locus-tag	class	description
GE073_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GE073_RS00010	COG0592	DNA-directed DNA polymerase activity
GE073_RS00015	COG2501	S4 domain
GE073_RS00030	COG0187	DNA topoisomerase II activity
GE073_RS00035	COG0189	ligase activity
GE073_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GE073_RS00045	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GE073_RS00080	COG1982	Orn Lys Arg decarboxylase major
GE073_RS00085	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GE073_RS00090	COG3870	Protein conserved in bacteria
GE073_RS00095	COG1728	Protein conserved in bacteria
GE073_RS00100	COG0470	DNA polymerase III
GE073_RS00105	COG1774	PSP1 C-terminal conserved region
GE073_RS00110	COG4467	Involved in initiation control of chromosome replication
GE073_RS00115	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GE073_RS00120	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GE073_RS00125	COG2002	toxin-antitoxin pair type II binding
GE073_RS00130	COG1078	dGTPase activity
GE073_RS00135	COG0084	hydrolase, TatD family'
GE073_RS00140	COG3584	3D domain protein
GE073_RS00140	COG3583	domain protein
GE073_RS00145	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GE073_RS00150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GE073_RS00160	COG4466	Protein conserved in bacteria
GE073_RS00170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GE073_RS00175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GE073_RS00180	COG0251	oxidation-reduction process
GE073_RS00185	COG2088	sporulation resulting in formation of a cellular spore
GE073_RS00190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GE073_RS00195	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GE073_RS00200	COG0193	aminoacyl-tRNA hydrolase activity
GE073_RS00210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GE073_RS00215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GE073_RS00225	COG1172	Belongs to the binding-protein-dependent transport system permease family
GE073_RS00235	COG0411	ABC transporter
GE073_RS00250	COG2002	toxin-antitoxin pair type II binding
GE073_RS00260	COG2244	polysaccharide biosynthetic process
GE073_RS00265	COG3956	TIGRFAM MazG family protein
GE073_RS00275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GE073_RS00295	COG1098	S1 RNA binding domain
GE073_RS00320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GE073_RS00330	COG1459	type II secretion system
GE073_RS00340	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GE073_RS00360	COG2208	phosphoserine phosphatase activity
GE073_RS00370	COG0737	Belongs to the 5'-nucleotidase family
GE073_RS00395	COG1902	pentaerythritol trinitrate reductase activity
GE073_RS00405	COG2815	serine threonine protein kinase
GE073_RS00405	COG0515	serine threonine protein kinase
GE073_RS00410	COG0037	tRNA processing
GE073_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GE073_RS00425	COG1744	ABC transporter substrate-binding protein PnrA-like
GE073_RS00430	COG3845	ABC transporter
GE073_RS00435	COG4603	Belongs to the binding-protein-dependent transport system permease family
GE073_RS00440	COG1079	Belongs to the binding-protein-dependent transport system permease family
GE073_RS00445	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GE073_RS00450	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GE073_RS00460	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GE073_RS00465	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GE073_RS00470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GE073_RS00475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE073_RS00480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GE073_RS00485	COG0512	Glutamine amidotransferase of anthranilate synthase
GE073_RS00490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE073_RS00495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GE073_RS00500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GE073_RS00505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GE073_RS00510	COG1396	sequence-specific DNA binding
GE073_RS00515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GE073_RS00520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GE073_RS00525	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GE073_RS00560	COG0517	IMP dehydrogenase activity
GE073_RS00560	COG0516	GMP reductase activity
GE073_RS00580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GE073_RS00625	COG0488	(ABC) transporter
GE073_RS00660	COG0590	tRNA wobble adenosine to inosine editing
GE073_RS00665	COG4191	Histidine kinase
GE073_RS00670	COG1187	pseudouridine synthase activity
GE073_RS00675	COG1360	Flagellar Motor Protein
GE073_RS00680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GE073_RS00705	COG4977	sequence-specific DNA binding
GE073_RS00705	COG1917	Cupin 2, conserved barrel domain protein
GE073_RS00720	COG2207	Transcriptional regulator
GE073_RS00730	COG3708	Transcriptional regulator
GE073_RS00730	COG2207	Transcriptional regulator
GE073_RS00745	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GE073_RS00750	COG1846	Transcriptional regulator
GE073_RS00765	COG0450	alkyl hydroperoxide reductase
GE073_RS00770	COG0583	DNA-binding transcription factor activity
GE073_RS00775	COG2610	gluconate transmembrane transporter activity
GE073_RS00780	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS00785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GE073_RS00790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GE073_RS00830	COG2133	pyrroloquinoline quinone binding
GE073_RS00855	COG0861	Integral membrane protein TerC family
GE073_RS00860	COG1131	(ABC) transporter
GE073_RS00890	COG0601	transmembrane transport
GE073_RS00895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE073_RS00925	COG1486	melibiose metabolic process
GE073_RS00930	COG1737	Transcriptional regulator
GE073_RS00945	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GE073_RS00955	COG1175	transmembrane transport
GE073_RS00960	COG0395	ABC-type sugar transport system, permease component
GE073_RS00970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GE073_RS00975	COG3876	Protein conserved in bacteria
GE073_RS00985	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GE073_RS00990	COG4191	Histidine kinase
GE073_RS01005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS01010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS01015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS01045	COG2207	Transcriptional regulator
GE073_RS01050	COG2176	DNA-directed DNA polymerase activity
GE073_RS01055	COG0708	Exodeoxyribonuclease III
GE073_RS01065	COG1136	(ABC) transporter
GE073_RS01080	COG1876	peptidase activity
GE073_RS01085	COG0415	Belongs to the DNA photolyase family
GE073_RS01090	COG0791	NLP P60 protein
GE073_RS01120	COG1649	PFAM Uncharacterised BCR, COG1649
GE073_RS01145	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GE073_RS01155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE073_RS01160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GE073_RS01165	COG0010	Belongs to the arginase family
GE073_RS01185	COG0018	arginyl-trna synthetase
GE073_RS01190	COG1404	Belongs to the peptidase S8 family
GE073_RS01195	COG3343	RNA polymerase activity
GE073_RS01200	COG0504	CTP synthase activity
GE073_RS01210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GE073_RS01225	COG0254	rRNA binding
GE073_RS01240	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GE073_RS01245	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GE073_RS01250	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GE073_RS01310	COG2508	Transcriptional regulator
GE073_RS01315	COG3842	ATPase activity
GE073_RS01320	COG1472	Belongs to the glycosyl hydrolase 3 family
GE073_RS01325	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GE073_RS01330	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GE073_RS01335	COG0546	phosphoglycolate phosphatase activity
GE073_RS01340	COG0110	maltose O-acetyltransferase activity
GE073_RS01345	COG0726	polysaccharide deacetylase
GE073_RS01345	COG1649	PFAM Uncharacterised BCR, COG1649
GE073_RS01350	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GE073_RS01355	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GE073_RS01360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GE073_RS01365	COG0131	Imidazoleglycerol-phosphate dehydratase
GE073_RS01370	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GE073_RS01375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GE073_RS01380	COG0107	imidazoleglycerol-phosphate synthase activity
GE073_RS01385	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GE073_RS01385	COG0140	phosphoribosyl-ATP diphosphatase activity
GE073_RS01390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GE073_RS01395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GE073_RS01405	COG3118	belongs to the thioredoxin family
GE073_RS01405	COG0492	ferredoxin-NADP+ reductase activity
GE073_RS01410	COG1940	carbohydrate kinase activity
GE073_RS01415	COG1660	Displays ATPase and GTPase activities
GE073_RS01420	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GE073_RS01425	COG1481	regulation of sporulation
GE073_RS01430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE073_RS01440	COG0740	serine-type endopeptidase activity
GE073_RS01455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GE073_RS01465	COG0149	triose-phosphate isomerase activity
GE073_RS01475	COG0148	phosphopyruvate hydratase activity
GE073_RS01485	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GE073_RS01490	COG0557	exoribonuclease II activity
GE073_RS01500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GE073_RS01515	COG3654	unkown
GE073_RS01540	COG4209	transmembrane transport
GE073_RS01545	COG0395	ABC-type sugar transport system, permease component
GE073_RS01550	COG1733	regulation of RNA biosynthetic process
GE073_RS01555	COG2249	NAD(P)H dehydrogenase (quinone) activity
GE073_RS01585	COG1388	LysM domain
GE073_RS01600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GE073_RS01610	COG4152	abc transporter atp-binding protein
GE073_RS01620	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS01625	COG2226	methyltransferase
GE073_RS01650	COG0142	geranyltranstransferase activity
GE073_RS01660	COG4585	Histidine kinase
GE073_RS01665	COG2197	response regulator
GE073_RS01670	COG1278	Cold shock
GE073_RS01690	COG0456	acetyltransferase
GE073_RS01695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE073_RS01700	COG0765	amino acid transport
GE073_RS01705	COG0765	amino acid transport
GE073_RS01710	COG1126	abc transporter atp-binding protein
GE073_RS01715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE073_RS01720	COG1473	amidohydrolase
GE073_RS01730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE073_RS01740	COG4720	Psort location CytoplasmicMembrane, score
GE073_RS01750	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GE073_RS01755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GE073_RS01775	COG2226	methyltransferase
GE073_RS01780	COG2322	membrane
GE073_RS01790	COG0745	RESPONSE REGULATOR receiver
GE073_RS01795	COG5002	protein histidine kinase activity
GE073_RS01820	COG4124	Belongs to the glycosyl hydrolase 26 family
GE073_RS01830	COG1278	Cold shock
GE073_RS01840	COG1122	ATPase activity
GE073_RS01850	COG0667	Aldo Keto reductase
GE073_RS01880	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GE073_RS01905	COG1309	transcriptional regulator
GE073_RS01925	COG5002	protein histidine kinase activity
GE073_RS01935	COG3402	PFAM membrane-flanked domain
GE073_RS01950	COG4533	DNA binding
GE073_RS01980	COG0246	Mannitol dehydrogenase
GE073_RS01985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GE073_RS01995	COG0735	belongs to the Fur family
GE073_RS02015	COG4149	molybdate abc transporter
GE073_RS02020	COG0725	ABC transporter, periplasmic molybdate-binding protein
GE073_RS02030	COG1910	domain protein
GE073_RS02035	COG2814	Major facilitator Superfamily
GE073_RS02050	COG2340	Cysteine-rich secretory protein family
GE073_RS02055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GE073_RS02060	COG0745	RESPONSE REGULATOR receiver
GE073_RS02065	COG0642	Histidine kinase
GE073_RS02095	COG2226	methyltransferase
GE073_RS02105	COG4129	membrane
GE073_RS02110	COG1361	Conserved repeat domain
GE073_RS02110	COG2911	Protein conserved in bacteria
GE073_RS02110	COG3266	domain, Protein
GE073_RS02115	COG0583	DNA-binding transcription factor activity
GE073_RS02120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE073_RS02165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GE073_RS02175	COG2076	Multidrug Resistance protein
