locus-tag	class	description
ET464_RS00005	COG0004	ammonium transporteR
ET464_RS00015	COG4585	Histidine kinase
ET464_RS00020	COG2197	response regulator
ET464_RS00040	COG3328	transposase activity
ET464_RS00045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET464_RS00050	COG0745	RESPONSE REGULATOR receiver
ET464_RS00055	COG3850	Histidine kinase
ET464_RS00055	COG5002	protein histidine kinase activity
ET464_RS00060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ET464_RS00065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ET464_RS00070	COG0174	glutamine synthetase
ET464_RS00085	COG0745	RESPONSE REGULATOR receiver
ET464_RS00095	COG2002	toxin-antitoxin pair type II binding
ET464_RS00105	COG2766	serine protein kinase
ET464_RS00110	COG0840	transmembrane signaling receptor activity
ET464_RS00115	COG2308	Evidence 4 Homologs of previously reported genes of
ET464_RS00160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ET464_RS00175	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ET464_RS00180	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ET464_RS00190	COG2719	SpoVR family
ET464_RS00220	COG0438	transferase activity, transferring glycosyl groups
ET464_RS00230	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ET464_RS00260	COG4209	transmembrane transport
ET464_RS00270	COG1653	transport
ET464_RS00275	COG2207	Transcriptional regulator
ET464_RS00295	COG0395	ABC-type sugar transport system, permease component
ET464_RS00300	COG1175	transmembrane transport
ET464_RS00320	COG0561	phosphatase activity
ET464_RS00340	COG2972	Histidine kinase
ET464_RS00345	COG2204	response regulator
ET464_RS00360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ET464_RS00370	COG2718	Belongs to the UPF0229 family
ET464_RS00375	COG0420	3'-5' exonuclease activity
ET464_RS00380	COG0419	ATPase involved in DNA repair
ET464_RS00385	COG2363	Small membrane protein
ET464_RS00390	COG3300	MHYT domain
ET464_RS00390	COG5001	Diguanylate cyclase
ET464_RS00400	COG3377	Domain of unknown function (DUF1805)
ET464_RS00410	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ET464_RS00420	COG0396	ATPase activity
ET464_RS00425	COG0719	Fe-S assembly protein
ET464_RS00430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ET464_RS00435	COG0822	iron-sulfur transferase activity
ET464_RS00440	COG0719	Fe-S assembly protein
ET464_RS00450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ET464_RS00455	COG0314	molybdopterin synthase activity
ET464_RS00460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ET464_RS00465	COG0737	Belongs to the 5'-nucleotidase family
ET464_RS00475	COG0535	radical SAM domain protein
ET464_RS00480	COG1253	flavin adenine dinucleotide binding
ET464_RS00500	COG3546	catalase activity
ET464_RS00525	COG0456	acetyltransferase
ET464_RS00530	COG3401	FG-GAP repeat protein
ET464_RS00535	COG0840	transmembrane signaling receptor activity
ET464_RS00550	COG0189	ligase activity
ET464_RS00565	COG0189	ligase activity
ET464_RS00570	COG0189	ligase activity
ET464_RS00575	COG0189	ligase activity
ET464_RS00585	COG4109	DRTGG domain
ET464_RS00610	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ET464_RS00620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ET464_RS00635	COG0824	Thioesterase
ET464_RS00645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ET464_RS00655	COG0372	Belongs to the citrate synthase family
ET464_RS00660	COG0538	isocitrate dehydrogenase activity
ET464_RS00665	COG0039	L-malate dehydrogenase activity
ET464_RS00670	COG0514	ATP-dependent DNA helicase (RecQ)
ET464_RS00685	COG1349	DNA-binding transcription factor activity
ET464_RS00690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ET464_RS00695	COG0363	glucosamine-6-phosphate deaminase activity
ET464_RS00700	COG1304	FMN binding
ET464_RS00705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET464_RS00715	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ET464_RS00725	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ET464_RS00730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ET464_RS00735	COG0367	asparagine synthase
ET464_RS00755	COG2197	response regulator
ET464_RS00760	COG3850	Histidine kinase
ET464_RS00790	COG0544	peptidyl-prolyl cis-trans isomerase activity
ET464_RS00795	COG0740	serine-type endopeptidase activity
ET464_RS00800	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ET464_RS00815	COG0470	DNA polymerase III
ET464_RS00815	COG1067	ATP-dependent peptidase activity
ET464_RS00825	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ET464_RS00840	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ET464_RS00850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ET464_RS00855	COG1648	precorrin-2 dehydrogenase activity
ET464_RS00855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ET464_RS00870	COG0113	porphobilinogen synthase activity
ET464_RS00875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ET464_RS00880	COG0564	pseudouridine synthase activity
ET464_RS00885	COG1388	LysM domain
ET464_RS00885	COG1388	LysM domain
ET464_RS00890	COG0525	valine-tRNA ligase activity
ET464_RS00895	COG0285	dihydrofolate synthase activity
ET464_RS00900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ET464_RS00920	COG2003	Belongs to the UPF0758 family
ET464_RS00925	COG1077	Cell shape determining protein MreB Mrl
ET464_RS00940	COG0850	regulation of cytokinetic process
ET464_RS00945	COG2894	cell division
ET464_RS00950	COG0772	Belongs to the SEDS family
ET464_RS00960	COG1994	Peptidase M50
ET464_RS00970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ET464_RS00975	COG2868	ribosomal protein
ET464_RS00990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ET464_RS00995	COG4492	Belongs to the UPF0735 family
ET464_RS01000	COG0460	homoserine dehydrogenase
ET464_RS01005	COG0083	homoserine kinase activity
ET464_RS01010	COG0077	Prephenate dehydratase
ET464_RS01025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ET464_RS01035	COG2255	four-way junction helicase activity
ET464_RS01040	COG2385	sporulation resulting in formation of a cellular spore
ET464_RS01045	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ET464_RS01055	COG1862	Preprotein translocase
ET464_RS01065	COG2323	membrane
ET464_RS01070	COG2244	polysaccharide biosynthetic process
ET464_RS01080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET464_RS01080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET464_RS01085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET464_RS01090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ET464_RS01095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ET464_RS01095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ET464_RS01100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ET464_RS01100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ET464_RS01105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ET464_RS01110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ET464_RS01115	COG1490	D-aminoacyl-tRNA deacylase activity
ET464_RS01120	COG0124	histidyl-tRNA synthetase
ET464_RS01125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ET464_RS01130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ET464_RS01135	COG0840	transmembrane signaling receptor activity
ET464_RS01145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ET464_RS01165	COG0482	sulfurtransferase activity
ET464_RS01170	COG1959	2 iron, 2 sulfur cluster binding
ET464_RS01175	COG1104	cysteine desulfurase activity
ET464_RS01190	COG0628	permease
ET464_RS01195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ET464_RS01200	COG4472	Bacterial protein of unknown function (DUF965)
ET464_RS01220	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ET464_RS01235	COG0840	transmembrane signaling receptor activity
ET464_RS01240	COG0768	penicillin binding
ET464_RS01245	COG0628	permease
ET464_RS01255	COG0129	dihydroxy-acid dehydratase activity
ET464_RS01265	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ET464_RS01275	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ET464_RS01280	COG0720	synthase
ET464_RS01290	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ET464_RS01320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ET464_RS01330	COG3459	Glycosyltransferase 36 associated
ET464_RS01335	COG1725	Transcriptional regulator
ET464_RS01340	COG1131	(ABC) transporter
ET464_RS01360	COG0673	inositol 2-dehydrogenase activity
ET464_RS01370	COG2207	Transcriptional regulator
ET464_RS01380	COG1653	transport
ET464_RS01385	COG1175	transmembrane transport
ET464_RS01390	COG0395	ABC-type sugar transport system, permease component
ET464_RS01425	COG3328	transposase activity
ET464_RS01455	COG2368	4-hydroxyphenylacetate
ET464_RS01460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS01500	COG0673	inositol 2-dehydrogenase activity
ET464_RS01535	COG1653	transport
ET464_RS01550	COG1621	beta-fructofuranosidase activity
ET464_RS01555	COG2972	Histidine kinase
ET464_RS01560	COG2207	Transcriptional regulator
ET464_RS01560	COG4753	response regulator
ET464_RS01565	COG1653	transport
ET464_RS01570	COG4209	transmembrane transport
ET464_RS01590	COG0517	IMP dehydrogenase activity
ET464_RS01590	COG0516	GMP reductase activity
ET464_RS01595	COG0189	ligase activity
ET464_RS01600	COG2207	Transcriptional regulator
ET464_RS01620	COG0583	DNA-binding transcription factor activity
ET464_RS01640	COG1178	ABC-type Fe3 transport system permease component
ET464_RS01645	COG3842	ATPase activity
ET464_RS01660	COG1653	transport
ET464_RS01665	COG0395	ABC-type sugar transport system, permease component
ET464_RS01670	COG4209	transmembrane transport
ET464_RS01675	COG2972	Histidine kinase
ET464_RS01680	COG2207	Transcriptional regulator
ET464_RS01680	COG4753	response regulator
ET464_RS01680	COG4753	response regulator
ET464_RS01680	COG2207	Transcriptional regulator
ET464_RS01695	COG1733	regulation of RNA biosynthetic process
ET464_RS01700	COG0667	Aldo Keto reductase
ET464_RS01730	COG0805	protein transport
ET464_RS01735	COG2197	response regulator
ET464_RS01745	COG1131	(ABC) transporter
ET464_RS01760	COG0860	N-Acetylmuramoyl-L-alanine amidase
ET464_RS01765	COG1940	carbohydrate kinase activity
ET464_RS01775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ET464_RS01785	COG0714	Associated with various cellular activities
ET464_RS01795	COG1305	Transglutaminase-like
ET464_RS01800	COG0477	Major facilitator Superfamily
ET464_RS01805	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ET464_RS01810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ET464_RS01815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ET464_RS01820	COG1534	Rna-binding protein
ET464_RS01825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ET464_RS01830	COG1713	HD superfamily hydrolase involved in NAD metabolism
ET464_RS01835	COG0799	negative regulation of ribosome biogenesis
ET464_RS01845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ET464_RS01870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ET464_RS01875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ET464_RS01890	COG0384	phenazine biosynthesis protein PhzF
ET464_RS01900	COG2062	phosphohistidine phosphatase, SixA
ET464_RS01910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS01930	COG4172	Belongs to the ABC transporter superfamily
ET464_RS01960	COG3949	Membrane
ET464_RS01970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ET464_RS01990	COG2861	carbohydrate metabolic process
ET464_RS01995	COG0860	N-Acetylmuramoyl-L-alanine amidase
ET464_RS01995	COG2247	cell wall binding repeat
ET464_RS02015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ET464_RS02030	COG1011	Hydrolase
ET464_RS02060	COG1518	maintenance of DNA repeat elements
ET464_RS02065	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ET464_RS02070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ET464_RS02085	COG0667	Aldo Keto reductase
ET464_RS02090	COG3842	ATPase activity
ET464_RS02100	COG1175	transmembrane transport
ET464_RS02105	COG0395	ABC-type sugar transport system, permease component
ET464_RS02120	COG1175	transmembrane transport
ET464_RS02125	COG0395	ABC-type sugar transport system, permease component
ET464_RS02130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS02140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS02145	COG1653	transport
ET464_RS02155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS02160	COG0667	Aldo Keto reductase
ET464_RS02165	COG1132	(ABC) transporter
ET464_RS02170	COG1132	(ABC) transporter
ET464_RS02185	COG4977	sequence-specific DNA binding
ET464_RS02185	COG1917	Cupin 2, conserved barrel domain protein
ET464_RS02195	COG3250	beta-galactosidase activity
ET464_RS02200	COG2409	Drug exporters of the RND superfamily
ET464_RS02220	COG1175	transmembrane transport
ET464_RS02225	COG3833	ABC-type maltose transport systems, permease component
ET464_RS02285	COG3328	transposase activity
ET464_RS02300	COG1132	(ABC) transporter
ET464_RS02305	COG1904	glucuronate isomerase
ET464_RS02315	COG1175	transmembrane transport
ET464_RS02320	COG0395	ABC-type sugar transport system, permease component
ET464_RS02325	COG2972	Histidine kinase
ET464_RS02335	COG4753	response regulator
ET464_RS02335	COG2207	Transcriptional regulator
ET464_RS02335	COG4753	response regulator
ET464_RS02335	COG2207	Transcriptional regulator
ET464_RS02350	COG1696	Membrane protein involved in D-alanine export
ET464_RS02370	COG0741	lytic transglycosylase activity
ET464_RS02375	COG1104	cysteine desulfurase activity
ET464_RS02380	COG0301	tRNA thio-modification
ET464_RS02385	COG0861	Integral membrane protein TerC family
ET464_RS02390	COG0861	Integral membrane protein TerC family
ET464_RS02410	COG1316	TRANSCRIPTIONal
ET464_RS02420	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ET464_RS02445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ET464_RS02455	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ET464_RS02460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ET464_RS02470	COG2001	Belongs to the MraZ family
ET464_RS02475	COG0275	rRNA processing
ET464_RS02485	COG0768	penicillin binding
ET464_RS02490	COG0768	penicillin binding
ET464_RS02495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ET464_RS02500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ET464_RS02505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ET464_RS02510	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ET464_RS02515	COG0772	Belongs to the SEDS family
