locus-tag	class	description
IAQ67_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAQ67_RS00010	COG0592	DNA-directed DNA polymerase activity
IAQ67_RS00015	COG2501	S4 domain
IAQ67_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IAQ67_RS00030	COG0187	DNA topoisomerase II activity
IAQ67_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAQ67_RS00045	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IAQ67_RS00080	COG1982	Orn Lys Arg decarboxylase major
IAQ67_RS00085	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAQ67_RS00090	COG3870	Protein conserved in bacteria
IAQ67_RS00095	COG1728	Protein conserved in bacteria
IAQ67_RS00100	COG0470	DNA polymerase III
IAQ67_RS00105	COG1774	PSP1 C-terminal conserved region
IAQ67_RS00110	COG4467	Involved in initiation control of chromosome replication
IAQ67_RS00115	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IAQ67_RS00120	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IAQ67_RS00125	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS00130	COG1078	dGTPase activity
IAQ67_RS00135	COG0084	hydrolase, TatD family'
IAQ67_RS00140	COG3583	domain protein
IAQ67_RS00140	COG3584	3D domain protein
IAQ67_RS00150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IAQ67_RS00160	COG4466	Protein conserved in bacteria
IAQ67_RS00170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IAQ67_RS00175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAQ67_RS00180	COG2088	sporulation resulting in formation of a cellular spore
IAQ67_RS00185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IAQ67_RS00190	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAQ67_RS00205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAQ67_RS00210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAQ67_RS00215	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS00220	COG2244	polysaccharide biosynthetic process
IAQ67_RS00225	COG3956	TIGRFAM MazG family protein
IAQ67_RS00235	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IAQ67_RS00255	COG1098	S1 RNA binding domain
IAQ67_RS00260	COG2208	phosphoserine phosphatase activity
IAQ67_RS00270	COG0515	serine threonine protein kinase
IAQ67_RS00285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAQ67_RS00290	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IAQ67_RS00295	COG0157	Belongs to the NadC ModD family
IAQ67_RS00300	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IAQ67_RS00310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAQ67_RS00315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAQ67_RS00320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IAQ67_RS00325	COG0512	Glutamine amidotransferase of anthranilate synthase
IAQ67_RS00330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAQ67_RS00335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IAQ67_RS00340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAQ67_RS00345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IAQ67_RS00350	COG1396	sequence-specific DNA binding
IAQ67_RS00355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAQ67_RS00360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAQ67_RS00370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAQ67_RS00385	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ67_RS00390	COG1012	belongs to the aldehyde dehydrogenase family
IAQ67_RS00395	COG0028	Belongs to the TPP enzyme family
IAQ67_RS00400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAQ67_RS00405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IAQ67_RS00435	COG0516	GMP reductase activity
IAQ67_RS00435	COG0517	IMP dehydrogenase activity
IAQ67_RS00440	COG1686	Belongs to the peptidase S11 family
IAQ67_RS00470	COG0583	DNA-binding transcription factor activity
IAQ67_RS00480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAQ67_RS00505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAQ67_RS00510	COG0590	tRNA wobble adenosine to inosine editing
IAQ67_RS00515	COG5002	protein histidine kinase activity
IAQ67_RS00520	COG1187	pseudouridine synthase activity
IAQ67_RS00525	COG1360	Flagellar Motor Protein
IAQ67_RS00530	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IAQ67_RS00540	COG2154	pterin-4-alpha-carbinolamine dehydratase
IAQ67_RS00550	COG0791	NLP P60 protein
IAQ67_RS00570	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAQ67_RS00575	COG1733	regulation of RNA biosynthetic process
IAQ67_RS00580	COG2190	(PTS) system
IAQ67_RS00585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ67_RS00600	COG1357	PFAM Pentapeptide repeats (8 copies)
IAQ67_RS00620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAQ67_RS00625	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IAQ67_RS00630	COG2211	Major facilitator Superfamily
IAQ67_RS00640	COG1694	Mazg nucleotide pyrophosphohydrolase
IAQ67_RS00645	COG1132	(ABC) transporter
IAQ67_RS00655	COG0583	DNA-binding transcription factor activity
IAQ67_RS00665	COG0018	arginyl-trna synthetase
IAQ67_RS00675	COG0583	DNA-binding transcription factor activity
IAQ67_RS00680	COG3842	ATPase activity
IAQ67_RS00690	COG1177	transmembrane transport
IAQ67_RS00695	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IAQ67_RS00700	COG1404	Belongs to the peptidase S8 family
IAQ67_RS00705	COG3343	RNA polymerase activity
IAQ67_RS00710	COG0504	CTP synthase activity
IAQ67_RS00715	COG2204	response regulator
IAQ67_RS00725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAQ67_RS00730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IAQ67_RS00740	COG0254	rRNA binding
IAQ67_RS00750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAQ67_RS00755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IAQ67_RS00760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAQ67_RS00840	COG2508	Transcriptional regulator
IAQ67_RS00845	COG3842	ATPase activity
IAQ67_RS00850	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IAQ67_RS00855	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IAQ67_RS00860	COG0546	phosphoglycolate phosphatase activity
IAQ67_RS00865	COG0110	maltose O-acetyltransferase activity
IAQ67_RS00875	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IAQ67_RS00880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IAQ67_RS00885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAQ67_RS00890	COG0131	Imidazoleglycerol-phosphate dehydratase
IAQ67_RS00895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAQ67_RS00900	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IAQ67_RS00905	COG0107	imidazoleglycerol-phosphate synthase activity
IAQ67_RS00910	COG0140	phosphoribosyl-ATP diphosphatase activity
IAQ67_RS00910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IAQ67_RS00915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IAQ67_RS00935	COG1940	carbohydrate kinase activity
IAQ67_RS00940	COG1660	Displays ATPase and GTPase activities
IAQ67_RS00945	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IAQ67_RS00950	COG1481	regulation of sporulation
IAQ67_RS00955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAQ67_RS00970	COG0740	serine-type endopeptidase activity
IAQ67_RS00990	COG0126	phosphoglycerate kinase activity
IAQ67_RS00995	COG0149	triose-phosphate isomerase activity
IAQ67_RS01005	COG0148	phosphopyruvate hydratase activity
IAQ67_RS01010	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAQ67_RS01015	COG0557	exoribonuclease II activity
IAQ67_RS01020	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IAQ67_RS01030	COG4224	UPF0291 protein
IAQ67_RS01035	COG2259	Doxx family
IAQ67_RS01040	COG0346	lactoylglutathione lyase activity
IAQ67_RS01045	COG1216	Glycosyl transferase, family 2
IAQ67_RS01050	COG2188	Transcriptional regulator
IAQ67_RS01055	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IAQ67_RS01065	COG1842	Phage shock protein A
IAQ67_RS01070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAQ67_RS01075	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IAQ67_RS01080	COG4260	virion core protein, lumpy skin disease virus
IAQ67_RS01095	COG2207	Transcriptional regulator
IAQ67_RS01095	COG1917	Cupin 2, conserved barrel domain protein
IAQ67_RS01110	COG0534	Mate efflux family protein
IAQ67_RS01115	COG0604	alcohol dehydrogenase
IAQ67_RS01135	COG4977	sequence-specific DNA binding
IAQ67_RS01135	COG1917	Cupin 2, conserved barrel domain protein
IAQ67_RS01150	COG1595	DNA-templated transcription, initiation
IAQ67_RS01160	COG3250	beta-galactosidase activity
IAQ67_RS01185	COG2972	Histidine kinase
IAQ67_RS01190	COG4753	response regulator
IAQ67_RS01190	COG2207	Transcriptional regulator
IAQ67_RS01195	COG0572	uridine kinase
IAQ67_RS01215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAQ67_RS01220	COG4715	Zinc finger, swim domain protein
IAQ67_RS01225	COG0531	amino acid
IAQ67_RS01235	COG0697	spore germination
IAQ67_RS01240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAQ67_RS01245	COG1554	hydrolase, family 65, central catalytic
IAQ67_RS01250	COG1609	Transcriptional regulator
IAQ67_RS01255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS01255	COG2190	(PTS) system
IAQ67_RS01255	COG1263	PTS System
IAQ67_RS01275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAQ67_RS01280	COG1846	Transcriptional regulator
IAQ67_RS01285	COG0784	Response regulator, receiver
IAQ67_RS01290	COG4191	Histidine kinase
IAQ67_RS01315	COG0601	transmembrane transport
IAQ67_RS01320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS01325	COG0444	Belongs to the ABC transporter superfamily
IAQ67_RS01330	COG4608	Belongs to the ABC transporter superfamily
IAQ67_RS01395	COG1653	transport
IAQ67_RS01400	COG1175	transmembrane transport
IAQ67_RS01405	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS01410	COG2207	Transcriptional regulator
IAQ67_RS01410	COG1917	Cupin 2, conserved barrel domain protein
IAQ67_RS01415	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS01420	COG3338	carbonate dehydratase activity
IAQ67_RS01430	COG1733	regulation of RNA biosynthetic process
IAQ67_RS01435	COG2814	Major facilitator Superfamily
IAQ67_RS01440	COG0656	L-ascorbic acid biosynthetic process
IAQ67_RS01445	COG1609	Transcriptional regulator
IAQ67_RS01450	COG1621	beta-fructofuranosidase activity
IAQ67_RS01475	COG0469	pyruvate kinase activity
IAQ67_RS01485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IAQ67_RS01500	COG0697	spore germination
IAQ67_RS01505	COG3152	Membrane
IAQ67_RS01510	COG3507	Belongs to the glycosyl hydrolase 43 family
IAQ67_RS01515	COG1278	Cold shock
IAQ67_RS01525	COG2267	carboxylic ester hydrolase activity
IAQ67_RS01545	COG1725	Transcriptional regulator
IAQ67_RS01550	COG1131	(ABC) transporter
IAQ67_RS01575	COG1609	Transcriptional regulator
IAQ67_RS01580	COG3459	Glycosyltransferase 36 associated
IAQ67_RS01590	COG1653	transport
IAQ67_RS01595	COG1175	transmembrane transport
IAQ67_RS01600	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS01610	COG0326	Molecular chaperone. Has ATPase activity
IAQ67_RS01620	COG0584	glycerophosphoryl diester phosphodiesterase
IAQ67_RS01630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAQ67_RS01640	COG0463	Glycosyl transferase, family 2
IAQ67_RS01645	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAQ67_RS01650	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS01655	COG5002	protein histidine kinase activity
IAQ67_RS01660	COG1404	Belongs to the peptidase S8 family
IAQ67_RS01665	COG1227	inorganic diphosphatase activity
IAQ67_RS01670	COG0657	acetylesterase activity
IAQ67_RS01675	COG1846	Transcriptional regulator
IAQ67_RS01680	COG1793	dna ligase
IAQ67_RS01690	COG2322	membrane
IAQ67_RS01705	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS01710	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IAQ67_RS01710	COG3291	Pkd domain containing protein
IAQ67_RS01720	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IAQ67_RS01725	COG1737	Transcriptional regulator
IAQ67_RS01730	COG1940	carbohydrate kinase activity
IAQ67_RS01735	COG1233	COG1233 Phytoene dehydrogenase and related
IAQ67_RS01765	COG4585	Histidine kinase
IAQ67_RS01770	COG2197	response regulator
IAQ67_RS01780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAQ67_RS01810	COG1175	transmembrane transport
IAQ67_RS01820	COG2972	Histidine kinase
IAQ67_RS01825	COG2207	Transcriptional regulator
IAQ67_RS01825	COG4753	response regulator
IAQ67_RS01830	COG0583	DNA-binding transcription factor activity
IAQ67_RS01835	COG0163	prenyltransferase activity
IAQ67_RS01840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IAQ67_RS01860	COG5492	domain, Protein
IAQ67_RS01860	COG4932	domain protein
IAQ67_RS01865	COG1760	l-serine dehydratase
IAQ67_RS01870	COG1760	l-serine dehydratase
IAQ67_RS01885	COG4608	Belongs to the ABC transporter superfamily
IAQ67_RS01890	COG0601	transmembrane transport
IAQ67_RS01910	COG0765	amino acid transport
IAQ67_RS01915	COG0765	amino acid transport
IAQ67_RS01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAQ67_RS01945	COG4932	domain protein
IAQ67_RS01945	COG1388	LysM domain
IAQ67_RS01955	COG2207	Transcriptional regulator
IAQ67_RS01955	COG1917	Cupin 2, conserved barrel domain protein
IAQ67_RS01960	COG2733	membrane
IAQ67_RS01965	COG2972	Histidine kinase
IAQ67_RS01965	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS01970	COG3279	Response regulator of the LytR AlgR family
IAQ67_RS01975	COG0778	Nitroreductase
IAQ67_RS01990	COG2373	Large extracellular alpha-helical protein
IAQ67_RS01995	COG4549	nuclear export factor GLE1
IAQ67_RS02000	COG2372	response to copper ion
IAQ67_RS02000	COG1276	copper resistance
IAQ67_RS02005	COG2199	diguanylate cyclase activity
IAQ67_RS02005	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IAQ67_RS02015	COG2814	Major facilitator Superfamily
IAQ67_RS02025	COG2608	mercury ion transmembrane transporter activity
IAQ67_RS02030	COG2217	Heavy metal translocating P-type atpase
IAQ67_RS02035	COG0778	Nitroreductase
IAQ67_RS02040	COG0084	hydrolase, TatD family'
IAQ67_RS02050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAQ67_RS02065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ67_RS02070	COG3871	stress protein (general stress protein 26)
IAQ67_RS02075	COG0737	Belongs to the 5'-nucleotidase family
IAQ67_RS02085	COG0604	alcohol dehydrogenase
IAQ67_RS02095	COG4221	oxidoreductase activity
IAQ67_RS02105	COG0366	Alpha amylase catalytic
IAQ67_RS02110	COG0560	Phosphoserine phosphatase
IAQ67_RS02120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAQ67_RS02125	COG2011	ABC-type metal ion transport system permease component
IAQ67_RS02130	COG0789	Transcriptional regulator
IAQ67_RS02155	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS02160	COG2205	protein histidine kinase activity
IAQ67_RS02190	COG0515	serine threonine protein kinase
IAQ67_RS02200	COG1070	Carbohydrate kinase
IAQ67_RS02215	COG0024	Methionine aminopeptidase
IAQ67_RS02225	COG4846	Membrane protein involved in cytochrome C biogenesis
IAQ67_RS02230	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IAQ67_RS02235	COG0778	Nitroreductase
IAQ67_RS02240	COG0392	lysyltransferase activity
IAQ67_RS02240	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAQ67_RS02255	COG2814	Major facilitator Superfamily
IAQ67_RS02260	COG2706	6-phosphogluconolactonase activity
IAQ67_RS02275	COG0456	acetyltransferase
IAQ67_RS02285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IAQ67_RS02285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IAQ67_RS02295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAQ67_RS02305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAQ67_RS02310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAQ67_RS02315	COG0011	TIGRFAM Protein of
IAQ67_RS02375	COG0662	Cupin 2, conserved barrel domain protein
IAQ67_RS02380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAQ67_RS02390	COG0412	Dienelactone hydrolase
IAQ67_RS02400	COG0640	Transcriptional regulator
IAQ67_RS02405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAQ67_RS02440	COG2770	Histidine kinase
IAQ67_RS02440	COG3437	response regulator, receiver
IAQ67_RS02445	COG0784	Response regulator, receiver
IAQ67_RS02445	COG2205	protein histidine kinase activity
IAQ67_RS02445	COG5002	protein histidine kinase activity
IAQ67_RS02450	COG0702	epimerase
IAQ67_RS02455	COG0251	oxidation-reduction process
IAQ67_RS02460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAQ67_RS02470	COG0385	Bile acid
IAQ67_RS02475	COG1902	pentaerythritol trinitrate reductase activity
IAQ67_RS02480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAQ67_RS02485	COG2207	Transcriptional regulator
IAQ67_RS02485	COG4753	response regulator
IAQ67_RS02490	COG2972	Histidine kinase
IAQ67_RS02520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAQ67_RS02530	COG1876	peptidase activity
IAQ67_RS02550	COG3766	membrane
IAQ67_RS02555	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS02565	COG2814	Major facilitator Superfamily
IAQ67_RS02570	COG1846	Transcriptional regulator
IAQ67_RS02575	COG1309	transcriptional regulator
IAQ67_RS02580	COG2814	Major facilitator Superfamily
IAQ67_RS02595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAQ67_RS02600	COG2357	RelA SpoT domain protein
IAQ67_RS02605	COG1854	S-ribosylhomocysteine lyase activity
IAQ67_RS02610	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS02615	COG1464	Belongs to the NlpA lipoprotein family
IAQ67_RS02620	COG2207	Transcriptional regulator
IAQ67_RS02630	COG2207	Transcriptional regulator
IAQ67_RS02635	COG0697	spore germination
IAQ67_RS02640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAQ67_RS02645	COG0210	DNA helicase
IAQ67_RS02675	COG1970	mechanosensitive ion channel activity
IAQ67_RS02680	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAQ67_RS02685	COG1595	DNA-templated transcription, initiation
IAQ67_RS02695	COG2258	MOSC domain
IAQ67_RS02710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAQ67_RS02720	COG0024	Methionine aminopeptidase
IAQ67_RS02755	COG1131	(ABC) transporter
IAQ67_RS02760	COG4152	abc transporter atp-binding protein
IAQ67_RS02765	COG1668	transmembrane transport
IAQ67_RS02775	COG0667	Aldo Keto reductase
IAQ67_RS02810	COG2315	Protein conserved in bacteria
IAQ67_RS02815	COG2030	dehydratase
IAQ67_RS02830	COG2267	carboxylic ester hydrolase activity
IAQ67_RS02850	COG0385	Bile acid
IAQ67_RS02875	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAQ67_RS02880	COG3250	beta-galactosidase activity
IAQ67_RS02885	COG1396	sequence-specific DNA binding
IAQ67_RS02895	COG0366	Alpha amylase catalytic
IAQ67_RS02900	COG1263	PTS System
IAQ67_RS02900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS02905	COG2188	Transcriptional regulator
IAQ67_RS02920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAQ67_RS02930	COG0531	amino acid
IAQ67_RS02935	COG0697	spore germination
IAQ67_RS02940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ67_RS02945	COG2146	nitrite reductase [NAD(P)H] activity
IAQ67_RS02955	COG3693	PFAM glycoside hydrolase, family 10
IAQ67_RS02965	COG0697	spore germination
IAQ67_RS02970	COG0531	amino acid
IAQ67_RS02980	COG1695	Transcriptional regulator
IAQ67_RS02985	COG3479	Phenolic acid decarboxylase
IAQ67_RS02990	COG1733	regulation of RNA biosynthetic process
IAQ67_RS03000	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS03005	COG5002	protein histidine kinase activity
IAQ67_RS03010	COG1183	phosphatidylcholine synthase activity
IAQ67_RS03015	COG0586	Pfam SNARE associated Golgi protein
IAQ67_RS03020	COG3223	Belongs to the PsiE family
IAQ67_RS03025	COG0628	permease
IAQ67_RS03035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAQ67_RS03040	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IAQ67_RS03050	COG2315	Protein conserved in bacteria
IAQ67_RS03055	COG0778	Nitroreductase
IAQ67_RS03060	COG0346	lactoylglutathione lyase activity
