755	COG1999	signal sequence binding
B2K_RS05795	COG0768	penicillin binding
B2K_RS05800	COG0768	penicillin binding
B2K_RS05805	COG0803	Belongs to the bacterial solute-binding protein 9 family
B2K_RS05810	COG1121	(ABC) transporter
B2K_RS05815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B2K_RS05815	COG1321	iron dependent repressor
B2K_RS05820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B2K_RS05830	COG0367	asparagine synthase
B2K_RS05835	COG0561	phosphatase activity
B2K_RS05840	COG2839	Protein conserved in bacteria
B2K_RS05845	COG2244	polysaccharide biosynthetic process
B2K_RS05875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2K_RS05880	COG1612	heme a metabolic process
B2K_RS05895	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS05900	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B2K_RS05910	COG1252	NADH dehydrogenase
B2K_RS05915	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B2K_RS05925	COG0316	Belongs to the HesB IscA family
B2K_RS05945	COG1252	NADH dehydrogenase
B2K_RS05955	COG3858	chitin binding
B2K_RS05960	COG3253	May function as heme-dependent peroxidase
B2K_RS05975	COG1484	DNA-dependent DNA replication
B2K_RS05980	COG3118	belongs to the thioredoxin family
B2K_RS05985	COG0322	excinuclease ABC activity
B2K_RS05995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B2K_RS06000	COG0569	domain protein
B2K_RS06005	COG3263	regulation of cellular component size
B2K_RS06015	COG2009	succinate dehydrogenase
B2K_RS06020	COG1053	succinate dehydrogenase
B2K_RS06025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B2K_RS06030	COG1609	Transcriptional regulator
B2K_RS06075	COG1113	amino acid transport
B2K_RS06080	COG4753	response regulator
B2K_RS06080	COG2207	Transcriptional regulator
B2K_RS06085	COG2972	Histidine kinase
B2K_RS06090	COG4209	transmembrane transport
B2K_RS06095	COG0395	ABC-type sugar transport system, permease component
B2K_RS06110	COG0840	transmembrane signaling receptor activity
B2K_RS06115	COG0673	inositol 2-dehydrogenase activity
B2K_RS06130	COG4209	transmembrane transport
B2K_RS06135	COG0395	ABC-type sugar transport system, permease component
B2K_RS06140	COG1653	transport
B2K_RS06160	COG2357	RelA SpoT domain protein
B2K_RS06170	COG1396	sequence-specific DNA binding
B2K_RS06180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS06185	COG2814	Major facilitator Superfamily
B2K_RS06195	COG1272	protein, Hemolysin III
B2K_RS06205	COG1349	DNA-binding transcription factor activity
B2K_RS06220	COG0395	ABC-type sugar transport system, permease component
B2K_RS06230	COG0584	glycerophosphoryl diester phosphodiesterase
B2K_RS06255	COG1653	transport
B2K_RS06260	COG0395	ABC-type sugar transport system, permease component
B2K_RS06265	COG4209	transmembrane transport
B2K_RS06275	COG0456	acetyltransferase
B2K_RS06280	COG2311	Membrane
B2K_RS06290	COG2801	Transposase and inactivated derivatives
B2K_RS06295	COG2169	Transcriptional regulator
B2K_RS06300	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS06305	COG1595	DNA-templated transcription, initiation
B2K_RS06315	COG0300	oxidoreductase activity
B2K_RS06320	COG0789	Transcriptional regulator
B2K_RS06370	COG2207	Transcriptional regulator
B2K_RS06375	COG4209	transmembrane transport
B2K_RS06380	COG0395	ABC-type sugar transport system, permease component
B2K_RS06385	COG1653	transport
B2K_RS06405	COG0656	L-ascorbic acid biosynthetic process
B2K_RS06410	COG2207	Transcriptional regulator
B2K_RS06415	COG2801	Transposase and inactivated derivatives
B2K_RS06425	COG2207	Transcriptional regulator
B2K_RS06425	COG3708	Transcriptional regulator
B2K_RS06465	COG4209	transmembrane transport
B2K_RS06470	COG0395	ABC-type sugar transport system, permease component
B2K_RS06475	COG1653	transport
B2K_RS06505	COG3214	Protein conserved in bacteria
B2K_RS06525	COG4221	oxidoreductase activity
B2K_RS06540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B2K_RS06545	COG0656	L-ascorbic acid biosynthetic process
B2K_RS06560	COG1733	regulation of RNA biosynthetic process
B2K_RS06565	COG2249	NAD(P)H dehydrogenase (quinone) activity
B2K_RS06570	COG0456	acetyltransferase
B2K_RS06570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B2K_RS06575	COG0667	Aldo Keto reductase
B2K_RS06580	COG0789	Transcriptional regulator
B2K_RS06610	COG0640	Transcriptional regulator
B2K_RS06615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B2K_RS06620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B2K_RS06625	COG0346	lactoylglutathione lyase activity
B2K_RS06635	COG2072	flavoprotein involved in K transport
B2K_RS06640	COG0346	lactoylglutathione lyase activity
B2K_RS06645	COG1846	Transcriptional regulator
B2K_RS06650	COG0577	efflux transmembrane transporter activity
B2K_RS06655	COG1136	(ABC) transporter
B2K_RS06660	COG2205	protein histidine kinase activity
B2K_RS06665	COG0745	RESPONSE REGULATOR receiver
B2K_RS06670	COG2207	Transcriptional regulator
B2K_RS06690	COG2207	Transcriptional regulator
B2K_RS06695	COG1653	transport
B2K_RS06705	COG4978	Transcriptional regulator
B2K_RS06705	COG0789	Transcriptional regulator
B2K_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS06715	COG1349	DNA-binding transcription factor activity
B2K_RS06730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2K_RS06730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2K_RS06730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2K_RS06750	COG2755	lipolytic protein G-D-S-L family
B2K_RS06755	COG1012	belongs to the aldehyde dehydrogenase family
B2K_RS06760	COG1388	LysM domain
B2K_RS06760	COG1705	Flagellar rod assembly protein muramidase FlgJ
B2K_RS06765	COG1653	transport
B2K_RS06785	COG4753	response regulator
B2K_RS06785	COG2207	Transcriptional regulator
B2K_RS06790	COG2972	Histidine kinase
B2K_RS06795	COG1879	ABC-type sugar transport system periplasmic component
B2K_RS06805	COG1172	Belongs to the binding-protein-dependent transport system permease family
B2K_RS06810	COG1172	Belongs to the binding-protein-dependent transport system permease family
B2K_RS06845	COG4977	sequence-specific DNA binding
B2K_RS06845	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS06855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B2K_RS06900	COG2011	ABC-type metal ion transport system permease component
B2K_RS06915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2K_RS06925	COG1309	transcriptional regulator
B2K_RS06930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B2K_RS06930	COG2124	cytochrome p450
B2K_RS06950	COG0673	inositol 2-dehydrogenase activity
B2K_RS06955	COG0667	Aldo Keto reductase
B2K_RS06975	COG0681	Belongs to the peptidase S26 family
B2K_RS06985	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS06995	COG2719	SpoVR family
B2K_RS07000	COG2718	Belongs to the UPF0229 family
B2K_RS07010	COG2502	aspartate--ammonia ligase
B2K_RS07015	COG5002	protein histidine kinase activity
B2K_RS07020	COG4753	response regulator
B2K_RS07020	COG2207	Transcriptional regulator
B2K_RS07025	COG2972	Histidine kinase
B2K_RS07030	COG1653	transport
B2K_RS07035	COG4209	transmembrane transport
B2K_RS07040	COG0395	ABC-type sugar transport system, permease component
B2K_RS07050	COG1404	Belongs to the peptidase S8 family
B2K_RS07050	COG4935	Belongs to the peptidase S8 family
B2K_RS07060	COG4303	Ethanolamine ammonia lyase large subunit
B2K_RS07065	COG4302	ethanolamine ammonia-lyase activity
B2K_RS07070	COG0531	amino acid
B2K_RS07100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B2K_RS07105	COG0765	amino acid transport
B2K_RS07110	COG0765	amino acid transport
B2K_RS07115	COG1126	abc transporter atp-binding protein
B2K_RS07120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2K_RS07135	COG1408	metallophosphoesterase
B2K_RS07255	COG3852	Histidine kinase
B2K_RS07270	COG2363	Small membrane protein
B2K_RS07275	COG3377	Domain of unknown function (DUF1805)
B2K_RS07285	COG0716	FMN binding
B2K_RS07290	COG2186	Transcriptional regulator
B2K_RS07315	COG0402	S-adenosylhomocysteine deaminase activity
B2K_RS07330	COG0714	Associated with various cellular activities
B2K_RS07345	COG1414	Transcriptional regulator
B2K_RS07350	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS07355	COG0179	Fumarylacetoacetate (FAA) hydrolase
B2K_RS07365	COG2721	sulfolactate sulfo-lyase activity
B2K_RS07370	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS07380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B2K_RS07385	COG0363	glucosamine-6-phosphate deaminase activity
B2K_RS07390	COG1737	Transcriptional regulator
B2K_RS07400	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B2K_RS07405	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
B2K_RS07425	COG0396	ATPase activity
B2K_RS07430	COG0719	Fe-S assembly protein
B2K_RS07435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B2K_RS07440	COG0822	iron-sulfur transferase activity
B2K_RS07445	COG0719	Fe-S assembly protein
B2K_RS07450	COG1846	Transcriptional regulator
B2K_RS07455	COG0702	epimerase
B2K_RS07465	COG0789	Transcriptional regulator
B2K_RS07475	COG5002	protein histidine kinase activity
B2K_RS07480	COG0745	RESPONSE REGULATOR receiver
B2K_RS07490	COG2132	Multicopper oxidase
B2K_RS07505	COG2084	Dehydrogenase
B2K_RS07515	COG1733	regulation of RNA biosynthetic process
B2K_RS07520	COG4221	oxidoreductase activity
B2K_RS07530	COG2814	Major facilitator Superfamily
B2K_RS07555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2K_RS07585	COG2199	diguanylate cyclase activity
B2K_RS07585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B2K_RS07590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B2K_RS07595	COG0314	molybdopterin synthase activity
B2K_RS07605	COG0737	Belongs to the 5'-nucleotidase family
B2K_RS07610	COG0535	radical SAM domain protein
B2K_RS07615	COG1253	flavin adenine dinucleotide binding
B2K_RS07620	COG0628	permease
B2K_RS07625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2K_RS07630	COG0791	NLP P60 protein
B2K_RS07630	COG1388	LysM domain
B2K_RS07645	COG3546	catalase activity
B2K_RS07740	COG0582	viral genome integration into host DNA
B2K_RS07775	COG1802	Transcriptional regulator
B2K_RS07775	COG4626	Terminase
B2K_RS07870	COG3409	Peptidoglycan-binding domain 1 protein
B2K_RS07870	COG5632	N-Acetylmuramoyl-L-alanine amidase
B2K_RS07905	COG4974	Belongs to the 'phage' integrase family
B2K_RS07915	COG3547	Transposase (IS116 IS110 IS902 family)
B2K_RS07925	COG1733	regulation of RNA biosynthetic process
B2K_RS07930	COG2249	NAD(P)H dehydrogenase (quinone) activity
B2K_RS07945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS07970	COG3547	Transposase (IS116 IS110 IS902 family)
B2K_RS08035	COG3293	Transposase
B2K_RS08080	COG1733	regulation of RNA biosynthetic process
B2K_RS08085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B2K_RS08090	COG3547	Transposase (IS116 IS110 IS902 family)
B2K_RS08110	COG2076	Multidrug Resistance protein
B2K_RS08115	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B2K_RS08130	COG2205	protein histidine kinase activity
B2K_RS08135	COG0745	RESPONSE REGULATOR receiver
B2K_RS08140	COG3546	catalase activity
B2K_RS08170	COG0189	ligase activity
B2K_RS08175	COG0189	ligase activity
B2K_RS08180	COG0189	ligase activity
B2K_RS08185	COG0189	ligase activity
B2K_RS08195	COG1233	COG1233 Phytoene dehydrogenase and related
B2K_RS08215	COG1349	DNA-binding transcription factor activity
B2K_RS08230	COG4109	DRTGG domain
B2K_RS08250	COG0587	DNA-directed DNA polymerase activity
B2K_RS08255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B2K_RS08265	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B2K_RS08280	COG0824	Thioesterase
B2K_RS08285	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B2K_RS08295	COG0372	Belongs to the citrate synthase family
B2K_RS08300	COG0538	isocitrate dehydrogenase activity
B2K_RS08305	COG0039	L-malate dehydrogenase activity
B2K_RS08320	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
B2K_RS08330	COG0385	Bile acid
B2K_RS08335	COG5002	protein histidine kinase activity
B2K_RS08340	COG0745	RESPONSE REGULATOR receiver
B2K_RS08355	COG0840	transmembrane signaling receptor activity
B2K_RS08360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B2K_RS08365	COG0573	inorganic phosphate transmembrane transporter activity
B2K_RS08370	COG0581	inorganic phosphate transmembrane transporter activity
B2K_RS08375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B2K_RS08380	COG0704	Plays a role in the regulation of phosphate uptake
B2K_RS08390	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B2K_RS08390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B2K_RS08395	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B2K_RS08400	COG1971	Probably functions as a manganese efflux pump
B2K_RS08405	COG0237	dephospho-CoA kinase activity
B2K_RS08420	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B2K_RS08445	COG0640	Transcriptional regulator
B2K_RS08450	COG1309	transcriptional regulator
B2K_RS08475	COG0604	alcohol dehydrogenase
B2K_RS08490	COG0454	-acetyltransferase
B2K_RS08490	COG0456	acetyltransferase
B2K_RS08495	COG2207	Transcriptional regulator
B2K_RS08495	COG4753	response regulator
B2K_RS08500	COG2972	Histidine kinase
B2K_RS08510	COG1175	transmembrane transport
B2K_RS08515	COG3833	ABC-type maltose transport systems, permease component
B2K_RS08525	COG0574	Belongs to the PEP-utilizing enzyme family
B2K_RS08525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B2K_RS08545	COG1937	Protein conserved in bacteria
B2K_RS08550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B2K_RS08555	COG0425	Belongs to the sulfur carrier protein TusA family
B2K_RS08560	COG2210	Belongs to the sulfur carrier protein TusA family
B2K_RS08565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B2K_RS08565	COG0425	Belongs to the sulfur carrier protein TusA family
B2K_RS08570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B2K_RS08570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B2K_RS08595	COG0494	nUDIX hydrolase
B2K_RS08610	COG0477	Major facilitator Superfamily
B2K_RS08625	COG2085	NADP oxidoreductase coenzyme F420-dependent
B2K_RS08630	COG3547	Transposase (IS116 IS110 IS902 family)
B2K_RS08640	COG0596	Alpha beta hydrolase
B2K_RS08650	COG2378	regulation of single-species biofilm formation
B2K_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS08675	COG2085	NADP oxidoreductase coenzyme F420-dependent
B2K_RS08685	COG1309	transcriptional regulator
B2K_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS08695	COG0300	oxidoreductase activity
B2K_RS08700	COG1063	alcohol dehydrogenase
B2K_RS08720	COG2226	methyltransferase
B2K_RS08735	COG4585	Histidine kinase
B2K_RS08740	COG2197	response regulator
B2K_RS08765	COG1472	Belongs to the glycosyl hydrolase 3 family
B2K_RS08790	COG4209	transmembrane transport
B2K_RS08795	COG0395	ABC-type sugar transport system, permease component
B2K_RS08800	COG2207	Transcriptional regulator
B2K_RS08825	COG4753	response regulator
B2K_RS08825	COG2207	Transcriptional regulator
B2K_RS08840	COG1175	transmembrane transport
B2K_RS08880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B2K_RS08905	COG0243	molybdopterin cofactor binding
B2K_RS08950	COG1151	hydroxylamine reductase activity
B2K_RS08955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2K_RS08965	COG2197	response regulator
B2K_RS08970	COG4585	Histidine kinase
B2K_RS08990	COG1012	belongs to the aldehyde dehydrogenase family
B2K_RS08990	COG1454	alcohol dehydrogenase
B2K_RS08995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B2K_RS09005	COG0746	molybdenum cofactor guanylyltransferase activity
B2K_RS09010	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B2K_RS09010	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B2K_RS09020	COG0791	NLP P60 protein
B2K_RS09035	COG2986	histidine ammonia-lyase
B2K_RS09040	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B2K_RS09045	COG1228	amidohydrolase
B2K_RS09055	COG0402	S-adenosylhomocysteine deaminase activity
B2K_RS09060	COG1874	Beta-galactosidase
B2K_RS09060	COG0366	Alpha amylase catalytic
B2K_RS09070	COG0697	spore germination
B2K_RS09095	COG3845	ABC transporter
B2K_RS09105	COG1079	Belongs to the binding-protein-dependent transport system permease family
B2K_RS09120	COG1609	Transcriptional regulator
B2K_RS09125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2K_RS09160	COG5002	protein histidine kinase activity
B2K_RS09165	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS09185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B2K_RS09205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B2K_RS09215	COG2720	vancomycin resistance protein
B2K_RS09230	COG0523	cobalamin synthesis protein
B2K_RS09235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B2K_RS09240	COG0390	transport system, permease component
B2K_RS09245	COG2318	DinB family
B2K_RS09265	COG1069	ribulokinase activity
B2K_RS09305	COG1846	Transcriptional regulator
B2K_RS09315	COG1940	carbohydrate kinase activity
B2K_RS09350	COG0352	thiamine-phosphate diphosphorylase activity
B2K_RS09355	COG0351	phosphomethylpyrimidine kinase
B2K_RS09385	COG0242	peptide deformylase activity
B2K_RS09400	COG0745	RESPONSE REGULATOR receiver
B2K_RS09405	COG5002	protein histidine kinase activity
B2K_RS09410	COG0800	Aldolase
B2K_RS09425	COG0129	dihydroxy-acid dehydratase activity
B2K_RS09495	COG0662	Cupin 2, conserved barrel domain protein
B2K_RS09495	COG2207	Transcriptional regulator
B2K_RS09500	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B2K_RS09505	COG1486	melibiose metabolic process
B2K_RS09515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B2K_RS09525	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
B2K_RS09530	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS09530	COG2169	Transcriptional regulator
B2K_RS09540	COG0628	permease
B2K_RS09545	COG1733	regulation of RNA biosynthetic process
B2K_RS09550	COG0316	Belongs to the HesB IscA family
B2K_RS09555	COG4844	belongs to the
B2K_RS09575	COG0116	Belongs to the methyltransferase superfamily
B2K_RS09580	COG4122	O-methyltransferase activity
B2K_RS09585	COG2318	DinB family
B2K_RS09600	COG2843	Capsule synthesis protein
B2K_RS09605	COG0179	Fumarylacetoacetate (FAA) hydrolase
B2K_RS09620	COG5416	Lipopolysaccharide assembly protein A domain
B2K_RS09625	COG1164	Oligoendopeptidase f
B2K_RS09635	COG0861	Integral membrane protein TerC family
B2K_RS09660	COG0659	secondary active sulfate transmembrane transporter activity
B2K_RS09670	COG0577	efflux transmembrane transporter activity
B2K_RS09675	COG1136	(ABC) transporter
B2K_RS09680	COG2814	Major facilitator Superfamily
B2K_RS09715	COG0431	NADPH-dependent FMN reductase
B2K_RS09720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B2K_RS09740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B2K_RS09765	COG0513	Belongs to the DEAD box helicase family
B2K_RS09770	COG5578	integral membrane protein
B2K_RS09775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B2K_RS09780	COG1070	Carbohydrate kinase
B2K_RS09795	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B2K_RS09800	COG0583	DNA-binding transcription factor activity
B2K_RS09805	COG4533	DNA binding
B2K_RS09810	COG2738	Putative neutral zinc metallopeptidase
B2K_RS09815	COG0789	Transcriptional regulator
B2K_RS09820	COG0004	ammonium transporteR
B2K_RS09830	COG2176	DNA-directed DNA polymerase activity
B2K_RS09840	COG2814	Major facilitator Superfamily
B2K_RS09845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2K_RS09850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B2K_RS09855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B2K_RS09860	COG1763	Mo-molybdopterin cofactor biosynthetic process
B2K_RS09865	COG1141	Ferredoxin
B2K_RS09885	COG0167	dihydroorotate dehydrogenase activity
B2K_RS09890	COG2357	RelA SpoT domain protein
B2K_RS09895	COG1547	Domain of unknown function (DUF309)
B2K_RS09900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2K_RS09905	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
B2K_RS09905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B2K_RS09910	COG1187	pseudouridine synthase activity
B2K_RS09915	COG0561	phosphatase activity
B2K_RS09925	COG3237	CsbD-like
B2K_RS09930	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B2K_RS09930	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
B2K_RS09935	COG0720	synthase
B2K_RS09940	COG0602	queuosine metabolic process
B2K_RS09945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B2K_RS09955	COG2746	aminoglycoside 3-N-acetyltransferase activity
B2K_RS09960	COG3706	GGDEF domain
B2K_RS09965	COG0438	transferase activity, transferring glycosyl groups
B2K_RS09985	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS10000	COG3949	Membrane
B2K_RS10005	COG0586	Pfam SNARE associated Golgi protein