ET464_RS02530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ET464_RS02535	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ET464_RS02545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ET464_RS02555	COG1191	sigma factor activity
ET464_RS02560	COG1191	sigma factor activity
ET464_RS02565	COG1873	PFAM PRC-barrel domain
ET464_RS02575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ET464_RS02580	COG1799	cell septum assembly
ET464_RS02590	COG2302	S4 RNA-binding domain
ET464_RS02595	COG3599	regulation of cell shape
ET464_RS02610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ET464_RS02615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ET464_RS02620	COG0564	pseudouridine synthase activity
ET464_RS02625	COG0436	Aminotransferase
ET464_RS02630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ET464_RS02635	COG0540	Belongs to the ATCase OTCase family
ET464_RS02640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ET464_RS02650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ET464_RS02665	COG0840	transmembrane signaling receptor activity
ET464_RS02670	COG1136	(ABC) transporter
ET464_RS02670	COG0577	efflux transmembrane transporter activity
ET464_RS02720	COG0860	N-Acetylmuramoyl-L-alanine amidase
ET464_RS02740	COG4533	DNA binding
ET464_RS02745	COG4533	DNA binding
ET464_RS02750	COG0454	-acetyltransferase
ET464_RS02760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ET464_RS02775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ET464_RS02825	COG1982	Orn Lys Arg decarboxylase major
ET464_RS02835	COG0842	Transport permease protein
ET464_RS02835	COG1511	domain protein
ET464_RS02840	COG1131	(ABC) transporter
ET464_RS02845	COG4493	Belongs to the UPF0637 family
ET464_RS02855	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ET464_RS02865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ET464_RS02870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ET464_RS02875	COG1832	CoA-binding protein
ET464_RS02880	COG1263	PTS System
ET464_RS02880	COG2190	(PTS) system
ET464_RS02880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET464_RS02885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ET464_RS02910	COG0123	including yeast histone deacetylase and acetoin utilization protein
ET464_RS02915	COG0454	-acetyltransferase
ET464_RS02920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ET464_RS02925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ET464_RS02930	COG1585	Membrane protein implicated in regulation of membrane protease activity
ET464_RS02935	COG2268	Band 7 protein
ET464_RS02940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ET464_RS02965	COG4838	Belongs to the UPF0358 family
ET464_RS02970	COG0387	Pfam Sodium calcium exchanger
ET464_RS02975	COG1302	Protein conserved in bacteria
ET464_RS02980	COG0772	Belongs to the SEDS family
ET464_RS02990	COG1473	amidohydrolase
ET464_RS02995	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ET464_RS03020	COG4471	UPF0298 protein
ET464_RS03035	COG0613	PHP domain protein
ET464_RS03045	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ET464_RS03050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ET464_RS03055	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ET464_RS03060	COG2052	Domain of unknown function (DUF370)
ET464_RS03070	COG1758	RNA polymerase activity
ET464_RS03080	COG3347	Dehydrogenase
ET464_RS03080	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS03100	COG1349	DNA-binding transcription factor activity
ET464_RS03105	COG0247	lactate metabolic process
ET464_RS03110	COG1139	Iron-sulfur cluster binding protein
ET464_RS03115	COG1556	Lactate utilization protein
ET464_RS03120	COG2186	Transcriptional regulator
ET464_RS03145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ET464_RS03155	COG0242	peptide deformylase activity
ET464_RS03160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ET464_RS03165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ET464_RS03165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ET464_RS03170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ET464_RS03175	COG0631	protein serine/threonine phosphatase activity
ET464_RS03180	COG0515	serine threonine protein kinase
ET464_RS03180	COG2815	serine threonine protein kinase
ET464_RS03190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ET464_RS03205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ET464_RS03210	COG1302	Protein conserved in bacteria
ET464_RS03215	COG1461	Dihydroxyacetone kinase
ET464_RS03220	COG1307	EDD domain protein, DegV family
ET464_RS03225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ET464_RS03235	COG2135	peptidase activity
ET464_RS03245	COG0438	transferase activity, transferring glycosyl groups
ET464_RS03250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ET464_RS03265	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ET464_RS03270	COG0463	Glycosyl transferase, family 2
ET464_RS03270	COG0457	Tetratricopeptide repeat
ET464_RS03280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ET464_RS03305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ET464_RS03315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ET464_RS03320	COG1116	anion transmembrane transporter activity
ET464_RS03325	COG0084	hydrolase, TatD family'
ET464_RS03330	COG3209	COG3209 Rhs family protein
ET464_RS03350	COG0742	ribosomal rna small subunit methyltransferase
ET464_RS03355	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ET464_RS03360	COG3314	Sporulation integral membrane protein YlbJ
ET464_RS03375	COG1323	Belongs to the UPF0348 family
ET464_RS03385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ET464_RS03395	COG0416	fatty acid biosynthetic process
ET464_RS03405	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ET464_RS03410	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS03415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ET464_RS03420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ET464_RS03430	COG1196	nuclear chromosome segregation
ET464_RS03435	COG0552	protein localization to endoplasmic reticulum
ET464_RS03440	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ET464_RS03445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ET464_RS03450	COG0228	four-way junction DNA binding
ET464_RS03460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ET464_RS03470	COG0335	large ribosomal subunit rRNA binding
ET464_RS03485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ET464_RS03495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ET464_RS03500	COG0792	nuclease activity
ET464_RS03510	COG0045	succinate-CoA ligase (ADP-forming) activity
ET464_RS03515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ET464_RS03520	COG0758	DNA mediated transformation
ET464_RS03520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ET464_RS03525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ET464_RS03530	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ET464_RS03535	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ET464_RS03540	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ET464_RS03545	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ET464_RS03555	COG1558	bacterial-type flagellum-dependent cell motility
ET464_RS03560	COG1677	Flagellar hook-basal body complex protein FliE
ET464_RS03565	COG1766	The M ring may be actively involved in energy transduction
ET464_RS03570	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ET464_RS03580	COG1157	protein secretion by the type III secretion system
ET464_RS03600	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ET464_RS03610	COG4786	Flagellar basal body rod
ET464_RS03615	COG1582	Flagellar protein (FlbD)
ET464_RS03625	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ET464_RS03630	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ET464_RS03630	COG1776	CheC inhibitor of MCP methylation
ET464_RS03635	COG2201	protein-glutamate methylesterase activity
ET464_RS03640	COG3190	flagellar
ET464_RS03645	COG1338	Plays a role in the flagellum-specific transport system
ET464_RS03650	COG1987	bacterial-type flagellum assembly
ET464_RS03655	COG1684	flagellar biosynthetic protein fliR
ET464_RS03660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ET464_RS03675	COG0455	bacterial-type flagellum organization
ET464_RS03680	COG2201	protein-glutamate methylesterase activity
ET464_RS03685	COG2198	Histidine kinase
ET464_RS03685	COG0643	Histidine kinase
ET464_RS03690	COG0835	chemotaxis
ET464_RS03695	COG1776	CheC inhibitor of MCP methylation
ET464_RS03700	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ET464_RS03710	COG1191	sigma factor activity
ET464_RS03735	COG0052	Belongs to the universal ribosomal protein uS2 family
ET464_RS03740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ET464_RS03745	COG0528	UMP kinase activity
ET464_RS03750	COG0233	cytoplasmic translational termination
ET464_RS03755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ET464_RS03760	COG4589	Belongs to the CDS family
ET464_RS03765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ET464_RS03770	COG0750	zinc metalloprotease
ET464_RS03775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ET464_RS03780	COG2176	DNA-directed DNA polymerase activity
ET464_RS03785	COG0779	Required for maturation of 30S ribosomal subunits
ET464_RS03790	COG0195	Participates in both transcription termination and antitermination
ET464_RS03795	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ET464_RS03800	COG1358	cellular component organization or biogenesis
ET464_RS03805	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ET464_RS03805	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ET464_RS03810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ET464_RS03815	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ET464_RS03820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ET464_RS03825	COG0196	riboflavin kinase activity
ET464_RS03830	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ET464_RS03835	COG1185	polyribonucleotide nucleotidyltransferase activity
ET464_RS03840	COG0726	polysaccharide deacetylase
ET464_RS03845	COG0612	Peptidase, M16
ET464_RS03850	COG0756	dUTP diphosphatase activity
ET464_RS03855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ET464_RS03860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ET464_RS03865	COG0527	aspartate kinase activity
ET464_RS03875	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ET464_RS03880	COG0740	serine-type endopeptidase activity
ET464_RS03890	COG1674	ftsk spoiiie
ET464_RS03900	COG0612	Peptidase, M16
ET464_RS03905	COG0612	Peptidase, M16
ET464_RS03910	COG0300	oxidoreductase activity
ET464_RS03925	COG1426	Protein conserved in bacteria
ET464_RS03935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ET464_RS03945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ET464_RS03950	COG2137	regulation of response to DNA damage stimulus
ET464_RS03975	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ET464_RS03975	COG0674	pyruvate-flavodoxin oxidoreductase activity
ET464_RS03980	COG1013	pyruvate-flavodoxin oxidoreductase activity
ET464_RS03985	COG4869	propanediol catabolic process
ET464_RS03990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ET464_RS03995	COG4550	Control of competence regulator ComK, YlbF/YmcA
ET464_RS04015	COG2318	DinB family
ET464_RS04020	COG1268	BioY protein
ET464_RS04025	COG1122	ATPase activity
ET464_RS04030	COG1122	ATPase activity
ET464_RS04045	COG5002	protein histidine kinase activity
ET464_RS04050	COG0745	RESPONSE REGULATOR receiver
ET464_RS04055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET464_RS04060	COG0393	Putative heavy-metal-binding
ET464_RS04065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ET464_RS04065	COG0425	Belongs to the sulfur carrier protein TusA family
ET464_RS04070	COG2217	Heavy metal translocating P-type atpase
ET464_RS04085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET464_RS04090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET464_RS04095	COG1120	ATPase activity
ET464_RS04100	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ET464_RS04115	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ET464_RS04130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET464_RS04140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ET464_RS04150	COG1643	Atp-dependent helicase
ET464_RS04165	COG3326	Membrane
ET464_RS04170	COG3973	AAA domain
ET464_RS04180	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ET464_RS04185	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ET464_RS04200	COG1253	flavin adenine dinucleotide binding
ET464_RS04210	COG3069	C4-dicarboxylate transmembrane transporter activity
ET464_RS04220	COG0586	Pfam SNARE associated Golgi protein
ET464_RS04230	COG2814	Major facilitator Superfamily
ET464_RS04255	COG0402	S-adenosylhomocysteine deaminase activity
ET464_RS04260	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ET464_RS04300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ET464_RS04305	COG2080	2 iron, 2 sulfur cluster binding
ET464_RS04310	COG3648	Uricase
ET464_RS04310	COG3195	allantoin biosynthetic process
ET464_RS04315	COG2351	hydroxyisourate hydrolase activity
ET464_RS04320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ET464_RS04325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ET464_RS04330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ET464_RS04335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ET464_RS04360	COG0640	Transcriptional regulator
ET464_RS04365	COG1607	acyl-coa hydrolase
ET464_RS04370	COG0583	DNA-binding transcription factor activity
ET464_RS04380	COG4555	ABC transporter
ET464_RS04410	COG2233	PERMEase
ET464_RS04420	COG3011	Protein conserved in bacteria
ET464_RS04425	COG1376	ErfK ybiS ycfS ynhG family protein
ET464_RS04430	COG0189	ligase activity
ET464_RS04435	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS04440	COG1368	sulfuric ester hydrolase activity
ET464_RS04445	COG1227	inorganic diphosphatase activity
ET464_RS04450	COG2814	Major facilitator Superfamily
ET464_RS04455	COG4974	Belongs to the 'phage' integrase family
ET464_RS04460	COG1335	isochorismatase
ET464_RS04465	COG1070	Carbohydrate kinase
ET464_RS04480	COG1363	Peptidase, m42
ET464_RS04485	COG1012	belongs to the aldehyde dehydrogenase family
ET464_RS04505	COG0738	Major facilitator superfamily
ET464_RS04510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ET464_RS04525	COG0351	phosphomethylpyrimidine kinase
ET464_RS04535	COG1250	3-hydroxyacyl-CoA dehydrogenase