IAQ67_RS03070	COG3173	Aminoglycoside phosphotransferase
IAQ67_RS03095	COG2972	Histidine kinase
IAQ67_RS03100	COG2207	Transcriptional regulator
IAQ67_RS03100	COG4753	response regulator
IAQ67_RS03155	COG0789	Transcriptional regulator
IAQ67_RS03160	COG2814	Major facilitator Superfamily
IAQ67_RS03165	COG0589	response to stress
IAQ67_RS03170	COG1012	belongs to the aldehyde dehydrogenase family
IAQ67_RS03180	COG0574	Belongs to the PEP-utilizing enzyme family
IAQ67_RS03180	COG3848	Pyruvate phosphate dikinase
IAQ67_RS03190	COG2197	response regulator
IAQ67_RS03195	COG3850	Histidine kinase
IAQ67_RS03205	COG1309	transcriptional regulator
IAQ67_RS03215	COG2814	Major facilitator Superfamily
IAQ67_RS03240	COG2378	regulation of single-species biofilm formation
IAQ67_RS03245	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAQ67_RS03255	COG0697	spore germination
IAQ67_RS03260	COG1063	alcohol dehydrogenase
IAQ67_RS03265	COG2211	Major facilitator Superfamily
IAQ67_RS03270	COG0457	Tetratricopeptide repeat
IAQ67_RS03275	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS03280	COG0789	Transcriptional regulator
IAQ67_RS03295	COG1956	GAF domain-containing protein
IAQ67_RS03305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAQ67_RS03315	COG4721	ABC-type cobalt transport system, permease component
IAQ67_RS03320	COG1122	ATPase activity
IAQ67_RS03325	COG0477	Major facilitator Superfamily
IAQ67_RS03330	COG1621	beta-fructofuranosidase activity
IAQ67_RS03335	COG1621	beta-fructofuranosidase activity
IAQ67_RS03340	COG1846	Transcriptional regulator
IAQ67_RS03355	COG5577	PFAM Coat F domain
IAQ67_RS03360	COG1113	amino acid transport
IAQ67_RS03365	COG1280	lysine exporter protein (LysE YggA)
IAQ67_RS03370	COG2222	sugar isomerase
IAQ67_RS03375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAQ67_RS03380	COG2188	Transcriptional regulator
IAQ67_RS03385	COG1228	amidohydrolase
IAQ67_RS03390	COG1288	antiporter activity
IAQ67_RS03395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAQ67_RS03400	COG2081	HI0933 family
IAQ67_RS03405	COG5002	protein histidine kinase activity
IAQ67_RS03415	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IAQ67_RS03435	COG2207	Transcriptional regulator
IAQ67_RS03445	COG1263	PTS System
IAQ67_RS03445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS03450	COG2318	DinB family
IAQ67_RS03460	COG0456	acetyltransferase
IAQ67_RS03470	COG0328	RNA-DNA hybrid ribonuclease activity
IAQ67_RS03475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IAQ67_RS03485	COG0302	gtp cyclohydrolase
IAQ67_RS03490	COG0095	Lipoate-protein ligase
IAQ67_RS03495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAQ67_RS03505	COG1414	Transcriptional regulator
IAQ67_RS03510	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IAQ67_RS03520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAQ67_RS03535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IAQ67_RS03555	COG4294	response to UV
IAQ67_RS03560	COG0483	inositol monophosphate 1-phosphatase activity
IAQ67_RS03570	COG2972	Histidine kinase
IAQ67_RS03575	COG4753	response regulator
IAQ67_RS03575	COG2207	Transcriptional regulator
IAQ67_RS03580	COG1653	transport
IAQ67_RS03585	COG1175	transmembrane transport
IAQ67_RS03590	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS03595	COG2755	lipolytic protein G-D-S-L family
IAQ67_RS03600	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IAQ67_RS03610	COG0697	spore germination
IAQ67_RS03615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IAQ67_RS03620	COG1316	TRANSCRIPTIONal
IAQ67_RS03625	COG4555	ABC transporter
IAQ67_RS03640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IAQ67_RS03665	COG0697	spore germination
IAQ67_RS03680	COG0586	Pfam SNARE associated Golgi protein
IAQ67_RS03685	COG0519	Catalyzes the synthesis of GMP from XMP
IAQ67_RS03685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAQ67_RS03700	COG0583	DNA-binding transcription factor activity
IAQ67_RS03710	COG1846	Transcriptional regulator
IAQ67_RS03715	COG0604	alcohol dehydrogenase
IAQ67_RS03720	COG2252	PERMEase
IAQ67_RS03740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAQ67_RS03755	COG0252	asparaginase activity
IAQ67_RS03765	COG3326	Membrane
IAQ67_RS03770	COG0589	response to stress
IAQ67_RS03775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IAQ67_RS03780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAQ67_RS03785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAQ67_RS03790	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IAQ67_RS03795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAQ67_RS03800	COG0047	phosphoribosylformylglycinamidine synthase activity
IAQ67_RS03805	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAQ67_RS03810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IAQ67_RS03820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IAQ67_RS03825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAQ67_RS03835	COG0151	Belongs to the GarS family
IAQ67_RS03845	COG0789	Transcriptional regulator
IAQ67_RS03845	COG4978	Transcriptional regulator
IAQ67_RS03850	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS03855	COG1309	transcriptional regulator
IAQ67_RS03860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAQ67_RS03865	COG0765	amino acid transport
IAQ67_RS03870	COG1126	abc transporter atp-binding protein
IAQ67_RS03885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS03890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS03895	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IAQ67_RS03905	COG3290	protein histidine kinase activity
IAQ67_RS03910	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IAQ67_RS03915	COG0656	L-ascorbic acid biosynthetic process
IAQ67_RS03925	COG0640	Transcriptional regulator
IAQ67_RS03930	COG0400	carboxylic ester hydrolase activity
IAQ67_RS03945	COG1653	transport
IAQ67_RS03950	COG1175	transmembrane transport
IAQ67_RS03955	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS03960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAQ67_RS03965	COG3507	Belongs to the glycosyl hydrolase 43 family
IAQ67_RS03970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS03975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS04000	COG3384	dioxygenase
IAQ67_RS04010	COG1470	cell adhesion involved in biofilm formation
IAQ67_RS04015	COG1392	Phosphate transport regulator
IAQ67_RS04020	COG0306	phosphate transporter
IAQ67_RS04030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAQ67_RS04040	COG0598	Magnesium transport protein CorA
IAQ67_RS04050	COG4496	protein, YerC YecD
IAQ67_RS04060	COG1597	lipid kinase activity
IAQ67_RS04065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAQ67_RS04075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAQ67_RS04090	COG1228	amidohydrolase
IAQ67_RS04100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IAQ67_RS04105	COG5426	von Willebrand factor, type A
IAQ67_RS04125	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IAQ67_RS04155	COG0300	oxidoreductase activity
IAQ67_RS04170	COG1113	amino acid transport
IAQ67_RS04190	COG0778	Nitroreductase
IAQ67_RS04195	COG1733	regulation of RNA biosynthetic process
IAQ67_RS04200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAQ67_RS04220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAQ67_RS04225	COG3239	Fatty acid desaturase
IAQ67_RS04230	COG4585	Histidine kinase
IAQ67_RS04235	COG2197	response regulator
IAQ67_RS04240	COG1428	Deoxynucleoside kinase
IAQ67_RS04245	COG1428	Deoxynucleoside kinase
IAQ67_RS04250	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS04260	COG2011	ABC-type metal ion transport system permease component
IAQ67_RS04270	COG1473	amidohydrolase
IAQ67_RS04285	COG2814	Major facilitator Superfamily
IAQ67_RS04290	COG0583	DNA-binding transcription factor activity
IAQ67_RS04295	COG2814	Major facilitator Superfamily
IAQ67_RS04300	COG0710	3-dehydroquinate dehydratase activity
IAQ67_RS04305	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAQ67_RS04330	COG2814	Major facilitator Superfamily
IAQ67_RS04335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAQ67_RS04340	COG4989	oxidoreductase activity
IAQ67_RS04360	COG3541	Predicted nucleotidyltransferase
IAQ67_RS04370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAQ67_RS04385	COG1122	ATPase activity
IAQ67_RS04395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAQ67_RS04400	COG2011	ABC-type metal ion transport system permease component
IAQ67_RS04425	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS04430	COG1472	Belongs to the glycosyl hydrolase 3 family
IAQ67_RS04440	COG3266	domain, Protein
IAQ67_RS04440	COG1361	Conserved repeat domain
IAQ67_RS04440	COG2911	Protein conserved in bacteria
IAQ67_RS04450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAQ67_RS04455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS04460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS04465	COG1120	ATPase activity
IAQ67_RS04475	COG0189	ligase activity
IAQ67_RS04475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAQ67_RS04480	COG4264	IucA IucC family
IAQ67_RS04485	COG4264	IucA IucC family
IAQ67_RS04495	COG0019	diaminopimelate decarboxylase activity
IAQ67_RS04500	COG4264	IucA IucC family
IAQ67_RS04510	COG4474	Belongs to the UPF0398 family
IAQ67_RS04515	COG3401	FG-GAP repeat protein
IAQ67_RS04535	COG2116	formate transmembrane transporter activity
IAQ67_RS04540	COG0561	phosphatase activity
IAQ67_RS04570	COG2310	stress, protein
IAQ67_RS04575	COG2310	stress, protein
IAQ67_RS04580	COG2310	stress, protein
IAQ67_RS04590	COG0861	Integral membrane protein TerC family
IAQ67_RS04605	COG1358	cellular component organization or biogenesis
IAQ67_RS04635	COG2304	oxidoreductase activity
IAQ67_RS04645	COG4166	transmembrane transport
IAQ67_RS04650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS04655	COG0601	transmembrane transport
IAQ67_RS04660	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IAQ67_RS04665	COG0765	amino acid transport
IAQ67_RS04670	COG1126	abc transporter atp-binding protein
IAQ67_RS04680	COG1309	transcriptional regulator
IAQ67_RS04795	COG1902	pentaerythritol trinitrate reductase activity
IAQ67_RS04800	COG0789	Transcriptional regulator
IAQ67_RS04820	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS04835	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
IAQ67_RS04850	COG1733	regulation of RNA biosynthetic process
IAQ67_RS04875	COG1486	melibiose metabolic process
IAQ67_RS04880	COG2972	Histidine kinase
IAQ67_RS04885	COG2207	Transcriptional regulator
IAQ67_RS04895	COG1175	transmembrane transport
IAQ67_RS04900	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS04905	COG0006	proline dipeptidase activity
IAQ67_RS04920	COG3938	Belongs to the proline racemase family
IAQ67_RS04925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAQ67_RS04930	COG1012	belongs to the aldehyde dehydrogenase family
IAQ67_RS04970	COG3401	FG-GAP repeat protein
IAQ67_RS04995	COG1132	(ABC) transporter
IAQ67_RS05000	COG1132	(ABC) transporter
IAQ67_RS05010	COG2814	Major facilitator Superfamily
IAQ67_RS05025	COG2814	Major facilitator Superfamily
IAQ67_RS05030	COG2207	Transcriptional regulator
IAQ67_RS05030	COG4753	response regulator
IAQ67_RS05035	COG2972	Histidine kinase
IAQ67_RS05050	COG0561	phosphatase activity
IAQ67_RS05055	COG1486	melibiose metabolic process
IAQ67_RS05065	COG5297	Belongs to the glycosyl hydrolase family 6
IAQ67_RS05075	COG3437	response regulator, receiver
IAQ67_RS05075	COG4999	Histidine kinase
IAQ67_RS05075	COG3850	Histidine kinase
IAQ67_RS05075	COG2205	protein histidine kinase activity
IAQ67_RS05080	COG1725	Transcriptional regulator
IAQ67_RS05085	COG1131	(ABC) transporter
IAQ67_RS05110	COG0656	L-ascorbic acid biosynthetic process
IAQ67_RS05115	COG3663	DNA glycosylase
IAQ67_RS05120	COG0686	Belongs to the AlaDH PNT family
IAQ67_RS05155	COG1253	flavin adenine dinucleotide binding
IAQ67_RS05160	COG0840	transmembrane signaling receptor activity
IAQ67_RS05170	COG5522	Integral membrane protein (intg_mem_TP0381)
IAQ67_RS05175	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS05185	COG1285	pathogenesis
IAQ67_RS05190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAQ67_RS05210	COG0697	spore germination
IAQ67_RS05215	COG1378	Sugar-specific transcriptional regulator TrmB
IAQ67_RS05225	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IAQ67_RS05225	COG1605	Chorismate mutase
IAQ67_RS05230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAQ67_RS05230	COG3153	acetyltransferase
IAQ67_RS05235	COG0456	acetyltransferase
IAQ67_RS05260	COG2205	protein histidine kinase activity
IAQ67_RS05330	COG2972	Histidine kinase
IAQ67_RS05335	COG2197	response regulator
IAQ67_RS05340	COG1151	hydroxylamine reductase activity
IAQ67_RS05380	COG2319	Wd-40 repeat
IAQ67_RS05380	COG4249	Peptidase C14 caspase catalytic subunit p20
IAQ67_RS05395	COG4213	ABC transporter substrate-binding protein
IAQ67_RS05405	COG4214	carbohydrate transport
IAQ67_RS05410	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS05420	COG1522	sequence-specific DNA binding
IAQ67_RS05430	COG2217	Heavy metal translocating P-type atpase
IAQ67_RS05435	COG2223	nitrite transmembrane transporter activity
IAQ67_RS05460	COG1621	beta-fructofuranosidase activity
IAQ67_RS05465	COG4977	sequence-specific DNA binding
IAQ67_RS05465	COG1917	Cupin 2, conserved barrel domain protein
IAQ67_RS05470	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IAQ67_RS05480	COG0720	synthase
IAQ67_RS05485	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IAQ67_RS05520	COG0737	Belongs to the 5'-nucleotidase family
IAQ67_RS05530	COG1396	sequence-specific DNA binding
IAQ67_RS05570	COG2823	Periplasmic or secreted lipoprotein
IAQ67_RS05570	COG1652	LysM domain
IAQ67_RS05590	COG3299	homolog of phage Mu protein gp47
IAQ67_RS05615	COG4824	toxin secretion phage lysis holin
IAQ67_RS05620	COG3757	hydrolase, family 25
IAQ67_RS05635	COG0747	negative chemotaxis
IAQ67_RS05640	COG0601	transmembrane transport
IAQ67_RS05645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS05650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IAQ67_RS05655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ67_RS05670	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IAQ67_RS05675	COG3773	Cell wall hydrolase
IAQ67_RS05680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IAQ67_RS05685	COG0067	glutamate synthase
IAQ67_RS05685	COG0070	glutamate synthase
IAQ67_RS05685	COG0069	glutamate synthase activity
IAQ67_RS05695	COG2197	response regulator
IAQ67_RS05700	COG3944	biosynthesis protein
IAQ67_RS05705	COG0489	protein tyrosine kinase activity
IAQ67_RS05710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAQ67_RS05715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IAQ67_RS05720	COG1216	Glycosyl transferase, family 2
IAQ67_RS05730	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IAQ67_RS05750	COG0438	transferase activity, transferring glycosyl groups
IAQ67_RS05755	COG0438	transferase activity, transferring glycosyl groups
IAQ67_RS05765	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAQ67_RS05770	COG0662	Cupin 2, conserved barrel domain protein
IAQ67_RS05770	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IAQ67_RS05775	COG2133	pyrroloquinoline quinone binding
IAQ67_RS05775	COG5183	chlorophyll binding
IAQ67_RS05795	COG3944	biosynthesis protein
IAQ67_RS05800	COG0489	protein tyrosine kinase activity
IAQ67_RS05805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IAQ67_RS05810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAQ67_RS05840	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IAQ67_RS05845	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAQ67_RS05860	COG1131	(ABC) transporter
IAQ67_RS05865	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IAQ67_RS05870	COG0628	permease
IAQ67_RS05880	COG0739	heme binding
IAQ67_RS05885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAQ67_RS05890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAQ67_RS05900	COG3551	Protein conserved in bacteria
IAQ67_RS05905	COG0367	asparagine synthase
IAQ67_RS05935	COG1132	(ABC) transporter
IAQ67_RS05940	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IAQ67_RS05960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAQ67_RS05965	COG4689	acetoacetate decarboxylase
IAQ67_RS05970	COG0183	Belongs to the thiolase family
IAQ67_RS05980	COG0802	atpase or kinase
IAQ67_RS05985	COG1214	PFAM Peptidase M22, glycoprotease
IAQ67_RS05990	COG0456	acetyltransferase
IAQ67_RS05995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAQ67_RS06000	COG0488	(ABC) transporter
IAQ67_RS06005	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAQ67_RS06010	COG0315	cyclic pyranopterin monophosphate synthase activity
IAQ67_RS06015	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAQ67_RS06020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAQ67_RS06025	COG0805	protein transport
IAQ67_RS06030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IAQ67_RS06035	COG0459	protein refolding
IAQ67_RS06140	COG2814	Major facilitator Superfamily
IAQ67_RS06145	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IAQ67_RS06150	COG1522	sequence-specific DNA binding
IAQ67_RS06175	COG1175	transmembrane transport
IAQ67_RS06180	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS06185	COG1653	transport
IAQ67_RS06190	COG1309	transcriptional regulator
IAQ67_RS06205	COG2113	Glycine betaine
IAQ67_RS06210	COG0517	IMP dehydrogenase activity
IAQ67_RS06210	COG4175	Glycine betaine
IAQ67_RS06215	COG1510	regulation of RNA biosynthetic process
IAQ67_RS06220	COG2272	Belongs to the type-B carboxylesterase lipase family
IAQ67_RS06240	COG1131	(ABC) transporter
IAQ67_RS06245	COG2205	protein histidine kinase activity
IAQ67_RS06250	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS06265	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IAQ67_RS06270	COG0662	Cupin 2, conserved barrel domain protein
IAQ67_RS06270	COG2207	Transcriptional regulator
IAQ67_RS06285	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IAQ67_RS06290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAQ67_RS06295	COG0864	Transcriptional regulator
IAQ67_RS06300	COG2337	Toxic component of a toxin-antitoxin (TA) module
IAQ67_RS06305	COG2183	response to ionizing radiation
IAQ67_RS06330	COG0561	phosphatase activity
IAQ67_RS06335	COG1349	DNA-binding transcription factor activity
IAQ67_RS06375	COG0830	nickel cation binding
IAQ67_RS06385	COG0386	Belongs to the glutathione peroxidase family
IAQ67_RS06400	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IAQ67_RS06415	COG1914	H( )-stimulated, divalent metal cation uptake system
IAQ67_RS06425	COG1764	response to oxidative stress
IAQ67_RS06435	COG3011	Protein conserved in bacteria
IAQ67_RS06445	COG0803	Belongs to the bacterial solute-binding protein 9 family
IAQ67_RS06450	COG1121	(ABC) transporter
IAQ67_RS06455	COG1321	iron dependent repressor
IAQ67_RS06455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAQ67_RS06460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAQ67_RS06470	COG2205	protein histidine kinase activity
IAQ67_RS06515	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IAQ67_RS06525	COG1090	epimerase
IAQ67_RS06530	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IAQ67_RS06535	COG0788	formyltetrahydrofolate deformylase activity
IAQ67_RS06555	COG0166	Belongs to the GPI family
IAQ67_RS06560	COG1739	Uncharacterized protein family UPF0029
IAQ67_RS06570	COG0432	Pfam Uncharacterised protein family UPF0047
IAQ67_RS06575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IAQ67_RS06580	COG0321	lipoyl(octanoyl) transferase activity
IAQ67_RS06580	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IAQ67_RS06585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAQ67_RS06595	COG0561	phosphatase activity