GE073_RS02180	COG2076	Multidrug Resistance protein
GE073_RS02200	COG0740	serine-type endopeptidase activity
GE073_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS02215	COG1760	l-serine dehydratase
GE073_RS02220	COG1760	l-serine dehydratase
GE073_RS02230	COG1175	transmembrane transport
GE073_RS02235	COG0395	ABC-type sugar transport system, permease component
GE073_RS02245	COG1132	(ABC) transporter
GE073_RS02260	COG0346	lactoylglutathione lyase activity
GE073_RS02275	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GE073_RS02280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GE073_RS02285	COG2207	Transcriptional regulator
GE073_RS02285	COG4753	response regulator
GE073_RS02290	COG4209	transmembrane transport
GE073_RS02295	COG0395	ABC-type sugar transport system, permease component
GE073_RS02300	COG1653	transport
GE073_RS02320	COG2182	Extracellular solute-binding protein
GE073_RS02325	COG1175	transmembrane transport
GE073_RS02330	COG3833	ABC-type maltose transport systems, permease component
GE073_RS02335	COG2972	Histidine kinase
GE073_RS02340	COG4753	response regulator
GE073_RS02340	COG2207	Transcriptional regulator
GE073_RS02345	COG4166	transmembrane transport
GE073_RS02350	COG0601	transmembrane transport
GE073_RS02355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE073_RS02360	COG0444	Belongs to the ABC transporter superfamily
GE073_RS02365	COG4608	Belongs to the ABC transporter superfamily
GE073_RS02375	COG3458	cephalosporin-C deacetylase activity
GE073_RS02400	COG1842	Phage shock protein A
GE073_RS02415	COG0210	DNA helicase
GE073_RS02420	COG1846	Transcriptional regulator
GE073_RS02425	COG0778	Nitroreductase
GE073_RS02430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GE073_RS02440	COG0534	Mate efflux family protein
GE073_RS02445	COG0383	alpha-mannosidase activity
GE073_RS02455	COG0395	ABC-type sugar transport system, permease component
GE073_RS02460	COG4209	transmembrane transport
GE073_RS02470	COG4753	response regulator
GE073_RS02470	COG2207	Transcriptional regulator
GE073_RS02475	COG2972	Histidine kinase
GE073_RS02485	COG0720	synthase
GE073_RS02505	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GE073_RS02510	COG0833	amino acid
GE073_RS02515	COG1404	Belongs to the peptidase S8 family
GE073_RS02520	COG1404	Belongs to the peptidase S8 family
GE073_RS02535	COG2378	regulation of single-species biofilm formation
GE073_RS02540	COG2318	DinB family
GE073_RS02550	COG0673	inositol 2-dehydrogenase activity
GE073_RS02555	COG0673	inositol 2-dehydrogenase activity
GE073_RS02565	COG0604	alcohol dehydrogenase
GE073_RS02570	COG1247	-acetyltransferase
GE073_RS02575	COG1929	Belongs to the glycerate kinase type-1 family
GE073_RS02585	COG0840	transmembrane signaling receptor activity
GE073_RS02590	COG2326	polyphosphate kinase activity
GE073_RS02595	COG2357	RelA SpoT domain protein
GE073_RS02605	COG1368	sulfuric ester hydrolase activity
GE073_RS02610	COG1595	DNA-templated transcription, initiation
GE073_RS02620	COG1131	(ABC) transporter
GE073_RS02635	COG1368	sulfuric ester hydrolase activity
GE073_RS02655	COG0018	arginyl-trna synthetase
GE073_RS02660	COG1653	transport
GE073_RS02670	COG4209	transmembrane transport
GE073_RS02675	COG0395	ABC-type sugar transport system, permease component
GE073_RS02685	COG2207	Transcriptional regulator
GE073_RS02690	COG0277	FAD linked oxidase domain protein
GE073_RS02695	COG2272	Belongs to the type-B carboxylesterase lipase family
GE073_RS02700	COG0745	RESPONSE REGULATOR receiver
GE073_RS02705	COG2205	protein histidine kinase activity
GE073_RS02710	COG1131	(ABC) transporter
GE073_RS02720	COG1360	Flagellar Motor Protein
GE073_RS02730	COG0556	nucleotide-excision repair
GE073_RS02740	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GE073_RS02755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GE073_RS02770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GE073_RS02775	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS02780	COG1312	Catalyzes the dehydration of D-mannonate
GE073_RS02790	COG0826	peptidase U32
GE073_RS02810	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GE073_RS02815	COG0210	DNA helicase
GE073_RS02820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GE073_RS02845	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GE073_RS02860	COG3880	PFAM UvrB UvrC protein
GE073_RS02865	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GE073_RS02870	COG0542	response to heat
GE073_RS02890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE073_RS02895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE073_RS02915	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GE073_RS02920	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GE073_RS02925	COG1183	phosphatidylcholine synthase activity
GE073_RS02935	COG4956	integral membrane protein (PIN domain superfamily)
GE073_RS02940	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GE073_RS02945	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GE073_RS02950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GE073_RS02955	COG1045	serine acetyltransferase
GE073_RS02960	COG0215	cysteine-tRNA ligase activity
GE073_RS02965	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GE073_RS02970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GE073_RS02975	COG3688	RNA-binding protein containing a PIN domain
GE073_RS02990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GE073_RS02995	COG0250	Participates in transcription elongation, termination and antitermination
GE073_RS03000	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GE073_RS03005	COG0081	regulation of translation
GE073_RS03015	COG0222	ribosome binding
GE073_RS03020	COG2813	Specifically methylates the guanine in position
GE073_RS03025	COG0085	RNA polymerase activity
GE073_RS03030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GE073_RS03035	COG1358	cellular component organization or biogenesis
GE073_RS03040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GE073_RS03045	COG0049	tRNA binding
GE073_RS03050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GE073_RS03055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GE073_RS03065	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GE073_RS03070	COG0088	Forms part of the polypeptide exit tunnel
GE073_RS03075	COG0089	rRNA binding
GE073_RS03080	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GE073_RS03085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GE073_RS03095	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GE073_RS03100	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GE073_RS03105	COG0255	Belongs to the universal ribosomal protein uL29 family
GE073_RS03110	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GE073_RS03115	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GE073_RS03120	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GE073_RS03125	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GE073_RS03130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GE073_RS03135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GE073_RS03140	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GE073_RS03145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GE073_RS03150	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GE073_RS03155	COG1841	ribosomal large subunit assembly
GE073_RS03160	COG0200	Binds to the 23S rRNA
GE073_RS03165	COG0201	protein transport
GE073_RS03170	COG0563	adenylate kinase activity
GE073_RS03175	COG0024	Methionine aminopeptidase
GE073_RS03185	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GE073_RS03190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GE073_RS03195	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GE073_RS03200	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GE073_RS03205	COG0202	RNA polymerase activity
GE073_RS03210	COG0203	ribosomal protein L17
GE073_RS03215	COG0101	tRNA pseudouridine synthase activity
GE073_RS03220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GE073_RS03225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GE073_RS03235	COG0175	sulfate reduction
GE073_RS03245	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE073_RS03250	COG0489	protein tyrosine kinase activity
GE073_RS03265	COG0726	polysaccharide deacetylase
GE073_RS03335	COG1120	ATPase activity
GE073_RS03365	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GE073_RS03370	COG1595	DNA-templated transcription, initiation
GE073_RS03375	COG5662	AntiSigma factor
GE073_RS03380	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GE073_RS03390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GE073_RS03410	COG1349	DNA-binding transcription factor activity
GE073_RS03430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE073_RS03435	COG0402	S-adenosylhomocysteine deaminase activity
GE073_RS03445	COG0402	S-adenosylhomocysteine deaminase activity
GE073_RS03450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE073_RS03455	COG2207	Transcriptional regulator
GE073_RS03455	COG4753	response regulator
GE073_RS03460	COG2972	Histidine kinase
GE073_RS03470	COG1175	transmembrane transport
GE073_RS03475	COG0395	ABC-type sugar transport system, permease component
GE073_RS03480	COG3537	Alpha-1,2-mannosidase
GE073_RS03485	COG0583	DNA-binding transcription factor activity
GE073_RS03500	COG0765	amino acid transport
GE073_RS03510	COG3693	PFAM glycoside hydrolase, family 10
GE073_RS03520	COG1653	transport
GE073_RS03525	COG4209	transmembrane transport
GE073_RS03530	COG0395	ABC-type sugar transport system, permease component
GE073_RS03545	COG2972	Histidine kinase
GE073_RS03590	COG3437	response regulator, receiver
GE073_RS03590	COG3850	Histidine kinase
GE073_RS03590	COG4999	Histidine kinase
GE073_RS03590	COG2205	protein histidine kinase activity
GE073_RS03595	COG0784	Response regulator, receiver
GE073_RS03595	COG5002	protein histidine kinase activity
GE073_RS03595	COG2205	protein histidine kinase activity
GE073_RS03615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE073_RS03625	COG0318	PFAM AMP-dependent synthetase and ligase
GE073_RS03645	COG2814	Major facilitator Superfamily
GE073_RS03655	COG2972	Histidine kinase
GE073_RS03660	COG4753	response regulator
GE073_RS03660	COG2207	Transcriptional regulator
GE073_RS03665	COG1653	transport
GE073_RS03670	COG1175	transmembrane transport
GE073_RS03675	COG0395	ABC-type sugar transport system, permease component
GE073_RS03680	COG2755	lipolytic protein G-D-S-L family
GE073_RS03690	COG5002	protein histidine kinase activity
GE073_RS03695	COG2197	response regulator
GE073_RS03715	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GE073_RS03720	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GE073_RS03725	COG1132	(ABC) transporter
GE073_RS03730	COG1132	(ABC) transporter
GE073_RS03750	COG1966	Carbon starvation protein
GE073_RS03760	COG3275	phosphorelay sensor kinase activity
GE073_RS03805	COG2315	Protein conserved in bacteria
GE073_RS03820	COG3275	phosphorelay sensor kinase activity
GE073_RS03830	COG3279	Response regulator of the LytR AlgR family
GE073_RS03840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE073_RS03845	COG0791	NLP P60 protein
GE073_RS03845	COG1388	LysM domain
GE073_RS03845	COG3103	Sh3 type 3 domain protein
GE073_RS03850	COG1846	Transcriptional regulator
GE073_RS03855	COG0346	lactoylglutathione lyase activity
GE073_RS03860	COG0400	carboxylic ester hydrolase activity
GE073_RS03865	COG0346	lactoylglutathione lyase activity
GE073_RS03900	COG1733	regulation of RNA biosynthetic process
GE073_RS03905	COG0604	alcohol dehydrogenase
GE073_RS03920	COG2186	Transcriptional regulator
GE073_RS03925	COG0277	FAD linked oxidase domain protein
GE073_RS03930	COG0247	lactate metabolic process
GE073_RS03940	COG0442	prolyl-tRNA aminoacylation
GE073_RS03960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GE073_RS03970	COG0640	Transcriptional regulator
GE073_RS04050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE073_RS04110	COG1653	transport
GE073_RS04115	COG1175	transmembrane transport
GE073_RS04120	COG0395	ABC-type sugar transport system, permease component
GE073_RS04130	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GE073_RS04135	COG1737	Transcriptional regulator
GE073_RS04145	COG1233	COG1233 Phytoene dehydrogenase and related
GE073_RS04165	COG0395	ABC-type sugar transport system, permease component
GE073_RS04170	COG1175	transmembrane transport
GE073_RS04195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE073_RS04205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE073_RS04210	COG1116	anion transmembrane transporter activity