ET464_RS04545	COG0477	Major facilitator Superfamily
ET464_RS04550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ET464_RS04560	COG2814	Major facilitator Superfamily
ET464_RS04565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS04570	COG3458	cephalosporin-C deacetylase activity
ET464_RS04580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ET464_RS04595	COG3214	Protein conserved in bacteria
ET464_RS04600	COG0488	(ABC) transporter
ET464_RS04600	COG0488	(ABC) transporter
ET464_RS04615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ET464_RS04630	COG1126	abc transporter atp-binding protein
ET464_RS04640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET464_RS04665	COG0745	RESPONSE REGULATOR receiver
ET464_RS04670	COG5002	protein histidine kinase activity
ET464_RS04680	COG2329	Antibiotic biosynthesis monooxygenase
ET464_RS04700	COG0488	(ABC) transporter
ET464_RS04705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ET464_RS04710	COG0803	Belongs to the bacterial solute-binding protein 9 family
ET464_RS04715	COG0523	cobalamin synthesis protein
ET464_RS04725	COG3275	phosphorelay sensor kinase activity
ET464_RS04730	COG2207	Transcriptional regulator
ET464_RS04740	COG4209	transmembrane transport
ET464_RS04745	COG0395	ABC-type sugar transport system, permease component
ET464_RS04755	COG1472	Belongs to the glycosyl hydrolase 3 family
ET464_RS04765	COG1078	dGTPase activity
ET464_RS04770	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ET464_RS04785	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ET464_RS04800	COG0697	spore germination
ET464_RS04810	COG0640	Transcriptional regulator
ET464_RS04820	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS04825	COG0494	nUDIX hydrolase
ET464_RS04840	COG5002	protein histidine kinase activity
ET464_RS04850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ET464_RS04870	COG0300	oxidoreductase activity
ET464_RS04890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET464_RS04905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET464_RS04910	COG5566	PFAM Mor transcription activator
ET464_RS04925	COG2814	Major facilitator Superfamily
ET464_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS04950	COG3773	Cell wall hydrolase
ET464_RS04955	COG0318	PFAM AMP-dependent synthetase and ligase
ET464_RS04960	COG0183	Belongs to the thiolase family
ET464_RS04975	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS05000	COG2814	Major facilitator Superfamily
ET464_RS05025	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS05040	COG0277	FAD linked oxidase domain protein
ET464_RS05080	COG0789	Transcriptional regulator
ET464_RS05100	COG3103	Sh3 type 3 domain protein
ET464_RS05100	COG1388	LysM domain
ET464_RS05100	COG0791	NLP P60 protein
ET464_RS05110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ET464_RS05120	COG1309	transcriptional regulator
ET464_RS05150	COG0697	spore germination
ET464_RS05170	COG0697	spore germination
ET464_RS05175	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ET464_RS05195	COG2807	transmembrane transport
ET464_RS05210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ET464_RS05220	COG0697	spore germination
ET464_RS05230	COG0789	Transcriptional regulator
ET464_RS05240	COG0463	Glycosyl transferase, family 2
ET464_RS05275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ET464_RS05280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ET464_RS05285	COG2188	Transcriptional regulator
ET464_RS05295	COG0180	Tryptophanyl-tRNA synthetase
ET464_RS05315	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ET464_RS05335	COG0490	domain, Protein
ET464_RS05380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET464_RS05385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET464_RS05390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET464_RS05435	COG3693	PFAM glycoside hydrolase, family 10
ET464_RS05515	COG0423	glycine-tRNA ligase activity
ET464_RS05525	COG0697	spore germination
ET464_RS05530	COG4335	DNA alkylation repair
ET464_RS05535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ET464_RS05590	COG5263	repeat protein
ET464_RS05590	COG4193	domain, Protein
ET464_RS05600	COG3599	regulation of cell shape
ET464_RS05610	COG1664	Polymer-forming cytoskeletal
ET464_RS05615	COG0789	Transcriptional regulator
ET464_RS05620	COG1657	PFAM Prenyltransferase squalene oxidase
ET464_RS05625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ET464_RS05645	COG4474	Belongs to the UPF0398 family
ET464_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS05670	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS05675	COG4948	Mandelate Racemase Muconate Lactonizing
ET464_RS05680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ET464_RS05685	COG1312	Catalyzes the dehydration of D-mannonate
ET464_RS05690	COG1653	transport
ET464_RS05695	COG0395	ABC-type sugar transport system, permease component
ET464_RS05700	COG1175	transmembrane transport
ET464_RS05715	COG2207	Transcriptional regulator
ET464_RS05740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ET464_RS05745	COG0583	DNA-binding transcription factor activity
ET464_RS05775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ET464_RS05795	COG1199	ATP-dependent helicase activity
ET464_RS05805	COG1131	(ABC) transporter
ET464_RS05835	COG1846	Transcriptional regulator
ET464_RS05855	COG2707	UPF0756 membrane protein
ET464_RS05860	COG1132	(ABC) transporter
ET464_RS05865	COG1132	(ABC) transporter
ET464_RS05880	COG1201	RNA secondary structure unwinding
ET464_RS05885	COG2329	Antibiotic biosynthesis monooxygenase
ET464_RS05895	COG1956	GAF domain-containing protein
ET464_RS05900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET464_RS05915	COG0791	NLP P60 protein
ET464_RS05915	COG1388	LysM domain
ET464_RS05915	COG3103	Sh3 type 3 domain protein
ET464_RS05920	COG0604	alcohol dehydrogenase
ET464_RS05930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ET464_RS05950	COG4974	Belongs to the 'phage' integrase family
ET464_RS05960	COG0492	ferredoxin-NADP+ reductase activity
ET464_RS05975	COG0714	Associated with various cellular activities
ET464_RS05990	COG2258	MOSC domain
ET464_RS06000	COG2204	response regulator
ET464_RS06055	COG0493	'glutamate synthase
ET464_RS06065	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ET464_RS06070	COG1607	acyl-coa hydrolase
ET464_RS06100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ET464_RS06105	COG2860	membrane
ET464_RS06115	COG1193	negative regulation of DNA recombination
ET464_RS06120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ET464_RS06120	COG0321	lipoyl(octanoyl) transferase activity
ET464_RS06130	COG0456	acetyltransferase
ET464_RS06135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ET464_RS06135	COG3153	acetyltransferase
ET464_RS06140	COG3850	Histidine kinase
ET464_RS06140	COG5002	protein histidine kinase activity
ET464_RS06145	COG0745	RESPONSE REGULATOR receiver
ET464_RS06150	COG2815	serine threonine protein kinase
ET464_RS06150	COG0515	serine threonine protein kinase
ET464_RS06155	COG1653	transport
ET464_RS06165	COG0395	ABC-type sugar transport system, permease component
ET464_RS06170	COG1175	transmembrane transport
ET464_RS06175	COG2207	Transcriptional regulator
ET464_RS06175	COG4753	response regulator
ET464_RS06180	COG2972	Histidine kinase
ET464_RS06195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ET464_RS06200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ET464_RS06215	COG1111	helicase
ET464_RS06215	COG1205	dead DEAH box helicase
ET464_RS06220	COG1234	tRNA 3'-trailer cleavage
ET464_RS06225	COG1410	methionine synthase
ET464_RS06225	COG0646	methionine synthase
ET464_RS06230	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ET464_RS06235	COG1011	Hydrolase
ET464_RS06245	COG4224	UPF0291 protein
ET464_RS06255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ET464_RS06265	COG0174	glutamine synthetase
ET464_RS06270	COG0789	Transcriptional regulator
ET464_RS06275	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ET464_RS06280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ET464_RS06285	COG0464	growth
ET464_RS06305	COG1923	regulation of RNA biosynthetic process
ET464_RS06310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ET464_RS06315	COG2136	Putative SAM-dependent methyltransferase
ET464_RS06315	COG2521	methyltransferase
ET464_RS06320	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ET464_RS06325	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ET464_RS06340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ET464_RS06345	COG1116	anion transmembrane transporter activity
ET464_RS06350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ET464_RS06355	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ET464_RS06365	COG0288	reversible hydration of carbon dioxide
ET464_RS06370	COG1547	Domain of unknown function (DUF309)
ET464_RS06385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ET464_RS06395	COG0644	oxidoreductase
ET464_RS06415	COG1404	Belongs to the peptidase S8 family
ET464_RS06420	COG1785	Belongs to the alkaline phosphatase family
ET464_RS06430	COG4214	carbohydrate transport
ET464_RS06450	COG2072	flavoprotein involved in K transport
ET464_RS06490	COG3620	sequence-specific DNA binding
ET464_RS06495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ET464_RS06495	COG0116	Belongs to the methyltransferase superfamily
ET464_RS06505	COG2843	Capsule synthesis protein
ET464_RS06510	COG1846	Transcriptional regulator
ET464_RS06515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ET464_RS06520	COG0187	DNA topoisomerase II activity
ET464_RS06545	COG1132	(ABC) transporter
ET464_RS06550	COG1132	(ABC) transporter
ET464_RS06555	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ET464_RS06560	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ET464_RS06570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ET464_RS06580	COG0860	N-Acetylmuramoyl-L-alanine amidase
ET464_RS06580	COG1388	LysM domain
ET464_RS06595	COG0066	3-isopropylmalate dehydratase activity
ET464_RS06600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ET464_RS06605	COG0583	DNA-binding transcription factor activity
ET464_RS06610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ET464_RS06625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ET464_RS06630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ET464_RS06635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ET464_RS06640	COG1850	ribulose-bisphosphate carboxylase activity
ET464_RS06645	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ET464_RS06650	COG0235	Class ii aldolase
ET464_RS06655	COG3935	DnaD domain protein
ET464_RS06660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ET464_RS06665	COG1250	3-hydroxyacyl-CoA dehydrogenase
ET464_RS06670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ET464_RS06685	COG0402	S-adenosylhomocysteine deaminase activity
ET464_RS06690	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ET464_RS06695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ET464_RS06695	COG1199	ATP-dependent helicase activity
ET464_RS06710	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ET464_RS06715	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ET464_RS06730	COG0438	transferase activity, transferring glycosyl groups
ET464_RS06735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ET464_RS06740	COG1803	Methylglyoxal synthase
ET464_RS06745	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ET464_RS06755	COG1694	Mazg nucleotide pyrophosphohydrolase
ET464_RS06760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ET464_RS06770	COG4347	Protein of unknown function (DUF1405)
ET464_RS06785	COG0723	plastoquinol--plastocyanin reductase activity
ET464_RS06820	COG0287	Prephenate dehydrogenase
ET464_RS06825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ET464_RS06830	COG0159	tryptophan synthase activity
ET464_RS06840	COG0135	phosphoribosylanthranilate isomerase activity
ET464_RS06845	COG0134	indole-3-glycerol-phosphate synthase activity
ET464_RS06850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ET464_RS06860	COG4401	Chorismate mutase type I
ET464_RS06865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ET464_RS06870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ET464_RS06885	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ET464_RS06890	COG0163	prenyltransferase activity
ET464_RS06895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ET464_RS06900	COG2226	methyltransferase
ET464_RS06925	COG0776	regulation of translation
ET464_RS06930	COG4211	Belongs to the binding-protein-dependent transport system permease family
ET464_RS06935	COG1129	ABC transporter
ET464_RS06945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ET464_RS06985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ET464_RS06990	COG1160	GTP binding
ET464_RS07010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ET464_RS07025	COG2959	enzyme of heme biosynthesis
ET464_RS07030	COG2339	peptidase activity
ET464_RS07035	COG4862	establishment of competence for transformation
ET464_RS07050	COG1266	CAAX protease self-immunity
ET464_RS07060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ET464_RS07065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ET464_RS07075	COG5002	protein histidine kinase activity
ET464_RS07080	COG0745	RESPONSE REGULATOR receiver
ET464_RS07085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ET464_RS07090	COG1333	cytochrome c biogenesis protein
ET464_RS07095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ET464_RS07100	COG1187	pseudouridine synthase activity
ET464_RS07105	COG0700	Nucleoside recognition
ET464_RS07110	COG2715	membrane protein required for spore maturation
ET464_RS07115	COG1686	Belongs to the peptidase S11 family
ET464_RS07120	COG3874	Sporulation protein YtfJ
ET464_RS07130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ET464_RS07135	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ET464_RS07140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ET464_RS07145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ET464_RS07145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ET464_RS07155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ET464_RS07155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ET464_RS07160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ET464_RS07165	COG0019	diaminopimelate decarboxylase activity
ET464_RS07170	COG0697	spore germination
ET464_RS07190	COG2172	sigma factor antagonist activity