IAQ67_RS06600	COG0095	Lipoate-protein ligase
IAQ67_RS06605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAQ67_RS06615	COG0588	phosphoglycerate mutase activity
IAQ67_RS06620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAQ67_RS06625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS06630	COG1120	ATPase activity
IAQ67_RS06635	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IAQ67_RS06640	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
IAQ67_RS06645	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IAQ67_RS06650	COG1492	cobalamin metabolic process
IAQ67_RS06655	COG0840	transmembrane signaling receptor activity
IAQ67_RS06660	COG2190	(PTS) system
IAQ67_RS06660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS06660	COG1263	PTS System
IAQ67_RS06665	COG3711	transcriptional antiterminator
IAQ67_RS06670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS06670	COG2190	(PTS) system
IAQ67_RS06670	COG1263	PTS System
IAQ67_RS06680	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IAQ67_RS06685	COG0006	proline dipeptidase activity
IAQ67_RS06695	COG1247	-acetyltransferase
IAQ67_RS06700	COG3610	response to peptide
IAQ67_RS06705	COG2966	Psort location CytoplasmicMembrane, score
IAQ67_RS06720	COG2112	serine threonine protein kinase
IAQ67_RS06730	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IAQ67_RS06745	COG0514	ATP-dependent DNA helicase (RecQ)
IAQ67_RS06755	COG1785	Belongs to the alkaline phosphatase family
IAQ67_RS06760	COG0586	Pfam SNARE associated Golgi protein
IAQ67_RS06780	COG3711	transcriptional antiterminator
IAQ67_RS06805	COG1051	belongs to the nudix hydrolase family
IAQ67_RS06805	COG1056	cytidyltransferase-related domain
IAQ67_RS06835	COG1418	mRNA catabolic process
IAQ67_RS06885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAQ67_RS06890	COG2205	protein histidine kinase activity
IAQ67_RS06895	COG2755	lipolytic protein G-D-S-L family
IAQ67_RS06910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAQ67_RS06945	COG2814	Major facilitator Superfamily
IAQ67_RS06950	COG0567	Dehydrogenase, E1 component
IAQ67_RS06955	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAQ67_RS06960	COG2318	DinB family
IAQ67_RS06970	COG1482	cell wall glycoprotein biosynthetic process
IAQ67_RS06975	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IAQ67_RS06980	COG1242	4 iron, 4 sulfur cluster binding
IAQ67_RS06990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IAQ67_RS06995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAQ67_RS07000	COG0671	phosphoesterase, PA-phosphatase related
IAQ67_RS07005	COG1215	transferase activity, transferring glycosyl groups
IAQ67_RS07015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IAQ67_RS07020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IAQ67_RS07025	COG1744	ABC transporter substrate-binding protein PnrA-like
IAQ67_RS07030	COG3845	ABC transporter
IAQ67_RS07035	COG4603	Belongs to the binding-protein-dependent transport system permease family
IAQ67_RS07040	COG1079	Belongs to the binding-protein-dependent transport system permease family
IAQ67_RS07055	COG0028	Belongs to the TPP enzyme family
IAQ67_RS07060	COG0440	acetolactate synthase activity
IAQ67_RS07065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IAQ67_RS07070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAQ67_RS07080	COG0450	alkyl hydroperoxide reductase
IAQ67_RS07090	COG4191	Histidine kinase
IAQ67_RS07110	COG0488	(ABC) transporter
IAQ67_RS07115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAQ67_RS07125	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IAQ67_RS07135	COG1193	negative regulation of DNA recombination
IAQ67_RS07140	COG3766	membrane
IAQ67_RS07150	COG0477	Major facilitator Superfamily
IAQ67_RS07170	COG1522	sequence-specific DNA binding
IAQ67_RS07175	COG0436	Aminotransferase
IAQ67_RS07190	COG2096	Adenosyltransferase
IAQ67_RS07195	COG0564	pseudouridine synthase activity
IAQ67_RS07200	COG1393	Belongs to the ArsC family
IAQ67_RS07205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAQ67_RS07210	COG1940	carbohydrate kinase activity
IAQ67_RS07220	COG0598	Magnesium transport protein CorA
IAQ67_RS07225	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IAQ67_RS07230	COG0626	cystathionine gamma-synthase activity
IAQ67_RS07235	COG0626	cystathionine gamma-synthase activity
IAQ67_RS07240	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IAQ67_RS07255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAQ67_RS07260	COG0475	glutathione-regulated potassium exporter activity
IAQ67_RS07265	COG0490	domain, Protein
IAQ67_RS07280	COG3584	3D domain protein
IAQ67_RS07290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAQ67_RS07295	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS07300	COG3850	Histidine kinase
IAQ67_RS07300	COG5002	protein histidine kinase activity
IAQ67_RS07305	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IAQ67_RS07310	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IAQ67_RS07315	COG0174	glutamine synthetase
IAQ67_RS07330	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS07345	COG2197	response regulator
IAQ67_RS07350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAQ67_RS07360	COG2766	serine protein kinase
IAQ67_RS07385	COG3212	peptidase
IAQ67_RS07395	COG5002	protein histidine kinase activity
IAQ67_RS07395	COG3850	Histidine kinase
IAQ67_RS07400	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS07405	COG4126	flavin adenine dinucleotide binding
IAQ67_RS07420	COG2508	Transcriptional regulator
IAQ67_RS07425	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS07430	COG5002	protein histidine kinase activity
IAQ67_RS07440	COG2719	SpoVR family
IAQ67_RS07445	COG2718	Belongs to the UPF0229 family
IAQ67_RS07450	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS07455	COG2205	protein histidine kinase activity
IAQ67_RS07515	COG1609	Transcriptional regulator
IAQ67_RS07520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IAQ67_RS07525	COG0561	phosphatase activity
IAQ67_RS07530	COG3933	PFAM sigma-54 factor interaction domain-containing protein
IAQ67_RS07530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IAQ67_RS07535	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS07535	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAQ67_RS07540	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS07540	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAQ67_RS07545	COG3715	PTS system
IAQ67_RS07550	COG3716	PTS system mannose fructose sorbose family IID component
IAQ67_RS07555	COG1621	beta-fructofuranosidase activity
IAQ67_RS07560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAQ67_RS07565	COG1609	Transcriptional regulator
IAQ67_RS07570	COG4209	transmembrane transport
IAQ67_RS07575	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS07585	COG1621	beta-fructofuranosidase activity
IAQ67_RS07590	COG1396	sequence-specific DNA binding
IAQ67_RS07595	COG1607	acyl-coa hydrolase
IAQ67_RS07610	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IAQ67_RS07620	COG1307	EDD domain protein, DegV family
IAQ67_RS07630	COG2363	Small membrane protein
IAQ67_RS07645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAQ67_RS07660	COG0640	Transcriptional regulator
IAQ67_RS07665	COG2814	Major facilitator Superfamily
IAQ67_RS07680	COG0456	acetyltransferase
IAQ67_RS07760	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IAQ67_RS07795	COG0300	oxidoreductase activity
IAQ67_RS07825	COG0582	viral genome integration into host DNA
IAQ67_RS07840	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IAQ67_RS07845	COG0783	Belongs to the Dps family
IAQ67_RS07850	COG0396	ATPase activity
IAQ67_RS07855	COG0719	Fe-S assembly protein
IAQ67_RS07860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAQ67_RS07865	COG0822	iron-sulfur transferase activity
IAQ67_RS07870	COG0719	Fe-S assembly protein
IAQ67_RS07880	COG3546	catalase activity
IAQ67_RS07895	COG0737	Belongs to the 5'-nucleotidase family
IAQ67_RS07905	COG0535	radical SAM domain protein
IAQ67_RS07910	COG1253	flavin adenine dinucleotide binding
IAQ67_RS07925	COG3546	catalase activity
IAQ67_RS07935	COG0463	Glycosyl transferase, family 2
IAQ67_RS07940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAQ67_RS07950	COG0546	phosphoglycolate phosphatase activity
IAQ67_RS07955	COG0189	ligase activity
IAQ67_RS07970	COG0189	ligase activity
IAQ67_RS07975	COG0189	ligase activity
IAQ67_RS07980	COG0189	ligase activity
IAQ67_RS07985	COG3679	Belongs to the UPF0342 family
IAQ67_RS07995	COG4109	DRTGG domain
IAQ67_RS08015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IAQ67_RS08025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IAQ67_RS08030	COG0825	malonyl-CoA metabolic process
IAQ67_RS08035	COG0469	pyruvate kinase activity
IAQ67_RS08040	COG0583	DNA-binding transcription factor activity
IAQ67_RS08045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAQ67_RS08050	COG0573	inorganic phosphate transmembrane transporter activity
IAQ67_RS08055	COG0581	inorganic phosphate transmembrane transporter activity
IAQ67_RS08060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAQ67_RS08070	COG0824	Thioesterase
IAQ67_RS08075	COG3030	protein affecting phage T7 exclusion by the F plasmid
IAQ67_RS08080	COG0628	permease
IAQ67_RS08085	COG0372	Belongs to the citrate synthase family
IAQ67_RS08090	COG0538	isocitrate dehydrogenase activity
IAQ67_RS08095	COG0039	L-malate dehydrogenase activity
IAQ67_RS08105	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS08110	COG5002	protein histidine kinase activity
IAQ67_RS08115	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS08120	COG0840	transmembrane signaling receptor activity
IAQ67_RS08125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAQ67_RS08130	COG0704	Plays a role in the regulation of phosphate uptake
IAQ67_RS08140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IAQ67_RS08145	COG1971	Probably functions as a manganese efflux pump
IAQ67_RS08150	COG0237	dephospho-CoA kinase activity
IAQ67_RS08165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IAQ67_RS08180	COG3254	rhamnose metabolic process
IAQ67_RS08185	COG2972	Histidine kinase
IAQ67_RS08190	COG4753	response regulator
IAQ67_RS08190	COG2207	Transcriptional regulator
IAQ67_RS08195	COG1653	transport
IAQ67_RS08200	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IAQ67_RS08205	COG2211	Major facilitator Superfamily
IAQ67_RS08215	COG5566	PFAM Mor transcription activator
IAQ67_RS08250	COG0840	transmembrane signaling receptor activity
IAQ67_RS08265	COG0583	DNA-binding transcription factor activity
IAQ67_RS08270	COG4122	O-methyltransferase activity
IAQ67_RS08275	COG1349	DNA-binding transcription factor activity
IAQ67_RS08280	COG1105	Belongs to the carbohydrate kinase PfkB family
IAQ67_RS08285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAQ67_RS08285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAQ67_RS08285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAQ67_RS08290	COG0583	DNA-binding transcription factor activity
IAQ67_RS08295	COG1942	4-Oxalocrotonate Tautomerase
IAQ67_RS08300	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAQ67_RS08305	COG3711	transcriptional antiterminator
IAQ67_RS08310	COG2190	(PTS) system
IAQ67_RS08310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS08310	COG1263	PTS System
IAQ67_RS08315	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS08320	COG0583	DNA-binding transcription factor activity
IAQ67_RS08325	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IAQ67_RS08335	COG2350	Protein conserved in bacteria
IAQ67_RS08345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAQ67_RS08385	COG0326	Molecular chaperone. Has ATPase activity
IAQ67_RS08430	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAQ67_RS08435	COG1733	regulation of RNA biosynthetic process
IAQ67_RS08440	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IAQ67_RS08450	COG0371	Dehydrogenase
IAQ67_RS08465	COG1069	ribulokinase activity
IAQ67_RS08485	COG1309	transcriptional regulator
IAQ67_RS08490	COG0300	oxidoreductase activity
IAQ67_RS08500	COG1902	pentaerythritol trinitrate reductase activity
IAQ67_RS08505	COG0604	alcohol dehydrogenase
IAQ67_RS08510	COG1063	alcohol dehydrogenase
IAQ67_RS08515	COG1309	transcriptional regulator
IAQ67_RS08520	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS08535	COG2801	Transposase and inactivated derivatives
IAQ67_RS08545	COG0726	polysaccharide deacetylase
IAQ67_RS08550	COG4824	toxin secretion phage lysis holin
IAQ67_RS08560	COG2445	Protein of unknown function DUF86
IAQ67_RS08570	COG4980	gas vesicle protein
IAQ67_RS08575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IAQ67_RS08595	COG4844	belongs to the
IAQ67_RS08605	COG1368	sulfuric ester hydrolase activity
IAQ67_RS08610	COG0116	Belongs to the methyltransferase superfamily
IAQ67_RS08615	COG4122	O-methyltransferase activity
IAQ67_RS08620	COG2814	Major facilitator Superfamily
IAQ67_RS08625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IAQ67_RS08630	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IAQ67_RS08635	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IAQ67_RS08640	COG2843	Capsule synthesis protein
IAQ67_RS08645	COG0584	glycerophosphoryl diester phosphodiesterase
IAQ67_RS08660	COG1309	transcriptional regulator
IAQ67_RS08665	COG0488	(ABC) transporter
IAQ67_RS08670	COG0667	Aldo Keto reductase
IAQ67_RS08675	COG0583	DNA-binding transcription factor activity
IAQ67_RS08680	COG1363	Peptidase, m42
IAQ67_RS08685	COG5416	Lipopolysaccharide assembly protein A domain
IAQ67_RS08690	COG1164	Oligoendopeptidase f
IAQ67_RS08705	COG0534	Mate efflux family protein
IAQ67_RS08725	COG0534	Mate efflux family protein
IAQ67_RS08740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAQ67_RS08745	COG0513	Belongs to the DEAD box helicase family
IAQ67_RS08750	COG5578	integral membrane protein
IAQ67_RS08765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IAQ67_RS08770	COG0705	Rhomboid family
IAQ67_RS08775	COG0583	DNA-binding transcription factor activity
IAQ67_RS08780	COG2738	Putative neutral zinc metallopeptidase
IAQ67_RS08785	COG0789	Transcriptional regulator
IAQ67_RS08790	COG0004	ammonium transporteR
IAQ67_RS08800	COG2176	DNA-directed DNA polymerase activity
IAQ67_RS08805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAQ67_RS08810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAQ67_RS08815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAQ67_RS08820	COG1141	Ferredoxin
IAQ67_RS08825	COG1376	ErfK ybiS ycfS ynhG family protein
IAQ67_RS08835	COG0167	dihydroorotate dehydrogenase activity
IAQ67_RS08840	COG2357	RelA SpoT domain protein
IAQ67_RS08845	COG1547	Domain of unknown function (DUF309)
IAQ67_RS08855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IAQ67_RS08855	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IAQ67_RS08860	COG1187	pseudouridine synthase activity
IAQ67_RS08865	COG5001	Diguanylate cyclase
IAQ67_RS08865	COG5002	protein histidine kinase activity
IAQ67_RS08865	COG3447	MASE1 domain protein
IAQ67_RS08875	COG3949	Membrane
IAQ67_RS08880	COG0586	Pfam SNARE associated Golgi protein
IAQ67_RS08885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAQ67_RS08900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAQ67_RS08915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAQ67_RS08920	COG2861	carbohydrate metabolic process
IAQ67_RS08950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAQ67_RS08960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAQ67_RS08965	COG0456	acetyltransferase
IAQ67_RS08970	COG2378	regulation of single-species biofilm formation
IAQ67_RS08980	COG2814	Major facilitator Superfamily
IAQ67_RS08985	COG1309	transcriptional regulator
IAQ67_RS09000	COG0456	acetyltransferase
IAQ67_RS09000	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAQ67_RS09005	COG0436	Aminotransferase
IAQ67_RS09035	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS09040	COG3507	Belongs to the glycosyl hydrolase 43 family
IAQ67_RS09045	COG3940	Belongs to the glycosyl hydrolase 43 family
IAQ67_RS09055	COG0702	epimerase
IAQ67_RS09060	COG2226	methyltransferase
IAQ67_RS09065	COG0456	acetyltransferase
IAQ67_RS09065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAQ67_RS09080	COG1846	Transcriptional regulator
IAQ67_RS09090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAQ67_RS09095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAQ67_RS09125	COG1609	Transcriptional regulator
IAQ67_RS09150	COG4895	conserved protein (DUF2196)
IAQ67_RS09155	COG3647	Membrane
IAQ67_RS09160	COG0438	transferase activity, transferring glycosyl groups
IAQ67_RS09170	COG4129	membrane
IAQ67_RS09175	COG3973	AAA domain
IAQ67_RS09180	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IAQ67_RS09185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAQ67_RS09205	COG0840	transmembrane signaling receptor activity
IAQ67_RS09210	COG2211	Major facilitator Superfamily
IAQ67_RS09215	COG1114	Component of the transport system for branched-chain amino acids
IAQ67_RS09220	COG1917	Cupin 2, conserved barrel domain protein
IAQ67_RS09220	COG2207	Transcriptional regulator
IAQ67_RS09225	COG1501	Belongs to the glycosyl hydrolase 31 family
IAQ67_RS09240	COG2814	Major facilitator Superfamily
IAQ67_RS09245	COG2814	Major facilitator Superfamily
IAQ67_RS09250	COG1846	Transcriptional regulator
IAQ67_RS09255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAQ67_RS09270	COG1649	PFAM Uncharacterised BCR, COG1649
IAQ67_RS09270	COG0726	polysaccharide deacetylase
IAQ67_RS09290	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IAQ67_RS09300	COG1846	Transcriptional regulator
IAQ67_RS09305	COG5012	cobalamin binding
IAQ67_RS09310	COG0784	Response regulator, receiver
IAQ67_RS09310	COG2198	Histidine kinase
IAQ67_RS09310	COG2205	protein histidine kinase activity
IAQ67_RS09315	COG2211	Major facilitator Superfamily
IAQ67_RS09330	COG2755	lipolytic protein G-D-S-L family
IAQ67_RS09335	COG1309	transcriptional regulator
IAQ67_RS09355	COG5646	InterPro IPR014922
IAQ67_RS09360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAQ67_RS09365	COG0791	NLP P60 protein
IAQ67_RS09370	COG1454	alcohol dehydrogenase
IAQ67_RS09385	COG1846	Transcriptional regulator
IAQ67_RS09390	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAQ67_RS09425	COG2207	Transcriptional regulator
IAQ67_RS09430	COG0531	amino acid
IAQ67_RS09455	COG0742	ribosomal rna small subunit methyltransferase
IAQ67_RS09460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IAQ67_RS09465	COG3314	Sporulation integral membrane protein YlbJ
IAQ67_RS09470	COG3480	Lon protease (S16) C-terminal proteolytic domain
IAQ67_RS09475	COG1323	Belongs to the UPF0348 family
IAQ67_RS09485	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IAQ67_RS09505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IAQ67_RS09515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAQ67_RS09520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAQ67_RS09525	COG0571	ribonuclease III activity
IAQ67_RS09530	COG1196	nuclear chromosome segregation
IAQ67_RS09535	COG0552	protein localization to endoplasmic reticulum
IAQ67_RS09540	COG1272	protein, Hemolysin III
IAQ67_RS09545	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IAQ67_RS09550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAQ67_RS09555	COG0228	four-way junction DNA binding
IAQ67_RS09565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IAQ67_RS09570	COG0336	Belongs to the RNA methyltransferase TrmD family
IAQ67_RS09575	COG0335	large ribosomal subunit rRNA binding
IAQ67_RS09590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAQ67_RS09605	COG0792	nuclease activity
IAQ67_RS09620	COG1764	response to oxidative stress