GE073_RS04220	COG0673	inositol 2-dehydrogenase activity
GE073_RS04235	COG0659	secondary active sulfate transmembrane transporter activity
GE073_RS04265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GE073_RS04285	COG2814	Major facilitator Superfamily
GE073_RS04300	COG2188	Transcriptional regulator
GE073_RS04305	COG1840	ABC-type Fe3 transport system, periplasmic component
GE073_RS04315	COG3842	ATPase activity
GE073_RS04325	COG0483	inositol monophosphate 1-phosphatase activity
GE073_RS04330	COG1227	inorganic diphosphatase activity
GE073_RS04345	COG1609	Transcriptional regulator
GE073_RS04355	COG4209	transmembrane transport
GE073_RS04360	COG0395	ABC-type sugar transport system, permease component
GE073_RS04380	COG1309	transcriptional regulator
GE073_RS04395	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GE073_RS04400	COG1233	COG1233 Phytoene dehydrogenase and related
GE073_RS04405	COG5002	protein histidine kinase activity
GE073_RS04450	COG2318	DinB family
GE073_RS04455	COG1609	Transcriptional regulator
GE073_RS04470	COG0673	inositol 2-dehydrogenase activity
GE073_RS04485	COG1116	anion transmembrane transporter activity
GE073_RS04490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE073_RS04495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE073_RS04500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE073_RS04505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE073_RS04515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE073_RS04525	COG1175	transmembrane transport
GE073_RS04530	COG0395	ABC-type sugar transport system, permease component
GE073_RS04540	COG1063	alcohol dehydrogenase
GE073_RS04550	COG1609	Transcriptional regulator
GE073_RS04560	COG4209	transmembrane transport
GE073_RS04565	COG0395	ABC-type sugar transport system, permease component
GE073_RS04585	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS04600	COG1215	transferase activity, transferring glycosyl groups
GE073_RS04620	COG1216	Glycosyl transferase, family 2
GE073_RS04620	COG0438	transferase activity, transferring glycosyl groups
GE073_RS04640	COG1122	ATPase activity
GE073_RS04645	COG0463	Glycosyl transferase, family 2
GE073_RS04655	COG2508	Transcriptional regulator
GE073_RS04660	COG0686	Belongs to the AlaDH PNT family
GE073_RS04680	COG1027	Aspartate ammonia-lyase
GE073_RS04695	COG0475	glutathione-regulated potassium exporter activity
GE073_RS04700	COG0490	domain, Protein
GE073_RS04715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GE073_RS04720	COG1309	transcriptional regulator
GE073_RS04725	COG2814	Major facilitator Superfamily
GE073_RS04735	COG0667	Aldo Keto reductase
GE073_RS04745	COG3960	tartronate-semialdehyde synthase activity
GE073_RS04755	COG3842	ATPase activity
GE073_RS04765	COG1177	transmembrane transport
GE073_RS04770	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GE073_RS04780	COG1510	regulation of RNA biosynthetic process
GE073_RS04785	COG0517	IMP dehydrogenase activity
GE073_RS04785	COG4175	Glycine betaine
GE073_RS04790	COG4176	ABC-type proline glycine betaine transport system permease component
GE073_RS04795	COG2113	Glycine betaine
GE073_RS04835	COG1487	ribonuclease activity
GE073_RS04840	COG2814	Major facilitator Superfamily
GE073_RS04845	COG2814	Major facilitator Superfamily
GE073_RS04860	COG0824	Thioesterase
GE073_RS04865	COG0561	phosphatase activity
GE073_RS04875	COG1649	PFAM Uncharacterised BCR, COG1649
GE073_RS04880	COG0640	Transcriptional regulator
GE073_RS04960	COG0681	Belongs to the peptidase S26 family
GE073_RS04975	COG0492	ferredoxin-NADP+ reductase activity
GE073_RS04985	COG0322	excinuclease ABC activity
GE073_RS04995	COG2267	carboxylic ester hydrolase activity
GE073_RS05015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE073_RS05020	COG0765	amino acid transport
GE073_RS05025	COG0765	amino acid transport
GE073_RS05040	COG0791	NLP P60 protein
GE073_RS05045	COG1361	Conserved repeat domain
GE073_RS05050	COG4555	ABC transporter
GE073_RS05065	COG2323	membrane
GE073_RS05075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GE073_RS05075	COG2010	Cytochrome c
GE073_RS05090	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GE073_RS05095	COG3336	cytochrome c oxidase
GE073_RS05105	COG1609	Transcriptional regulator
GE073_RS05110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GE073_RS05115	COG0840	transmembrane signaling receptor activity
GE073_RS05125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE073_RS05130	COG1131	(ABC) transporter
GE073_RS05135	COG4152	abc transporter atp-binding protein
GE073_RS05140	COG1668	transmembrane transport
GE073_RS05170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GE073_RS05185	COG1196	nuclear chromosome segregation
GE073_RS05185	COG0739	heme binding
GE073_RS05185	COG0741	lytic transglycosylase activity
GE073_RS05190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GE073_RS05195	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GE073_RS05200	COG2072	flavoprotein involved in K transport
GE073_RS05205	COG2801	Transposase and inactivated derivatives
GE073_RS05220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GE073_RS05230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GE073_RS05245	COG0791	NLP P60 protein
GE073_RS05255	COG0745	RESPONSE REGULATOR receiver
GE073_RS05275	COG0640	Transcriptional regulator
GE073_RS05365	COG2972	Histidine kinase
GE073_RS05370	COG4209	transmembrane transport
GE073_RS05375	COG0395	ABC-type sugar transport system, permease component
GE073_RS05380	COG1653	transport
GE073_RS05395	COG3401	FG-GAP repeat protein
GE073_RS05405	COG0840	transmembrane signaling receptor activity
GE073_RS05415	COG0028	Belongs to the TPP enzyme family
GE073_RS05425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GE073_RS05445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE073_RS05455	COG2197	response regulator
GE073_RS05460	COG4585	Histidine kinase
GE073_RS05475	COG1454	alcohol dehydrogenase
GE073_RS05475	COG1012	belongs to the aldehyde dehydrogenase family
GE073_RS05490	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GE073_RS05495	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GE073_RS05505	COG1177	transmembrane transport
GE073_RS05530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE073_RS05540	COG3458	cephalosporin-C deacetylase activity
GE073_RS05550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GE073_RS05560	COG3347	Dehydrogenase
GE073_RS05560	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS05565	COG4806	L-rhamnose isomerase
GE073_RS05570	COG1070	Carbohydrate kinase
GE073_RS05575	COG1349	DNA-binding transcription factor activity
GE073_RS05590	COG1653	transport
GE073_RS05595	COG4209	transmembrane transport
GE073_RS05600	COG0395	ABC-type sugar transport system, permease component
GE073_RS05615	COG1312	Catalyzes the dehydration of D-mannonate
GE073_RS05650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE073_RS05655	COG0601	transmembrane transport
GE073_RS05660	COG0747	negative chemotaxis
GE073_RS05665	COG4608	Belongs to the ABC transporter superfamily
GE073_RS05670	COG0444	Belongs to the ABC transporter superfamily
GE073_RS05680	COG1846	Transcriptional regulator
GE073_RS05690	COG0247	lactate metabolic process
GE073_RS05695	COG1139	Iron-sulfur cluster binding protein
GE073_RS05700	COG1556	Lactate utilization protein
GE073_RS05705	COG2186	Transcriptional regulator
GE073_RS05720	COG3227	Zinc metalloprotease (Elastase)
GE073_RS05725	COG0500	methyltransferase
GE073_RS05730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GE073_RS05735	COG0628	permease
GE073_RS05745	COG0784	Response regulator, receiver
GE073_RS05745	COG2205	protein histidine kinase activity
GE073_RS05745	COG5002	protein histidine kinase activity
GE073_RS05755	COG0673	inositol 2-dehydrogenase activity
GE073_RS05760	COG2207	Transcriptional regulator
GE073_RS05775	COG2706	6-phosphogluconolactonase activity
GE073_RS05780	COG2223	nitrite transmembrane transporter activity
GE073_RS05785	COG2814	Major facilitator Superfamily
GE073_RS05790	COG1051	belongs to the nudix hydrolase family
GE073_RS05810	COG0753	catalase activity
GE073_RS05815	COG0733	neurotransmitter:sodium symporter activity
GE073_RS05825	COG2115	Belongs to the xylose isomerase family
GE073_RS05830	COG1070	Carbohydrate kinase
GE073_RS05840	COG2081	HI0933 family
GE073_RS05845	COG2267	carboxylic ester hydrolase activity
GE073_RS05850	COG5002	protein histidine kinase activity
GE073_RS05865	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GE073_RS05880	COG0134	indole-3-glycerol-phosphate synthase activity
GE073_RS05885	COG0133	tryptophan synthase activity
GE073_RS05890	COG0159	tryptophan synthase activity
GE073_RS05910	COG1082	Xylose isomerase domain protein TIM barrel
GE073_RS05920	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GE073_RS05945	COG2211	Major facilitator Superfamily
GE073_RS05950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GE073_RS05955	COG0151	Belongs to the GarS family
GE073_RS05960	COG2010	Cytochrome c
GE073_RS05965	COG1917	Cupin 2, conserved barrel domain protein
GE073_RS05965	COG2169	Transcriptional regulator
GE073_RS05975	COG0800	Aldolase
GE073_RS05980	COG2124	cytochrome p450
GE073_RS05985	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GE073_RS05990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GE073_RS05995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GE073_RS06015	COG2972	Histidine kinase
GE073_RS06020	COG4753	response regulator
GE073_RS06020	COG2207	Transcriptional regulator
GE073_RS06030	COG1175	transmembrane transport
GE073_RS06050	COG3328	transposase activity
GE073_RS06095	COG0714	Associated with various cellular activities
GE073_RS06135	COG1413	lyase activity
GE073_RS06140	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GE073_RS06145	COG0673	inositol 2-dehydrogenase activity
GE073_RS06155	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS06165	COG0488	(ABC) transporter
GE073_RS06175	COG2972	Histidine kinase
GE073_RS06180	COG2204	response regulator
GE073_RS06190	COG4209	transmembrane transport
GE073_RS06195	COG0395	ABC-type sugar transport system, permease component
GE073_RS06200	COG1653	transport
GE073_RS06205	COG1874	Beta-galactosidase
GE073_RS06220	COG0697	spore germination
GE073_RS06230	COG1131	(ABC) transporter
GE073_RS06240	COG0747	negative chemotaxis
GE073_RS06255	COG0444	Belongs to the ABC transporter superfamily
GE073_RS06270	COG0534	Mate efflux family protein
GE073_RS06275	COG1609	Transcriptional regulator
GE073_RS06290	COG0446	pyridine nucleotide-disulphide oxidoreductase
GE073_RS06295	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GE073_RS06315	COG0697	spore germination
GE073_RS06340	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GE073_RS06345	COG2207	Transcriptional regulator
GE073_RS06345	COG4753	response regulator
GE073_RS06370	COG0395	ABC-type sugar transport system, permease component
GE073_RS06390	COG1175	transmembrane transport
GE073_RS06395	COG3833	ABC-type maltose transport systems, permease component
GE073_RS06400	COG4124	Belongs to the glycosyl hydrolase 26 family
GE073_RS06415	COG2972	Histidine kinase
GE073_RS06425	COG4209	transmembrane transport
GE073_RS06430	COG0395	ABC-type sugar transport system, permease component
GE073_RS06435	COG2197	response regulator
GE073_RS06440	COG4585	Histidine kinase
GE073_RS06445	COG3239	Fatty acid desaturase
GE073_RS06455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GE073_RS06480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GE073_RS06495	COG0070	glutamate synthase
GE073_RS06495	COG0069	glutamate synthase activity
GE073_RS06495	COG0067	glutamate synthase
GE073_RS06515	COG1396	sequence-specific DNA binding
GE073_RS06525	COG3944	biosynthesis protein
GE073_RS06530	COG0489	protein tyrosine kinase activity
GE073_RS06535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GE073_RS06540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GE073_RS06565	COG0728	peptidoglycan biosynthetic process
GE073_RS06570	COG0438	transferase activity, transferring glycosyl groups
GE073_RS06575	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GE073_RS06590	COG1091	dTDP-4-dehydrorhamnose reductase activity
GE073_RS06595	COG0662	Cupin 2, conserved barrel domain protein
GE073_RS06595	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GE073_RS06600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GE073_RS06610	COG1316	TRANSCRIPTIONal
GE073_RS06655	COG1132	(ABC) transporter
GE073_RS06675	COG1131	(ABC) transporter
GE073_RS06680	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GE073_RS06685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE073_RS06700	COG1793	dna ligase