B2K_RS10015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B2K_RS10055	COG1316	TRANSCRIPTIONal
B2K_RS10080	COG0018	arginyl-trna synthetase
B2K_RS10095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B2K_RS10110	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B2K_RS10115	COG0095	Lipoate-protein ligase
B2K_RS10145	COG1653	transport
B2K_RS10150	COG4209	transmembrane transport
B2K_RS10155	COG0395	ABC-type sugar transport system, permease component
B2K_RS10160	COG3250	beta-galactosidase activity
B2K_RS10170	COG0667	Aldo Keto reductase
B2K_RS10215	COG0252	asparaginase activity
B2K_RS10225	COG1027	Aspartate ammonia-lyase
B2K_RS10280	COG1733	regulation of RNA biosynthetic process
B2K_RS10285	COG2249	NAD(P)H dehydrogenase (quinone) activity
B2K_RS10330	COG4753	response regulator
B2K_RS10330	COG2207	Transcriptional regulator
B2K_RS10335	COG2972	Histidine kinase
B2K_RS10350	COG3119	arylsulfatase activity
B2K_RS10355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B2K_RS10360	COG2207	Transcriptional regulator
B2K_RS10380	COG1175	transmembrane transport
B2K_RS10385	COG0395	ABC-type sugar transport system, permease component
B2K_RS10405	COG2182	Extracellular solute-binding protein
B2K_RS10430	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B2K_RS10435	COG2972	Histidine kinase
B2K_RS10455	COG4209	transmembrane transport
B2K_RS10460	COG0395	ABC-type sugar transport system, permease component
B2K_RS10475	COG2207	Transcriptional regulator
B2K_RS10475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B2K_RS10515	COG0789	Transcriptional regulator
B2K_RS10540	COG3293	Transposase
B2K_RS10575	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS10575	COG2169	Transcriptional regulator
B2K_RS10580	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS10580	COG2207	Transcriptional regulator
B2K_RS10590	COG2207	Transcriptional regulator
B2K_RS10595	COG0667	Aldo Keto reductase
B2K_RS10605	COG3250	beta-galactosidase activity
B2K_RS10610	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS10645	COG2207	Transcriptional regulator
B2K_RS10650	COG3275	phosphorelay sensor kinase activity
B2K_RS10655	COG4209	transmembrane transport
B2K_RS10660	COG0395	ABC-type sugar transport system, permease component
B2K_RS10695	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B2K_RS10705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B2K_RS10710	COG3292	Two component regulator propeller
B2K_RS10710	COG2205	protein histidine kinase activity
B2K_RS10710	COG0745	RESPONSE REGULATOR receiver
B2K_RS10715	COG0673	inositol 2-dehydrogenase activity
B2K_RS10725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2K_RS10740	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS10740	COG4977	sequence-specific DNA binding
B2K_RS10745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2K_RS10755	COG2203	Gaf domain
B2K_RS10755	COG3706	GGDEF domain
B2K_RS10755	COG4251	negative regulation of phosphorylation
B2K_RS10755	COG5001	Diguanylate cyclase
B2K_RS10785	COG1653	transport
B2K_RS10790	COG0395	ABC-type sugar transport system, permease component
B2K_RS10795	COG4209	transmembrane transport
B2K_RS10800	COG2207	Transcriptional regulator
B2K_RS10835	COG2207	Transcriptional regulator
B2K_RS10840	COG4209	transmembrane transport
B2K_RS10845	COG0395	ABC-type sugar transport system, permease component
B2K_RS10850	COG1653	transport
B2K_RS10865	COG0445	tRNA wobble uridine modification
B2K_RS10875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B2K_RS10880	COG1929	Belongs to the glycerate kinase type-1 family
B2K_RS10905	COG4753	response regulator
B2K_RS10905	COG2207	Transcriptional regulator
B2K_RS10910	COG0583	DNA-binding transcription factor activity
B2K_RS10915	COG0583	DNA-binding transcription factor activity
B2K_RS10930	COG2207	Transcriptional regulator
B2K_RS10930	COG4753	response regulator
B2K_RS10935	COG0583	DNA-binding transcription factor activity
B2K_RS10940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B2K_RS10955	COG2972	Histidine kinase
B2K_RS10960	COG2207	Transcriptional regulator
B2K_RS10965	COG1653	transport
B2K_RS10970	COG4209	transmembrane transport
B2K_RS10975	COG0395	ABC-type sugar transport system, permease component
B2K_RS11005	COG3250	beta-galactosidase activity
B2K_RS11020	COG0789	Transcriptional regulator
B2K_RS11030	COG4221	oxidoreductase activity
B2K_RS11035	COG2207	Transcriptional regulator
B2K_RS11045	COG0346	lactoylglutathione lyase activity
B2K_RS11080	COG2244	polysaccharide biosynthetic process
B2K_RS11085	COG0250	Participates in transcription elongation, termination and antitermination
B2K_RS11095	COG2070	2-Nitropropane dioxygenase
B2K_RS11095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B2K_RS11100	COG0300	oxidoreductase activity
B2K_RS11100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B2K_RS11100	COG3321	synthase
B2K_RS11100	COG4221	oxidoreductase activity
B2K_RS11105	COG3321	synthase
B2K_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS11105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B2K_RS11105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B2K_RS11105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B2K_RS11110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B2K_RS11110	COG3321	synthase
B2K_RS11110	COG3321	synthase
B2K_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS11110	COG4221	oxidoreductase activity
B2K_RS11110	COG4221	oxidoreductase activity
B2K_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS11110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B2K_RS11130	COG1609	Transcriptional regulator
B2K_RS11135	COG4209	transmembrane transport
B2K_RS11140	COG0395	ABC-type sugar transport system, permease component
B2K_RS11150	COG1621	beta-fructofuranosidase activity
B2K_RS11155	COG1621	beta-fructofuranosidase activity
B2K_RS11170	COG5297	Belongs to the glycosyl hydrolase family 6
B2K_RS11170	COG4733	cellulase activity
B2K_RS11185	COG1063	alcohol dehydrogenase
B2K_RS11215	COG0747	negative chemotaxis
B2K_RS11225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2K_RS11230	COG0444	Belongs to the ABC transporter superfamily
B2K_RS11235	COG1124	(ABC) transporter
B2K_RS11260	COG0583	DNA-binding transcription factor activity
B2K_RS11275	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS11280	COG0666	response to abiotic stimulus
B2K_RS11290	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS11305	COG1942	4-Oxalocrotonate Tautomerase
B2K_RS11310	COG1349	DNA-binding transcription factor activity
B2K_RS11315	COG3718	enzyme involved in inositol metabolism
B2K_RS11325	COG0191	fructose-bisphosphate aldolase activity
B2K_RS11330	COG1349	DNA-binding transcription factor activity
B2K_RS11350	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B2K_RS11365	COG0583	DNA-binding transcription factor activity
B2K_RS11370	COG0384	phenazine biosynthesis protein PhzF
B2K_RS11400	COG1733	regulation of RNA biosynthetic process
B2K_RS11420	COG0504	CTP synthase activity
B2K_RS11430	COG1653	transport
B2K_RS11440	COG2207	Transcriptional regulator
B2K_RS11440	COG4753	response regulator
B2K_RS11445	COG1621	beta-fructofuranosidase activity
B2K_RS11450	COG1175	transmembrane transport
B2K_RS11455	COG0395	ABC-type sugar transport system, permease component
B2K_RS11485	COG1309	transcriptional regulator
B2K_RS11490	COG2076	Multidrug Resistance protein
B2K_RS11495	COG2076	Multidrug Resistance protein
B2K_RS11505	COG2814	Major facilitator Superfamily
B2K_RS11520	COG4209	transmembrane transport
B2K_RS11525	COG0395	ABC-type sugar transport system, permease component
B2K_RS11530	COG1653	transport
B2K_RS11535	COG2207	Transcriptional regulator
B2K_RS11545	COG1309	transcriptional regulator
B2K_RS11560	COG2755	lipolytic protein G-D-S-L family
B2K_RS11565	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B2K_RS11570	COG2207	Transcriptional regulator
B2K_RS11575	COG4209	transmembrane transport
B2K_RS11580	COG0395	ABC-type sugar transport system, permease component
B2K_RS11585	COG1653	transport
B2K_RS11595	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B2K_RS11600	COG2207	Transcriptional regulator
B2K_RS11600	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS11620	COG1879	ABC-type sugar transport system periplasmic component
B2K_RS11625	COG1129	ABC transporter
B2K_RS11630	COG1172	Belongs to the binding-protein-dependent transport system permease family
B2K_RS11635	COG1609	Transcriptional regulator
B2K_RS11645	COG4209	transmembrane transport
B2K_RS11650	COG0395	ABC-type sugar transport system, permease component
B2K_RS11660	COG1621	beta-fructofuranosidase activity
B2K_RS11670	COG1335	isochorismatase
B2K_RS11690	COG2814	Major facilitator Superfamily
B2K_RS11695	COG0783	Belongs to the Dps family
B2K_RS11705	COG0346	lactoylglutathione lyase activity
B2K_RS11710	COG0400	carboxylic ester hydrolase activity
B2K_RS11780	COG3547	Transposase (IS116 IS110 IS902 family)
B2K_RS11800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B2K_RS11805	COG1522	sequence-specific DNA binding
B2K_RS11810	COG0477	Major facilitator Superfamily
B2K_RS11815	COG0640	Transcriptional regulator
B2K_RS11820	COG2814	Major facilitator Superfamily
B2K_RS11825	COG4209	transmembrane transport
B2K_RS11830	COG0395	ABC-type sugar transport system, permease component
B2K_RS11835	COG1653	transport
B2K_RS11850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS11855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS11870	COG3401	FG-GAP repeat protein
B2K_RS11880	COG1063	alcohol dehydrogenase
B2K_RS11885	COG2211	Major facilitator Superfamily
B2K_RS11895	COG0697	spore germination
B2K_RS11910	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B2K_RS11940	COG2207	Transcriptional regulator
B2K_RS11945	COG1653	transport
B2K_RS11950	COG4209	transmembrane transport
B2K_RS11955	COG0395	ABC-type sugar transport system, permease component
B2K_RS11960	COG3250	beta-galactosidase activity
B2K_RS11965	COG1802	Transcriptional regulator
B2K_RS11970	COG1312	Catalyzes the dehydration of D-mannonate
B2K_RS11975	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS12005	COG1175	transmembrane transport
B2K_RS12010	COG0395	ABC-type sugar transport system, permease component
B2K_RS12015	COG2972	Histidine kinase
B2K_RS12025	COG4753	response regulator
B2K_RS12025	COG2207	Transcriptional regulator
B2K_RS12025	COG2207	Transcriptional regulator
B2K_RS12025	COG4753	response regulator
B2K_RS12030	COG1063	alcohol dehydrogenase
B2K_RS12040	COG1793	dna ligase
B2K_RS12050	COG2910	NAD(P)H-binding
B2K_RS12055	COG0109	protoheme IX farnesyltransferase activity
B2K_RS12070	COG0179	Fumarylacetoacetate (FAA) hydrolase
B2K_RS12080	COG0129	dihydroxy-acid dehydratase activity
B2K_RS12085	COG0579	oxidoreductase
B2K_RS12110	COG2249	NAD(P)H dehydrogenase (quinone) activity
B2K_RS12125	COG3250	beta-galactosidase activity
B2K_RS12135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B2K_RS12160	COG1175	transmembrane transport
B2K_RS12165	COG0395	ABC-type sugar transport system, permease component
B2K_RS12180	COG2972	Histidine kinase
B2K_RS12185	COG4753	response regulator
B2K_RS12185	COG2207	Transcriptional regulator
B2K_RS12200	COG0662	Cupin 2, conserved barrel domain protein
B2K_RS12205	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
B2K_RS12225	COG0745	RESPONSE REGULATOR receiver
B2K_RS12230	COG1874	Beta-galactosidase
B2K_RS12230	COG0366	Alpha amylase catalytic
B2K_RS12235	COG3706	GGDEF domain
B2K_RS12235	COG4251	negative regulation of phosphorylation
B2K_RS12235	COG2203	Gaf domain
B2K_RS12235	COG5001	Diguanylate cyclase
B2K_RS12250	COG1653	transport
B2K_RS12255	COG0840	transmembrane signaling receptor activity
B2K_RS12260	COG2972	Histidine kinase
B2K_RS12265	COG4565	transcriptional regulatory protein
B2K_RS12275	COG0366	Alpha amylase catalytic
B2K_RS12285	COG1175	transmembrane transport
B2K_RS12290	COG0395	ABC-type sugar transport system, permease component
B2K_RS12310	COG2972	Histidine kinase
B2K_RS12315	COG2201	protein-glutamate methylesterase activity
B2K_RS12320	COG1175	transmembrane transport
B2K_RS12325	COG0395	ABC-type sugar transport system, permease component
B2K_RS12355	COG0697	spore germination
B2K_RS12360	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B2K_RS12365	COG2318	DinB family
B2K_RS12395	COG2972	Histidine kinase
B2K_RS12400	COG4753	response regulator
B2K_RS12400	COG2207	Transcriptional regulator
B2K_RS12430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B2K_RS12435	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B2K_RS12440	COG1175	transmembrane transport
B2K_RS12445	COG0395	ABC-type sugar transport system, permease component
B2K_RS12455	COG3118	belongs to the thioredoxin family
B2K_RS12465	COG0477	Major facilitator Superfamily
B2K_RS12480	COG0523	cobalamin synthesis protein
B2K_RS12490	COG0154	amidase activity
B2K_RS12495	COG5001	Diguanylate cyclase
B2K_RS12495	COG3300	MHYT domain
B2K_RS12510	COG4209	transmembrane transport
B2K_RS12515	COG0395	ABC-type sugar transport system, permease component
B2K_RS12525	COG1874	Beta-galactosidase
B2K_RS12530	COG1846	Transcriptional regulator
B2K_RS12540	COG2259	Doxx family
B2K_RS12545	COG2972	Histidine kinase
B2K_RS12550	COG4753	response regulator
B2K_RS12550	COG2207	Transcriptional regulator
B2K_RS12560	COG4209	transmembrane transport
B2K_RS12565	COG0395	ABC-type sugar transport system, permease component
B2K_RS12575	COG2972	Histidine kinase
B2K_RS12615	COG0708	Exodeoxyribonuclease III
B2K_RS12625	COG4209	transmembrane transport
B2K_RS12630	COG0395	ABC-type sugar transport system, permease component
B2K_RS12635	COG2972	Histidine kinase
B2K_RS12640	COG4753	response regulator
B2K_RS12640	COG2207	Transcriptional regulator
B2K_RS12665	COG2205	protein histidine kinase activity
B2K_RS12685	COG1510	regulation of RNA biosynthetic process
B2K_RS12690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B2K_RS12710	COG3250	beta-galactosidase activity
B2K_RS12720	COG2972	Histidine kinase
B2K_RS12725	COG2207	Transcriptional regulator
B2K_RS12725	COG4753	response regulator
B2K_RS12730	COG4753	response regulator
B2K_RS12730	COG2207	Transcriptional regulator
B2K_RS12735	COG4209	transmembrane transport
B2K_RS12740	COG0395	ABC-type sugar transport system, permease component
B2K_RS12770	COG0395	ABC-type sugar transport system, permease component
B2K_RS12815	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS12815	COG2207	Transcriptional regulator
B2K_RS12825	COG1175	transmembrane transport
B2K_RS12830	COG0395	ABC-type sugar transport system, permease component
B2K_RS12845	COG2972	Histidine kinase
B2K_RS12850	COG2207	Transcriptional regulator
B2K_RS12850	COG4753	response regulator
B2K_RS12860	COG1175	transmembrane transport
B2K_RS12865	COG0395	ABC-type sugar transport system, permease component
B2K_RS12870	COG3250	beta-galactosidase activity
B2K_RS12880	COG4585	Histidine kinase
B2K_RS12885	COG2197	response regulator
B2K_RS12900	COG0583	DNA-binding transcription factor activity
B2K_RS12925	COG1278	Cold shock
B2K_RS12945	COG4977	sequence-specific DNA binding
B2K_RS12955	COG1653	transport
B2K_RS12960	COG1175	transmembrane transport
B2K_RS12965	COG0395	ABC-type sugar transport system, permease component
B2K_RS13015	COG1280	lysine exporter protein (LysE YggA)
B2K_RS13025	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B2K_RS13035	COG3622	Belongs to the hyi family
B2K_RS13040	COG0488	(ABC) transporter
B2K_RS13050	COG0697	spore germination
B2K_RS13055	COG0789	Transcriptional regulator
B2K_RS13060	COG0534	Mate efflux family protein
B2K_RS13075	COG0667	Aldo Keto reductase
B2K_RS13085	COG2755	lipolytic protein G-D-S-L family
B2K_RS13090	COG2197	response regulator
B2K_RS13105	COG0745	RESPONSE REGULATOR receiver
B2K_RS13110	COG2205	protein histidine kinase activity
B2K_RS13125	COG1968	undecaprenyl-diphosphatase activity
B2K_RS13145	COG0640	Transcriptional regulator
B2K_RS13155	COG1309	transcriptional regulator
B2K_RS13175	COG3507	Belongs to the glycosyl hydrolase 43 family
B2K_RS13180	COG2318	DinB family
B2K_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS13255	COG0604	alcohol dehydrogenase
B2K_RS13255	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS13255	COG3321	synthase
B2K_RS13260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B2K_RS13275	COG1164	Oligoendopeptidase f
B2K_RS13280	COG0318	PFAM AMP-dependent synthetase and ligase
B2K_RS13290	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS13320	COG4565	transcriptional regulatory protein
B2K_RS13325	COG3290	protein histidine kinase activity
B2K_RS13330	COG1234	tRNA 3'-trailer cleavage
B2K_RS13340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS13345	COG0697	spore germination
B2K_RS13355	COG2207	Transcriptional regulator
B2K_RS13360	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS13395	COG0456	acetyltransferase
B2K_RS13410	COG2132	Multicopper oxidase
B2K_RS13435	COG2367	Beta-lactamase
B2K_RS13455	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS13480	COG0789	Transcriptional regulator
B2K_RS13485	COG4221	oxidoreductase activity
B2K_RS13545	COG2404	hydrolase activity, acting on ester bonds
B2K_RS13555	COG2814	Major facilitator Superfamily
B2K_RS13560	COG4565	transcriptional regulatory protein
B2K_RS13565	COG3290	protein histidine kinase activity
B2K_RS13575	COG2851	Citrate transporter
B2K_RS13580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B2K_RS13585	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B2K_RS13590	COG0488	(ABC) transporter
B2K_RS13615	COG2972	Histidine kinase
B2K_RS13620	COG4753	response regulator
B2K_RS13620	COG2207	Transcriptional regulator
B2K_RS13630	COG1175	transmembrane transport
B2K_RS13635	COG0395	ABC-type sugar transport system, permease component
B2K_RS13650	COG3300	MHYT domain
B2K_RS13650	COG5001	Diguanylate cyclase
B2K_RS13655	COG0028	Belongs to the TPP enzyme family
B2K_RS13670	COG0028	Belongs to the TPP enzyme family
B2K_RS13675	COG5002	protein histidine kinase activity
B2K_RS13680	COG1116	anion transmembrane transporter activity
B2K_RS13685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS13690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS13695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B2K_RS13700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B2K_RS13715	COG0493	'glutamate synthase
B2K_RS13715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B2K_RS13720	COG0167	dihydroorotate dehydrogenase activity
B2K_RS13735	COG3835	regulator
B2K_RS13740	COG1012	belongs to the aldehyde dehydrogenase family
B2K_RS13750	COG0840	transmembrane signaling receptor activity
B2K_RS13755	COG1695	Transcriptional regulator
B2K_RS13785	COG3507	Belongs to the glycosyl hydrolase 43 family
B2K_RS13795	COG2226	methyltransferase
B2K_RS13800	COG4209	transmembrane transport
B2K_RS13805	COG0395	ABC-type sugar transport system, permease component
B2K_RS13815	COG4753	response regulator
B2K_RS13815	COG2207	Transcriptional regulator
B2K_RS13815	COG2207	Transcriptional regulator
B2K_RS13815	COG4753	response regulator
B2K_RS13820	COG2972	Histidine kinase
B2K_RS13825	COG0583	DNA-binding transcription factor activity
B2K_RS13830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B2K_RS13865	COG1131	(ABC) transporter
B2K_RS13875	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B2K_RS13895	COG1741	Belongs to the pirin family
B2K_RS13905	COG1794	racemase activity, acting on amino acids and derivatives
B2K_RS13910	COG0697	spore germination
B2K_RS13915	COG0531	amino acid
B2K_RS13930	COG0840	transmembrane signaling receptor activity
B2K_RS13940	COG2017	converts alpha-aldose to the beta-anomer
B2K_RS13960	COG0840	transmembrane signaling receptor activity
B2K_RS13975	COG0740	serine-type endopeptidase activity
B2K_RS14000	COG0586	Pfam SNARE associated Golgi protein
B2K_RS14010	COG5002	protein histidine kinase activity
B2K_RS14045	COG2723	6-phospho-beta-galactosidase activity
B2K_RS14050	COG1609	Transcriptional regulator
B2K_RS14075	COG1742	UPF0060 membrane protein
B2K_RS14090	COG4213	ABC transporter substrate-binding protein
B2K_RS14095	COG0840	transmembrane signaling receptor activity
B2K_RS14100	COG3300	MHYT domain
B2K_RS14100	COG5001	Diguanylate cyclase
B2K_RS14105	COG1609	Transcriptional regulator
B2K_RS14110	COG0673	inositol 2-dehydrogenase activity
B2K_RS14115	COG2201	protein-glutamate methylesterase activity
B2K_RS14120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B2K_RS14135	COG1132	(ABC) transporter
B2K_RS14140	COG1132	(ABC) transporter
B2K_RS14150	COG1368	sulfuric ester hydrolase activity
B2K_RS14160	COG0745	RESPONSE REGULATOR receiver
B2K_RS14165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B2K_RS14170	COG0105	UTP biosynthetic process
B2K_RS14185	COG2309	aminopeptidase activity