ET464_RS07195	COG1366	Belongs to the anti-sigma-factor antagonist family
ET464_RS07200	COG1686	Belongs to the peptidase S11 family
ET464_RS07235	COG0735	belongs to the Fur family
ET464_RS07240	COG1300	Membrane
ET464_RS07245	COG0494	nUDIX hydrolase
ET464_RS07255	COG2195	Cleaves the N-terminal amino acid of tripeptides
ET464_RS07260	COG0321	lipoyl(octanoyl) transferase activity
ET464_RS07265	COG0508	dehydrogenase complex catalyzes the overall conversion of
ET464_RS07270	COG0022	dehydrogenase e1 component
ET464_RS07275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ET464_RS07280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ET464_RS07290	COG0745	RESPONSE REGULATOR receiver
ET464_RS07295	COG0750	zinc metalloprotease
ET464_RS07300	COG0497	DNA recombination
ET464_RS07305	COG1438	arginine binding
ET464_RS07315	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ET464_RS07320	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ET464_RS07330	COG1722	exodeoxyribonuclease VII activity
ET464_RS07335	COG1570	exodeoxyribonuclease VII activity
ET464_RS07345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ET464_RS07360	COG1302	Protein conserved in bacteria
ET464_RS07365	COG0439	Biotin carboxylase
ET464_RS07370	COG0511	ligase activity, forming carbon-carbon bonds
ET464_RS07410	COG3854	ATPases associated with a variety of cellular activities
ET464_RS07430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ET464_RS07435	COG0006	proline dipeptidase activity
ET464_RS07440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ET464_RS07450	COG3872	metal-dependent enzyme
ET464_RS07460	COG1321	iron dependent repressor
ET464_RS07465	COG0785	Cytochrome C biogenesis protein
ET464_RS07475	COG1121	(ABC) transporter
ET464_RS07480	COG0803	Belongs to the bacterial solute-binding protein 9 family
ET464_RS07480	COG3443	Belongs to the bacterial solute-binding protein 9 family
ET464_RS07490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ET464_RS07495	COG0735	belongs to the Fur family
ET464_RS07550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ET464_RS07565	COG3973	AAA domain
ET464_RS07570	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ET464_RS07580	COG1119	ATPase activity
ET464_RS07610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ET464_RS07615	COG2384	SAM-dependent methyltransferase
ET464_RS07630	COG0358	DNA primase activity
ET464_RS07635	COG1671	Belongs to the UPF0178 family
ET464_RS07640	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ET464_RS07645	COG0751	glycine-tRNA ligase activity
ET464_RS07650	COG0752	glycyl-tRNA synthetase alpha subunit
ET464_RS07655	COG2814	Major facilitator Superfamily
ET464_RS07660	COG1381	Involved in DNA repair and RecF pathway recombination
ET464_RS07670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ET464_RS07680	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ET464_RS07685	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ET464_RS07690	COG1480	7TM receptor with intracellular HD hydrolase
ET464_RS07695	COG1702	phosphate starvation-inducible protein PhoH
ET464_RS07720	COG1030	water channel activity
ET464_RS07725	COG1610	YqeY-like protein
ET464_RS07730	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ET464_RS07750	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ET464_RS07755	COG0740	serine-type endopeptidase activity
ET464_RS07775	COG1283	sodium-dependent phosphate transmembrane transporter activity
ET464_RS07785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ET464_RS07790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ET464_RS07795	COG1994	Peptidase M50
ET464_RS07800	COG2264	protein methyltransferase activity
ET464_RS07810	COG1940	carbohydrate kinase activity
ET464_RS07835	COG0165	Argininosuccinate lyase
ET464_RS07865	COG0443	Heat shock 70 kDa protein
ET464_RS07875	COG1420	regulation of RNA biosynthetic process
ET464_RS07880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ET464_RS07880	COG0165	Argininosuccinate lyase
ET464_RS07885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ET464_RS07890	COG0481	GTPase activity
ET464_RS07900	COG0860	N-Acetylmuramoyl-L-alanine amidase
ET464_RS07910	COG0268	Binds directly to 16S ribosomal RNA
ET464_RS07915	COG1466	dna polymerase III delta subunit
ET464_RS07925	COG1595	DNA-templated transcription, initiation
ET464_RS07930	COG0658	competence protein
ET464_RS07930	COG2333	competence protein COMEC
ET464_RS08030	COG0038	chloride channel
ET464_RS08090	COG0210	DNA helicase
ET464_RS08095	COG0658	competence protein
ET464_RS08095	COG2333	competence protein COMEC
ET464_RS08110	COG1596	polysaccharide export
ET464_RS08110	COG1555	photosystem II stabilization
ET464_RS08115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ET464_RS08120	COG0495	leucyl-tRNA aminoacylation
ET464_RS08125	COG2205	protein histidine kinase activity
ET464_RS08130	COG0095	Lipoate-protein ligase
ET464_RS08150	COG4895	conserved protein (DUF2196)
ET464_RS08165	COG0561	phosphatase activity
ET464_RS08170	COG1187	pseudouridine synthase activity
ET464_RS08175	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ET464_RS08175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ET464_RS08180	COG2357	RelA SpoT domain protein
ET464_RS08185	COG0167	dihydroorotate dehydrogenase activity
ET464_RS08200	COG1141	Ferredoxin
ET464_RS08205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ET464_RS08210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ET464_RS08215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ET464_RS08235	COG0004	ammonium transporteR
ET464_RS08245	COG2738	Putative neutral zinc metallopeptidase
ET464_RS08255	COG0583	DNA-binding transcription factor activity
ET464_RS08260	COG0705	Rhomboid family
ET464_RS08265	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ET464_RS08280	COG5578	integral membrane protein
ET464_RS08285	COG0513	Belongs to the DEAD box helicase family
ET464_RS08305	COG5002	protein histidine kinase activity
ET464_RS08315	COG1132	(ABC) transporter
ET464_RS08355	COG1164	Oligoendopeptidase f
ET464_RS08365	COG0584	glycerophosphoryl diester phosphodiesterase
ET464_RS08370	COG2843	Capsule synthesis protein
ET464_RS08380	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ET464_RS08420	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ET464_RS08425	COG2165	general secretion pathway protein
ET464_RS08450	COG4122	O-methyltransferase activity
ET464_RS08455	COG0116	Belongs to the methyltransferase superfamily
ET464_RS08460	COG1368	sulfuric ester hydrolase activity
ET464_RS08465	COG3480	Lon protease (S16) C-terminal proteolytic domain
ET464_RS08470	COG4844	belongs to the
ET464_RS08505	COG2445	Protein of unknown function DUF86
ET464_RS08535	COG1349	DNA-binding transcription factor activity
ET464_RS08540	COG0402	S-adenosylhomocysteine deaminase activity
ET464_RS08545	COG0402	S-adenosylhomocysteine deaminase activity
ET464_RS08560	COG0154	amidase activity
ET464_RS08590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ET464_RS08600	COG0405	Gamma-glutamyltransferase
ET464_RS08605	COG1522	sequence-specific DNA binding
ET464_RS08610	COG2059	Chromate
ET464_RS08625	COG5002	protein histidine kinase activity
ET464_RS08630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ET464_RS08635	COG0784	Response regulator, receiver
ET464_RS08635	COG2205	protein histidine kinase activity
ET464_RS08640	COG2308	Evidence 4 Homologs of previously reported genes of
ET464_RS08675	COG2032	superoxide dismutase activity
ET464_RS08680	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ET464_RS08700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ET464_RS08715	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ET464_RS08725	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ET464_RS08730	COG1733	regulation of RNA biosynthetic process
ET464_RS08735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ET464_RS08745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ET464_RS08750	COG2207	Transcriptional regulator
ET464_RS08750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET464_RS08755	COG0673	inositol 2-dehydrogenase activity
ET464_RS08785	COG2140	Oxalate decarboxylase
ET464_RS08825	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ET464_RS08830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ET464_RS08845	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS08855	COG1309	transcriptional regulator
ET464_RS08865	COG4977	sequence-specific DNA binding
ET464_RS08880	COG0789	Transcriptional regulator
ET464_RS08890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET464_RS08905	COG5002	protein histidine kinase activity
ET464_RS08915	COG2197	response regulator
ET464_RS08920	COG4585	Histidine kinase
ET464_RS08925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ET464_RS08930	COG2022	thiamine diphosphate biosynthetic process
ET464_RS08940	COG0352	thiamine-phosphate diphosphorylase activity
ET464_RS08945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ET464_RS08950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ET464_RS08955	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ET464_RS08960	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ET464_RS08965	COG2378	regulation of single-species biofilm formation
ET464_RS08980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ET464_RS08985	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ET464_RS09010	COG0395	ABC-type sugar transport system, permease component
ET464_RS09015	COG4209	transmembrane transport
ET464_RS09020	COG2207	Transcriptional regulator
ET464_RS09020	COG1917	Cupin 2, conserved barrel domain protein
ET464_RS09040	COG3588	fructose-bisphosphate aldolase
ET464_RS09065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET464_RS09180	COG2226	methyltransferase
ET464_RS09185	COG1733	regulation of RNA biosynthetic process
ET464_RS09190	COG2814	Major facilitator Superfamily
ET464_RS09210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ET464_RS09220	COG0739	heme binding
ET464_RS09220	COG0741	lytic transglycosylase activity
ET464_RS09220	COG1196	nuclear chromosome segregation
ET464_RS09225	COG0237	dephospho-CoA kinase activity
ET464_RS09230	COG1971	Probably functions as a manganese efflux pump
ET464_RS09235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ET464_RS09245	COG2203	Gaf domain
ET464_RS09245	COG4251	negative regulation of phosphorylation
ET464_RS09245	COG3706	GGDEF domain
ET464_RS09245	COG5001	Diguanylate cyclase
ET464_RS09255	COG0737	Belongs to the 5'-nucleotidase family
ET464_RS09275	COG0701	Predicted permease
ET464_RS09295	COG0640	Transcriptional regulator
ET464_RS09320	COG0704	Plays a role in the regulation of phosphate uptake
ET464_RS09325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ET464_RS09340	COG0573	inorganic phosphate transmembrane transporter activity
ET464_RS09345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ET464_RS09370	COG1073	alpha beta
ET464_RS09375	COG1874	Beta-galactosidase
ET464_RS09380	COG2207	Transcriptional regulator
ET464_RS09395	COG0745	RESPONSE REGULATOR receiver
ET464_RS09400	COG5002	protein histidine kinase activity
ET464_RS09405	COG0385	Bile acid
ET464_RS09415	COG2910	NAD(P)H-binding
ET464_RS09425	COG2207	Transcriptional regulator
ET464_RS09425	COG4753	response regulator
ET464_RS09430	COG2972	Histidine kinase
ET464_RS09435	COG1653	transport
ET464_RS09445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ET464_RS09450	COG4715	Zinc finger, swim domain protein
ET464_RS09465	COG0753	catalase activity
ET464_RS09470	COG2197	response regulator
ET464_RS09480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ET464_RS09515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET464_RS09520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET464_RS09525	COG0438	transferase activity, transferring glycosyl groups
ET464_RS09535	COG0688	phosphatidylethanolamine metabolic process
ET464_RS09560	COG1131	(ABC) transporter
ET464_RS09570	COG0300	oxidoreductase activity
ET464_RS09600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ET464_RS09605	COG0436	Aminotransferase
ET464_RS09610	COG1393	Belongs to the ArsC family
ET464_RS09615	COG0564	pseudouridine synthase activity
ET464_RS09620	COG2096	Adenosyltransferase
ET464_RS09625	COG0436	Aminotransferase
ET464_RS09630	COG1522	sequence-specific DNA binding
ET464_RS09675	COG5337	Spore coat protein CotH
ET464_RS09685	COG0477	Major facilitator Superfamily
ET464_RS09695	COG3766	membrane
ET464_RS09700	COG1193	negative regulation of DNA recombination
ET464_RS09715	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ET464_RS09725	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ET464_RS09735	COG1276	copper resistance
ET464_RS09735	COG2372	response to copper ion
ET464_RS09750	COG1984	allophanate hydrolase subunit 2
ET464_RS09765	COG0395	ABC-type sugar transport system, permease component
ET464_RS09770	COG4209	transmembrane transport
ET464_RS09775	COG2972	Histidine kinase
ET464_RS09780	COG1501	Belongs to the glycosyl hydrolase 31 family
ET464_RS09805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ET464_RS09805	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ET464_RS09810	COG3384	dioxygenase
ET464_RS09815	COG1733	regulation of RNA biosynthetic process
ET464_RS09820	COG2205	protein histidine kinase activity
ET464_RS09830	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ET464_RS09835	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ET464_RS09855	COG2733	membrane
ET464_RS09865	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS09870	COG1349	DNA-binding transcription factor activity
ET464_RS09875	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ET464_RS09880	COG2819	hydrolase of the alpha beta superfamily
ET464_RS09890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET464_RS09895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET464_RS09900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET464_RS09900	COG2207	Transcriptional regulator
ET464_RS09915	COG1917	Cupin 2, conserved barrel domain protein
ET464_RS09915	COG2207	Transcriptional regulator
ET464_RS09920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ET464_RS09930	COG1904	glucuronate isomerase
ET464_RS09935	COG0673	inositol 2-dehydrogenase activity
ET464_RS09970	COG0583	DNA-binding transcription factor activity
ET464_RS09980	COG1346	cytolysis
ET464_RS09985	COG0508	dehydrogenase complex catalyzes the overall conversion of
ET464_RS09990	COG0567	Dehydrogenase, E1 component
