locus-tag	class	description
KNP414_RS00035	COG0592	DNA-directed DNA polymerase activity
KNP414_RS00040	COG2501	S4 domain
KNP414_RS00045	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KNP414_RS00055	COG0187	DNA topoisomerase II activity
KNP414_RS00060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNP414_RS00085	COG0517	IMP dehydrogenase activity
KNP414_RS00085	COG0516	GMP reductase activity
KNP414_RS00090	COG1686	Belongs to the peptidase S11 family
KNP414_RS00105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KNP414_RS00135	COG3973	AAA domain
KNP414_RS00140	COG0024	Methionine aminopeptidase
KNP414_RS00165	COG0586	Pfam SNARE associated Golgi protein
KNP414_RS00170	COG0590	tRNA wobble adenosine to inosine editing
KNP414_RS00185	COG0012	GTP binding
KNP414_RS00190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KNP414_RS00195	COG2890	protein-(glutamine-N5) methyltransferase activity
KNP414_RS00205	COG0009	L-threonylcarbamoyladenylate synthase
KNP414_RS00210	COG1971	Probably functions as a manganese efflux pump
KNP414_RS00220	COG0698	ribose 5-phosphate isomerase
KNP414_RS00225	COG4475	Protein of unknown function (DUF436)
KNP414_RS00230	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KNP414_RS00235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KNP414_RS00240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KNP414_RS00255	COG0356	it plays a direct role in the translocation of protons across the membrane
KNP414_RS00260	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNP414_RS00265	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KNP414_RS00270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNP414_RS00275	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KNP414_RS00280	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KNP414_RS00285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KNP414_RS00290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KNP414_RS00295	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNP414_RS00300	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNP414_RS00305	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNP414_RS00310	COG0649	NAD binding
KNP414_RS00315	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KNP414_RS00325	COG0839	Belongs to the complex I subunit 6 family
KNP414_RS00330	COG0713	ATP synthesis coupled electron transport
KNP414_RS00335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KNP414_RS00340	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNP414_RS00345	COG1007	ATP synthesis coupled electron transport
KNP414_RS00350	COG1846	Transcriptional regulator
KNP414_RS00360	COG4836	Membrane
KNP414_RS00365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNP414_RS00370	COG2385	sporulation resulting in formation of a cellular spore
KNP414_RS00375	COG0739	heme binding
KNP414_RS00380	COG1609	Transcriptional regulator
KNP414_RS00390	COG4786	Flagellar basal body rod
KNP414_RS00410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KNP414_RS00415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNP414_RS00430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNP414_RS00455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KNP414_RS00465	COG4585	Histidine kinase
KNP414_RS00480	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KNP414_RS00485	COG1040	competence protein
KNP414_RS00505	COG4786	Flagellar basal body rod
KNP414_RS00505	COG1256	bacterial-type flagellum assembly
KNP414_RS00510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KNP414_RS00520	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KNP414_RS00525	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KNP414_RS00530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KNP414_RS00535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KNP414_RS00545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KNP414_RS00550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KNP414_RS00560	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KNP414_RS00575	COG1278	Cold shock
KNP414_RS00585	COG0653	protein targeting
KNP414_RS00595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KNP414_RS00600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNP414_RS00605	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KNP414_RS00610	COG3383	formate dehydrogenase (NAD+) activity
KNP414_RS00615	COG5609	conserved protein (DUF2294)
KNP414_RS00620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KNP414_RS00625	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KNP414_RS00630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KNP414_RS00635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KNP414_RS00640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KNP414_RS00645	COG0137	argininosuccinate synthase activity
KNP414_RS00650	COG0165	Argininosuccinate lyase
KNP414_RS00655	COG2720	vancomycin resistance protein
KNP414_RS00660	COG2884	Cell division ATP-binding protein ftsE
KNP414_RS00665	COG2177	Part of the ABC transporter FtsEX involved in
KNP414_RS00670	COG0739	heme binding
KNP414_RS00675	COG3409	Peptidoglycan-binding domain 1 protein
KNP414_RS00675	COG0793	Belongs to the peptidase S41A family
KNP414_RS00685	COG1360	Flagellar Motor Protein
KNP414_RS00695	COG0556	nucleotide-excision repair
KNP414_RS00700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KNP414_RS00760	COG0826	peptidase U32
KNP414_RS00770	COG1131	(ABC) transporter
KNP414_RS00790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KNP414_RS00825	COG1403	HNH endonuclease
KNP414_RS00835	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KNP414_RS00840	COG0210	DNA helicase
KNP414_RS00845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KNP414_RS00900	COG2508	Transcriptional regulator
KNP414_RS00905	COG3842	ATPase activity
KNP414_RS00910	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KNP414_RS00915	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KNP414_RS00920	COG0546	phosphoglycolate phosphatase activity
KNP414_RS00925	COG0110	maltose O-acetyltransferase activity
KNP414_RS00930	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KNP414_RS00935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KNP414_RS00940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KNP414_RS00945	COG0131	Imidazoleglycerol-phosphate dehydratase
KNP414_RS00950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KNP414_RS00955	COG0107	imidazoleglycerol-phosphate synthase activity
KNP414_RS00960	COG0140	phosphoribosyl-ATP diphosphatase activity
KNP414_RS00960	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KNP414_RS00965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KNP414_RS00975	COG0457	Tetratricopeptide repeat
KNP414_RS00985	COG3227	Zinc metalloprotease (Elastase)
KNP414_RS00995	COG1940	carbohydrate kinase activity
KNP414_RS01000	COG1660	Displays ATPase and GTPase activities
KNP414_RS01005	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KNP414_RS01010	COG1481	regulation of sporulation
KNP414_RS01015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KNP414_RS01030	COG0740	serine-type endopeptidase activity
KNP414_RS01045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KNP414_RS01050	COG0126	phosphoglycerate kinase activity
KNP414_RS01055	COG0149	triose-phosphate isomerase activity
KNP414_RS01060	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KNP414_RS01065	COG0148	phosphopyruvate hydratase activity
KNP414_RS01075	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KNP414_RS01080	COG2267	carboxylic ester hydrolase activity
KNP414_RS01085	COG0557	exoribonuclease II activity
KNP414_RS01095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KNP414_RS01120	COG1309	transcriptional regulator
KNP414_RS01140	COG0306	phosphate transporter
KNP414_RS01145	COG0531	amino acid
KNP414_RS01150	COG0583	DNA-binding transcription factor activity
KNP414_RS01155	COG2822	iron ion transport
KNP414_RS01160	COG2837	iron assimilation
KNP414_RS01165	COG0672	)-iron permease
KNP414_RS01170	COG1404	Belongs to the peptidase S8 family
KNP414_RS01270	COG3711	transcriptional antiterminator
KNP414_RS01275	COG1263	PTS System
KNP414_RS01275	COG2190	(PTS) system
KNP414_RS01275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNP414_RS01295	COG3729	General stress protein
KNP414_RS01320	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KNP414_RS01325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KNP414_RS01335	COG3858	chitin binding
KNP414_RS01335	COG1388	LysM domain
KNP414_RS01355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KNP414_RS01365	COG0322	excinuclease ABC activity
KNP414_RS01370	COG0179	Fumarylacetoacetate (FAA) hydrolase
KNP414_RS01385	COG3339	Conserved Protein
KNP414_RS01395	COG1278	Cold shock
KNP414_RS01420	COG2972	Histidine kinase
KNP414_RS01425	COG2207	Transcriptional regulator
KNP414_RS01425	COG4753	response regulator
KNP414_RS01425	COG2207	Transcriptional regulator
KNP414_RS01425	COG4753	response regulator
KNP414_RS01430	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS01435	COG4209	transmembrane transport
KNP414_RS01440	COG0395	ABC-type sugar transport system, permease component
KNP414_RS01445	COG1653	transport
KNP414_RS01460	COG4608	Belongs to the ABC transporter superfamily
KNP414_RS01465	COG0444	Belongs to the ABC transporter superfamily
KNP414_RS01470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNP414_RS01475	COG0601	transmembrane transport
KNP414_RS01480	COG0747	negative chemotaxis
KNP414_RS01495	COG3706	GGDEF domain
KNP414_RS01495	COG5001	Diguanylate cyclase
KNP414_RS01495	COG4251	negative regulation of phosphorylation
KNP414_RS01495	COG2203	Gaf domain
KNP414_RS01500	COG0515	serine threonine protein kinase
KNP414_RS01530	COG0640	Transcriptional regulator
KNP414_RS01535	COG2207	Transcriptional regulator
KNP414_RS01540	COG0667	Aldo Keto reductase
KNP414_RS01545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNP414_RS01550	COG1309	transcriptional regulator
KNP414_RS01555	COG1368	sulfuric ester hydrolase activity
KNP414_RS01565	COG3711	transcriptional antiterminator
KNP414_RS01575	COG0246	Mannitol dehydrogenase
KNP414_RS01585	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KNP414_RS01605	COG1802	Transcriptional regulator
KNP414_RS01615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNP414_RS01635	COG5297	Belongs to the glycosyl hydrolase family 6
KNP414_RS01635	COG4733	cellulase activity
KNP414_RS01650	COG1472	Belongs to the glycosyl hydrolase 3 family
KNP414_RS01655	COG0784	Response regulator, receiver
KNP414_RS01655	COG2205	protein histidine kinase activity
KNP414_RS01655	COG2198	Histidine kinase
KNP414_RS01665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KNP414_RS01675	COG0745	RESPONSE REGULATOR receiver
KNP414_RS01680	COG2197	response regulator
KNP414_RS01705	COG0778	Nitroreductase
KNP414_RS01710	COG2972	Histidine kinase
KNP414_RS01715	COG2207	Transcriptional regulator
KNP414_RS01715	COG4753	response regulator
KNP414_RS01715	COG2207	Transcriptional regulator
KNP414_RS01715	COG4753	response regulator
KNP414_RS01720	COG0697	spore germination
KNP414_RS01725	COG2814	Major facilitator Superfamily
KNP414_RS01760	COG1361	Conserved repeat domain
KNP414_RS01785	COG2329	Antibiotic biosynthesis monooxygenase
KNP414_RS01790	COG4209	transmembrane transport
KNP414_RS01795	COG0395	ABC-type sugar transport system, permease component
KNP414_RS01805	COG1501	Belongs to the glycosyl hydrolase 31 family
KNP414_RS01815	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS01855	COG1674	ftsk spoiiie
KNP414_RS01925	COG2911	Protein conserved in bacteria
KNP414_RS01925	COG1361	Conserved repeat domain
KNP414_RS01925	COG3266	domain, Protein
KNP414_RS01930	COG3266	domain, Protein
KNP414_RS01930	COG1361	Conserved repeat domain
KNP414_RS01930	COG2911	Protein conserved in bacteria
KNP414_RS01950	COG0706	membrane insertase activity
KNP414_RS01970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KNP414_RS01975	COG2972	Histidine kinase
KNP414_RS01980	COG4753	response regulator
KNP414_RS01980	COG2207	Transcriptional regulator
KNP414_RS01985	COG2201	protein-glutamate methylesterase activity
KNP414_RS02025	COG0861	Integral membrane protein TerC family
KNP414_RS02060	COG1595	DNA-templated transcription, initiation
KNP414_RS02075	COG0778	Nitroreductase
KNP414_RS02090	COG1192	Involved in chromosome partitioning
KNP414_RS02105	COG0514	ATP-dependent DNA helicase (RecQ)
KNP414_RS02110	COG3341	Caulimovirus viroplasmin
KNP414_RS02110	COG0328	RNA-DNA hybrid ribonuclease activity
KNP414_RS02115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KNP414_RS02120	COG0400	carboxylic ester hydrolase activity
KNP414_RS02125	COG0346	lactoylglutathione lyase activity
KNP414_RS02130	COG2259	Doxx family
KNP414_RS02135	COG1846	Transcriptional regulator
KNP414_RS02140	COG2378	regulation of single-species biofilm formation
KNP414_RS02145	COG2309	aminopeptidase activity
KNP414_RS02150	COG0733	neurotransmitter:sodium symporter activity
KNP414_RS02155	COG3300	MHYT domain
KNP414_RS02155	COG5001	Diguanylate cyclase
KNP414_RS02160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KNP414_RS02170	COG1131	(ABC) transporter
KNP414_RS02180	COG5002	protein histidine kinase activity
KNP414_RS02180	COG5000	phosphorelay sensor kinase activity
KNP414_RS02185	COG0745	RESPONSE REGULATOR receiver
KNP414_RS02190	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS02190	COG4977	sequence-specific DNA binding
KNP414_RS02205	COG1811	Na channel or pump
KNP414_RS02210	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KNP414_RS02215	COG1132	(ABC) transporter
KNP414_RS02220	COG1132	(ABC) transporter
KNP414_RS02235	COG1413	lyase activity
KNP414_RS02245	COG0194	GDP metabolic process
KNP414_RS02280	COG3336	cytochrome c oxidase
KNP414_RS02300	COG0791	NLP P60 protein
KNP414_RS02300	COG0741	lytic transglycosylase activity
KNP414_RS02305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNP414_RS02315	COG1733	regulation of RNA biosynthetic process
KNP414_RS02330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KNP414_RS02355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KNP414_RS02360	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS02365	COG0477	Major facilitator Superfamily
KNP414_RS02375	COG2081	HI0933 family
KNP414_RS02385	COG0840	transmembrane signaling receptor activity
KNP414_RS02390	COG1253	flavin adenine dinucleotide binding
KNP414_RS02410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KNP414_RS02415	COG3546	catalase activity
KNP414_RS02425	COG0736	holo-[acyl-carrier-protein] synthase activity
KNP414_RS02440	COG2207	Transcriptional regulator
KNP414_RS02450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNP414_RS02460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KNP414_RS02485	COG3557	Belongs to the UPF0374 family
KNP414_RS02515	COG0302	gtp cyclohydrolase
KNP414_RS02520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KNP414_RS02530	COG1414	Transcriptional regulator
KNP414_RS02535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KNP414_RS02555	COG4294	response to UV
KNP414_RS02565	COG0483	inositol monophosphate 1-phosphatase activity
KNP414_RS02675	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KNP414_RS02690	COG4106	trans-aconitate 2-methyltransferase activity
KNP414_RS02695	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS02700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNP414_RS02705	COG0800	Aldolase
KNP414_RS02720	COG0067	glutamate synthase
KNP414_RS02720	COG0069	glutamate synthase activity
KNP414_RS02720	COG0070	glutamate synthase
KNP414_RS02725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KNP414_RS02730	COG0384	phenazine biosynthesis protein PhzF
KNP414_RS02735	COG1316	TRANSCRIPTIONal
KNP414_RS02740	COG4555	ABC transporter
KNP414_RS02755	COG2197	response regulator
KNP414_RS02760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KNP414_RS02765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNP414_RS02770	COG2706	6-phosphogluconolactonase activity
KNP414_RS02775	COG0726	polysaccharide deacetylase
KNP414_RS02780	COG0714	Associated with various cellular activities
KNP414_RS02790	COG1305	Transglutaminase-like
KNP414_RS02805	COG0519	Catalyzes the synthesis of GMP from XMP
KNP414_RS02805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KNP414_RS02810	COG2252	PERMEase
KNP414_RS02815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KNP414_RS02820	COG2326	polyphosphate kinase activity
KNP414_RS02825	COG0488	(ABC) transporter
KNP414_RS02830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KNP414_RS02835	COG0315	cyclic pyranopterin monophosphate synthase activity
KNP414_RS02840	COG0521	Mo-molybdopterin cofactor biosynthetic process
KNP414_RS02855	COG0805	protein transport
KNP414_RS02860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KNP414_RS02865	COG0459	protein refolding
KNP414_RS02875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNP414_RS02905	COG0297	glycogen (starch) synthase activity
KNP414_RS02905	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS02920	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KNP414_RS02925	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KNP414_RS02945	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KNP414_RS02950	COG0517	IMP dehydrogenase activity
KNP414_RS02950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KNP414_RS02955	COG0463	Glycosyl transferase, family 2
KNP414_RS02975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KNP414_RS02990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNP414_RS02995	COG0864	Transcriptional regulator
KNP414_RS03000	COG2337	Toxic component of a toxin-antitoxin (TA) module
KNP414_RS03005	COG2183	response to ionizing radiation
KNP414_RS03035	COG3871	stress protein (general stress protein 26)
KNP414_RS03040	COG3546	catalase activity
KNP414_RS03055	COG0584	glycerophosphoryl diester phosphodiesterase
KNP414_RS03060	COG1361	Conserved repeat domain
KNP414_RS03070	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KNP414_RS03075	COG0788	formyltetrahydrofolate deformylase activity
KNP414_RS03080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNP414_RS03085	COG2146	nitrite reductase [NAD(P)H] activity
KNP414_RS03095	COG3123	guanosine phosphorylase activity
KNP414_RS03105	COG0166	Belongs to the GPI family
KNP414_RS03110	COG1739	Uncharacterized protein family UPF0029
KNP414_RS03115	COG1309	transcriptional regulator
KNP414_RS03120	COG0432	Pfam Uncharacterised protein family UPF0047
KNP414_RS03125	COG4840	Belongs to the UPF0435 family
KNP414_RS03135	COG1294	oxidase, subunit
KNP414_RS03140	COG1271	oxidase subunit
KNP414_RS03160	COG0517	IMP dehydrogenase activity
KNP414_RS03160	COG0516	GMP reductase activity
KNP414_RS03165	COG1686	Belongs to the peptidase S11 family
KNP414_RS03210	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNP414_RS03225	COG2201	protein-glutamate methylesterase activity
KNP414_RS03230	COG0745	RESPONSE REGULATOR receiver
KNP414_RS03235	COG2205	protein histidine kinase activity
KNP414_RS03250	COG1486	melibiose metabolic process
KNP414_RS03255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNP414_RS03260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNP414_RS03260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNP414_RS03280	COG1051	belongs to the nudix hydrolase family
KNP414_RS03290	COG1233	COG1233 Phytoene dehydrogenase and related
KNP414_RS03295	COG1846	Transcriptional regulator
KNP414_RS03315	COG3401	FG-GAP repeat protein
KNP414_RS03325	COG0564	pseudouridine synthase activity
KNP414_RS03330	COG3773	Cell wall hydrolase
KNP414_RS03335	COG1131	(ABC) transporter
KNP414_RS03360	COG1482	cell wall glycoprotein biosynthetic process
KNP414_RS03365	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KNP414_RS03375	COG1242	4 iron, 4 sulfur cluster binding
KNP414_RS03390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KNP414_RS03395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KNP414_RS03400	COG0671	phosphoesterase, PA-phosphatase related
KNP414_RS03405	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS03410	COG1215	transferase activity, transferring glycosyl groups
KNP414_RS03420	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KNP414_RS03425	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KNP414_RS03445	COG0028	Belongs to the TPP enzyme family
KNP414_RS03450	COG0440	acetolactate synthase activity
KNP414_RS03455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KNP414_RS03460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KNP414_RS03480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNP414_RS03490	COG0473	3-isopropylmalate dehydrogenase activity
KNP414_RS03495	COG0450	alkyl hydroperoxide reductase
KNP414_RS03500	COG0509	glycine decarboxylation via glycine cleavage system
KNP414_RS03515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KNP414_RS03520	COG1543	Belongs to the glycosyl hydrolase 57 family
KNP414_RS03540	COG1191	sigma factor activity
KNP414_RS03570	COG0667	Aldo Keto reductase
KNP414_RS03575	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KNP414_RS03585	COG0673	inositol 2-dehydrogenase activity
KNP414_RS03590	COG4191	Histidine kinase
KNP414_RS03595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KNP414_RS03630	COG0840	transmembrane signaling receptor activity
KNP414_RS03665	COG0745	RESPONSE REGULATOR receiver
KNP414_RS03700	COG2814	Major facilitator Superfamily
KNP414_RS03705	COG2207	Transcriptional regulator
KNP414_RS03710	COG2972	Histidine kinase
KNP414_RS03715	COG1879	ABC-type sugar transport system periplasmic component
KNP414_RS03720	COG2226	methyltransferase
KNP414_RS03725	COG0494	nUDIX hydrolase
KNP414_RS03735	COG1902	pentaerythritol trinitrate reductase activity
KNP414_RS03740	COG1653	transport
KNP414_RS03745	COG3275	phosphorelay sensor kinase activity
KNP414_RS03750	COG4753	response regulator
KNP414_RS03750	COG2207	Transcriptional regulator
KNP414_RS03760	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KNP414_RS03765	COG1070	Carbohydrate kinase
KNP414_RS03775	COG5577	PFAM Coat F domain
KNP414_RS03780	COG1063	alcohol dehydrogenase
KNP414_RS03790	COG5577	PFAM Coat F domain
KNP414_RS03800	COG5577	PFAM Coat F domain
KNP414_RS03805	COG1522	sequence-specific DNA binding
KNP414_RS03810	COG0402	S-adenosylhomocysteine deaminase activity
KNP414_RS03815	COG4603	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS03820	COG1079	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS03825	COG3845	ABC transporter
KNP414_RS03840	COG1309	transcriptional regulator
KNP414_RS03850	COG3540	Alkaline phosphatase
KNP414_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS03865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNP414_RS03870	COG1279	arginine transmembrane transporter activity
KNP414_RS03875	COG0243	molybdopterin cofactor binding
KNP414_RS03890	COG0531	amino acid
KNP414_RS03900	COG3665	Urea carboxylase-associated protein
KNP414_RS03905	COG0439	Biotin carboxylase
KNP414_RS03920	COG2223	nitrite transmembrane transporter activity
KNP414_RS03925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNP414_RS03930	COG0243	molybdopterin cofactor binding
KNP414_RS03940	COG1368	sulfuric ester hydrolase activity
KNP414_RS03955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KNP414_RS03960	COG4585	Histidine kinase
KNP414_RS03965	COG1027	Aspartate ammonia-lyase
KNP414_RS03970	COG1301	dicarboxylic acid transport
KNP414_RS03980	COG4191	Histidine kinase
KNP414_RS03985	COG0784	Response regulator, receiver
KNP414_RS03995	COG3866	Pectate lyase
KNP414_RS04000	COG4209	transmembrane transport
KNP414_RS04005	COG0395	ABC-type sugar transport system, permease component
KNP414_RS04010	COG1653	transport
KNP414_RS04015	COG0385	Bile acid
KNP414_RS04045	COG0697	spore germination
KNP414_RS04055	COG1840	ABC-type Fe3 transport system, periplasmic component
KNP414_RS04060	COG3842	ATPase activity
KNP414_RS04075	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KNP414_RS04085	COG1349	DNA-binding transcription factor activity
KNP414_RS04095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KNP414_RS04100	COG1360	Flagellar Motor Protein
KNP414_RS04190	COG4846	Membrane protein involved in cytochrome C biogenesis
KNP414_RS04200	COG1744	ABC transporter substrate-binding protein PnrA-like
KNP414_RS04205	COG3845	ABC transporter
KNP414_RS04210	COG4603	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS04215	COG1079	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS04225	COG2226	methyltransferase
KNP414_RS04235	COG2814	Major facilitator Superfamily
KNP414_RS04245	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KNP414_RS04260	COG3069	C4-dicarboxylate transmembrane transporter activity
KNP414_RS04265	COG0561	phosphatase activity
KNP414_RS04280	COG0737	Belongs to the 5'-nucleotidase family
KNP414_RS04285	COG0534	Mate efflux family protein
KNP414_RS04295	COG3384	dioxygenase
KNP414_RS04325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KNP414_RS04335	COG0726	polysaccharide deacetylase
KNP414_RS04345	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS04360	COG0367	asparagine synthase
KNP414_RS04375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KNP414_RS04385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KNP414_RS04390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KNP414_RS04405	COG1486	melibiose metabolic process
KNP414_RS04430	COG1132	(ABC) transporter
KNP414_RS04440	COG0730	response to heat
KNP414_RS04445	COG0346	lactoylglutathione lyase activity