GE073_RS06700	COG3285	dna ligase
GE073_RS06705	COG1793	dna ligase
GE073_RS06710	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GE073_RS06730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE073_RS06740	COG1214	PFAM Peptidase M22, glycoprotease
GE073_RS06745	COG0456	acetyltransferase
GE073_RS06765	COG0488	(ABC) transporter
GE073_RS06770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GE073_RS06775	COG0315	cyclic pyranopterin monophosphate synthase activity
GE073_RS06780	COG0521	Mo-molybdopterin cofactor biosynthetic process
GE073_RS06785	COG1058	Belongs to the CinA family
GE073_RS06785	COG1546	Belongs to the CinA family
GE073_RS06790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GE073_RS06795	COG0805	protein transport
GE073_RS06805	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GE073_RS06810	COG0459	protein refolding
GE073_RS06815	COG3401	FG-GAP repeat protein
GE073_RS06820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE073_RS06825	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GE073_RS06835	COG0523	cobalamin synthesis protein
GE073_RS06845	COG2205	protein histidine kinase activity
GE073_RS06845	COG3437	response regulator, receiver
GE073_RS06845	COG3850	Histidine kinase
GE073_RS06845	COG4999	Histidine kinase
GE073_RS06850	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GE073_RS06855	COG4999	Histidine kinase
GE073_RS06855	COG3850	Histidine kinase
GE073_RS06855	COG3437	response regulator, receiver
GE073_RS06855	COG2205	protein histidine kinase activity
GE073_RS06860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GE073_RS06865	COG0598	Magnesium transport protein CorA
GE073_RS06890	COG0395	ABC-type sugar transport system, permease component
GE073_RS06895	COG1175	transmembrane transport
GE073_RS06910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GE073_RS06915	COG0864	Transcriptional regulator
GE073_RS06920	COG2337	Toxic component of a toxin-antitoxin (TA) module
GE073_RS06935	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GE073_RS06970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GE073_RS06975	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GE073_RS06985	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GE073_RS06990	COG1285	pathogenesis
GE073_RS07000	COG0735	belongs to the Fur family
GE073_RS07130	COG1842	Phage shock protein A
GE073_RS07140	COG1842	Phage shock protein A
GE073_RS07145	COG4585	Histidine kinase
GE073_RS07150	COG2197	response regulator
GE073_RS07170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GE073_RS07175	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GE073_RS07180	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GE073_RS07185	COG1609	Transcriptional regulator
GE073_RS07190	COG0673	inositol 2-dehydrogenase activity
GE073_RS07205	COG2508	Transcriptional regulator
GE073_RS07210	COG0402	S-adenosylhomocysteine deaminase activity
GE073_RS07215	COG4603	Belongs to the binding-protein-dependent transport system permease family
GE073_RS07220	COG1079	Belongs to the binding-protein-dependent transport system permease family
GE073_RS07225	COG3845	ABC transporter
GE073_RS07230	COG1744	ABC transporter substrate-binding protein PnrA-like
GE073_RS07245	COG0569	domain protein
GE073_RS07250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GE073_RS07255	COG0366	Alpha amylase catalytic
GE073_RS07265	COG0747	negative chemotaxis
GE073_RS07270	COG0601	transmembrane transport
GE073_RS07280	COG0444	Belongs to the ABC transporter superfamily
GE073_RS07285	COG4608	Belongs to the ABC transporter superfamily
GE073_RS07310	COG0300	oxidoreductase activity
GE073_RS07315	COG0739	heme binding
GE073_RS07320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GE073_RS07335	COG3314	Sporulation integral membrane protein YlbJ
GE073_RS07340	COG2346	COG2346, Truncated hemoglobins
GE073_RS07365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GE073_RS07420	COG1090	epimerase
GE073_RS07435	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GE073_RS07440	COG0788	formyltetrahydrofolate deformylase activity
GE073_RS07465	COG0166	Belongs to the GPI family
GE073_RS07470	COG1739	Uncharacterized protein family UPF0029
GE073_RS07480	COG4208	sulfate ABC transporter
GE073_RS07485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GE073_RS07490	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GE073_RS07495	COG0561	phosphatase activity
GE073_RS07500	COG0793	Belongs to the peptidase S41A family
GE073_RS07500	COG3409	Peptidoglycan-binding domain 1 protein
GE073_RS07505	COG0024	Methionine aminopeptidase
GE073_RS07515	COG0006	proline dipeptidase activity
GE073_RS07525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE073_RS07535	COG1482	cell wall glycoprotein biosynthetic process
GE073_RS07540	COG0346	lactoylglutathione lyase activity
GE073_RS07545	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GE073_RS07550	COG1242	4 iron, 4 sulfur cluster binding
GE073_RS07560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GE073_RS07565	COG0671	phosphoesterase, PA-phosphatase related
GE073_RS07570	COG1215	transferase activity, transferring glycosyl groups
GE073_RS07580	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GE073_RS07585	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GE073_RS07600	COG0028	Belongs to the TPP enzyme family
GE073_RS07605	COG0440	acetolactate synthase activity
GE073_RS07610	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GE073_RS07615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GE073_RS07620	COG0473	3-isopropylmalate dehydrogenase activity
GE073_RS07625	COG0450	alkyl hydroperoxide reductase
GE073_RS07640	COG1191	sigma factor activity
GE073_RS07650	COG2172	sigma factor antagonist activity
GE073_RS07655	COG4191	Histidine kinase
GE073_RS07660	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GE073_RS07665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GE073_RS07670	COG4753	response regulator
GE073_RS07670	COG2207	Transcriptional regulator
GE073_RS07675	COG2972	Histidine kinase
GE073_RS07680	COG1879	ABC-type sugar transport system periplasmic component
GE073_RS07685	COG1879	ABC-type sugar transport system periplasmic component
GE073_RS07695	COG4211	Belongs to the binding-protein-dependent transport system permease family
GE073_RS07730	COG2972	Histidine kinase
GE073_RS07730	COG0745	RESPONSE REGULATOR receiver
GE073_RS07735	COG3279	Response regulator of the LytR AlgR family
GE073_RS07755	COG1595	DNA-templated transcription, initiation
GE073_RS07765	COG1131	(ABC) transporter
GE073_RS07770	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GE073_RS07780	COG2911	Protein conserved in bacteria
GE073_RS07780	COG1361	Conserved repeat domain
GE073_RS07780	COG3266	domain, Protein
GE073_RS07785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GE073_RS07805	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GE073_RS07825	COG3850	Histidine kinase
GE073_RS07830	COG2197	response regulator
GE073_RS07840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GE073_RS07845	COG0072	phenylalanine-tRNA ligase activity
GE073_RS07850	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GE073_RS07855	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GE073_RS07900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GE073_RS07920	COG1193	negative regulation of DNA recombination
GE073_RS07925	COG3766	membrane
GE073_RS07935	COG0477	Major facilitator Superfamily
GE073_RS07960	COG1522	sequence-specific DNA binding
GE073_RS07965	COG0436	Aminotransferase
GE073_RS07975	COG2096	Adenosyltransferase
GE073_RS07980	COG0564	pseudouridine synthase activity
GE073_RS07985	COG1393	Belongs to the ArsC family
GE073_RS07990	COG0436	Aminotransferase
GE073_RS07995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE073_RS08005	COG0456	acetyltransferase
GE073_RS08010	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GE073_RS08020	COG2733	membrane
GE073_RS08040	COG1406	Chemotaxis phosphatase CheX
GE073_RS08045	COG0300	oxidoreductase activity
GE073_RS08055	COG1131	(ABC) transporter
GE073_RS08065	COG0436	Aminotransferase
GE073_RS08075	COG3459	Glycosyltransferase 36 associated
GE073_RS08080	COG0737	Belongs to the 5'-nucleotidase family
GE073_RS08095	COG0688	phosphatidylethanolamine metabolic process
GE073_RS08105	COG0438	transferase activity, transferring glycosyl groups
GE073_RS08130	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GE073_RS08140	COG0352	thiamine-phosphate diphosphorylase activity
GE073_RS08150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE073_RS08150	COG2022	thiamine diphosphate biosynthetic process
GE073_RS08155	COG0351	phosphomethylpyrimidine kinase
GE073_RS08180	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GE073_RS08185	COG0463	Glycosyl transferase, family 2
GE073_RS08205	COG0438	transferase activity, transferring glycosyl groups
GE073_RS08215	COG1086	Polysaccharide biosynthesis protein
GE073_RS08240	COG1653	transport
GE073_RS08245	COG4209	transmembrane transport
GE073_RS08250	COG0395	ABC-type sugar transport system, permease component
GE073_RS08265	COG1653	transport
GE073_RS08270	COG0861	Integral membrane protein TerC family
GE073_RS08275	COG2972	Histidine kinase
GE073_RS08280	COG4753	response regulator
GE073_RS08280	COG2207	Transcriptional regulator
GE073_RS08290	COG0628	permease
GE073_RS08305	COG0697	spore germination
GE073_RS08310	COG2207	Transcriptional regulator
GE073_RS08310	COG3708	Transcriptional regulator
GE073_RS08320	COG0384	phenazine biosynthesis protein PhzF
GE073_RS08325	COG4196	transglutaminase domain protein
GE073_RS08335	COG0463	Glycosyl transferase, family 2
GE073_RS08335	COG1216	Glycosyl transferase, family 2
GE073_RS08350	COG2207	Transcriptional regulator
GE073_RS08350	COG4753	response regulator
GE073_RS08355	COG2972	Histidine kinase
GE073_RS08375	COG3250	beta-galactosidase activity
GE073_RS08385	COG2207	Transcriptional regulator
GE073_RS08390	COG2972	Histidine kinase
GE073_RS08410	COG1175	transmembrane transport
GE073_RS08415	COG0395	ABC-type sugar transport system, permease component
GE073_RS08430	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GE073_RS08435	COG2197	response regulator
GE073_RS08450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE073_RS08465	COG2972	Histidine kinase
GE073_RS08470	COG2204	response regulator
GE073_RS08475	COG1472	Belongs to the glycosyl hydrolase 3 family
GE073_RS08480	COG5002	protein histidine kinase activity
GE073_RS08485	COG0745	RESPONSE REGULATOR receiver
GE073_RS08495	COG0673	inositol 2-dehydrogenase activity
GE073_RS08510	COG3711	transcriptional antiterminator
GE073_RS08515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE073_RS08520	COG0246	Mannitol dehydrogenase
GE073_RS08550	COG0778	Nitroreductase
GE073_RS08560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GE073_RS08565	COG0573	inorganic phosphate transmembrane transporter activity
GE073_RS08570	COG0581	inorganic phosphate transmembrane transporter activity
GE073_RS08575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GE073_RS08580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GE073_RS08585	COG0704	Plays a role in the regulation of phosphate uptake
GE073_RS08590	COG0584	glycerophosphoryl diester phosphodiesterase
GE073_RS08605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS08610	COG1120	ATPase activity
GE073_RS08630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GE073_RS08635	COG1971	Probably functions as a manganese efflux pump
GE073_RS08640	COG0237	dephospho-CoA kinase activity
GE073_RS08655	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GE073_RS08665	COG1846	Transcriptional regulator
GE073_RS08705	COG0210	DNA helicase
GE073_RS08715	COG0398	Pfam SNARE associated Golgi protein
GE073_RS08730	COG3345	alpha-galactosidase
GE073_RS08735	COG0277	FAD linked oxidase domain protein
GE073_RS08740	COG2814	Major facilitator Superfamily
GE073_RS08755	COG0492	ferredoxin-NADP+ reductase activity
GE073_RS08775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GE073_RS08785	COG3119	arylsulfatase activity
GE073_RS08795	COG3507	Belongs to the glycosyl hydrolase 43 family
GE073_RS08800	COG1653	transport
GE073_RS08805	COG1175	transmembrane transport
GE073_RS08810	COG0395	ABC-type sugar transport system, permease component
GE073_RS08815	COG4948	Mandelate Racemase Muconate Lactonizing
GE073_RS08820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE073_RS08830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS08850	COG3842	ATPase activity
GE073_RS08865	COG0395	ABC-type sugar transport system, permease component
GE073_RS08900	COG2207	Transcriptional regulator