ET464_RS10000	COG4191	Histidine kinase
ET464_RS10005	COG3693	PFAM glycoside hydrolase, family 10
ET464_RS10010	COG1191	sigma factor activity
ET464_RS10020	COG0450	alkyl hydroperoxide reductase
ET464_RS10025	COG0473	3-isopropylmalate dehydrogenase activity
ET464_RS10030	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ET464_RS10035	COG0440	acetolactate synthase activity
ET464_RS10040	COG0028	Belongs to the TPP enzyme family
ET464_RS10055	COG1842	Phage shock protein A
ET464_RS10075	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ET464_RS10080	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ET464_RS10090	COG1215	transferase activity, transferring glycosyl groups
ET464_RS10100	COG0438	transferase activity, transferring glycosyl groups
ET464_RS10110	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ET464_RS10120	COG1242	4 iron, 4 sulfur cluster binding
ET464_RS10130	COG0346	lactoylglutathione lyase activity
ET464_RS10135	COG1482	cell wall glycoprotein biosynthetic process
ET464_RS10145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET464_RS10150	COG0444	Belongs to the ABC transporter superfamily
ET464_RS10160	COG1312	Catalyzes the dehydration of D-mannonate
ET464_RS10165	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS10170	COG1959	2 iron, 2 sulfur cluster binding
ET464_RS10175	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ET464_RS10180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ET464_RS10185	COG2318	DinB family
ET464_RS10205	COG0210	DNA helicase
ET464_RS10210	COG0667	Aldo Keto reductase
ET464_RS10220	COG3409	Peptidoglycan-binding domain 1 protein
ET464_RS10220	COG0793	Belongs to the peptidase S41A family
ET464_RS10225	COG0561	phosphatase activity
ET464_RS10235	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ET464_RS10245	COG4208	sulfate ABC transporter
ET464_RS10250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ET464_RS10255	COG1739	Uncharacterized protein family UPF0029
ET464_RS10260	COG0166	Belongs to the GPI family
ET464_RS10285	COG3123	guanosine phosphorylase activity
ET464_RS10290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ET464_RS10295	COG0788	formyltetrahydrofolate deformylase activity
ET464_RS10300	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ET464_RS10405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ET464_RS10410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ET464_RS10420	COG2244	polysaccharide biosynthetic process
ET464_RS10435	COG0438	transferase activity, transferring glycosyl groups
ET464_RS10460	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ET464_RS10465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ET464_RS10470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ET464_RS10475	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ET464_RS10480	COG0489	protein tyrosine kinase activity
ET464_RS10500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ET464_RS10505	COG1494	fructose-1,6-bisphosphatase
ET464_RS10510	COG0105	UTP biosynthetic process
ET464_RS10515	COG1175	transmembrane transport
ET464_RS10520	COG0395	ABC-type sugar transport system, permease component
ET464_RS10525	COG1653	transport
ET464_RS10550	COG1132	(ABC) transporter
ET464_RS10580	COG2346	COG2346, Truncated hemoglobins
ET464_RS10585	COG3314	Sporulation integral membrane protein YlbJ
ET464_RS10595	COG4470	Protein conserved in bacteria
ET464_RS10600	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ET464_RS10615	COG0673	inositol 2-dehydrogenase activity
ET464_RS10625	COG0179	Fumarylacetoacetate (FAA) hydrolase
ET464_RS10630	COG1196	nuclear chromosome segregation
ET464_RS10630	COG0741	lytic transglycosylase activity
ET464_RS10630	COG0739	heme binding
ET464_RS10640	COG1051	belongs to the nudix hydrolase family
ET464_RS10655	COG0395	ABC-type sugar transport system, permease component
ET464_RS10660	COG4209	transmembrane transport
ET464_RS10665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ET464_RS10670	COG0569	domain protein
ET464_RS10685	COG0673	inositol 2-dehydrogenase activity
ET464_RS10695	COG0673	inositol 2-dehydrogenase activity
ET464_RS10710	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ET464_RS10715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ET464_RS10730	COG2197	response regulator
ET464_RS10735	COG4585	Histidine kinase
ET464_RS10740	COG1842	Phage shock protein A
ET464_RS10745	COG1983	PspC domain protein
ET464_RS10750	COG1842	Phage shock protein A
ET464_RS10760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ET464_RS10765	COG1959	2 iron, 2 sulfur cluster binding
ET464_RS10890	COG0735	belongs to the Fur family
ET464_RS10895	COG1285	pathogenesis
ET464_RS10900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ET464_RS10905	COG0154	amidase activity
ET464_RS10910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ET464_RS10915	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ET464_RS10950	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ET464_RS10965	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ET464_RS10970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ET464_RS10975	COG1414	Transcriptional regulator
ET464_RS10995	COG0004	ammonium transporteR
ET464_RS11005	COG2337	Toxic component of a toxin-antitoxin (TA) module
ET464_RS11010	COG0864	Transcriptional regulator
ET464_RS11015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ET464_RS11020	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ET464_RS11065	COG1609	Transcriptional regulator
ET464_RS11070	COG1609	Transcriptional regulator
ET464_RS11080	COG1131	(ABC) transporter
ET464_RS11095	COG3300	MHYT domain
ET464_RS11095	COG5001	Diguanylate cyclase
ET464_RS11105	COG0523	cobalamin synthesis protein
ET464_RS11130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ET464_RS11150	COG0517	IMP dehydrogenase activity
ET464_RS11150	COG1125	glycine betaine transport
ET464_RS11155	COG1174	glycine betaine transport
ET464_RS11160	COG1732	Glycine betaine
ET464_RS11165	COG1174	glycine betaine transport
ET464_RS11175	COG0459	protein refolding
ET464_RS11180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ET464_RS11195	COG0805	protein transport
ET464_RS11200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ET464_RS11210	COG0521	Mo-molybdopterin cofactor biosynthetic process
ET464_RS11215	COG0315	cyclic pyranopterin monophosphate synthase activity
ET464_RS11220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ET464_RS11225	COG0488	(ABC) transporter
ET464_RS11230	COG2197	response regulator
ET464_RS11235	COG4585	Histidine kinase
ET464_RS11240	COG0142	geranyltranstransferase activity
ET464_RS11250	COG1131	(ABC) transporter
ET464_RS11255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ET464_RS11260	COG0456	acetyltransferase
ET464_RS11265	COG1214	PFAM Peptidase M22, glycoprotease
ET464_RS11270	COG0802	atpase or kinase
ET464_RS11275	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ET464_RS11280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ET464_RS11325	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ET464_RS11330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ET464_RS11335	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ET464_RS11340	COG1917	Cupin 2, conserved barrel domain protein
ET464_RS11340	COG4977	sequence-specific DNA binding
ET464_RS11355	COG0598	Magnesium transport protein CorA
ET464_RS11380	COG4124	Belongs to the glycosyl hydrolase 26 family
ET464_RS11395	COG0672	)-iron permease
ET464_RS11400	COG2837	iron assimilation
ET464_RS11405	COG2822	iron ion transport
ET464_RS11410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ET464_RS11420	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ET464_RS11425	COG0745	RESPONSE REGULATOR receiver
ET464_RS11430	COG5002	protein histidine kinase activity
ET464_RS11445	COG1309	transcriptional regulator
ET464_RS11450	COG0477	Major facilitator Superfamily
ET464_RS11455	COG0693	protein deglycase activity
ET464_RS11465	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ET464_RS11470	COG3639	organic phosphonate transmembrane transporter activity
ET464_RS11495	COG0477	Major facilitator Superfamily
ET464_RS11500	COG2721	sulfolactate sulfo-lyase activity
ET464_RS11505	COG0246	Mannitol dehydrogenase
ET464_RS11525	COG1131	(ABC) transporter
ET464_RS11540	COG2318	DinB family
ET464_RS11545	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ET464_RS11550	COG1733	regulation of RNA biosynthetic process
ET464_RS11555	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ET464_RS11560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS11575	COG0824	Thioesterase
ET464_RS11580	COG1116	anion transmembrane transporter activity
ET464_RS11585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ET464_RS11590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ET464_RS11600	COG0351	phosphomethylpyrimidine kinase
ET464_RS11620	COG1428	Deoxynucleoside kinase
ET464_RS11630	COG0386	Belongs to the glutathione peroxidase family
ET464_RS11645	COG0326	Molecular chaperone. Has ATPase activity
ET464_RS11665	COG1012	belongs to the aldehyde dehydrogenase family
ET464_RS11670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ET464_RS11685	COG0456	acetyltransferase
ET464_RS11695	COG4608	Belongs to the ABC transporter superfamily
ET464_RS11700	COG0444	Belongs to the ABC transporter superfamily
ET464_RS11705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET464_RS11710	COG0601	transmembrane transport
ET464_RS11715	COG0747	negative chemotaxis
ET464_RS11725	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ET464_RS11735	COG4720	Psort location CytoplasmicMembrane, score
ET464_RS11765	COG1609	Transcriptional regulator
ET464_RS11770	COG2972	Histidine kinase
ET464_RS11775	COG4753	response regulator
ET464_RS11775	COG2207	Transcriptional regulator
ET464_RS11780	COG5652	VanZ like family
ET464_RS11795	COG0395	ABC-type sugar transport system, permease component
ET464_RS11800	COG4209	transmembrane transport
ET464_RS11805	COG0673	inositol 2-dehydrogenase activity
ET464_RS11820	COG1132	(ABC) transporter
ET464_RS11825	COG1132	(ABC) transporter
ET464_RS11865	COG1464	Belongs to the NlpA lipoprotein family
ET464_RS11870	COG2011	ABC-type metal ion transport system permease component
ET464_RS11875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ET464_RS11880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS11885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ET464_RS11905	COG0494	nUDIX hydrolase
ET464_RS11910	COG3397	chitin binding
ET464_RS11920	COG2971	BadF BadG BcrA BcrD
ET464_RS11925	COG1472	Belongs to the glycosyl hydrolase 3 family
ET464_RS11930	COG3876	Protein conserved in bacteria
ET464_RS11945	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ET464_RS11950	COG0395	ABC-type sugar transport system, permease component
ET464_RS11955	COG1175	transmembrane transport
ET464_RS11970	COG1737	Transcriptional regulator
ET464_RS12000	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ET464_RS12005	COG0366	Alpha amylase catalytic
ET464_RS12010	COG1609	Transcriptional regulator
ET464_RS12020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ET464_RS12030	COG2801	Transposase and inactivated derivatives
ET464_RS12045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ET464_RS12050	COG1597	lipid kinase activity
ET464_RS12060	COG4496	protein, YerC YecD
ET464_RS12070	COG0306	phosphate transporter
ET464_RS12075	COG1392	Phosphate transport regulator
ET464_RS12080	COG1470	cell adhesion involved in biofilm formation
ET464_RS12090	COG5002	protein histidine kinase activity
ET464_RS12095	COG0745	RESPONSE REGULATOR receiver
ET464_RS12110	COG1653	transport
ET464_RS12115	COG0662	Cupin 2, conserved barrel domain protein
ET464_RS12115	COG2207	Transcriptional regulator
ET464_RS12125	COG0395	ABC-type sugar transport system, permease component
ET464_RS12130	COG4209	transmembrane transport
ET464_RS12135	COG1653	transport
ET464_RS12150	COG0395	ABC-type sugar transport system, permease component
ET464_RS12155	COG4209	transmembrane transport
ET464_RS12160	COG1609	Transcriptional regulator
ET464_RS12165	COG1136	(ABC) transporter
ET464_RS12165	COG4591	ABC-type transport system involved in lipoprotein release permease component
ET464_RS12170	COG0151	Belongs to the GarS family
ET464_RS12180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ET464_RS12185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ET464_RS12190	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ET464_RS12195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ET464_RS12200	COG0047	phosphoribosylformylglycinamidine synthase activity
ET464_RS12205	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ET464_RS12210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ET464_RS12215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ET464_RS12220	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ET464_RS12225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ET464_RS12235	COG2755	lipolytic protein G-D-S-L family
ET464_RS12235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ET464_RS12280	COG0395	ABC-type sugar transport system, permease component
ET464_RS12285	COG4209	transmembrane transport
ET464_RS12290	COG1653	transport
ET464_RS12295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET464_RS12295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET464_RS12310	COG1846	Transcriptional regulator
ET464_RS12315	COG2814	Major facilitator Superfamily
ET464_RS12320	COG2252	PERMEase
ET464_RS12330	COG0519	Catalyzes the synthesis of GMP from XMP
ET464_RS12330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ET464_RS12335	COG1305	Transglutaminase-like
ET464_RS12350	COG0714	Associated with various cellular activities
ET464_RS12355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ET464_RS12370	COG4555	ABC transporter
ET464_RS12390	COG4294	response to UV
ET464_RS12400	COG1181	Belongs to the D-alanine--D-alanine ligase family
ET464_RS12415	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ET464_RS12420	COG1414	Transcriptional regulator
ET464_RS12435	COG0561	phosphatase activity
ET464_RS12465	COG0456	acetyltransferase
ET464_RS12480	COG0302	gtp cyclohydrolase
ET464_RS12495	COG0328	RNA-DNA hybrid ribonuclease activity
ET464_RS12500	COG0681	Belongs to the peptidase S26 family
ET464_RS12520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET464_RS12530	COG1069	ribulokinase activity