IAQ67_RS09625	COG1846	Transcriptional regulator
IAQ67_RS09630	COG0045	succinate-CoA ligase (ADP-forming) activity
IAQ67_RS09635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAQ67_RS09640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAQ67_RS09640	COG0758	DNA mediated transformation
IAQ67_RS09645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAQ67_RS09650	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IAQ67_RS09655	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IAQ67_RS09660	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IAQ67_RS09665	COG1815	bacterial-type flagellum-dependent cell motility
IAQ67_RS09670	COG1558	bacterial-type flagellum-dependent cell motility
IAQ67_RS09675	COG1677	Flagellar hook-basal body complex protein FliE
IAQ67_RS09680	COG1766	The M ring may be actively involved in energy transduction
IAQ67_RS09685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAQ67_RS09695	COG1157	protein secretion by the type III secretion system
IAQ67_RS09700	COG2882	bacterial-type flagellum organization
IAQ67_RS09715	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IAQ67_RS09725	COG4786	Flagellar basal body rod
IAQ67_RS09740	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAQ67_RS09745	COG1776	CheC inhibitor of MCP methylation
IAQ67_RS09745	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAQ67_RS09750	COG2201	protein-glutamate methylesterase activity
IAQ67_RS09755	COG3190	flagellar
IAQ67_RS09760	COG1338	Plays a role in the flagellum-specific transport system
IAQ67_RS09765	COG1987	bacterial-type flagellum assembly
IAQ67_RS09770	COG1684	flagellar biosynthetic protein fliR
IAQ67_RS09775	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAQ67_RS09780	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAQ67_RS09785	COG1419	protein localization to endoplasmic reticulum
IAQ67_RS09790	COG0455	bacterial-type flagellum organization
IAQ67_RS09795	COG2201	protein-glutamate methylesterase activity
IAQ67_RS09800	COG2198	Histidine kinase
IAQ67_RS09800	COG0643	Histidine kinase
IAQ67_RS09810	COG1776	CheC inhibitor of MCP methylation
IAQ67_RS09815	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
IAQ67_RS09825	COG1191	sigma factor activity
IAQ67_RS09850	COG0052	Belongs to the universal ribosomal protein uS2 family
IAQ67_RS09855	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IAQ67_RS09860	COG0528	UMP kinase activity
IAQ67_RS09865	COG0233	cytoplasmic translational termination
IAQ67_RS09870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAQ67_RS09875	COG4589	Belongs to the CDS family
IAQ67_RS09880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IAQ67_RS09885	COG0750	zinc metalloprotease
IAQ67_RS09890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAQ67_RS09895	COG2176	DNA-directed DNA polymerase activity
IAQ67_RS09900	COG0779	Required for maturation of 30S ribosomal subunits
IAQ67_RS09905	COG0195	Participates in both transcription termination and antitermination
IAQ67_RS09915	COG1358	cellular component organization or biogenesis
IAQ67_RS09925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IAQ67_RS09930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IAQ67_RS09935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAQ67_RS09940	COG0196	riboflavin kinase activity
IAQ67_RS09945	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IAQ67_RS09950	COG1185	polyribonucleotide nucleotidyltransferase activity
IAQ67_RS09955	COG0726	polysaccharide deacetylase
IAQ67_RS09960	COG0612	Peptidase, M16
IAQ67_RS09965	COG0756	dUTP diphosphatase activity
IAQ67_RS09970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAQ67_RS09975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAQ67_RS09980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IAQ67_RS09985	COG0527	aspartate kinase activity
IAQ67_RS09990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAQ67_RS09995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAQ67_RS10000	COG0740	serine-type endopeptidase activity
IAQ67_RS10010	COG1674	ftsk spoiiie
IAQ67_RS10020	COG0612	Peptidase, M16
IAQ67_RS10025	COG0612	Peptidase, M16
IAQ67_RS10030	COG0300	oxidoreductase activity
IAQ67_RS10045	COG1426	Protein conserved in bacteria
IAQ67_RS10060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAQ67_RS10065	COG1058	Belongs to the CinA family
IAQ67_RS10065	COG1546	Belongs to the CinA family
IAQ67_RS10085	COG1692	metallophosphoesterase
IAQ67_RS10090	COG2359	stage V sporulation protein S
IAQ67_RS10105	COG4869	propanediol catabolic process
IAQ67_RS10110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAQ67_RS10115	COG4550	Control of competence regulator ComK, YlbF/YmcA
IAQ67_RS10130	COG1335	isochorismatase
IAQ67_RS10135	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IAQ67_RS10140	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAQ67_RS10150	COG0018	arginyl-trna synthetase
IAQ67_RS10160	COG1132	(ABC) transporter
IAQ67_RS10165	COG1132	(ABC) transporter
IAQ67_RS10185	COG2707	UPF0756 membrane protein
IAQ67_RS10190	COG0492	ferredoxin-NADP+ reductase activity
IAQ67_RS10195	COG0640	Transcriptional regulator
IAQ67_RS10205	COG1376	ErfK ybiS ycfS ynhG family protein
IAQ67_RS10230	COG1674	ftsk spoiiie
IAQ67_RS10265	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS10270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAQ67_RS10280	COG0436	Aminotransferase
IAQ67_RS10290	COG1902	pentaerythritol trinitrate reductase activity
IAQ67_RS10290	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAQ67_RS10325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAQ67_RS10330	COG1643	Atp-dependent helicase
IAQ67_RS10345	COG0110	maltose O-acetyltransferase activity
IAQ67_RS10360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAQ67_RS10365	COG3599	regulation of cell shape
IAQ67_RS10370	COG1959	2 iron, 2 sulfur cluster binding
IAQ67_RS10395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ67_RS10405	COG1733	regulation of RNA biosynthetic process
IAQ67_RS10410	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IAQ67_RS10415	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IAQ67_RS10420	COG2135	peptidase activity
IAQ67_RS10425	COG0477	Major facilitator Superfamily
IAQ67_RS10430	COG1764	response to oxidative stress
IAQ67_RS10435	COG2706	6-phosphogluconolactonase activity
IAQ67_RS10455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IAQ67_RS10470	COG0534	Mate efflux family protein
IAQ67_RS10475	COG1404	Belongs to the peptidase S8 family
IAQ67_RS10485	COG3527	Alpha-acetolactate decarboxylase
IAQ67_RS10490	COG0028	Belongs to the TPP enzyme family
IAQ67_RS10495	COG1904	glucuronate isomerase
IAQ67_RS10500	COG2211	Major facilitator Superfamily
IAQ67_RS10505	COG1609	Transcriptional regulator
IAQ67_RS10510	COG0028	Belongs to the TPP enzyme family
IAQ67_RS10515	COG0246	Mannitol dehydrogenase
IAQ67_RS10520	COG2721	sulfolactate sulfo-lyase activity
IAQ67_RS10540	COG4209	transmembrane transport
IAQ67_RS10545	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS10560	COG2207	Transcriptional regulator
IAQ67_RS10560	COG4753	response regulator
IAQ67_RS10575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IAQ67_RS10580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IAQ67_RS10585	COG0058	SHG alpha-glucan phosphorylase activity
IAQ67_RS10605	COG0667	Aldo Keto reductase
IAQ67_RS10615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAQ67_RS10615	COG2111	Na H antiporter
IAQ67_RS10620	COG1006	Multisubunit Na H antiporter MnhC subunit
IAQ67_RS10625	COG0651	ATP synthesis coupled electron transport
IAQ67_RS10630	COG1863	multisubunit Na H antiporter MnhE subunit
IAQ67_RS10635	COG2212	antiporter activity
IAQ67_RS10640	COG1320	monovalent cation:proton antiporter activity
IAQ67_RS10650	COG0697	spore germination
IAQ67_RS10655	COG0523	cobalamin synthesis protein
IAQ67_RS10660	COG0583	DNA-binding transcription factor activity
IAQ67_RS10665	COG2329	Antibiotic biosynthesis monooxygenase
IAQ67_RS10675	COG2323	membrane
IAQ67_RS10680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IAQ67_RS10685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ67_RS10690	COG0431	NADPH-dependent FMN reductase
IAQ67_RS10695	COG0583	DNA-binding transcription factor activity
IAQ67_RS10700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAQ67_RS10705	COG0765	amino acid transport
IAQ67_RS10710	COG0765	amino acid transport
IAQ67_RS10715	COG1126	abc transporter atp-binding protein
IAQ67_RS10720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ67_RS10725	COG1473	amidohydrolase
IAQ67_RS10745	COG0747	negative chemotaxis
IAQ67_RS10750	COG0601	transmembrane transport
IAQ67_RS10755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS10760	COG0444	Belongs to the ABC transporter superfamily
IAQ67_RS10765	COG4608	Belongs to the ABC transporter superfamily
IAQ67_RS10770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAQ67_RS10795	COG1714	RDD family
IAQ67_RS10800	COG1199	ATP-dependent helicase activity
IAQ67_RS10815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAQ67_RS10820	COG0626	cystathionine gamma-synthase activity
IAQ67_RS10885	COG0477	Major facilitator Superfamily
IAQ67_RS10905	COG0254	rRNA binding
IAQ67_RS10910	COG0523	cobalamin synthesis protein
IAQ67_RS10920	COG0701	Predicted permease
IAQ67_RS10925	COG0523	cobalamin synthesis protein
IAQ67_RS10930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS10935	COG1120	ATPase activity
IAQ67_RS10940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAQ67_RS10945	COG1121	(ABC) transporter
IAQ67_RS10950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAQ67_RS10955	COG0803	Belongs to the bacterial solute-binding protein 9 family
IAQ67_RS10960	COG2201	protein-glutamate methylesterase activity
IAQ67_RS11010	COG3850	Histidine kinase
IAQ67_RS11010	COG5002	protein histidine kinase activity
IAQ67_RS11025	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IAQ67_RS11085	COG1215	transferase activity, transferring glycosyl groups
IAQ67_RS11090	COG1216	Glycosyl transferase, family 2
IAQ67_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS11105	COG3347	Dehydrogenase
IAQ67_RS11110	COG4952	isomerase
IAQ67_RS11115	COG1070	Carbohydrate kinase
IAQ67_RS11120	COG1349	DNA-binding transcription factor activity
IAQ67_RS11125	COG0247	lactate metabolic process
IAQ67_RS11130	COG1139	Iron-sulfur cluster binding protein
IAQ67_RS11140	COG1609	Transcriptional regulator
IAQ67_RS11145	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS11150	COG0697	spore germination
IAQ67_RS11155	COG3711	transcriptional antiterminator
IAQ67_RS11160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS11160	COG2190	(PTS) system
IAQ67_RS11160	COG1263	PTS System
IAQ67_RS11165	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS11190	COG3401	FG-GAP repeat protein
IAQ67_RS11190	COG2755	lipolytic protein G-D-S-L family
IAQ67_RS11215	COG1136	(ABC) transporter
IAQ67_RS11220	COG0577	efflux transmembrane transporter activity
IAQ67_RS11220	COG1136	(ABC) transporter
IAQ67_RS11225	COG0517	IMP dehydrogenase activity
IAQ67_RS11230	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IAQ67_RS11235	COG1494	fructose-1,6-bisphosphatase
IAQ67_RS11265	COG1132	(ABC) transporter
IAQ67_RS11270	COG1132	(ABC) transporter
IAQ67_RS11300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAQ67_RS11305	COG1827	regulation of RNA biosynthetic process
IAQ67_RS11310	COG1104	cysteine desulfurase activity
IAQ67_RS11315	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IAQ67_RS11335	COG0671	phosphoesterase, PA-phosphatase related
IAQ67_RS11345	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS11350	COG5002	protein histidine kinase activity
IAQ67_RS11350	COG3850	Histidine kinase
IAQ67_RS11355	COG0791	NLP P60 protein
IAQ67_RS11360	COG0438	transferase activity, transferring glycosyl groups
IAQ67_RS11380	COG0189	ligase activity
IAQ67_RS11395	COG1119	ATPase activity
IAQ67_RS11405	COG1054	Belongs to the UPF0176 family
IAQ67_RS11415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAQ67_RS11415	COG1522	sequence-specific DNA binding
IAQ67_RS11420	COG0442	prolyl-tRNA aminoacylation
IAQ67_RS11435	COG2140	Oxalate decarboxylase
IAQ67_RS11440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAQ67_RS11465	COG0346	lactoylglutathione lyase activity
IAQ67_RS11475	COG0622	Phosphoesterase
IAQ67_RS11485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAQ67_RS11515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS11520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS11535	COG1187	pseudouridine synthase activity
IAQ67_RS11545	COG1309	transcriptional regulator
IAQ67_RS11550	COG2814	Major facilitator Superfamily
IAQ67_RS11600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ67_RS11610	COG0740	serine-type endopeptidase activity
IAQ67_RS11620	COG2076	Multidrug Resistance protein
IAQ67_RS11625	COG2076	Multidrug Resistance protein
IAQ67_RS11630	COG1309	transcriptional regulator
IAQ67_RS11645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAQ67_RS11655	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS11665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAQ67_RS11670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAQ67_RS11680	COG2807	transmembrane transport
IAQ67_RS11695	COG0024	Methionine aminopeptidase
IAQ67_RS11705	COG5566	PFAM Mor transcription activator
IAQ67_RS11715	COG1331	Highly conserved protein containing a thioredoxin domain
IAQ67_RS11720	COG0840	transmembrane signaling receptor activity
IAQ67_RS11730	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS11740	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAQ67_RS11745	COG2199	diguanylate cyclase activity
IAQ67_RS11745	COG2203	Gaf domain
IAQ67_RS11750	COG3459	Glycosyltransferase 36 associated
IAQ67_RS11755	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IAQ67_RS11765	COG2363	Small membrane protein
IAQ67_RS11770	COG5297	Belongs to the glycosyl hydrolase family 6
IAQ67_RS11770	COG4447	cellulose binding
IAQ67_RS11775	COG1528	Iron-storage protein
IAQ67_RS11780	COG0456	acetyltransferase
IAQ67_RS11785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ67_RS11790	COG4946	Tricorn protease homolog
IAQ67_RS11790	COG1506	peptidase
IAQ67_RS11790	COG0823	Involved in the tonB-independent uptake of proteins
IAQ67_RS11795	COG4335	DNA alkylation repair
IAQ67_RS11800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAQ67_RS11830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAQ67_RS11830	COG0425	Belongs to the sulfur carrier protein TusA family
IAQ67_RS11835	COG2210	Belongs to the sulfur carrier protein TusA family
IAQ67_RS11840	COG1937	Protein conserved in bacteria
IAQ67_RS11845	COG2323	membrane
IAQ67_RS11850	COG0626	cystathionine gamma-synthase activity
IAQ67_RS11870	COG0596	Alpha beta hydrolase
IAQ67_RS11875	COG1011	Hydrolase
IAQ67_RS11890	COG1609	Transcriptional regulator
IAQ67_RS11905	COG0577	efflux transmembrane transporter activity
IAQ67_RS11915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAQ67_RS11920	COG1136	(ABC) transporter
IAQ67_RS11935	COG1595	DNA-templated transcription, initiation
IAQ67_RS11945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAQ67_RS11950	COG1063	alcohol dehydrogenase
IAQ67_RS11955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAQ67_RS11965	COG2207	Transcriptional regulator
IAQ67_RS11970	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS11985	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS11995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAQ67_RS12000	COG2226	methyltransferase
IAQ67_RS12035	COG0477	Major facilitator Superfamily
IAQ67_RS12040	COG0583	DNA-binding transcription factor activity
IAQ67_RS12065	COG1733	regulation of RNA biosynthetic process
IAQ67_RS12075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAQ67_RS12110	COG0697	spore germination
IAQ67_RS12130	COG1846	Transcriptional regulator
IAQ67_RS12150	COG0583	DNA-binding transcription factor activity
IAQ67_RS12160	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS12170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAQ67_RS12175	COG2364	Membrane
IAQ67_RS12180	COG1846	Transcriptional regulator
IAQ67_RS12185	COG0456	acetyltransferase
IAQ67_RS12190	COG2076	Multidrug Resistance protein
IAQ67_RS12195	COG2076	Multidrug Resistance protein
IAQ67_RS12200	COG2508	Transcriptional regulator
IAQ67_RS12215	COG0583	DNA-binding transcription factor activity
IAQ67_RS12220	COG0596	Alpha beta hydrolase
IAQ67_RS12225	COG3507	Belongs to the glycosyl hydrolase 43 family
IAQ67_RS12245	COG3414	Phosphotransferase system galactitol-specific IIB component
IAQ67_RS12250	COG3775	system Galactitol-specific IIC component
IAQ67_RS12255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAQ67_RS12260	COG1063	alcohol dehydrogenase
IAQ67_RS12295	COG3118	belongs to the thioredoxin family
IAQ67_RS12300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAQ67_RS12300	COG0425	Belongs to the sulfur carrier protein TusA family
IAQ67_RS12305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAQ67_RS12315	COG1609	Transcriptional regulator
IAQ67_RS12320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAQ67_RS12325	COG0492	ferredoxin-NADP+ reductase activity
IAQ67_RS12335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAQ67_RS12375	COG2972	Histidine kinase
IAQ67_RS12380	COG2207	Transcriptional regulator
IAQ67_RS12380	COG4753	response regulator
IAQ67_RS12385	COG4209	transmembrane transport
IAQ67_RS12390	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS12420	COG1874	Beta-galactosidase
IAQ67_RS12445	COG2153	protein acetylation
IAQ67_RS12450	COG1609	Transcriptional regulator
IAQ67_RS12530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAQ67_RS12675	COG4974	Belongs to the 'phage' integrase family
IAQ67_RS12680	COG0154	amidase activity
IAQ67_RS12685	COG0574	Belongs to the PEP-utilizing enzyme family
IAQ67_RS12685	COG3848	Pyruvate phosphate dikinase
IAQ67_RS12705	COG1312	Catalyzes the dehydration of D-mannonate
IAQ67_RS12710	COG0246	Mannitol dehydrogenase
IAQ67_RS12730	COG0667	Aldo Keto reductase
IAQ67_RS12735	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS12745	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS12750	COG1609	Transcriptional regulator
IAQ67_RS12755	COG0667	Aldo Keto reductase
IAQ67_RS12760	COG2207	Transcriptional regulator
IAQ67_RS12765	COG0667	Aldo Keto reductase
IAQ67_RS12770	COG4221	oxidoreductase activity
IAQ67_RS12775	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAQ67_RS12780	COG1309	transcriptional regulator
IAQ67_RS12790	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS12800	COG0640	Transcriptional regulator
IAQ67_RS12805	COG2814	Major facilitator Superfamily
IAQ67_RS12810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAQ67_RS12815	COG1131	(ABC) transporter
IAQ67_RS12840	COG0667	Aldo Keto reductase
IAQ67_RS12845	COG4733	cellulase activity
IAQ67_RS12845	COG5297	Belongs to the glycosyl hydrolase family 6
IAQ67_RS12850	COG2814	Major facilitator Superfamily
IAQ67_RS12860	COG1309	transcriptional regulator
IAQ67_RS12865	COG0477	Major facilitator Superfamily
IAQ67_RS12875	COG0601	transmembrane transport
IAQ67_RS12880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS12885	COG0444	Belongs to the ABC transporter superfamily
IAQ67_RS12895	COG0534	Mate efflux family protein
IAQ67_RS12900	COG0753	catalase activity
IAQ67_RS12905	COG0529	Catalyzes the synthesis of activated sulfate
IAQ67_RS12935	COG2066	Belongs to the glutaminase family
IAQ67_RS12940	COG2514	catechol 2,3-dioxygenase activity
IAQ67_RS12945	COG2259	Doxx family
IAQ67_RS12960	COG4632	Exopolysaccharide biosynthesis protein
IAQ67_RS12960	COG5434	Belongs to the glycosyl hydrolase 28 family