KNP414_RS04465	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KNP414_RS04470	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KNP414_RS04485	COG0697	spore germination
KNP414_RS04500	COG0583	DNA-binding transcription factor activity
KNP414_RS04505	COG0586	Pfam SNARE associated Golgi protein
KNP414_RS04515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNP414_RS04535	COG2207	Transcriptional regulator
KNP414_RS04535	COG4753	response regulator
KNP414_RS04535	COG4753	response regulator
KNP414_RS04535	COG2207	Transcriptional regulator
KNP414_RS04540	COG5002	protein histidine kinase activity
KNP414_RS04545	COG4209	transmembrane transport
KNP414_RS04550	COG0395	ABC-type sugar transport system, permease component
KNP414_RS04555	COG1653	transport
KNP414_RS04570	COG0110	maltose O-acetyltransferase activity
KNP414_RS04575	COG1653	transport
KNP414_RS04580	COG0395	ABC-type sugar transport system, permease component
KNP414_RS04585	COG1175	transmembrane transport
KNP414_RS04630	COG0006	proline dipeptidase activity
KNP414_RS04640	COG0583	DNA-binding transcription factor activity
KNP414_RS04650	COG2200	EAL domain
KNP414_RS04655	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNP414_RS04660	COG0154	amidase activity
KNP414_RS04665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNP414_RS04670	COG0456	acetyltransferase
KNP414_RS04670	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KNP414_RS04680	COG1285	pathogenesis
KNP414_RS04705	COG0735	belongs to the Fur family
KNP414_RS04725	COG2104	thiamine diphosphate biosynthetic process
KNP414_RS04730	COG2022	thiamine diphosphate biosynthetic process
KNP414_RS04850	COG3852	Histidine kinase
KNP414_RS04865	COG2363	Small membrane protein
KNP414_RS04870	COG3377	Domain of unknown function (DUF1805)
KNP414_RS04880	COG0716	FMN binding
KNP414_RS04885	COG2186	Transcriptional regulator
KNP414_RS04910	COG0402	S-adenosylhomocysteine deaminase activity
KNP414_RS04925	COG0714	Associated with various cellular activities
KNP414_RS04940	COG1414	Transcriptional regulator
KNP414_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS04950	COG0179	Fumarylacetoacetate (FAA) hydrolase
KNP414_RS04960	COG2721	sulfolactate sulfo-lyase activity
KNP414_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS04975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KNP414_RS04980	COG0363	glucosamine-6-phosphate deaminase activity
KNP414_RS04985	COG1737	Transcriptional regulator
KNP414_RS04995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KNP414_RS05000	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KNP414_RS05020	COG0396	ATPase activity
KNP414_RS05025	COG0719	Fe-S assembly protein
KNP414_RS05030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNP414_RS05035	COG0822	iron-sulfur transferase activity
KNP414_RS05040	COG0719	Fe-S assembly protein
KNP414_RS05050	COG0662	Cupin 2, conserved barrel domain protein
KNP414_RS05065	COG0840	transmembrane signaling receptor activity
KNP414_RS05095	COG0840	transmembrane signaling receptor activity
KNP414_RS05100	COG3547	Transposase (IS116 IS110 IS902 family)
KNP414_RS05155	COG4221	oxidoreductase activity
KNP414_RS05160	COG1733	regulation of RNA biosynthetic process
KNP414_RS05170	COG2084	Dehydrogenase
KNP414_RS05175	COG3547	Transposase (IS116 IS110 IS902 family)
KNP414_RS05180	COG1027	Aspartate ammonia-lyase
KNP414_RS05190	COG0252	asparaginase activity
KNP414_RS05200	COG1846	Transcriptional regulator
KNP414_RS05210	COG0702	epimerase
KNP414_RS05215	COG3547	Transposase (IS116 IS110 IS902 family)
KNP414_RS05220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KNP414_RS05225	COG0583	DNA-binding transcription factor activity
KNP414_RS05255	COG2814	Major facilitator Superfamily
KNP414_RS05280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNP414_RS05315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KNP414_RS05320	COG0314	molybdopterin synthase activity
KNP414_RS05330	COG0737	Belongs to the 5'-nucleotidase family
KNP414_RS05335	COG0535	radical SAM domain protein
KNP414_RS05340	COG1253	flavin adenine dinucleotide binding
KNP414_RS05345	COG0628	permease
KNP414_RS05350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNP414_RS05355	COG1388	LysM domain
KNP414_RS05355	COG0791	NLP P60 protein
KNP414_RS05370	COG3546	catalase activity
KNP414_RS05455	COG0582	viral genome integration into host DNA
KNP414_RS05490	COG1802	Transcriptional regulator
KNP414_RS05490	COG4626	Terminase
KNP414_RS05585	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNP414_RS05585	COG3409	Peptidoglycan-binding domain 1 protein
KNP414_RS05595	COG3328	transposase activity
KNP414_RS05640	COG3546	catalase activity
KNP414_RS05670	COG0189	ligase activity
KNP414_RS05675	COG0189	ligase activity
KNP414_RS05695	COG0189	ligase activity
KNP414_RS05730	COG1349	DNA-binding transcription factor activity
KNP414_RS05745	COG4109	DRTGG domain
KNP414_RS05765	COG0587	DNA-directed DNA polymerase activity
KNP414_RS05770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KNP414_RS05780	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KNP414_RS05795	COG0824	Thioesterase
KNP414_RS05800	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KNP414_RS05810	COG0372	Belongs to the citrate synthase family
KNP414_RS05815	COG0538	isocitrate dehydrogenase activity
KNP414_RS05825	COG0039	L-malate dehydrogenase activity
KNP414_RS05840	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KNP414_RS05850	COG0385	Bile acid
KNP414_RS05855	COG5002	protein histidine kinase activity
KNP414_RS05860	COG0745	RESPONSE REGULATOR receiver
KNP414_RS05875	COG0840	transmembrane signaling receptor activity
KNP414_RS05880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KNP414_RS05885	COG0573	inorganic phosphate transmembrane transporter activity
KNP414_RS05890	COG0581	inorganic phosphate transmembrane transporter activity
KNP414_RS05895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KNP414_RS05900	COG0704	Plays a role in the regulation of phosphate uptake
KNP414_RS05910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNP414_RS05910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNP414_RS05915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KNP414_RS05920	COG1971	Probably functions as a manganese efflux pump
KNP414_RS05925	COG0237	dephospho-CoA kinase activity
KNP414_RS05940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KNP414_RS05965	COG0640	Transcriptional regulator
KNP414_RS05975	COG0596	Alpha beta hydrolase
KNP414_RS06005	COG0604	alcohol dehydrogenase
KNP414_RS06020	COG0454	-acetyltransferase
KNP414_RS06020	COG0456	acetyltransferase
KNP414_RS06025	COG2207	Transcriptional regulator
KNP414_RS06025	COG4753	response regulator
KNP414_RS06030	COG2972	Histidine kinase
KNP414_RS06040	COG1175	transmembrane transport
KNP414_RS06045	COG3833	ABC-type maltose transport systems, permease component
KNP414_RS06055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNP414_RS06055	COG0574	Belongs to the PEP-utilizing enzyme family
KNP414_RS06060	COG1695	Transcriptional regulator
KNP414_RS06075	COG1937	Protein conserved in bacteria
KNP414_RS06080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNP414_RS06085	COG0425	Belongs to the sulfur carrier protein TusA family
KNP414_RS06090	COG2210	Belongs to the sulfur carrier protein TusA family
KNP414_RS06095	COG0425	Belongs to the sulfur carrier protein TusA family
KNP414_RS06095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNP414_RS06100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNP414_RS06100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNP414_RS06130	COG0494	nUDIX hydrolase
KNP414_RS06140	COG0477	Major facilitator Superfamily
KNP414_RS06155	COG2085	NADP oxidoreductase coenzyme F420-dependent
KNP414_RS06165	COG0596	Alpha beta hydrolase
KNP414_RS06175	COG2378	regulation of single-species biofilm formation
KNP414_RS06180	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS06195	COG2085	NADP oxidoreductase coenzyme F420-dependent
KNP414_RS06200	COG1309	transcriptional regulator
KNP414_RS06205	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS06210	COG0300	oxidoreductase activity
KNP414_RS06215	COG1063	alcohol dehydrogenase
KNP414_RS06225	COG2226	methyltransferase
KNP414_RS06245	COG4585	Histidine kinase
KNP414_RS06250	COG2197	response regulator
KNP414_RS06275	COG1472	Belongs to the glycosyl hydrolase 3 family
KNP414_RS06305	COG2814	Major facilitator Superfamily
KNP414_RS06315	COG4753	response regulator
KNP414_RS06315	COG2207	Transcriptional regulator
KNP414_RS06330	COG1175	transmembrane transport
KNP414_RS06350	COG1017	nitric oxide dioxygenase activity
KNP414_RS06350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KNP414_RS06370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KNP414_RS06395	COG0243	molybdopterin cofactor binding
KNP414_RS06440	COG1151	hydroxylamine reductase activity
KNP414_RS06445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNP414_RS06455	COG2197	response regulator
KNP414_RS06460	COG4585	Histidine kinase
KNP414_RS06475	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KNP414_RS06480	COG1012	belongs to the aldehyde dehydrogenase family
KNP414_RS06480	COG1454	alcohol dehydrogenase
KNP414_RS06485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNP414_RS06495	COG0746	molybdenum cofactor guanylyltransferase activity
KNP414_RS06500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KNP414_RS06500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KNP414_RS06510	COG0791	NLP P60 protein
KNP414_RS06525	COG2986	histidine ammonia-lyase
KNP414_RS06530	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KNP414_RS06535	COG1228	amidohydrolase
KNP414_RS06545	COG0402	S-adenosylhomocysteine deaminase activity
KNP414_RS06550	COG0366	Alpha amylase catalytic
KNP414_RS06550	COG1874	Beta-galactosidase
KNP414_RS06560	COG0697	spore germination
KNP414_RS06565	COG0531	amino acid
KNP414_RS06585	COG3845	ABC transporter
KNP414_RS06595	COG1079	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS06610	COG1609	Transcriptional regulator
KNP414_RS06615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNP414_RS06650	COG5002	protein histidine kinase activity
KNP414_RS06655	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS06675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KNP414_RS06695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNP414_RS06705	COG2720	vancomycin resistance protein
KNP414_RS06720	COG0840	transmembrane signaling receptor activity
KNP414_RS06725	COG0523	cobalamin synthesis protein
KNP414_RS06730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KNP414_RS06735	COG0390	transport system, permease component
KNP414_RS06740	COG2318	DinB family
KNP414_RS06760	COG1069	ribulokinase activity
KNP414_RS06800	COG1846	Transcriptional regulator
KNP414_RS06845	COG0352	thiamine-phosphate diphosphorylase activity
KNP414_RS06850	COG0351	phosphomethylpyrimidine kinase
KNP414_RS06880	COG0242	peptide deformylase activity
KNP414_RS06885	COG1316	TRANSCRIPTIONal
KNP414_RS06895	COG0745	RESPONSE REGULATOR receiver
KNP414_RS06900	COG5002	protein histidine kinase activity
KNP414_RS06905	COG0800	Aldolase
KNP414_RS06920	COG0129	dihydroxy-acid dehydratase activity
KNP414_RS06935	COG1266	CAAX protease self-immunity
KNP414_RS07005	COG2207	Transcriptional regulator
KNP414_RS07005	COG0662	Cupin 2, conserved barrel domain protein
KNP414_RS07010	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KNP414_RS07015	COG1486	melibiose metabolic process
KNP414_RS07025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KNP414_RS07035	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
KNP414_RS07040	COG2169	Transcriptional regulator
KNP414_RS07040	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS07050	COG0628	permease
KNP414_RS07055	COG1733	regulation of RNA biosynthetic process
KNP414_RS07060	COG0316	Belongs to the HesB IscA family
KNP414_RS07065	COG4844	belongs to the
KNP414_RS07085	COG0116	Belongs to the methyltransferase superfamily
KNP414_RS07090	COG4122	O-methyltransferase activity
KNP414_RS07095	COG2318	DinB family
KNP414_RS07110	COG2843	Capsule synthesis protein
KNP414_RS07115	COG0179	Fumarylacetoacetate (FAA) hydrolase
KNP414_RS07130	COG5416	Lipopolysaccharide assembly protein A domain
KNP414_RS07135	COG1164	Oligoendopeptidase f
KNP414_RS07145	COG0861	Integral membrane protein TerC family
KNP414_RS07170	COG0659	secondary active sulfate transmembrane transporter activity
KNP414_RS07180	COG0577	efflux transmembrane transporter activity
KNP414_RS07185	COG1136	(ABC) transporter
KNP414_RS07190	COG2814	Major facilitator Superfamily
KNP414_RS07225	COG0431	NADPH-dependent FMN reductase
KNP414_RS07230	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KNP414_RS07250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KNP414_RS07275	COG0513	Belongs to the DEAD box helicase family
KNP414_RS07280	COG5578	integral membrane protein
KNP414_RS07285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KNP414_RS07290	COG1070	Carbohydrate kinase
KNP414_RS07305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KNP414_RS07310	COG0583	DNA-binding transcription factor activity
KNP414_RS07315	COG4533	DNA binding
KNP414_RS07320	COG2738	Putative neutral zinc metallopeptidase
KNP414_RS07325	COG0789	Transcriptional regulator
KNP414_RS07330	COG0004	ammonium transporteR
KNP414_RS07340	COG2176	DNA-directed DNA polymerase activity
KNP414_RS07350	COG2814	Major facilitator Superfamily
KNP414_RS07355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNP414_RS07360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KNP414_RS07365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNP414_RS07370	COG1763	Mo-molybdopterin cofactor biosynthetic process
KNP414_RS07375	COG1141	Ferredoxin
KNP414_RS07395	COG0167	dihydroorotate dehydrogenase activity
KNP414_RS07400	COG2357	RelA SpoT domain protein
KNP414_RS07405	COG1547	Domain of unknown function (DUF309)
KNP414_RS07410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNP414_RS07415	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KNP414_RS07415	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KNP414_RS07420	COG1187	pseudouridine synthase activity
KNP414_RS07425	COG0561	phosphatase activity
KNP414_RS07435	COG3237	CsbD-like
KNP414_RS07440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KNP414_RS07440	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KNP414_RS07445	COG0720	synthase
KNP414_RS07450	COG0602	queuosine metabolic process
KNP414_RS07455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KNP414_RS07465	COG2746	aminoglycoside 3-N-acetyltransferase activity
KNP414_RS07470	COG3706	GGDEF domain
KNP414_RS07475	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS07485	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS07500	COG3949	Membrane
KNP414_RS07505	COG0586	Pfam SNARE associated Golgi protein
KNP414_RS07515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNP414_RS07550	COG1316	TRANSCRIPTIONal
KNP414_RS07565	COG0018	arginyl-trna synthetase
KNP414_RS07580	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KNP414_RS07595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNP414_RS07600	COG0095	Lipoate-protein ligase
KNP414_RS07625	COG2182	Extracellular solute-binding protein
KNP414_RS07650	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KNP414_RS07655	COG2972	Histidine kinase
KNP414_RS07660	COG2169	Transcriptional regulator
KNP414_RS07675	COG4209	transmembrane transport
KNP414_RS07680	COG0395	ABC-type sugar transport system, permease component
KNP414_RS07695	COG2207	Transcriptional regulator
KNP414_RS07695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNP414_RS07725	COG2972	Histidine kinase
KNP414_RS07730	COG4753	response regulator
KNP414_RS07730	COG2207	Transcriptional regulator
KNP414_RS07735	COG1653	transport
KNP414_RS07740	COG3250	beta-galactosidase activity
KNP414_RS07745	COG4209	transmembrane transport
KNP414_RS07750	COG0395	ABC-type sugar transport system, permease component
KNP414_RS07765	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS07765	COG2169	Transcriptional regulator
KNP414_RS07770	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS07770	COG2207	Transcriptional regulator
KNP414_RS07780	COG2207	Transcriptional regulator
KNP414_RS07785	COG0667	Aldo Keto reductase
KNP414_RS07795	COG3250	beta-galactosidase activity
KNP414_RS07800	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS07835	COG2207	Transcriptional regulator
KNP414_RS07840	COG3275	phosphorelay sensor kinase activity
KNP414_RS07845	COG4209	transmembrane transport
KNP414_RS07850	COG0395	ABC-type sugar transport system, permease component
KNP414_RS07855	COG1653	transport
KNP414_RS07895	COG0697	spore germination
KNP414_RS07905	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KNP414_RS07915	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KNP414_RS07920	COG3292	Two component regulator propeller
KNP414_RS07920	COG0745	RESPONSE REGULATOR receiver
KNP414_RS07920	COG2205	protein histidine kinase activity
KNP414_RS07925	COG0673	inositol 2-dehydrogenase activity
KNP414_RS07930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KNP414_RS07935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNP414_RS07950	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS07950	COG4977	sequence-specific DNA binding
KNP414_RS07955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNP414_RS07970	COG4251	negative regulation of phosphorylation
KNP414_RS07970	COG5001	Diguanylate cyclase
KNP414_RS07970	COG2203	Gaf domain
KNP414_RS07970	COG3706	GGDEF domain
KNP414_RS08020	COG1653	transport
KNP414_RS08025	COG0395	ABC-type sugar transport system, permease component
KNP414_RS08030	COG4209	transmembrane transport
KNP414_RS08035	COG2207	Transcriptional regulator
KNP414_RS08070	COG2207	Transcriptional regulator
KNP414_RS08075	COG4209	transmembrane transport
KNP414_RS08080	COG0395	ABC-type sugar transport system, permease component
KNP414_RS08085	COG1653	transport
KNP414_RS08095	COG0697	spore germination
KNP414_RS08140	COG5002	protein histidine kinase activity
KNP414_RS08145	COG0745	RESPONSE REGULATOR receiver
KNP414_RS08155	COG2132	Multicopper oxidase
KNP414_RS08165	COG0644	oxidoreductase
KNP414_RS08175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNP414_RS08180	COG1929	Belongs to the glycerate kinase type-1 family
KNP414_RS08210	COG4753	response regulator
KNP414_RS08210	COG2207	Transcriptional regulator
KNP414_RS08215	COG0583	DNA-binding transcription factor activity
KNP414_RS08220	COG0583	DNA-binding transcription factor activity
KNP414_RS08235	COG4753	response regulator
KNP414_RS08235	COG2207	Transcriptional regulator
KNP414_RS08240	COG0583	DNA-binding transcription factor activity
KNP414_RS08245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KNP414_RS08260	COG2972	Histidine kinase
KNP414_RS08265	COG2207	Transcriptional regulator
KNP414_RS08270	COG1653	transport
KNP414_RS08275	COG4209	transmembrane transport
KNP414_RS08280	COG0395	ABC-type sugar transport system, permease component
KNP414_RS08290	COG1472	Belongs to the glycosyl hydrolase 3 family
KNP414_RS08305	COG1957	nucleoside hydrolase
KNP414_RS08310	COG3250	beta-galactosidase activity
KNP414_RS08325	COG0789	Transcriptional regulator
KNP414_RS08335	COG4221	oxidoreductase activity
KNP414_RS08340	COG2207	Transcriptional regulator
KNP414_RS08355	COG0346	lactoylglutathione lyase activity
KNP414_RS08385	COG2244	polysaccharide biosynthetic process
KNP414_RS08400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KNP414_RS08400	COG2070	2-Nitropropane dioxygenase
KNP414_RS08405	COG3321	synthase
KNP414_RS08405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNP414_RS08405	COG0300	oxidoreductase activity
KNP414_RS08405	COG4221	oxidoreductase activity
KNP414_RS08410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNP414_RS08410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KNP414_RS08410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNP414_RS08410	COG3321	synthase
KNP414_RS08410	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS08415	COG4221	oxidoreductase activity
KNP414_RS08415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNP414_RS08415	COG3321	synthase
KNP414_RS08415	COG3321	synthase
KNP414_RS08415	COG4221	oxidoreductase activity
KNP414_RS08415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNP414_RS08415	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS08415	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS08435	COG1609	Transcriptional regulator
KNP414_RS08440	COG4209	transmembrane transport
KNP414_RS08445	COG0395	ABC-type sugar transport system, permease component
KNP414_RS08455	COG1621	beta-fructofuranosidase activity
KNP414_RS08460	COG1621	beta-fructofuranosidase activity
KNP414_RS08475	COG5297	Belongs to the glycosyl hydrolase family 6
KNP414_RS08475	COG4733	cellulase activity
KNP414_RS08485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KNP414_RS08490	COG1063	alcohol dehydrogenase
KNP414_RS08520	COG0747	negative chemotaxis
KNP414_RS08530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNP414_RS08535	COG0444	Belongs to the ABC transporter superfamily
KNP414_RS08540	COG1124	(ABC) transporter
KNP414_RS08565	COG0583	DNA-binding transcription factor activity
KNP414_RS08580	COG0697	spore germination
KNP414_RS08595	COG2207	Transcriptional regulator
KNP414_RS08600	COG4209	transmembrane transport
KNP414_RS08605	COG0395	ABC-type sugar transport system, permease component
KNP414_RS08610	COG1653	transport
KNP414_RS08615	COG1378	Sugar-specific transcriptional regulator TrmB
KNP414_RS08645	COG1309	transcriptional regulator
KNP414_RS08650	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNP414_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS08660	COG0666	response to abiotic stimulus
KNP414_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS08685	COG1942	4-Oxalocrotonate Tautomerase
KNP414_RS08690	COG1349	DNA-binding transcription factor activity
KNP414_RS08695	COG3718	enzyme involved in inositol metabolism
KNP414_RS08700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNP414_RS08705	COG0191	fructose-bisphosphate aldolase activity
KNP414_RS08710	COG1349	DNA-binding transcription factor activity
KNP414_RS08725	COG1063	alcohol dehydrogenase
KNP414_RS08735	COG2972	Histidine kinase
KNP414_RS08740	COG2207	Transcriptional regulator
KNP414_RS08740	COG4753	response regulator
KNP414_RS08740	COG2207	Transcriptional regulator
KNP414_RS08740	COG4753	response regulator
KNP414_RS08755	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNP414_RS08770	COG0583	DNA-binding transcription factor activity
KNP414_RS08775	COG0384	phenazine biosynthesis protein PhzF
KNP414_RS08805	COG0504	CTP synthase activity
KNP414_RS08815	COG3328	transposase activity
KNP414_RS08825	COG1653	transport
KNP414_RS08835	COG2207	Transcriptional regulator
KNP414_RS08835	COG4753	response regulator
KNP414_RS08840	COG1621	beta-fructofuranosidase activity
KNP414_RS08845	COG1175	transmembrane transport
KNP414_RS08850	COG0395	ABC-type sugar transport system, permease component
KNP414_RS08855	COG1621	beta-fructofuranosidase activity
KNP414_RS08875	COG1309	transcriptional regulator
KNP414_RS08880	COG2076	Multidrug Resistance protein
KNP414_RS08885	COG2076	Multidrug Resistance protein
KNP414_RS08895	COG2814	Major facilitator Superfamily
KNP414_RS08910	COG4209	transmembrane transport
KNP414_RS08915	COG0395	ABC-type sugar transport system, permease component
KNP414_RS08920	COG1653	transport
KNP414_RS08925	COG2207	Transcriptional regulator
KNP414_RS08935	COG1309	transcriptional regulator
KNP414_RS08950	COG2755	lipolytic protein G-D-S-L family
KNP414_RS08955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KNP414_RS08960	COG2207	Transcriptional regulator
KNP414_RS08965	COG4209	transmembrane transport
KNP414_RS08970	COG0395	ABC-type sugar transport system, permease component
KNP414_RS08975	COG1653	transport
KNP414_RS08985	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KNP414_RS08990	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS08990	COG2207	Transcriptional regulator
KNP414_RS08995	COG3401	FG-GAP repeat protein
KNP414_RS09005	COG1687	branched-chain amino acid
KNP414_RS09015	COG1879	ABC-type sugar transport system periplasmic component
KNP414_RS09020	COG1129	ABC transporter
KNP414_RS09025	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS09030	COG1609	Transcriptional regulator
KNP414_RS09045	COG4209	transmembrane transport
KNP414_RS09050	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09060	COG1621	beta-fructofuranosidase activity
KNP414_RS09070	COG1335	isochorismatase
KNP414_RS09090	COG2814	Major facilitator Superfamily
KNP414_RS09095	COG0783	Belongs to the Dps family
KNP414_RS09105	COG0346	lactoylglutathione lyase activity
KNP414_RS09110	COG0400	carboxylic ester hydrolase activity
KNP414_RS09155	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KNP414_RS09160	COG1522	sequence-specific DNA binding
KNP414_RS09165	COG0477	Major facilitator Superfamily
KNP414_RS09170	COG0640	Transcriptional regulator
KNP414_RS09175	COG2814	Major facilitator Superfamily
KNP414_RS09180	COG4209	transmembrane transport
KNP414_RS09185	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09190	COG1653	transport
KNP414_RS09205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS09210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS09225	COG3401	FG-GAP repeat protein
KNP414_RS09235	COG1063	alcohol dehydrogenase
KNP414_RS09240	COG2211	Major facilitator Superfamily
KNP414_RS09245	COG0457	Tetratricopeptide repeat