ET464_RS12545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ET464_RS12550	COG2205	protein histidine kinase activity
ET464_RS12560	COG0745	RESPONSE REGULATOR receiver
ET464_RS12570	COG0783	Belongs to the Dps family
ET464_RS12575	COG0179	Fumarylacetoacetate (FAA) hydrolase
ET464_RS12585	COG0488	(ABC) transporter
ET464_RS12590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ET464_RS12605	COG0800	Aldolase
ET464_RS12615	COG0861	Integral membrane protein TerC family
ET464_RS12635	COG1132	(ABC) transporter
ET464_RS12640	COG1132	(ABC) transporter
ET464_RS12645	COG1285	pathogenesis
ET464_RS12650	COG0708	Exodeoxyribonuclease III
ET464_RS12655	COG0628	permease
ET464_RS12665	COG0456	acetyltransferase
ET464_RS12670	COG1742	UPF0060 membrane protein
ET464_RS12680	COG0534	Mate efflux family protein
ET464_RS12695	COG1653	transport
ET464_RS12700	COG4753	response regulator
ET464_RS12700	COG2207	Transcriptional regulator
ET464_RS12705	COG2972	Histidine kinase
ET464_RS12710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ET464_RS12715	COG0024	Methionine aminopeptidase
ET464_RS12730	COG0318	PFAM AMP-dependent synthetase and ligase
ET464_RS12735	COG1960	acyl-CoA dehydrogenase activity
ET464_RS12740	COG0183	Belongs to the thiolase family
ET464_RS12750	COG0247	lactate metabolic process
ET464_RS12750	COG2181	nitrate reductase activity
ET464_RS12755	COG2086	electron transfer activity
ET464_RS12760	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ET464_RS12765	COG0386	Belongs to the glutathione peroxidase family
ET464_RS12790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ET464_RS12795	COG0667	Aldo Keto reductase
ET464_RS12810	COG0398	Pfam SNARE associated Golgi protein
ET464_RS12820	COG4129	membrane
ET464_RS12825	COG1970	mechanosensitive ion channel activity
ET464_RS12845	COG2223	nitrite transmembrane transporter activity
ET464_RS12865	COG1027	Aspartate ammonia-lyase
ET464_RS12880	COG0006	proline dipeptidase activity
ET464_RS12890	COG2309	aminopeptidase activity
ET464_RS12895	COG5001	Diguanylate cyclase
ET464_RS12900	COG0745	RESPONSE REGULATOR receiver
ET464_RS12905	COG0784	Response regulator, receiver
ET464_RS12905	COG5002	protein histidine kinase activity
ET464_RS12905	COG2205	protein histidine kinase activity
ET464_RS12910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ET464_RS12920	COG0659	secondary active sulfate transmembrane transporter activity
ET464_RS12925	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ET464_RS12930	COG2390	Transcriptional regulator
ET464_RS12940	COG1132	(ABC) transporter
ET464_RS12945	COG0534	Mate efflux family protein
ET464_RS12950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ET464_RS12960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ET464_RS12965	COG1177	transmembrane transport
ET464_RS12970	COG1176	ABC-type spermidine putrescine transport system, permease component I
ET464_RS12980	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ET464_RS12985	COG3118	belongs to the thioredoxin family
ET464_RS12995	COG1473	amidohydrolase
ET464_RS13000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS13015	COG1473	amidohydrolase
ET464_RS13020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS13025	COG1126	abc transporter atp-binding protein
ET464_RS13030	COG0765	amino acid transport
ET464_RS13040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET464_RS13045	COG0583	DNA-binding transcription factor activity
ET464_RS13075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ET464_RS13115	COG0735	belongs to the Fur family
ET464_RS13120	COG0583	DNA-binding transcription factor activity
ET464_RS13130	COG2706	6-phosphogluconolactonase activity
ET464_RS13135	COG1396	sequence-specific DNA binding
ET464_RS13150	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ET464_RS13170	COG0438	transferase activity, transferring glycosyl groups
ET464_RS13200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ET464_RS13205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ET464_RS13210	COG0489	protein tyrosine kinase activity
ET464_RS13215	COG3944	biosynthesis protein
ET464_RS13225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ET464_RS13230	COG1511	domain protein
ET464_RS13235	COG1846	Transcriptional regulator
ET464_RS13255	COG0667	Aldo Keto reductase
ET464_RS13285	COG4209	transmembrane transport
ET464_RS13310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ET464_RS13315	COG0791	NLP P60 protein
ET464_RS13320	COG1876	peptidase activity
ET464_RS13325	COG0789	Transcriptional regulator
ET464_RS13330	COG0667	Aldo Keto reductase
ET464_RS13345	COG5002	protein histidine kinase activity
ET464_RS13350	COG0745	RESPONSE REGULATOR receiver
ET464_RS13355	COG2182	Extracellular solute-binding protein
ET464_RS13370	COG2972	Histidine kinase
ET464_RS13375	COG4753	response regulator
ET464_RS13375	COG2207	Transcriptional regulator
ET464_RS13385	COG0626	cystathionine gamma-synthase activity
ET464_RS13395	COG2226	methyltransferase
ET464_RS13420	COG3852	Histidine kinase
ET464_RS13440	COG2205	protein histidine kinase activity
ET464_RS13445	COG0745	RESPONSE REGULATOR receiver
ET464_RS13450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ET464_RS13455	COG2357	RelA SpoT domain protein
ET464_RS13460	COG1910	domain protein
ET464_RS13465	COG0725	ABC transporter, periplasmic molybdate-binding protein
ET464_RS13470	COG4149	molybdate abc transporter
ET464_RS13485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET464_RS13505	COG0671	phosphoesterase, PA-phosphatase related
ET464_RS13510	COG2814	Major facilitator Superfamily
ET464_RS13515	COG2814	Major facilitator Superfamily
ET464_RS13520	COG0583	DNA-binding transcription factor activity
ET464_RS13525	COG0300	oxidoreductase activity
ET464_RS13530	COG1472	Belongs to the glycosyl hydrolase 3 family
ET464_RS13535	COG3693	PFAM glycoside hydrolase, family 10
ET464_RS13540	COG2363	Small membrane protein
ET464_RS13545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ET464_RS13565	COG1595	DNA-templated transcription, initiation
ET464_RS13580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ET464_RS13600	COG4608	Belongs to the ABC transporter superfamily
ET464_RS13605	COG0444	Belongs to the ABC transporter superfamily
ET464_RS13610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET464_RS13615	COG4174	ABC transporter (Permease)
ET464_RS13620	COG0747	negative chemotaxis
ET464_RS13630	COG1609	Transcriptional regulator
ET464_RS13645	COG0277	FAD linked oxidase domain protein
ET464_RS13665	COG0189	ligase activity
ET464_RS13735	COG2801	Transposase and inactivated derivatives
ET464_RS13750	COG1196	nuclear chromosome segregation
ET464_RS13755	COG1074	ATP-dependent DNA helicase activity
ET464_RS13800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ET464_RS13805	COG1278	Cold shock
ET464_RS13810	COG0557	exoribonuclease II activity
ET464_RS13815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ET464_RS13820	COG0148	phosphopyruvate hydratase activity
ET464_RS13825	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ET464_RS13830	COG0149	triose-phosphate isomerase activity
ET464_RS13835	COG0126	phosphoglycerate kinase activity
ET464_RS13855	COG0740	serine-type endopeptidase activity
ET464_RS13860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET464_RS13865	COG1481	regulation of sporulation
ET464_RS13870	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ET464_RS13875	COG1660	Displays ATPase and GTPase activities
ET464_RS13880	COG1940	carbohydrate kinase activity
ET464_RS13890	COG0457	Tetratricopeptide repeat
ET464_RS13890	COG0457	Tetratricopeptide repeat
ET464_RS13905	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ET464_RS13905	COG0140	phosphoribosyl-ATP diphosphatase activity
ET464_RS13910	COG0107	imidazoleglycerol-phosphate synthase activity
ET464_RS13915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ET464_RS13920	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ET464_RS13925	COG0131	Imidazoleglycerol-phosphate dehydratase
ET464_RS13935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ET464_RS13940	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ET464_RS13945	COG0110	maltose O-acetyltransferase activity
ET464_RS13960	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ET464_RS13975	COG3842	ATPase activity
ET464_RS13980	COG2508	Transcriptional regulator
ET464_RS13985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ET464_RS13990	COG0431	NADPH-dependent FMN reductase
ET464_RS14050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ET464_RS14055	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ET464_RS14060	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ET464_RS14075	COG0254	rRNA binding
ET464_RS14085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ET464_RS14090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ET464_RS14095	COG0191	fructose-bisphosphate aldolase activity
ET464_RS14105	COG0504	CTP synthase activity
ET464_RS14110	COG3343	RNA polymerase activity
ET464_RS14130	COG0018	arginyl-trna synthetase
ET464_RS14150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ET464_RS14165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ET464_RS14175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ET464_RS14215	COG0791	NLP P60 protein
ET464_RS14230	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ET464_RS14235	COG1360	Flagellar Motor Protein
ET464_RS14245	COG1187	pseudouridine synthase activity
ET464_RS14250	COG4191	Histidine kinase
ET464_RS14255	COG0590	tRNA wobble adenosine to inosine editing
ET464_RS14265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET464_RS14270	COG1126	abc transporter atp-binding protein
ET464_RS14285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET464_RS14290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET464_RS14295	COG0038	chloride channel
ET464_RS14310	COG1309	transcriptional regulator
ET464_RS14315	COG0492	ferredoxin-NADP+ reductase activity
ET464_RS14340	COG1940	carbohydrate kinase activity
ET464_RS14360	COG2211	Major facilitator Superfamily
ET464_RS14385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ET464_RS14405	COG0516	GMP reductase activity
ET464_RS14405	COG0517	IMP dehydrogenase activity
ET464_RS14440	COG0463	Glycosyl transferase, family 2
ET464_RS14455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ET464_RS14460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ET464_RS14465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ET464_RS14470	COG1396	sequence-specific DNA binding
ET464_RS14475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ET464_RS14480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ET464_RS14485	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ET464_RS14490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ET464_RS14495	COG0512	Glutamine amidotransferase of anthranilate synthase
ET464_RS14500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ET464_RS14505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ET464_RS14510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ET464_RS14515	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ET464_RS14530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ET464_RS14535	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ET464_RS14555	COG1744	ABC transporter substrate-binding protein PnrA-like
ET464_RS14560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ET464_RS14575	COG0515	serine threonine protein kinase
ET464_RS14580	COG2304	oxidoreductase activity
ET464_RS14590	COG2208	phosphoserine phosphatase activity
ET464_RS14595	COG1098	S1 RNA binding domain
ET464_RS14615	COG3739	integral membrane protein
ET464_RS14620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ET464_RS14630	COG3956	TIGRFAM MazG family protein
ET464_RS14635	COG1929	Belongs to the glycerate kinase type-1 family
ET464_RS14650	COG2002	toxin-antitoxin pair type II binding
ET464_RS14665	COG4608	Belongs to the ABC transporter superfamily
ET464_RS14680	COG0747	negative chemotaxis
ET464_RS14700	COG2814	Major facilitator Superfamily
ET464_RS14710	COG4211	Belongs to the binding-protein-dependent transport system permease family
ET464_RS14735	COG2207	Transcriptional regulator
ET464_RS14745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ET464_RS14760	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ET464_RS14765	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ET464_RS14770	COG2088	sporulation resulting in formation of a cellular spore
ET464_RS14775	COG0251	oxidation-reduction process
ET464_RS14780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ET464_RS14785	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ET464_RS14795	COG4466	Protein conserved in bacteria
ET464_RS14805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ET464_RS14815	COG3583	domain protein
ET464_RS14815	COG3584	3D domain protein
ET464_RS14820	COG0084	hydrolase, TatD family'
ET464_RS14825	COG1078	dGTPase activity
ET464_RS14830	COG2002	toxin-antitoxin pair type II binding
ET464_RS14835	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ET464_RS14840	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ET464_RS14845	COG4467	Involved in initiation control of chromosome replication
ET464_RS14850	COG1774	PSP1 C-terminal conserved region
ET464_RS14855	COG0470	DNA polymerase III
ET464_RS14860	COG1728	Protein conserved in bacteria
ET464_RS14865	COG3870	Protein conserved in bacteria
ET464_RS14870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ET464_RS14875	COG1982	Orn Lys Arg decarboxylase major
ET464_RS14915	COG3437	response regulator, receiver
ET464_RS14920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ET464_RS14940	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ET464_RS14945	COG2501	S4 domain
ET464_RS14950	COG0592	DNA-directed DNA polymerase activity
ET464_RS14955	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ET464_RS14960	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ET464_RS14965	COG0594	ribonuclease P activity
ET464_RS14975	COG1847	R3H domain protein
ET464_RS14980	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ET464_RS14985	COG0445	tRNA wobble uridine modification
ET464_RS14990	COG0357	Ribosomal RNA small subunit methyltransferase G
ET464_RS14995	COG1475	DNA binding
ET464_RS15000	COG1192	Involved in chromosome partitioning
ET464_RS15005	COG1475	DNA binding
ET464_RS15010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ET464_RS15030	COG0668	transmembrane transport
ET464_RS15035	COG4481	Protein conserved in bacteria