IAQ67_RS12975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAQ67_RS12980	COG2186	Transcriptional regulator
IAQ67_RS12985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS12990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS12995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAQ67_RS13005	COG2017	converts alpha-aldose to the beta-anomer
IAQ67_RS13010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ67_RS13020	COG2309	aminopeptidase activity
IAQ67_RS13030	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IAQ67_RS13035	COG1253	flavin adenine dinucleotide binding
IAQ67_RS13045	COG3773	Cell wall hydrolase
IAQ67_RS13050	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS13070	COG0531	amino acid
IAQ67_RS13075	COG0039	L-malate dehydrogenase activity
IAQ67_RS13100	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS13110	COG1193	negative regulation of DNA recombination
IAQ67_RS13115	COG1940	carbohydrate kinase activity
IAQ67_RS13125	COG4974	Belongs to the 'phage' integrase family
IAQ67_RS13150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS13155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS13160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAQ67_RS13165	COG1132	(ABC) transporter
IAQ67_RS13170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAQ67_RS13175	COG1879	ABC-type sugar transport system periplasmic component
IAQ67_RS13180	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAQ67_RS13185	COG1129	ABC transporter
IAQ67_RS13190	COG1869	D-ribose catabolic process
IAQ67_RS13195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAQ67_RS13200	COG1609	Transcriptional regulator
IAQ67_RS13205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IAQ67_RS13210	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS13230	COG1473	amidohydrolase
IAQ67_RS13240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS13245	COG0601	transmembrane transport
IAQ67_RS13250	COG0747	negative chemotaxis
IAQ67_RS13260	COG4974	Belongs to the 'phage' integrase family
IAQ67_RS13265	COG1763	Mo-molybdopterin cofactor biosynthetic process
IAQ67_RS13270	COG0303	'Molybdopterin
IAQ67_RS13305	COG1842	Phage shock protein A
IAQ67_RS13310	COG1902	pentaerythritol trinitrate reductase activity
IAQ67_RS13320	COG1388	LysM domain
IAQ67_RS13320	COG3584	3D domain protein
IAQ67_RS13325	COG1126	abc transporter atp-binding protein
IAQ67_RS13330	COG0765	amino acid transport
IAQ67_RS13335	COG1473	amidohydrolase
IAQ67_RS13345	COG0297	glycogen (starch) synthase activity
IAQ67_RS13350	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IAQ67_RS13355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IAQ67_RS13360	COG5002	protein histidine kinase activity
IAQ67_RS13365	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS13375	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IAQ67_RS13380	COG0477	Major facilitator Superfamily
IAQ67_RS13400	COG0493	'glutamate synthase
IAQ67_RS13405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAQ67_RS13410	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IAQ67_RS13425	COG0022	dehydrogenase e1 component
IAQ67_RS13440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAQ67_RS13445	COG1564	THIamine pyrophosphokinase
IAQ67_RS13450	COG0791	NLP P60 protein
IAQ67_RS13455	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS13460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAQ67_RS13465	COG2022	thiamine diphosphate biosynthetic process
IAQ67_RS13475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAQ67_RS13480	COG0352	thiamine-phosphate diphosphorylase activity
IAQ67_RS13485	COG0488	(ABC) transporter
IAQ67_RS13540	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IAQ67_RS13545	COG1119	ATPase activity
IAQ67_RS13550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAQ67_RS13560	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IAQ67_RS13565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IAQ67_RS13575	COG1234	tRNA 3'-trailer cleavage
IAQ67_RS13580	COG1410	methionine synthase
IAQ67_RS13580	COG0646	methionine synthase
IAQ67_RS13585	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IAQ67_RS13590	COG1011	Hydrolase
IAQ67_RS13600	COG4224	UPF0291 protein
IAQ67_RS13610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAQ67_RS13630	COG0456	acetyltransferase
IAQ67_RS13790	COG4824	toxin secretion phage lysis holin
IAQ67_RS13935	COG1783	phage Terminase large subunit
IAQ67_RS13940	COG5484	DNA packaging
IAQ67_RS13945	COG0582	viral genome integration into host DNA
IAQ67_RS14030	COG0592	DNA-directed DNA polymerase activity
IAQ67_RS14035	COG1484	DNA-dependent DNA replication
IAQ67_RS14070	COG1475	DNA binding
IAQ67_RS14085	COG1396	sequence-specific DNA binding
IAQ67_RS14090	COG4974	Belongs to the 'phage' integrase family
IAQ67_RS14095	COG0174	glutamine synthetase
IAQ67_RS14100	COG0789	Transcriptional regulator
IAQ67_RS14105	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IAQ67_RS14110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAQ67_RS14115	COG0464	growth
IAQ67_RS14120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IAQ67_RS14130	COG3331	DNA recombination
IAQ67_RS14140	COG0587	DNA-directed DNA polymerase activity
IAQ67_RS14160	COG1473	amidohydrolase
IAQ67_RS14175	COG0456	acetyltransferase
IAQ67_RS14180	COG1959	2 iron, 2 sulfur cluster binding
IAQ67_RS14275	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS14280	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS14335	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IAQ67_RS14340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAQ67_RS14360	COG0667	Aldo Keto reductase
IAQ67_RS14380	COG0667	Aldo Keto reductase
IAQ67_RS14400	COG0791	NLP P60 protein
IAQ67_RS14400	COG0741	lytic transglycosylase activity
IAQ67_RS14505	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAQ67_RS14510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAQ67_RS14530	COG0629	single-stranded DNA binding
IAQ67_RS14685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAQ67_RS14720	COG1595	DNA-templated transcription, initiation
IAQ67_RS14860	COG2310	stress, protein
IAQ67_RS14985	COG2199	diguanylate cyclase activity
IAQ67_RS14985	COG2203	Gaf domain
IAQ67_RS15000	COG2304	oxidoreductase activity
IAQ67_RS15025	COG2310	stress, protein
IAQ67_RS15035	COG2310	stress, protein
IAQ67_RS15040	COG0861	Integral membrane protein TerC family
IAQ67_RS15050	COG1358	cellular component organization or biogenesis
IAQ67_RS15070	COG1846	Transcriptional regulator
IAQ67_RS15070	COG0456	acetyltransferase
IAQ67_RS15075	COG2197	response regulator
IAQ67_RS15080	COG3850	Histidine kinase
IAQ67_RS15085	COG0577	efflux transmembrane transporter activity
IAQ67_RS15090	COG1136	(ABC) transporter
IAQ67_RS15110	COG1136	(ABC) transporter
IAQ67_RS15170	COG1674	ftsk spoiiie
IAQ67_RS15415	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAQ67_RS15470	COG2801	Transposase and inactivated derivatives
IAQ67_RS15485	COG3209	COG3209 Rhs family protein
IAQ67_RS15520	COG4974	Belongs to the 'phage' integrase family
IAQ67_RS15575	COG1595	DNA-templated transcription, initiation
IAQ67_RS15615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAQ67_RS15665	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS15690	COG2135	peptidase activity
IAQ67_RS15850	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IAQ67_RS15855	COG0756	dUTP diphosphatase activity
IAQ67_RS15860	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAQ67_RS15865	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAQ67_RS15870	COG1780	Probably involved in ribonucleotide reductase function
IAQ67_RS15880	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IAQ67_RS15880	COG1328	CTP reductase activity
IAQ67_RS15915	COG2226	methyltransferase
IAQ67_RS16320	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IAQ67_RS16335	COG2887	Belongs to the helicase family. UvrD subfamily
IAQ67_RS16505	COG3646	Phage regulatory protein
IAQ67_RS16615	COG0210	DNA helicase
IAQ67_RS16650	COG0776	regulation of translation
IAQ67_RS16735	COG1215	transferase activity, transferring glycosyl groups
IAQ67_RS16740	COG0438	transferase activity, transferring glycosyl groups
IAQ67_RS16760	COG0582	viral genome integration into host DNA
IAQ67_RS16770	COG1196	nuclear chromosome segregation
IAQ67_RS16770	COG0741	lytic transglycosylase activity
IAQ67_RS16770	COG0739	heme binding
IAQ67_RS16775	COG2433	Pfam Transposase IS66
IAQ67_RS16935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAQ67_RS16940	COG1923	regulation of RNA biosynthetic process
IAQ67_RS16945	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IAQ67_RS16950	COG2136	Putative SAM-dependent methyltransferase
IAQ67_RS16950	COG2521	methyltransferase
IAQ67_RS16955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IAQ67_RS16960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IAQ67_RS16975	COG0583	DNA-binding transcription factor activity
IAQ67_RS16980	COG0531	amino acid
IAQ67_RS16985	COG4129	membrane
IAQ67_RS16990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAQ67_RS16995	COG1116	anion transmembrane transporter activity
IAQ67_RS17000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ67_RS17005	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IAQ67_RS17010	COG0288	reversible hydration of carbon dioxide
IAQ67_RS17035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAQ67_RS17040	COG3119	arylsulfatase activity
IAQ67_RS17055	COG1566	PFAM secretion protein HlyD family protein
IAQ67_RS17060	COG2814	Major facilitator Superfamily
IAQ67_RS17065	COG1566	PFAM secretion protein HlyD family protein
IAQ67_RS17075	COG0716	FMN binding
IAQ67_RS17085	COG0564	pseudouridine synthase activity
IAQ67_RS17090	COG2814	Major facilitator Superfamily
IAQ67_RS17095	COG1846	Transcriptional regulator
IAQ67_RS17105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAQ67_RS17120	COG1131	(ABC) transporter
IAQ67_RS17135	COG2340	Cysteine-rich secretory protein family
IAQ67_RS17145	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IAQ67_RS17150	COG1132	(ABC) transporter
IAQ67_RS17155	COG1132	(ABC) transporter
IAQ67_RS17160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IAQ67_RS17175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAQ67_RS17185	COG2247	cell wall binding repeat
IAQ67_RS17185	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAQ67_RS17190	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAQ67_RS17195	COG0066	3-isopropylmalate dehydratase activity
IAQ67_RS17200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IAQ67_RS17225	COG2030	dehydratase
IAQ67_RS17235	COG3383	formate dehydrogenase (NAD+) activity
IAQ67_RS17240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAQ67_RS17250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAQ67_RS17250	COG0493	'glutamate synthase
IAQ67_RS17255	COG1027	Aspartate ammonia-lyase
IAQ67_RS17270	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IAQ67_RS17275	COG1785	Belongs to the alkaline phosphatase family
IAQ67_RS17280	COG0583	DNA-binding transcription factor activity
IAQ67_RS17305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAQ67_RS17310	COG0436	Aminotransferase
IAQ67_RS17315	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IAQ67_RS17320	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IAQ67_RS17330	COG1850	ribulose-bisphosphate carboxylase activity
IAQ67_RS17335	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IAQ67_RS17340	COG0235	Class ii aldolase
IAQ67_RS17345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAQ67_RS17370	COG3935	DnaD domain protein
IAQ67_RS17375	COG0017	Asparaginyl-tRNA synthetase
IAQ67_RS17380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAQ67_RS17385	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAQ67_RS17390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAQ67_RS17410	COG0402	S-adenosylhomocysteine deaminase activity
IAQ67_RS17415	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IAQ67_RS17420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAQ67_RS17420	COG1199	ATP-dependent helicase activity
IAQ67_RS17430	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IAQ67_RS17435	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IAQ67_RS17440	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IAQ67_RS17450	COG0617	tRNA 3'-terminal CCA addition
IAQ67_RS17455	COG0438	transferase activity, transferring glycosyl groups
IAQ67_RS17460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAQ67_RS17465	COG1803	Methylglyoxal synthase
IAQ67_RS17470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IAQ67_RS17480	COG1694	Mazg nucleotide pyrophosphohydrolase
IAQ67_RS17485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAQ67_RS17500	COG4347	Protein of unknown function (DUF1405)
IAQ67_RS17520	COG0588	phosphoglycerate mutase activity
IAQ67_RS17535	COG0287	Prephenate dehydrogenase
IAQ67_RS17540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAQ67_RS17545	COG0159	tryptophan synthase activity
IAQ67_RS17550	COG0133	tryptophan synthase activity
IAQ67_RS17555	COG0135	phosphoribosylanthranilate isomerase activity
IAQ67_RS17560	COG0134	indole-3-glycerol-phosphate synthase activity
IAQ67_RS17565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAQ67_RS17575	COG4401	Chorismate mutase type I
IAQ67_RS17580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IAQ67_RS17585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IAQ67_RS17590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IAQ67_RS17595	COG0105	UTP biosynthetic process
IAQ67_RS17605	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IAQ67_RS17610	COG0163	prenyltransferase activity
IAQ67_RS17615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IAQ67_RS17620	COG2226	methyltransferase
IAQ67_RS17645	COG0776	regulation of translation
IAQ67_RS17650	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAQ67_RS17655	COG1129	ABC transporter
IAQ67_RS17665	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IAQ67_RS17675	COG2871	sodium ion transport
IAQ67_RS17690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IAQ67_RS17695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IAQ67_RS17700	COG1160	GTP binding
IAQ67_RS17720	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IAQ67_RS17725	COG2959	enzyme of heme biosynthesis
IAQ67_RS17730	COG2339	peptidase activity
IAQ67_RS17735	COG4862	establishment of competence for transformation
IAQ67_RS17760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAQ67_RS17765	COG5002	protein histidine kinase activity
IAQ67_RS17770	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS17775	COG1187	pseudouridine synthase activity
IAQ67_RS17780	COG0700	Nucleoside recognition
IAQ67_RS17785	COG2715	membrane protein required for spore maturation
IAQ67_RS17790	COG1686	Belongs to the peptidase S11 family
IAQ67_RS17800	COG3874	Sporulation protein YtfJ
IAQ67_RS17810	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAQ67_RS17815	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAQ67_RS17825	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAQ67_RS17825	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAQ67_RS17840	COG0674	pyruvate-flavodoxin oxidoreductase activity
IAQ67_RS17850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAQ67_RS17855	COG0019	diaminopimelate decarboxylase activity
IAQ67_RS17860	COG0697	spore germination
IAQ67_RS17880	COG2172	sigma factor antagonist activity
IAQ67_RS17885	COG1366	Belongs to the anti-sigma-factor antagonist family
IAQ67_RS17890	COG1686	Belongs to the peptidase S11 family
IAQ67_RS17910	COG4974	Belongs to the 'phage' integrase family
IAQ67_RS17920	COG0735	belongs to the Fur family
IAQ67_RS17925	COG1300	Membrane
IAQ67_RS17930	COG1379	DNA repair
IAQ67_RS17935	COG0494	nUDIX hydrolase
IAQ67_RS17945	COG2195	Cleaves the N-terminal amino acid of tripeptides
IAQ67_RS17955	COG0321	lipoyl(octanoyl) transferase activity
IAQ67_RS17960	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAQ67_RS17965	COG0022	dehydrogenase e1 component
IAQ67_RS17970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAQ67_RS17975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAQ67_RS17985	COG1435	thymidine kinase activity
IAQ67_RS17990	COG4326	sporulation control protein
IAQ67_RS18010	COG0840	transmembrane signaling receptor activity
IAQ67_RS18025	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS18030	COG0750	zinc metalloprotease
IAQ67_RS18035	COG0497	DNA recombination
IAQ67_RS18040	COG1438	arginine binding
IAQ67_RS18050	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IAQ67_RS18055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IAQ67_RS18060	COG0142	geranyltranstransferase activity
IAQ67_RS18065	COG1722	exodeoxyribonuclease VII activity
IAQ67_RS18075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAQ67_RS18080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAQ67_RS18095	COG1302	Protein conserved in bacteria
IAQ67_RS18100	COG0439	Biotin carboxylase
IAQ67_RS18105	COG0511	ligase activity, forming carbon-carbon bonds
IAQ67_RS18145	COG3854	ATPases associated with a variety of cellular activities
IAQ67_RS18155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAQ67_RS18160	COG0006	proline dipeptidase activity
IAQ67_RS18175	COG3872	metal-dependent enzyme
IAQ67_RS18185	COG1752	Esterase of the alpha-beta hydrolase superfamily
IAQ67_RS18190	COG1649	PFAM Uncharacterised BCR, COG1649
IAQ67_RS18195	COG1321	iron dependent repressor
IAQ67_RS18200	COG1533	DNA photolyase activity
IAQ67_RS18205	COG0785	Cytochrome C biogenesis protein
IAQ67_RS18210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAQ67_RS18210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAQ67_RS18215	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IAQ67_RS18220	COG0735	belongs to the Fur family
IAQ67_RS18230	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAQ67_RS18235	COG1882	Formate acetyltransferase
IAQ67_RS18240	COG1454	alcohol dehydrogenase
IAQ67_RS18240	COG1012	belongs to the aldehyde dehydrogenase family
IAQ67_RS18245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAQ67_RS18250	COG3384	dioxygenase
IAQ67_RS18260	COG1733	regulation of RNA biosynthetic process
IAQ67_RS18275	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS18285	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS18295	COG3534	alpha-L-arabinofuranosidase
IAQ67_RS18310	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS18315	COG0861	Integral membrane protein TerC family
IAQ67_RS18320	COG0398	Pfam SNARE associated Golgi protein
IAQ67_RS18325	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAQ67_RS18325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAQ67_RS18335	COG4876	unkown
IAQ67_RS18340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAQ67_RS18370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAQ67_RS18375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAQ67_RS18385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAQ67_RS18390	COG1307	EDD domain protein, DegV family
IAQ67_RS18395	COG1461	Dihydroxyacetone kinase
IAQ67_RS18400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IAQ67_RS18410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAQ67_RS18415	COG1162	GTPase activity
IAQ67_RS18420	COG0515	serine threonine protein kinase
IAQ67_RS18420	COG2815	serine threonine protein kinase
IAQ67_RS18425	COG0631	protein serine/threonine phosphatase activity
IAQ67_RS18430	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IAQ67_RS18435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IAQ67_RS18435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAQ67_RS18440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IAQ67_RS18445	COG0242	peptide deformylase activity