KNP414_RS09250	COG0697	spore germination
KNP414_RS09265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KNP414_RS09275	COG3620	sequence-specific DNA binding
KNP414_RS09295	COG2207	Transcriptional regulator
KNP414_RS09300	COG1653	transport
KNP414_RS09305	COG4209	transmembrane transport
KNP414_RS09310	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09315	COG3250	beta-galactosidase activity
KNP414_RS09320	COG1802	Transcriptional regulator
KNP414_RS09325	COG1312	Catalyzes the dehydration of D-mannonate
KNP414_RS09330	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS09360	COG1175	transmembrane transport
KNP414_RS09365	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09370	COG2972	Histidine kinase
KNP414_RS09380	COG2207	Transcriptional regulator
KNP414_RS09380	COG4753	response regulator
KNP414_RS09380	COG2207	Transcriptional regulator
KNP414_RS09380	COG4753	response regulator
KNP414_RS09385	COG1063	alcohol dehydrogenase
KNP414_RS09395	COG1793	dna ligase
KNP414_RS09405	COG2910	NAD(P)H-binding
KNP414_RS09410	COG0109	protoheme IX farnesyltransferase activity
KNP414_RS09420	COG0179	Fumarylacetoacetate (FAA) hydrolase
KNP414_RS09430	COG0129	dihydroxy-acid dehydratase activity
KNP414_RS09435	COG0579	oxidoreductase
KNP414_RS09460	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNP414_RS09480	COG3250	beta-galactosidase activity
KNP414_RS09490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KNP414_RS09515	COG1175	transmembrane transport
KNP414_RS09520	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09535	COG2972	Histidine kinase
KNP414_RS09540	COG4753	response regulator
KNP414_RS09540	COG2207	Transcriptional regulator
KNP414_RS09550	COG0662	Cupin 2, conserved barrel domain protein
KNP414_RS09555	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
KNP414_RS09575	COG0745	RESPONSE REGULATOR receiver
KNP414_RS09580	COG0366	Alpha amylase catalytic
KNP414_RS09580	COG1874	Beta-galactosidase
KNP414_RS09585	COG4251	negative regulation of phosphorylation
KNP414_RS09585	COG3706	GGDEF domain
KNP414_RS09585	COG5001	Diguanylate cyclase
KNP414_RS09585	COG2203	Gaf domain
KNP414_RS09600	COG1653	transport
KNP414_RS09605	COG0840	transmembrane signaling receptor activity
KNP414_RS09610	COG2972	Histidine kinase
KNP414_RS09615	COG4565	transcriptional regulatory protein
KNP414_RS09625	COG0366	Alpha amylase catalytic
KNP414_RS09635	COG1175	transmembrane transport
KNP414_RS09640	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09660	COG2972	Histidine kinase
KNP414_RS09665	COG2201	protein-glutamate methylesterase activity
KNP414_RS09670	COG1175	transmembrane transport
KNP414_RS09675	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09705	COG0697	spore germination
KNP414_RS09710	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KNP414_RS09715	COG2318	DinB family
KNP414_RS09745	COG2972	Histidine kinase
KNP414_RS09750	COG2207	Transcriptional regulator
KNP414_RS09750	COG4753	response regulator
KNP414_RS09770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KNP414_RS09775	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KNP414_RS09780	COG1175	transmembrane transport
KNP414_RS09785	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09795	COG3118	belongs to the thioredoxin family
KNP414_RS09820	COG0523	cobalamin synthesis protein
KNP414_RS09830	COG0154	amidase activity
KNP414_RS09835	COG5001	Diguanylate cyclase
KNP414_RS09835	COG3300	MHYT domain
KNP414_RS09850	COG4209	transmembrane transport
KNP414_RS09855	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09865	COG1874	Beta-galactosidase
KNP414_RS09870	COG1846	Transcriptional regulator
KNP414_RS09880	COG2259	Doxx family
KNP414_RS09885	COG2972	Histidine kinase
KNP414_RS09890	COG4753	response regulator
KNP414_RS09890	COG2207	Transcriptional regulator
KNP414_RS09905	COG4209	transmembrane transport
KNP414_RS09910	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09920	COG2972	Histidine kinase
KNP414_RS09960	COG0708	Exodeoxyribonuclease III
KNP414_RS09970	COG4209	transmembrane transport
KNP414_RS09975	COG0395	ABC-type sugar transport system, permease component
KNP414_RS09980	COG2972	Histidine kinase
KNP414_RS09985	COG2207	Transcriptional regulator
KNP414_RS09985	COG4753	response regulator
KNP414_RS10010	COG2205	protein histidine kinase activity
KNP414_RS10030	COG1510	regulation of RNA biosynthetic process
KNP414_RS10035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KNP414_RS10055	COG3250	beta-galactosidase activity
KNP414_RS10065	COG2972	Histidine kinase
KNP414_RS10070	COG2207	Transcriptional regulator
KNP414_RS10070	COG4753	response regulator
KNP414_RS10075	COG4753	response regulator
KNP414_RS10075	COG2207	Transcriptional regulator
KNP414_RS10080	COG4209	transmembrane transport
KNP414_RS10085	COG0395	ABC-type sugar transport system, permease component
KNP414_RS10115	COG0395	ABC-type sugar transport system, permease component
KNP414_RS10155	COG2207	Transcriptional regulator
KNP414_RS10155	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS10165	COG1175	transmembrane transport
KNP414_RS10170	COG0395	ABC-type sugar transport system, permease component
KNP414_RS10180	COG2972	Histidine kinase
KNP414_RS10185	COG2207	Transcriptional regulator
KNP414_RS10185	COG4753	response regulator
KNP414_RS10195	COG1175	transmembrane transport
KNP414_RS10200	COG0395	ABC-type sugar transport system, permease component
KNP414_RS10205	COG3250	beta-galactosidase activity
KNP414_RS10215	COG4585	Histidine kinase
KNP414_RS10220	COG2197	response regulator
KNP414_RS10235	COG0583	DNA-binding transcription factor activity
KNP414_RS10260	COG1278	Cold shock
KNP414_RS10275	COG4977	sequence-specific DNA binding
KNP414_RS10285	COG1653	transport
KNP414_RS10290	COG1175	transmembrane transport
KNP414_RS10295	COG0395	ABC-type sugar transport system, permease component
KNP414_RS10345	COG1280	lysine exporter protein (LysE YggA)
KNP414_RS10355	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KNP414_RS10365	COG3622	Belongs to the hyi family
KNP414_RS10370	COG0488	(ABC) transporter
KNP414_RS10380	COG0697	spore germination
KNP414_RS10385	COG0789	Transcriptional regulator
KNP414_RS10390	COG0534	Mate efflux family protein
KNP414_RS10405	COG0667	Aldo Keto reductase
KNP414_RS10415	COG2755	lipolytic protein G-D-S-L family
KNP414_RS10420	COG2197	response regulator
KNP414_RS10425	COG2124	cytochrome p450
KNP414_RS10435	COG0745	RESPONSE REGULATOR receiver
KNP414_RS10440	COG2205	protein histidine kinase activity
KNP414_RS10455	COG1968	undecaprenyl-diphosphatase activity
KNP414_RS10480	COG0640	Transcriptional regulator
KNP414_RS10490	COG1309	transcriptional regulator
KNP414_RS10510	COG3507	Belongs to the glycosyl hydrolase 43 family
KNP414_RS10520	COG2318	DinB family
KNP414_RS10570	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS10595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KNP414_RS10610	COG1164	Oligoendopeptidase f
KNP414_RS10620	COG0318	PFAM AMP-dependent synthetase and ligase
KNP414_RS10630	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS10660	COG4565	transcriptional regulatory protein
KNP414_RS10665	COG3290	protein histidine kinase activity
KNP414_RS10670	COG1234	tRNA 3'-trailer cleavage
KNP414_RS10680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNP414_RS10685	COG0697	spore germination
KNP414_RS10700	COG2207	Transcriptional regulator
KNP414_RS10705	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS10730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KNP414_RS10760	COG2132	Multicopper oxidase
KNP414_RS10785	COG2367	Beta-lactamase
KNP414_RS10805	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS10825	COG0789	Transcriptional regulator
KNP414_RS10830	COG4221	oxidoreductase activity
KNP414_RS10835	COG0789	Transcriptional regulator
KNP414_RS10840	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS10895	COG2404	hydrolase activity, acting on ester bonds
KNP414_RS10905	COG2814	Major facilitator Superfamily
KNP414_RS10910	COG4565	transcriptional regulatory protein
KNP414_RS10915	COG3290	protein histidine kinase activity
KNP414_RS10925	COG2851	Citrate transporter
KNP414_RS10930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KNP414_RS10935	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KNP414_RS10940	COG0488	(ABC) transporter
KNP414_RS10965	COG2972	Histidine kinase
KNP414_RS10970	COG2207	Transcriptional regulator
KNP414_RS10970	COG4753	response regulator
KNP414_RS10980	COG1175	transmembrane transport
KNP414_RS10985	COG0395	ABC-type sugar transport system, permease component
KNP414_RS11000	COG5001	Diguanylate cyclase
KNP414_RS11000	COG3300	MHYT domain
KNP414_RS11005	COG0028	Belongs to the TPP enzyme family
KNP414_RS11020	COG0028	Belongs to the TPP enzyme family
KNP414_RS11025	COG5002	protein histidine kinase activity
KNP414_RS11030	COG1116	anion transmembrane transporter activity
KNP414_RS11040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNP414_RS11045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KNP414_RS11050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KNP414_RS11070	COG0167	dihydroorotate dehydrogenase activity
KNP414_RS11085	COG3835	regulator
KNP414_RS11090	COG1012	belongs to the aldehyde dehydrogenase family
KNP414_RS11095	COG0840	transmembrane signaling receptor activity
KNP414_RS11100	COG1695	Transcriptional regulator
KNP414_RS11130	COG3507	Belongs to the glycosyl hydrolase 43 family
KNP414_RS11140	COG2226	methyltransferase
KNP414_RS11150	COG4209	transmembrane transport
KNP414_RS11155	COG0395	ABC-type sugar transport system, permease component
KNP414_RS11165	COG4753	response regulator
KNP414_RS11165	COG4753	response regulator
KNP414_RS11165	COG2207	Transcriptional regulator
KNP414_RS11165	COG2207	Transcriptional regulator
KNP414_RS11170	COG2972	Histidine kinase
KNP414_RS11175	COG0583	DNA-binding transcription factor activity
KNP414_RS11180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KNP414_RS11215	COG1131	(ABC) transporter
KNP414_RS11225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNP414_RS11245	COG1741	Belongs to the pirin family
KNP414_RS11255	COG1794	racemase activity, acting on amino acids and derivatives
KNP414_RS11260	COG0697	spore germination
KNP414_RS11265	COG0531	amino acid
KNP414_RS11285	COG0840	transmembrane signaling receptor activity
KNP414_RS11295	COG2017	converts alpha-aldose to the beta-anomer
KNP414_RS11315	COG0840	transmembrane signaling receptor activity
KNP414_RS11330	COG0740	serine-type endopeptidase activity
KNP414_RS11380	COG2723	6-phospho-beta-galactosidase activity
KNP414_RS11385	COG1609	Transcriptional regulator
KNP414_RS11410	COG1742	UPF0060 membrane protein
KNP414_RS11425	COG4213	ABC transporter substrate-binding protein
KNP414_RS11430	COG0840	transmembrane signaling receptor activity
KNP414_RS11435	COG5001	Diguanylate cyclase
KNP414_RS11435	COG3300	MHYT domain
KNP414_RS11440	COG1609	Transcriptional regulator
KNP414_RS11445	COG0673	inositol 2-dehydrogenase activity
KNP414_RS11450	COG2201	protein-glutamate methylesterase activity
KNP414_RS11455	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KNP414_RS11470	COG1132	(ABC) transporter
KNP414_RS11475	COG1132	(ABC) transporter
KNP414_RS11480	COG0124	histidyl-tRNA synthetase
KNP414_RS11485	COG1368	sulfuric ester hydrolase activity
KNP414_RS11495	COG0745	RESPONSE REGULATOR receiver
KNP414_RS11500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNP414_RS11510	COG0105	UTP biosynthetic process
KNP414_RS11525	COG2309	aminopeptidase activity
KNP414_RS11530	COG2169	Transcriptional regulator
KNP414_RS11535	COG0673	inositol 2-dehydrogenase activity
KNP414_RS11545	COG0583	DNA-binding transcription factor activity
KNP414_RS11550	COG2610	gluconate transmembrane transporter activity
KNP414_RS11555	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS11560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KNP414_RS11565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KNP414_RS11575	COG2124	cytochrome p450
KNP414_RS11580	COG2252	PERMEase
KNP414_RS11585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNP414_RS11590	COG2207	Transcriptional regulator
KNP414_RS11610	COG2814	Major facilitator Superfamily
KNP414_RS11620	COG3639	organic phosphonate transmembrane transporter activity
KNP414_RS11625	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KNP414_RS11630	COG0709	Synthesizes selenophosphate from selenide and ATP
KNP414_RS11635	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KNP414_RS11640	COG1733	regulation of RNA biosynthetic process
KNP414_RS11645	COG1012	belongs to the aldehyde dehydrogenase family
KNP414_RS11655	COG4876	unkown
KNP414_RS11660	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS11670	COG1136	(ABC) transporter
KNP414_RS11675	COG0577	efflux transmembrane transporter activity
KNP414_RS11675	COG1136	(ABC) transporter
KNP414_RS11690	COG1733	regulation of RNA biosynthetic process
KNP414_RS11700	COG4120	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS11705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KNP414_RS11705	COG1116	anion transmembrane transporter activity
KNP414_RS11730	COG0454	-acetyltransferase
KNP414_RS11750	COG1077	Cell shape determining protein MreB Mrl
KNP414_RS11765	COG2205	protein histidine kinase activity
KNP414_RS11785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KNP414_RS11810	COG1121	(ABC) transporter
KNP414_RS11815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KNP414_RS11820	COG0785	Cytochrome C biogenesis protein
KNP414_RS11825	COG1533	DNA photolyase activity
KNP414_RS11830	COG1321	iron dependent repressor
KNP414_RS11835	COG1752	Esterase of the alpha-beta hydrolase superfamily
KNP414_RS11845	COG3872	metal-dependent enzyme
KNP414_RS11855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KNP414_RS11860	COG0006	proline dipeptidase activity
KNP414_RS11865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KNP414_RS11875	COG4109	DRTGG domain
KNP414_RS11910	COG2707	UPF0756 membrane protein
KNP414_RS11915	COG2045	Belongs to the ComB family
KNP414_RS11920	COG1809	phosphosulfolactate synthase activity
KNP414_RS11930	COG3854	ATPases associated with a variety of cellular activities
KNP414_RS11970	COG0511	ligase activity, forming carbon-carbon bonds
KNP414_RS11975	COG0439	Biotin carboxylase
KNP414_RS11985	COG1302	Protein conserved in bacteria
KNP414_RS12000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KNP414_RS12005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KNP414_RS12010	COG1570	exodeoxyribonuclease VII activity
KNP414_RS12015	COG1722	exodeoxyribonuclease VII activity
KNP414_RS12025	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KNP414_RS12030	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KNP414_RS12040	COG1438	arginine binding
KNP414_RS12045	COG0497	DNA recombination
KNP414_RS12050	COG0750	zinc metalloprotease
KNP414_RS12055	COG0745	RESPONSE REGULATOR receiver
KNP414_RS12075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KNP414_RS12085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KNP414_RS12090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KNP414_RS12095	COG0022	dehydrogenase e1 component
KNP414_RS12100	COG0508	dehydrogenase complex catalyzes the overall conversion of
KNP414_RS12105	COG2195	Cleaves the N-terminal amino acid of tripeptides
KNP414_RS12120	COG1379	DNA repair
KNP414_RS12125	COG1300	Membrane
KNP414_RS12130	COG0735	belongs to the Fur family
KNP414_RS12135	COG0686	Belongs to the AlaDH PNT family
KNP414_RS12145	COG4974	Belongs to the 'phage' integrase family
KNP414_RS12175	COG1686	Belongs to the peptidase S11 family
KNP414_RS12180	COG1366	Belongs to the anti-sigma-factor antagonist family
KNP414_RS12185	COG2172	sigma factor antagonist activity
KNP414_RS12195	COG2155	Conserved Protein
KNP414_RS12210	COG0697	spore germination
KNP414_RS12215	COG0019	diaminopimelate decarboxylase activity
KNP414_RS12220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNP414_RS12225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KNP414_RS12225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KNP414_RS12235	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KNP414_RS12235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KNP414_RS12240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KNP414_RS12245	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KNP414_RS12250	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KNP414_RS12260	COG3874	Sporulation protein YtfJ
KNP414_RS12270	COG2135	peptidase activity
KNP414_RS12275	COG1686	Belongs to the peptidase S11 family
KNP414_RS12280	COG2715	membrane protein required for spore maturation
KNP414_RS12285	COG0700	Nucleoside recognition
KNP414_RS12295	COG1187	pseudouridine synthase activity
KNP414_RS12300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNP414_RS12305	COG1333	cytochrome c biogenesis protein
KNP414_RS12310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KNP414_RS12315	COG0745	RESPONSE REGULATOR receiver
KNP414_RS12320	COG5002	protein histidine kinase activity
KNP414_RS12325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KNP414_RS12330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNP414_RS12340	COG1266	CAAX protease self-immunity
KNP414_RS12350	COG0726	polysaccharide deacetylase
KNP414_RS12360	COG4862	establishment of competence for transformation
KNP414_RS12365	COG0358	DNA primase activity
KNP414_RS12370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KNP414_RS12375	COG2339	peptidase activity
KNP414_RS12380	COG2959	enzyme of heme biosynthesis
KNP414_RS12400	COG0204	Acyl-transferase
KNP414_RS12400	COG0318	PFAM AMP-dependent synthetase and ligase
KNP414_RS12405	COG0539	negative regulation of cytoplasmic translation
KNP414_RS12410	COG1304	FMN binding
KNP414_RS12430	COG1160	GTP binding
KNP414_RS12435	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KNP414_RS12455	COG0633	Ferredoxin
KNP414_RS12475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KNP414_RS12480	COG0776	regulation of translation
KNP414_RS12515	COG0163	prenyltransferase activity
KNP414_RS12520	COG0142	geranyltranstransferase activity
KNP414_RS12525	COG0105	UTP biosynthetic process
KNP414_RS12530	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KNP414_RS12535	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KNP414_RS12540	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KNP414_RS12555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KNP414_RS12560	COG0134	indole-3-glycerol-phosphate synthase activity
KNP414_RS12565	COG0135	phosphoribosylanthranilate isomerase activity
KNP414_RS12570	COG0133	tryptophan synthase activity
KNP414_RS12575	COG0159	tryptophan synthase activity
KNP414_RS12580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KNP414_RS12585	COG0287	Prephenate dehydrogenase
KNP414_RS12610	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KNP414_RS12615	COG5582	Belongs to the UPF0302 family
KNP414_RS12625	COG0723	plastoquinol--plastocyanin reductase activity
KNP414_RS12650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNP414_RS12655	COG1694	Mazg nucleotide pyrophosphohydrolase
KNP414_RS12665	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KNP414_RS12670	COG1803	Methylglyoxal synthase
KNP414_RS12680	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS12700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KNP414_RS12705	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KNP414_RS12710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KNP414_RS12720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KNP414_RS12720	COG1199	ATP-dependent helicase activity
KNP414_RS12725	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KNP414_RS12730	COG0306	phosphate transporter
KNP414_RS12735	COG1392	Phosphate transport regulator
KNP414_RS12740	COG0402	S-adenosylhomocysteine deaminase activity
KNP414_RS12755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KNP414_RS12760	COG0860	N-Acetylmuramoyl-L-alanine amidase
KNP414_RS12775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KNP414_RS12790	COG1132	(ABC) transporter
KNP414_RS12795	COG1132	(ABC) transporter
KNP414_RS12800	COG0739	heme binding
KNP414_RS12800	COG1196	nuclear chromosome segregation
KNP414_RS12800	COG0741	lytic transglycosylase activity
KNP414_RS12810	COG1131	(ABC) transporter
KNP414_RS12825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNP414_RS12830	COG1846	Transcriptional regulator
KNP414_RS12835	COG0564	pseudouridine synthase activity
KNP414_RS12840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KNP414_RS12840	COG0116	Belongs to the methyltransferase superfamily
KNP414_RS12850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KNP414_RS12855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KNP414_RS12860	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KNP414_RS12865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KNP414_RS12870	COG0297	glycogen (starch) synthase activity
KNP414_RS12875	COG5002	protein histidine kinase activity
KNP414_RS12885	COG0428	transporter
KNP414_RS12890	COG0392	lysyltransferase activity
KNP414_RS12890	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNP414_RS12895	COG2203	Gaf domain
KNP414_RS12895	COG5001	Diguanylate cyclase
KNP414_RS12895	COG4251	negative regulation of phosphorylation
KNP414_RS12895	COG3706	GGDEF domain
KNP414_RS12900	COG0024	Methionine aminopeptidase
KNP414_RS12935	COG1547	Domain of unknown function (DUF309)
KNP414_RS12945	COG3850	Histidine kinase
KNP414_RS12945	COG5002	protein histidine kinase activity
KNP414_RS12950	COG0288	reversible hydration of carbon dioxide
KNP414_RS12955	COG4918	Iron-sulphur cluster biosynthesis
KNP414_RS12960	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KNP414_RS12965	COG0531	amino acid
KNP414_RS12970	COG0697	spore germination
KNP414_RS12985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KNP414_RS12990	COG1116	anion transmembrane transporter activity
KNP414_RS12995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNP414_RS13025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KNP414_RS13035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KNP414_RS13045	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KNP414_RS13050	COG1923	regulation of RNA biosynthetic process
KNP414_RS13055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNP414_RS13060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNP414_RS13080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KNP414_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS13095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KNP414_RS13100	COG0464	growth
KNP414_RS13105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KNP414_RS13110	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KNP414_RS13115	COG0789	Transcriptional regulator
KNP414_RS13120	COG0174	glutamine synthetase
KNP414_RS13125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KNP414_RS13130	COG0791	NLP P60 protein
KNP414_RS13130	COG1388	LysM domain
KNP414_RS13135	COG4224	UPF0291 protein
KNP414_RS13140	COG0667	Aldo Keto reductase
KNP414_RS13150	COG1011	Hydrolase
KNP414_RS13155	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KNP414_RS13160	COG1410	methionine synthase
KNP414_RS13160	COG0646	methionine synthase
KNP414_RS13165	COG1234	tRNA 3'-trailer cleavage
KNP414_RS13180	COG1346	cytolysis
KNP414_RS13195	COG1988	membrane-bound metal-dependent
KNP414_RS13210	COG1216	Glycosyl transferase, family 2
KNP414_RS13225	COG1562	ergosterol biosynthetic process
KNP414_RS13240	COG1205	dead DEAH box helicase
KNP414_RS13240	COG1111	helicase
KNP414_RS13245	COG3359	exonuclease
KNP414_RS13250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KNP414_RS13255	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KNP414_RS13265	COG1119	ATPase activity
KNP414_RS13270	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KNP414_RS13275	COG2226	methyltransferase
KNP414_RS13345	COG1363	Peptidase, m42
KNP414_RS13350	COG0488	(ABC) transporter
KNP414_RS13355	COG0488	(ABC) transporter
KNP414_RS13375	COG5002	protein histidine kinase activity
KNP414_RS13380	COG2197	response regulator
KNP414_RS13390	COG2860	membrane
KNP414_RS13420	COG1733	regulation of RNA biosynthetic process
KNP414_RS13440	COG4682	membrane
KNP414_RS13455	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS13455	COG2382	esterase
KNP414_RS13460	COG0515	serine threonine protein kinase
KNP414_RS13460	COG2815	serine threonine protein kinase
KNP414_RS13465	COG1090	epimerase
KNP414_RS13480	COG2207	Transcriptional regulator
KNP414_RS13480	COG1609	Transcriptional regulator
KNP414_RS13490	COG0667	Aldo Keto reductase
KNP414_RS13515	COG1733	regulation of RNA biosynthetic process
KNP414_RS13525	COG2226	methyltransferase
KNP414_RS13530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KNP414_RS13530	COG3153	acetyltransferase
KNP414_RS13535	COG0456	acetyltransferase
KNP414_RS13545	COG2032	superoxide dismutase activity
KNP414_RS13550	COG0583	DNA-binding transcription factor activity
KNP414_RS13555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KNP414_RS13575	COG0386	Belongs to the glutathione peroxidase family
KNP414_RS13585	COG1606	tRNA processing
KNP414_RS13590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNP414_RS13595	COG1136	(ABC) transporter
KNP414_RS13625	COG5002	protein histidine kinase activity
KNP414_RS13635	COG3973	AAA domain
KNP414_RS13730	COG0739	heme binding
KNP414_RS13735	COG2814	Major facilitator Superfamily
KNP414_RS13750	COG1272	protein, Hemolysin III
KNP414_RS13765	COG0523	cobalamin synthesis protein