GE073_RS08900	COG4753	response regulator
GE073_RS08905	COG2972	Histidine kinase
GE073_RS08920	COG3250	beta-galactosidase activity
GE073_RS08935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE073_RS08940	COG3708	Transcriptional regulator
GE073_RS08940	COG2207	Transcriptional regulator
GE073_RS08945	COG1012	belongs to the aldehyde dehydrogenase family
GE073_RS08955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS08960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS08965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS08970	COG0492	ferredoxin-NADP+ reductase activity
GE073_RS08980	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GE073_RS08985	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS09005	COG4824	toxin secretion phage lysis holin
GE073_RS09015	COG0577	efflux transmembrane transporter activity
GE073_RS09020	COG1136	(ABC) transporter
GE073_RS09045	COG4980	gas vesicle protein
GE073_RS09055	COG0469	pyruvate kinase activity
GE073_RS09065	COG1486	melibiose metabolic process
GE073_RS09070	COG0745	RESPONSE REGULATOR receiver
GE073_RS09075	COG5002	protein histidine kinase activity
GE073_RS09080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GE073_RS09105	COG0116	Belongs to the methyltransferase superfamily
GE073_RS09110	COG4122	O-methyltransferase activity
GE073_RS09115	COG1609	Transcriptional regulator
GE073_RS09125	COG1396	sequence-specific DNA binding
GE073_RS09125	COG3800	Transcriptional regulator
GE073_RS09135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GE073_RS09140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GE073_RS09145	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GE073_RS09150	COG2843	Capsule synthesis protein
GE073_RS09155	COG0584	glycerophosphoryl diester phosphodiesterase
GE073_RS09165	COG1164	Oligoendopeptidase f
GE073_RS09220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE073_RS09225	COG0513	Belongs to the DEAD box helicase family
GE073_RS09250	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GE073_RS09255	COG0705	Rhomboid family
GE073_RS09260	COG2738	Putative neutral zinc metallopeptidase
GE073_RS09265	COG0789	Transcriptional regulator
GE073_RS09270	COG0004	ammonium transporteR
GE073_RS09280	COG2176	DNA-directed DNA polymerase activity
GE073_RS09285	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
GE073_RS09295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GE073_RS09300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GE073_RS09310	COG1376	ErfK ybiS ycfS ynhG family protein
GE073_RS09320	COG0167	dihydroorotate dehydrogenase activity
GE073_RS09325	COG2357	RelA SpoT domain protein
GE073_RS09330	COG1187	pseudouridine synthase activity
GE073_RS09340	COG5566	PFAM Mor transcription activator
GE073_RS09355	COG4895	conserved protein (DUF2196)
GE073_RS09375	COG4753	response regulator
GE073_RS09375	COG2207	Transcriptional regulator
GE073_RS09380	COG2972	Histidine kinase
GE073_RS09385	COG0395	ABC-type sugar transport system, permease component
GE073_RS09390	COG4209	transmembrane transport
GE073_RS09400	COG1486	melibiose metabolic process
GE073_RS09410	COG1609	Transcriptional regulator
GE073_RS09415	COG2329	Antibiotic biosynthesis monooxygenase
GE073_RS09425	COG0628	permease
GE073_RS09430	COG1842	Phage shock protein A
GE073_RS09455	COG0438	transferase activity, transferring glycosyl groups
GE073_RS09460	COG3949	Membrane
GE073_RS09465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GE073_RS09490	COG3266	domain, Protein
GE073_RS09490	COG2911	Protein conserved in bacteria
GE073_RS09490	COG1361	Conserved repeat domain
GE073_RS09495	COG2207	Transcriptional regulator
GE073_RS09500	COG1653	transport
GE073_RS09510	COG0667	Aldo Keto reductase
GE073_RS09520	COG2972	Histidine kinase
GE073_RS09525	COG4753	response regulator
GE073_RS09525	COG2207	Transcriptional regulator
GE073_RS09535	COG1175	transmembrane transport
GE073_RS09540	COG0395	ABC-type sugar transport system, permease component
GE073_RS09545	COG1653	transport
GE073_RS09560	COG2972	Histidine kinase
GE073_RS09570	COG1129	ABC transporter
GE073_RS09575	COG1172	Belongs to the binding-protein-dependent transport system permease family
GE073_RS09580	COG1879	ABC-type sugar transport system periplasmic component
GE073_RS09585	COG4753	response regulator
GE073_RS09585	COG2207	Transcriptional regulator
GE073_RS09595	COG0246	Mannitol dehydrogenase
GE073_RS09600	COG2721	sulfolactate sulfo-lyase activity
GE073_RS09605	COG0667	Aldo Keto reductase
GE073_RS09610	COG1063	alcohol dehydrogenase
GE073_RS09620	COG4974	Belongs to the 'phage' integrase family
GE073_RS09640	COG1192	Involved in chromosome partitioning
GE073_RS09645	COG1475	DNA binding
GE073_RS09765	COG1475	DNA binding
GE073_RS09800	COG1475	DNA binding
GE073_RS09855	COG4191	Histidine kinase
GE073_RS09860	COG4191	Histidine kinase
GE073_RS09965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GE073_RS09970	COG2132	Multicopper oxidase
GE073_RS09990	COG1937	Protein conserved in bacteria
GE073_RS10000	COG2217	Heavy metal translocating P-type atpase
GE073_RS10020	COG2226	methyltransferase
GE073_RS10025	COG0398	Pfam SNARE associated Golgi protein
GE073_RS10030	COG0745	RESPONSE REGULATOR receiver
GE073_RS10035	COG2205	protein histidine kinase activity
GE073_RS10075	COG2226	methyltransferase
GE073_RS10090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GE073_RS10100	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GE073_RS10105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GE073_RS10110	COG0346	lactoylglutathione lyase activity
GE073_RS10125	COG2072	flavoprotein involved in K transport
GE073_RS10130	COG2226	methyltransferase
GE073_RS10135	COG2201	protein-glutamate methylesterase activity
GE073_RS10200	COG1082	Xylose isomerase domain protein TIM barrel
GE073_RS10205	COG0673	inositol 2-dehydrogenase activity
GE073_RS10240	COG0673	inositol 2-dehydrogenase activity
GE073_RS10245	COG1940	carbohydrate kinase activity
GE073_RS10255	COG0673	inositol 2-dehydrogenase activity
GE073_RS10270	COG1175	transmembrane transport
GE073_RS10275	COG0395	ABC-type sugar transport system, permease component
GE073_RS10310	COG0673	inositol 2-dehydrogenase activity
GE073_RS10320	COG0789	Transcriptional regulator
GE073_RS10325	COG0667	Aldo Keto reductase
GE073_RS10330	COG2861	carbohydrate metabolic process
GE073_RS10355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE073_RS10365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GE073_RS10375	COG2072	flavoprotein involved in K transport
GE073_RS10415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE073_RS10425	COG0457	Tetratricopeptide repeat
GE073_RS10425	COG0463	Glycosyl transferase, family 2
GE073_RS10430	COG0791	NLP P60 protein
GE073_RS10440	COG2732	(Barnase) inhibitor
GE073_RS10450	COG2205	protein histidine kinase activity
GE073_RS10455	COG0745	RESPONSE REGULATOR receiver
GE073_RS10465	COG3209	COG3209 Rhs family protein
GE073_RS10470	COG0642	Histidine kinase
GE073_RS10475	COG2197	response regulator
GE073_RS10525	COG3628	GPW Gp25 family protein
GE073_RS10530	COG3299	homolog of phage Mu protein gp47
GE073_RS10560	COG2309	aminopeptidase activity
GE073_RS10575	COG1486	melibiose metabolic process
GE073_RS10585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GE073_RS10590	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GE073_RS10610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GE073_RS10615	COG0297	glycogen (starch) synthase activity
GE073_RS10670	COG0673	inositol 2-dehydrogenase activity
GE073_RS10675	COG2207	Transcriptional regulator
GE073_RS10695	COG0785	Cytochrome C biogenesis protein
GE073_RS10705	COG1321	iron dependent repressor
GE073_RS10715	COG3872	metal-dependent enzyme
GE073_RS10725	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GE073_RS10730	COG0006	proline dipeptidase activity
GE073_RS10735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GE073_RS10790	COG0511	ligase activity, forming carbon-carbon bonds
GE073_RS10795	COG0439	Biotin carboxylase
GE073_RS10800	COG1302	Protein conserved in bacteria
GE073_RS10815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GE073_RS10820	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GE073_RS10825	COG1570	exodeoxyribonuclease VII activity
GE073_RS10840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GE073_RS10845	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GE073_RS10855	COG1438	arginine binding
GE073_RS10860	COG0497	DNA recombination
GE073_RS10865	COG0750	zinc metalloprotease
GE073_RS10870	COG0745	RESPONSE REGULATOR receiver
GE073_RS10885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE073_RS10890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GE073_RS10895	COG0022	dehydrogenase e1 component
GE073_RS10900	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE073_RS10905	COG0321	lipoyl(octanoyl) transferase activity
GE073_RS10910	COG2195	Cleaves the N-terminal amino acid of tripeptides
GE073_RS10925	COG1300	Membrane
GE073_RS10930	COG0735	belongs to the Fur family
GE073_RS10935	COG1404	Belongs to the peptidase S8 family
GE073_RS10945	COG4974	Belongs to the 'phage' integrase family
GE073_RS10960	COG1686	Belongs to the peptidase S11 family
GE073_RS10965	COG1366	Belongs to the anti-sigma-factor antagonist family
GE073_RS10970	COG2172	sigma factor antagonist activity
GE073_RS10990	COG0697	spore germination
GE073_RS10995	COG0019	diaminopimelate decarboxylase activity
GE073_RS11000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GE073_RS11005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GE073_RS11005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GE073_RS11015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GE073_RS11015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GE073_RS11020	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GE073_RS11025	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GE073_RS11030	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GE073_RS11040	COG3874	Sporulation protein YtfJ
GE073_RS11045	COG1686	Belongs to the peptidase S11 family
GE073_RS11050	COG2715	membrane protein required for spore maturation
GE073_RS11055	COG0700	Nucleoside recognition
GE073_RS11060	COG1187	pseudouridine synthase activity
GE073_RS11065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE073_RS11070	COG1333	cytochrome c biogenesis protein
GE073_RS11075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GE073_RS11080	COG0745	RESPONSE REGULATOR receiver
GE073_RS11085	COG5002	protein histidine kinase activity
GE073_RS11090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GE073_RS11100	COG1266	CAAX protease self-immunity
GE073_RS11105	COG1408	metallophosphoesterase
GE073_RS11120	COG4862	establishment of competence for transformation
GE073_RS11125	COG2339	peptidase activity
GE073_RS11130	COG2959	enzyme of heme biosynthesis
GE073_RS11145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GE073_RS11175	COG1160	GTP binding
GE073_RS11180	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GE073_RS11215	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GE073_RS11225	COG1129	ABC transporter
GE073_RS11230	COG1172	Belongs to the binding-protein-dependent transport system permease family
GE073_RS11235	COG0776	regulation of translation
GE073_RS11255	COG0142	geranyltranstransferase activity
GE073_RS11260	COG2226	methyltransferase
GE073_RS11270	COG0163	prenyltransferase activity
GE073_RS11275	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GE073_RS11285	COG0105	UTP biosynthetic process
GE073_RS11290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GE073_RS11295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GE073_RS11300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GE073_RS11305	COG4401	Chorismate mutase type I
GE073_RS11315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GE073_RS11320	COG0134	indole-3-glycerol-phosphate synthase activity
GE073_RS11325	COG0135	phosphoribosylanthranilate isomerase activity
GE073_RS11330	COG0133	tryptophan synthase activity
GE073_RS11335	COG0159	tryptophan synthase activity
GE073_RS11340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GE073_RS11345	COG0287	Prephenate dehydrogenase
GE073_RS11360	COG0406	alpha-ribazole phosphatase activity
GE073_RS11395	COG4347	Protein of unknown function (DUF1405)
GE073_RS11405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE073_RS11410	COG1694	Mazg nucleotide pyrophosphohydrolase
GE073_RS11420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GE073_RS11425	COG1803	Methylglyoxal synthase
GE073_RS11430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GE073_RS11435	COG0438	transferase activity, transferring glycosyl groups