B2K_RS14195	COG2169	Transcriptional regulator
B2K_RS14200	COG0673	inositol 2-dehydrogenase activity
B2K_RS14210	COG0583	DNA-binding transcription factor activity
B2K_RS14215	COG2610	gluconate transmembrane transporter activity
B2K_RS14220	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS14225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B2K_RS14230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B2K_RS14240	COG2124	cytochrome p450
B2K_RS14245	COG3344	reverse transcriptase
B2K_RS14250	COG2252	PERMEase
B2K_RS14255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B2K_RS14260	COG2207	Transcriptional regulator
B2K_RS14280	COG2814	Major facilitator Superfamily
B2K_RS14290	COG3639	organic phosphonate transmembrane transporter activity
B2K_RS14295	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B2K_RS14300	COG0709	Synthesizes selenophosphate from selenide and ATP
B2K_RS14305	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
B2K_RS14310	COG1733	regulation of RNA biosynthetic process
B2K_RS14315	COG1012	belongs to the aldehyde dehydrogenase family
B2K_RS14320	COG4876	unkown
B2K_RS14325	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS14335	COG1136	(ABC) transporter
B2K_RS14340	COG1136	(ABC) transporter
B2K_RS14340	COG0577	efflux transmembrane transporter activity
B2K_RS14355	COG1733	regulation of RNA biosynthetic process
B2K_RS14365	COG4120	Belongs to the binding-protein-dependent transport system permease family
B2K_RS14370	COG1116	anion transmembrane transporter activity
B2K_RS14370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B2K_RS14395	COG0454	-acetyltransferase
B2K_RS14415	COG1077	Cell shape determining protein MreB Mrl
B2K_RS14430	COG2205	protein histidine kinase activity
B2K_RS14450	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B2K_RS14475	COG1121	(ABC) transporter
B2K_RS14480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B2K_RS14485	COG0785	Cytochrome C biogenesis protein
B2K_RS14490	COG1533	DNA photolyase activity
B2K_RS14500	COG1752	Esterase of the alpha-beta hydrolase superfamily
B2K_RS14510	COG3872	metal-dependent enzyme
B2K_RS14520	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B2K_RS14525	COG0006	proline dipeptidase activity
B2K_RS14530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B2K_RS14540	COG4109	DRTGG domain
B2K_RS14575	COG2707	UPF0756 membrane protein
B2K_RS14580	COG2045	Belongs to the ComB family
B2K_RS14585	COG1809	phosphosulfolactate synthase activity
B2K_RS14595	COG3854	ATPases associated with a variety of cellular activities
B2K_RS14635	COG0511	ligase activity, forming carbon-carbon bonds
B2K_RS14640	COG0439	Biotin carboxylase
B2K_RS14650	COG1302	Protein conserved in bacteria
B2K_RS14665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B2K_RS14670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B2K_RS14675	COG1570	exodeoxyribonuclease VII activity
B2K_RS14680	COG1722	exodeoxyribonuclease VII activity
B2K_RS14690	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B2K_RS14695	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B2K_RS14705	COG1438	arginine binding
B2K_RS14710	COG0497	DNA recombination
B2K_RS14715	COG0750	zinc metalloprotease
B2K_RS14720	COG0745	RESPONSE REGULATOR receiver
B2K_RS14740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B2K_RS14750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B2K_RS14755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B2K_RS14760	COG0022	dehydrogenase e1 component
B2K_RS14765	COG0508	dehydrogenase complex catalyzes the overall conversion of
B2K_RS14770	COG2195	Cleaves the N-terminal amino acid of tripeptides
B2K_RS14785	COG1379	DNA repair
B2K_RS14790	COG1300	Membrane
B2K_RS14795	COG0735	belongs to the Fur family
B2K_RS14800	COG0686	Belongs to the AlaDH PNT family
B2K_RS14810	COG4974	Belongs to the 'phage' integrase family
B2K_RS14840	COG1686	Belongs to the peptidase S11 family
B2K_RS14845	COG1366	Belongs to the anti-sigma-factor antagonist family
B2K_RS14850	COG2172	sigma factor antagonist activity
B2K_RS14860	COG2155	Conserved Protein
B2K_RS14875	COG0697	spore germination
B2K_RS14880	COG0019	diaminopimelate decarboxylase activity
B2K_RS14885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B2K_RS14890	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B2K_RS14890	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B2K_RS14900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B2K_RS14900	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B2K_RS14905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B2K_RS14910	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B2K_RS14915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B2K_RS14925	COG3874	Sporulation protein YtfJ
B2K_RS14935	COG2135	peptidase activity
B2K_RS14940	COG1686	Belongs to the peptidase S11 family
B2K_RS14945	COG2715	membrane protein required for spore maturation
B2K_RS14950	COG0700	Nucleoside recognition
B2K_RS14960	COG1187	pseudouridine synthase activity
B2K_RS14965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2K_RS14970	COG1333	cytochrome c biogenesis protein
B2K_RS14975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B2K_RS14980	COG0745	RESPONSE REGULATOR receiver
B2K_RS14985	COG5002	protein histidine kinase activity
B2K_RS14990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B2K_RS14995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B2K_RS15005	COG1266	CAAX protease self-immunity
B2K_RS15015	COG0726	polysaccharide deacetylase
B2K_RS15025	COG4862	establishment of competence for transformation
B2K_RS15030	COG0358	DNA primase activity
B2K_RS15035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B2K_RS15040	COG2339	peptidase activity
B2K_RS15045	COG2959	enzyme of heme biosynthesis
B2K_RS15065	COG0204	Acyl-transferase
B2K_RS15070	COG0539	negative regulation of cytoplasmic translation
B2K_RS15075	COG1304	FMN binding
B2K_RS15095	COG1160	GTP binding
B2K_RS15100	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B2K_RS15120	COG0633	Ferredoxin
B2K_RS15140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B2K_RS15145	COG0776	regulation of translation
B2K_RS15180	COG0163	prenyltransferase activity
B2K_RS15185	COG0142	geranyltranstransferase activity
B2K_RS15190	COG0105	UTP biosynthetic process
B2K_RS15195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B2K_RS15200	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B2K_RS15205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B2K_RS15220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B2K_RS15225	COG0134	indole-3-glycerol-phosphate synthase activity
B2K_RS15230	COG0135	phosphoribosylanthranilate isomerase activity
B2K_RS15235	COG0133	tryptophan synthase activity
B2K_RS15240	COG0159	tryptophan synthase activity
B2K_RS15245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B2K_RS15250	COG0287	Prephenate dehydrogenase
B2K_RS15275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B2K_RS15280	COG5582	Belongs to the UPF0302 family
B2K_RS15290	COG0723	plastoquinol--plastocyanin reductase activity
B2K_RS15315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2K_RS15320	COG1694	Mazg nucleotide pyrophosphohydrolase
B2K_RS15330	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B2K_RS15335	COG1803	Methylglyoxal synthase
B2K_RS15340	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B2K_RS15345	COG0438	transferase activity, transferring glycosyl groups
B2K_RS15365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B2K_RS15370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B2K_RS15375	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B2K_RS15385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B2K_RS15385	COG1199	ATP-dependent helicase activity
B2K_RS15390	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B2K_RS15395	COG0306	phosphate transporter
B2K_RS15400	COG1392	Phosphate transport regulator
B2K_RS15405	COG0402	S-adenosylhomocysteine deaminase activity
B2K_RS15420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B2K_RS15425	COG0860	N-Acetylmuramoyl-L-alanine amidase
B2K_RS15440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B2K_RS15450	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B2K_RS15455	COG1132	(ABC) transporter
B2K_RS15460	COG1132	(ABC) transporter
B2K_RS15465	COG0739	heme binding
B2K_RS15465	COG0741	lytic transglycosylase activity
B2K_RS15465	COG1196	nuclear chromosome segregation
B2K_RS15475	COG1131	(ABC) transporter
B2K_RS15490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B2K_RS15495	COG1846	Transcriptional regulator
B2K_RS15500	COG0564	pseudouridine synthase activity
B2K_RS15505	COG0116	Belongs to the methyltransferase superfamily
B2K_RS15505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B2K_RS15515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B2K_RS15520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B2K_RS15525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B2K_RS15530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B2K_RS15535	COG0297	glycogen (starch) synthase activity
B2K_RS15540	COG5002	protein histidine kinase activity
B2K_RS15550	COG0428	transporter
B2K_RS15555	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B2K_RS15555	COG0392	lysyltransferase activity
B2K_RS15560	COG4251	negative regulation of phosphorylation
B2K_RS15560	COG3706	GGDEF domain
B2K_RS15560	COG2203	Gaf domain
B2K_RS15560	COG5001	Diguanylate cyclase
B2K_RS15590	COG1547	Domain of unknown function (DUF309)
B2K_RS15600	COG5002	protein histidine kinase activity
B2K_RS15600	COG3850	Histidine kinase
B2K_RS15605	COG0288	reversible hydration of carbon dioxide
B2K_RS15610	COG4918	Iron-sulphur cluster biosynthesis
B2K_RS15615	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B2K_RS15625	COG0697	spore germination
B2K_RS15640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B2K_RS15645	COG1116	anion transmembrane transporter activity
B2K_RS15650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS15680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B2K_RS15690	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B2K_RS15700	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B2K_RS15705	COG1923	regulation of RNA biosynthetic process
B2K_RS15710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2K_RS15715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B2K_RS15735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B2K_RS15740	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS15750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B2K_RS15755	COG0464	growth
B2K_RS15760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B2K_RS15765	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
B2K_RS15770	COG0789	Transcriptional regulator
B2K_RS15775	COG0174	glutamine synthetase
B2K_RS15780	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B2K_RS15785	COG0791	NLP P60 protein
B2K_RS15785	COG1388	LysM domain
B2K_RS15790	COG4224	UPF0291 protein
B2K_RS15795	COG0667	Aldo Keto reductase
B2K_RS15805	COG1011	Hydrolase
B2K_RS15810	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B2K_RS15815	COG0646	methionine synthase
B2K_RS15815	COG1410	methionine synthase
B2K_RS15820	COG1234	tRNA 3'-trailer cleavage
B2K_RS15835	COG1346	cytolysis
B2K_RS15850	COG1988	membrane-bound metal-dependent
B2K_RS15865	COG1216	Glycosyl transferase, family 2
B2K_RS15880	COG1562	ergosterol biosynthetic process
B2K_RS15895	COG1205	dead DEAH box helicase
B2K_RS15895	COG1111	helicase
B2K_RS15900	COG3359	exonuclease
B2K_RS15905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B2K_RS15910	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B2K_RS15920	COG1119	ATPase activity
B2K_RS15925	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
B2K_RS15930	COG2226	methyltransferase
B2K_RS15955	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B2K_RS15960	COG2856	Zn peptidase
B2K_RS15980	COG2002	toxin-antitoxin pair type II binding
B2K_RS15995	COG5377	YqaJ viral recombinase family
B2K_RS16000	COG3723	Recombinational DNA repair protein, rece pathway
B2K_RS16020	COG0305	Participates in initiation and elongation during chromosome replication
B2K_RS16065	COG4626	Terminase
B2K_RS16065	COG1802	Transcriptional regulator
B2K_RS16160	COG5632	N-Acetylmuramoyl-L-alanine amidase
B2K_RS16160	COG3409	Peptidoglycan-binding domain 1 protein
B2K_RS16225	COG1131	(ABC) transporter
B2K_RS16230	COG1725	Transcriptional regulator
B2K_RS16335	COG1363	Peptidase, m42
B2K_RS16340	COG0488	(ABC) transporter
B2K_RS16345	COG0488	(ABC) transporter
B2K_RS16365	COG5002	protein histidine kinase activity
B2K_RS16370	COG2197	response regulator
B2K_RS16380	COG2860	membrane
B2K_RS16395	COG3293	Transposase
B2K_RS16420	COG1733	regulation of RNA biosynthetic process
B2K_RS16440	COG4682	membrane
B2K_RS16455	COG2382	esterase
B2K_RS16455	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS16460	COG0515	serine threonine protein kinase
B2K_RS16465	COG1090	epimerase
B2K_RS16480	COG2207	Transcriptional regulator
B2K_RS16480	COG1609	Transcriptional regulator
B2K_RS16490	COG0667	Aldo Keto reductase
B2K_RS16520	COG1733	regulation of RNA biosynthetic process
B2K_RS16530	COG2226	methyltransferase
B2K_RS16535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B2K_RS16535	COG3153	acetyltransferase
B2K_RS16540	COG0456	acetyltransferase
B2K_RS16550	COG2032	superoxide dismutase activity
B2K_RS16555	COG0583	DNA-binding transcription factor activity
B2K_RS16560	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B2K_RS16575	COG0714	Associated with various cellular activities
B2K_RS16580	COG0386	Belongs to the glutathione peroxidase family
B2K_RS16590	COG1606	tRNA processing
B2K_RS16595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B2K_RS16600	COG1136	(ABC) transporter
B2K_RS16630	COG5002	protein histidine kinase activity
B2K_RS16640	COG3973	AAA domain
B2K_RS16735	COG0739	heme binding
B2K_RS16740	COG2814	Major facilitator Superfamily
B2K_RS16760	COG1272	protein, Hemolysin III
B2K_RS16770	COG0840	transmembrane signaling receptor activity
B2K_RS16770	COG3290	protein histidine kinase activity
B2K_RS16775	COG0523	cobalamin synthesis protein
B2K_RS16780	COG0735	belongs to the Fur family
B2K_RS16785	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B2K_RS16790	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B2K_RS16795	COG4208	sulfate ABC transporter
B2K_RS16800	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B2K_RS16805	COG1073	alpha beta
B2K_RS16810	COG5583	Uncharacterized small protein (DUF2292)
B2K_RS16815	COG0431	NADPH-dependent FMN reductase
B2K_RS16820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B2K_RS16825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS16830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS16835	COG1116	anion transmembrane transporter activity
B2K_RS16840	COG0196	riboflavin kinase activity
B2K_RS16845	COG1116	anion transmembrane transporter activity
B2K_RS16850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS16860	COG0667	Aldo Keto reductase
B2K_RS16865	COG2814	Major facilitator Superfamily
B2K_RS16870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2K_RS16875	COG0765	amino acid transport
B2K_RS16880	COG1126	abc transporter atp-binding protein
B2K_RS16900	COG0492	ferredoxin-NADP+ reductase activity
B2K_RS16915	COG2268	Band 7 protein
B2K_RS16925	COG0534	Mate efflux family protein
B2K_RS16930	COG0572	uridine kinase
B2K_RS16935	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS16945	COG0366	Alpha amylase catalytic
B2K_RS16950	COG1979	alcohol dehydrogenase
B2K_RS16955	COG2814	Major facilitator Superfamily
B2K_RS17030	COG2186	Transcriptional regulator
B2K_RS17040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B2K_RS17045	COG3958	Transketolase
B2K_RS17050	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS17075	COG1120	ATPase activity
B2K_RS17080	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS17085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS17095	COG2364	Membrane
B2K_RS17100	COG2153	protein acetylation
B2K_RS17105	COG1846	Transcriptional regulator
B2K_RS17120	COG0640	Transcriptional regulator
B2K_RS17130	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
B2K_RS17150	COG1309	transcriptional regulator
B2K_RS17155	COG1064	alcohol dehydrogenase
B2K_RS17185	COG2207	Transcriptional regulator
B2K_RS17185	COG1609	Transcriptional regulator
B2K_RS17190	COG3250	beta-galactosidase activity
B2K_RS17205	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS17240	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
B2K_RS17250	COG0778	Nitroreductase
B2K_RS17255	COG1846	Transcriptional regulator
B2K_RS17265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B2K_RS17270	COG1073	alpha beta
B2K_RS17300	COG1053	succinate dehydrogenase
B2K_RS17305	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B2K_RS17315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS17345	COG2890	protein-(glutamine-N5) methyltransferase activity
B2K_RS17350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B2K_RS17375	COG4912	Dna alkylation repair
B2K_RS17390	COG5002	protein histidine kinase activity
B2K_RS17400	COG1733	regulation of RNA biosynthetic process
B2K_RS17405	COG2226	methyltransferase
B2K_RS17430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2K_RS17465	COG2508	Transcriptional regulator
B2K_RS17470	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B2K_RS17480	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B2K_RS17485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B2K_RS17490	COG2080	2 iron, 2 sulfur cluster binding
B2K_RS17500	COG2201	protein-glutamate methylesterase activity
B2K_RS17520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS17530	COG0655	NAD(P)H dehydrogenase (quinone) activity
B2K_RS17535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B2K_RS17540	COG0402	S-adenosylhomocysteine deaminase activity
B2K_RS17545	COG3195	allantoin biosynthetic process
B2K_RS17545	COG3648	Uricase
B2K_RS17555	COG2351	hydroxyisourate hydrolase activity
B2K_RS17560	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B2K_RS17565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2K_RS17570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B2K_RS17575	COG0405	Gamma-glutamyltransferase
B2K_RS17580	COG2059	Chromate
B2K_RS17590	COG0674	pyruvate-flavodoxin oxidoreductase activity
B2K_RS17625	COG4221	oxidoreductase activity
B2K_RS17645	COG1956	GAF domain-containing protein
B2K_RS17650	COG1307	EDD domain protein, DegV family
B2K_RS17690	COG2949	membrane
B2K_RS17700	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS17715	COG0477	Major facilitator Superfamily
B2K_RS17730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B2K_RS17740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B2K_RS17745	COG0686	Belongs to the AlaDH PNT family
B2K_RS17750	COG2508	Transcriptional regulator
B2K_RS17750	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B2K_RS17755	COG1113	amino acid transport
B2K_RS17760	COG2226	methyltransferase
B2K_RS17775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B2K_RS17790	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B2K_RS17795	COG2733	membrane
B2K_RS17825	COG3250	beta-galactosidase activity
B2K_RS17855	COG1476	TRANSCRIPTIONal
B2K_RS17885	COG0662	Cupin 2, conserved barrel domain protein
B2K_RS17885	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
B2K_RS17910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B2K_RS17980	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS17985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2K_RS17995	COG0596	Alpha beta hydrolase
B2K_RS18015	COG3481	metal-dependent phosphohydrolase, HD sub domain
B2K_RS18030	COG2723	6-phospho-beta-galactosidase activity
B2K_RS18035	COG0217	transcriptional regulatory protein
B2K_RS18065	COG1309	transcriptional regulator
B2K_RS18080	COG1752	Esterase of the alpha-beta hydrolase superfamily
B2K_RS18095	COG1175	transmembrane transport
B2K_RS18100	COG0395	ABC-type sugar transport system, permease component
B2K_RS18120	COG0653	protein targeting
B2K_RS18160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B2K_RS18185	COG0024	Methionine aminopeptidase
B2K_RS18200	COG3631	Ketosteroid isomerase-related protein
B2K_RS18205	COG1309	transcriptional regulator
B2K_RS18215	COG1695	Transcriptional regulator
B2K_RS18235	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B2K_RS18240	COG0454	-acetyltransferase
B2K_RS18295	COG0154	amidase activity
B2K_RS18305	COG0667	Aldo Keto reductase
B2K_RS18310	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B2K_RS18310	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B2K_RS18320	COG4974	Belongs to the 'phage' integrase family