IAQ67_RS18450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAQ67_RS18455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAQ67_RS18460	COG1758	RNA polymerase activity
IAQ67_RS18465	COG0194	GDP metabolic process
IAQ67_RS18470	COG2052	Domain of unknown function (DUF370)
IAQ67_RS18475	COG1561	YicC-like family, N-terminal region
IAQ67_RS18480	COG0646	methionine synthase
IAQ67_RS18480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IAQ67_RS18490	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IAQ67_RS18495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IAQ67_RS18505	COG0613	PHP domain protein
IAQ67_RS18520	COG4471	UPF0298 protein
IAQ67_RS18540	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IAQ67_RS18545	COG1473	amidohydrolase
IAQ67_RS18550	COG0772	Belongs to the SEDS family
IAQ67_RS18555	COG1302	Protein conserved in bacteria
IAQ67_RS18560	COG0387	Pfam Sodium calcium exchanger
IAQ67_RS18565	COG4838	Belongs to the UPF0358 family
IAQ67_RS18575	COG2309	aminopeptidase activity
IAQ67_RS18585	COG2199	diguanylate cyclase activity
IAQ67_RS18585	COG2203	Gaf domain
IAQ67_RS18590	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IAQ67_RS18595	COG2207	Transcriptional regulator
IAQ67_RS18595	COG3708	Transcriptional regulator
IAQ67_RS18600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IAQ67_RS18610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAQ67_RS18615	COG0454	-acetyltransferase
IAQ67_RS18620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAQ67_RS18625	COG1609	Transcriptional regulator
IAQ67_RS18640	COG0693	protein deglycase activity
IAQ67_RS18645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAQ67_RS18650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS18650	COG2190	(PTS) system
IAQ67_RS18650	COG1263	PTS System
IAQ67_RS18655	COG1832	CoA-binding protein
IAQ67_RS18660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IAQ67_RS18665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAQ67_RS18670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IAQ67_RS18685	COG4493	Belongs to the UPF0637 family
IAQ67_RS18695	COG1982	Orn Lys Arg decarboxylase major
IAQ67_RS18710	COG1234	tRNA 3'-trailer cleavage
IAQ67_RS18730	COG2146	nitrite reductase [NAD(P)H] activity
IAQ67_RS18735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ67_RS18740	COG3707	response regulator
IAQ67_RS18745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAQ67_RS18750	COG0243	molybdopterin cofactor binding
IAQ67_RS18755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ67_RS18760	COG2223	nitrite transmembrane transporter activity
IAQ67_RS18765	COG0281	malic enzyme
IAQ67_RS18770	COG0679	Auxin Efflux Carrier
IAQ67_RS18785	COG1874	Beta-galactosidase
IAQ67_RS18790	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS18795	COG4209	transmembrane transport
IAQ67_RS18805	COG4753	response regulator
IAQ67_RS18805	COG2207	Transcriptional regulator
IAQ67_RS18810	COG3275	phosphorelay sensor kinase activity
IAQ67_RS18820	COG3209	COG3209 Rhs family protein
IAQ67_RS18895	COG2197	response regulator
IAQ67_RS18940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAQ67_RS18945	COG0671	phosphoesterase, PA-phosphatase related
IAQ67_RS18960	COG2909	trisaccharide binding
IAQ67_RS18995	COG1742	UPF0060 membrane protein
IAQ67_RS19020	COG0371	Dehydrogenase
IAQ67_RS19070	COG0583	DNA-binding transcription factor activity
IAQ67_RS19085	COG1073	alpha beta
IAQ67_RS19095	COG1653	transport
IAQ67_RS19105	COG4209	transmembrane transport
IAQ67_RS19110	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS19115	COG2207	Transcriptional regulator
IAQ67_RS19120	COG2755	lipolytic protein G-D-S-L family
IAQ67_RS19155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IAQ67_RS19165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IAQ67_RS19175	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IAQ67_RS19180	COG0564	pseudouridine synthase activity
IAQ67_RS19185	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IAQ67_RS19190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAQ67_RS19205	COG3599	regulation of cell shape
IAQ67_RS19210	COG2302	S4 RNA-binding domain
IAQ67_RS19215	COG0762	integral membrane protein
IAQ67_RS19220	COG1799	cell septum assembly
IAQ67_RS19225	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IAQ67_RS19230	COG1496	oxidoreductase activity
IAQ67_RS19235	COG1873	PFAM PRC-barrel domain
IAQ67_RS19240	COG1191	sigma factor activity
IAQ67_RS19245	COG1191	sigma factor activity
IAQ67_RS19255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAQ67_RS19260	COG0849	cell division
IAQ67_RS19265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IAQ67_RS19270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAQ67_RS19275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IAQ67_RS19280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAQ67_RS19285	COG0772	Belongs to the SEDS family
IAQ67_RS19290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAQ67_RS19295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAQ67_RS19300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IAQ67_RS19310	COG0768	penicillin binding
IAQ67_RS19315	COG0768	penicillin binding
IAQ67_RS19325	COG0275	rRNA processing
IAQ67_RS19330	COG2001	Belongs to the MraZ family
IAQ67_RS19335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IAQ67_RS19340	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IAQ67_RS19345	COG4608	Belongs to the ABC transporter superfamily
IAQ67_RS19350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS19355	COG0601	transmembrane transport
IAQ67_RS19360	COG4166	transmembrane transport
IAQ67_RS19370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAQ67_RS19385	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IAQ67_RS19390	COG1316	TRANSCRIPTIONal
IAQ67_RS19395	COG1217	gtp-binding protein TYPA
IAQ67_RS19405	COG0861	Integral membrane protein TerC family
IAQ67_RS19410	COG0861	Integral membrane protein TerC family
IAQ67_RS19415	COG0301	tRNA thio-modification
IAQ67_RS19420	COG1104	cysteine desulfurase activity
IAQ67_RS19425	COG0741	lytic transglycosylase activity
IAQ67_RS19455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAQ67_RS19460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAQ67_RS19470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAQ67_RS19475	COG2384	SAM-dependent methyltransferase
IAQ67_RS19490	COG0358	DNA primase activity
IAQ67_RS19495	COG1671	Belongs to the UPF0178 family
IAQ67_RS19500	COG0751	glycine-tRNA ligase activity
IAQ67_RS19505	COG0752	glycyl-tRNA synthetase alpha subunit
IAQ67_RS19510	COG1381	Involved in DNA repair and RecF pathway recombination
IAQ67_RS19520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAQ67_RS19525	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IAQ67_RS19530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IAQ67_RS19535	COG1480	7TM receptor with intracellular HD hydrolase
IAQ67_RS19540	COG1702	phosphate starvation-inducible protein PhoH
IAQ67_RS19555	COG0531	amino acid
IAQ67_RS19565	COG4864	UPF0365 protein
IAQ67_RS19570	COG1030	water channel activity
IAQ67_RS19575	COG1610	YqeY-like protein
IAQ67_RS19580	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IAQ67_RS19585	COG0537	adenosine 5'-monophosphoramidase activity
IAQ67_RS19590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAQ67_RS19600	COG0419	ATPase involved in DNA repair
IAQ67_RS19605	COG0420	3'-5' exonuclease activity
IAQ67_RS19615	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IAQ67_RS19625	COG1283	sodium-dependent phosphate transmembrane transporter activity
IAQ67_RS19635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAQ67_RS19640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAQ67_RS19645	COG1994	Peptidase M50
IAQ67_RS19650	COG2264	protein methyltransferase activity
IAQ67_RS19675	COG3493	citrate carrier protein
IAQ67_RS19680	COG4565	transcriptional regulatory protein
IAQ67_RS19685	COG3290	protein histidine kinase activity
IAQ67_RS19705	COG1420	regulation of RNA biosynthetic process
IAQ67_RS19720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAQ67_RS19725	COG0481	GTPase activity
IAQ67_RS19735	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAQ67_RS19740	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IAQ67_RS19745	COG0268	Binds directly to 16S ribosomal RNA
IAQ67_RS19750	COG1466	dna polymerase III delta subunit
IAQ67_RS19760	COG1595	DNA-templated transcription, initiation
IAQ67_RS19765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAQ67_RS19770	COG0658	competence protein
IAQ67_RS19770	COG2333	competence protein COMEC
IAQ67_RS19780	COG1555	photosystem II stabilization
IAQ67_RS19785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAQ67_RS19790	COG0495	leucyl-tRNA aminoacylation
IAQ67_RS19795	COG1942	4-Oxalocrotonate Tautomerase
IAQ67_RS19800	COG2226	methyltransferase
IAQ67_RS19805	COG2996	Protein conserved in bacteria
IAQ67_RS19810	COG0799	negative regulation of ribosome biogenesis
IAQ67_RS19815	COG1713	HD superfamily hydrolase involved in NAD metabolism
IAQ67_RS19820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IAQ67_RS19825	COG1534	Rna-binding protein
IAQ67_RS19830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IAQ67_RS19835	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IAQ67_RS19840	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IAQ67_RS19845	COG1305	Transglutaminase-like
IAQ67_RS19855	COG0714	Associated with various cellular activities
IAQ67_RS19865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAQ67_RS19875	COG1363	Peptidase, m42
IAQ67_RS19885	COG4305	rare lipoprotein A
IAQ67_RS19895	COG1653	transport
IAQ67_RS19900	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS19905	COG4209	transmembrane transport
IAQ67_RS19910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAQ67_RS19915	COG0697	spore germination
IAQ67_RS19925	COG1683	Conserved Protein
IAQ67_RS19995	COG5609	conserved protein (DUF2294)
IAQ67_RS20005	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IAQ67_RS20010	COG3420	alginic acid biosynthetic process
IAQ67_RS20015	COG4149	molybdate abc transporter
IAQ67_RS20020	COG0725	ABC transporter, periplasmic molybdate-binding protein
IAQ67_RS20025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAQ67_RS20030	COG0314	molybdopterin synthase activity
IAQ67_RS20040	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IAQ67_RS20050	COG3383	formate dehydrogenase (NAD+) activity
IAQ67_RS20055	COG2427	Protein of unknown function (DUF1641)
IAQ67_RS20075	COG4977	sequence-specific DNA binding
IAQ67_RS20085	COG1744	ABC transporter substrate-binding protein PnrA-like
IAQ67_RS20095	COG1027	Aspartate ammonia-lyase
IAQ67_RS20110	COG1361	Conserved repeat domain
IAQ67_RS20120	COG0436	Aminotransferase
IAQ67_RS20130	COG1177	transmembrane transport
IAQ67_RS20135	COG1176	ABC-type spermidine putrescine transport system, permease component I
IAQ67_RS20145	COG1473	amidohydrolase
IAQ67_RS20150	COG2171	N-acyltransferase activity
IAQ67_RS20160	COG0697	spore germination
IAQ67_RS20165	COG2897	thiosulfate sulfurtransferase activity
IAQ67_RS20210	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
IAQ67_RS20295	COG4974	Belongs to the 'phage' integrase family
IAQ67_RS20305	COG0840	transmembrane signaling receptor activity
IAQ67_RS20320	COG1397	ADP-ribosylglycohydrolase
IAQ67_RS20340	COG0840	transmembrane signaling receptor activity
IAQ67_RS20340	COG5278	phosphoserine phosphatase activity
IAQ67_RS20345	COG3545	Serine hydrolase
IAQ67_RS20380	COG2814	Major facilitator Superfamily
IAQ67_RS20385	COG3250	beta-galactosidase activity
IAQ67_RS20390	COG4608	Belongs to the ABC transporter superfamily
IAQ67_RS20395	COG0444	Belongs to the ABC transporter superfamily
IAQ67_RS20410	COG0747	negative chemotaxis
IAQ67_RS20415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS20420	COG0601	transmembrane transport
IAQ67_RS20430	COG2814	Major facilitator Superfamily
IAQ67_RS20450	COG0596	Alpha beta hydrolase
IAQ67_RS20460	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS20465	COG2190	(PTS) system
IAQ67_RS20465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS20465	COG1263	PTS System
IAQ67_RS20470	COG3711	transcriptional antiterminator
IAQ67_RS20475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAQ67_RS20485	COG0314	molybdopterin synthase activity
IAQ67_RS20490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAQ67_RS20495	COG2223	nitrite transmembrane transporter activity
IAQ67_RS20505	COG2197	response regulator
IAQ67_RS20510	COG4585	Histidine kinase
IAQ67_RS20520	COG2181	nitrate reductase activity
IAQ67_RS20530	COG1140	nitrate reductase beta subunit
IAQ67_RS20535	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IAQ67_RS20540	COG4149	molybdate abc transporter
IAQ67_RS20545	COG0725	ABC transporter, periplasmic molybdate-binding protein
IAQ67_RS20555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IAQ67_RS20560	COG0535	radical SAM domain protein
IAQ67_RS20620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAQ67_RS20625	COG0436	Aminotransferase
IAQ67_RS20630	COG1464	Belongs to the NlpA lipoprotein family
IAQ67_RS20635	COG1388	LysM domain
IAQ67_RS20650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAQ67_RS20655	COG2169	Transcriptional regulator
IAQ67_RS20660	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IAQ67_RS20685	COG2814	Major facilitator Superfamily
IAQ67_RS20695	COG4221	oxidoreductase activity
IAQ67_RS20705	COG2207	Transcriptional regulator
IAQ67_RS20720	COG1063	alcohol dehydrogenase
IAQ67_RS20730	COG2304	oxidoreductase activity
IAQ67_RS20735	COG1113	amino acid transport
IAQ67_RS20785	COG0778	Nitroreductase
IAQ67_RS20790	COG1846	Transcriptional regulator
IAQ67_RS20795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAQ67_RS20805	COG0312	modulator of DNA gyrase
IAQ67_RS20810	COG0312	modulator of DNA gyrase
IAQ67_RS20890	COG0693	protein deglycase activity
IAQ67_RS20955	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS20975	COG2972	Histidine kinase
IAQ67_RS20980	COG0673	inositol 2-dehydrogenase activity
IAQ67_RS20990	COG1917	Cupin 2, conserved barrel domain protein
IAQ67_RS21000	COG1609	Transcriptional regulator
IAQ67_RS21005	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IAQ67_RS21015	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAQ67_RS21045	COG3866	Pectate lyase
IAQ67_RS21050	COG0444	Belongs to the ABC transporter superfamily
IAQ67_RS21055	COG2205	protein histidine kinase activity
IAQ67_RS21055	COG2770	Histidine kinase
IAQ67_RS21060	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS21075	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IAQ67_RS21095	COG1595	DNA-templated transcription, initiation
IAQ67_RS21120	COG4412	M6 family metalloprotease domain protein
IAQ67_RS21120	COG1404	Belongs to the peptidase S8 family
IAQ67_RS21125	COG4412	M6 family metalloprotease domain protein
IAQ67_RS21125	COG1404	Belongs to the peptidase S8 family
IAQ67_RS21130	COG0659	secondary active sulfate transmembrane transporter activity
IAQ67_RS21145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAQ67_RS21150	COG2814	Major facilitator Superfamily
IAQ67_RS21155	COG1126	abc transporter atp-binding protein
IAQ67_RS21160	COG0765	amino acid transport
IAQ67_RS21165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAQ67_RS21175	COG2261	transglycosylase associated protein
IAQ67_RS21185	COG3458	cephalosporin-C deacetylase activity
IAQ67_RS21195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ67_RS21210	COG2376	Dihydroxyacetone kinase
IAQ67_RS21220	COG2169	Transcriptional regulator
IAQ67_RS21325	COG0484	heat shock protein binding
IAQ67_RS21345	COG2815	serine threonine protein kinase
IAQ67_RS21345	COG0515	serine threonine protein kinase
IAQ67_RS21350	COG2223	nitrite transmembrane transporter activity
IAQ67_RS21355	COG3279	Response regulator of the LytR AlgR family
IAQ67_RS21360	COG3275	phosphorelay sensor kinase activity
IAQ67_RS21365	COG1619	proteins homologs of microcin C7 resistance protein MccF
IAQ67_RS21370	COG0840	transmembrane signaling receptor activity
IAQ67_RS21375	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IAQ67_RS21380	COG1523	belongs to the glycosyl hydrolase 13 family
IAQ67_RS21385	COG1132	(ABC) transporter
IAQ67_RS21390	COG4988	ABC transporter
IAQ67_RS21395	COG0246	Mannitol dehydrogenase
IAQ67_RS21400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAQ67_RS21405	COG3711	transcriptional antiterminator
IAQ67_RS21425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IAQ67_RS21430	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IAQ67_RS21435	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IAQ67_RS21450	COG1263	PTS System
IAQ67_RS21450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS21450	COG2190	(PTS) system
IAQ67_RS21455	COG3711	transcriptional antiterminator
IAQ67_RS21460	COG2268	Band 7 protein
IAQ67_RS21470	COG1979	alcohol dehydrogenase
IAQ67_RS21475	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IAQ67_RS21480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAQ67_RS21485	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IAQ67_RS21495	COG0667	Aldo Keto reductase
IAQ67_RS21500	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IAQ67_RS21505	COG0546	phosphoglycolate phosphatase activity
IAQ67_RS21515	COG3594	Acyltransferase
IAQ67_RS21525	COG0129	dihydroxy-acid dehydratase activity
IAQ67_RS21535	COG0628	permease
IAQ67_RS21540	COG0768	penicillin binding
IAQ67_RS21545	COG0840	transmembrane signaling receptor activity
IAQ67_RS21550	COG0826	peptidase U32
IAQ67_RS21555	COG0826	peptidase U32
IAQ67_RS21560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAQ67_RS21570	COG3906	Belongs to the UPF0473 family
IAQ67_RS21580	COG4472	Bacterial protein of unknown function (DUF965)
IAQ67_RS21585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IAQ67_RS21590	COG0628	permease
IAQ67_RS21610	COG1104	cysteine desulfurase activity
IAQ67_RS21615	COG1959	2 iron, 2 sulfur cluster binding
IAQ67_RS21620	COG0482	sulfurtransferase activity
IAQ67_RS21625	COG2326	polyphosphate kinase activity
IAQ67_RS21630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAQ67_RS21635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAQ67_RS21640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IAQ67_RS21645	COG3973	AAA domain
IAQ67_RS21650	COG1132	(ABC) transporter
IAQ67_RS21660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IAQ67_RS21665	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IAQ67_RS21670	COG0124	histidyl-tRNA synthetase
IAQ67_RS21680	COG0693	protein deglycase activity
IAQ67_RS21690	COG1490	D-aminoacyl-tRNA deacylase activity
IAQ67_RS21695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAQ67_RS21705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAQ67_RS21710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IAQ67_RS21710	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IAQ67_RS21720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAQ67_RS21725	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAQ67_RS21725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAQ67_RS21735	COG2244	polysaccharide biosynthetic process
IAQ67_RS21740	COG2323	membrane
IAQ67_RS21750	COG1862	Preprotein translocase
IAQ67_RS21760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IAQ67_RS21765	COG2385	sporulation resulting in formation of a cellular spore
IAQ67_RS21765	COG2385	sporulation resulting in formation of a cellular spore
IAQ67_RS21770	COG2255	four-way junction helicase activity
IAQ67_RS21775	COG0632	four-way junction helicase activity
IAQ67_RS21780	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IAQ67_RS21865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAQ67_RS21870	COG0077	Prephenate dehydratase