ET464_RS15055	COG0360	Binds together with S18 to 16S ribosomal RNA
ET464_RS15060	COG0629	single-stranded DNA binding
ET464_RS15065	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ET464_RS15070	COG0628	permease
ET464_RS15090	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ET464_RS15095	COG0359	binds to the 23S rRNA
ET464_RS15100	COG0305	Participates in initiation and elongation during chromosome replication
ET464_RS15105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ET464_RS15120	COG0745	RESPONSE REGULATOR receiver
ET464_RS15125	COG5002	protein histidine kinase activity
ET464_RS15140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ET464_RS15150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET464_RS15160	COG3458	cephalosporin-C deacetylase activity
ET464_RS15170	COG2315	Protein conserved in bacteria
ET464_RS15215	COG3328	transposase activity
ET464_RS15235	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS15240	COG0583	DNA-binding transcription factor activity
ET464_RS15245	COG2132	Multicopper oxidase
ET464_RS15265	COG3708	Transcriptional regulator
ET464_RS15265	COG2207	Transcriptional regulator
ET464_RS15285	COG1234	tRNA 3'-trailer cleavage
ET464_RS15290	COG0561	phosphatase activity
ET464_RS15305	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ET464_RS15310	COG0561	phosphatase activity
ET464_RS15315	COG3321	synthase
ET464_RS15315	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS15315	COG0604	alcohol dehydrogenase
ET464_RS15320	COG1309	transcriptional regulator
ET464_RS15325	COG0583	DNA-binding transcription factor activity
ET464_RS15335	COG2267	carboxylic ester hydrolase activity
ET464_RS15350	COG0534	Mate efflux family protein
ET464_RS15395	COG2188	Transcriptional regulator
ET464_RS15400	COG1840	ABC-type Fe3 transport system, periplasmic component
ET464_RS15410	COG3842	ATPase activity
ET464_RS15415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ET464_RS15440	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ET464_RS15455	COG0300	oxidoreductase activity
ET464_RS15465	COG0726	polysaccharide deacetylase
ET464_RS15470	COG0154	amidase activity
ET464_RS15475	COG1309	transcriptional regulator
ET464_RS15485	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS15490	COG0579	oxidoreductase
ET464_RS15505	COG1846	Transcriptional regulator
ET464_RS15535	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ET464_RS15540	COG4753	response regulator
ET464_RS15540	COG2207	Transcriptional regulator
ET464_RS15545	COG2972	Histidine kinase
ET464_RS15555	COG4209	transmembrane transport
ET464_RS15560	COG0395	ABC-type sugar transport system, permease component
ET464_RS15565	COG2814	Major facilitator Superfamily
ET464_RS15570	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ET464_RS15580	COG2814	Major facilitator Superfamily
ET464_RS15585	COG0789	Transcriptional regulator
ET464_RS15590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ET464_RS15595	COG4702	Belongs to the UPF0303 family
ET464_RS15600	COG0477	Major facilitator Superfamily
ET464_RS15610	COG2814	Major facilitator Superfamily
ET464_RS15615	COG1361	Conserved repeat domain
ET464_RS15635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ET464_RS15640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ET464_RS15650	COG0537	adenosine 5'-monophosphoramidase activity
ET464_RS15675	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ET464_RS15680	COG0656	L-ascorbic acid biosynthetic process
ET464_RS15685	COG2814	Major facilitator Superfamily
ET464_RS15690	COG1733	regulation of RNA biosynthetic process
ET464_RS15700	COG0789	Transcriptional regulator
ET464_RS15710	COG4533	DNA binding
ET464_RS15740	COG2195	Cleaves the N-terminal amino acid of tripeptides
ET464_RS15750	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ET464_RS15755	COG2169	Transcriptional regulator
ET464_RS15760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ET464_RS15775	COG0534	Mate efflux family protein
ET464_RS15785	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS15795	COG0583	DNA-binding transcription factor activity
ET464_RS15800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ET464_RS15810	COG1252	NADH dehydrogenase
ET464_RS15815	COG2966	Psort location CytoplasmicMembrane, score
ET464_RS15820	COG3610	response to peptide
ET464_RS15825	COG1012	belongs to the aldehyde dehydrogenase family
ET464_RS15835	COG2207	Transcriptional regulator
ET464_RS15840	COG1653	transport
ET464_RS15845	COG1653	transport
ET464_RS15850	COG4209	transmembrane transport
ET464_RS15855	COG0395	ABC-type sugar transport system, permease component
ET464_RS15860	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ET464_RS15865	COG2353	YceI-like domain
ET464_RS15875	COG0534	Mate efflux family protein
ET464_RS15890	COG0667	Aldo Keto reductase
ET464_RS15910	COG1741	Belongs to the pirin family
ET464_RS15920	COG1132	(ABC) transporter
ET464_RS15925	COG1132	(ABC) transporter
ET464_RS15930	COG0840	transmembrane signaling receptor activity
ET464_RS15935	COG1846	Transcriptional regulator
ET464_RS15955	COG1132	(ABC) transporter
ET464_RS15960	COG1695	Transcriptional regulator
ET464_RS15965	COG0252	asparaginase activity
ET464_RS15970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ET464_RS15975	COG3689	TIGRFAM TIGR03943 family protein
ET464_RS15980	COG0701	Predicted permease
ET464_RS15985	COG1368	sulfuric ester hydrolase activity
ET464_RS15990	COG1876	peptidase activity
ET464_RS16005	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ET464_RS16010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ET464_RS16015	COG0735	belongs to the Fur family
ET464_RS16020	COG0745	RESPONSE REGULATOR receiver
ET464_RS16025	COG0753	catalase activity
ET464_RS16035	COG4846	Membrane protein involved in cytochrome C biogenesis
ET464_RS16040	COG1846	Transcriptional regulator
ET464_RS16045	COG0386	Belongs to the glutathione peroxidase family
ET464_RS16055	COG0436	Aminotransferase
ET464_RS16065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ET464_RS16070	COG0640	Transcriptional regulator
ET464_RS16075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ET464_RS16080	COG2318	DinB family
ET464_RS16085	COG2322	membrane
ET464_RS16090	COG2746	aminoglycoside 3-N-acetyltransferase activity
ET464_RS16100	COG1247	-acetyltransferase
ET464_RS16110	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ET464_RS16110	COG0392	lysyltransferase activity
ET464_RS16115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ET464_RS16125	COG2207	Transcriptional regulator
ET464_RS16125	COG1917	Cupin 2, conserved barrel domain protein
ET464_RS16130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET464_RS16150	COG1132	(ABC) transporter
ET464_RS16165	COG0656	L-ascorbic acid biosynthetic process
ET464_RS16175	COG3118	belongs to the thioredoxin family
ET464_RS16185	COG1605	Chorismate mutase
ET464_RS16185	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ET464_RS16190	COG0012	GTP binding
ET464_RS16195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ET464_RS16200	COG2890	protein-(glutamine-N5) methyltransferase activity
ET464_RS16210	COG0009	L-threonylcarbamoyladenylate synthase
ET464_RS16215	COG1971	Probably functions as a manganese efflux pump
ET464_RS16235	COG4166	transmembrane transport
ET464_RS16240	COG0601	transmembrane transport
ET464_RS16245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET464_RS16250	COG0444	Belongs to the ABC transporter superfamily
ET464_RS16255	COG4608	Belongs to the ABC transporter superfamily
ET464_RS16265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ET464_RS16280	COG0356	it plays a direct role in the translocation of protons across the membrane
ET464_RS16285	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ET464_RS16290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ET464_RS16300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ET464_RS16305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ET464_RS16310	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ET464_RS16315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ET464_RS16325	COG0840	transmembrane signaling receptor activity
ET464_RS16335	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ET464_RS16340	COG1007	ATP synthesis coupled electron transport
ET464_RS16360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ET464_RS16375	COG2385	sporulation resulting in formation of a cellular spore
ET464_RS16385	COG1609	Transcriptional regulator
ET464_RS16395	COG4786	Flagellar basal body rod
ET464_RS16400	COG4786	Flagellar basal body rod
ET464_RS16410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ET464_RS16415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ET464_RS16420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ET464_RS16440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ET464_RS16445	COG0860	N-Acetylmuramoyl-L-alanine amidase
ET464_RS16450	COG2911	Protein conserved in bacteria
ET464_RS16450	COG3266	domain, Protein
ET464_RS16450	COG1361	Conserved repeat domain
ET464_RS16470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ET464_RS16505	COG1272	protein, Hemolysin III
ET464_RS16515	COG1040	competence protein
ET464_RS16525	COG2747	anti-sigma28 factor FlgM
ET464_RS16535	COG1256	bacterial-type flagellum assembly
ET464_RS16535	COG4786	Flagellar basal body rod
ET464_RS16540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET464_RS16550	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ET464_RS16555	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ET464_RS16560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET464_RS16570	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ET464_RS16575	COG1516	flagellar protein fliS
ET464_RS16595	COG1086	Polysaccharide biosynthesis protein
ET464_RS16600	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
ET464_RS16615	COG1073	alpha beta
ET464_RS16615	COG2226	methyltransferase
ET464_RS16620	COG2226	methyltransferase
ET464_RS16625	COG2089	acid synthase
ET464_RS16630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ET464_RS16635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ET464_RS16640	COG0457	Tetratricopeptide repeat
ET464_RS16640	COG0463	Glycosyl transferase, family 2
ET464_RS16645	COG0438	transferase activity, transferring glycosyl groups
ET464_RS16650	COG1278	Cold shock
ET464_RS16660	COG3944	biosynthesis protein
ET464_RS16665	COG0489	protein tyrosine kinase activity
ET464_RS16680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ET464_RS16685	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ET464_RS16695	COG1215	transferase activity, transferring glycosyl groups
ET464_RS16725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ET464_RS16750	COG0653	protein targeting
ET464_RS16760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ET464_RS16765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ET464_RS16770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ET464_RS16780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ET464_RS16785	COG0137	argininosuccinate synthase activity
ET464_RS16790	COG0165	Argininosuccinate lyase
ET464_RS16800	COG2720	vancomycin resistance protein
ET464_RS16805	COG2884	Cell division ATP-binding protein ftsE
ET464_RS16810	COG2177	Part of the ABC transporter FtsEX involved in
ET464_RS16815	COG0739	heme binding
ET464_RS16820	COG3409	Peptidoglycan-binding domain 1 protein
ET464_RS16820	COG0793	Belongs to the peptidase S41A family
ET464_RS16835	COG0556	nucleotide-excision repair
ET464_RS16845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ET464_RS16855	COG1082	Xylose isomerase domain protein TIM barrel
ET464_RS16865	COG0826	peptidase U32
ET464_RS16870	COG1595	DNA-templated transcription, initiation
ET464_RS16885	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ET464_RS16895	COG1132	(ABC) transporter
ET464_RS16900	COG2188	Transcriptional regulator
ET464_RS16905	COG1131	(ABC) transporter
ET464_RS16915	COG1968	undecaprenyl-diphosphatase activity
ET464_RS16920	COG0210	DNA helicase
ET464_RS16925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ET464_RS16955	COG3880	PFAM UvrB UvrC protein
ET464_RS16960	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ET464_RS16965	COG0542	response to heat
ET464_RS16970	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ET464_RS16975	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ET464_RS16980	COG1183	phosphatidylcholine synthase activity
ET464_RS16990	COG4956	integral membrane protein (PIN domain superfamily)
ET464_RS16995	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ET464_RS17000	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ET464_RS17005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ET464_RS17015	COG1045	serine acetyltransferase
ET464_RS17020	COG0215	cysteine-tRNA ligase activity
ET464_RS17025	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ET464_RS17030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ET464_RS17035	COG3688	RNA-binding protein containing a PIN domain
ET464_RS17045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ET464_RS17050	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ET464_RS17055	COG0250	Participates in transcription elongation, termination and antitermination
ET464_RS17065	COG0081	regulation of translation
ET464_RS17075	COG0222	ribosome binding
ET464_RS17080	COG2813	Specifically methylates the guanine in position
ET464_RS17085	COG0085	RNA polymerase activity
ET464_RS17090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ET464_RS17095	COG1358	cellular component organization or biogenesis
ET464_RS17100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ET464_RS17105	COG0049	tRNA binding
ET464_RS17110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ET464_RS17115	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ET464_RS17125	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ET464_RS17130	COG0088	Forms part of the polypeptide exit tunnel
ET464_RS17135	COG0089	rRNA binding
ET464_RS17140	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ET464_RS17145	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ET464_RS17155	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ET464_RS17160	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ET464_RS17165	COG0255	Belongs to the universal ribosomal protein uL29 family