B2K_RS18340	COG0372	Belongs to the citrate synthase family
B2K_RS18350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B2K_RS18360	COG1653	transport
B2K_RS18365	COG1175	transmembrane transport
B2K_RS18370	COG0395	ABC-type sugar transport system, permease component
B2K_RS18380	COG1653	transport
B2K_RS18385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2K_RS18395	COG0559	Belongs to the binding-protein-dependent transport system permease family
B2K_RS18415	COG0697	spore germination
B2K_RS18435	COG2322	membrane
B2K_RS18480	COG0582	viral genome integration into host DNA
B2K_RS18495	COG4753	response regulator
B2K_RS18495	COG2207	Transcriptional regulator
B2K_RS18500	COG2972	Histidine kinase
B2K_RS18510	COG0395	ABC-type sugar transport system, permease component
B2K_RS18515	COG4209	transmembrane transport
B2K_RS18525	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B2K_RS18545	COG2378	regulation of single-species biofilm formation
B2K_RS18585	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS18590	COG1733	regulation of RNA biosynthetic process
B2K_RS18605	COG3250	beta-galactosidase activity
B2K_RS18620	COG3250	beta-galactosidase activity
B2K_RS18640	COG3507	Belongs to the glycosyl hydrolase 43 family
B2K_RS18650	COG1472	Belongs to the glycosyl hydrolase 3 family
B2K_RS18660	COG0395	ABC-type sugar transport system, permease component
B2K_RS18665	COG4209	transmembrane transport
B2K_RS18675	COG2207	Transcriptional regulator
B2K_RS18675	COG4753	response regulator
B2K_RS18680	COG2972	Histidine kinase
B2K_RS18700	COG0395	ABC-type sugar transport system, permease component
B2K_RS18705	COG1175	transmembrane transport
B2K_RS18730	COG1175	transmembrane transport
B2K_RS18735	COG1653	transport
B2K_RS18755	COG2249	NAD(P)H dehydrogenase (quinone) activity
B2K_RS18760	COG1733	regulation of RNA biosynthetic process
B2K_RS18765	COG2814	Major facilitator Superfamily
B2K_RS18890	COG0395	ABC-type sugar transport system, permease component
B2K_RS18895	COG4209	transmembrane transport
B2K_RS18900	COG2205	protein histidine kinase activity
B2K_RS18900	COG0745	RESPONSE REGULATOR receiver
B2K_RS18900	COG3292	Two component regulator propeller
B2K_RS18935	COG0024	Methionine aminopeptidase
B2K_RS18940	COG2318	DinB family
B2K_RS18950	COG0529	Catalyzes the synthesis of activated sulfate
B2K_RS18960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B2K_RS18985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B2K_RS18995	COG0189	ligase activity
B2K_RS19005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2K_RS19030	COG4282	regulation of fungal-type cell wall biogenesis
B2K_RS19055	COG2378	regulation of single-species biofilm formation
B2K_RS19065	COG0583	DNA-binding transcription factor activity
B2K_RS19075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B2K_RS19085	COG1960	acyl-CoA dehydrogenase activity
B2K_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS19105	COG4753	response regulator
B2K_RS19105	COG2207	Transcriptional regulator
B2K_RS19110	COG2972	Histidine kinase
B2K_RS19115	COG0395	ABC-type sugar transport system, permease component
B2K_RS19120	COG4209	transmembrane transport
B2K_RS19125	COG1653	transport
B2K_RS19135	COG0395	ABC-type sugar transport system, permease component
B2K_RS19140	COG4209	transmembrane transport
B2K_RS19150	COG4753	response regulator
B2K_RS19150	COG2207	Transcriptional regulator
B2K_RS19155	COG2972	Histidine kinase
B2K_RS19160	COG2207	Transcriptional regulator
B2K_RS19160	COG4753	response regulator
B2K_RS19165	COG2207	Transcriptional regulator
B2K_RS19165	COG4753	response regulator
B2K_RS19170	COG2972	Histidine kinase
B2K_RS19180	COG3507	Belongs to the glycosyl hydrolase 43 family
B2K_RS19190	COG1902	pentaerythritol trinitrate reductase activity
B2K_RS19190	COG0446	pyridine nucleotide-disulphide oxidoreductase
B2K_RS19200	COG1178	ABC-type Fe3 transport system permease component
B2K_RS19210	COG1840	ABC-type Fe3 transport system, periplasmic component
B2K_RS19220	COG1609	Transcriptional regulator
B2K_RS19225	COG1733	regulation of RNA biosynthetic process
B2K_RS19230	COG2249	NAD(P)H dehydrogenase (quinone) activity
B2K_RS19235	COG1653	transport
B2K_RS19240	COG2207	Transcriptional regulator
B2K_RS19240	COG4753	response regulator
B2K_RS19245	COG2972	Histidine kinase
B2K_RS19250	COG1653	transport
B2K_RS19255	COG3250	beta-galactosidase activity
B2K_RS19265	COG0395	ABC-type sugar transport system, permease component
B2K_RS19270	COG1175	transmembrane transport
B2K_RS19275	COG1653	transport
B2K_RS19295	COG1408	metallophosphoesterase
B2K_RS19305	COG2207	Transcriptional regulator
B2K_RS19325	COG0395	ABC-type sugar transport system, permease component
B2K_RS19330	COG1175	transmembrane transport
B2K_RS19335	COG1653	transport
B2K_RS19345	COG1361	Conserved repeat domain
B2K_RS19345	COG2911	Protein conserved in bacteria
B2K_RS19345	COG3266	domain, Protein
B2K_RS19355	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS19375	COG3340	Belongs to the peptidase S51 family
B2K_RS19390	COG2207	Transcriptional regulator
B2K_RS19395	COG1846	Transcriptional regulator
B2K_RS19400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B2K_RS19425	COG0346	lactoylglutathione lyase activity
B2K_RS19430	COG0640	Transcriptional regulator
B2K_RS19445	COG0574	Belongs to the PEP-utilizing enzyme family
B2K_RS19445	COG3848	Pyruvate phosphate dikinase
B2K_RS19460	COG0477	Major facilitator Superfamily
B2K_RS19465	COG1733	regulation of RNA biosynthetic process
B2K_RS19475	COG3833	ABC-type maltose transport systems, permease component
B2K_RS19480	COG1175	transmembrane transport
B2K_RS19490	COG2204	response regulator
B2K_RS19495	COG2972	Histidine kinase
B2K_RS19495	COG0745	RESPONSE REGULATOR receiver
B2K_RS19505	COG4221	oxidoreductase activity
B2K_RS19525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B2K_RS19530	COG0583	DNA-binding transcription factor activity
B2K_RS19540	COG0667	Aldo Keto reductase
B2K_RS19565	COG2017	converts alpha-aldose to the beta-anomer
B2K_RS19570	COG3507	Belongs to the glycosyl hydrolase 43 family
B2K_RS19575	COG1653	transport
B2K_RS19580	COG0395	ABC-type sugar transport system, permease component
B2K_RS19585	COG4209	transmembrane transport
B2K_RS19590	COG2207	Transcriptional regulator
B2K_RS19600	COG0673	inositol 2-dehydrogenase activity
B2K_RS19645	COG3209	COG3209 Rhs family protein
B2K_RS19660	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS19675	COG0657	acetylesterase activity
B2K_RS19695	COG2746	aminoglycoside 3-N-acetyltransferase activity
B2K_RS19700	COG2182	Extracellular solute-binding protein
B2K_RS19705	COG1175	transmembrane transport
B2K_RS19710	COG3833	ABC-type maltose transport systems, permease component
B2K_RS19725	COG2267	carboxylic ester hydrolase activity
B2K_RS19730	COG0488	(ABC) transporter
B2K_RS19745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B2K_RS19750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B2K_RS19755	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS19760	COG1233	COG1233 Phytoene dehydrogenase and related
B2K_RS19805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B2K_RS19815	COG2197	response regulator
B2K_RS19820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B2K_RS19840	COG1045	serine acetyltransferase
B2K_RS19855	COG0569	domain protein
B2K_RS19865	COG2801	Transposase and inactivated derivatives
B2K_RS19900	COG1653	transport
B2K_RS19905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS19910	COG0778	Nitroreductase
B2K_RS19915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS19920	COG0667	Aldo Keto reductase
B2K_RS19930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS19940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS19945	COG1132	(ABC) transporter
B2K_RS19950	COG1132	(ABC) transporter
B2K_RS19955	COG0395	ABC-type sugar transport system, permease component
B2K_RS19960	COG1175	transmembrane transport
B2K_RS19975	COG0395	ABC-type sugar transport system, permease component
B2K_RS19990	COG3842	ATPase activity
B2K_RS19995	COG0247	lactate metabolic process
B2K_RS20000	COG0277	FAD linked oxidase domain protein
B2K_RS20005	COG3655	Transcriptional regulator
B2K_RS20025	COG2311	Membrane
B2K_RS20060	COG0583	DNA-binding transcription factor activity
B2K_RS20065	COG0477	Major facilitator Superfamily
B2K_RS20075	COG1846	Transcriptional regulator
B2K_RS20090	COG1522	sequence-specific DNA binding
B2K_RS20100	COG1064	alcohol dehydrogenase
B2K_RS20105	COG3961	Belongs to the TPP enzyme family
B2K_RS20110	COG0586	Pfam SNARE associated Golgi protein
B2K_RS20115	COG1653	transport
B2K_RS20120	COG2972	Histidine kinase
B2K_RS20125	COG1653	transport
B2K_RS20130	COG0395	ABC-type sugar transport system, permease component
B2K_RS20135	COG4209	transmembrane transport
B2K_RS20140	COG4753	response regulator
B2K_RS20140	COG2207	Transcriptional regulator
B2K_RS20145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS20150	COG0778	Nitroreductase
B2K_RS20155	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS20170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B2K_RS20175	COG0861	Integral membrane protein TerC family
B2K_RS20185	COG1309	transcriptional regulator
B2K_RS20210	COG0840	transmembrane signaling receptor activity
B2K_RS20215	COG5001	Diguanylate cyclase
B2K_RS20215	COG2203	Gaf domain
B2K_RS20215	COG4251	negative regulation of phosphorylation
B2K_RS20215	COG3706	GGDEF domain
B2K_RS20225	COG3708	Transcriptional regulator
B2K_RS20225	COG2207	Transcriptional regulator
B2K_RS20250	COG2329	Antibiotic biosynthesis monooxygenase
B2K_RS20255	COG1695	Transcriptional regulator
B2K_RS20265	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B2K_RS20305	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B2K_RS20310	COG3639	organic phosphonate transmembrane transporter activity
B2K_RS20320	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B2K_RS20330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B2K_RS20335	COG2962	Rard protein
B2K_RS20350	COG2207	Transcriptional regulator
B2K_RS20355	COG1653	transport
B2K_RS20360	COG0395	ABC-type sugar transport system, permease component
B2K_RS20365	COG4209	transmembrane transport
B2K_RS20375	COG2755	lipolytic protein G-D-S-L family
B2K_RS20380	COG3708	Transcriptional regulator
B2K_RS20380	COG2207	Transcriptional regulator
B2K_RS20385	COG1063	alcohol dehydrogenase
B2K_RS20395	COG1609	Transcriptional regulator
B2K_RS20400	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS20410	COG1309	transcriptional regulator
B2K_RS20430	COG0778	Nitroreductase
B2K_RS20440	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS20445	COG4447	cellulose binding
B2K_RS20445	COG4733	cellulase activity
B2K_RS20450	COG4124	Belongs to the glycosyl hydrolase 26 family
B2K_RS20455	COG3507	Belongs to the glycosyl hydrolase 43 family
B2K_RS20470	COG2223	nitrite transmembrane transporter activity
B2K_RS20485	COG2819	hydrolase of the alpha beta superfamily
B2K_RS20490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS20495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS20500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B2K_RS20505	COG2207	Transcriptional regulator
B2K_RS20505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B2K_RS20520	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS20525	COG2207	Transcriptional regulator
B2K_RS20530	COG3866	Pectate lyase
B2K_RS20535	COG3940	Belongs to the glycosyl hydrolase 43 family
B2K_RS20540	COG1902	pentaerythritol trinitrate reductase activity
B2K_RS20545	COG1132	(ABC) transporter
B2K_RS20550	COG2814	Major facilitator Superfamily
B2K_RS20555	COG0583	DNA-binding transcription factor activity
B2K_RS20570	COG0596	Alpha beta hydrolase
B2K_RS20575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS20580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B2K_RS20585	COG2175	clavaminate synthase activity
B2K_RS20595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS20605	COG0395	ABC-type sugar transport system, permease component
B2K_RS20610	COG4209	transmembrane transport
B2K_RS20615	COG4753	response regulator
B2K_RS20615	COG2207	Transcriptional regulator
B2K_RS20620	COG2972	Histidine kinase
B2K_RS20635	COG2207	Transcriptional regulator
B2K_RS20640	COG4124	Belongs to the glycosyl hydrolase 26 family
B2K_RS20645	COG0477	Major facilitator Superfamily
B2K_RS20650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS20655	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B2K_RS20665	COG2271	Major facilitator Superfamily
B2K_RS20670	COG0277	FAD linked oxidase domain protein
B2K_RS20690	COG0492	ferredoxin-NADP+ reductase activity
B2K_RS20695	COG1959	2 iron, 2 sulfur cluster binding
B2K_RS20700	COG2770	Histidine kinase
B2K_RS20700	COG2205	protein histidine kinase activity
B2K_RS20705	COG0745	RESPONSE REGULATOR receiver
B2K_RS20715	COG0516	GMP reductase activity
B2K_RS20715	COG0517	IMP dehydrogenase activity
B2K_RS20720	COG0745	RESPONSE REGULATOR receiver
B2K_RS20735	COG1131	(ABC) transporter
B2K_RS20750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2K_RS20755	COG0673	inositol 2-dehydrogenase activity
B2K_RS20785	COG0673	inositol 2-dehydrogenase activity
B2K_RS20795	COG1136	(ABC) transporter
B2K_RS20800	COG0577	efflux transmembrane transporter activity
B2K_RS20810	COG1136	(ABC) transporter
B2K_RS20810	COG0577	efflux transmembrane transporter activity
B2K_RS20830	COG1653	transport
B2K_RS20840	COG1653	transport
B2K_RS20855	COG0395	ABC-type sugar transport system, permease component
B2K_RS20860	COG1175	transmembrane transport
B2K_RS20925	COG3833	ABC-type maltose transport systems, permease component
B2K_RS20930	COG4209	transmembrane transport
B2K_RS20940	COG3842	ATPase activity
B2K_RS20945	COG1073	alpha beta
B2K_RS20950	COG4977	sequence-specific DNA binding
B2K_RS20950	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS20985	COG3250	beta-galactosidase activity
B2K_RS20995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2K_RS21000	COG1454	alcohol dehydrogenase
B2K_RS21010	COG3408	Glycogen debranching enzyme
B2K_RS21015	COG0395	ABC-type sugar transport system, permease component
B2K_RS21020	COG4209	transmembrane transport
B2K_RS21025	COG2972	Histidine kinase
B2K_RS21035	COG1653	transport
B2K_RS21055	COG3250	beta-galactosidase activity
B2K_RS21065	COG1850	ribulose-bisphosphate carboxylase activity
B2K_RS21075	COG0800	Aldolase
B2K_RS21080	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS21100	COG2207	Transcriptional regulator
B2K_RS21105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B2K_RS21110	COG3958	Transketolase
B2K_RS21115	COG3959	Transketolase, thiamine diphosphate binding domain
B2K_RS21125	COG1609	Transcriptional regulator
B2K_RS21135	COG1501	Belongs to the glycosyl hydrolase 31 family
B2K_RS21165	COG0697	spore germination
B2K_RS21170	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
B2K_RS21180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2K_RS21200	COG1193	negative regulation of DNA recombination
B2K_RS21235	COG0745	RESPONSE REGULATOR receiver
B2K_RS21240	COG5002	protein histidine kinase activity
B2K_RS21275	COG0583	DNA-binding transcription factor activity
B2K_RS21280	COG1910	domain protein
B2K_RS21285	COG0725	ABC transporter, periplasmic molybdate-binding protein
B2K_RS21290	COG4149	molybdate abc transporter
B2K_RS21315	COG2207	Transcriptional regulator
B2K_RS21325	COG1653	transport
B2K_RS21330	COG0395	ABC-type sugar transport system, permease component
B2K_RS21335	COG4209	transmembrane transport
B2K_RS21345	COG2124	cytochrome p450
B2K_RS21355	COG0688	phosphatidylethanolamine metabolic process
B2K_RS21360	COG2957	Belongs to the agmatine deiminase family
B2K_RS21370	COG0745	RESPONSE REGULATOR receiver
B2K_RS21375	COG2205	protein histidine kinase activity
B2K_RS21400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B2K_RS21405	COG0583	DNA-binding transcription factor activity
B2K_RS21445	COG0667	Aldo Keto reductase
B2K_RS21450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS21455	COG2249	NAD(P)H dehydrogenase (quinone) activity
B2K_RS21480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B2K_RS21485	COG0395	ABC-type sugar transport system, permease component
B2K_RS21490	COG1175	transmembrane transport
B2K_RS21500	COG2972	Histidine kinase
B2K_RS21505	COG2207	Transcriptional regulator
B2K_RS21505	COG4753	response regulator
B2K_RS21510	COG0789	Transcriptional regulator
B2K_RS21515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2K_RS21520	COG1733	regulation of RNA biosynthetic process
B2K_RS21540	COG1175	transmembrane transport
B2K_RS21545	COG3833	ABC-type maltose transport systems, permease component
B2K_RS21550	COG2972	Histidine kinase
B2K_RS21555	COG2207	Transcriptional regulator
B2K_RS21555	COG2207	Transcriptional regulator
B2K_RS21555	COG4753	response regulator
B2K_RS21555	COG4753	response regulator
B2K_RS21565	COG0789	Transcriptional regulator
B2K_RS21570	COG0697	spore germination
B2K_RS21580	COG0395	ABC-type sugar transport system, permease component
B2K_RS21585	COG4209	transmembrane transport
B2K_RS21595	COG2207	Transcriptional regulator
B2K_RS21595	COG4753	response regulator
B2K_RS21600	COG2972	Histidine kinase
B2K_RS21605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B2K_RS21615	COG2124	cytochrome p450
B2K_RS21625	COG2814	Major facilitator Superfamily
B2K_RS21630	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS21640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS21655	COG1929	Belongs to the glycerate kinase type-1 family
B2K_RS21680	COG3708	Transcriptional regulator
B2K_RS21680	COG2207	Transcriptional regulator
B2K_RS21685	COG2211	Major facilitator Superfamily
B2K_RS21690	COG4753	response regulator
B2K_RS21690	COG4753	response regulator
B2K_RS21690	COG2207	Transcriptional regulator
B2K_RS21690	COG2207	Transcriptional regulator
B2K_RS21695	COG3275	phosphorelay sensor kinase activity
B2K_RS21710	COG2197	response regulator
B2K_RS21715	COG2972	Histidine kinase
B2K_RS21720	COG1653	transport
B2K_RS21725	COG0395	ABC-type sugar transport system, permease component
B2K_RS21730	COG4209	transmembrane transport
B2K_RS21750	COG5297	Belongs to the glycosyl hydrolase family 6
B2K_RS21755	COG0583	DNA-binding transcription factor activity
B2K_RS21760	COG0697	spore germination
B2K_RS21775	COG1357	PFAM Pentapeptide repeats (8 copies)
B2K_RS21785	COG1733	regulation of RNA biosynthetic process
B2K_RS21795	COG1733	regulation of RNA biosynthetic process
B2K_RS21800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B2K_RS21805	COG4533	DNA binding
B2K_RS21810	COG2211	Major facilitator Superfamily
B2K_RS21820	COG0655	NAD(P)H dehydrogenase (quinone) activity
B2K_RS21825	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B2K_RS21835	COG3958	Transketolase
B2K_RS21840	COG3959	Transketolase, thiamine diphosphate binding domain
B2K_RS21845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2K_RS21850	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B2K_RS21875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B2K_RS21880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2K_RS21885	COG0601	transmembrane transport
B2K_RS21890	COG4608	Belongs to the ABC transporter superfamily
B2K_RS21895	COG0444	Belongs to the ABC transporter superfamily
B2K_RS21900	COG1473	amidohydrolase
B2K_RS21905	COG0747	negative chemotaxis
B2K_RS21915	COG0395	ABC-type sugar transport system, permease component
B2K_RS21920	COG1175	transmembrane transport
B2K_RS21935	COG0165	Argininosuccinate lyase
B2K_RS21950	COG2368	4-hydroxyphenylacetate
B2K_RS21960	COG0395	ABC-type sugar transport system, permease component
B2K_RS21965	COG1175	transmembrane transport
B2K_RS21975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS22010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS22015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS22030	COG1473	amidohydrolase
B2K_RS22035	COG0456	acetyltransferase
B2K_RS22040	COG1126	abc transporter atp-binding protein
B2K_RS22045	COG0765	amino acid transport
B2K_RS22050	COG0765	amino acid transport
B2K_RS22055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2K_RS22070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2K_RS22085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS22090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS22095	COG0583	DNA-binding transcription factor activity
B2K_RS22110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B2K_RS22120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS22125	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B2K_RS22140	COG3119	arylsulfatase activity
B2K_RS22145	COG0395	ABC-type sugar transport system, permease component
B2K_RS22150	COG4209	transmembrane transport
B2K_RS22155	COG1653	transport
B2K_RS22170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS22200	COG0346	lactoylglutathione lyase activity