GE073_RS11450	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GE073_RS11455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GE073_RS11460	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GE073_RS11470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GE073_RS11470	COG1199	ATP-dependent helicase activity
GE073_RS11475	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GE073_RS11480	COG0402	S-adenosylhomocysteine deaminase activity
GE073_RS11495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GE073_RS11500	COG1250	3-hydroxyacyl-CoA dehydrogenase
GE073_RS11505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GE073_RS11510	COG0017	Asparaginyl-tRNA synthetase
GE073_RS11515	COG3935	DnaD domain protein
GE073_RS11525	COG1528	Iron-storage protein
GE073_RS11555	COG2207	Transcriptional regulator
GE073_RS11560	COG4209	transmembrane transport
GE073_RS11565	COG0395	ABC-type sugar transport system, permease component
GE073_RS11585	COG0697	spore germination
GE073_RS11590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE073_RS11600	COG4209	transmembrane transport
GE073_RS11605	COG0395	ABC-type sugar transport system, permease component
GE073_RS11610	COG1653	transport
GE073_RS11615	COG2207	Transcriptional regulator
GE073_RS11630	COG0235	Class ii aldolase
GE073_RS11635	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GE073_RS11640	COG1850	ribulose-bisphosphate carboxylase activity
GE073_RS11650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GE073_RS11655	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GE073_RS11660	COG0436	Aminotransferase
GE073_RS11670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GE073_RS11675	COG0583	DNA-binding transcription factor activity
GE073_RS11680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GE073_RS11685	COG0066	3-isopropylmalate dehydratase activity
GE073_RS11690	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE073_RS11705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GE073_RS11715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GE073_RS11720	COG1132	(ABC) transporter
GE073_RS11725	COG1132	(ABC) transporter
GE073_RS11730	COG0640	Transcriptional regulator
GE073_RS11740	COG2755	lipolytic protein G-D-S-L family
GE073_RS11745	COG1131	(ABC) transporter
GE073_RS11750	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GE073_RS11760	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GE073_RS11780	COG0564	pseudouridine synthase activity
GE073_RS11785	COG0116	Belongs to the methyltransferase superfamily
GE073_RS11785	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GE073_RS11790	COG1396	sequence-specific DNA binding
GE073_RS11795	COG1012	belongs to the aldehyde dehydrogenase family
GE073_RS11805	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE073_RS11815	COG0735	belongs to the Fur family
GE073_RS11820	COG1121	(ABC) transporter
GE073_RS11825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GE073_RS11830	COG0803	Belongs to the bacterial solute-binding protein 9 family
GE073_RS11835	COG0523	cobalamin synthesis protein
GE073_RS11840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GE073_RS11865	COG1215	transferase activity, transferring glycosyl groups
GE073_RS11885	COG1307	EDD domain protein, DegV family
GE073_RS11890	COG2329	Antibiotic biosynthesis monooxygenase
GE073_RS11895	COG5386	Cell surface protein
GE073_RS11900	COG1361	Conserved repeat domain
GE073_RS11915	COG1120	ATPase activity
GE073_RS11925	COG1361	Conserved repeat domain
GE073_RS11925	COG2911	Protein conserved in bacteria
GE073_RS11925	COG3266	domain, Protein
GE073_RS11950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GE073_RS11965	COG1547	Domain of unknown function (DUF309)
GE073_RS11970	COG0288	reversible hydration of carbon dioxide
GE073_RS11980	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GE073_RS11990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE073_RS11995	COG1116	anion transmembrane transporter activity
GE073_RS12000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE073_RS12025	COG1279	arginine transmembrane transporter activity
GE073_RS12030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE073_RS12035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GE073_RS12040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GE073_RS12045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GE073_RS12050	COG2136	Putative SAM-dependent methyltransferase
GE073_RS12050	COG2521	methyltransferase
GE073_RS12055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GE073_RS12060	COG1923	regulation of RNA biosynthetic process
GE073_RS12065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE073_RS12080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GE073_RS12085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GE073_RS12110	COG0464	growth
GE073_RS12115	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GE073_RS12120	COG0789	Transcriptional regulator
GE073_RS12125	COG0174	glutamine synthetase
GE073_RS12130	COG0454	-acetyltransferase
GE073_RS12140	COG3534	alpha-L-arabinofuranosidase
GE073_RS12155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GE073_RS12160	COG1388	LysM domain
GE073_RS12170	COG0667	Aldo Keto reductase
GE073_RS12180	COG1011	Hydrolase
GE073_RS12185	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GE073_RS12190	COG0646	methionine synthase
GE073_RS12190	COG1410	methionine synthase
GE073_RS12195	COG1234	tRNA 3'-trailer cleavage
GE073_RS12200	COG1205	dead DEAH box helicase
GE073_RS12200	COG1111	helicase
GE073_RS12210	COG0647	UMP catabolic process
GE073_RS12215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GE073_RS12220	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GE073_RS12225	COG1119	ATPase activity
GE073_RS12230	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GE073_RS12235	COG0515	serine threonine protein kinase
GE073_RS12240	COG0488	(ABC) transporter
GE073_RS12245	COG0745	RESPONSE REGULATOR receiver
GE073_RS12250	COG3850	Histidine kinase
GE073_RS12250	COG5002	protein histidine kinase activity
GE073_RS12260	COG3153	acetyltransferase
GE073_RS12260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GE073_RS12265	COG0456	acetyltransferase
GE073_RS12275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GE073_RS12275	COG0321	lipoyl(octanoyl) transferase activity
GE073_RS12280	COG1132	(ABC) transporter
GE073_RS12285	COG1132	(ABC) transporter
GE073_RS12290	COG1193	negative regulation of DNA recombination
GE073_RS12300	COG2860	membrane
GE073_RS12305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GE073_RS12320	COG0022	dehydrogenase e1 component
GE073_RS12340	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GE073_RS12350	COG0493	'glutamate synthase
GE073_RS12355	COG1653	transport
GE073_RS12360	COG2972	Histidine kinase
GE073_RS12365	COG2197	response regulator
GE073_RS12370	COG3507	Belongs to the glycosyl hydrolase 43 family
GE073_RS12375	COG1136	(ABC) transporter
GE073_RS12380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GE073_RS12390	COG1136	(ABC) transporter
GE073_RS12390	COG0577	efflux transmembrane transporter activity
GE073_RS12400	COG2207	Transcriptional regulator
GE073_RS12400	COG1609	Transcriptional regulator
GE073_RS12415	COG1175	transmembrane transport
GE073_RS12440	COG1175	transmembrane transport
GE073_RS12445	COG0395	ABC-type sugar transport system, permease component
GE073_RS12450	COG3507	Belongs to the glycosyl hydrolase 43 family
GE073_RS12475	COG0551	DNA topoisomerase type I activity
GE073_RS12475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GE073_RS12480	COG4533	DNA binding
GE073_RS12515	COG2258	MOSC domain
GE073_RS12520	COG0492	ferredoxin-NADP+ reductase activity
GE073_RS12530	COG4974	Belongs to the 'phage' integrase family
GE073_RS12535	COG1408	metallophosphoesterase
GE073_RS12550	COG0640	Transcriptional regulator
GE073_RS12555	COG4974	Belongs to the 'phage' integrase family
GE073_RS12560	COG0673	inositol 2-dehydrogenase activity
GE073_RS12565	COG2207	Transcriptional regulator
GE073_RS12565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS12570	COG4109	DRTGG domain
GE073_RS12580	COG2224	Isocitrate lyase
GE073_RS12585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GE073_RS12660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GE073_RS12665	COG2267	carboxylic ester hydrolase activity
GE073_RS12670	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS12735	COG5646	InterPro IPR014922
GE073_RS12755	COG2837	iron assimilation
GE073_RS12760	COG2822	iron ion transport
GE073_RS12765	COG0672	)-iron permease
GE073_RS12775	COG1253	flavin adenine dinucleotide binding
GE073_RS12780	COG1253	flavin adenine dinucleotide binding
GE073_RS12785	COG0105	UTP biosynthetic process
GE073_RS12825	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GE073_RS12830	COG1132	(ABC) transporter
GE073_RS12835	COG1132	(ABC) transporter
GE073_RS12855	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GE073_RS12900	COG3119	arylsulfatase activity
GE073_RS12905	COG3250	beta-galactosidase activity
GE073_RS12910	COG4977	sequence-specific DNA binding
GE073_RS12930	COG0395	ABC-type sugar transport system, permease component
GE073_RS12935	COG4209	transmembrane transport
GE073_RS12950	COG3119	arylsulfatase activity
GE073_RS12960	COG3119	arylsulfatase activity
GE073_RS12965	COG4154	Belongs to the RbsD FucU family
GE073_RS12980	COG0823	Involved in the tonB-independent uptake of proteins
GE073_RS12990	COG0395	ABC-type sugar transport system, permease component
GE073_RS12995	COG1175	transmembrane transport
GE073_RS13020	COG2017	converts alpha-aldose to the beta-anomer
GE073_RS13035	COG0395	ABC-type sugar transport system, permease component
GE073_RS13040	COG4209	transmembrane transport
GE073_RS13060	COG0148	phosphopyruvate hydratase activity
GE073_RS13080	COG3250	beta-galactosidase activity
GE073_RS13085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GE073_RS13090	COG1012	belongs to the aldehyde dehydrogenase family
GE073_RS13095	COG1024	Enoyl-CoA hydratase
GE073_RS13100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GE073_RS13115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GE073_RS13135	COG4221	oxidoreductase activity
GE073_RS13140	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS13145	COG1063	alcohol dehydrogenase
GE073_RS13150	COG4948	Mandelate Racemase Muconate Lactonizing
GE073_RS13155	COG1414	Transcriptional regulator
GE073_RS13175	COG4753	response regulator
GE073_RS13175	COG2207	Transcriptional regulator
GE073_RS13190	COG2207	Transcriptional regulator
GE073_RS13190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS13200	COG3693	PFAM glycoside hydrolase, family 10
GE073_RS13220	COG0395	ABC-type sugar transport system, permease component
GE073_RS13225	COG4209	transmembrane transport
GE073_RS13230	COG2207	Transcriptional regulator
GE073_RS13230	COG0662	Cupin 2, conserved barrel domain protein
GE073_RS13235	COG3119	arylsulfatase activity
GE073_RS13245	COG3119	arylsulfatase activity
GE073_RS13255	COG2207	Transcriptional regulator
GE073_RS13255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS13260	COG0800	Aldolase
GE073_RS13270	COG4948	Mandelate Racemase Muconate Lactonizing
GE073_RS13280	COG0395	ABC-type sugar transport system, permease component
GE073_RS13285	COG1175	transmembrane transport
GE073_RS13300	COG4753	response regulator
GE073_RS13300	COG2207	Transcriptional regulator
GE073_RS13305	COG2972	Histidine kinase
GE073_RS13315	COG1012	belongs to the aldehyde dehydrogenase family
GE073_RS13320	COG1388	LysM domain
GE073_RS13320	COG0791	NLP P60 protein
GE073_RS13320	COG3103	Sh3 type 3 domain protein
GE073_RS13325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GE073_RS13350	COG1335	isochorismatase
GE073_RS13355	COG2363	Small membrane protein
GE073_RS13380	COG0583	DNA-binding transcription factor activity
GE073_RS13400	COG1136	(ABC) transporter
GE073_RS13405	COG2205	protein histidine kinase activity
GE073_RS13410	COG0745	RESPONSE REGULATOR receiver
GE073_RS13425	COG3695	enzyme binding
GE073_RS13435	COG1199	ATP-dependent helicase activity
GE073_RS13440	COG0702	epimerase
GE073_RS13450	COG0318	PFAM AMP-dependent synthetase and ligase
GE073_RS13455	COG1960	acyl-CoA dehydrogenase activity
GE073_RS13460	COG0183	Belongs to the thiolase family
GE073_RS13465	COG1024	Enoyl-CoA hydratase
GE073_RS13465	COG1250	3-hydroxyacyl-CoA dehydrogenase
GE073_RS13470	COG0247	lactate metabolic process
GE073_RS13470	COG2181	nitrate reductase activity
GE073_RS13475	COG1309	transcriptional regulator
GE073_RS13480	COG2086	electron transfer activity