IAQ67_RS21875	COG0083	homoserine kinase activity
IAQ67_RS21880	COG0460	homoserine dehydrogenase
IAQ67_RS21885	COG4492	Belongs to the UPF0735 family
IAQ67_RS21890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IAQ67_RS21905	COG2868	ribosomal protein
IAQ67_RS21910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IAQ67_RS21920	COG1994	Peptidase M50
IAQ67_RS21930	COG2894	cell division
IAQ67_RS21935	COG0850	regulation of cytokinetic process
IAQ67_RS21950	COG1077	Cell shape determining protein MreB Mrl
IAQ67_RS21955	COG2003	Belongs to the UPF0758 family
IAQ67_RS21960	COG0424	maF-like protein
IAQ67_RS21975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAQ67_RS21980	COG0285	dihydrofolate synthase activity
IAQ67_RS21985	COG0525	valine-tRNA ligase activity
IAQ67_RS21990	COG1388	LysM domain
IAQ67_RS21995	COG0564	pseudouridine synthase activity
IAQ67_RS22000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IAQ67_RS22005	COG0113	porphobilinogen synthase activity
IAQ67_RS22020	COG1648	precorrin-2 dehydrogenase activity
IAQ67_RS22020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAQ67_RS22035	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IAQ67_RS22045	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IAQ67_RS22055	COG1067	ATP-dependent peptidase activity
IAQ67_RS22055	COG0470	DNA polymerase III
IAQ67_RS22065	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IAQ67_RS22070	COG0740	serine-type endopeptidase activity
IAQ67_RS22075	COG0544	peptidyl-prolyl cis-trans isomerase activity
IAQ67_RS22095	COG0708	Exodeoxyribonuclease III
IAQ67_RS22105	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS22110	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS22115	COG1175	transmembrane transport
IAQ67_RS22130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAQ67_RS22135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IAQ67_RS22140	COG1263	PTS System
IAQ67_RS22140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS22160	COG3052	prosthetic group binding
IAQ67_RS22175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IAQ67_RS22180	COG0583	DNA-binding transcription factor activity
IAQ67_RS22195	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS22205	COG1115	amino acid carrier protein
IAQ67_RS22210	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS22215	COG1609	Transcriptional regulator
IAQ67_RS22220	COG3711	transcriptional antiterminator
IAQ67_RS22225	COG1263	PTS System
IAQ67_RS22225	COG2190	(PTS) system
IAQ67_RS22225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS22235	COG0662	Cupin 2, conserved barrel domain protein
IAQ67_RS22235	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IAQ67_RS22240	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS22265	COG1216	Glycosyl transferase, family 2
IAQ67_RS22265	COG1442	glycosyl transferase family 8
IAQ67_RS22285	COG0281	malic enzyme
IAQ67_RS22290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAQ67_RS22295	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IAQ67_RS22300	COG0351	phosphomethylpyrimidine kinase
IAQ67_RS22305	COG0352	thiamine-phosphate diphosphorylase activity
IAQ67_RS22320	COG1609	Transcriptional regulator
IAQ67_RS22325	COG1486	melibiose metabolic process
IAQ67_RS22330	COG0384	phenazine biosynthesis protein PhzF
IAQ67_RS22355	COG0367	asparagine synthase
IAQ67_RS22360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IAQ67_RS22365	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IAQ67_RS22370	COG5401	PFAM Sporulation and spore germination
IAQ67_RS22375	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IAQ67_RS22385	COG0300	oxidoreductase activity
IAQ67_RS22395	COG0702	epimerase
IAQ67_RS22405	COG2226	methyltransferase
IAQ67_RS22410	COG1801	Protein of unknown function DUF72
IAQ67_RS22415	COG0463	Glycosyl transferase, family 2
IAQ67_RS22415	COG0457	Tetratricopeptide repeat
IAQ67_RS22430	COG1086	Polysaccharide biosynthesis protein
IAQ67_RS22445	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IAQ67_RS22445	COG2755	lipolytic protein G-D-S-L family
IAQ67_RS22455	COG0840	transmembrane signaling receptor activity
IAQ67_RS22465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAQ67_RS22470	COG0500	methyltransferase
IAQ67_RS22490	COG2197	response regulator
IAQ67_RS22495	COG2822	iron ion transport
IAQ67_RS22500	COG2837	iron assimilation
IAQ67_RS22505	COG0672	)-iron permease
IAQ67_RS22540	COG1131	(ABC) transporter
IAQ67_RS22550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAQ67_RS22570	COG1737	Transcriptional regulator
IAQ67_RS22575	COG0363	glucosamine-6-phosphate deaminase activity
IAQ67_RS22580	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IAQ67_RS22655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS22655	COG2190	(PTS) system
IAQ67_RS22655	COG1263	PTS System
IAQ67_RS22660	COG3192	ethanolamine utilization protein
IAQ67_RS22675	COG1609	Transcriptional regulator
IAQ67_RS22680	COG0492	ferredoxin-NADP+ reductase activity
IAQ67_RS22690	COG3711	transcriptional antiterminator
IAQ67_RS22690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAQ67_RS22695	COG1447	Phosphotransferase system cellobiose-specific component IIA
IAQ67_RS22700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAQ67_RS22705	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS22770	COG0463	Glycosyl transferase, family 2
IAQ67_RS22785	COG1086	Polysaccharide biosynthesis protein
IAQ67_RS22830	COG1216	Glycosyl transferase, family 2
IAQ67_RS22830	COG0438	transferase activity, transferring glycosyl groups
IAQ67_RS22835	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IAQ67_RS22840	COG1216	Glycosyl transferase, family 2
IAQ67_RS22855	COG3227	Zinc metalloprotease (Elastase)
IAQ67_RS22860	COG3227	Zinc metalloprotease (Elastase)
IAQ67_RS22880	COG0688	phosphatidylethanolamine metabolic process
IAQ67_RS22905	COG1131	(ABC) transporter
IAQ67_RS22915	COG0300	oxidoreductase activity
IAQ67_RS22925	COG0583	DNA-binding transcription factor activity
IAQ67_RS22930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IAQ67_RS22935	COG2357	RelA SpoT domain protein
IAQ67_RS22955	COG1408	metallophosphoesterase
IAQ67_RS22960	COG2746	aminoglycoside 3-N-acetyltransferase activity
IAQ67_RS22965	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IAQ67_RS22970	COG1053	succinate dehydrogenase
IAQ67_RS22975	COG2009	succinate dehydrogenase
IAQ67_RS22980	COG0583	DNA-binding transcription factor activity
IAQ67_RS22985	COG0569	domain protein
IAQ67_RS22990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAQ67_RS23000	COG0322	excinuclease ABC activity
IAQ67_RS23005	COG3118	belongs to the thioredoxin family
IAQ67_RS23010	COG1484	DNA-dependent DNA replication
IAQ67_RS23020	COG3253	May function as heme-dependent peroxidase
IAQ67_RS23025	COG1252	NADH dehydrogenase
IAQ67_RS23030	COG0492	ferredoxin-NADP+ reductase activity
IAQ67_RS23040	COG0189	ligase activity
IAQ67_RS23045	COG0248	Ppx GppA phosphatase
IAQ67_RS23050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IAQ67_RS23060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAQ67_RS23065	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IAQ67_RS23095	COG0697	spore germination
IAQ67_RS23100	COG0583	DNA-binding transcription factor activity
IAQ67_RS23105	COG1595	DNA-templated transcription, initiation
IAQ67_RS23125	COG0316	Belongs to the HesB IscA family
IAQ67_RS23130	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IAQ67_RS23135	COG1252	NADH dehydrogenase
IAQ67_RS23145	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IAQ67_RS23150	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS23155	COG1464	Belongs to the NlpA lipoprotein family
IAQ67_RS23160	COG2011	ABC-type metal ion transport system permease component
IAQ67_RS23165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAQ67_RS23175	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IAQ67_RS23180	COG1612	heme a metabolic process
IAQ67_RS23185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAQ67_RS23205	COG0561	phosphatase activity
IAQ67_RS23210	COG0768	penicillin binding
IAQ67_RS23215	COG0768	penicillin binding
IAQ67_RS23235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IAQ67_RS23240	COG0109	protoheme IX farnesyltransferase activity
IAQ67_RS23245	COG1988	membrane-bound metal-dependent
IAQ67_RS23260	COG0180	Tryptophanyl-tRNA synthetase
IAQ67_RS23285	COG3093	addiction module antidote protein HigA
IAQ67_RS23300	COG2346	COG2346, Truncated hemoglobins
IAQ67_RS23305	COG3314	Sporulation integral membrane protein YlbJ
IAQ67_RS23310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAQ67_RS23315	COG4470	Protein conserved in bacteria
IAQ67_RS23325	COG0739	heme binding
IAQ67_RS23335	COG0667	Aldo Keto reductase
IAQ67_RS23340	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS23345	COG1175	transmembrane transport
IAQ67_RS23355	COG2972	Histidine kinase
IAQ67_RS23360	COG2204	response regulator
IAQ67_RS23370	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IAQ67_RS23380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAQ67_RS23385	COG2169	Transcriptional regulator
IAQ67_RS23390	COG1115	amino acid carrier protein
IAQ67_RS23400	COG3711	transcriptional antiterminator
IAQ67_RS23405	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS23410	COG3335	DDE superfamily endonuclease
IAQ67_RS23415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAQ67_RS23420	COG0569	domain protein
IAQ67_RS23430	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IAQ67_RS23435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IAQ67_RS23450	COG2197	response regulator
IAQ67_RS23455	COG4585	Histidine kinase
IAQ67_RS23465	COG1842	Phage shock protein A
IAQ67_RS23475	COG1842	Phage shock protein A
IAQ67_RS23485	COG2814	Major facilitator Superfamily
IAQ67_RS23500	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IAQ67_RS23505	COG0719	Fe-S assembly protein
IAQ67_RS23510	COG0719	Fe-S assembly protein
IAQ67_RS23515	COG0396	ATPase activity
IAQ67_RS23520	COG1846	Transcriptional regulator
IAQ67_RS23625	COG3858	chitin binding
IAQ67_RS23630	COG0735	belongs to the Fur family
IAQ67_RS23645	COG1285	pathogenesis
IAQ67_RS23650	COG0456	acetyltransferase
IAQ67_RS23650	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAQ67_RS23655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAQ67_RS23660	COG0154	amidase activity
IAQ67_RS23665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAQ67_RS23680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ67_RS23690	COG0586	Pfam SNARE associated Golgi protein
IAQ67_RS23715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAQ67_RS23725	COG4840	Belongs to the UPF0435 family
IAQ67_RS23730	COG1741	Belongs to the pirin family
IAQ67_RS23735	COG0671	phosphoesterase, PA-phosphatase related
IAQ67_RS23740	COG2261	transglycosylase associated protein
IAQ67_RS23755	COG0598	Magnesium transport protein CorA
IAQ67_RS23760	COG1191	sigma factor activity
IAQ67_RS23770	COG1366	Belongs to the anti-sigma-factor antagonist family
IAQ67_RS23780	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IAQ67_RS23785	COG5002	protein histidine kinase activity
IAQ67_RS23785	COG0784	Response regulator, receiver
IAQ67_RS23785	COG2205	protein histidine kinase activity
IAQ67_RS23790	COG2208	phosphoserine phosphatase activity
IAQ67_RS23820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAQ67_RS23830	COG0488	(ABC) transporter
IAQ67_RS23845	COG1120	ATPase activity
IAQ67_RS23860	COG5386	Cell surface protein
IAQ67_RS23870	COG5386	Cell surface protein
IAQ67_RS23885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS23895	COG2329	Antibiotic biosynthesis monooxygenase
IAQ67_RS23900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IAQ67_RS23905	COG1294	oxidase, subunit
IAQ67_RS23910	COG1271	oxidase subunit
IAQ67_RS23915	COG1846	Transcriptional regulator
IAQ67_RS23920	COG2814	Major facilitator Superfamily
IAQ67_RS23925	COG1413	lyase activity
IAQ67_RS23930	COG0833	amino acid
IAQ67_RS23935	COG2211	Major facilitator Superfamily
IAQ67_RS23960	COG1070	Carbohydrate kinase
IAQ67_RS23965	COG2115	Belongs to the xylose isomerase family
IAQ67_RS23975	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS23980	COG3711	transcriptional antiterminator
IAQ67_RS23985	COG2190	(PTS) system
IAQ67_RS23985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAQ67_RS23985	COG1263	PTS System
IAQ67_RS24010	COG0655	NAD(P)H dehydrogenase (quinone) activity
IAQ67_RS24015	COG1566	PFAM secretion protein HlyD family protein
IAQ67_RS24020	COG2814	Major facilitator Superfamily
IAQ67_RS24025	COG2217	Heavy metal translocating P-type atpase
IAQ67_RS24040	COG2217	Heavy metal translocating P-type atpase
IAQ67_RS24045	COG0640	Transcriptional regulator
IAQ67_RS24055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IAQ67_RS24065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAQ67_RS24070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IAQ67_RS24080	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS24095	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS24100	COG4209	transmembrane transport
IAQ67_RS24110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IAQ67_RS24115	COG4988	ABC transporter
IAQ67_RS24120	COG1294	oxidase, subunit
IAQ67_RS24125	COG1271	oxidase subunit
IAQ67_RS24130	COG2207	Transcriptional regulator
IAQ67_RS24130	COG4753	response regulator
IAQ67_RS24135	COG2972	Histidine kinase
IAQ67_RS24145	COG5039	Polysaccharide pyruvyl transferase
IAQ67_RS24170	COG1253	flavin adenine dinucleotide binding
IAQ67_RS24175	COG1968	undecaprenyl-diphosphatase activity
IAQ67_RS24180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAQ67_RS24185	COG0667	Aldo Keto reductase
IAQ67_RS24190	COG2819	hydrolase of the alpha beta superfamily
IAQ67_RS24195	COG4607	ABC-type enterochelin transport system periplasmic component
IAQ67_RS24200	COG4604	ABC transporter, ATP-binding protein
IAQ67_RS24205	COG4605	iron ion homeostasis
IAQ67_RS24210	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAQ67_RS24225	COG1136	(ABC) transporter
IAQ67_RS24240	COG0346	lactoylglutathione lyase activity
IAQ67_RS24250	COG0351	phosphomethylpyrimidine kinase
IAQ67_RS24260	COG0737	Belongs to the 5'-nucleotidase family
IAQ67_RS24265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ67_RS24275	COG3639	organic phosphonate transmembrane transporter activity
IAQ67_RS24285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAQ67_RS24290	COG4208	sulfate ABC transporter
IAQ67_RS24295	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IAQ67_RS24300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IAQ67_RS24320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IAQ67_RS24330	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IAQ67_RS24335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAQ67_RS24350	COG2390	Transcriptional regulator
IAQ67_RS24375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAQ67_RS24375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAQ67_RS24390	COG1733	regulation of RNA biosynthetic process
IAQ67_RS24395	COG1733	regulation of RNA biosynthetic process
IAQ67_RS24415	COG1846	Transcriptional regulator
IAQ67_RS24430	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAQ67_RS24435	COG1733	regulation of RNA biosynthetic process
IAQ67_RS24440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAQ67_RS24445	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAQ67_RS24450	COG0640	Transcriptional regulator
IAQ67_RS24470	COG0596	Alpha beta hydrolase
IAQ67_RS24480	COG2814	Major facilitator Superfamily
IAQ67_RS24485	COG1819	glycosyl
IAQ67_RS24495	COG2169	Transcriptional regulator
IAQ67_RS24505	COG1846	Transcriptional regulator
IAQ67_RS24505	COG0456	acetyltransferase
IAQ67_RS24520	COG2197	response regulator
IAQ67_RS24525	COG4585	Histidine kinase
IAQ67_RS24535	COG4946	Tricorn protease homolog
IAQ67_RS24535	COG1506	peptidase
IAQ67_RS24535	COG0823	Involved in the tonB-independent uptake of proteins
IAQ67_RS24540	COG4608	Belongs to the ABC transporter superfamily
IAQ67_RS24545	COG0444	Belongs to the ABC transporter superfamily
IAQ67_RS24550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS24555	COG0601	transmembrane transport
IAQ67_RS24565	COG1473	amidohydrolase
IAQ67_RS24570	COG2186	Transcriptional regulator
IAQ67_RS24585	COG1819	glycosyl
IAQ67_RS24610	COG1609	Transcriptional regulator
IAQ67_RS24615	COG2273	Hydrolase Family 16
IAQ67_RS24725	COG1132	(ABC) transporter
IAQ67_RS24730	COG1132	(ABC) transporter
IAQ67_RS24755	COG3620	sequence-specific DNA binding
IAQ67_RS24770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAQ67_RS24780	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IAQ67_RS24785	COG5662	AntiSigma factor
IAQ67_RS24790	COG1595	DNA-templated transcription, initiation
IAQ67_RS24795	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IAQ67_RS24895	COG0726	polysaccharide deacetylase
IAQ67_RS24905	COG0489	protein tyrosine kinase activity
IAQ67_RS24910	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAQ67_RS24915	COG2046	Belongs to the sulfate adenylyltransferase family
IAQ67_RS24920	COG0175	sulfate reduction
IAQ67_RS24930	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IAQ67_RS24935	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IAQ67_RS24940	COG0101	tRNA pseudouridine synthase activity
IAQ67_RS24945	COG0203	ribosomal protein L17
IAQ67_RS24950	COG0202	RNA polymerase activity
IAQ67_RS24955	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IAQ67_RS24960	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IAQ67_RS24965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IAQ67_RS24970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IAQ67_RS24980	COG0024	Methionine aminopeptidase
IAQ67_RS24985	COG0563	adenylate kinase activity
IAQ67_RS24990	COG0201	protein transport
IAQ67_RS24995	COG0200	Binds to the 23S rRNA
IAQ67_RS25000	COG1841	ribosomal large subunit assembly
IAQ67_RS25005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IAQ67_RS25010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IAQ67_RS25015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IAQ67_RS25025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAQ67_RS25030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IAQ67_RS25035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IAQ67_RS25040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IAQ67_RS25045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IAQ67_RS25050	COG0255	Belongs to the universal ribosomal protein uL29 family
IAQ67_RS25055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IAQ67_RS25060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IAQ67_RS25065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IAQ67_RS25080	COG0089	rRNA binding
IAQ67_RS25085	COG0088	Forms part of the polypeptide exit tunnel
IAQ67_RS25090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IAQ67_RS25110	COG0049	tRNA binding
IAQ67_RS25115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IAQ67_RS25120	COG1358	cellular component organization or biogenesis
IAQ67_RS25125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAQ67_RS25130	COG0085	RNA polymerase activity
IAQ67_RS25135	COG2813	Specifically methylates the guanine in position
IAQ67_RS25140	COG0222	ribosome binding
IAQ67_RS25145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IAQ67_RS25150	COG0081	regulation of translation
IAQ67_RS25155	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IAQ67_RS25160	COG0250	Participates in transcription elongation, termination and antitermination
IAQ67_RS25165	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAQ67_RS25170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IAQ67_RS25180	COG3688	RNA-binding protein containing a PIN domain