B2K_RS22205	COG3739	integral membrane protein
B2K_RS22230	COG0640	Transcriptional regulator
B2K_RS22235	COG2205	protein histidine kinase activity
B2K_RS22240	COG0745	RESPONSE REGULATOR receiver
B2K_RS22270	COG0395	ABC-type sugar transport system, permease component
B2K_RS22280	COG2182	Extracellular solute-binding protein
B2K_RS22285	COG2207	Transcriptional regulator
B2K_RS22290	COG2972	Histidine kinase
B2K_RS22295	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS22320	COG2207	Transcriptional regulator
B2K_RS22320	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS22335	COG0697	spore germination
B2K_RS22355	COG1760	l-serine dehydratase
B2K_RS22360	COG1760	l-serine dehydratase
B2K_RS22370	COG0667	Aldo Keto reductase
B2K_RS22375	COG0697	spore germination
B2K_RS22410	COG2884	Cell division ATP-binding protein ftsE
B2K_RS22425	COG1045	serine acetyltransferase
B2K_RS22500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B2K_RS22515	COG1131	(ABC) transporter
B2K_RS22550	COG3507	Belongs to the glycosyl hydrolase 43 family
B2K_RS22560	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B2K_RS22600	COG1672	PFAM Archaeal ATPase
B2K_RS22600	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B2K_RS22605	COG0534	Mate efflux family protein
B2K_RS22610	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B2K_RS22615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B2K_RS22625	COG0542	response to heat
B2K_RS22630	COG1653	transport
B2K_RS22635	COG0840	transmembrane signaling receptor activity
B2K_RS22645	COG0534	Mate efflux family protein
B2K_RS22670	COG0697	spore germination
B2K_RS22725	COG1132	(ABC) transporter
B2K_RS22730	COG1132	(ABC) transporter
B2K_RS22740	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B2K_RS22750	COG0714	Associated with various cellular activities
B2K_RS22770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B2K_RS22770	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B2K_RS22785	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
B2K_RS22790	COG0535	radical SAM domain protein
B2K_RS22800	COG2151	metal-sulfur cluster biosynthetic enzyme
B2K_RS22815	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B2K_RS22840	COG0477	Major facilitator Superfamily
B2K_RS22845	COG3173	Aminoglycoside phosphotransferase
B2K_RS22850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B2K_RS22875	COG4154	Belongs to the RbsD FucU family
B2K_RS22890	COG1607	acyl-coa hydrolase
B2K_RS22895	COG0583	DNA-binding transcription factor activity
B2K_RS22905	COG2321	neutral zinc metallopeptidase
B2K_RS22920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS22955	COG0300	oxidoreductase activity
B2K_RS22955	COG3321	synthase
B2K_RS22955	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS22955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B2K_RS22955	COG0318	PFAM AMP-dependent synthetase and ligase
B2K_RS22960	COG2207	Transcriptional regulator
B2K_RS22995	COG0628	permease
B2K_RS23005	COG0534	Mate efflux family protein
B2K_RS23015	COG0596	Alpha beta hydrolase
B2K_RS23020	COG3961	Belongs to the TPP enzyme family
B2K_RS23030	COG2135	peptidase activity
B2K_RS23055	COG0210	DNA helicase
B2K_RS23060	COG0531	amino acid
B2K_RS23065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS23105	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B2K_RS23120	COG3290	protein histidine kinase activity
B2K_RS23120	COG3829	transcription factor binding
B2K_RS23175	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B2K_RS23205	COG2972	Histidine kinase
B2K_RS23215	COG0395	ABC-type sugar transport system, permease component
B2K_RS23220	COG1175	transmembrane transport
B2K_RS23230	COG1309	transcriptional regulator
B2K_RS23235	COG2814	Major facilitator Superfamily
B2K_RS23240	COG3142	Participates in the control of copper homeostasis
B2K_RS23245	COG2732	(Barnase) inhibitor
B2K_RS23255	COG0531	amino acid
B2K_RS23270	COG0697	spore germination
B2K_RS23280	COG0039	L-malate dehydrogenase activity
B2K_RS23285	COG2116	formate transmembrane transporter activity
B2K_RS23305	COG3424	synthase
B2K_RS23320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2K_RS23320	COG0723	plastoquinol--plastocyanin reductase activity
B2K_RS23325	COG1309	transcriptional regulator
B2K_RS23330	COG0702	epimerase
B2K_RS23335	COG3631	Ketosteroid isomerase-related protein
B2K_RS23360	COG1361	Conserved repeat domain
B2K_RS23365	COG4257	antibiotic catabolic process
B2K_RS23370	COG0739	heme binding
B2K_RS23370	COG0741	lytic transglycosylase activity
B2K_RS23370	COG1196	nuclear chromosome segregation
B2K_RS23380	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B2K_RS23395	COG0697	spore germination
B2K_RS23400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B2K_RS23425	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B2K_RS23430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B2K_RS23435	COG2169	Transcriptional regulator
B2K_RS23440	COG2363	Small membrane protein
B2K_RS23445	COG1764	response to oxidative stress
B2K_RS23460	COG0477	Major facilitator Superfamily
B2K_RS23475	COG0326	Molecular chaperone. Has ATPase activity
B2K_RS23485	COG1562	ergosterol biosynthetic process
B2K_RS23495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B2K_RS23500	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS23510	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B2K_RS23525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B2K_RS23535	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B2K_RS23540	COG2390	Transcriptional regulator
B2K_RS23555	COG0095	Lipoate-protein ligase
B2K_RS23570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS23575	COG0778	Nitroreductase
B2K_RS23580	COG1959	2 iron, 2 sulfur cluster binding
B2K_RS23590	COG3507	Belongs to the glycosyl hydrolase 43 family
B2K_RS23595	COG3534	alpha-L-arabinofuranosidase
B2K_RS23600	COG0395	ABC-type sugar transport system, permease component
B2K_RS23605	COG1175	transmembrane transport
B2K_RS23630	COG2755	lipolytic protein G-D-S-L family
B2K_RS23630	COG3401	FG-GAP repeat protein
B2K_RS23635	COG1475	DNA binding
B2K_RS23640	COG0366	Alpha amylase catalytic
B2K_RS23645	COG2208	phosphoserine phosphatase activity
B2K_RS23650	COG0596	Alpha beta hydrolase
B2K_RS23665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B2K_RS23710	COG3118	belongs to the thioredoxin family
B2K_RS23715	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B2K_RS23720	COG3401	FG-GAP repeat protein
B2K_RS23725	COG1253	flavin adenine dinucleotide binding
B2K_RS23735	COG1653	transport
B2K_RS23740	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B2K_RS23750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2K_RS23755	COG0477	Major facilitator Superfamily
B2K_RS23765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2K_RS23780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B2K_RS23785	COG0006	proline dipeptidase activity
B2K_RS23805	COG0697	spore germination
B2K_RS23825	COG3153	acetyltransferase
B2K_RS23875	COG1131	(ABC) transporter
B2K_RS23885	COG0456	acetyltransferase
B2K_RS23915	COG2208	phosphoserine phosphatase activity
B2K_RS23940	COG1278	Cold shock
B2K_RS23945	COG0705	Rhomboid family
B2K_RS23970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B2K_RS23975	COG1309	transcriptional regulator
B2K_RS23995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B2K_RS24000	COG4608	Belongs to the ABC transporter superfamily
B2K_RS24015	COG0601	transmembrane transport
B2K_RS24020	COG0747	negative chemotaxis
B2K_RS24040	COG1063	alcohol dehydrogenase
B2K_RS24050	COG5577	PFAM Coat F domain
B2K_RS24080	COG2719	SpoVR family
B2K_RS24085	COG2718	Belongs to the UPF0229 family
B2K_RS24090	COG2766	serine protein kinase
B2K_RS24110	COG5002	protein histidine kinase activity
B2K_RS24110	COG2198	Histidine kinase
B2K_RS24110	COG0784	Response regulator, receiver
B2K_RS24120	COG0346	lactoylglutathione lyase activity
B2K_RS24130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B2K_RS24140	COG0626	cystathionine gamma-synthase activity
B2K_RS24145	COG1428	Deoxynucleoside kinase
B2K_RS24155	COG5001	Diguanylate cyclase
B2K_RS24155	COG3300	MHYT domain
B2K_RS24165	COG4166	transmembrane transport
B2K_RS24170	COG1115	amino acid carrier protein
B2K_RS24220	COG2124	cytochrome p450
B2K_RS24235	COG0659	secondary active sulfate transmembrane transporter activity
B2K_RS24240	COG0288	reversible hydration of carbon dioxide
B2K_RS24265	COG4474	Belongs to the UPF0398 family
B2K_RS24290	COG0531	amino acid
B2K_RS24300	COG0137	argininosuccinate synthase activity
B2K_RS24320	COG0596	Alpha beta hydrolase
B2K_RS24340	COG0534	Mate efflux family protein
B2K_RS24355	COG1199	ATP-dependent helicase activity
B2K_RS24370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2K_RS24375	COG0601	transmembrane transport
B2K_RS24385	COG4608	Belongs to the ABC transporter superfamily
B2K_RS24390	COG0444	Belongs to the ABC transporter superfamily
B2K_RS24395	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
B2K_RS24430	COG4191	Histidine kinase
B2K_RS24435	COG3842	ATPase activity
B2K_RS24455	COG0667	Aldo Keto reductase
B2K_RS24460	COG2318	DinB family
B2K_RS24470	COG0640	Transcriptional regulator
B2K_RS24490	COG2234	aminopeptidase activity
B2K_RS24495	COG1472	Belongs to the glycosyl hydrolase 3 family
B2K_RS24530	COG1309	transcriptional regulator
B2K_RS24535	COG2814	Major facilitator Superfamily
B2K_RS24550	COG1683	Conserved Protein
B2K_RS24555	COG0488	(ABC) transporter
B2K_RS24565	COG1959	2 iron, 2 sulfur cluster binding
B2K_RS24575	COG1653	transport
B2K_RS24580	COG0395	ABC-type sugar transport system, permease component
B2K_RS24585	COG4209	transmembrane transport
B2K_RS24595	COG2972	Histidine kinase
B2K_RS24630	COG2124	cytochrome p450
B2K_RS24650	COG0395	ABC-type sugar transport system, permease component
B2K_RS24655	COG4209	transmembrane transport
B2K_RS24665	COG2207	Transcriptional regulator
B2K_RS24695	COG0697	spore germination
B2K_RS24730	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B2K_RS24735	COG0667	Aldo Keto reductase
B2K_RS24755	COG4999	Histidine kinase
B2K_RS24755	COG3850	Histidine kinase
B2K_RS24755	COG3437	response regulator, receiver
B2K_RS24755	COG2205	protein histidine kinase activity
B2K_RS24790	COG0531	amino acid
B2K_RS24805	COG0697	spore germination
B2K_RS24820	COG1063	alcohol dehydrogenase
B2K_RS24835	COG0791	NLP P60 protein
B2K_RS24845	COG1619	proteins homologs of microcin C7 resistance protein MccF
B2K_RS24850	COG4166	transmembrane transport
B2K_RS24855	COG0444	Belongs to the ABC transporter superfamily
B2K_RS24860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2K_RS24865	COG0601	transmembrane transport
B2K_RS24870	COG2362	D-Aminopeptidase
B2K_RS24880	COG4377	Putative membrane peptidase family (DUF2324)
B2K_RS24885	COG3344	reverse transcriptase
B2K_RS24890	COG3401	FG-GAP repeat protein
B2K_RS24900	COG1653	transport
B2K_RS24905	COG0395	ABC-type sugar transport system, permease component
B2K_RS24910	COG4209	transmembrane transport
B2K_RS24915	COG2207	Transcriptional regulator
B2K_RS24930	COG2755	lipolytic protein G-D-S-L family
B2K_RS24935	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B2K_RS24940	COG0395	ABC-type sugar transport system, permease component
B2K_RS24945	COG1175	transmembrane transport
B2K_RS24960	COG1653	transport
B2K_RS24965	COG4753	response regulator
B2K_RS24965	COG2207	Transcriptional regulator
B2K_RS24970	COG2972	Histidine kinase
B2K_RS24975	COG0561	phosphatase activity
B2K_RS24980	COG1051	belongs to the nudix hydrolase family
B2K_RS24990	COG2032	superoxide dismutase activity
B2K_RS25010	COG1295	ribonuclease BN
B2K_RS25015	COG2323	membrane
B2K_RS25020	COG2205	protein histidine kinase activity
B2K_RS25035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B2K_RS25050	COG4129	membrane
B2K_RS25055	COG0805	protein transport
B2K_RS25060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B2K_RS25080	COG1136	(ABC) transporter
B2K_RS25085	COG1785	Belongs to the alkaline phosphatase family
B2K_RS25090	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B2K_RS25095	COG1335	isochorismatase
B2K_RS25100	COG3973	AAA domain
B2K_RS25105	COG0456	acetyltransferase
B2K_RS25110	COG1247	-acetyltransferase
B2K_RS25150	COG3507	Belongs to the glycosyl hydrolase 43 family
B2K_RS25150	COG2382	esterase
B2K_RS25150	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS25165	COG4753	response regulator
B2K_RS25165	COG2207	Transcriptional regulator
B2K_RS25170	COG2972	Histidine kinase
B2K_RS25180	COG0395	ABC-type sugar transport system, permease component
B2K_RS25185	COG4209	transmembrane transport
B2K_RS25195	COG2205	protein histidine kinase activity
B2K_RS25205	COG0697	spore germination
B2K_RS25215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B2K_RS25220	COG2222	sugar isomerase
B2K_RS25225	COG0252	asparaginase activity
B2K_RS25230	COG1082	Xylose isomerase domain protein TIM barrel
B2K_RS25235	COG0395	ABC-type sugar transport system, permease component
B2K_RS25240	COG1175	transmembrane transport
B2K_RS25245	COG1653	transport
B2K_RS25250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2K_RS25255	COG2188	Transcriptional regulator
B2K_RS25260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2K_RS25270	COG1643	Atp-dependent helicase
B2K_RS25290	COG4895	conserved protein (DUF2196)
B2K_RS25310	COG2217	Heavy metal translocating P-type atpase
B2K_RS25315	COG0864	Transcriptional regulator
B2K_RS25320	COG4550	Control of competence regulator ComK, YlbF/YmcA
B2K_RS25325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B2K_RS25330	COG4869	propanediol catabolic process
B2K_RS25335	COG1013	pyruvate-flavodoxin oxidoreductase activity
B2K_RS25340	COG0674	pyruvate-flavodoxin oxidoreductase activity
B2K_RS25340	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B2K_RS25350	COG2359	stage V sporulation protein S
B2K_RS25355	COG1692	metallophosphoesterase
B2K_RS25360	COG1418	mRNA catabolic process
B2K_RS25365	COG2137	regulation of response to DNA damage stimulus
B2K_RS25370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B2K_RS25375	COG1058	Belongs to the CinA family
B2K_RS25375	COG1546	Belongs to the CinA family
B2K_RS25380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B2K_RS25385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B2K_RS25400	COG1426	Protein conserved in bacteria
B2K_RS25420	COG0300	oxidoreductase activity
B2K_RS25425	COG0612	Peptidase, M16
B2K_RS25430	COG0612	Peptidase, M16
B2K_RS25440	COG1674	ftsk spoiiie
B2K_RS25450	COG0740	serine-type endopeptidase activity
B2K_RS25455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B2K_RS25465	COG0527	aspartate kinase activity
B2K_RS25470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B2K_RS25475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B2K_RS25480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B2K_RS25485	COG0756	dUTP diphosphatase activity
B2K_RS25490	COG0612	Peptidase, M16
B2K_RS25495	COG0726	polysaccharide deacetylase
B2K_RS25500	COG1185	polyribonucleotide nucleotidyltransferase activity
B2K_RS25505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B2K_RS25510	COG0196	riboflavin kinase activity
B2K_RS25515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B2K_RS25520	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B2K_RS25525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B2K_RS25530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B2K_RS25535	COG1358	cellular component organization or biogenesis
B2K_RS25545	COG0195	Participates in both transcription termination and antitermination
B2K_RS25550	COG0779	Required for maturation of 30S ribosomal subunits
B2K_RS25555	COG2176	DNA-directed DNA polymerase activity
B2K_RS25560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B2K_RS25565	COG0750	zinc metalloprotease
B2K_RS25570	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B2K_RS25575	COG4589	Belongs to the CDS family
B2K_RS25580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B2K_RS25585	COG0233	cytoplasmic translational termination
B2K_RS25590	COG0528	UMP kinase activity
B2K_RS25595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B2K_RS25600	COG0052	Belongs to the universal ribosomal protein uS2 family
B2K_RS25625	COG1191	sigma factor activity
B2K_RS25635	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B2K_RS25640	COG1776	CheC inhibitor of MCP methylation
B2K_RS25645	COG0835	chemotaxis
B2K_RS25650	COG0643	Histidine kinase
B2K_RS25650	COG2198	Histidine kinase
B2K_RS25655	COG2201	protein-glutamate methylesterase activity
B2K_RS25660	COG0455	bacterial-type flagellum organization
B2K_RS25665	COG1419	protein localization to endoplasmic reticulum
B2K_RS25670	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B2K_RS25675	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B2K_RS25680	COG1684	flagellar biosynthetic protein fliR
B2K_RS25685	COG1987	bacterial-type flagellum assembly
B2K_RS25690	COG1338	Plays a role in the flagellum-specific transport system
B2K_RS25695	COG3190	flagellar
B2K_RS25700	COG2201	protein-glutamate methylesterase activity
B2K_RS25705	COG1776	CheC inhibitor of MCP methylation
B2K_RS25705	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B2K_RS25710	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B2K_RS25720	COG1582	Flagellar protein (FlbD)
B2K_RS25725	COG4786	Flagellar basal body rod
B2K_RS25735	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B2K_RS25740	COG3144	bacterial-type flagellum assembly
B2K_RS25750	COG2882	bacterial-type flagellum organization
B2K_RS25755	COG1157	protein secretion by the type III secretion system
B2K_RS25765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B2K_RS25770	COG1766	The M ring may be actively involved in energy transduction
B2K_RS25775	COG1677	Flagellar hook-basal body complex protein FliE
B2K_RS25780	COG1558	bacterial-type flagellum-dependent cell motility
B2K_RS25785	COG1815	bacterial-type flagellum-dependent cell motility
B2K_RS25790	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B2K_RS25795	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B2K_RS25800	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B2K_RS25805	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B2K_RS25810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B2K_RS25815	COG0758	DNA mediated transformation
B2K_RS25820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B2K_RS25825	COG0045	succinate-CoA ligase (ADP-forming) activity
B2K_RS25835	COG0606	chelatase, subunit chli
B2K_RS25845	COG2257	FlhB HrpN YscU SpaS Family
B2K_RS25860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B2K_RS25875	COG0681	Belongs to the peptidase S26 family
B2K_RS25880	COG0335	large ribosomal subunit rRNA binding
B2K_RS25895	COG1361	Conserved repeat domain
B2K_RS25905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B2K_RS25915	COG0228	four-way junction DNA binding
B2K_RS25920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B2K_RS25925	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B2K_RS25930	COG0552	protein localization to endoplasmic reticulum
B2K_RS25935	COG1196	nuclear chromosome segregation
B2K_RS25945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B2K_RS25950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B2K_RS25955	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS25960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B2K_RS25965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B2K_RS25970	COG0416	fatty acid biosynthetic process
B2K_RS25975	COG1349	DNA-binding transcription factor activity
B2K_RS25975	COG2050	protein possibly involved in aromatic compounds catabolism
B2K_RS25985	COG1323	Belongs to the UPF0348 family
B2K_RS25995	COG3480	Lon protease (S16) C-terminal proteolytic domain
B2K_RS26005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B2K_RS26010	COG0742	ribosomal rna small subunit methyltransferase
B2K_RS26020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2K_RS26030	COG2755	lipolytic protein G-D-S-L family
B2K_RS26040	COG0346	lactoylglutathione lyase activity
B2K_RS26065	COG1904	glucuronate isomerase
B2K_RS26080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B2K_RS26090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B2K_RS26095	COG1309	transcriptional regulator
B2K_RS26105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B2K_RS26110	COG1307	EDD domain protein, DegV family
B2K_RS26115	COG1461	Dihydroxyacetone kinase
B2K_RS26120	COG1302	Protein conserved in bacteria
B2K_RS26125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B2K_RS26140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B2K_RS26145	COG1162	GTPase activity
B2K_RS26150	COG0515	serine threonine protein kinase