GE073_RS13485	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GE073_RS13490	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS13495	COG3480	Lon protease (S16) C-terminal proteolytic domain
GE073_RS13515	COG1011	Hydrolase
GE073_RS13525	COG2329	Antibiotic biosynthesis monooxygenase
GE073_RS13545	COG1435	thymidine kinase activity
GE073_RS13550	COG1363	Peptidase, m42
GE073_RS13555	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GE073_RS13565	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GE073_RS13570	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GE073_RS13600	COG2508	Transcriptional regulator
GE073_RS13610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GE073_RS13615	COG1012	belongs to the aldehyde dehydrogenase family
GE073_RS13625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE073_RS13660	COG0456	acetyltransferase
GE073_RS13660	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GE073_RS13665	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS13670	COG2706	6-phosphogluconolactonase activity
GE073_RS13675	COG1368	sulfuric ester hydrolase activity
GE073_RS13680	COG3766	membrane
GE073_RS13705	COG1403	HNH endonuclease
GE073_RS13715	COG1764	response to oxidative stress
GE073_RS13735	COG1764	response to oxidative stress
GE073_RS13760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GE073_RS13770	COG0456	acetyltransferase
GE073_RS13785	COG3973	AAA domain
GE073_RS13790	COG3069	C4-dicarboxylate transmembrane transporter activity
GE073_RS13805	COG0531	amino acid
GE073_RS13810	COG0697	spore germination
GE073_RS13835	COG1233	COG1233 Phytoene dehydrogenase and related
GE073_RS13845	COG1320	monovalent cation:proton antiporter activity
GE073_RS13850	COG2212	antiporter activity
GE073_RS13855	COG1863	multisubunit Na H antiporter MnhE subunit
GE073_RS13860	COG0651	ATP synthesis coupled electron transport
GE073_RS13865	COG1006	Multisubunit Na H antiporter MnhC subunit
GE073_RS13870	COG2111	Na H antiporter
GE073_RS13870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GE073_RS13875	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GE073_RS13880	COG2217	Heavy metal translocating P-type atpase
GE073_RS13885	COG3973	AAA domain
GE073_RS13890	COG2197	response regulator
GE073_RS13895	COG4585	Histidine kinase
GE073_RS13905	COG3326	Membrane
GE073_RS13910	COG1643	Atp-dependent helicase
GE073_RS13915	COG0598	Magnesium transport protein CorA
GE073_RS13925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GE073_RS13935	COG2217	Heavy metal translocating P-type atpase
GE073_RS13940	COG2203	Gaf domain
GE073_RS13940	COG3706	GGDEF domain
GE073_RS13940	COG5001	Diguanylate cyclase
GE073_RS13940	COG4251	negative regulation of phosphorylation
GE073_RS13945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE073_RS13955	COG0393	Putative heavy-metal-binding
GE073_RS13965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GE073_RS13975	COG5002	protein histidine kinase activity
GE073_RS13995	COG1268	BioY protein
GE073_RS14000	COG1979	alcohol dehydrogenase
GE073_RS14005	COG4550	Control of competence regulator ComK, YlbF/YmcA
GE073_RS14010	COG4869	propanediol catabolic process
GE073_RS14015	COG1013	pyruvate-flavodoxin oxidoreductase activity
GE073_RS14020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GE073_RS14020	COG0674	pyruvate-flavodoxin oxidoreductase activity
GE073_RS14030	COG2359	stage V sporulation protein S
GE073_RS14035	COG1692	metallophosphoesterase
GE073_RS14040	COG1418	mRNA catabolic process
GE073_RS14045	COG2137	regulation of response to DNA damage stimulus
GE073_RS14050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GE073_RS14055	COG1546	Belongs to the CinA family
GE073_RS14055	COG1058	Belongs to the CinA family
GE073_RS14060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GE073_RS14070	COG1426	Protein conserved in bacteria
GE073_RS14085	COG0300	oxidoreductase activity
GE073_RS14090	COG0612	Peptidase, M16
GE073_RS14095	COG0612	Peptidase, M16
GE073_RS14105	COG1674	ftsk spoiiie
GE073_RS14105	COG4980	gas vesicle protein
GE073_RS14115	COG0740	serine-type endopeptidase activity
GE073_RS14120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GE073_RS14125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GE073_RS14130	COG0527	aspartate kinase activity
GE073_RS14135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GE073_RS14140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GE073_RS14145	COG0756	dUTP diphosphatase activity
GE073_RS14150	COG0612	Peptidase, M16
GE073_RS14155	COG0726	polysaccharide deacetylase
GE073_RS14160	COG1185	polyribonucleotide nucleotidyltransferase activity
GE073_RS14165	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GE073_RS14170	COG0196	riboflavin kinase activity
GE073_RS14175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GE073_RS14180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GE073_RS14185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GE073_RS14190	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GE073_RS14195	COG1358	cellular component organization or biogenesis
GE073_RS14200	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GE073_RS14205	COG0195	Participates in both transcription termination and antitermination
GE073_RS14210	COG0779	Required for maturation of 30S ribosomal subunits
GE073_RS14215	COG2176	DNA-directed DNA polymerase activity
GE073_RS14220	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GE073_RS14225	COG0750	zinc metalloprotease
GE073_RS14230	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GE073_RS14235	COG4589	Belongs to the CDS family
GE073_RS14240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GE073_RS14245	COG0233	cytoplasmic translational termination
GE073_RS14250	COG0528	UMP kinase activity
GE073_RS14255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GE073_RS14260	COG0052	Belongs to the universal ribosomal protein uS2 family
GE073_RS14285	COG1191	sigma factor activity
GE073_RS14295	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GE073_RS14300	COG1776	CheC inhibitor of MCP methylation
GE073_RS14305	COG0835	chemotaxis
GE073_RS14310	COG0643	Histidine kinase
GE073_RS14310	COG2198	Histidine kinase
GE073_RS14315	COG2201	protein-glutamate methylesterase activity
GE073_RS14320	COG0455	bacterial-type flagellum organization
GE073_RS14325	COG1419	protein localization to endoplasmic reticulum
GE073_RS14330	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GE073_RS14335	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GE073_RS14340	COG1684	flagellar biosynthetic protein fliR
GE073_RS14345	COG1987	bacterial-type flagellum assembly
GE073_RS14350	COG1338	Plays a role in the flagellum-specific transport system
GE073_RS14360	COG2201	protein-glutamate methylesterase activity
GE073_RS14365	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE073_RS14365	COG1776	CheC inhibitor of MCP methylation
GE073_RS14370	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE073_RS14385	COG4786	Flagellar basal body rod
GE073_RS14390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GE073_RS14410	COG1157	protein secretion by the type III secretion system
GE073_RS14420	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE073_RS14425	COG1766	The M ring may be actively involved in energy transduction
GE073_RS14435	COG1558	bacterial-type flagellum-dependent cell motility
GE073_RS14440	COG1815	bacterial-type flagellum-dependent cell motility
GE073_RS14445	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GE073_RS14450	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GE073_RS14455	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GE073_RS14460	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GE073_RS14465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GE073_RS14470	COG0758	DNA mediated transformation
GE073_RS14470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GE073_RS14475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GE073_RS14480	COG0045	succinate-CoA ligase (ADP-forming) activity
GE073_RS14490	COG0792	nuclease activity
GE073_RS14495	COG2257	FlhB HrpN YscU SpaS Family
GE073_RS14510	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GE073_RS14515	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GE073_RS14525	COG0335	large ribosomal subunit rRNA binding
GE073_RS14530	COG0336	Belongs to the RNA methyltransferase TrmD family
GE073_RS14535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GE073_RS14540	COG0228	four-way junction DNA binding
GE073_RS14545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GE073_RS14550	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GE073_RS14555	COG0552	protein localization to endoplasmic reticulum
GE073_RS14560	COG1196	nuclear chromosome segregation
GE073_RS14565	COG0571	ribonuclease III activity
GE073_RS14570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GE073_RS14575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GE073_RS14580	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS14585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GE073_RS14595	COG0416	fatty acid biosynthetic process
GE073_RS14600	COG1349	DNA-binding transcription factor activity
GE073_RS14605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GE073_RS14615	COG1323	Belongs to the UPF0348 family
GE073_RS14620	COG3480	Lon protease (S16) C-terminal proteolytic domain
GE073_RS14625	COG3314	Sporulation integral membrane protein YlbJ
GE073_RS14630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GE073_RS14635	COG0742	ribosomal rna small subunit methyltransferase
GE073_RS14660	COG0601	transmembrane transport
GE073_RS14670	COG0864	Transcriptional regulator
GE073_RS14675	COG1653	transport
GE073_RS14685	COG2972	Histidine kinase
GE073_RS14690	COG0395	ABC-type sugar transport system, permease component
GE073_RS14695	COG1175	transmembrane transport
GE073_RS14700	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GE073_RS14705	COG0709	Synthesizes selenophosphate from selenide and ATP
GE073_RS14710	COG0701	Predicted permease
GE073_RS14720	COG3209	COG3209 Rhs family protein
GE073_RS14730	COG0765	amino acid transport
GE073_RS14740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GE073_RS14745	COG1408	metallophosphoesterase
GE073_RS14750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE073_RS14765	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GE073_RS14770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE073_RS14780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE073_RS14795	COG0395	ABC-type sugar transport system, permease component
GE073_RS14800	COG4209	transmembrane transport
GE073_RS14820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GE073_RS14830	COG0697	spore germination
GE073_RS14850	COG0395	ABC-type sugar transport system, permease component
GE073_RS14855	COG1175	transmembrane transport
GE073_RS14880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GE073_RS14885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GE073_RS14905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE073_RS14910	COG3833	ABC-type maltose transport systems, permease component
GE073_RS14915	COG1175	transmembrane transport
GE073_RS14920	COG2182	Extracellular solute-binding protein
GE073_RS14930	COG1609	Transcriptional regulator
GE073_RS14950	COG2135	peptidase activity
GE073_RS14975	COG0596	Alpha beta hydrolase
GE073_RS14980	COG1522	sequence-specific DNA binding
GE073_RS14990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GE073_RS14995	COG1307	EDD domain protein, DegV family
GE073_RS15000	COG1461	Dihydroxyacetone kinase
GE073_RS15005	COG1302	Protein conserved in bacteria
GE073_RS15010	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GE073_RS15025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GE073_RS15030	COG1162	GTPase activity
GE073_RS15035	COG0515	serine threonine protein kinase
GE073_RS15035	COG2815	serine threonine protein kinase
GE073_RS15040	COG0631	protein serine/threonine phosphatase activity
GE073_RS15045	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GE073_RS15050	COG1368	sulfuric ester hydrolase activity
GE073_RS15055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GE073_RS15055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GE073_RS15065	COG0242	peptide deformylase activity
GE073_RS15070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GE073_RS15075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GE073_RS15080	COG1758	RNA polymerase activity
GE073_RS15085	COG0194	GDP metabolic process
GE073_RS15090	COG2052	Domain of unknown function (DUF370)
GE073_RS15100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS15105	COG1120	ATPase activity