KNP414_RS13770	COG0735	belongs to the Fur family
KNP414_RS13775	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KNP414_RS13780	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KNP414_RS13785	COG4208	sulfate ABC transporter
KNP414_RS13790	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KNP414_RS13795	COG1073	alpha beta
KNP414_RS13800	COG5583	Uncharacterized small protein (DUF2292)
KNP414_RS13805	COG0431	NADPH-dependent FMN reductase
KNP414_RS13810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KNP414_RS13815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS13820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNP414_RS13825	COG1116	anion transmembrane transporter activity
KNP414_RS13830	COG0196	riboflavin kinase activity
KNP414_RS13835	COG1116	anion transmembrane transporter activity
KNP414_RS13840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNP414_RS13850	COG0667	Aldo Keto reductase
KNP414_RS13855	COG2814	Major facilitator Superfamily
KNP414_RS13860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNP414_RS13865	COG0765	amino acid transport
KNP414_RS13870	COG1126	abc transporter atp-binding protein
KNP414_RS13890	COG0492	ferredoxin-NADP+ reductase activity
KNP414_RS13905	COG2268	Band 7 protein
KNP414_RS13910	COG0534	Mate efflux family protein
KNP414_RS13915	COG0572	uridine kinase
KNP414_RS13920	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS13930	COG0366	Alpha amylase catalytic
KNP414_RS13935	COG1979	alcohol dehydrogenase
KNP414_RS13940	COG2814	Major facilitator Superfamily
KNP414_RS13950	COG0537	adenosine 5'-monophosphoramidase activity
KNP414_RS14020	COG2186	Transcriptional regulator
KNP414_RS14030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KNP414_RS14035	COG3958	Transketolase
KNP414_RS14040	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS14065	COG1120	ATPase activity
KNP414_RS14070	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS14075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS14085	COG2364	Membrane
KNP414_RS14090	COG2153	protein acetylation
KNP414_RS14095	COG1846	Transcriptional regulator
KNP414_RS14110	COG0640	Transcriptional regulator
KNP414_RS14120	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
KNP414_RS14140	COG1309	transcriptional regulator
KNP414_RS14145	COG1064	alcohol dehydrogenase
KNP414_RS14175	COG2207	Transcriptional regulator
KNP414_RS14175	COG1609	Transcriptional regulator
KNP414_RS14180	COG3250	beta-galactosidase activity
KNP414_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS14200	COG4948	Mandelate Racemase Muconate Lactonizing
KNP414_RS14230	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KNP414_RS14240	COG0778	Nitroreductase
KNP414_RS14245	COG1846	Transcriptional regulator
KNP414_RS14255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KNP414_RS14295	COG1053	succinate dehydrogenase
KNP414_RS14300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNP414_RS14310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNP414_RS14340	COG2890	protein-(glutamine-N5) methyltransferase activity
KNP414_RS14345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNP414_RS14370	COG4912	Dna alkylation repair
KNP414_RS14385	COG5002	protein histidine kinase activity
KNP414_RS14395	COG1733	regulation of RNA biosynthetic process
KNP414_RS14400	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KNP414_RS14435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNP414_RS14465	COG2508	Transcriptional regulator
KNP414_RS14470	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KNP414_RS14480	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KNP414_RS14485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KNP414_RS14490	COG2080	2 iron, 2 sulfur cluster binding
KNP414_RS14500	COG2201	protein-glutamate methylesterase activity
KNP414_RS14520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNP414_RS14530	COG0655	NAD(P)H dehydrogenase (quinone) activity
KNP414_RS14535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KNP414_RS14540	COG0402	S-adenosylhomocysteine deaminase activity
KNP414_RS14545	COG3648	Uricase
KNP414_RS14545	COG3195	allantoin biosynthetic process
KNP414_RS14555	COG2351	hydroxyisourate hydrolase activity
KNP414_RS14560	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KNP414_RS14565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KNP414_RS14570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KNP414_RS14575	COG0405	Gamma-glutamyltransferase
KNP414_RS14580	COG2059	Chromate
KNP414_RS14590	COG1695	Transcriptional regulator
KNP414_RS14605	COG0674	pyruvate-flavodoxin oxidoreductase activity
KNP414_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS14660	COG1956	GAF domain-containing protein
KNP414_RS14665	COG1307	EDD domain protein, DegV family
KNP414_RS14705	COG2949	membrane
KNP414_RS14715	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS14730	COG0477	Major facilitator Superfamily
KNP414_RS14745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KNP414_RS14755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNP414_RS14760	COG0686	Belongs to the AlaDH PNT family
KNP414_RS14765	COG2508	Transcriptional regulator
KNP414_RS14765	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KNP414_RS14770	COG1113	amino acid transport
KNP414_RS14800	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KNP414_RS14805	COG2733	membrane
KNP414_RS14835	COG3250	beta-galactosidase activity
KNP414_RS14870	COG1476	TRANSCRIPTIONal
KNP414_RS14900	COG0662	Cupin 2, conserved barrel domain protein
KNP414_RS14900	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KNP414_RS14925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KNP414_RS14990	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS14995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNP414_RS15005	COG0596	Alpha beta hydrolase
KNP414_RS15025	COG3481	metal-dependent phosphohydrolase, HD sub domain
KNP414_RS15040	COG2723	6-phospho-beta-galactosidase activity
KNP414_RS15045	COG0217	transcriptional regulatory protein
KNP414_RS15070	COG1309	transcriptional regulator
KNP414_RS15085	COG0653	protein targeting
KNP414_RS15110	COG1902	pentaerythritol trinitrate reductase activity
KNP414_RS15115	COG1309	transcriptional regulator
KNP414_RS15120	COG2818	Glycosylase
KNP414_RS15140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KNP414_RS15155	COG1361	Conserved repeat domain
KNP414_RS15165	COG3328	transposase activity
KNP414_RS15170	COG0656	L-ascorbic acid biosynthetic process
KNP414_RS15185	COG1733	regulation of RNA biosynthetic process
KNP414_RS15190	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNP414_RS15195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KNP414_RS15195	COG0456	acetyltransferase
KNP414_RS15200	COG0667	Aldo Keto reductase
KNP414_RS15205	COG0789	Transcriptional regulator
KNP414_RS15240	COG0640	Transcriptional regulator
KNP414_RS15245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KNP414_RS15250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KNP414_RS15255	COG0346	lactoylglutathione lyase activity
KNP414_RS15265	COG2072	flavoprotein involved in K transport
KNP414_RS15270	COG0346	lactoylglutathione lyase activity
KNP414_RS15280	COG0577	efflux transmembrane transporter activity
KNP414_RS15285	COG1136	(ABC) transporter
KNP414_RS15290	COG2205	protein histidine kinase activity
KNP414_RS15295	COG0745	RESPONSE REGULATOR receiver
KNP414_RS15300	COG2207	Transcriptional regulator
KNP414_RS15325	COG2207	Transcriptional regulator
KNP414_RS15330	COG1653	transport
KNP414_RS15340	COG0789	Transcriptional regulator
KNP414_RS15340	COG4978	Transcriptional regulator
KNP414_RS15345	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS15350	COG1349	DNA-binding transcription factor activity
KNP414_RS15365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KNP414_RS15365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KNP414_RS15365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KNP414_RS15375	COG2755	lipolytic protein G-D-S-L family
KNP414_RS15380	COG1012	belongs to the aldehyde dehydrogenase family
KNP414_RS15385	COG1388	LysM domain
KNP414_RS15385	COG1705	Flagellar rod assembly protein muramidase FlgJ
KNP414_RS15390	COG1653	transport
KNP414_RS15410	COG2207	Transcriptional regulator
KNP414_RS15410	COG4753	response regulator
KNP414_RS15415	COG2972	Histidine kinase
KNP414_RS15420	COG1879	ABC-type sugar transport system periplasmic component
KNP414_RS15430	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS15435	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS15470	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS15470	COG4977	sequence-specific DNA binding
KNP414_RS15480	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KNP414_RS15535	COG2011	ABC-type metal ion transport system permease component
KNP414_RS15550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNP414_RS15560	COG1309	transcriptional regulator
KNP414_RS15565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KNP414_RS15565	COG2124	cytochrome p450
KNP414_RS15585	COG0673	inositol 2-dehydrogenase activity
KNP414_RS15590	COG0667	Aldo Keto reductase
KNP414_RS15610	COG0681	Belongs to the peptidase S26 family
KNP414_RS15620	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS15630	COG2719	SpoVR family
KNP414_RS15635	COG2718	Belongs to the UPF0229 family
KNP414_RS15645	COG2502	aspartate--ammonia ligase
KNP414_RS15650	COG5002	protein histidine kinase activity
KNP414_RS15655	COG4753	response regulator
KNP414_RS15655	COG2207	Transcriptional regulator
KNP414_RS15660	COG2972	Histidine kinase
KNP414_RS15665	COG1653	transport
KNP414_RS15670	COG4209	transmembrane transport
KNP414_RS15675	COG0395	ABC-type sugar transport system, permease component
KNP414_RS15685	COG1404	Belongs to the peptidase S8 family
KNP414_RS15685	COG4935	Belongs to the peptidase S8 family
KNP414_RS15695	COG4303	Ethanolamine ammonia lyase large subunit
KNP414_RS15700	COG4302	ethanolamine ammonia-lyase activity
KNP414_RS15735	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KNP414_RS15740	COG0765	amino acid transport
KNP414_RS15745	COG0765	amino acid transport
KNP414_RS15750	COG1126	abc transporter atp-binding protein
KNP414_RS15755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNP414_RS15770	COG1408	metallophosphoesterase
KNP414_RS15865	COG0730	response to heat
KNP414_RS15870	COG1494	fructose-1,6-bisphosphatase
KNP414_RS15875	COG0517	IMP dehydrogenase activity
KNP414_RS15885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KNP414_RS15890	COG2258	MOSC domain
KNP414_RS15895	COG0746	molybdenum cofactor guanylyltransferase activity
KNP414_RS15900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KNP414_RS15905	COG0303	'Molybdopterin
KNP414_RS15910	COG0741	lytic transglycosylase activity
KNP414_RS15910	COG0791	NLP P60 protein
KNP414_RS15920	COG1595	DNA-templated transcription, initiation
KNP414_RS15955	COG1842	Phage shock protein A
KNP414_RS15965	COG1842	Phage shock protein A
KNP414_RS15970	COG4758	membrane
KNP414_RS15975	COG4585	Histidine kinase
KNP414_RS15980	COG2197	response regulator
KNP414_RS16015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KNP414_RS16020	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KNP414_RS16030	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KNP414_RS16035	COG0297	glycogen (starch) synthase activity
KNP414_RS16050	COG0673	inositol 2-dehydrogenase activity
KNP414_RS16070	COG0569	domain protein
KNP414_RS16075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNP414_RS16080	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KNP414_RS16085	COG2217	Heavy metal translocating P-type atpase
KNP414_RS16100	COG0745	RESPONSE REGULATOR receiver
KNP414_RS16105	COG5002	protein histidine kinase activity
KNP414_RS16125	COG2211	Major facilitator Superfamily
KNP414_RS16130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNP414_RS16135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KNP414_RS16140	COG1122	ATPase activity
KNP414_RS16155	COG0310	cobalt ion transport
KNP414_RS16165	COG0601	transmembrane transport
KNP414_RS16210	COG1609	Transcriptional regulator
KNP414_RS16215	COG2182	Extracellular solute-binding protein
KNP414_RS16230	COG1621	beta-fructofuranosidase activity
KNP414_RS16235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KNP414_RS16240	COG4989	oxidoreductase activity
KNP414_RS16245	COG0604	alcohol dehydrogenase
KNP414_RS16265	COG2197	response regulator
KNP414_RS16270	COG0028	Belongs to the TPP enzyme family
KNP414_RS16275	COG0440	acetolactate synthase activity
KNP414_RS16280	COG0640	Transcriptional regulator
KNP414_RS16285	COG0583	DNA-binding transcription factor activity
KNP414_RS16300	COG0739	heme binding
KNP414_RS16305	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KNP414_RS16310	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KNP414_RS16315	COG1691	(AIR) carboxylase
KNP414_RS16320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KNP414_RS16325	COG4470	Protein conserved in bacteria
KNP414_RS16350	COG3314	Sporulation integral membrane protein YlbJ
KNP414_RS16355	COG2346	COG2346, Truncated hemoglobins
KNP414_RS16370	COG3093	addiction module antidote protein HigA
KNP414_RS16415	COG0701	Predicted permease
KNP414_RS16425	COG0180	Tryptophanyl-tRNA synthetase
KNP414_RS16440	COG1988	membrane-bound metal-dependent
KNP414_RS16450	COG1132	(ABC) transporter
KNP414_RS16455	COG1132	(ABC) transporter
KNP414_RS16465	COG2723	6-phospho-beta-galactosidase activity
KNP414_RS16475	COG3250	beta-galactosidase activity
KNP414_RS16515	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KNP414_RS16520	COG2032	superoxide dismutase activity
KNP414_RS16525	COG0667	Aldo Keto reductase
KNP414_RS16545	COG1227	inorganic diphosphatase activity
KNP414_RS16555	COG2116	formate transmembrane transporter activity
KNP414_RS16560	COG0039	L-malate dehydrogenase activity
KNP414_RS16590	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS16595	COG0656	L-ascorbic acid biosynthetic process
KNP414_RS16605	COG0411	ABC transporter
KNP414_RS16625	COG0831	urea catabolic process
KNP414_RS16630	COG0832	Belongs to the urease beta subunit family
KNP414_RS16635	COG0804	urea catabolic process
KNP414_RS16640	COG0830	nickel cation binding
KNP414_RS16645	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KNP414_RS16650	COG0829	nickel cation binding
KNP414_RS16655	COG0109	protoheme IX farnesyltransferase activity
KNP414_RS16660	COG1999	signal sequence binding
KNP414_RS16700	COG0768	penicillin binding
KNP414_RS16705	COG0768	penicillin binding
KNP414_RS16710	COG0803	Belongs to the bacterial solute-binding protein 9 family
KNP414_RS16715	COG1121	(ABC) transporter
KNP414_RS16720	COG1321	iron dependent repressor
KNP414_RS16720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KNP414_RS16725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KNP414_RS16735	COG0367	asparagine synthase
KNP414_RS16740	COG0561	phosphatase activity
KNP414_RS16745	COG2839	Protein conserved in bacteria
KNP414_RS16750	COG2244	polysaccharide biosynthetic process
KNP414_RS16780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNP414_RS16785	COG1612	heme a metabolic process
KNP414_RS16800	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS16805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KNP414_RS16815	COG1252	NADH dehydrogenase
KNP414_RS16820	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KNP414_RS16830	COG0316	Belongs to the HesB IscA family
KNP414_RS16850	COG1252	NADH dehydrogenase
KNP414_RS16860	COG3858	chitin binding
KNP414_RS16865	COG3253	May function as heme-dependent peroxidase
KNP414_RS16880	COG1484	DNA-dependent DNA replication
KNP414_RS16885	COG3118	belongs to the thioredoxin family
KNP414_RS16890	COG0322	excinuclease ABC activity
KNP414_RS16900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KNP414_RS16905	COG0569	domain protein
KNP414_RS16910	COG3263	regulation of cellular component size
KNP414_RS16920	COG2009	succinate dehydrogenase
KNP414_RS16925	COG1053	succinate dehydrogenase
KNP414_RS16930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KNP414_RS16935	COG1609	Transcriptional regulator
KNP414_RS16980	COG1113	amino acid transport
KNP414_RS16985	COG4753	response regulator
KNP414_RS16985	COG2207	Transcriptional regulator
KNP414_RS16990	COG2972	Histidine kinase
KNP414_RS16995	COG4209	transmembrane transport
KNP414_RS17000	COG0395	ABC-type sugar transport system, permease component
KNP414_RS17020	COG0673	inositol 2-dehydrogenase activity
KNP414_RS17025	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KNP414_RS17035	COG4209	transmembrane transport
KNP414_RS17040	COG0395	ABC-type sugar transport system, permease component
KNP414_RS17045	COG1653	transport
KNP414_RS17065	COG2357	RelA SpoT domain protein
KNP414_RS17075	COG1396	sequence-specific DNA binding
KNP414_RS17085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS17090	COG2814	Major facilitator Superfamily
KNP414_RS17100	COG1272	protein, Hemolysin III
KNP414_RS17105	COG1349	DNA-binding transcription factor activity
KNP414_RS17110	COG3842	ATPase activity
KNP414_RS17120	COG0395	ABC-type sugar transport system, permease component
KNP414_RS17130	COG0584	glycerophosphoryl diester phosphodiesterase
KNP414_RS17150	COG1653	transport
KNP414_RS17155	COG0395	ABC-type sugar transport system, permease component
KNP414_RS17160	COG4209	transmembrane transport
KNP414_RS17175	COG0456	acetyltransferase
KNP414_RS17180	COG2311	Membrane
KNP414_RS17185	COG2169	Transcriptional regulator
KNP414_RS17190	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS17195	COG1595	DNA-templated transcription, initiation
KNP414_RS17215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KNP414_RS17220	COG1522	sequence-specific DNA binding
KNP414_RS17240	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KNP414_RS17280	COG1733	regulation of RNA biosynthetic process
KNP414_RS17285	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNP414_RS17295	COG0300	oxidoreductase activity
KNP414_RS17300	COG0789	Transcriptional regulator
KNP414_RS17320	COG2207	Transcriptional regulator
KNP414_RS17320	COG3708	Transcriptional regulator
KNP414_RS17350	COG4209	transmembrane transport
KNP414_RS17355	COG0395	ABC-type sugar transport system, permease component
KNP414_RS17360	COG1653	transport
KNP414_RS17385	COG0395	ABC-type sugar transport system, permease component
KNP414_RS17390	COG2723	6-phospho-beta-galactosidase activity
KNP414_RS17400	COG2197	response regulator
KNP414_RS17405	COG3275	phosphorelay sensor kinase activity
KNP414_RS17415	COG2273	Hydrolase Family 16
KNP414_RS17420	COG3214	Protein conserved in bacteria
KNP414_RS17450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KNP414_RS17470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KNP414_RS17475	COG0613	PHP domain protein
KNP414_RS17480	COG0583	DNA-binding transcription factor activity
KNP414_RS17490	COG4471	UPF0298 protein
KNP414_RS17510	COG1061	Type III restriction enzyme res subunit
KNP414_RS17520	COG0018	arginyl-trna synthetase
KNP414_RS17525	COG0673	inositol 2-dehydrogenase activity
KNP414_RS17530	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KNP414_RS17535	COG1473	amidohydrolase
KNP414_RS17545	COG0772	Belongs to the SEDS family
KNP414_RS17555	COG0387	Pfam Sodium calcium exchanger
KNP414_RS17560	COG4838	Belongs to the UPF0358 family
KNP414_RS17570	COG2309	aminopeptidase activity
KNP414_RS17580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KNP414_RS17590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNP414_RS17595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KNP414_RS17600	COG0454	-acetyltransferase
KNP414_RS17605	COG0123	including yeast histone deacetylase and acetoin utilization protein
KNP414_RS17610	COG0423	glycine-tRNA ligase activity
KNP414_RS17615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KNP414_RS17620	COG1609	Transcriptional regulator
KNP414_RS17640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNP414_RS17645	COG2190	(PTS) system
KNP414_RS17645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNP414_RS17645	COG1263	PTS System
KNP414_RS17655	COG0352	thiamine-phosphate diphosphorylase activity
KNP414_RS17660	COG1832	CoA-binding protein
KNP414_RS17670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KNP414_RS17675	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNP414_RS17680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNP414_RS17685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNP414_RS17690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KNP414_RS17700	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KNP414_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS17710	COG1070	Carbohydrate kinase
KNP414_RS17720	COG1609	Transcriptional regulator
KNP414_RS17745	COG4493	Belongs to the UPF0637 family
KNP414_RS17775	COG0395	ABC-type sugar transport system, permease component
KNP414_RS17780	COG4209	transmembrane transport
KNP414_RS17785	COG1653	transport
KNP414_RS17790	COG1309	transcriptional regulator
KNP414_RS17795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNP414_RS17805	COG1982	Orn Lys Arg decarboxylase major
KNP414_RS17820	COG0561	phosphatase activity
KNP414_RS17830	COG3906	Belongs to the UPF0473 family
KNP414_RS17840	COG0321	lipoyl(octanoyl) transferase activity
KNP414_RS17840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KNP414_RS17865	COG0840	transmembrane signaling receptor activity
KNP414_RS17870	COG3852	Histidine kinase
KNP414_RS17875	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KNP414_RS17885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNP414_RS17920	COG1793	dna ligase
KNP414_RS17925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KNP414_RS17945	COG0346	lactoylglutathione lyase activity
KNP414_RS18000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KNP414_RS18005	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KNP414_RS18020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KNP414_RS18040	COG0577	efflux transmembrane transporter activity
KNP414_RS18040	COG1136	(ABC) transporter
KNP414_RS18050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KNP414_RS18055	COG1136	(ABC) transporter
KNP414_RS18055	COG0577	efflux transmembrane transporter activity
KNP414_RS18060	COG0840	transmembrane signaling receptor activity
KNP414_RS18065	COG3935	DnaD domain protein
KNP414_RS18070	COG0017	Asparaginyl-tRNA synthetase
KNP414_RS18075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KNP414_RS18080	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNP414_RS18085	COG0066	3-isopropylmalate dehydratase activity
KNP414_RS18090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNP414_RS18095	COG0583	DNA-binding transcription factor activity
KNP414_RS18100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KNP414_RS18105	COG0436	Aminotransferase
KNP414_RS18115	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KNP414_RS18130	COG1850	ribulose-bisphosphate carboxylase activity
KNP414_RS18135	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KNP414_RS18140	COG0235	Class ii aldolase
KNP414_RS18150	COG1131	(ABC) transporter
KNP414_RS18160	COG1595	DNA-templated transcription, initiation
KNP414_RS18165	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KNP414_RS18175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KNP414_RS18185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KNP414_RS18190	COG0540	Belongs to the ATCase OTCase family
KNP414_RS18195	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KNP414_RS18205	COG1473	amidohydrolase
KNP414_RS18210	COG0436	Aminotransferase
KNP414_RS18215	COG0564	pseudouridine synthase activity
KNP414_RS18220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KNP414_RS18235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KNP414_RS18240	COG3599	regulation of cell shape
KNP414_RS18245	COG2302	S4 RNA-binding domain
KNP414_RS18255	COG1799	cell septum assembly
KNP414_RS18260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KNP414_RS18270	COG1873	PFAM PRC-barrel domain
KNP414_RS18275	COG1191	sigma factor activity
KNP414_RS18280	COG1191	sigma factor activity
KNP414_RS18290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KNP414_RS18295	COG0849	cell division
KNP414_RS18300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KNP414_RS18305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNP414_RS18315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KNP414_RS18320	COG0772	Belongs to the SEDS family
KNP414_RS18325	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KNP414_RS18330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNP414_RS18335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KNP414_RS18345	COG0768	penicillin binding
KNP414_RS18350	COG0768	penicillin binding
KNP414_RS18360	COG0275	rRNA processing
KNP414_RS18365	COG2001	Belongs to the MraZ family
KNP414_RS18375	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KNP414_RS18380	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KNP414_RS18390	COG4608	Belongs to the ABC transporter superfamily
KNP414_RS18395	COG0444	Belongs to the ABC transporter superfamily
KNP414_RS18400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNP414_RS18405	COG0601	transmembrane transport
KNP414_RS18410	COG4166	transmembrane transport
KNP414_RS18455	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KNP414_RS18485	COG1217	gtp-binding protein TYPA
KNP414_RS18490	COG0861	Integral membrane protein TerC family
KNP414_RS18495	COG0301	tRNA thio-modification
KNP414_RS18500	COG1104	cysteine desulfurase activity