IAQ67_RS25185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAQ67_RS25190	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IAQ67_RS25195	COG0215	cysteine-tRNA ligase activity
IAQ67_RS25200	COG1045	serine acetyltransferase
IAQ67_RS25205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAQ67_RS25210	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IAQ67_RS25215	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IAQ67_RS25220	COG4956	integral membrane protein (PIN domain superfamily)
IAQ67_RS25225	COG1183	phosphatidylcholine synthase activity
IAQ67_RS25230	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IAQ67_RS25235	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IAQ67_RS25240	COG0542	response to heat
IAQ67_RS25245	COG3869	Catalyzes the specific phosphorylation of arginine residues in
IAQ67_RS25250	COG3880	PFAM UvrB UvrC protein
IAQ67_RS25285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAQ67_RS25290	COG0210	DNA helicase
IAQ67_RS25295	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IAQ67_RS25320	COG1091	dTDP-4-dehydrorhamnose reductase activity
IAQ67_RS25335	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IAQ67_RS25340	COG0438	transferase activity, transferring glycosyl groups
IAQ67_RS25350	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAQ67_RS25355	COG1215	transferase activity, transferring glycosyl groups
IAQ67_RS25370	COG1215	transferase activity, transferring glycosyl groups
IAQ67_RS25390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAQ67_RS25395	COG0463	Glycosyl transferase, family 2
IAQ67_RS25405	COG0826	peptidase U32
IAQ67_RS25420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAQ67_RS25425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ67_RS25435	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IAQ67_RS25440	COG0556	nucleotide-excision repair
IAQ67_RS25445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IAQ67_RS25450	COG1360	Flagellar Motor Protein
IAQ67_RS25495	COG3409	Peptidoglycan-binding domain 1 protein
IAQ67_RS25495	COG0793	Belongs to the peptidase S41A family
IAQ67_RS25500	COG0741	lytic transglycosylase activity
IAQ67_RS25500	COG0739	heme binding
IAQ67_RS25500	COG1196	nuclear chromosome segregation
IAQ67_RS25505	COG2177	Part of the ABC transporter FtsEX involved in
IAQ67_RS25510	COG2884	Cell division ATP-binding protein ftsE
IAQ67_RS25515	COG2720	vancomycin resistance protein
IAQ67_RS25545	COG0463	Glycosyl transferase, family 2
IAQ67_RS25560	COG0165	Argininosuccinate lyase
IAQ67_RS25565	COG0137	argininosuccinate synthase activity
IAQ67_RS25570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IAQ67_RS25580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IAQ67_RS25585	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IAQ67_RS25590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IAQ67_RS25595	COG3386	PFAM SMP-30 Gluconolaconase
IAQ67_RS25600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAQ67_RS25610	COG0653	protein targeting
IAQ67_RS25615	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAQ67_RS25625	COG1278	Cold shock
IAQ67_RS25635	COG1516	flagellar protein fliS
IAQ67_RS25640	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IAQ67_RS25660	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IAQ67_RS25685	COG0463	Glycosyl transferase, family 2
IAQ67_RS25690	COG0463	Glycosyl transferase, family 2
IAQ67_RS25690	COG0457	Tetratricopeptide repeat
IAQ67_RS25695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IAQ67_RS25700	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IAQ67_RS25705	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IAQ67_RS25715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IAQ67_RS25720	COG4786	Flagellar basal body rod
IAQ67_RS25720	COG1256	bacterial-type flagellum assembly
IAQ67_RS25740	COG1388	LysM domain
IAQ67_RS25745	COG1040	competence protein
IAQ67_RS25750	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IAQ67_RS25785	COG1309	transcriptional regulator
IAQ67_RS25790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IAQ67_RS25830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAQ67_RS25850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAQ67_RS25855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IAQ67_RS25870	COG4786	Flagellar basal body rod
IAQ67_RS25880	COG1609	Transcriptional regulator
IAQ67_RS25885	COG0739	heme binding
IAQ67_RS25890	COG2385	sporulation resulting in formation of a cellular spore
IAQ67_RS25895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAQ67_RS25905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IAQ67_RS25910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IAQ67_RS25915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IAQ67_RS25920	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IAQ67_RS25925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAQ67_RS25930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IAQ67_RS25940	COG0356	it plays a direct role in the translocation of protons across the membrane
IAQ67_RS25955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IAQ67_RS25960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IAQ67_RS25980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAQ67_RS25985	COG4475	Protein of unknown function (DUF436)
IAQ67_RS25995	COG1971	Probably functions as a manganese efflux pump
IAQ67_RS26000	COG0009	L-threonylcarbamoyladenylate synthase
IAQ67_RS26010	COG0772	Belongs to the SEDS family
IAQ67_RS26015	COG2890	protein-(glutamine-N5) methyltransferase activity
IAQ67_RS26020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAQ67_RS26025	COG0012	GTP binding
IAQ67_RS26030	COG0456	acetyltransferase
IAQ67_RS26035	COG1304	FMN binding
IAQ67_RS26060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAQ67_RS26070	COG2076	Multidrug Resistance protein
IAQ67_RS26075	COG2076	Multidrug Resistance protein
IAQ67_RS26080	COG1105	Belongs to the carbohydrate kinase PfkB family
IAQ67_RS26085	COG1522	sequence-specific DNA binding
IAQ67_RS26100	COG1279	arginine transmembrane transporter activity
IAQ67_RS26105	COG0746	molybdenum cofactor guanylyltransferase activity
IAQ67_RS26115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAQ67_RS26135	COG2814	Major facilitator Superfamily
IAQ67_RS26140	COG0243	molybdopterin cofactor binding
IAQ67_RS26150	COG2116	formate transmembrane transporter activity
IAQ67_RS26155	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAQ67_RS26160	COG0386	Belongs to the glutathione peroxidase family
IAQ67_RS26170	COG1120	ATPase activity
IAQ67_RS26175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ67_RS26180	COG0628	permease
IAQ67_RS26185	COG1316	TRANSCRIPTIONal
IAQ67_RS26190	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAQ67_RS26290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAQ67_RS26295	COG1126	abc transporter atp-binding protein
IAQ67_RS26300	COG0765	amino acid transport
IAQ67_RS26305	COG0765	amino acid transport
IAQ67_RS26310	COG0659	secondary active sulfate transmembrane transporter activity
IAQ67_RS26330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IAQ67_RS26345	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS26375	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
IAQ67_RS26400	COG1611	Belongs to the LOG family
IAQ67_RS26405	COG1587	Uroporphyrinogen-III synthase
IAQ67_RS26410	COG0531	amino acid
IAQ67_RS26425	COG0697	spore germination
IAQ67_RS26445	COG0697	spore germination
IAQ67_RS26450	COG0840	transmembrane signaling receptor activity
IAQ67_RS26455	COG2259	Doxx family
IAQ67_RS26470	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS26490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IAQ67_RS26500	COG0697	spore germination
IAQ67_RS26505	COG3706	GGDEF domain
IAQ67_RS26515	COG1472	Belongs to the glycosyl hydrolase 3 family
IAQ67_RS26520	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS26530	COG0602	queuosine metabolic process
IAQ67_RS26535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IAQ67_RS26560	COG0300	oxidoreductase activity
IAQ67_RS26580	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IAQ67_RS26585	COG0783	Belongs to the Dps family
IAQ67_RS26590	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IAQ67_RS26595	COG3842	ATPase activity
IAQ67_RS26605	COG1176	ABC-type spermidine putrescine transport system, permease component I
IAQ67_RS26695	COG0784	Response regulator, receiver
IAQ67_RS26695	COG2205	protein histidine kinase activity
IAQ67_RS26715	COG1846	Transcriptional regulator
IAQ67_RS26725	COG3706	GGDEF domain
IAQ67_RS26735	COG0583	DNA-binding transcription factor activity
IAQ67_RS26740	COG1380	Effector of murein hydrolase LrgA
IAQ67_RS26745	COG1346	cytolysis
IAQ67_RS26750	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IAQ67_RS26755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAQ67_RS26760	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IAQ67_RS26770	COG2910	NAD(P)H-binding
IAQ67_RS26795	COG2807	transmembrane transport
IAQ67_RS26800	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS26805	COG0800	Aldolase
IAQ67_RS26810	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IAQ67_RS26815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAQ67_RS26820	COG1609	Transcriptional regulator
IAQ67_RS26825	COG0534	Mate efflux family protein
IAQ67_RS26830	COG0604	alcohol dehydrogenase
IAQ67_RS26835	COG1595	DNA-templated transcription, initiation
IAQ67_RS26845	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS26850	COG1175	transmembrane transport
IAQ67_RS26855	COG1653	transport
IAQ67_RS26865	COG1131	(ABC) transporter
IAQ67_RS26870	COG0488	(ABC) transporter
IAQ67_RS26880	COG2814	Major facilitator Superfamily
IAQ67_RS26890	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
IAQ67_RS26895	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS26905	COG2182	Extracellular solute-binding protein
IAQ67_RS26910	COG2942	2-epimerase
IAQ67_RS26915	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
IAQ67_RS26920	COG1609	Transcriptional regulator
IAQ67_RS26930	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
IAQ67_RS26950	COG3507	Belongs to the glycosyl hydrolase 43 family
IAQ67_RS26955	COG1252	NADH dehydrogenase
IAQ67_RS26980	COG0588	phosphoglycerate mutase activity
IAQ67_RS27000	COG1609	Transcriptional regulator
IAQ67_RS27005	COG2195	Cleaves the N-terminal amino acid of tripeptides
IAQ67_RS27010	COG0840	transmembrane signaling receptor activity
IAQ67_RS27020	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IAQ67_RS27025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IAQ67_RS27035	COG0395	ABC-type sugar transport system, permease component
IAQ67_RS27040	COG4209	transmembrane transport
IAQ67_RS27050	COG3275	phosphorelay sensor kinase activity
IAQ67_RS27055	COG2207	Transcriptional regulator
IAQ67_RS27055	COG4753	response regulator
IAQ67_RS27075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ67_RS27080	COG1773	rubredoxin
IAQ67_RS27085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAQ67_RS27095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ67_RS27100	COG0702	epimerase
IAQ67_RS27105	COG1309	transcriptional regulator
IAQ67_RS27110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAQ67_RS27115	COG0390	transport system, permease component
IAQ67_RS27120	COG3729	General stress protein
IAQ67_RS27135	COG4185	zeta toxin
IAQ67_RS27155	COG1522	sequence-specific DNA binding
IAQ67_RS27160	COG2814	Major facilitator Superfamily
IAQ67_RS27185	COG1874	Beta-galactosidase
IAQ67_RS27185	COG0366	Alpha amylase catalytic
IAQ67_RS27205	COG1902	pentaerythritol trinitrate reductase activity
IAQ67_RS27215	COG4753	response regulator
IAQ67_RS27215	COG2207	Transcriptional regulator
IAQ67_RS27220	COG2972	Histidine kinase
IAQ67_RS27250	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IAQ67_RS27260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAQ67_RS27260	COG2755	lipolytic protein G-D-S-L family
IAQ67_RS27265	COG0733	neurotransmitter:sodium symporter activity
IAQ67_RS27275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IAQ67_RS27295	COG2223	nitrite transmembrane transporter activity
IAQ67_RS27300	COG1695	Transcriptional regulator
IAQ67_RS27305	COG2188	Transcriptional regulator
IAQ67_RS27310	COG2723	6-phospho-beta-galactosidase activity
IAQ67_RS27315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAQ67_RS27320	COG1447	Phosphotransferase system cellobiose-specific component IIA
IAQ67_RS27325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAQ67_RS27360	COG4166	transmembrane transport
IAQ67_RS27385	COG0252	asparaginase activity
IAQ67_RS27390	COG1126	abc transporter atp-binding protein
IAQ67_RS27395	COG0765	amino acid transport
IAQ67_RS27400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAQ67_RS27405	COG1124	(ABC) transporter
IAQ67_RS27415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS27420	COG0601	transmembrane transport
IAQ67_RS27425	COG0747	negative chemotaxis
IAQ67_RS27435	COG0444	Belongs to the ABC transporter superfamily
IAQ67_RS27440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS27445	COG0601	transmembrane transport
IAQ67_RS27450	COG0747	negative chemotaxis
IAQ67_RS27465	COG2233	PERMEase
IAQ67_RS27470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAQ67_RS27480	COG4806	L-rhamnose isomerase
IAQ67_RS27485	COG0235	Class ii aldolase
IAQ67_RS27490	COG2207	Transcriptional regulator
IAQ67_RS27490	COG0662	Cupin 2, conserved barrel domain protein
IAQ67_RS27500	COG2040	homocysteine
IAQ67_RS27510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAQ67_RS27515	COG4565	transcriptional regulatory protein
IAQ67_RS27520	COG3290	protein histidine kinase activity
IAQ67_RS27530	COG0167	dihydroorotate dehydrogenase activity
IAQ67_RS27535	COG0543	2 iron, 2 sulfur cluster binding
IAQ67_RS27540	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IAQ67_RS27545	COG3708	Transcriptional regulator
IAQ67_RS27545	COG2207	Transcriptional regulator
IAQ67_RS27550	COG0583	DNA-binding transcription factor activity
IAQ67_RS27555	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS27560	COG1733	regulation of RNA biosynthetic process
IAQ67_RS27565	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS27575	COG0386	Belongs to the glutathione peroxidase family
IAQ67_RS27585	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS27605	COG0322	excinuclease ABC activity
IAQ67_RS27615	COG0723	plastoquinol--plastocyanin reductase activity
IAQ67_RS27615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAQ67_RS27625	COG5577	PFAM Coat F domain
IAQ67_RS27630	COG1063	alcohol dehydrogenase
IAQ67_RS27640	COG5577	PFAM Coat F domain
IAQ67_RS27645	COG0667	Aldo Keto reductase
IAQ67_RS27655	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS27660	COG2205	protein histidine kinase activity
IAQ67_RS27665	COG1136	(ABC) transporter
IAQ67_RS27670	COG0577	efflux transmembrane transporter activity
IAQ67_RS27680	COG0667	Aldo Keto reductase
IAQ67_RS27685	COG0535	radical SAM domain protein
IAQ67_RS27695	COG2210	Belongs to the sulfur carrier protein TusA family
IAQ67_RS27710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ67_RS27725	COG2824	Alkylphosphonate utilization operon protein PhnA
IAQ67_RS27730	COG0702	epimerase
IAQ67_RS27735	COG1597	lipid kinase activity
IAQ67_RS27745	COG4589	Belongs to the CDS family
IAQ67_RS27750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAQ67_RS27755	COG0697	spore germination
IAQ67_RS27765	COG1695	Transcriptional regulator
IAQ67_RS27770	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS27775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAQ67_RS27775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAQ67_RS27775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAQ67_RS27780	COG3711	transcriptional antiterminator
IAQ67_RS27780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAQ67_RS27785	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ67_RS27790	COG0789	Transcriptional regulator
IAQ67_RS27810	COG3835	regulator
IAQ67_RS27815	COG1929	Belongs to the glycerate kinase type-1 family
IAQ67_RS27820	COG2610	gluconate transmembrane transporter activity
IAQ67_RS27855	COG3693	PFAM glycoside hydrolase, family 10
IAQ67_RS27860	COG0657	acetylesterase activity
IAQ67_RS27870	COG1309	transcriptional regulator
IAQ67_RS27900	COG2226	methyltransferase
IAQ67_RS27905	COG0494	nUDIX hydrolase
IAQ67_RS27910	COG2207	Transcriptional regulator
IAQ67_RS27915	COG4221	oxidoreductase activity
IAQ67_RS27925	COG0579	oxidoreductase
IAQ67_RS27940	COG2160	L-arabinose isomerase activity
IAQ67_RS27945	COG0235	Class ii aldolase
IAQ67_RS27955	COG1609	Transcriptional regulator
IAQ67_RS27965	COG2197	response regulator
IAQ67_RS27980	COG2353	YceI-like domain
IAQ67_RS28030	COG1396	sequence-specific DNA binding
IAQ67_RS28050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAQ67_RS28060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAQ67_RS28070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IAQ67_RS28085	COG5002	protein histidine kinase activity
IAQ67_RS28090	COG0745	RESPONSE REGULATOR receiver
IAQ67_RS28095	COG0739	heme binding
IAQ67_RS28105	COG2188	Transcriptional regulator
IAQ67_RS28110	COG0587	DNA-directed DNA polymerase activity
IAQ67_RS28135	COG3842	ATPase activity
IAQ67_RS28145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAQ67_RS28150	COG0305	Participates in initiation and elongation during chromosome replication
IAQ67_RS28155	COG0359	binds to the 23S rRNA
IAQ67_RS28160	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
IAQ67_RS28180	COG1316	TRANSCRIPTIONal
IAQ67_RS28185	COG1686	Belongs to the peptidase S11 family
IAQ67_RS28190	COG4608	Belongs to the ABC transporter superfamily
IAQ67_RS28195	COG0444	Belongs to the ABC transporter superfamily
IAQ67_RS28200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAQ67_RS28205	COG0601	transmembrane transport
IAQ67_RS28210	COG4166	transmembrane transport
IAQ67_RS28215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IAQ67_RS28220	COG0629	single-stranded DNA binding
IAQ67_RS28225	COG0360	Binds together with S18 to 16S ribosomal RNA
IAQ67_RS28245	COG4481	Protein conserved in bacteria
IAQ67_RS28250	COG0668	transmembrane transport
IAQ67_RS28265	COG1475	DNA binding
IAQ67_RS28270	COG1192	Involved in chromosome partitioning
IAQ67_RS28275	COG1475	DNA binding
IAQ67_RS28280	COG0357	Ribosomal RNA small subunit methyltransferase G
IAQ67_RS28285	COG0445	tRNA wobble uridine modification
IAQ67_RS28290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IAQ67_RS28295	COG1847	R3H domain protein
IAQ67_RS28305	COG0594	ribonuclease P activity
IAQ67_RS28310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IAQ67_RS28485	COG1780	Probably involved in ribonucleotide reductase function
IAQ67_RS28490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAQ67_RS28495	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAQ67_RS28500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IAQ67_RS28500	COG1328	CTP reductase activity
IAQ67_RS28660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAQ67_RS28745	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAQ67_RS28745	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAQ67_RS28910	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS28985	COG0741	lytic transglycosylase activity
IAQ67_RS29000	COG1191	sigma factor activity
IAQ67_RS29005	COG0756	dUTP diphosphatase activity
IAQ67_RS29060	COG4974	Belongs to the 'phage' integrase family
IAQ67_RS29145	COG0739	heme binding
IAQ67_RS29200	COG2002	toxin-antitoxin pair type II binding
IAQ67_RS29245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAQ67_RS29340	COG2002	toxin-antitoxin pair type II binding