ET464_RS17170	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ET464_RS17175	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ET464_RS17180	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ET464_RS17185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ET464_RS17190	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ET464_RS17195	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ET464_RS17200	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ET464_RS17205	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ET464_RS17210	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ET464_RS17215	COG1841	ribosomal large subunit assembly
ET464_RS17220	COG0200	Binds to the 23S rRNA
ET464_RS17225	COG0201	protein transport
ET464_RS17230	COG0563	adenylate kinase activity
ET464_RS17235	COG0024	Methionine aminopeptidase
ET464_RS17240	COG2163	COG2163 Ribosomal protein L14E L6E L27E
ET464_RS17245	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ET464_RS17250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ET464_RS17255	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ET464_RS17260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ET464_RS17265	COG0202	RNA polymerase activity
ET464_RS17270	COG0203	ribosomal protein L17
ET464_RS17275	COG0101	tRNA pseudouridine synthase activity
ET464_RS17280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ET464_RS17285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ET464_RS17290	COG0175	sulfate reduction
ET464_RS17300	COG0860	N-Acetylmuramoyl-L-alanine amidase
ET464_RS17305	COG0489	protein tyrosine kinase activity
ET464_RS17320	COG0726	polysaccharide deacetylase
ET464_RS17395	COG2814	Major facilitator Superfamily
ET464_RS17400	COG0778	Nitroreductase
ET464_RS17405	COG1120	ATPase activity
ET464_RS17430	COG2814	Major facilitator Superfamily
ET464_RS17440	COG0655	NAD(P)H dehydrogenase (quinone) activity
ET464_RS17445	COG1566	PFAM secretion protein HlyD family protein
ET464_RS17450	COG2814	Major facilitator Superfamily
ET464_RS17455	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ET464_RS17460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET464_RS17465	COG1595	DNA-templated transcription, initiation
ET464_RS17470	COG5662	AntiSigma factor
ET464_RS17475	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ET464_RS17485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ET464_RS17515	COG1846	Transcriptional regulator
ET464_RS17525	COG2211	Major facilitator Superfamily
ET464_RS17540	COG4208	sulfate ABC transporter
ET464_RS17545	COG3833	ABC-type maltose transport systems, permease component
ET464_RS17555	COG2030	dehydratase
ET464_RS17560	COG3401	FG-GAP repeat protein
ET464_RS17565	COG2226	methyltransferase
ET464_RS17590	COG0673	inositol 2-dehydrogenase activity
ET464_RS17595	COG4977	sequence-specific DNA binding
ET464_RS17595	COG1917	Cupin 2, conserved barrel domain protein
ET464_RS17600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET464_RS17620	COG0673	inositol 2-dehydrogenase activity
ET464_RS17625	COG2207	Transcriptional regulator
ET464_RS17625	COG0662	Cupin 2, conserved barrel domain protein
ET464_RS17630	COG1653	transport
ET464_RS17635	COG4209	transmembrane transport
ET464_RS17640	COG0395	ABC-type sugar transport system, permease component
ET464_RS17655	COG4209	transmembrane transport
ET464_RS17660	COG0395	ABC-type sugar transport system, permease component
ET464_RS17665	COG1653	transport
ET464_RS17670	COG0673	inositol 2-dehydrogenase activity
ET464_RS17675	COG0425	Belongs to the sulfur carrier protein TusA family
ET464_RS17680	COG2391	methyltransferase activity
ET464_RS17685	COG1846	Transcriptional regulator
ET464_RS17690	COG2814	Major facilitator Superfamily
ET464_RS17695	COG2267	carboxylic ester hydrolase activity
ET464_RS17710	COG0444	Belongs to the ABC transporter superfamily
ET464_RS17715	COG4608	Belongs to the ABC transporter superfamily
ET464_RS17720	COG0601	transmembrane transport
ET464_RS17725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET464_RS17730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ET464_RS17740	COG1175	transmembrane transport
ET464_RS17745	COG0395	ABC-type sugar transport system, permease component
ET464_RS17755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET464_RS17770	COG3639	organic phosphonate transmembrane transporter activity
ET464_RS17780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ET464_RS17785	COG0737	Belongs to the 5'-nucleotidase family
ET464_RS17795	COG1120	ATPase activity
ET464_RS17800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET464_RS17805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET464_RS17810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET464_RS17815	COG1801	Protein of unknown function DUF72
ET464_RS17825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ET464_RS17830	COG1368	sulfuric ester hydrolase activity
ET464_RS17855	COG1175	transmembrane transport
ET464_RS17865	COG2972	Histidine kinase
ET464_RS17870	COG2207	Transcriptional regulator
ET464_RS17875	COG1368	sulfuric ester hydrolase activity
ET464_RS17880	COG2972	Histidine kinase
ET464_RS17890	COG1175	transmembrane transport
ET464_RS17895	COG0395	ABC-type sugar transport system, permease component
ET464_RS17910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ET464_RS17915	COG5566	PFAM Mor transcription activator
ET464_RS17920	COG4585	Histidine kinase
ET464_RS17920	COG2203	Gaf domain
ET464_RS17925	COG2197	response regulator
ET464_RS17930	COG0431	NADPH-dependent FMN reductase
ET464_RS17935	COG0824	Thioesterase
ET464_RS17940	COG0583	DNA-binding transcription factor activity
ET464_RS17950	COG2226	methyltransferase
ET464_RS17960	COG0018	arginyl-trna synthetase
ET464_RS17980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ET464_RS17985	COG0432	Pfam Uncharacterised protein family UPF0047
ET464_RS18000	COG2972	Histidine kinase
ET464_RS18005	COG4753	response regulator
ET464_RS18005	COG2207	Transcriptional regulator
ET464_RS18010	COG1175	transmembrane transport
ET464_RS18115	COG1175	transmembrane transport
ET464_RS18120	COG0395	ABC-type sugar transport system, permease component
ET464_RS18135	COG2207	Transcriptional regulator
ET464_RS18165	COG0667	Aldo Keto reductase
ET464_RS18170	COG4753	response regulator
ET464_RS18170	COG2207	Transcriptional regulator
ET464_RS18175	COG2972	Histidine kinase
ET464_RS18180	COG1653	transport
ET464_RS18185	COG1175	transmembrane transport
ET464_RS18190	COG0395	ABC-type sugar transport system, permease component
ET464_RS18195	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ET464_RS18200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ET464_RS18210	COG0686	Belongs to the AlaDH PNT family
ET464_RS18215	COG3733	amine oxidase
ET464_RS18225	COG3275	phosphorelay sensor kinase activity
ET464_RS18235	COG1653	transport
ET464_RS18240	COG4209	transmembrane transport
ET464_RS18245	COG0395	ABC-type sugar transport system, permease component
ET464_RS18295	COG2309	aminopeptidase activity
ET464_RS18305	COG2814	Major facilitator Superfamily
ET464_RS18310	COG3858	chitin binding
ET464_RS18315	COG1405	negative regulation of cell septum assembly
ET464_RS18315	COG3012	SEC-C Motif Domain Protein
ET464_RS18335	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ET464_RS18340	COG0783	Belongs to the Dps family
ET464_RS18345	COG2205	protein histidine kinase activity
ET464_RS18365	COG1028	Short-chain dehydrogenase reductase Sdr
ET464_RS18370	COG1902	pentaerythritol trinitrate reductase activity
ET464_RS18380	COG0584	glycerophosphoryl diester phosphodiesterase
ET464_RS18390	COG2608	mercury ion transmembrane transporter activity
ET464_RS18395	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ET464_RS18405	COG3534	alpha-L-arabinofuranosidase
ET464_RS18410	COG2323	membrane
ET464_RS18435	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ET464_RS18440	COG3336	cytochrome c oxidase
ET464_RS18455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ET464_RS18465	COG4152	abc transporter atp-binding protein
ET464_RS18470	COG1668	transmembrane transport
ET464_RS18485	COG2207	Transcriptional regulator
ET464_RS18495	COG1960	acyl-CoA dehydrogenase activity
ET464_RS18505	COG1846	Transcriptional regulator
ET464_RS18510	COG0346	lactoylglutathione lyase activity
ET464_RS18515	COG0400	carboxylic ester hydrolase activity
ET464_RS18520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ET464_RS18525	COG0805	protein transport
ET464_RS18540	COG2017	converts alpha-aldose to the beta-anomer
ET464_RS18550	COG2706	6-phosphogluconolactonase activity
ET464_RS18555	COG2223	nitrite transmembrane transporter activity
ET464_RS18575	COG1361	Conserved repeat domain
ET464_RS18595	COG1253	flavin adenine dinucleotide binding
ET464_RS18605	COG1940	carbohydrate kinase activity
ET464_RS18615	COG1070	Carbohydrate kinase
ET464_RS18620	COG1846	Transcriptional regulator
ET464_RS18630	COG0840	transmembrane signaling receptor activity
ET464_RS18650	COG2081	HI0933 family
ET464_RS18655	COG2267	carboxylic ester hydrolase activity
ET464_RS18660	COG5002	protein histidine kinase activity
ET464_RS18680	COG2217	Heavy metal translocating P-type atpase
ET464_RS18695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ET464_RS18700	COG2010	Cytochrome c
ET464_RS18715	COG0800	Aldolase
ET464_RS18735	COG2801	Transposase and inactivated derivatives
ET464_RS18750	COG1175	transmembrane transport
ET464_RS18755	COG0395	ABC-type sugar transport system, permease component
ET464_RS18760	COG0366	Alpha amylase catalytic
ET464_RS18770	COG3655	Transcriptional regulator
ET464_RS18780	COG2814	Major facilitator Superfamily
ET464_RS18785	COG1309	transcriptional regulator
ET464_RS18790	COG1472	Belongs to the glycosyl hydrolase 3 family
ET464_RS18810	COG0395	ABC-type sugar transport system, permease component
ET464_RS18815	COG0383	alpha-mannosidase activity
ET464_RS18820	COG4948	Mandelate Racemase Muconate Lactonizing
ET464_RS18830	COG4989	oxidoreductase activity
ET464_RS18840	COG1725	Transcriptional regulator
ET464_RS18860	COG4129	membrane
ET464_RS18875	COG1413	lyase activity
ET464_RS18885	COG0673	inositol 2-dehydrogenase activity
ET464_RS18890	COG0488	(ABC) transporter
ET464_RS18900	COG4533	DNA binding
ET464_RS18905	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ET464_RS18925	COG1309	transcriptional regulator
ET464_RS18930	COG1511	domain protein
ET464_RS18945	COG0070	glutamate synthase
ET464_RS18945	COG0067	glutamate synthase
ET464_RS18945	COG0069	glutamate synthase activity
ET464_RS18950	COG1396	sequence-specific DNA binding
ET464_RS18960	COG0489	protein tyrosine kinase activity
ET464_RS18970	COG1316	TRANSCRIPTIONal
ET464_RS18980	COG1131	(ABC) transporter
ET464_RS18985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ET464_RS18995	COG0739	heme binding
ET464_RS18995	COG1196	nuclear chromosome segregation
ET464_RS18995	COG0741	lytic transglycosylase activity
ET464_RS19000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ET464_RS19015	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ET464_RS19035	COG0586	Pfam SNARE associated Golgi protein
ET464_RS19050	COG2183	response to ionizing radiation
ET464_RS19060	COG0778	Nitroreductase
ET464_RS19075	COG3091	SprT-like family
ET464_RS19105	COG2169	Transcriptional regulator
ET464_RS19120	COG0572	uridine kinase
ET464_RS19125	COG0024	Methionine aminopeptidase
ET464_RS19130	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ET464_RS19135	COG2153	protein acetylation
ET464_RS19140	COG0673	inositol 2-dehydrogenase activity
ET464_RS19155	COG2207	Transcriptional regulator
ET464_RS19180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ET464_RS19185	COG1522	sequence-specific DNA binding
ET464_RS19190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ET464_RS19220	COG0673	inositol 2-dehydrogenase activity
ET464_RS19225	COG2340	Cysteine-rich secretory protein family
ET464_RS19230	COG3584	3D domain protein
ET464_RS19230	COG1388	LysM domain
ET464_RS19240	COG0840	transmembrane signaling receptor activity
ET464_RS19255	COG0180	Tryptophanyl-tRNA synthetase
ET464_RS19270	COG1988	membrane-bound metal-dependent
ET464_RS19285	COG3773	Cell wall hydrolase
ET464_RS19305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ET464_RS19335	COG0561	phosphatase activity
ET464_RS19340	COG2839	Protein conserved in bacteria
ET464_RS19345	COG2244	polysaccharide biosynthetic process
ET464_RS19350	COG0454	-acetyltransferase
ET464_RS19360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ET464_RS19365	COG1612	heme a metabolic process
ET464_RS19370	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ET464_RS19380	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ET464_RS19385	COG4844	belongs to the
ET464_RS19390	COG1252	NADH dehydrogenase
ET464_RS19395	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ET464_RS19400	COG0316	Belongs to the HesB IscA family
ET464_RS19435	COG1408	metallophosphoesterase
ET464_RS19445	COG0189	ligase activity
ET464_RS19465	COG1252	NADH dehydrogenase
ET464_RS19475	COG4191	Histidine kinase
ET464_RS19495	COG1484	DNA-dependent DNA replication
ET464_RS19505	COG0601	transmembrane transport
ET464_RS19510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET464_RS19515	COG0444	Belongs to the ABC transporter superfamily
ET464_RS19520	COG4608	Belongs to the ABC transporter superfamily
ET464_RS19525	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ET464_RS19530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ET464_RS19535	COG4208	sulfate ABC transporter
ET464_RS19550	COG0322	excinuclease ABC activity
ET464_RS19560	COG0569	domain protein
ET464_RS19565	COG0583	DNA-binding transcription factor activity
ET464_RS19570	COG2009	succinate dehydrogenase
ET464_RS19575	COG1053	succinate dehydrogenase
ET464_RS19580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ET464_RS19585	COG1733	regulation of RNA biosynthetic process
ET464_RS19595	COG0583	DNA-binding transcription factor activity
ET464_RS19600	COG0598	Magnesium transport protein CorA
ET464_RS19605	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ET464_RS19610	COG0626	cystathionine gamma-synthase activity
ET464_RS19615	COG0626	cystathionine gamma-synthase activity
ET464_RS19625	COG2972	Histidine kinase
ET464_RS19630	COG2207	Transcriptional regulator
ET464_RS19630	COG4753	response regulator
ET464_RS19635	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ET464_RS19645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ET464_RS19650	COG3584	3D domain protein
ET464_RS19910	COG1136	(ABC) transporter
ET464_RS19910	COG0577	efflux transmembrane transporter activity