KNP414_RS18505	COG0741	lytic transglycosylase activity
KNP414_RS18510	COG4709	membrane
KNP414_RS18530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KNP414_RS18535	COG2384	SAM-dependent methyltransferase
KNP414_RS18550	COG0358	DNA primase activity
KNP414_RS18555	COG1671	Belongs to the UPF0178 family
KNP414_RS18560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KNP414_RS18565	COG1381	Involved in DNA repair and RecF pathway recombination
KNP414_RS18570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KNP414_RS18580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KNP414_RS18585	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KNP414_RS18590	COG1480	7TM receptor with intracellular HD hydrolase
KNP414_RS18595	COG1702	phosphate starvation-inducible protein PhoH
KNP414_RS18615	COG4864	UPF0365 protein
KNP414_RS18625	COG1610	YqeY-like protein
KNP414_RS18630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KNP414_RS18635	COG0537	adenosine 5'-monophosphoramidase activity
KNP414_RS18650	COG0419	ATPase involved in DNA repair
KNP414_RS18655	COG0419	ATPase involved in DNA repair
KNP414_RS18660	COG0420	3'-5' exonuclease activity
KNP414_RS18665	COG1074	ATP-dependent DNA helicase activity
KNP414_RS18670	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KNP414_RS18695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KNP414_RS18700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KNP414_RS18705	COG1994	Peptidase M50
KNP414_RS18735	COG0459	protein refolding
KNP414_RS18740	COG1420	regulation of RNA biosynthetic process
KNP414_RS18750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KNP414_RS18755	COG0481	GTPase activity
KNP414_RS18775	COG0840	transmembrane signaling receptor activity
KNP414_RS18780	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KNP414_RS18785	COG0268	Binds directly to 16S ribosomal RNA
KNP414_RS18790	COG1466	dna polymerase III delta subunit
KNP414_RS18800	COG1595	DNA-templated transcription, initiation
KNP414_RS18815	COG2116	formate transmembrane transporter activity
KNP414_RS18820	COG2146	nitrite reductase [NAD(P)H] activity
KNP414_RS18825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNP414_RS18830	COG0658	competence protein
KNP414_RS18830	COG2333	competence protein COMEC
KNP414_RS18845	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNP414_RS18850	COG0495	leucyl-tRNA aminoacylation
KNP414_RS18855	COG2226	methyltransferase
KNP414_RS18860	COG2996	Protein conserved in bacteria
KNP414_RS18865	COG0799	negative regulation of ribosome biogenesis
KNP414_RS18870	COG1713	HD superfamily hydrolase involved in NAD metabolism
KNP414_RS18875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KNP414_RS18880	COG1534	Rna-binding protein
KNP414_RS18885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KNP414_RS18890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KNP414_RS18895	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KNP414_RS18900	COG3546	catalase activity
KNP414_RS18915	COG1305	Transglutaminase-like
KNP414_RS18925	COG0714	Associated with various cellular activities
KNP414_RS18935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNP414_RS18945	COG2323	membrane
KNP414_RS18965	COG0318	PFAM AMP-dependent synthetase and ligase
KNP414_RS18965	COG0204	Acyl-transferase
KNP414_RS18970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNP414_RS18975	COG2201	protein-glutamate methylesterase activity
KNP414_RS19000	COG4106	trans-aconitate 2-methyltransferase activity
KNP414_RS19030	COG3328	transposase activity
KNP414_RS19045	COG3250	beta-galactosidase activity
KNP414_RS19060	COG3250	beta-galactosidase activity
KNP414_RS19075	COG3507	Belongs to the glycosyl hydrolase 43 family
KNP414_RS19085	COG1472	Belongs to the glycosyl hydrolase 3 family
KNP414_RS19095	COG0395	ABC-type sugar transport system, permease component
KNP414_RS19100	COG4209	transmembrane transport
KNP414_RS19110	COG2207	Transcriptional regulator
KNP414_RS19110	COG4753	response regulator
KNP414_RS19115	COG2972	Histidine kinase
KNP414_RS19135	COG0395	ABC-type sugar transport system, permease component
KNP414_RS19140	COG1175	transmembrane transport
KNP414_RS19165	COG1175	transmembrane transport
KNP414_RS19170	COG1653	transport
KNP414_RS19220	COG2909	trisaccharide binding
KNP414_RS19270	COG0456	acetyltransferase
KNP414_RS19275	COG3250	beta-galactosidase activity
KNP414_RS19280	COG0395	ABC-type sugar transport system, permease component
KNP414_RS19285	COG4209	transmembrane transport
KNP414_RS19290	COG1653	transport
KNP414_RS19355	COG1846	Transcriptional regulator
KNP414_RS19375	COG0395	ABC-type sugar transport system, permease component
KNP414_RS19380	COG4209	transmembrane transport
KNP414_RS19385	COG3292	Two component regulator propeller
KNP414_RS19385	COG2205	protein histidine kinase activity
KNP414_RS19385	COG0745	RESPONSE REGULATOR receiver
KNP414_RS19410	COG0024	Methionine aminopeptidase
KNP414_RS19420	COG2318	DinB family
KNP414_RS19430	COG0529	Catalyzes the synthesis of activated sulfate
KNP414_RS19440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KNP414_RS19475	COG1132	(ABC) transporter
KNP414_RS19475	COG2375	cellular response to nickel ion
KNP414_RS19495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KNP414_RS19540	COG2378	regulation of single-species biofilm formation
KNP414_RS19550	COG0583	DNA-binding transcription factor activity
KNP414_RS19560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KNP414_RS19570	COG1960	acyl-CoA dehydrogenase activity
KNP414_RS19575	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS19590	COG2207	Transcriptional regulator
KNP414_RS19590	COG4753	response regulator
KNP414_RS19595	COG2972	Histidine kinase
KNP414_RS19600	COG0395	ABC-type sugar transport system, permease component
KNP414_RS19605	COG4209	transmembrane transport
KNP414_RS19610	COG1653	transport
KNP414_RS19620	COG0395	ABC-type sugar transport system, permease component
KNP414_RS19625	COG4209	transmembrane transport
KNP414_RS19635	COG2207	Transcriptional regulator
KNP414_RS19635	COG4753	response regulator
KNP414_RS19640	COG2972	Histidine kinase
KNP414_RS19645	COG4753	response regulator
KNP414_RS19645	COG2207	Transcriptional regulator
KNP414_RS19650	COG4753	response regulator
KNP414_RS19650	COG2207	Transcriptional regulator
KNP414_RS19655	COG2972	Histidine kinase
KNP414_RS19665	COG3507	Belongs to the glycosyl hydrolase 43 family
KNP414_RS19680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KNP414_RS19710	COG1178	ABC-type Fe3 transport system permease component
KNP414_RS19720	COG1840	ABC-type Fe3 transport system, periplasmic component
KNP414_RS19730	COG1609	Transcriptional regulator
KNP414_RS19735	COG1733	regulation of RNA biosynthetic process
KNP414_RS19740	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNP414_RS19745	COG1653	transport
KNP414_RS19750	COG4753	response regulator
KNP414_RS19750	COG2207	Transcriptional regulator
KNP414_RS19755	COG2972	Histidine kinase
KNP414_RS19760	COG1653	transport
KNP414_RS19765	COG3250	beta-galactosidase activity
KNP414_RS19775	COG0395	ABC-type sugar transport system, permease component
KNP414_RS19780	COG1175	transmembrane transport
KNP414_RS19785	COG1653	transport
KNP414_RS19805	COG1408	metallophosphoesterase
KNP414_RS19810	COG1309	transcriptional regulator
KNP414_RS19815	COG4221	oxidoreductase activity
KNP414_RS19825	COG3428	Bacterial PH domain
KNP414_RS19830	COG3402	PFAM membrane-flanked domain
KNP414_RS19835	COG2207	Transcriptional regulator
KNP414_RS19855	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS19875	COG3340	Belongs to the peptidase S51 family
KNP414_RS19895	COG2207	Transcriptional regulator
KNP414_RS19900	COG1846	Transcriptional regulator
KNP414_RS19905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KNP414_RS19915	COG3507	Belongs to the glycosyl hydrolase 43 family
KNP414_RS19925	COG2207	Transcriptional regulator
KNP414_RS19930	COG0346	lactoylglutathione lyase activity
KNP414_RS19935	COG0640	Transcriptional regulator
KNP414_RS19950	COG0574	Belongs to the PEP-utilizing enzyme family
KNP414_RS19950	COG3848	Pyruvate phosphate dikinase
KNP414_RS19970	COG0477	Major facilitator Superfamily
KNP414_RS19975	COG1733	regulation of RNA biosynthetic process
KNP414_RS19985	COG4221	oxidoreductase activity
KNP414_RS20005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KNP414_RS20010	COG0583	DNA-binding transcription factor activity
KNP414_RS20020	COG0667	Aldo Keto reductase
KNP414_RS20045	COG2017	converts alpha-aldose to the beta-anomer
KNP414_RS20050	COG3507	Belongs to the glycosyl hydrolase 43 family
KNP414_RS20055	COG1653	transport
KNP414_RS20060	COG0395	ABC-type sugar transport system, permease component
KNP414_RS20065	COG4209	transmembrane transport
KNP414_RS20070	COG2207	Transcriptional regulator
KNP414_RS20080	COG0673	inositol 2-dehydrogenase activity
KNP414_RS20120	COG3209	COG3209 Rhs family protein
KNP414_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS20150	COG0657	acetylesterase activity
KNP414_RS20170	COG2746	aminoglycoside 3-N-acetyltransferase activity
KNP414_RS20175	COG2182	Extracellular solute-binding protein
KNP414_RS20180	COG1175	transmembrane transport
KNP414_RS20185	COG3833	ABC-type maltose transport systems, permease component
KNP414_RS20200	COG2267	carboxylic ester hydrolase activity
KNP414_RS20205	COG0488	(ABC) transporter
KNP414_RS20220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KNP414_RS20225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNP414_RS20230	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS20235	COG1233	COG1233 Phytoene dehydrogenase and related
KNP414_RS20250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNP414_RS20280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KNP414_RS20290	COG2197	response regulator
KNP414_RS20295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNP414_RS20315	COG1045	serine acetyltransferase
KNP414_RS20330	COG0569	domain protein
KNP414_RS20365	COG1653	transport
KNP414_RS20370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS20375	COG0778	Nitroreductase
KNP414_RS20380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS20385	COG0667	Aldo Keto reductase
KNP414_RS20395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS20405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS20410	COG1132	(ABC) transporter
KNP414_RS20415	COG1132	(ABC) transporter
KNP414_RS20420	COG0395	ABC-type sugar transport system, permease component
KNP414_RS20425	COG1175	transmembrane transport
KNP414_RS20440	COG0395	ABC-type sugar transport system, permease component
KNP414_RS20455	COG3842	ATPase activity
KNP414_RS20460	COG0247	lactate metabolic process
KNP414_RS20465	COG0277	FAD linked oxidase domain protein
KNP414_RS20470	COG3655	Transcriptional regulator
KNP414_RS20490	COG2311	Membrane
KNP414_RS20505	COG1846	Transcriptional regulator
KNP414_RS20540	COG0583	DNA-binding transcription factor activity
KNP414_RS20545	COG0477	Major facilitator Superfamily
KNP414_RS20555	COG1846	Transcriptional regulator
KNP414_RS20570	COG1522	sequence-specific DNA binding
KNP414_RS20580	COG1064	alcohol dehydrogenase
KNP414_RS20585	COG3961	Belongs to the TPP enzyme family
KNP414_RS20590	COG0586	Pfam SNARE associated Golgi protein
KNP414_RS20595	COG1653	transport
KNP414_RS20600	COG2972	Histidine kinase
KNP414_RS20605	COG1653	transport
KNP414_RS20610	COG0395	ABC-type sugar transport system, permease component
KNP414_RS20615	COG4209	transmembrane transport
KNP414_RS20620	COG2207	Transcriptional regulator
KNP414_RS20620	COG4753	response regulator
KNP414_RS20625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNP414_RS20630	COG0778	Nitroreductase
KNP414_RS20635	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS20650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KNP414_RS20655	COG0861	Integral membrane protein TerC family
KNP414_RS20665	COG1309	transcriptional regulator
KNP414_RS20690	COG0840	transmembrane signaling receptor activity
KNP414_RS20705	COG3708	Transcriptional regulator
KNP414_RS20705	COG2207	Transcriptional regulator
KNP414_RS20730	COG2329	Antibiotic biosynthesis monooxygenase
KNP414_RS20735	COG1695	Transcriptional regulator
KNP414_RS20745	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KNP414_RS20785	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KNP414_RS20790	COG3639	organic phosphonate transmembrane transporter activity
KNP414_RS20800	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KNP414_RS20810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KNP414_RS20815	COG2962	Rard protein
KNP414_RS20830	COG2207	Transcriptional regulator
KNP414_RS20835	COG1653	transport
KNP414_RS20840	COG0395	ABC-type sugar transport system, permease component
KNP414_RS20845	COG4209	transmembrane transport
KNP414_RS20855	COG2755	lipolytic protein G-D-S-L family
KNP414_RS20860	COG2207	Transcriptional regulator
KNP414_RS20860	COG3708	Transcriptional regulator
KNP414_RS20865	COG1063	alcohol dehydrogenase
KNP414_RS20875	COG1609	Transcriptional regulator
KNP414_RS20880	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS20890	COG1309	transcriptional regulator
KNP414_RS20910	COG0778	Nitroreductase
KNP414_RS20925	COG4447	cellulose binding
KNP414_RS20925	COG4733	cellulase activity
KNP414_RS20930	COG4124	Belongs to the glycosyl hydrolase 26 family
KNP414_RS20935	COG3507	Belongs to the glycosyl hydrolase 43 family
KNP414_RS20950	COG2223	nitrite transmembrane transporter activity
KNP414_RS20965	COG2819	hydrolase of the alpha beta superfamily
KNP414_RS20970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS20975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS20980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNP414_RS20985	COG2207	Transcriptional regulator
KNP414_RS20985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNP414_RS21005	COG2207	Transcriptional regulator
KNP414_RS21010	COG3866	Pectate lyase
KNP414_RS21015	COG3940	Belongs to the glycosyl hydrolase 43 family
KNP414_RS21020	COG1902	pentaerythritol trinitrate reductase activity
KNP414_RS21025	COG1132	(ABC) transporter
KNP414_RS21030	COG2814	Major facilitator Superfamily
KNP414_RS21035	COG0583	DNA-binding transcription factor activity
KNP414_RS21055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS21065	COG2175	clavaminate synthase activity
KNP414_RS21075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNP414_RS21085	COG0395	ABC-type sugar transport system, permease component
KNP414_RS21090	COG4209	transmembrane transport
KNP414_RS21095	COG2207	Transcriptional regulator
KNP414_RS21095	COG4753	response regulator
KNP414_RS21100	COG2972	Histidine kinase
KNP414_RS21115	COG2207	Transcriptional regulator
KNP414_RS21120	COG4124	Belongs to the glycosyl hydrolase 26 family
KNP414_RS21125	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KNP414_RS21135	COG2271	Major facilitator Superfamily
KNP414_RS21140	COG0277	FAD linked oxidase domain protein
KNP414_RS21160	COG0492	ferredoxin-NADP+ reductase activity
KNP414_RS21165	COG1959	2 iron, 2 sulfur cluster binding
KNP414_RS21170	COG2770	Histidine kinase
KNP414_RS21170	COG2205	protein histidine kinase activity
KNP414_RS21175	COG0745	RESPONSE REGULATOR receiver
KNP414_RS21185	COG0517	IMP dehydrogenase activity
KNP414_RS21190	COG0745	RESPONSE REGULATOR receiver
KNP414_RS21205	COG1131	(ABC) transporter
KNP414_RS21220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNP414_RS21225	COG0673	inositol 2-dehydrogenase activity
KNP414_RS21255	COG0673	inositol 2-dehydrogenase activity
KNP414_RS21265	COG1136	(ABC) transporter
KNP414_RS21270	COG0577	efflux transmembrane transporter activity
KNP414_RS21280	COG1136	(ABC) transporter
KNP414_RS21280	COG0577	efflux transmembrane transporter activity
KNP414_RS21300	COG1653	transport
KNP414_RS21310	COG1653	transport
KNP414_RS21325	COG0395	ABC-type sugar transport system, permease component
KNP414_RS21330	COG1175	transmembrane transport
KNP414_RS21395	COG3833	ABC-type maltose transport systems, permease component
KNP414_RS21400	COG4209	transmembrane transport
KNP414_RS21410	COG3842	ATPase activity
KNP414_RS21415	COG1073	alpha beta
KNP414_RS21420	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS21420	COG4977	sequence-specific DNA binding
KNP414_RS21455	COG3250	beta-galactosidase activity
KNP414_RS21465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNP414_RS21470	COG1454	alcohol dehydrogenase
KNP414_RS21480	COG3408	Glycogen debranching enzyme
KNP414_RS21485	COG0395	ABC-type sugar transport system, permease component
KNP414_RS21490	COG4209	transmembrane transport
KNP414_RS21495	COG2972	Histidine kinase
KNP414_RS21505	COG1653	transport
KNP414_RS21525	COG3250	beta-galactosidase activity
KNP414_RS21535	COG1850	ribulose-bisphosphate carboxylase activity
KNP414_RS21545	COG0800	Aldolase
KNP414_RS21550	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS21570	COG2207	Transcriptional regulator
KNP414_RS21575	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KNP414_RS21580	COG3958	Transketolase
KNP414_RS21585	COG3959	Transketolase, thiamine diphosphate binding domain
KNP414_RS21595	COG1609	Transcriptional regulator
KNP414_RS21605	COG1501	Belongs to the glycosyl hydrolase 31 family
KNP414_RS21610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KNP414_RS21640	COG0697	spore germination
KNP414_RS21645	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KNP414_RS21655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNP414_RS21675	COG1193	negative regulation of DNA recombination
KNP414_RS21710	COG0745	RESPONSE REGULATOR receiver
KNP414_RS21715	COG5002	protein histidine kinase activity
KNP414_RS21750	COG0583	DNA-binding transcription factor activity
KNP414_RS21755	COG1910	domain protein
KNP414_RS21760	COG0725	ABC transporter, periplasmic molybdate-binding protein
KNP414_RS21765	COG4149	molybdate abc transporter
KNP414_RS21785	COG2207	Transcriptional regulator
KNP414_RS21795	COG1653	transport
KNP414_RS21800	COG0395	ABC-type sugar transport system, permease component
KNP414_RS21805	COG4209	transmembrane transport
KNP414_RS21815	COG2124	cytochrome p450
KNP414_RS21830	COG0745	RESPONSE REGULATOR receiver
KNP414_RS21835	COG2205	protein histidine kinase activity
KNP414_RS21860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KNP414_RS21865	COG0583	DNA-binding transcription factor activity
KNP414_RS21905	COG0667	Aldo Keto reductase
KNP414_RS21910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNP414_RS21915	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNP414_RS21940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNP414_RS21945	COG0395	ABC-type sugar transport system, permease component
KNP414_RS21950	COG1175	transmembrane transport
KNP414_RS21960	COG2972	Histidine kinase
KNP414_RS21965	COG4753	response regulator
KNP414_RS21965	COG2207	Transcriptional regulator
KNP414_RS21970	COG0789	Transcriptional regulator
KNP414_RS21975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNP414_RS21980	COG1733	regulation of RNA biosynthetic process
KNP414_RS22005	COG1175	transmembrane transport
KNP414_RS22010	COG3833	ABC-type maltose transport systems, permease component
KNP414_RS22015	COG2972	Histidine kinase
KNP414_RS22020	COG2207	Transcriptional regulator
KNP414_RS22020	COG4753	response regulator
KNP414_RS22020	COG2207	Transcriptional regulator
KNP414_RS22020	COG4753	response regulator
KNP414_RS22030	COG0789	Transcriptional regulator
KNP414_RS22035	COG0697	spore germination
KNP414_RS22045	COG0395	ABC-type sugar transport system, permease component
KNP414_RS22050	COG4209	transmembrane transport
KNP414_RS22065	COG2972	Histidine kinase
KNP414_RS22070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KNP414_RS22080	COG2124	cytochrome p450
KNP414_RS22090	COG2814	Major facilitator Superfamily
KNP414_RS22095	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS22105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNP414_RS22120	COG2186	Transcriptional regulator
KNP414_RS22125	COG1929	Belongs to the glycerate kinase type-1 family
KNP414_RS22130	COG2084	Dehydrogenase
KNP414_RS22135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNP414_RS22145	COG2271	Major facilitator Superfamily
KNP414_RS22165	COG3708	Transcriptional regulator
KNP414_RS22165	COG2207	Transcriptional regulator
KNP414_RS22170	COG2211	Major facilitator Superfamily
KNP414_RS22175	COG2207	Transcriptional regulator
KNP414_RS22175	COG4753	response regulator
KNP414_RS22175	COG4753	response regulator
KNP414_RS22175	COG2207	Transcriptional regulator
KNP414_RS22180	COG3275	phosphorelay sensor kinase activity
KNP414_RS22195	COG2197	response regulator
KNP414_RS22200	COG2972	Histidine kinase
KNP414_RS22205	COG1653	transport
KNP414_RS22210	COG0395	ABC-type sugar transport system, permease component
KNP414_RS22215	COG4209	transmembrane transport
KNP414_RS22235	COG5297	Belongs to the glycosyl hydrolase family 6
KNP414_RS22240	COG0583	DNA-binding transcription factor activity
KNP414_RS22245	COG0697	spore germination
KNP414_RS22255	COG1357	PFAM Pentapeptide repeats (8 copies)
KNP414_RS22265	COG1733	regulation of RNA biosynthetic process
KNP414_RS22275	COG1733	regulation of RNA biosynthetic process
KNP414_RS22280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNP414_RS22285	COG4533	DNA binding
KNP414_RS22290	COG2211	Major facilitator Superfamily
KNP414_RS22300	COG0655	NAD(P)H dehydrogenase (quinone) activity
KNP414_RS22305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KNP414_RS22315	COG3958	Transketolase
KNP414_RS22325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KNP414_RS22330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KNP414_RS22335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KNP414_RS22355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KNP414_RS22360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNP414_RS22365	COG0601	transmembrane transport
KNP414_RS22370	COG4608	Belongs to the ABC transporter superfamily
KNP414_RS22375	COG0444	Belongs to the ABC transporter superfamily
KNP414_RS22380	COG1473	amidohydrolase
KNP414_RS22385	COG0747	negative chemotaxis
KNP414_RS22395	COG0395	ABC-type sugar transport system, permease component
KNP414_RS22400	COG1175	transmembrane transport
KNP414_RS22415	COG0165	Argininosuccinate lyase
KNP414_RS22430	COG2368	4-hydroxyphenylacetate
KNP414_RS22440	COG0395	ABC-type sugar transport system, permease component
KNP414_RS22445	COG1175	transmembrane transport
KNP414_RS22455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS22490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS22495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS22510	COG1473	amidohydrolase
KNP414_RS22515	COG0456	acetyltransferase
KNP414_RS22520	COG1126	abc transporter atp-binding protein
KNP414_RS22525	COG0765	amino acid transport
KNP414_RS22530	COG0765	amino acid transport
KNP414_RS22535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNP414_RS22545	COG4608	Belongs to the ABC transporter superfamily
KNP414_RS22550	COG0444	Belongs to the ABC transporter superfamily
KNP414_RS22555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNP414_RS22570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS22575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS22580	COG0583	DNA-binding transcription factor activity
KNP414_RS22595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KNP414_RS22605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNP414_RS22610	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KNP414_RS22625	COG3119	arylsulfatase activity
KNP414_RS22630	COG0395	ABC-type sugar transport system, permease component
KNP414_RS22635	COG4209	transmembrane transport
KNP414_RS22640	COG1653	transport
KNP414_RS22655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS22680	COG0346	lactoylglutathione lyase activity
KNP414_RS22685	COG3739	integral membrane protein
KNP414_RS22710	COG0640	Transcriptional regulator
KNP414_RS22715	COG2205	protein histidine kinase activity
KNP414_RS22720	COG0745	RESPONSE REGULATOR receiver
KNP414_RS22755	COG0395	ABC-type sugar transport system, permease component
KNP414_RS22765	COG2182	Extracellular solute-binding protein
KNP414_RS22770	COG2207	Transcriptional regulator
KNP414_RS22775	COG2972	Histidine kinase
KNP414_RS22780	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS22800	COG2207	Transcriptional regulator
KNP414_RS22800	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS22815	COG0697	spore germination
KNP414_RS22835	COG1760	l-serine dehydratase
KNP414_RS22840	COG1760	l-serine dehydratase
KNP414_RS22850	COG0667	Aldo Keto reductase
KNP414_RS22855	COG0697	spore germination
KNP414_RS22890	COG2884	Cell division ATP-binding protein ftsE
KNP414_RS22905	COG1045	serine acetyltransferase
KNP414_RS22975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KNP414_RS22990	COG1131	(ABC) transporter
KNP414_RS23025	COG3507	Belongs to the glycosyl hydrolase 43 family
KNP414_RS23035	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KNP414_RS23080	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KNP414_RS23080	COG1672	PFAM Archaeal ATPase
KNP414_RS23085	COG0534	Mate efflux family protein
KNP414_RS23090	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNP414_RS23095	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KNP414_RS23105	COG0542	response to heat
KNP414_RS23110	COG1653	transport
KNP414_RS23115	COG0840	transmembrane signaling receptor activity
KNP414_RS23125	COG0534	Mate efflux family protein
KNP414_RS23150	COG0697	spore germination
KNP414_RS23205	COG1132	(ABC) transporter
KNP414_RS23210	COG1132	(ABC) transporter