B2K_RS26150	COG2815	serine threonine protein kinase
B2K_RS26155	COG0631	protein serine/threonine phosphatase activity
B2K_RS26160	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B2K_RS26165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B2K_RS26165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B2K_RS26180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B2K_RS26185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B2K_RS26190	COG1758	RNA polymerase activity
B2K_RS26195	COG0194	GDP metabolic process
B2K_RS26200	COG2052	Domain of unknown function (DUF370)
B2K_RS26205	COG1561	YicC-like family, N-terminal region
B2K_RS26210	COG0646	methionine synthase
B2K_RS26210	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B2K_RS26220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B2K_RS26225	COG1293	RNA-binding protein homologous to eukaryotic snRNP
B2K_RS26255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B2K_RS26260	COG0613	PHP domain protein
B2K_RS26265	COG0583	DNA-binding transcription factor activity
B2K_RS26275	COG4471	UPF0298 protein
B2K_RS26295	COG1061	Type III restriction enzyme res subunit
B2K_RS26305	COG0018	arginyl-trna synthetase
B2K_RS26315	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B2K_RS26320	COG1473	amidohydrolase
B2K_RS26330	COG0772	Belongs to the SEDS family
B2K_RS26340	COG0387	Pfam Sodium calcium exchanger
B2K_RS26345	COG4838	Belongs to the UPF0358 family
B2K_RS26355	COG2309	aminopeptidase activity
B2K_RS26365	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B2K_RS26375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2K_RS26380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B2K_RS26385	COG0454	-acetyltransferase
B2K_RS26390	COG0123	including yeast histone deacetylase and acetoin utilization protein
B2K_RS26395	COG0423	glycine-tRNA ligase activity
B2K_RS26400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B2K_RS26405	COG1609	Transcriptional regulator
B2K_RS26425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B2K_RS26430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2K_RS26430	COG1263	PTS System
B2K_RS26430	COG2190	(PTS) system
B2K_RS26440	COG0352	thiamine-phosphate diphosphorylase activity
B2K_RS26445	COG1832	CoA-binding protein
B2K_RS26455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B2K_RS26460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B2K_RS26465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B2K_RS26470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B2K_RS26475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B2K_RS26485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B2K_RS26490	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS26495	COG1070	Carbohydrate kinase
B2K_RS26505	COG1609	Transcriptional regulator
B2K_RS26530	COG4493	Belongs to the UPF0637 family
B2K_RS26560	COG0395	ABC-type sugar transport system, permease component
B2K_RS26565	COG4209	transmembrane transport
B2K_RS26570	COG1653	transport
B2K_RS26580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B2K_RS26590	COG1982	Orn Lys Arg decarboxylase major
B2K_RS26600	COG0561	phosphatase activity
B2K_RS26610	COG3906	Belongs to the UPF0473 family
B2K_RS26620	COG0321	lipoyl(octanoyl) transferase activity
B2K_RS26620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B2K_RS26635	COG0840	transmembrane signaling receptor activity
B2K_RS26640	COG3852	Histidine kinase
B2K_RS26645	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B2K_RS26655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2K_RS26690	COG1793	dna ligase
B2K_RS26695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B2K_RS26715	COG0346	lactoylglutathione lyase activity
B2K_RS26775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B2K_RS26780	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B2K_RS26795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B2K_RS26815	COG1136	(ABC) transporter
B2K_RS26815	COG0577	efflux transmembrane transporter activity
B2K_RS26825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B2K_RS26830	COG1136	(ABC) transporter
B2K_RS26830	COG0577	efflux transmembrane transporter activity
B2K_RS26835	COG0840	transmembrane signaling receptor activity
B2K_RS26840	COG3935	DnaD domain protein
B2K_RS26845	COG0017	Asparaginyl-tRNA synthetase
B2K_RS26850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B2K_RS26855	COG1250	3-hydroxyacyl-CoA dehydrogenase
B2K_RS26860	COG0066	3-isopropylmalate dehydratase activity
B2K_RS26865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B2K_RS26870	COG0583	DNA-binding transcription factor activity
B2K_RS26875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B2K_RS26880	COG0436	Aminotransferase
B2K_RS26890	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B2K_RS26905	COG1850	ribulose-bisphosphate carboxylase activity
B2K_RS26910	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
B2K_RS26915	COG0235	Class ii aldolase
B2K_RS26925	COG1131	(ABC) transporter
B2K_RS26935	COG1595	DNA-templated transcription, initiation
B2K_RS26940	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B2K_RS26950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B2K_RS26960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B2K_RS26965	COG0540	Belongs to the ATCase OTCase family
B2K_RS26970	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B2K_RS26980	COG1473	amidohydrolase
B2K_RS26985	COG0436	Aminotransferase
B2K_RS26990	COG0564	pseudouridine synthase activity
B2K_RS26995	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B2K_RS27010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B2K_RS27015	COG3599	regulation of cell shape
B2K_RS27020	COG2302	S4 RNA-binding domain
B2K_RS27030	COG1799	cell septum assembly
B2K_RS27035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B2K_RS27045	COG1873	PFAM PRC-barrel domain
B2K_RS27050	COG1191	sigma factor activity
B2K_RS27055	COG1191	sigma factor activity
B2K_RS27065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B2K_RS27070	COG0849	cell division
B2K_RS27075	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B2K_RS27080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B2K_RS27090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B2K_RS27095	COG0772	Belongs to the SEDS family
B2K_RS27100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B2K_RS27105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B2K_RS27110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B2K_RS27120	COG0768	penicillin binding
B2K_RS27125	COG0768	penicillin binding
B2K_RS27135	COG0275	rRNA processing
B2K_RS27140	COG2001	Belongs to the MraZ family
B2K_RS27150	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B2K_RS27155	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
B2K_RS27165	COG4608	Belongs to the ABC transporter superfamily
B2K_RS27170	COG0444	Belongs to the ABC transporter superfamily
B2K_RS27175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2K_RS27180	COG0601	transmembrane transport
B2K_RS27185	COG4166	transmembrane transport
B2K_RS27230	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B2K_RS27255	COG1217	gtp-binding protein TYPA
B2K_RS27260	COG0861	Integral membrane protein TerC family
B2K_RS27265	COG0301	tRNA thio-modification
B2K_RS27270	COG1104	cysteine desulfurase activity
B2K_RS27275	COG0741	lytic transglycosylase activity
B2K_RS27280	COG4709	membrane
B2K_RS27300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B2K_RS27305	COG2384	SAM-dependent methyltransferase
B2K_RS27320	COG0358	DNA primase activity
B2K_RS27325	COG1671	Belongs to the UPF0178 family
B2K_RS27330	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B2K_RS27335	COG1381	Involved in DNA repair and RecF pathway recombination
B2K_RS27340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B2K_RS27350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B2K_RS27355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B2K_RS27360	COG1480	7TM receptor with intracellular HD hydrolase
B2K_RS27365	COG1702	phosphate starvation-inducible protein PhoH
B2K_RS27385	COG4864	UPF0365 protein
B2K_RS27395	COG1610	YqeY-like protein
B2K_RS27400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B2K_RS27405	COG0537	adenosine 5'-monophosphoramidase activity
B2K_RS27425	COG0420	3'-5' exonuclease activity
B2K_RS27430	COG1074	ATP-dependent DNA helicase activity
B2K_RS27435	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B2K_RS27460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B2K_RS27465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B2K_RS27470	COG1994	Peptidase M50
B2K_RS27500	COG0459	protein refolding
B2K_RS27505	COG1420	regulation of RNA biosynthetic process
B2K_RS27515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B2K_RS27520	COG0481	GTPase activity
B2K_RS27540	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B2K_RS27545	COG0268	Binds directly to 16S ribosomal RNA
B2K_RS27550	COG1466	dna polymerase III delta subunit
B2K_RS27560	COG1595	DNA-templated transcription, initiation
B2K_RS27575	COG2116	formate transmembrane transporter activity
B2K_RS27580	COG2146	nitrite reductase [NAD(P)H] activity
B2K_RS27585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B2K_RS27590	COG0658	competence protein
B2K_RS27590	COG2333	competence protein COMEC
B2K_RS27605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B2K_RS27610	COG0495	leucyl-tRNA aminoacylation
B2K_RS27615	COG2226	methyltransferase
B2K_RS27620	COG2996	Protein conserved in bacteria
B2K_RS27625	COG0799	negative regulation of ribosome biogenesis
B2K_RS27630	COG1713	HD superfamily hydrolase involved in NAD metabolism
B2K_RS27635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B2K_RS27640	COG1534	Rna-binding protein
B2K_RS27645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B2K_RS27650	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B2K_RS27655	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B2K_RS27660	COG3546	catalase activity
B2K_RS27675	COG1305	Transglutaminase-like
B2K_RS27685	COG0714	Associated with various cellular activities
B2K_RS27695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B2K_RS27705	COG2323	membrane
B2K_RS27725	COG0204	Acyl-transferase
B2K_RS27725	COG0318	PFAM AMP-dependent synthetase and ligase
B2K_RS27730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2K_RS27735	COG2201	protein-glutamate methylesterase activity
B2K_RS27755	COG4106	trans-aconitate 2-methyltransferase activity
B2K_RS27805	COG3458	cephalosporin-C deacetylase activity
B2K_RS27810	COG0840	transmembrane signaling receptor activity
B2K_RS27815	COG1132	(ABC) transporter
B2K_RS27820	COG1132	(ABC) transporter
B2K_RS27825	COG1126	abc transporter atp-binding protein
B2K_RS27830	COG0765	amino acid transport
B2K_RS27835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2K_RS27870	COG0584	glycerophosphoryl diester phosphodiesterase
B2K_RS27875	COG0840	transmembrane signaling receptor activity
B2K_RS27880	COG1744	ABC transporter substrate-binding protein PnrA-like
B2K_RS27895	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B2K_RS27900	COG3437	response regulator, receiver
B2K_RS27900	COG2205	protein histidine kinase activity
B2K_RS27900	COG3850	Histidine kinase
B2K_RS27900	COG4999	Histidine kinase
B2K_RS27920	COG0583	DNA-binding transcription factor activity
B2K_RS27925	COG0840	transmembrane signaling receptor activity
B2K_RS27940	COG0318	PFAM AMP-dependent synthetase and ligase
B2K_RS27945	COG1960	acyl-CoA dehydrogenase activity
B2K_RS27950	COG0183	Belongs to the thiolase family
B2K_RS27955	COG1024	Enoyl-CoA hydratase
B2K_RS27955	COG1250	3-hydroxyacyl-CoA dehydrogenase
B2K_RS27960	COG2181	nitrate reductase activity
B2K_RS27960	COG0247	lactate metabolic process
B2K_RS27965	COG1309	transcriptional regulator
B2K_RS27970	COG2086	electron transfer activity
B2K_RS27975	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B2K_RS28000	COG0673	inositol 2-dehydrogenase activity
B2K_RS28005	COG0412	Dienelactone hydrolase
B2K_RS28010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B2K_RS28035	COG3290	protein histidine kinase activity
B2K_RS28050	COG1280	lysine exporter protein (LysE YggA)
B2K_RS28055	COG1113	amino acid transport
B2K_RS28060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS28075	COG3940	Belongs to the glycosyl hydrolase 43 family
B2K_RS28080	COG0395	ABC-type sugar transport system, permease component
B2K_RS28085	COG1175	transmembrane transport
B2K_RS28090	COG1653	transport
B2K_RS28095	COG3940	Belongs to the glycosyl hydrolase 43 family
B2K_RS28130	COG0673	inositol 2-dehydrogenase activity
B2K_RS28140	COG1012	belongs to the aldehyde dehydrogenase family
B2K_RS28145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2K_RS28150	COG1082	Xylose isomerase domain protein TIM barrel
B2K_RS28155	COG3962	Belongs to the TPP enzyme family
B2K_RS28160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B2K_RS28160	COG2207	Transcriptional regulator
B2K_RS28165	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B2K_RS28170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS28175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS28185	COG1653	transport
B2K_RS28195	COG0395	ABC-type sugar transport system, permease component
B2K_RS28200	COG4209	transmembrane transport
B2K_RS28205	COG2207	Transcriptional regulator
B2K_RS28230	COG0463	Glycosyl transferase, family 2
B2K_RS28250	COG1215	transferase activity, transferring glycosyl groups
B2K_RS28255	COG0438	transferase activity, transferring glycosyl groups
B2K_RS28265	COG0438	transferase activity, transferring glycosyl groups
B2K_RS28275	COG3401	FG-GAP repeat protein
B2K_RS28280	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS28280	COG2382	esterase
B2K_RS28300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS28310	COG2207	Transcriptional regulator
B2K_RS28335	COG1609	Transcriptional regulator
B2K_RS28345	COG5297	Belongs to the glycosyl hydrolase family 6
B2K_RS28385	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B2K_RS28385	COG0456	acetyltransferase
B2K_RS28390	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B2K_RS28395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2K_RS28400	COG1122	ATPase activity
B2K_RS28405	COG1122	ATPase activity
B2K_RS28410	COG1268	BioY protein
B2K_RS28430	COG2186	Transcriptional regulator
B2K_RS28435	COG1556	Lactate utilization protein
B2K_RS28440	COG1139	Iron-sulfur cluster binding protein
B2K_RS28445	COG0247	lactate metabolic process
B2K_RS28455	COG1349	DNA-binding transcription factor activity
B2K_RS28460	COG1070	Carbohydrate kinase
B2K_RS28465	COG4952	isomerase
B2K_RS28475	COG3347	Dehydrogenase
B2K_RS28475	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS28495	COG2814	Major facilitator Superfamily
B2K_RS28505	COG5297	Belongs to the glycosyl hydrolase family 6
B2K_RS28505	COG4447	cellulose binding
B2K_RS28520	COG3534	alpha-L-arabinofuranosidase
B2K_RS28525	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B2K_RS28530	COG2755	lipolytic protein G-D-S-L family
B2K_RS28575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B2K_RS28580	COG1132	(ABC) transporter
B2K_RS28585	COG3706	GGDEF domain
B2K_RS28595	COG3940	Belongs to the glycosyl hydrolase 43 family
B2K_RS28605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2K_RS28610	COG0765	amino acid transport
B2K_RS28615	COG1126	abc transporter atp-binding protein
B2K_RS28625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B2K_RS28635	COG1940	carbohydrate kinase activity
B2K_RS28645	COG0791	NLP P60 protein
B2K_RS28645	COG1388	LysM domain
B2K_RS28645	COG3103	Sh3 type 3 domain protein
B2K_RS28650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2K_RS28655	COG1960	acyl-CoA dehydrogenase activity
B2K_RS28670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B2K_RS28680	COG1733	regulation of RNA biosynthetic process
B2K_RS28695	COG2217	Heavy metal translocating P-type atpase
B2K_RS28715	COG0583	DNA-binding transcription factor activity
B2K_RS28720	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B2K_RS28725	COG0833	amino acid
B2K_RS28730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B2K_RS28735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B2K_RS28740	COG3829	transcription factor binding
B2K_RS28745	COG2249	NAD(P)H dehydrogenase (quinone) activity
B2K_RS28750	COG1733	regulation of RNA biosynthetic process
B2K_RS28755	COG2207	Transcriptional regulator
B2K_RS28760	COG3275	phosphorelay sensor kinase activity
B2K_RS28770	COG0395	ABC-type sugar transport system, permease component
B2K_RS28775	COG4209	transmembrane transport
B2K_RS28800	COG4753	response regulator
B2K_RS28800	COG2207	Transcriptional regulator
B2K_RS28825	COG2318	DinB family
B2K_RS28830	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS28840	COG0583	DNA-binding transcription factor activity
B2K_RS28845	COG3275	phosphorelay sensor kinase activity
B2K_RS28850	COG2207	Transcriptional regulator
B2K_RS28850	COG4753	response regulator
B2K_RS28860	COG0395	ABC-type sugar transport system, permease component
B2K_RS28865	COG4209	transmembrane transport
B2K_RS28880	COG1609	Transcriptional regulator
B2K_RS28905	COG0395	ABC-type sugar transport system, permease component
B2K_RS28910	COG4209	transmembrane transport
B2K_RS28920	COG0300	oxidoreductase activity
B2K_RS28935	COG2972	Histidine kinase
B2K_RS28940	COG2207	Transcriptional regulator
B2K_RS28940	COG4753	response regulator
B2K_RS28945	COG1879	ABC-type sugar transport system periplasmic component
B2K_RS28950	COG1172	Belongs to the binding-protein-dependent transport system permease family
B2K_RS28960	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B2K_RS28965	COG2207	Transcriptional regulator
B2K_RS28970	COG4948	Mandelate Racemase Muconate Lactonizing
B2K_RS28975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2K_RS28980	COG1012	belongs to the aldehyde dehydrogenase family
B2K_RS28985	COG1653	transport
B2K_RS28990	COG0395	ABC-type sugar transport system, permease component
B2K_RS28995	COG4209	transmembrane transport
B2K_RS29000	COG4608	Belongs to the ABC transporter superfamily
B2K_RS29010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2K_RS29015	COG0601	transmembrane transport
B2K_RS29020	COG0747	negative chemotaxis
B2K_RS29040	COG1653	transport
B2K_RS29045	COG4753	response regulator
B2K_RS29045	COG2207	Transcriptional regulator
B2K_RS29065	COG1136	(ABC) transporter
B2K_RS29080	COG0395	ABC-type sugar transport system, permease component
B2K_RS29085	COG4209	transmembrane transport
B2K_RS29100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2K_RS29105	COG1522	sequence-specific DNA binding
B2K_RS29110	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B2K_RS29110	COG0456	acetyltransferase
B2K_RS29115	COG0737	Belongs to the 5'-nucleotidase family
B2K_RS29115	COG1525	nuclease
B2K_RS29115	COG4085	toxin activity
B2K_RS29130	COG2197	response regulator
B2K_RS29145	COG0318	PFAM AMP-dependent synthetase and ligase
B2K_RS29180	COG1309	transcriptional regulator
B2K_RS29190	COG3706	GGDEF domain
B2K_RS29205	COG0508	dehydrogenase complex catalyzes the overall conversion of
B2K_RS29225	COG0095	Lipoate-protein ligase
B2K_RS29250	COG0745	RESPONSE REGULATOR receiver
B2K_RS29280	COG5002	protein histidine kinase activity
B2K_RS29285	COG0768	penicillin binding
B2K_RS29290	COG0840	transmembrane signaling receptor activity
B2K_RS29295	COG0826	peptidase U32
B2K_RS29300	COG0826	peptidase U32
B2K_RS29305	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B2K_RS29320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B2K_RS29325	COG4472	Bacterial protein of unknown function (DUF965)
B2K_RS29345	COG0697	spore germination
B2K_RS29350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B2K_RS29360	COG0628	permease
B2K_RS29375	COG1104	cysteine desulfurase activity
B2K_RS29380	COG1959	2 iron, 2 sulfur cluster binding
B2K_RS29385	COG0482	sulfurtransferase activity
B2K_RS29390	COG1253	flavin adenine dinucleotide binding
B2K_RS29400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B2K_RS29405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B2K_RS29410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B2K_RS29415	COG0124	histidyl-tRNA synthetase
B2K_RS29430	COG1490	D-aminoacyl-tRNA deacylase activity
B2K_RS29435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B2K_RS29440	COG5337	Spore coat protein CotH
B2K_RS29460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B2K_RS29465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B2K_RS29465	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B2K_RS29470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B2K_RS29485	COG2244	polysaccharide biosynthetic process
B2K_RS29490	COG2323	membrane