KNP414_RS23220	COG3552	Protein containing von Willebrand factor type A (VWA) domain
KNP414_RS23230	COG0714	Associated with various cellular activities
KNP414_RS23245	COG2318	DinB family
KNP414_RS23255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNP414_RS23255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNP414_RS23265	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KNP414_RS23270	COG0535	radical SAM domain protein
KNP414_RS23280	COG2151	metal-sulfur cluster biosynthetic enzyme
KNP414_RS23295	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KNP414_RS23325	COG0477	Major facilitator Superfamily
KNP414_RS23330	COG3173	Aminoglycoside phosphotransferase
KNP414_RS23335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KNP414_RS23360	COG4154	Belongs to the RbsD FucU family
KNP414_RS23375	COG1607	acyl-coa hydrolase
KNP414_RS23380	COG0583	DNA-binding transcription factor activity
KNP414_RS23390	COG2321	neutral zinc metallopeptidase
KNP414_RS23405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS23445	COG2207	Transcriptional regulator
KNP414_RS23480	COG0628	permease
KNP414_RS23490	COG0483	inositol monophosphate 1-phosphatase activity
KNP414_RS23500	COG0534	Mate efflux family protein
KNP414_RS23510	COG0596	Alpha beta hydrolase
KNP414_RS23515	COG3961	Belongs to the TPP enzyme family
KNP414_RS23525	COG2135	peptidase activity
KNP414_RS23545	COG0210	DNA helicase
KNP414_RS23550	COG0531	amino acid
KNP414_RS23555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNP414_RS23595	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KNP414_RS23610	COG3829	transcription factor binding
KNP414_RS23610	COG3290	protein histidine kinase activity
KNP414_RS23670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KNP414_RS23700	COG2972	Histidine kinase
KNP414_RS23710	COG0395	ABC-type sugar transport system, permease component
KNP414_RS23715	COG1175	transmembrane transport
KNP414_RS23725	COG1309	transcriptional regulator
KNP414_RS23730	COG2814	Major facilitator Superfamily
KNP414_RS23735	COG3142	Participates in the control of copper homeostasis
KNP414_RS23740	COG2732	(Barnase) inhibitor
KNP414_RS23750	COG0039	L-malate dehydrogenase activity
KNP414_RS23755	COG2116	formate transmembrane transporter activity
KNP414_RS23775	COG3424	synthase
KNP414_RS23790	COG0723	plastoquinol--plastocyanin reductase activity
KNP414_RS23790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KNP414_RS23795	COG1309	transcriptional regulator
KNP414_RS23800	COG0702	epimerase
KNP414_RS23805	COG3631	Ketosteroid isomerase-related protein
KNP414_RS23830	COG1361	Conserved repeat domain
KNP414_RS23835	COG4257	antibiotic catabolic process
KNP414_RS23840	COG1196	nuclear chromosome segregation
KNP414_RS23840	COG0741	lytic transglycosylase activity
KNP414_RS23840	COG0739	heme binding
KNP414_RS23850	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KNP414_RS23865	COG0697	spore germination
KNP414_RS23870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNP414_RS23895	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KNP414_RS23900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KNP414_RS23905	COG2169	Transcriptional regulator
KNP414_RS23910	COG2363	Small membrane protein
KNP414_RS23915	COG1764	response to oxidative stress
KNP414_RS23930	COG0477	Major facilitator Superfamily
KNP414_RS23945	COG0326	Molecular chaperone. Has ATPase activity
KNP414_RS23955	COG1562	ergosterol biosynthetic process
KNP414_RS23965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KNP414_RS23970	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS23980	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KNP414_RS23995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNP414_RS24005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KNP414_RS24010	COG2390	Transcriptional regulator
KNP414_RS24030	COG0095	Lipoate-protein ligase
KNP414_RS24045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS24050	COG0778	Nitroreductase
KNP414_RS24055	COG1959	2 iron, 2 sulfur cluster binding
KNP414_RS24065	COG3507	Belongs to the glycosyl hydrolase 43 family
KNP414_RS24070	COG3534	alpha-L-arabinofuranosidase
KNP414_RS24075	COG0395	ABC-type sugar transport system, permease component
KNP414_RS24080	COG1175	transmembrane transport
KNP414_RS24105	COG2755	lipolytic protein G-D-S-L family
KNP414_RS24105	COG3401	FG-GAP repeat protein
KNP414_RS24110	COG1475	DNA binding
KNP414_RS24115	COG0366	Alpha amylase catalytic
KNP414_RS24120	COG2208	phosphoserine phosphatase activity
KNP414_RS24125	COG0596	Alpha beta hydrolase
KNP414_RS24140	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KNP414_RS24190	COG3118	belongs to the thioredoxin family
KNP414_RS24195	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KNP414_RS24200	COG3401	FG-GAP repeat protein
KNP414_RS24205	COG1253	flavin adenine dinucleotide binding
KNP414_RS24215	COG1653	transport
KNP414_RS24220	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KNP414_RS24225	COG0477	Major facilitator Superfamily
KNP414_RS24235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNP414_RS24250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KNP414_RS24255	COG0006	proline dipeptidase activity
KNP414_RS24275	COG0697	spore germination
KNP414_RS24295	COG3153	acetyltransferase
KNP414_RS24340	COG1131	(ABC) transporter
KNP414_RS24345	COG0456	acetyltransferase
KNP414_RS24375	COG2208	phosphoserine phosphatase activity
KNP414_RS24400	COG1278	Cold shock
KNP414_RS24405	COG0705	Rhomboid family
KNP414_RS24430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KNP414_RS24435	COG1309	transcriptional regulator
KNP414_RS24455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNP414_RS24460	COG4608	Belongs to the ABC transporter superfamily
KNP414_RS24475	COG0601	transmembrane transport
KNP414_RS24480	COG0747	negative chemotaxis
KNP414_RS24500	COG1063	alcohol dehydrogenase
KNP414_RS24510	COG5577	PFAM Coat F domain
KNP414_RS24540	COG2719	SpoVR family
KNP414_RS24545	COG2718	Belongs to the UPF0229 family
KNP414_RS24550	COG2766	serine protein kinase
KNP414_RS24575	COG5002	protein histidine kinase activity
KNP414_RS24575	COG2198	Histidine kinase
KNP414_RS24575	COG0784	Response regulator, receiver
KNP414_RS24585	COG0346	lactoylglutathione lyase activity
KNP414_RS24595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNP414_RS24605	COG0626	cystathionine gamma-synthase activity
KNP414_RS24610	COG1428	Deoxynucleoside kinase
KNP414_RS24620	COG3300	MHYT domain
KNP414_RS24620	COG5001	Diguanylate cyclase
KNP414_RS24630	COG4166	transmembrane transport
KNP414_RS24675	COG2124	cytochrome p450
KNP414_RS24680	COG0659	secondary active sulfate transmembrane transporter activity
KNP414_RS24685	COG0288	reversible hydration of carbon dioxide
KNP414_RS24710	COG4474	Belongs to the UPF0398 family
KNP414_RS24740	COG0531	amino acid
KNP414_RS24760	COG0596	Alpha beta hydrolase
KNP414_RS24780	COG0534	Mate efflux family protein
KNP414_RS24790	COG1199	ATP-dependent helicase activity
KNP414_RS24805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNP414_RS24810	COG0601	transmembrane transport
KNP414_RS24820	COG4608	Belongs to the ABC transporter superfamily
KNP414_RS24825	COG0444	Belongs to the ABC transporter superfamily
KNP414_RS24830	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
KNP414_RS24865	COG4191	Histidine kinase
KNP414_RS24875	COG3842	ATPase activity
KNP414_RS24890	COG0667	Aldo Keto reductase
KNP414_RS24895	COG2318	DinB family
KNP414_RS24905	COG0640	Transcriptional regulator
KNP414_RS24925	COG2234	aminopeptidase activity
KNP414_RS24930	COG1472	Belongs to the glycosyl hydrolase 3 family
KNP414_RS24975	COG1309	transcriptional regulator
KNP414_RS24980	COG2814	Major facilitator Superfamily
KNP414_RS24995	COG1683	Conserved Protein
KNP414_RS25000	COG0488	(ABC) transporter
KNP414_RS25010	COG1959	2 iron, 2 sulfur cluster binding
KNP414_RS25020	COG1653	transport
KNP414_RS25025	COG0395	ABC-type sugar transport system, permease component
KNP414_RS25030	COG4209	transmembrane transport
KNP414_RS25040	COG2972	Histidine kinase
KNP414_RS25075	COG2124	cytochrome p450
KNP414_RS25095	COG0395	ABC-type sugar transport system, permease component
KNP414_RS25100	COG4209	transmembrane transport
KNP414_RS25110	COG2207	Transcriptional regulator
KNP414_RS25140	COG0697	spore germination
KNP414_RS25175	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KNP414_RS25180	COG0667	Aldo Keto reductase
KNP414_RS25200	COG4999	Histidine kinase
KNP414_RS25200	COG3850	Histidine kinase
KNP414_RS25200	COG3437	response regulator, receiver
KNP414_RS25200	COG2205	protein histidine kinase activity
KNP414_RS25210	COG0840	transmembrane signaling receptor activity
KNP414_RS25235	COG0531	amino acid
KNP414_RS25250	COG0697	spore germination
KNP414_RS25265	COG1063	alcohol dehydrogenase
KNP414_RS25280	COG0791	NLP P60 protein
KNP414_RS25290	COG1619	proteins homologs of microcin C7 resistance protein MccF
KNP414_RS25295	COG4166	transmembrane transport
KNP414_RS25300	COG0444	Belongs to the ABC transporter superfamily
KNP414_RS25305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNP414_RS25310	COG0601	transmembrane transport
KNP414_RS25315	COG2362	D-Aminopeptidase
KNP414_RS25325	COG4377	Putative membrane peptidase family (DUF2324)
KNP414_RS25330	COG3401	FG-GAP repeat protein
KNP414_RS25345	COG1653	transport
KNP414_RS25350	COG0395	ABC-type sugar transport system, permease component
KNP414_RS25355	COG4209	transmembrane transport
KNP414_RS25360	COG2207	Transcriptional regulator
KNP414_RS25375	COG2755	lipolytic protein G-D-S-L family
KNP414_RS25380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KNP414_RS25385	COG0395	ABC-type sugar transport system, permease component
KNP414_RS25390	COG1175	transmembrane transport
KNP414_RS25400	COG1653	transport
KNP414_RS25405	COG2207	Transcriptional regulator
KNP414_RS25405	COG4753	response regulator
KNP414_RS25410	COG2972	Histidine kinase
KNP414_RS25415	COG0561	phosphatase activity
KNP414_RS25420	COG1051	belongs to the nudix hydrolase family
KNP414_RS25430	COG2032	superoxide dismutase activity
KNP414_RS25450	COG1295	ribonuclease BN
KNP414_RS25455	COG2323	membrane
KNP414_RS25460	COG2205	protein histidine kinase activity
KNP414_RS25475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KNP414_RS25490	COG4129	membrane
KNP414_RS25495	COG0805	protein transport
KNP414_RS25500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KNP414_RS25520	COG1136	(ABC) transporter
KNP414_RS25525	COG1785	Belongs to the alkaline phosphatase family
KNP414_RS25530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KNP414_RS25535	COG1335	isochorismatase
KNP414_RS25540	COG3973	AAA domain
KNP414_RS25545	COG0456	acetyltransferase
KNP414_RS25550	COG1247	-acetyltransferase
KNP414_RS25595	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS25595	COG3507	Belongs to the glycosyl hydrolase 43 family
KNP414_RS25595	COG2382	esterase
KNP414_RS25610	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS25610	COG2207	Transcriptional regulator
KNP414_RS25615	COG2972	Histidine kinase
KNP414_RS25625	COG0395	ABC-type sugar transport system, permease component
KNP414_RS25630	COG4209	transmembrane transport
KNP414_RS25640	COG2205	protein histidine kinase activity
KNP414_RS25650	COG0697	spore germination
KNP414_RS25660	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KNP414_RS25665	COG2222	sugar isomerase
KNP414_RS25670	COG0252	asparaginase activity
KNP414_RS25675	COG1082	Xylose isomerase domain protein TIM barrel
KNP414_RS25680	COG0395	ABC-type sugar transport system, permease component
KNP414_RS25685	COG1175	transmembrane transport
KNP414_RS25690	COG1653	transport
KNP414_RS25695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNP414_RS25700	COG2188	Transcriptional regulator
KNP414_RS25705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KNP414_RS25715	COG1643	Atp-dependent helicase
KNP414_RS25735	COG4895	conserved protein (DUF2196)
KNP414_RS25755	COG2217	Heavy metal translocating P-type atpase
KNP414_RS25760	COG0864	Transcriptional regulator
KNP414_RS25765	COG4550	Control of competence regulator ComK, YlbF/YmcA
KNP414_RS25770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KNP414_RS25775	COG4869	propanediol catabolic process
KNP414_RS25780	COG1013	pyruvate-flavodoxin oxidoreductase activity
KNP414_RS25785	COG0674	pyruvate-flavodoxin oxidoreductase activity
KNP414_RS25785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KNP414_RS25795	COG2359	stage V sporulation protein S
KNP414_RS25800	COG1692	metallophosphoesterase
KNP414_RS25805	COG1418	mRNA catabolic process
KNP414_RS25810	COG2137	regulation of response to DNA damage stimulus
KNP414_RS25815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KNP414_RS25820	COG1546	Belongs to the CinA family
KNP414_RS25820	COG1058	Belongs to the CinA family
KNP414_RS25825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KNP414_RS25830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KNP414_RS25845	COG1426	Protein conserved in bacteria
KNP414_RS25865	COG0300	oxidoreductase activity
KNP414_RS25870	COG0612	Peptidase, M16
KNP414_RS25875	COG0612	Peptidase, M16
KNP414_RS25885	COG1674	ftsk spoiiie
KNP414_RS25895	COG0740	serine-type endopeptidase activity
KNP414_RS25900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNP414_RS25910	COG0527	aspartate kinase activity
KNP414_RS25915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KNP414_RS25920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KNP414_RS25925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNP414_RS25930	COG0756	dUTP diphosphatase activity
KNP414_RS25935	COG0612	Peptidase, M16
KNP414_RS25940	COG0726	polysaccharide deacetylase
KNP414_RS25945	COG1185	polyribonucleotide nucleotidyltransferase activity
KNP414_RS25950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KNP414_RS25955	COG0196	riboflavin kinase activity
KNP414_RS25960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KNP414_RS25965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KNP414_RS25970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KNP414_RS25975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KNP414_RS25980	COG1358	cellular component organization or biogenesis
KNP414_RS25990	COG0195	Participates in both transcription termination and antitermination
KNP414_RS25995	COG0779	Required for maturation of 30S ribosomal subunits
KNP414_RS26000	COG2176	DNA-directed DNA polymerase activity
KNP414_RS26005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNP414_RS26010	COG0750	zinc metalloprotease
KNP414_RS26015	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KNP414_RS26020	COG4589	Belongs to the CDS family
KNP414_RS26025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KNP414_RS26030	COG0233	cytoplasmic translational termination
KNP414_RS26035	COG0528	UMP kinase activity
KNP414_RS26040	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KNP414_RS26045	COG0052	Belongs to the universal ribosomal protein uS2 family
KNP414_RS26070	COG1191	sigma factor activity
KNP414_RS26080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KNP414_RS26085	COG1776	CheC inhibitor of MCP methylation
KNP414_RS26090	COG0835	chemotaxis
KNP414_RS26095	COG2198	Histidine kinase
KNP414_RS26095	COG0643	Histidine kinase
KNP414_RS26100	COG2201	protein-glutamate methylesterase activity
KNP414_RS26105	COG0455	bacterial-type flagellum organization
KNP414_RS26110	COG1419	protein localization to endoplasmic reticulum
KNP414_RS26115	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KNP414_RS26120	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KNP414_RS26125	COG1684	flagellar biosynthetic protein fliR
KNP414_RS26130	COG1987	bacterial-type flagellum assembly
KNP414_RS26135	COG1338	Plays a role in the flagellum-specific transport system
KNP414_RS26140	COG3190	flagellar
KNP414_RS26145	COG2201	protein-glutamate methylesterase activity
KNP414_RS26150	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KNP414_RS26150	COG1776	CheC inhibitor of MCP methylation
KNP414_RS26155	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KNP414_RS26165	COG1582	Flagellar protein (FlbD)
KNP414_RS26170	COG4786	Flagellar basal body rod
KNP414_RS26180	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KNP414_RS26185	COG3144	bacterial-type flagellum assembly
KNP414_RS26195	COG2882	bacterial-type flagellum organization
KNP414_RS26200	COG1157	protein secretion by the type III secretion system
KNP414_RS26210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KNP414_RS26215	COG1766	The M ring may be actively involved in energy transduction
KNP414_RS26220	COG1677	Flagellar hook-basal body complex protein FliE
KNP414_RS26225	COG1558	bacterial-type flagellum-dependent cell motility
KNP414_RS26230	COG1815	bacterial-type flagellum-dependent cell motility
KNP414_RS26235	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KNP414_RS26240	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KNP414_RS26245	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KNP414_RS26250	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KNP414_RS26255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KNP414_RS26260	COG0758	DNA mediated transformation
KNP414_RS26265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KNP414_RS26270	COG0045	succinate-CoA ligase (ADP-forming) activity
KNP414_RS26280	COG0606	chelatase, subunit chli
KNP414_RS26290	COG2257	FlhB HrpN YscU SpaS Family
KNP414_RS26300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNP414_RS26315	COG0681	Belongs to the peptidase S26 family
KNP414_RS26320	COG0335	large ribosomal subunit rRNA binding
KNP414_RS26345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KNP414_RS26355	COG0228	four-way junction DNA binding
KNP414_RS26360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KNP414_RS26365	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KNP414_RS26370	COG0552	protein localization to endoplasmic reticulum
KNP414_RS26375	COG1196	nuclear chromosome segregation
KNP414_RS26385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KNP414_RS26390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNP414_RS26395	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS26400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KNP414_RS26405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNP414_RS26410	COG0416	fatty acid biosynthetic process
KNP414_RS26415	COG1349	DNA-binding transcription factor activity
KNP414_RS26415	COG2050	protein possibly involved in aromatic compounds catabolism
KNP414_RS26425	COG1323	Belongs to the UPF0348 family
KNP414_RS26430	COG3480	Lon protease (S16) C-terminal proteolytic domain
KNP414_RS26440	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KNP414_RS26445	COG0742	ribosomal rna small subunit methyltransferase
KNP414_RS26455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNP414_RS26465	COG2755	lipolytic protein G-D-S-L family
KNP414_RS26475	COG0346	lactoylglutathione lyase activity
KNP414_RS26500	COG1904	glucuronate isomerase
KNP414_RS26515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNP414_RS26525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNP414_RS26530	COG1309	transcriptional regulator
KNP414_RS26540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KNP414_RS26545	COG1307	EDD domain protein, DegV family
KNP414_RS26550	COG1461	Dihydroxyacetone kinase
KNP414_RS26555	COG1302	Protein conserved in bacteria
KNP414_RS26560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KNP414_RS26575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KNP414_RS26580	COG1162	GTPase activity
KNP414_RS26585	COG2815	serine threonine protein kinase
KNP414_RS26585	COG0515	serine threonine protein kinase
KNP414_RS26590	COG0631	protein serine/threonine phosphatase activity
KNP414_RS26595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KNP414_RS26600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KNP414_RS26600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KNP414_RS26615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KNP414_RS26620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KNP414_RS26625	COG1758	RNA polymerase activity
KNP414_RS26630	COG0194	GDP metabolic process
KNP414_RS26635	COG2052	Domain of unknown function (DUF370)
KNP414_RS26640	COG1561	YicC-like family, N-terminal region
KNP414_RS26645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KNP414_RS26645	COG0646	methionine synthase
KNP414_RS26655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KNP414_RS26660	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KNP414_RS26680	COG1733	regulation of RNA biosynthetic process
KNP414_RS26685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KNP414_RS26700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KNP414_RS26705	COG3328	transposase activity
KNP414_RS26710	COG1733	regulation of RNA biosynthetic process
KNP414_RS26715	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS26755	COG3708	Transcriptional regulator
KNP414_RS26755	COG2207	Transcriptional regulator
KNP414_RS26765	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KNP414_RS26795	COG2322	membrane
KNP414_RS26815	COG0697	spore germination
KNP414_RS26835	COG0559	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS26845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNP414_RS26850	COG1653	transport
KNP414_RS26860	COG0395	ABC-type sugar transport system, permease component
KNP414_RS26865	COG1175	transmembrane transport
KNP414_RS26870	COG1653	transport
KNP414_RS26880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNP414_RS26890	COG0372	Belongs to the citrate synthase family
KNP414_RS26905	COG4974	Belongs to the 'phage' integrase family
KNP414_RS26915	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KNP414_RS26915	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KNP414_RS26920	COG0667	Aldo Keto reductase
KNP414_RS26930	COG0154	amidase activity
KNP414_RS26980	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KNP414_RS26985	COG0454	-acetyltransferase
KNP414_RS26990	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KNP414_RS27005	COG1695	Transcriptional regulator
KNP414_RS27015	COG1309	transcriptional regulator
KNP414_RS27020	COG3631	Ketosteroid isomerase-related protein
KNP414_RS27075	COG3328	transposase activity
KNP414_RS27105	COG3458	cephalosporin-C deacetylase activity
KNP414_RS27110	COG0840	transmembrane signaling receptor activity
KNP414_RS27115	COG1132	(ABC) transporter
KNP414_RS27120	COG1132	(ABC) transporter
KNP414_RS27125	COG1126	abc transporter atp-binding protein
KNP414_RS27130	COG0765	amino acid transport
KNP414_RS27135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNP414_RS27175	COG0584	glycerophosphoryl diester phosphodiesterase
KNP414_RS27180	COG0840	transmembrane signaling receptor activity
KNP414_RS27185	COG1744	ABC transporter substrate-binding protein PnrA-like
KNP414_RS27200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KNP414_RS27205	COG4999	Histidine kinase
KNP414_RS27205	COG3850	Histidine kinase
KNP414_RS27205	COG3437	response regulator, receiver
KNP414_RS27205	COG2205	protein histidine kinase activity
KNP414_RS27220	COG0583	DNA-binding transcription factor activity
KNP414_RS27225	COG0840	transmembrane signaling receptor activity
KNP414_RS27240	COG0318	PFAM AMP-dependent synthetase and ligase
KNP414_RS27245	COG1960	acyl-CoA dehydrogenase activity
KNP414_RS27250	COG0183	Belongs to the thiolase family
KNP414_RS27255	COG1024	Enoyl-CoA hydratase
KNP414_RS27255	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNP414_RS27260	COG0247	lactate metabolic process
KNP414_RS27260	COG2181	nitrate reductase activity
KNP414_RS27265	COG1309	transcriptional regulator
KNP414_RS27270	COG2086	electron transfer activity
KNP414_RS27275	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KNP414_RS27305	COG0673	inositol 2-dehydrogenase activity
KNP414_RS27310	COG0412	Dienelactone hydrolase
KNP414_RS27315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KNP414_RS27340	COG3290	protein histidine kinase activity
KNP414_RS27350	COG1280	lysine exporter protein (LysE YggA)
KNP414_RS27355	COG1113	amino acid transport
KNP414_RS27360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS27380	COG3940	Belongs to the glycosyl hydrolase 43 family
KNP414_RS27385	COG0395	ABC-type sugar transport system, permease component
KNP414_RS27390	COG1175	transmembrane transport
KNP414_RS27395	COG1653	transport
KNP414_RS27400	COG3940	Belongs to the glycosyl hydrolase 43 family
KNP414_RS27435	COG0673	inositol 2-dehydrogenase activity
KNP414_RS27445	COG1012	belongs to the aldehyde dehydrogenase family
KNP414_RS27450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNP414_RS27455	COG1082	Xylose isomerase domain protein TIM barrel
KNP414_RS27460	COG3962	Belongs to the TPP enzyme family
KNP414_RS27465	COG2207	Transcriptional regulator
KNP414_RS27465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNP414_RS27470	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KNP414_RS27475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS27480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS27490	COG1653	transport
KNP414_RS27500	COG0395	ABC-type sugar transport system, permease component
KNP414_RS27505	COG4209	transmembrane transport
KNP414_RS27510	COG2207	Transcriptional regulator
KNP414_RS27535	COG0457	Tetratricopeptide repeat
KNP414_RS27535	COG0463	Glycosyl transferase, family 2
KNP414_RS27555	COG1215	transferase activity, transferring glycosyl groups