B2K_RS29500	COG1862	Preprotein translocase
B2K_RS29515	COG2385	sporulation resulting in formation of a cellular spore
B2K_RS29520	COG2255	four-way junction helicase activity
B2K_RS29525	COG0632	four-way junction helicase activity
B2K_RS29530	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B2K_RS29550	COG0681	Belongs to the peptidase S26 family
B2K_RS29555	COG1388	LysM domain
B2K_RS29555	COG0860	N-Acetylmuramoyl-L-alanine amidase
B2K_RS29560	COG1285	pathogenesis
B2K_RS29565	COG0077	Prephenate dehydratase
B2K_RS29570	COG0083	homoserine kinase activity
B2K_RS29575	COG0460	homoserine dehydrogenase
B2K_RS29580	COG4492	Belongs to the UPF0735 family
B2K_RS29590	COG1119	ATPase activity
B2K_RS29595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B2K_RS29600	COG0243	molybdopterin cofactor binding
B2K_RS29605	COG2223	nitrite transmembrane transporter activity
B2K_RS29610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B2K_RS29620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B2K_RS29625	COG2868	ribosomal protein
B2K_RS29630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B2K_RS29640	COG1994	Peptidase M50
B2K_RS29650	COG0772	Belongs to the SEDS family
B2K_RS29655	COG2894	cell division
B2K_RS29660	COG0850	regulation of cytokinetic process
B2K_RS29675	COG1077	Cell shape determining protein MreB Mrl
B2K_RS29680	COG2003	Belongs to the UPF0758 family
B2K_RS29685	COG0424	maF-like protein
B2K_RS29705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B2K_RS29710	COG0285	dihydrofolate synthase activity
B2K_RS29715	COG0525	valine-tRNA ligase activity
B2K_RS29720	COG1388	LysM domain
B2K_RS29725	COG0564	pseudouridine synthase activity
B2K_RS29730	COG5434	Belongs to the glycosyl hydrolase 28 family
B2K_RS29730	COG4632	Exopolysaccharide biosynthesis protein
B2K_RS29735	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B2K_RS29740	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B2K_RS29745	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B2K_RS29750	COG0113	porphobilinogen synthase activity
B2K_RS29765	COG1648	precorrin-2 dehydrogenase activity
B2K_RS29765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B2K_RS29770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B2K_RS29785	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B2K_RS29795	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B2K_RS29805	COG0470	DNA polymerase III
B2K_RS29805	COG1067	ATP-dependent peptidase activity
B2K_RS29810	COG0860	N-Acetylmuramoyl-L-alanine amidase
B2K_RS29815	COG2861	carbohydrate metabolic process
B2K_RS29825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B2K_RS29830	COG0740	serine-type endopeptidase activity
B2K_RS29840	COG0544	peptidyl-prolyl cis-trans isomerase activity
B2K_RS29870	COG0367	asparagine synthase
B2K_RS29875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B2K_RS29880	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B2K_RS29885	COG5401	PFAM Sporulation and spore germination
B2K_RS29895	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B2K_RS29910	COG3453	Protein conserved in bacteria
B2K_RS29910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B2K_RS29920	COG1940	carbohydrate kinase activity
B2K_RS29935	COG4566	intracellular signal transduction
B2K_RS29950	COG2270	Major facilitator Superfamily
B2K_RS29965	COG0753	catalase activity
B2K_RS29975	COG2197	response regulator
B2K_RS29990	COG0475	glutathione-regulated potassium exporter activity
B2K_RS29995	COG3963	phosphatidate phosphatase activity
B2K_RS30000	COG1970	mechanosensitive ion channel activity
B2K_RS30005	COG2340	Cysteine-rich secretory protein family
B2K_RS30010	COG4549	nuclear export factor GLE1
B2K_RS30015	COG2197	response regulator
B2K_RS30020	COG4585	Histidine kinase
B2K_RS30025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B2K_RS30075	COG0463	Glycosyl transferase, family 2
B2K_RS30110	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
B2K_RS30115	COG1091	dTDP-4-dehydrorhamnose reductase activity
B2K_RS30125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B2K_RS30135	COG0438	transferase activity, transferring glycosyl groups
B2K_RS30140	COG0519	Catalyzes the synthesis of GMP from XMP
B2K_RS30165	COG1846	Transcriptional regulator
B2K_RS30175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B2K_RS30180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B2K_RS30190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B2K_RS30195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B2K_RS30205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B2K_RS30210	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B2K_RS30215	COG1122	ATPase activity
B2K_RS30230	COG0688	phosphatidylethanolamine metabolic process
B2K_RS30235	COG2223	nitrite transmembrane transporter activity
B2K_RS30240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B2K_RS30240	COG2199	diguanylate cyclase activity
B2K_RS30250	COG0456	acetyltransferase
B2K_RS30260	COG4977	sequence-specific DNA binding
B2K_RS30260	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS30265	COG2066	Belongs to the glutaminase family
B2K_RS30270	COG4214	carbohydrate transport
B2K_RS30280	COG4213	ABC transporter substrate-binding protein
B2K_RS30285	COG2207	Transcriptional regulator
B2K_RS30285	COG4753	response regulator
B2K_RS30290	COG2972	Histidine kinase
B2K_RS30305	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
B2K_RS30310	COG1349	DNA-binding transcription factor activity
B2K_RS30325	COG4221	oxidoreductase activity
B2K_RS30340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B2K_RS30355	COG1846	Transcriptional regulator
B2K_RS30360	COG2814	Major facilitator Superfamily
B2K_RS30395	COG1053	succinate dehydrogenase
B2K_RS30395	COG3976	FMN-binding domain protein
B2K_RS30400	COG0583	DNA-binding transcription factor activity
B2K_RS30415	COG2258	MOSC domain
B2K_RS30430	COG1506	peptidase
B2K_RS30440	COG1595	DNA-templated transcription, initiation
B2K_RS30450	COG0300	oxidoreductase activity
B2K_RS30455	COG1406	Chemotaxis phosphatase CheX
B2K_RS30460	COG2720	vancomycin resistance protein
B2K_RS30480	COG1131	(ABC) transporter
B2K_RS30500	COG3458	cephalosporin-C deacetylase activity
B2K_RS30520	COG0647	UMP catabolic process
B2K_RS30540	COG1201	RNA secondary structure unwinding
B2K_RS30545	COG0789	Transcriptional regulator
B2K_RS30550	COG0477	Major facilitator Superfamily
B2K_RS30560	COG2814	Major facilitator Superfamily
B2K_RS30565	COG0583	DNA-binding transcription factor activity
B2K_RS30570	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B2K_RS30575	COG2755	lipolytic protein G-D-S-L family
B2K_RS30585	COG1472	Belongs to the glycosyl hydrolase 3 family
B2K_RS30590	COG2207	Transcriptional regulator
B2K_RS30590	COG4753	response regulator
B2K_RS30595	COG2972	Histidine kinase
B2K_RS30600	COG0395	ABC-type sugar transport system, permease component
B2K_RS30605	COG1175	transmembrane transport
B2K_RS30615	COG2182	Extracellular solute-binding protein
B2K_RS30620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2K_RS30620	COG1263	PTS System
B2K_RS30625	COG1263	PTS System
B2K_RS30625	COG2190	(PTS) system
B2K_RS30625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2K_RS30630	COG3711	transcriptional antiterminator
B2K_RS30640	COG1695	Transcriptional regulator
B2K_RS30680	COG0840	transmembrane signaling receptor activity
B2K_RS30685	COG0745	RESPONSE REGULATOR receiver
B2K_RS30690	COG5002	protein histidine kinase activity
B2K_RS30695	COG0534	Mate efflux family protein
B2K_RS30705	COG0500	methyltransferase
B2K_RS30710	COG5002	protein histidine kinase activity
B2K_RS30720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B2K_RS30725	COG2766	serine protein kinase
B2K_RS30735	COG1966	Carbon starvation protein
B2K_RS30740	COG3279	Response regulator of the LytR AlgR family
B2K_RS30745	COG3275	phosphorelay sensor kinase activity
B2K_RS30760	COG0726	polysaccharide deacetylase
B2K_RS30765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B2K_RS30770	COG0477	Major facilitator Superfamily
B2K_RS30790	COG2972	Histidine kinase
B2K_RS30795	COG2197	response regulator
B2K_RS30820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B2K_RS30825	COG0745	RESPONSE REGULATOR receiver
B2K_RS30845	COG1396	sequence-specific DNA binding
B2K_RS30850	COG1396	sequence-specific DNA binding
B2K_RS30885	COG1696	Membrane protein involved in D-alanine export
B2K_RS30895	COG5039	Polysaccharide pyruvyl transferase
B2K_RS30910	COG0662	Cupin 2, conserved barrel domain protein
B2K_RS30910	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
B2K_RS30915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B2K_RS30920	COG0438	transferase activity, transferring glycosyl groups
B2K_RS30940	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B2K_RS30945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B2K_RS30950	COG3944	biosynthesis protein
B2K_RS30960	COG0110	maltose O-acetyltransferase activity
B2K_RS30965	COG0297	glycogen (starch) synthase activity
B2K_RS30980	COG0438	transferase activity, transferring glycosyl groups
B2K_RS30995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B2K_RS31000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B2K_RS31005	COG0489	protein tyrosine kinase activity
B2K_RS31015	COG4464	protein tyrosine phosphatase activity
B2K_RS31025	COG1396	sequence-specific DNA binding
B2K_RS31030	COG0174	glutamine synthetase
B2K_RS31035	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B2K_RS31045	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B2K_RS31050	COG5002	protein histidine kinase activity
B2K_RS31050	COG3850	Histidine kinase
B2K_RS31055	COG0745	RESPONSE REGULATOR receiver
B2K_RS31060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2K_RS31070	COG0004	ammonium transporteR
B2K_RS31080	COG3584	3D domain protein
B2K_RS31085	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B2K_RS31105	COG0438	transferase activity, transferring glycosyl groups
B2K_RS31110	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B2K_RS31115	COG2602	Beta-lactamase
B2K_RS31120	COG0626	cystathionine gamma-synthase activity
B2K_RS31125	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B2K_RS31130	COG0598	Magnesium transport protein CorA
B2K_RS31145	COG0129	dihydroxy-acid dehydratase activity
B2K_RS31165	COG1607	acyl-coa hydrolase
B2K_RS31170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B2K_RS31175	COG4977	sequence-specific DNA binding
B2K_RS31180	COG0673	inositol 2-dehydrogenase activity
B2K_RS31185	COG0673	inositol 2-dehydrogenase activity
B2K_RS31190	COG0436	Aminotransferase
B2K_RS31210	COG0564	pseudouridine synthase activity
B2K_RS31215	COG2096	Adenosyltransferase
B2K_RS31225	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B2K_RS31230	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B2K_RS31240	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B2K_RS31245	COG1120	ATPase activity
B2K_RS31250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS31255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B2K_RS31270	COG0436	Aminotransferase
B2K_RS31275	COG1522	sequence-specific DNA binding
B2K_RS31285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B2K_RS31290	COG0477	Major facilitator Superfamily
B2K_RS31300	COG3766	membrane
B2K_RS31305	COG1842	Phage shock protein A
B2K_RS31310	COG1193	negative regulation of DNA recombination
B2K_RS31330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS31355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B2K_RS31355	COG0072	phenylalanine-tRNA ligase activity
B2K_RS31360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B2K_RS31365	COG3647	Membrane
B2K_RS31375	COG1528	Iron-storage protein
B2K_RS31390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B2K_RS31395	COG5001	Diguanylate cyclase
B2K_RS31425	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
B2K_RS31450	COG2315	Protein conserved in bacteria
B2K_RS31470	COG0667	Aldo Keto reductase
B2K_RS31480	COG1276	copper resistance
B2K_RS31480	COG2372	response to copper ion
B2K_RS31485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B2K_RS31490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B2K_RS31500	COG0745	RESPONSE REGULATOR receiver
B2K_RS31520	COG0730	response to heat
B2K_RS31525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B2K_RS31530	COG5566	PFAM Mor transcription activator
B2K_RS31535	COG1984	allophanate hydrolase subunit 2
B2K_RS31540	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B2K_RS31555	COG0737	Belongs to the 5'-nucleotidase family
B2K_RS31570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B2K_RS31600	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B2K_RS31605	COG1131	(ABC) transporter
B2K_RS31610	COG1587	Uroporphyrinogen-III synthase
B2K_RS31615	COG3584	3D domain protein
B2K_RS31620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B2K_RS31630	COG3290	protein histidine kinase activity
B2K_RS31640	COG1301	dicarboxylic acid transport
B2K_RS31655	COG0833	amino acid
B2K_RS31720	COG1131	(ABC) transporter
B2K_RS31725	COG4473	ABC transporter
B2K_RS31735	COG3011	Protein conserved in bacteria
B2K_RS31745	COG0596	Alpha beta hydrolase
B2K_RS31745	COG2945	thiolester hydrolase activity
B2K_RS31760	COG1129	ABC transporter
B2K_RS31790	COG0765	amino acid transport
B2K_RS31795	COG0765	amino acid transport
B2K_RS31800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2K_RS31810	COG2340	Cysteine-rich secretory protein family
B2K_RS31820	COG4999	Histidine kinase
B2K_RS31820	COG3850	Histidine kinase
B2K_RS31820	COG3437	response regulator, receiver
B2K_RS31820	COG2205	protein histidine kinase activity
B2K_RS31835	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B2K_RS31855	COG0673	inositol 2-dehydrogenase activity
B2K_RS31860	COG0395	ABC-type sugar transport system, permease component
B2K_RS31865	COG1175	transmembrane transport
B2K_RS31870	COG1653	transport
B2K_RS31875	COG4753	response regulator
B2K_RS31875	COG2207	Transcriptional regulator
B2K_RS31880	COG2972	Histidine kinase
B2K_RS31900	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B2K_RS31915	COG0726	polysaccharide deacetylase
B2K_RS31915	COG1649	PFAM Uncharacterised BCR, COG1649
B2K_RS31925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B2K_RS31935	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B2K_RS31950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS31955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2K_RS31970	COG0778	Nitroreductase
B2K_RS31985	COG1876	peptidase activity
B2K_RS32005	COG0840	transmembrane signaling receptor activity
B2K_RS32010	COG4211	Belongs to the binding-protein-dependent transport system permease family
B2K_RS32030	COG2972	Histidine kinase
B2K_RS32035	COG2207	Transcriptional regulator
B2K_RS32075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B2K_RS32105	COG2198	Histidine kinase
B2K_RS32105	COG0784	Response regulator, receiver
B2K_RS32105	COG2205	protein histidine kinase activity
B2K_RS32110	COG0167	dihydroorotate dehydrogenase activity
B2K_RS32150	COG0670	Belongs to the BI1 family
B2K_RS32155	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
B2K_RS32165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2K_RS32170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS32175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS32180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B2K_RS32205	COG0003	Pfam Anion-transporting ATPase
B2K_RS32220	COG1605	Chorismate mutase
B2K_RS32220	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B2K_RS32230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2K_RS32235	COG0667	Aldo Keto reductase
B2K_RS32250	COG1979	alcohol dehydrogenase
B2K_RS32280	COG1881	PFAM PEBP family protein
B2K_RS32290	COG3209	COG3209 Rhs family protein
B2K_RS32320	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS32320	COG0604	alcohol dehydrogenase
B2K_RS32320	COG3321	synthase
B2K_RS32335	COG0693	protein deglycase activity
B2K_RS32340	COG1082	Xylose isomerase domain protein TIM barrel
B2K_RS32355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B2K_RS32390	COG0076	glutamate decarboxylase activity
B2K_RS32405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B2K_RS32410	COG1131	(ABC) transporter
B2K_RS32420	COG2188	Transcriptional regulator
B2K_RS32430	COG2222	sugar isomerase
B2K_RS32435	COG0531	amino acid
B2K_RS32455	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B2K_RS32475	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B2K_RS32480	COG2115	Belongs to the xylose isomerase family
B2K_RS32515	COG2972	Histidine kinase
B2K_RS32520	COG0395	ABC-type sugar transport system, permease component
B2K_RS32525	COG1175	transmembrane transport
B2K_RS32540	COG0667	Aldo Keto reductase
B2K_RS32560	COG0765	amino acid transport
B2K_RS32585	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
B2K_RS32610	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B2K_RS32630	COG5002	protein histidine kinase activity
B2K_RS32630	COG0784	Response regulator, receiver
B2K_RS32630	COG2198	Histidine kinase
B2K_RS32665	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B2K_RS32685	COG0084	hydrolase, TatD family'
B2K_RS32690	COG0463	Glycosyl transferase, family 2
B2K_RS32690	COG0457	Tetratricopeptide repeat
B2K_RS32695	COG0084	hydrolase, TatD family'
B2K_RS32705	COG3541	Predicted nucleotidyltransferase
B2K_RS32730	COG0459	protein refolding
B2K_RS32735	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B2K_RS32750	COG1177	transmembrane transport
B2K_RS32755	COG1176	ABC-type spermidine putrescine transport system, permease component I
B2K_RS32765	COG1132	(ABC) transporter
B2K_RS32770	COG1132	(ABC) transporter
B2K_RS32785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B2K_RS32790	COG0154	amidase activity
B2K_RS32800	COG2706	6-phosphogluconolactonase activity
B2K_RS32820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B2K_RS32830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B2K_RS32835	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B2K_RS32845	COG4677	pectinesterase activity
B2K_RS32865	COG0386	Belongs to the glutathione peroxidase family
B2K_RS32880	COG1172	Belongs to the binding-protein-dependent transport system permease family
B2K_RS32885	COG1129	ABC transporter
B2K_RS32890	COG1129	ABC transporter
B2K_RS32895	COG1349	DNA-binding transcription factor activity
B2K_RS32925	COG3706	GGDEF domain
B2K_RS32930	COG2514	catechol 2,3-dioxygenase activity
B2K_RS32935	COG2259	Doxx family
B2K_RS32945	COG2205	protein histidine kinase activity
B2K_RS32950	COG0745	RESPONSE REGULATOR receiver
B2K_RS32955	COG2311	Membrane
B2K_RS32975	COG4191	Histidine kinase
B2K_RS32990	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B2K_RS33000	COG1459	type II secretion system
B2K_RS33010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B2K_RS33040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B2K_RS33045	COG1523	belongs to the glycosyl hydrolase 13 family
B2K_RS33055	COG0753	catalase activity
B2K_RS33065	COG2197	response regulator
B2K_RS33070	COG4585	Histidine kinase
B2K_RS33075	COG3239	Fatty acid desaturase
B2K_RS33080	COG0824	Thioesterase
B2K_RS33085	COG3940	Belongs to the glycosyl hydrolase 43 family
B2K_RS33090	COG0438	transferase activity, transferring glycosyl groups
B2K_RS33105	COG2814	Major facilitator Superfamily
B2K_RS33170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B2K_RS33175	COG1597	lipid kinase activity
B2K_RS33185	COG4496	protein, YerC YecD
B2K_RS33195	COG1902	pentaerythritol trinitrate reductase activity
B2K_RS33200	COG2205	protein histidine kinase activity
B2K_RS33235	COG2207	Transcriptional regulator
B2K_RS33245	COG1595	DNA-templated transcription, initiation
B2K_RS33250	COG2261	transglycosylase associated protein
B2K_RS33280	COG1191	sigma factor activity
B2K_RS33290	COG1366	Belongs to the anti-sigma-factor antagonist family
B2K_RS33300	COG0783	Belongs to the Dps family
B2K_RS33305	COG1744	ABC transporter substrate-binding protein PnrA-like
B2K_RS33310	COG3845	ABC transporter
B2K_RS33315	COG4603	Belongs to the binding-protein-dependent transport system permease family
B2K_RS33320	COG1079	Belongs to the binding-protein-dependent transport system permease family
B2K_RS33325	COG2172	sigma factor antagonist activity
B2K_RS33345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B2K_RS33355	COG2205	protein histidine kinase activity
B2K_RS33355	COG3437	response regulator, receiver
B2K_RS33355	COG3850	Histidine kinase
B2K_RS33355	COG4999	Histidine kinase
B2K_RS33360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B2K_RS33370	COG2208	phosphoserine phosphatase activity
B2K_RS33385	COG1595	DNA-templated transcription, initiation
B2K_RS33395	COG1470	cell adhesion involved in biofilm formation