KNP414_RS27560	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS27570	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS27580	COG3401	FG-GAP repeat protein
KNP414_RS27585	COG3693	PFAM glycoside hydrolase, family 10
KNP414_RS27585	COG2382	esterase
KNP414_RS27610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNP414_RS27620	COG2207	Transcriptional regulator
KNP414_RS27635	COG0596	Alpha beta hydrolase
KNP414_RS27645	COG1609	Transcriptional regulator
KNP414_RS27660	COG5297	Belongs to the glycosyl hydrolase family 6
KNP414_RS27700	COG0456	acetyltransferase
KNP414_RS27700	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KNP414_RS27705	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KNP414_RS27710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KNP414_RS27715	COG1122	ATPase activity
KNP414_RS27720	COG1122	ATPase activity
KNP414_RS27725	COG1268	BioY protein
KNP414_RS27730	COG3344	reverse transcriptase
KNP414_RS27745	COG2186	Transcriptional regulator
KNP414_RS27750	COG1556	Lactate utilization protein
KNP414_RS27755	COG1139	Iron-sulfur cluster binding protein
KNP414_RS27760	COG0247	lactate metabolic process
KNP414_RS27770	COG1349	DNA-binding transcription factor activity
KNP414_RS27775	COG1070	Carbohydrate kinase
KNP414_RS27780	COG4952	isomerase
KNP414_RS27790	COG3347	Dehydrogenase
KNP414_RS27790	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS27810	COG2814	Major facilitator Superfamily
KNP414_RS27820	COG4447	cellulose binding
KNP414_RS27820	COG5297	Belongs to the glycosyl hydrolase family 6
KNP414_RS27835	COG3534	alpha-L-arabinofuranosidase
KNP414_RS27840	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KNP414_RS27845	COG2755	lipolytic protein G-D-S-L family
KNP414_RS27890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KNP414_RS27895	COG1132	(ABC) transporter
KNP414_RS27900	COG3706	GGDEF domain
KNP414_RS27910	COG3940	Belongs to the glycosyl hydrolase 43 family
KNP414_RS27915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNP414_RS27920	COG0765	amino acid transport
KNP414_RS27925	COG1126	abc transporter atp-binding protein
KNP414_RS27935	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KNP414_RS27950	COG1940	carbohydrate kinase activity
KNP414_RS27960	COG0791	NLP P60 protein
KNP414_RS27960	COG1388	LysM domain
KNP414_RS27960	COG3103	Sh3 type 3 domain protein
KNP414_RS27965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNP414_RS27970	COG1960	acyl-CoA dehydrogenase activity
KNP414_RS27985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KNP414_RS28000	COG1733	regulation of RNA biosynthetic process
KNP414_RS28015	COG2217	Heavy metal translocating P-type atpase
KNP414_RS28040	COG0583	DNA-binding transcription factor activity
KNP414_RS28045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KNP414_RS28050	COG0833	amino acid
KNP414_RS28055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KNP414_RS28060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KNP414_RS28070	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNP414_RS28075	COG1733	regulation of RNA biosynthetic process
KNP414_RS28080	COG2207	Transcriptional regulator
KNP414_RS28085	COG3275	phosphorelay sensor kinase activity
KNP414_RS28095	COG0395	ABC-type sugar transport system, permease component
KNP414_RS28100	COG4209	transmembrane transport
KNP414_RS28125	COG4753	response regulator
KNP414_RS28125	COG2207	Transcriptional regulator
KNP414_RS28150	COG2318	DinB family
KNP414_RS28155	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS28165	COG0583	DNA-binding transcription factor activity
KNP414_RS28170	COG3275	phosphorelay sensor kinase activity
KNP414_RS28175	COG2207	Transcriptional regulator
KNP414_RS28175	COG4753	response regulator
KNP414_RS28185	COG0395	ABC-type sugar transport system, permease component
KNP414_RS28190	COG4209	transmembrane transport
KNP414_RS28205	COG1609	Transcriptional regulator
KNP414_RS28230	COG0395	ABC-type sugar transport system, permease component
KNP414_RS28235	COG4209	transmembrane transport
KNP414_RS28245	COG0300	oxidoreductase activity
KNP414_RS28260	COG2972	Histidine kinase
KNP414_RS28265	COG2207	Transcriptional regulator
KNP414_RS28265	COG4753	response regulator
KNP414_RS28270	COG1879	ABC-type sugar transport system periplasmic component
KNP414_RS28275	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS28285	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KNP414_RS28290	COG2207	Transcriptional regulator
KNP414_RS28295	COG4948	Mandelate Racemase Muconate Lactonizing
KNP414_RS28300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNP414_RS28305	COG1012	belongs to the aldehyde dehydrogenase family
KNP414_RS28310	COG1653	transport
KNP414_RS28315	COG0395	ABC-type sugar transport system, permease component
KNP414_RS28320	COG4209	transmembrane transport
KNP414_RS28325	COG4608	Belongs to the ABC transporter superfamily
KNP414_RS28335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNP414_RS28340	COG0601	transmembrane transport
KNP414_RS28345	COG0747	negative chemotaxis
KNP414_RS28365	COG1653	transport
KNP414_RS28370	COG2207	Transcriptional regulator
KNP414_RS28370	COG4753	response regulator
KNP414_RS28390	COG1136	(ABC) transporter
KNP414_RS28410	COG0395	ABC-type sugar transport system, permease component
KNP414_RS28415	COG4209	transmembrane transport
KNP414_RS28430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNP414_RS28435	COG1522	sequence-specific DNA binding
KNP414_RS28440	COG0456	acetyltransferase
KNP414_RS28440	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KNP414_RS28445	COG0737	Belongs to the 5'-nucleotidase family
KNP414_RS28445	COG1525	nuclease
KNP414_RS28445	COG4085	toxin activity
KNP414_RS28455	COG2197	response regulator
KNP414_RS28470	COG0318	PFAM AMP-dependent synthetase and ligase
KNP414_RS28505	COG1309	transcriptional regulator
KNP414_RS28515	COG3706	GGDEF domain
KNP414_RS28555	COG0095	Lipoate-protein ligase
KNP414_RS28580	COG0745	RESPONSE REGULATOR receiver
KNP414_RS28610	COG5002	protein histidine kinase activity
KNP414_RS28615	COG0768	penicillin binding
KNP414_RS28620	COG0840	transmembrane signaling receptor activity
KNP414_RS28625	COG0826	peptidase U32
KNP414_RS28630	COG0826	peptidase U32
KNP414_RS28635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KNP414_RS28650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KNP414_RS28655	COG4472	Bacterial protein of unknown function (DUF965)
KNP414_RS28675	COG0697	spore germination
KNP414_RS28680	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KNP414_RS28690	COG0628	permease
KNP414_RS28705	COG1104	cysteine desulfurase activity
KNP414_RS28710	COG1959	2 iron, 2 sulfur cluster binding
KNP414_RS28715	COG0482	sulfurtransferase activity
KNP414_RS28720	COG1253	flavin adenine dinucleotide binding
KNP414_RS28730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KNP414_RS28735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KNP414_RS28740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KNP414_RS28745	COG0124	histidyl-tRNA synthetase
KNP414_RS28760	COG1490	D-aminoacyl-tRNA deacylase activity
KNP414_RS28765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNP414_RS28770	COG5337	Spore coat protein CotH
KNP414_RS28790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNP414_RS28795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KNP414_RS28795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KNP414_RS28800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KNP414_RS28815	COG2244	polysaccharide biosynthetic process
KNP414_RS28820	COG2323	membrane
KNP414_RS28830	COG1862	Preprotein translocase
KNP414_RS28845	COG2385	sporulation resulting in formation of a cellular spore
KNP414_RS28850	COG2255	four-way junction helicase activity
KNP414_RS28855	COG0632	four-way junction helicase activity
KNP414_RS28860	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KNP414_RS28875	COG0681	Belongs to the peptidase S26 family
KNP414_RS28880	COG1388	LysM domain
KNP414_RS28880	COG0860	N-Acetylmuramoyl-L-alanine amidase
KNP414_RS28885	COG1285	pathogenesis
KNP414_RS28890	COG0077	Prephenate dehydratase
KNP414_RS28895	COG0083	homoserine kinase activity
KNP414_RS28900	COG0460	homoserine dehydrogenase
KNP414_RS28905	COG4492	Belongs to the UPF0735 family
KNP414_RS28910	COG1051	belongs to the nudix hydrolase family
KNP414_RS28915	COG1119	ATPase activity
KNP414_RS28920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KNP414_RS28925	COG0243	molybdopterin cofactor binding
KNP414_RS28930	COG2223	nitrite transmembrane transporter activity
KNP414_RS28935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KNP414_RS28945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KNP414_RS28950	COG2868	ribosomal protein
KNP414_RS28955	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KNP414_RS28965	COG1994	Peptidase M50
KNP414_RS28975	COG0772	Belongs to the SEDS family
KNP414_RS28980	COG2894	cell division
KNP414_RS28985	COG0850	regulation of cytokinetic process
KNP414_RS29000	COG1077	Cell shape determining protein MreB Mrl
KNP414_RS29005	COG2003	Belongs to the UPF0758 family
KNP414_RS29010	COG0424	maF-like protein
KNP414_RS29030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KNP414_RS29035	COG0285	dihydrofolate synthase activity
KNP414_RS29040	COG0525	valine-tRNA ligase activity
KNP414_RS29045	COG1388	LysM domain
KNP414_RS29050	COG0564	pseudouridine synthase activity
KNP414_RS29055	COG5434	Belongs to the glycosyl hydrolase 28 family
KNP414_RS29055	COG4632	Exopolysaccharide biosynthesis protein
KNP414_RS29060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KNP414_RS29065	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KNP414_RS29070	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KNP414_RS29075	COG0113	porphobilinogen synthase activity
KNP414_RS29090	COG1648	precorrin-2 dehydrogenase activity
KNP414_RS29090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KNP414_RS29095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KNP414_RS29110	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KNP414_RS29120	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KNP414_RS29130	COG1067	ATP-dependent peptidase activity
KNP414_RS29130	COG0470	DNA polymerase III
KNP414_RS29135	COG0860	N-Acetylmuramoyl-L-alanine amidase
KNP414_RS29140	COG2861	carbohydrate metabolic process
KNP414_RS29150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KNP414_RS29155	COG0740	serine-type endopeptidase activity
KNP414_RS29160	COG0544	peptidyl-prolyl cis-trans isomerase activity
KNP414_RS29190	COG0367	asparagine synthase
KNP414_RS29195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KNP414_RS29200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KNP414_RS29205	COG5401	PFAM Sporulation and spore germination
KNP414_RS29215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KNP414_RS29230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNP414_RS29240	COG1940	carbohydrate kinase activity
KNP414_RS29255	COG4566	intracellular signal transduction
KNP414_RS29270	COG2270	Major facilitator Superfamily
KNP414_RS29285	COG0753	catalase activity
KNP414_RS29295	COG2197	response regulator
KNP414_RS29310	COG0475	glutathione-regulated potassium exporter activity
KNP414_RS29315	COG3963	phosphatidate phosphatase activity
KNP414_RS29320	COG1970	mechanosensitive ion channel activity
KNP414_RS29325	COG2340	Cysteine-rich secretory protein family
KNP414_RS29330	COG4549	nuclear export factor GLE1
KNP414_RS29335	COG2197	response regulator
KNP414_RS29340	COG4585	Histidine kinase
KNP414_RS29345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNP414_RS29395	COG0463	Glycosyl transferase, family 2
KNP414_RS29430	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KNP414_RS29435	COG1091	dTDP-4-dehydrorhamnose reductase activity
KNP414_RS29445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KNP414_RS29455	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS29460	COG0519	Catalyzes the synthesis of GMP from XMP
KNP414_RS29485	COG1846	Transcriptional regulator
KNP414_RS29495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KNP414_RS29500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KNP414_RS29510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KNP414_RS29515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNP414_RS29525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KNP414_RS29530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNP414_RS29535	COG1122	ATPase activity
KNP414_RS29550	COG0688	phosphatidylethanolamine metabolic process
KNP414_RS29555	COG2223	nitrite transmembrane transporter activity
KNP414_RS29560	COG2199	diguanylate cyclase activity
KNP414_RS29560	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KNP414_RS29570	COG0456	acetyltransferase
KNP414_RS29580	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS29580	COG4977	sequence-specific DNA binding
KNP414_RS29585	COG2066	Belongs to the glutaminase family
KNP414_RS29590	COG4214	carbohydrate transport
KNP414_RS29600	COG4213	ABC transporter substrate-binding protein
KNP414_RS29610	COG2207	Transcriptional regulator
KNP414_RS29610	COG4753	response regulator
KNP414_RS29615	COG2972	Histidine kinase
KNP414_RS29630	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KNP414_RS29635	COG1349	DNA-binding transcription factor activity
KNP414_RS29650	COG4221	oxidoreductase activity
KNP414_RS29675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KNP414_RS29690	COG1846	Transcriptional regulator
KNP414_RS29695	COG2814	Major facilitator Superfamily
KNP414_RS29730	COG3976	FMN-binding domain protein
KNP414_RS29730	COG1053	succinate dehydrogenase
KNP414_RS29735	COG0583	DNA-binding transcription factor activity
KNP414_RS29750	COG2258	MOSC domain
KNP414_RS29765	COG1506	peptidase
KNP414_RS29775	COG1595	DNA-templated transcription, initiation
KNP414_RS29785	COG0300	oxidoreductase activity
KNP414_RS29790	COG1406	Chemotaxis phosphatase CheX
KNP414_RS29795	COG2720	vancomycin resistance protein
KNP414_RS29815	COG1131	(ABC) transporter
KNP414_RS29835	COG3458	cephalosporin-C deacetylase activity
KNP414_RS29855	COG0647	UMP catabolic process
KNP414_RS29875	COG1201	RNA secondary structure unwinding
KNP414_RS29880	COG0789	Transcriptional regulator
KNP414_RS29885	COG0477	Major facilitator Superfamily
KNP414_RS29895	COG2814	Major facilitator Superfamily
KNP414_RS29900	COG0583	DNA-binding transcription factor activity
KNP414_RS29905	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KNP414_RS29910	COG2755	lipolytic protein G-D-S-L family
KNP414_RS29920	COG1472	Belongs to the glycosyl hydrolase 3 family
KNP414_RS29925	COG4753	response regulator
KNP414_RS29925	COG2207	Transcriptional regulator
KNP414_RS29930	COG2972	Histidine kinase
KNP414_RS29935	COG0395	ABC-type sugar transport system, permease component
KNP414_RS29940	COG1175	transmembrane transport
KNP414_RS29945	COG1653	transport
KNP414_RS29950	COG1263	PTS System
KNP414_RS29950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNP414_RS29955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNP414_RS29955	COG2190	(PTS) system
KNP414_RS29955	COG1263	PTS System
KNP414_RS29960	COG3711	transcriptional antiterminator
KNP414_RS29970	COG1695	Transcriptional regulator
KNP414_RS30005	COG0840	transmembrane signaling receptor activity
KNP414_RS30010	COG0745	RESPONSE REGULATOR receiver
KNP414_RS30015	COG5002	protein histidine kinase activity
KNP414_RS30020	COG0534	Mate efflux family protein
KNP414_RS30030	COG0500	methyltransferase
KNP414_RS30035	COG5002	protein histidine kinase activity
KNP414_RS30045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KNP414_RS30055	COG2766	serine protein kinase
KNP414_RS30065	COG1966	Carbon starvation protein
KNP414_RS30070	COG3279	Response regulator of the LytR AlgR family
KNP414_RS30075	COG3275	phosphorelay sensor kinase activity
KNP414_RS30090	COG0726	polysaccharide deacetylase
KNP414_RS30095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNP414_RS30100	COG0477	Major facilitator Superfamily
KNP414_RS30120	COG2972	Histidine kinase
KNP414_RS30125	COG2197	response regulator
KNP414_RS30145	COG2002	toxin-antitoxin pair type II binding
KNP414_RS30150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KNP414_RS30155	COG0745	RESPONSE REGULATOR receiver
KNP414_RS30175	COG1396	sequence-specific DNA binding
KNP414_RS30180	COG1396	sequence-specific DNA binding
KNP414_RS30215	COG1696	Membrane protein involved in D-alanine export
KNP414_RS30225	COG5039	Polysaccharide pyruvyl transferase
KNP414_RS30240	COG0662	Cupin 2, conserved barrel domain protein
KNP414_RS30240	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KNP414_RS30245	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KNP414_RS30250	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS30270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KNP414_RS30275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KNP414_RS30280	COG3944	biosynthesis protein
KNP414_RS30290	COG0110	maltose O-acetyltransferase activity
KNP414_RS30295	COG0297	glycogen (starch) synthase activity
KNP414_RS30310	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS30325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KNP414_RS30330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KNP414_RS30335	COG0489	protein tyrosine kinase activity
KNP414_RS30345	COG4464	protein tyrosine phosphatase activity
KNP414_RS30355	COG1396	sequence-specific DNA binding
KNP414_RS30360	COG0174	glutamine synthetase
KNP414_RS30365	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KNP414_RS30375	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KNP414_RS30380	COG5002	protein histidine kinase activity
KNP414_RS30380	COG3850	Histidine kinase
KNP414_RS30385	COG0745	RESPONSE REGULATOR receiver
KNP414_RS30390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNP414_RS30400	COG0004	ammonium transporteR
KNP414_RS30410	COG3584	3D domain protein
KNP414_RS30415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNP414_RS30435	COG0438	transferase activity, transferring glycosyl groups
KNP414_RS30440	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KNP414_RS30445	COG2602	Beta-lactamase
KNP414_RS30450	COG0626	cystathionine gamma-synthase activity
KNP414_RS30455	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KNP414_RS30460	COG0598	Magnesium transport protein CorA
KNP414_RS30475	COG0129	dihydroxy-acid dehydratase activity
KNP414_RS30495	COG1607	acyl-coa hydrolase
KNP414_RS30500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNP414_RS30505	COG4977	sequence-specific DNA binding
KNP414_RS30510	COG0673	inositol 2-dehydrogenase activity
KNP414_RS30515	COG0673	inositol 2-dehydrogenase activity
KNP414_RS30520	COG0436	Aminotransferase
KNP414_RS30545	COG0564	pseudouridine synthase activity
KNP414_RS30550	COG2096	Adenosyltransferase
KNP414_RS30560	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KNP414_RS30565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KNP414_RS30575	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KNP414_RS30580	COG1120	ATPase activity
KNP414_RS30585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS30590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNP414_RS30605	COG0436	Aminotransferase
KNP414_RS30610	COG1522	sequence-specific DNA binding
KNP414_RS30620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KNP414_RS30625	COG0477	Major facilitator Superfamily
KNP414_RS30635	COG3766	membrane
KNP414_RS30640	COG1842	Phage shock protein A
KNP414_RS30645	COG1193	negative regulation of DNA recombination
KNP414_RS30665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNP414_RS30680	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KNP414_RS30685	COG0072	phenylalanine-tRNA ligase activity
KNP414_RS30685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNP414_RS30690	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KNP414_RS30695	COG3647	Membrane
KNP414_RS30705	COG1528	Iron-storage protein
KNP414_RS30720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KNP414_RS30725	COG5001	Diguanylate cyclase
KNP414_RS30755	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KNP414_RS30780	COG2315	Protein conserved in bacteria
KNP414_RS30815	COG0667	Aldo Keto reductase
KNP414_RS30825	COG2372	response to copper ion
KNP414_RS30825	COG1276	copper resistance
KNP414_RS30830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNP414_RS30835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNP414_RS30845	COG0745	RESPONSE REGULATOR receiver
KNP414_RS30865	COG0730	response to heat
KNP414_RS30870	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KNP414_RS30875	COG5566	PFAM Mor transcription activator
KNP414_RS30885	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KNP414_RS30900	COG0737	Belongs to the 5'-nucleotidase family
KNP414_RS30915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KNP414_RS30945	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KNP414_RS30950	COG1131	(ABC) transporter
KNP414_RS30955	COG1587	Uroporphyrinogen-III synthase
KNP414_RS30960	COG3584	3D domain protein
KNP414_RS30965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KNP414_RS30975	COG3290	protein histidine kinase activity
KNP414_RS30985	COG1301	dicarboxylic acid transport
KNP414_RS31000	COG0833	amino acid
KNP414_RS31025	COG1686	Belongs to the peptidase S11 family
KNP414_RS31030	COG0516	GMP reductase activity
KNP414_RS31030	COG0517	IMP dehydrogenase activity
KNP414_RS31050	COG1131	(ABC) transporter
KNP414_RS31055	COG4473	ABC transporter
KNP414_RS31065	COG3011	Protein conserved in bacteria
KNP414_RS31075	COG0596	Alpha beta hydrolase
KNP414_RS31075	COG2945	thiolester hydrolase activity
KNP414_RS31090	COG1129	ABC transporter
KNP414_RS31120	COG0765	amino acid transport
KNP414_RS31125	COG0765	amino acid transport
KNP414_RS31130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNP414_RS31140	COG2340	Cysteine-rich secretory protein family
KNP414_RS31150	COG4999	Histidine kinase
KNP414_RS31150	COG3850	Histidine kinase
KNP414_RS31150	COG3437	response regulator, receiver
KNP414_RS31150	COG2205	protein histidine kinase activity
KNP414_RS31165	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KNP414_RS31185	COG0673	inositol 2-dehydrogenase activity
KNP414_RS31190	COG0395	ABC-type sugar transport system, permease component
KNP414_RS31195	COG1175	transmembrane transport
KNP414_RS31200	COG1653	transport
KNP414_RS31210	COG2972	Histidine kinase
KNP414_RS31230	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
KNP414_RS31255	COG1649	PFAM Uncharacterised BCR, COG1649
KNP414_RS31255	COG0726	polysaccharide deacetylase
KNP414_RS31265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KNP414_RS31280	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KNP414_RS31295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNP414_RS31300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNP414_RS31315	COG0778	Nitroreductase
KNP414_RS31330	COG1876	peptidase activity
KNP414_RS31350	COG0840	transmembrane signaling receptor activity
KNP414_RS31355	COG4211	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS31375	COG2972	Histidine kinase
KNP414_RS31380	COG2207	Transcriptional regulator
KNP414_RS31420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KNP414_RS31460	COG0784	Response regulator, receiver
KNP414_RS31460	COG2198	Histidine kinase
KNP414_RS31460	COG2205	protein histidine kinase activity
KNP414_RS31465	COG0167	dihydroorotate dehydrogenase activity
KNP414_RS31495	COG0670	Belongs to the BI1 family
KNP414_RS31500	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
KNP414_RS31510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNP414_RS31515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS31520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS31525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNP414_RS31550	COG0003	Pfam Anion-transporting ATPase
KNP414_RS31565	COG1605	Chorismate mutase
KNP414_RS31565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KNP414_RS31580	COG0667	Aldo Keto reductase
KNP414_RS31600	COG1979	alcohol dehydrogenase
KNP414_RS31625	COG1881	PFAM PEBP family protein
KNP414_RS31635	COG3209	COG3209 Rhs family protein
KNP414_RS31665	COG3321	synthase
KNP414_RS31665	COG0604	alcohol dehydrogenase
KNP414_RS31665	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS31680	COG0693	protein deglycase activity
KNP414_RS31690	COG1082	Xylose isomerase domain protein TIM barrel
KNP414_RS31705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNP414_RS31740	COG0076	glutamate decarboxylase activity
KNP414_RS31755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNP414_RS31760	COG1131	(ABC) transporter
KNP414_RS31770	COG2188	Transcriptional regulator
KNP414_RS31780	COG2222	sugar isomerase
KNP414_RS31785	COG0531	amino acid
KNP414_RS31825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KNP414_RS31830	COG2115	Belongs to the xylose isomerase family
KNP414_RS31865	COG2972	Histidine kinase
KNP414_RS31870	COG0395	ABC-type sugar transport system, permease component
KNP414_RS31875	COG1175	transmembrane transport
KNP414_RS31890	COG0667	Aldo Keto reductase
KNP414_RS31910	COG0765	amino acid transport
KNP414_RS31920	COG2197	response regulator
KNP414_RS31940	COG1131	(ABC) transporter
KNP414_RS31960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KNP414_RS31965	COG1136	(ABC) transporter
KNP414_RS31970	COG0577	efflux transmembrane transporter activity
KNP414_RS31995	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
KNP414_RS32030	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KNP414_RS32045	COG5002	protein histidine kinase activity
KNP414_RS32045	COG2198	Histidine kinase
KNP414_RS32045	COG0784	Response regulator, receiver
KNP414_RS32085	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KNP414_RS32085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNP414_RS32115	COG0084	hydrolase, TatD family'
KNP414_RS32120	COG0457	Tetratricopeptide repeat
KNP414_RS32120	COG0463	Glycosyl transferase, family 2
KNP414_RS32125	COG0084	hydrolase, TatD family'
KNP414_RS32135	COG3541	Predicted nucleotidyltransferase
KNP414_RS32165	COG0459	protein refolding
KNP414_RS32170	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KNP414_RS32185	COG1177	transmembrane transport
KNP414_RS32190	COG1176	ABC-type spermidine putrescine transport system, permease component I
KNP414_RS32200	COG1132	(ABC) transporter
KNP414_RS32205	COG1132	(ABC) transporter
KNP414_RS32220	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNP414_RS32225	COG0154	amidase activity
KNP414_RS32235	COG2706	6-phosphogluconolactonase activity
KNP414_RS32255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KNP414_RS32265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KNP414_RS32270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KNP414_RS32280	COG4677	pectinesterase activity
KNP414_RS32295	COG0386	Belongs to the glutathione peroxidase family
KNP414_RS32310	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS32315	COG1129	ABC transporter
KNP414_RS32320	COG1129	ABC transporter
KNP414_RS32325	COG1349	DNA-binding transcription factor activity
KNP414_RS32355	COG3706	GGDEF domain
KNP414_RS32360	COG2514	catechol 2,3-dioxygenase activity
KNP414_RS32365	COG2259	Doxx family
KNP414_RS32375	COG2205	protein histidine kinase activity
KNP414_RS32395	COG4191	Histidine kinase
KNP414_RS32410	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KNP414_RS32420	COG1459	type II secretion system
KNP414_RS32430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KNP414_RS32460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KNP414_RS32465	COG1523	belongs to the glycosyl hydrolase 13 family
KNP414_RS32470	COG0753	catalase activity
KNP414_RS32480	COG2197	response regulator
KNP414_RS32485	COG4585	Histidine kinase
KNP414_RS32490	COG3239	Fatty acid desaturase
KNP414_RS32495	COG0824	Thioesterase
KNP414_RS32500	COG3940	Belongs to the glycosyl hydrolase 43 family
KNP414_RS32530	COG1309	transcriptional regulator
KNP414_RS32535	COG2814	Major facilitator Superfamily
KNP414_RS32585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNP414_RS32590	COG1597	lipid kinase activity
KNP414_RS32600	COG4496	protein, YerC YecD
KNP414_RS32610	COG1902	pentaerythritol trinitrate reductase activity
KNP414_RS32615	COG2205	protein histidine kinase activity
KNP414_RS32645	COG2207	Transcriptional regulator
KNP414_RS32655	COG1595	DNA-templated transcription, initiation
KNP414_RS32660	COG2261	transglycosylase associated protein
KNP414_RS32690	COG1191	sigma factor activity
KNP414_RS32700	COG1366	Belongs to the anti-sigma-factor antagonist family
KNP414_RS32710	COG0783	Belongs to the Dps family
KNP414_RS32715	COG1744	ABC transporter substrate-binding protein PnrA-like
KNP414_RS32720	COG3845	ABC transporter
KNP414_RS32725	COG4603	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS32730	COG1079	Belongs to the binding-protein-dependent transport system permease family
KNP414_RS32735	COG2172	sigma factor antagonist activity
KNP414_RS32760	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KNP414_RS32770	COG3437	response regulator, receiver
KNP414_RS32770	COG2205	protein histidine kinase activity
KNP414_RS32770	COG3850	Histidine kinase
KNP414_RS32770	COG4999	Histidine kinase
KNP414_RS32775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KNP414_RS32785	COG2208	phosphoserine phosphatase activity
KNP414_RS32800	COG1595	DNA-templated transcription, initiation
KNP414_RS32810	COG1470	cell adhesion involved in biofilm formation
KNP414_RS32820	COG3384	dioxygenase
KNP414_RS32830	COG2378	regulation of single-species biofilm formation
KNP414_RS32835	COG3118	belongs to the thioredoxin family
KNP414_RS32855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNP414_RS32860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS32865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS32875	COG1819	glycosyl
KNP414_RS32880	COG0151	Belongs to the GarS family
KNP414_RS32895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KNP414_RS32900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KNP414_RS32905	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KNP414_RS32910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNP414_RS32915	COG0047	phosphoribosylformylglycinamidine synthase activity
KNP414_RS32920	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNP414_RS32925	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KNP414_RS32930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KNP414_RS32935	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KNP414_RS32940	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KNP414_RS32950	COG3583	domain protein
KNP414_RS32950	COG3584	3D domain protein
KNP414_RS32995	COG0456	acetyltransferase
KNP414_RS33000	COG1214	PFAM Peptidase M22, glycoprotease
KNP414_RS33005	COG0802	atpase or kinase
KNP414_RS33010	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KNP414_RS33025	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KNP414_RS33045	COG1793	dna ligase
KNP414_RS33045	COG3285	dna ligase
KNP414_RS33050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNP414_RS33055	COG0697	spore germination
KNP414_RS33095	COG0546	phosphoglycolate phosphatase activity
KNP414_RS33115	COG4533	DNA binding
KNP414_RS33130	COG0493	'glutamate synthase
KNP414_RS33135	COG0067	glutamate synthase
KNP414_RS33135	COG0069	glutamate synthase activity
KNP414_RS33135	COG0070	glutamate synthase
KNP414_RS33140	COG5002	protein histidine kinase activity
KNP414_RS33145	COG1435	thymidine kinase activity
KNP414_RS33150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KNP414_RS33155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNP414_RS33170	COG1595	DNA-templated transcription, initiation
KNP414_RS33175	COG0737	Belongs to the 5'-nucleotidase family
KNP414_RS33185	COG1233	COG1233 Phytoene dehydrogenase and related
KNP414_RS33190	COG0693	protein deglycase activity
KNP414_RS33215	COG0366	Alpha amylase catalytic
KNP414_RS33220	COG1418	mRNA catabolic process
KNP414_RS33230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KNP414_RS33240	COG2201	protein-glutamate methylesterase activity
KNP414_RS33265	COG0509	glycine decarboxylation via glycine cleavage system
KNP414_RS33270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KNP414_RS33275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KNP414_RS33280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KNP414_RS33300	COG5634	Uncharacterized conserved protein (DUF2278)
KNP414_RS33315	COG1609	Transcriptional regulator
KNP414_RS33330	COG3858	chitin binding
KNP414_RS33335	COG0493	'glutamate synthase
KNP414_RS33335	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
KNP414_RS33340	COG1968	undecaprenyl-diphosphatase activity
KNP414_RS33345	COG0598	Magnesium transport protein CorA
KNP414_RS33350	COG1376	ErfK ybiS ycfS ynhG family protein
KNP414_RS33355	COG1309	transcriptional regulator
KNP414_RS33360	COG3326	Membrane
KNP414_RS33375	COG1295	ribonuclease BN
KNP414_RS33385	COG5002	protein histidine kinase activity
KNP414_RS33410	COG1609	Transcriptional regulator
KNP414_RS33410	COG2207	Transcriptional regulator
KNP414_RS33420	COG0395	ABC-type sugar transport system, permease component
KNP414_RS33425	COG4209	transmembrane transport
KNP414_RS33440	COG1012	belongs to the aldehyde dehydrogenase family
KNP414_RS33445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KNP414_RS33455	COG1012	belongs to the aldehyde dehydrogenase family
KNP414_RS33460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KNP414_RS33465	COG1027	Aspartate ammonia-lyase
KNP414_RS33470	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KNP414_RS33475	COG2707	UPF0756 membrane protein
KNP414_RS33480	COG4191	Histidine kinase
KNP414_RS33500	COG3829	transcription factor binding
KNP414_RS33515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNP414_RS33520	COG0531	amino acid
KNP414_RS33530	COG2235	arginine
KNP414_RS33560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNP414_RS33570	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KNP414_RS33575	COG5662	AntiSigma factor
KNP414_RS33580	COG1595	DNA-templated transcription, initiation
KNP414_RS33585	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KNP414_RS33590	COG5002	protein histidine kinase activity
KNP414_RS33590	COG2205	protein histidine kinase activity
KNP414_RS33590	COG0784	Response regulator, receiver
KNP414_RS33605	COG0628	permease
KNP414_RS33610	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS33670	COG0726	polysaccharide deacetylase
KNP414_RS33675	COG2194	sulfuric ester hydrolase activity
KNP414_RS33685	COG0489	protein tyrosine kinase activity
KNP414_RS33690	COG0860	N-Acetylmuramoyl-L-alanine amidase
KNP414_RS33695	COG2046	Belongs to the sulfate adenylyltransferase family
KNP414_RS33700	COG0175	sulfate reduction
KNP414_RS33705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KNP414_RS33710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KNP414_RS33715	COG0101	tRNA pseudouridine synthase activity
KNP414_RS33720	COG0203	ribosomal protein L17
KNP414_RS33725	COG0202	RNA polymerase activity
KNP414_RS33730	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KNP414_RS33735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KNP414_RS33740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KNP414_RS33745	COG2163	COG2163 Ribosomal protein L14E L6E L27E
KNP414_RS33750	COG0024	Methionine aminopeptidase
KNP414_RS33755	COG0563	adenylate kinase activity
KNP414_RS33760	COG0201	protein transport
KNP414_RS33765	COG0200	Binds to the 23S rRNA
KNP414_RS33770	COG1841	ribosomal large subunit assembly
KNP414_RS33775	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KNP414_RS33780	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KNP414_RS33785	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KNP414_RS33790	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KNP414_RS33795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KNP414_RS33800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KNP414_RS33805	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KNP414_RS33810	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KNP414_RS33815	COG0255	Belongs to the universal ribosomal protein uL29 family
KNP414_RS33820	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KNP414_RS33825	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KNP414_RS33830	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KNP414_RS33835	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KNP414_RS33840	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KNP414_RS33845	COG0089	rRNA binding
KNP414_RS33850	COG0088	Forms part of the polypeptide exit tunnel
KNP414_RS33855	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KNP414_RS33860	COG0051	transcription antitermination factor activity, RNA binding
KNP414_RS33865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KNP414_RS33870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KNP414_RS33875	COG0049	tRNA binding
KNP414_RS33880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KNP414_RS33885	COG1358	cellular component organization or biogenesis
KNP414_RS33890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNP414_RS33895	COG0085	RNA polymerase activity
KNP414_RS33900	COG2813	Specifically methylates the guanine in position
KNP414_RS33905	COG0222	ribosome binding
KNP414_RS33915	COG0081	regulation of translation
KNP414_RS33920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KNP414_RS33925	COG0250	Participates in transcription elongation, termination and antitermination
KNP414_RS33930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KNP414_RS33935	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KNP414_RS33945	COG3688	RNA-binding protein containing a PIN domain
KNP414_RS33950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNP414_RS33955	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KNP414_RS33960	COG0215	cysteine-tRNA ligase activity
KNP414_RS33965	COG1045	serine acetyltransferase
KNP414_RS33970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNP414_RS33980	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KNP414_RS33985	COG4956	integral membrane protein (PIN domain superfamily)
KNP414_RS33990	COG1183	phosphatidylcholine synthase activity
KNP414_RS33995	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KNP414_RS34000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KNP414_RS34005	COG0542	response to heat
KNP414_RS34010	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KNP414_RS34015	COG3880	PFAM UvrB UvrC protein
KNP414_RS34020	COG4463	regulation of RNA biosynthetic process
KNP414_RS34045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KNP414_RS34050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KNP414_RS34055	COG1396	sequence-specific DNA binding
KNP414_RS34060	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KNP414_RS34065	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KNP414_RS34070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KNP414_RS34075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KNP414_RS34080	COG0512	Glutamine amidotransferase of anthranilate synthase
KNP414_RS34085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KNP414_RS34090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KNP414_RS34095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KNP414_RS34100	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KNP414_RS34105	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KNP414_RS34110	COG0157	Belongs to the NadC ModD family
KNP414_RS34115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KNP414_RS34120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KNP414_RS34125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KNP414_RS34135	COG0037	tRNA processing
KNP414_RS34140	COG0515	serine threonine protein kinase
KNP414_RS34155	COG2208	phosphoserine phosphatase activity
KNP414_RS34165	COG1098	S1 RNA binding domain
KNP414_RS34185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KNP414_RS34195	COG3956	TIGRFAM MazG family protein
KNP414_RS34200	COG3956	TIGRFAM MazG family protein
KNP414_RS34205	COG2244	polysaccharide biosynthetic process
KNP414_RS34210	COG2002	toxin-antitoxin pair type II binding
KNP414_RS34220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KNP414_RS34235	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KNP414_RS34240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KNP414_RS34245	COG2088	sporulation resulting in formation of a cellular spore
KNP414_RS34250	COG0251	oxidation-reduction process
KNP414_RS34255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNP414_RS34270	COG4466	Protein conserved in bacteria
KNP414_RS34280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KNP414_RS34290	COG3583	domain protein
KNP414_RS34290	COG3584	3D domain protein
KNP414_RS34295	COG0084	hydrolase, TatD family'
KNP414_RS34300	COG1078	dGTPase activity
KNP414_RS34305	COG2002	toxin-antitoxin pair type II binding
KNP414_RS34310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KNP414_RS34315	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KNP414_RS34320	COG4467	Involved in initiation control of chromosome replication
KNP414_RS34325	COG1774	PSP1 C-terminal conserved region
KNP414_RS34330	COG0470	DNA polymerase III
KNP414_RS34335	COG1728	Protein conserved in bacteria
KNP414_RS34340	COG3870	Protein conserved in bacteria
KNP414_RS34345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KNP414_RS34350	COG1982	Orn Lys Arg decarboxylase major
KNP414_RS34390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KNP414_RS34395	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KNP414_RS34400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNP414_RS34405	COG3852	Histidine kinase
KNP414_RS34415	COG0254	rRNA binding
KNP414_RS34425	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KNP414_RS34430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNP414_RS34435	COG0191	fructose-bisphosphate aldolase activity
KNP414_RS34445	COG0504	CTP synthase activity
KNP414_RS34450	COG3343	RNA polymerase activity
KNP414_RS34460	COG1404	Belongs to the peptidase S8 family
KNP414_RS34470	COG2207	Transcriptional regulator
KNP414_RS34470	COG1917	Cupin 2, conserved barrel domain protein
KNP414_RS34475	COG1408	metallophosphoesterase
KNP414_RS34495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNP414_RS34505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KNP414_RS34530	COG0415	Belongs to the DNA photolyase family
KNP414_RS34540	COG2329	Antibiotic biosynthesis monooxygenase
KNP414_RS34560	COG2154	pterin-4-alpha-carbinolamine dehydratase
KNP414_RS34575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNP414_RS34580	COG5002	protein histidine kinase activity
KNP414_RS34600	COG2308	Evidence 4 Homologs of previously reported genes of
KNP414_RS34610	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KNP414_RS34615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KNP414_RS34620	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KNP414_RS34630	COG5002	protein histidine kinase activity
KNP414_RS34640	COG1187	pseudouridine synthase activity
KNP414_RS34645	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KNP414_RS34655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNP414_RS34660	COG0477	Major facilitator Superfamily
KNP414_RS34670	COG2814	Major facilitator Superfamily
KNP414_RS34715	COG0772	Belongs to the SEDS family
KNP414_RS34730	COG0778	Nitroreductase
KNP414_RS34750	COG2814	Major facilitator Superfamily
KNP414_RS34760	COG1566	PFAM secretion protein HlyD family protein
KNP414_RS34765	COG1846	Transcriptional regulator
KNP414_RS34780	COG2133	pyrroloquinoline quinone binding
KNP414_RS34785	COG2233	PERMEase
KNP414_RS34790	COG0395	ABC-type sugar transport system, permease component
KNP414_RS34800	COG1653	transport
KNP414_RS34805	COG2207	Transcriptional regulator
KNP414_RS34805	COG4753	response regulator
KNP414_RS34815	COG3275	phosphorelay sensor kinase activity
KNP414_RS34820	COG0783	Belongs to the Dps family
KNP414_RS34825	COG4326	sporulation control protein
KNP414_RS34835	COG3386	PFAM SMP-30 Gluconolaconase
KNP414_RS34840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNP414_RS34850	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KNP414_RS34855	COG0187	DNA topoisomerase II activity
KNP414_RS34870	COG1396	sequence-specific DNA binding
KNP414_RS34875	COG2226	methyltransferase
KNP414_RS34890	COG2072	flavoprotein involved in K transport
KNP414_RS34905	COG1801	Protein of unknown function DUF72
KNP414_RS34910	COG0442	prolyl-tRNA aminoacylation
KNP414_RS34915	COG2217	Heavy metal translocating P-type atpase
KNP414_RS34935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNP414_RS34955	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNP414_RS34965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNP414_RS34975	COG1012	belongs to the aldehyde dehydrogenase family
KNP414_RS34980	COG0506	proline dehydrogenase activity
KNP414_RS35005	COG4585	Histidine kinase
KNP414_RS35030	COG0398	Pfam SNARE associated Golgi protein
KNP414_RS35050	COG1132	(ABC) transporter
KNP414_RS35075	COG1573	uracil-dna glycosylase
KNP414_RS35080	COG4191	Histidine kinase
KNP414_RS35100	COG1132	(ABC) transporter
KNP414_RS35105	COG1132	(ABC) transporter
KNP414_RS35115	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KNP414_RS35120	COG0783	Belongs to the Dps family
KNP414_RS35125	COG0735	belongs to the Fur family
KNP414_RS35135	COG0735	belongs to the Fur family
KNP414_RS35160	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KNP414_RS35165	COG0477	Major facilitator Superfamily
KNP414_RS35180	COG0395	ABC-type sugar transport system, permease component
KNP414_RS35185	COG4209	transmembrane transport
KNP414_RS35190	COG1653	transport
KNP414_RS35195	COG2207	Transcriptional regulator
KNP414_RS35205	COG5002	protein histidine kinase activity
KNP414_RS35210	COG0745	RESPONSE REGULATOR receiver
KNP414_RS35220	COG1120	ATPase activity
KNP414_RS35225	COG5001	Diguanylate cyclase
KNP414_RS35225	COG3300	MHYT domain
KNP414_RS35230	COG0840	transmembrane signaling receptor activity
KNP414_RS35255	COG1278	Cold shock
KNP414_RS35260	COG0840	transmembrane signaling receptor activity
KNP414_RS35265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KNP414_RS35270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KNP414_RS35275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KNP414_RS35280	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KNP414_RS35285	COG4607	ABC-type enterochelin transport system periplasmic component
KNP414_RS35290	COG4604	ABC transporter, ATP-binding protein
KNP414_RS35295	COG4605	iron ion homeostasis
KNP414_RS35300	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNP414_RS35305	COG1252	NADH dehydrogenase
KNP414_RS35320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNP414_RS35325	COG1653	transport
KNP414_RS35345	COG1028	Short-chain dehydrogenase reductase Sdr
KNP414_RS35355	COG0840	transmembrane signaling receptor activity
KNP414_RS35355	COG3290	protein histidine kinase activity
KNP414_RS35380	COG1131	(ABC) transporter
KNP414_RS35385	COG2755	lipolytic protein G-D-S-L family
KNP414_RS35395	COG0697	spore germination
KNP414_RS35410	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KNP414_RS35435	COG0640	Transcriptional regulator
KNP414_RS35440	COG3832	glyoxalase III activity
KNP414_RS35450	COG1959	2 iron, 2 sulfur cluster binding
KNP414_RS35455	COG2409	Drug exporters of the RND superfamily
KNP414_RS35475	COG0673	inositol 2-dehydrogenase activity
KNP414_RS35485	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KNP414_RS35490	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KNP414_RS35495	COG1733	regulation of RNA biosynthetic process
KNP414_RS35500	COG0300	oxidoreductase activity
KNP414_RS35505	COG0753	catalase activity
KNP414_RS35510	COG0561	phosphatase activity
KNP414_RS35525	COG1126	abc transporter atp-binding protein
KNP414_RS35530	COG0765	amino acid transport
KNP414_RS35535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNP414_RS35540	COG0398	Pfam SNARE associated Golgi protein
KNP414_RS35545	COG0398	Pfam SNARE associated Golgi protein
KNP414_RS35555	COG2966	Psort location CytoplasmicMembrane, score
KNP414_RS35560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KNP414_RS35565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNP414_RS35565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNP414_RS35595	COG1733	regulation of RNA biosynthetic process
KNP414_RS35600	COG2814	Major facilitator Superfamily
KNP414_RS35605	COG0656	L-ascorbic acid biosynthetic process
KNP414_RS35615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNP414_RS35620	COG3104	oligopeptide transport
KNP414_RS35625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KNP414_RS35630	COG2814	Major facilitator Superfamily
KNP414_RS35635	COG0322	excinuclease ABC activity
KNP414_RS35640	COG2824	Alkylphosphonate utilization operon protein PhnA
KNP414_RS35645	COG1309	transcriptional regulator
KNP414_RS35650	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KNP414_RS35660	COG3866	Pectate lyase
KNP414_RS35665	COG3708	Transcriptional regulator
KNP414_RS35670	COG2378	regulation of single-species biofilm formation
KNP414_RS35680	COG0513	Belongs to the DEAD box helicase family
KNP414_RS35685	COG2267	carboxylic ester hydrolase activity
KNP414_RS35705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNP414_RS35715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KNP414_RS35730	COG5002	protein histidine kinase activity
KNP414_RS35735	COG0745	RESPONSE REGULATOR receiver
KNP414_RS35740	COG0739	heme binding
KNP414_RS35740	COG0741	lytic transglycosylase activity
KNP414_RS35740	COG1196	nuclear chromosome segregation
KNP414_RS35755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KNP414_RS35760	COG0305	Participates in initiation and elongation during chromosome replication
KNP414_RS35770	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KNP414_RS35785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KNP414_RS35785	COG0517	IMP dehydrogenase activity
KNP414_RS35790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KNP414_RS35795	COG0629	single-stranded DNA binding
KNP414_RS35800	COG0360	Binds together with S18 to 16S ribosomal RNA
KNP414_RS35820	COG4481	Protein conserved in bacteria
KNP414_RS35825	COG0668	transmembrane transport
KNP414_RS35845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNP414_RS35850	COG1475	DNA binding
KNP414_RS35855	COG1192	Involved in chromosome partitioning
KNP414_RS35860	COG1475	DNA binding
KNP414_RS35865	COG0357	Ribosomal RNA small subunit methyltransferase G
KNP414_RS35870	COG0445	tRNA wobble uridine modification
KNP414_RS35875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KNP414_RS35880	COG1847	R3H domain protein
KNP414_RS35885	COG0706	membrane insertase activity
KNP414_RS35930	COG1216	Glycosyl transferase, family 2
KNP414_RS35935	COG1215	transferase activity, transferring glycosyl groups
KNP414_RS35965	COG2433	Pfam Transposase IS66
KNP414_RS35970	COG1396	sequence-specific DNA binding
KNP414_RS36085	COG1361	Conserved repeat domain