B2K_RS33405	COG3384	dioxygenase
B2K_RS33415	COG2378	regulation of single-species biofilm formation
B2K_RS33420	COG3118	belongs to the thioredoxin family
B2K_RS33440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B2K_RS33445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS33450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS33460	COG1819	glycosyl
B2K_RS33465	COG0151	Belongs to the GarS family
B2K_RS33480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B2K_RS33485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B2K_RS33490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B2K_RS33495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B2K_RS33500	COG0047	phosphoribosylformylglycinamidine synthase activity
B2K_RS33505	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B2K_RS33510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B2K_RS33515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B2K_RS33520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B2K_RS33525	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B2K_RS33540	COG3584	3D domain protein
B2K_RS33540	COG3583	domain protein
B2K_RS33585	COG0456	acetyltransferase
B2K_RS33590	COG1214	PFAM Peptidase M22, glycoprotease
B2K_RS33595	COG0802	atpase or kinase
B2K_RS33600	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B2K_RS33615	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B2K_RS33635	COG3285	dna ligase
B2K_RS33635	COG1793	dna ligase
B2K_RS33640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B2K_RS33645	COG0697	spore germination
B2K_RS33670	COG0739	heme binding
B2K_RS33680	COG0546	phosphoglycolate phosphatase activity
B2K_RS33700	COG4533	DNA binding
B2K_RS33715	COG0493	'glutamate synthase
B2K_RS33720	COG0067	glutamate synthase
B2K_RS33720	COG0069	glutamate synthase activity
B2K_RS33720	COG0070	glutamate synthase
B2K_RS33725	COG5002	protein histidine kinase activity
B2K_RS33730	COG1435	thymidine kinase activity
B2K_RS33735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B2K_RS33740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2K_RS33755	COG1595	DNA-templated transcription, initiation
B2K_RS33760	COG0737	Belongs to the 5'-nucleotidase family
B2K_RS33770	COG1233	COG1233 Phytoene dehydrogenase and related
B2K_RS33775	COG0693	protein deglycase activity
B2K_RS33800	COG0366	Alpha amylase catalytic
B2K_RS33805	COG1418	mRNA catabolic process
B2K_RS33815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B2K_RS33825	COG2201	protein-glutamate methylesterase activity
B2K_RS33850	COG0509	glycine decarboxylation via glycine cleavage system
B2K_RS33855	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B2K_RS33860	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B2K_RS33865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B2K_RS33885	COG5634	Uncharacterized conserved protein (DUF2278)
B2K_RS33900	COG1609	Transcriptional regulator
B2K_RS33910	COG3858	chitin binding
B2K_RS33920	COG1968	undecaprenyl-diphosphatase activity
B2K_RS33925	COG0598	Magnesium transport protein CorA
B2K_RS33930	COG1376	ErfK ybiS ycfS ynhG family protein
B2K_RS33935	COG1309	transcriptional regulator
B2K_RS33940	COG3326	Membrane
B2K_RS33955	COG1295	ribonuclease BN
B2K_RS33965	COG5002	protein histidine kinase activity
B2K_RS33990	COG1609	Transcriptional regulator
B2K_RS33990	COG2207	Transcriptional regulator
B2K_RS34000	COG0395	ABC-type sugar transport system, permease component
B2K_RS34005	COG4209	transmembrane transport
B2K_RS34025	COG1012	belongs to the aldehyde dehydrogenase family
B2K_RS34030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B2K_RS34040	COG1012	belongs to the aldehyde dehydrogenase family
B2K_RS34045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B2K_RS34050	COG1027	Aspartate ammonia-lyase
B2K_RS34055	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B2K_RS34060	COG2707	UPF0756 membrane protein
B2K_RS34065	COG4191	Histidine kinase
B2K_RS34090	COG3829	transcription factor binding
B2K_RS34105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B2K_RS34110	COG0531	amino acid
B2K_RS34120	COG2235	arginine
B2K_RS34150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B2K_RS34160	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B2K_RS34165	COG5662	AntiSigma factor
B2K_RS34170	COG1595	DNA-templated transcription, initiation
B2K_RS34175	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B2K_RS34180	COG5002	protein histidine kinase activity
B2K_RS34180	COG0784	Response regulator, receiver
B2K_RS34180	COG2205	protein histidine kinase activity
B2K_RS34195	COG0628	permease
B2K_RS34200	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS34290	COG0726	polysaccharide deacetylase
B2K_RS34295	COG2194	sulfuric ester hydrolase activity
B2K_RS34305	COG0489	protein tyrosine kinase activity
B2K_RS34310	COG0860	N-Acetylmuramoyl-L-alanine amidase
B2K_RS34315	COG2046	Belongs to the sulfate adenylyltransferase family
B2K_RS34320	COG0175	sulfate reduction
B2K_RS34325	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B2K_RS34330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B2K_RS34335	COG0101	tRNA pseudouridine synthase activity
B2K_RS34340	COG0203	ribosomal protein L17
B2K_RS34345	COG0202	RNA polymerase activity
B2K_RS34350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B2K_RS34355	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B2K_RS34360	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B2K_RS34365	COG2163	COG2163 Ribosomal protein L14E L6E L27E
B2K_RS34370	COG0024	Methionine aminopeptidase
B2K_RS34375	COG0563	adenylate kinase activity
B2K_RS34380	COG0201	protein transport
B2K_RS34385	COG0200	Binds to the 23S rRNA
B2K_RS34390	COG1841	ribosomal large subunit assembly
B2K_RS34395	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B2K_RS34400	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B2K_RS34405	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B2K_RS34410	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B2K_RS34415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B2K_RS34420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B2K_RS34425	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B2K_RS34430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B2K_RS34435	COG0255	Belongs to the universal ribosomal protein uL29 family
B2K_RS34440	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B2K_RS34445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B2K_RS34450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B2K_RS34455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B2K_RS34460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B2K_RS34465	COG0089	rRNA binding
B2K_RS34470	COG0088	Forms part of the polypeptide exit tunnel
B2K_RS34475	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B2K_RS34480	COG0051	transcription antitermination factor activity, RNA binding
B2K_RS34485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B2K_RS34490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B2K_RS34495	COG0049	tRNA binding
B2K_RS34500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B2K_RS34505	COG1358	cellular component organization or biogenesis
B2K_RS34510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B2K_RS34515	COG0085	RNA polymerase activity
B2K_RS34520	COG2813	Specifically methylates the guanine in position
B2K_RS34525	COG0222	ribosome binding
B2K_RS34535	COG0081	regulation of translation
B2K_RS34540	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B2K_RS34545	COG0250	Participates in transcription elongation, termination and antitermination
B2K_RS34550	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B2K_RS34560	COG3688	RNA-binding protein containing a PIN domain
B2K_RS34565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B2K_RS34570	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
B2K_RS34575	COG0215	cysteine-tRNA ligase activity
B2K_RS34580	COG1045	serine acetyltransferase
B2K_RS34585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B2K_RS34595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B2K_RS34600	COG4956	integral membrane protein (PIN domain superfamily)
B2K_RS34605	COG1183	phosphatidylcholine synthase activity
B2K_RS34610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B2K_RS34615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B2K_RS34620	COG0542	response to heat
B2K_RS34625	COG3869	Catalyzes the specific phosphorylation of arginine residues in
B2K_RS34630	COG3880	PFAM UvrB UvrC protein
B2K_RS34635	COG4463	regulation of RNA biosynthetic process
B2K_RS34660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B2K_RS34665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B2K_RS34670	COG1396	sequence-specific DNA binding
B2K_RS34675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B2K_RS34680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B2K_RS34685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B2K_RS34690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B2K_RS34695	COG0512	Glutamine amidotransferase of anthranilate synthase
B2K_RS34700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B2K_RS34705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B2K_RS34710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B2K_RS34715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B2K_RS34720	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B2K_RS34725	COG0157	Belongs to the NadC ModD family
B2K_RS34730	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B2K_RS34735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B2K_RS34740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B2K_RS34750	COG0037	tRNA processing
B2K_RS34755	COG0515	serine threonine protein kinase
B2K_RS34770	COG2208	phosphoserine phosphatase activity
B2K_RS34780	COG1098	S1 RNA binding domain
B2K_RS34800	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B2K_RS34810	COG3956	TIGRFAM MazG family protein
B2K_RS34815	COG2244	polysaccharide biosynthetic process
B2K_RS34820	COG2002	toxin-antitoxin pair type II binding
B2K_RS34830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B2K_RS34845	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B2K_RS34850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B2K_RS34855	COG2088	sporulation resulting in formation of a cellular spore
B2K_RS34860	COG0251	oxidation-reduction process
B2K_RS34865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B2K_RS34880	COG4466	Protein conserved in bacteria
B2K_RS34890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B2K_RS34900	COG3584	3D domain protein
B2K_RS34900	COG3583	domain protein
B2K_RS34905	COG0084	hydrolase, TatD family'
B2K_RS34910	COG1078	dGTPase activity
B2K_RS34915	COG2002	toxin-antitoxin pair type II binding
B2K_RS34920	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B2K_RS34925	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B2K_RS34930	COG4467	Involved in initiation control of chromosome replication
B2K_RS34935	COG1774	PSP1 C-terminal conserved region
B2K_RS34940	COG0470	DNA polymerase III
B2K_RS34945	COG1728	Protein conserved in bacteria
B2K_RS34950	COG3870	Protein conserved in bacteria
B2K_RS34955	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B2K_RS34960	COG1982	Orn Lys Arg decarboxylase major
B2K_RS35000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B2K_RS35005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B2K_RS35010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B2K_RS35015	COG3852	Histidine kinase
B2K_RS35025	COG0254	rRNA binding
B2K_RS35035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B2K_RS35040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B2K_RS35045	COG0191	fructose-bisphosphate aldolase activity
B2K_RS35055	COG0504	CTP synthase activity
B2K_RS35060	COG3343	RNA polymerase activity
B2K_RS35065	COG1404	Belongs to the peptidase S8 family
B2K_RS35075	COG2207	Transcriptional regulator
B2K_RS35075	COG1917	Cupin 2, conserved barrel domain protein
B2K_RS35080	COG1408	metallophosphoesterase
B2K_RS35100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2K_RS35110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B2K_RS35135	COG0415	Belongs to the DNA photolyase family
B2K_RS35145	COG2329	Antibiotic biosynthesis monooxygenase
B2K_RS35170	COG2154	pterin-4-alpha-carbinolamine dehydratase
B2K_RS35185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B2K_RS35190	COG5002	protein histidine kinase activity
B2K_RS35210	COG2308	Evidence 4 Homologs of previously reported genes of
B2K_RS35220	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B2K_RS35225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B2K_RS35230	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B2K_RS35240	COG5002	protein histidine kinase activity
B2K_RS35245	COG0745	RESPONSE REGULATOR receiver
B2K_RS35250	COG1187	pseudouridine synthase activity
B2K_RS35265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2K_RS35270	COG0477	Major facilitator Superfamily
B2K_RS35280	COG2814	Major facilitator Superfamily
B2K_RS35325	COG0772	Belongs to the SEDS family
B2K_RS35340	COG0778	Nitroreductase
B2K_RS35360	COG2814	Major facilitator Superfamily
B2K_RS35370	COG1566	PFAM secretion protein HlyD family protein
B2K_RS35375	COG1846	Transcriptional regulator
B2K_RS35390	COG2133	pyrroloquinoline quinone binding
B2K_RS35395	COG2233	PERMEase
B2K_RS35400	COG0395	ABC-type sugar transport system, permease component
B2K_RS35410	COG1653	transport
B2K_RS35415	COG2207	Transcriptional regulator
B2K_RS35415	COG4753	response regulator
B2K_RS35425	COG3275	phosphorelay sensor kinase activity
B2K_RS35430	COG0783	Belongs to the Dps family
B2K_RS35435	COG4326	sporulation control protein
B2K_RS35445	COG3386	PFAM SMP-30 Gluconolaconase
B2K_RS35450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B2K_RS35460	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B2K_RS35465	COG0187	DNA topoisomerase II activity
B2K_RS35480	COG1396	sequence-specific DNA binding
B2K_RS35485	COG2226	methyltransferase
B2K_RS35495	COG2072	flavoprotein involved in K transport
B2K_RS35515	COG1801	Protein of unknown function DUF72
B2K_RS35520	COG0442	prolyl-tRNA aminoacylation
B2K_RS35525	COG2217	Heavy metal translocating P-type atpase
B2K_RS35550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B2K_RS35570	COG2249	NAD(P)H dehydrogenase (quinone) activity
B2K_RS35580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B2K_RS35590	COG1012	belongs to the aldehyde dehydrogenase family
B2K_RS35595	COG0506	proline dehydrogenase activity
B2K_RS35600	COG0477	Major facilitator Superfamily
B2K_RS35605	COG2204	response regulator
B2K_RS35620	COG4585	Histidine kinase
B2K_RS35645	COG0398	Pfam SNARE associated Golgi protein
B2K_RS35665	COG1132	(ABC) transporter
B2K_RS35690	COG1573	uracil-dna glycosylase
B2K_RS35695	COG4191	Histidine kinase
B2K_RS35720	COG1132	(ABC) transporter
B2K_RS35725	COG1132	(ABC) transporter
B2K_RS35735	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
B2K_RS35740	COG0783	Belongs to the Dps family
B2K_RS35745	COG0735	belongs to the Fur family
B2K_RS35755	COG0735	belongs to the Fur family
B2K_RS35780	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B2K_RS35785	COG0477	Major facilitator Superfamily
B2K_RS35800	COG0395	ABC-type sugar transport system, permease component
B2K_RS35805	COG4209	transmembrane transport
B2K_RS35810	COG1653	transport
B2K_RS35815	COG2207	Transcriptional regulator
B2K_RS35825	COG5002	protein histidine kinase activity
B2K_RS35830	COG0745	RESPONSE REGULATOR receiver
B2K_RS35840	COG1120	ATPase activity
B2K_RS35845	COG3300	MHYT domain
B2K_RS35845	COG5001	Diguanylate cyclase
B2K_RS35850	COG0840	transmembrane signaling receptor activity
B2K_RS35870	COG1278	Cold shock
B2K_RS35875	COG0840	transmembrane signaling receptor activity
B2K_RS35880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B2K_RS35885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B2K_RS35890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B2K_RS35895	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B2K_RS35900	COG4607	ABC-type enterochelin transport system periplasmic component
B2K_RS35905	COG4604	ABC transporter, ATP-binding protein
B2K_RS35910	COG4605	iron ion homeostasis
B2K_RS35915	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2K_RS35920	COG1252	NADH dehydrogenase
B2K_RS35935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B2K_RS35940	COG1653	transport
B2K_RS35960	COG1028	Short-chain dehydrogenase reductase Sdr
B2K_RS35970	COG0840	transmembrane signaling receptor activity
B2K_RS35970	COG3290	protein histidine kinase activity
B2K_RS35995	COG1131	(ABC) transporter
B2K_RS36000	COG2755	lipolytic protein G-D-S-L family
B2K_RS36010	COG0697	spore germination
B2K_RS36020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B2K_RS36025	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B2K_RS36040	COG0640	Transcriptional regulator
B2K_RS36045	COG3832	glyoxalase III activity
B2K_RS36070	COG0673	inositol 2-dehydrogenase activity
B2K_RS36080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B2K_RS36085	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
B2K_RS36090	COG1733	regulation of RNA biosynthetic process
B2K_RS36095	COG0300	oxidoreductase activity
B2K_RS36100	COG0753	catalase activity
B2K_RS36105	COG0561	phosphatase activity
B2K_RS36120	COG1126	abc transporter atp-binding protein
B2K_RS36125	COG0765	amino acid transport
B2K_RS36130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2K_RS36135	COG0398	Pfam SNARE associated Golgi protein
B2K_RS36140	COG0398	Pfam SNARE associated Golgi protein
B2K_RS36150	COG2966	Psort location CytoplasmicMembrane, score
B2K_RS36155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B2K_RS36160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2K_RS36160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2K_RS36180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B2K_RS36190	COG1733	regulation of RNA biosynthetic process
B2K_RS36195	COG2814	Major facilitator Superfamily
B2K_RS36200	COG0656	L-ascorbic acid biosynthetic process
B2K_RS36210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B2K_RS36215	COG3104	oligopeptide transport
B2K_RS36220	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B2K_RS36225	COG2814	Major facilitator Superfamily
B2K_RS36230	COG0322	excinuclease ABC activity
B2K_RS36235	COG2824	Alkylphosphonate utilization operon protein PhnA
B2K_RS36240	COG1309	transcriptional regulator
B2K_RS36245	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B2K_RS36255	COG3866	Pectate lyase
B2K_RS36260	COG3708	Transcriptional regulator
B2K_RS36265	COG2378	regulation of single-species biofilm formation
B2K_RS36275	COG0513	Belongs to the DEAD box helicase family
B2K_RS36280	COG0783	Belongs to the Dps family
B2K_RS36285	COG2267	carboxylic ester hydrolase activity
B2K_RS36305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2K_RS36315	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B2K_RS36330	COG5002	protein histidine kinase activity
B2K_RS36335	COG0745	RESPONSE REGULATOR receiver
B2K_RS36340	COG0741	lytic transglycosylase activity
B2K_RS36340	COG0739	heme binding
B2K_RS36340	COG1196	nuclear chromosome segregation
B2K_RS36355	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B2K_RS36360	COG0305	Participates in initiation and elongation during chromosome replication
B2K_RS36370	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
B2K_RS36385	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B2K_RS36385	COG0517	IMP dehydrogenase activity
B2K_RS36390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B2K_RS36395	COG0629	single-stranded DNA binding
B2K_RS36400	COG0360	Binds together with S18 to 16S ribosomal RNA
B2K_RS36420	COG4481	Protein conserved in bacteria
B2K_RS36425	COG0668	transmembrane transport
B2K_RS36445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B2K_RS36450	COG1475	DNA binding
B2K_RS36455	COG1192	Involved in chromosome partitioning
B2K_RS36460	COG1475	DNA binding
B2K_RS36465	COG0357	Ribosomal RNA small subunit methyltransferase G
B2K_RS36470	COG0445	tRNA wobble uridine modification
B2K_RS36475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B2K_RS36480	COG1847	R3H domain protein
B2K_RS36485	COG0706	membrane insertase activity
B2K_RS36490	COG0594	ribonuclease P activity
B2K_RS36510	COG1396	sequence-specific DNA binding
B2K_RS36520	COG2207	Transcriptional regulator
B2K_RS36520	COG1609	Transcriptional regulator
B2K_RS36550	COG3693	PFAM glycoside hydrolase, family 10
B2K_RS36605	COG3266	domain, Protein
B2K_RS36605	COG1361	Conserved repeat domain
B2K_RS36605	COG2911	Protein conserved in bacteria
B2K_RS36640	COG0419	ATPase involved in DNA repair
B2K_RS36650	COG3733	amine oxidase