GE073_RS15110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GE073_RS15115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GE073_RS15125	COG0613	PHP domain protein
GE073_RS15130	COG0583	DNA-binding transcription factor activity
GE073_RS15155	COG1061	Type III restriction enzyme res subunit
GE073_RS15160	COG1473	amidohydrolase
GE073_RS15170	COG0772	Belongs to the SEDS family
GE073_RS15175	COG1302	Protein conserved in bacteria
GE073_RS15180	COG0387	Pfam Sodium calcium exchanger
GE073_RS15185	COG4838	Belongs to the UPF0358 family
GE073_RS15195	COG2309	aminopeptidase activity
GE073_RS15205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GE073_RS15210	COG2268	Band 7 protein
GE073_RS15220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GE073_RS15225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE073_RS15230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GE073_RS15235	COG0454	-acetyltransferase
GE073_RS15240	COG0123	including yeast histone deacetylase and acetoin utilization protein
GE073_RS15245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GE073_RS15250	COG1609	Transcriptional regulator
GE073_RS15265	COG0693	protein deglycase activity
GE073_RS15270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GE073_RS15275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE073_RS15275	COG2190	(PTS) system
GE073_RS15275	COG1263	PTS System
GE073_RS15280	COG1832	CoA-binding protein
GE073_RS15285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GE073_RS15290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GE073_RS15300	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GE073_RS15305	COG1070	Carbohydrate kinase
GE073_RS15315	COG4493	Belongs to the UPF0637 family
GE073_RS15320	COG0477	Major facilitator Superfamily
GE073_RS15325	COG1982	Orn Lys Arg decarboxylase major
GE073_RS15375	COG2814	Major facilitator Superfamily
GE073_RS15380	COG1309	transcriptional regulator
GE073_RS15390	COG0697	spore germination
GE073_RS15425	COG0581	inorganic phosphate transmembrane transporter activity
GE073_RS15430	COG0573	inorganic phosphate transmembrane transporter activity
GE073_RS15445	COG1376	ErfK ybiS ycfS ynhG family protein
GE073_RS15460	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GE073_RS15515	COG1136	(ABC) transporter
GE073_RS15515	COG0577	efflux transmembrane transporter activity
GE073_RS15530	COG0577	efflux transmembrane transporter activity
GE073_RS15530	COG1136	(ABC) transporter
GE073_RS15535	COG0673	inositol 2-dehydrogenase activity
GE073_RS15540	COG0386	Belongs to the glutathione peroxidase family
GE073_RS15580	COG0456	acetyltransferase
GE073_RS15595	COG0579	oxidoreductase
GE073_RS15605	COG0284	orotidine-5'-phosphate decarboxylase activity
GE073_RS15610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GE073_RS15615	COG0505	Belongs to the CarA family
GE073_RS15625	COG0540	Belongs to the ATCase OTCase family
GE073_RS15630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GE073_RS15635	COG0436	Aminotransferase
GE073_RS15640	COG0564	pseudouridine synthase activity
GE073_RS15645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GE073_RS15650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GE073_RS15675	COG3599	regulation of cell shape
GE073_RS15680	COG2302	S4 RNA-binding domain
GE073_RS15685	COG0762	integral membrane protein
GE073_RS15690	COG1799	cell septum assembly
GE073_RS15695	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GE073_RS15705	COG1873	PFAM PRC-barrel domain
GE073_RS15710	COG1191	sigma factor activity
GE073_RS15730	COG1725	Transcriptional regulator
GE073_RS15735	COG1132	(ABC) transporter
GE073_RS15740	COG1191	sigma factor activity
GE073_RS15750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GE073_RS15755	COG0849	cell division
GE073_RS15760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GE073_RS15770	COG0772	Belongs to the SEDS family
GE073_RS15775	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GE073_RS15780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GE073_RS15785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GE073_RS15790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GE073_RS15795	COG0768	penicillin binding
GE073_RS15800	COG0768	penicillin binding
GE073_RS15810	COG0275	rRNA processing
GE073_RS15815	COG2001	Belongs to the MraZ family
GE073_RS15820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GE073_RS15825	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GE073_RS15860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GE073_RS15875	COG1316	TRANSCRIPTIONal
GE073_RS15885	COG1217	gtp-binding protein TYPA
GE073_RS15895	COG0861	Integral membrane protein TerC family
GE073_RS15900	COG0861	Integral membrane protein TerC family
GE073_RS15910	COG0741	lytic transglycosylase activity
GE073_RS15935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GE073_RS15940	COG2384	SAM-dependent methyltransferase
GE073_RS15955	COG0358	DNA primase activity
GE073_RS15960	COG1671	Belongs to the UPF0178 family
GE073_RS15965	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GE073_RS15970	COG0751	glycine-tRNA ligase activity
GE073_RS15975	COG0752	glycyl-tRNA synthetase alpha subunit
GE073_RS15980	COG1381	Involved in DNA repair and RecF pathway recombination
GE073_RS15990	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GE073_RS15995	COG0295	cytidine deaminase activity
GE073_RS16000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GE073_RS16005	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GE073_RS16010	COG1480	7TM receptor with intracellular HD hydrolase
GE073_RS16015	COG1702	phosphate starvation-inducible protein PhoH
GE073_RS16035	COG4864	UPF0365 protein
GE073_RS16040	COG1030	water channel activity
GE073_RS16045	COG1610	YqeY-like protein
GE073_RS16050	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GE073_RS16055	COG0537	adenosine 5'-monophosphoramidase activity
GE073_RS16070	COG1074	ATP-dependent DNA helicase activity
GE073_RS16075	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GE073_RS16080	COG0419	ATPase involved in DNA repair
GE073_RS16085	COG0420	3'-5' exonuclease activity
GE073_RS16095	COG1283	sodium-dependent phosphate transmembrane transporter activity
GE073_RS16105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GE073_RS16110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GE073_RS16120	COG1994	Peptidase M50
GE073_RS16125	COG2264	protein methyltransferase activity
GE073_RS16130	COG4264	IucA IucC family
GE073_RS16135	COG0019	diaminopimelate decarboxylase activity
GE073_RS16145	COG4264	IucA IucC family
GE073_RS16150	COG4264	IucA IucC family
GE073_RS16170	COG1120	ATPase activity
GE073_RS16180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS16185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS16190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS16195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GE073_RS16215	COG0395	ABC-type sugar transport system, permease component
GE073_RS16220	COG4209	transmembrane transport
GE073_RS16235	COG1802	Transcriptional regulator
GE073_RS16240	COG0484	heat shock protein binding
GE073_RS16245	COG0443	Heat shock 70 kDa protein
GE073_RS16255	COG1420	regulation of RNA biosynthetic process
GE073_RS16265	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GE073_RS16265	COG0165	Argininosuccinate lyase
GE073_RS16280	COG1785	Belongs to the alkaline phosphatase family
GE073_RS16290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GE073_RS16295	COG0481	GTPase activity
GE073_RS16320	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GE073_RS16325	COG0268	Binds directly to 16S ribosomal RNA
GE073_RS16330	COG1466	dna polymerase III delta subunit
GE073_RS16340	COG1595	DNA-templated transcription, initiation
GE073_RS16345	COG3279	Response regulator of the LytR AlgR family
GE073_RS16350	COG2972	Histidine kinase
GE073_RS16370	COG0667	Aldo Keto reductase
GE073_RS16395	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS16405	COG3206	protein involved in exopolysaccharide biosynthesis
GE073_RS16415	COG2409	Drug exporters of the RND superfamily
GE073_RS16420	COG3833	ABC-type maltose transport systems, permease component
GE073_RS16425	COG1175	transmembrane transport
GE073_RS16430	COG2182	Extracellular solute-binding protein
GE073_RS16435	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GE073_RS16440	COG1349	DNA-binding transcription factor activity
GE073_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS16450	COG1609	Transcriptional regulator
GE073_RS16455	COG1653	transport
GE073_RS16470	COG1796	DNA polymerase
GE073_RS16470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GE073_RS16500	COG0583	DNA-binding transcription factor activity
GE073_RS16530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GE073_RS16545	COG2333	competence protein COMEC
GE073_RS16545	COG0658	competence protein
GE073_RS16560	COG1555	photosystem II stabilization
GE073_RS16560	COG1596	polysaccharide export
GE073_RS16565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE073_RS16570	COG0495	leucyl-tRNA aminoacylation
GE073_RS16580	COG3459	Glycosyltransferase 36 associated
GE073_RS16600	COG0395	ABC-type sugar transport system, permease component
GE073_RS16605	COG1175	transmembrane transport
GE073_RS16620	COG0395	ABC-type sugar transport system, permease component
GE073_RS16635	COG1653	transport
GE073_RS16640	COG2226	methyltransferase
GE073_RS16645	COG2996	Protein conserved in bacteria
GE073_RS16650	COG0799	negative regulation of ribosome biogenesis
GE073_RS16655	COG1713	HD superfamily hydrolase involved in NAD metabolism
GE073_RS16660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GE073_RS16665	COG1534	Rna-binding protein
GE073_RS16670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GE073_RS16675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GE073_RS16680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GE073_RS16695	COG0714	Associated with various cellular activities
GE073_RS16705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GE073_RS16715	COG2807	transmembrane transport
GE073_RS16725	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GE073_RS16735	COG2011	ABC-type metal ion transport system permease component
GE073_RS16740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GE073_RS16760	COG0789	Transcriptional regulator
GE073_RS16765	COG0667	Aldo Keto reductase
GE073_RS16770	COG0673	inositol 2-dehydrogenase activity
GE073_RS16780	COG5002	protein histidine kinase activity
GE073_RS16785	COG0745	RESPONSE REGULATOR receiver
GE073_RS16795	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GE073_RS16800	COG0402	S-adenosylhomocysteine deaminase activity
GE073_RS16805	COG1695	Transcriptional regulator
GE073_RS16820	COG2972	Histidine kinase
GE073_RS16825	COG1653	transport
GE073_RS16830	COG0395	ABC-type sugar transport system, permease component
GE073_RS16835	COG4209	transmembrane transport
GE073_RS16840	COG2207	Transcriptional regulator
GE073_RS16840	COG4753	response regulator
GE073_RS16845	COG3973	AAA domain
GE073_RS16850	COG1335	isochorismatase
GE073_RS16855	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GE073_RS16860	COG0179	Fumarylacetoacetate (FAA) hydrolase
GE073_RS16865	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS16870	COG4154	Belongs to the RbsD FucU family
GE073_RS16880	COG2721	sulfolactate sulfo-lyase activity
GE073_RS16890	COG1609	Transcriptional regulator
GE073_RS16900	COG0791	NLP P60 protein
GE073_RS16910	COG1917	Cupin 2, conserved barrel domain protein
GE073_RS16910	COG4977	sequence-specific DNA binding
GE073_RS16930	COG1846	Transcriptional regulator
GE073_RS16935	COG2217	Heavy metal translocating P-type atpase
GE073_RS16970	COG2197	response regulator
GE073_RS16975	COG3437	response regulator, receiver
GE073_RS16975	COG0784	Response regulator, receiver
GE073_RS16980	COG4191	Histidine kinase
GE073_RS17000	COG0446	pyridine nucleotide-disulphide oxidoreductase
GE073_RS17005	COG2169	Transcriptional regulator
GE073_RS17010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GE073_RS17035	COG1069	ribulokinase activity
GE073_RS17055	COG1120	ATPase activity
GE073_RS17060	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS17065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS17085	COG1970	mechanosensitive ion channel activity
GE073_RS17095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GE073_RS17100	COG0464	growth
GE073_RS17105	COG1621	beta-fructofuranosidase activity
GE073_RS17130	COG0477	Major facilitator Superfamily
GE073_RS17155	COG2972	Histidine kinase
GE073_RS17165	COG1653	transport
GE073_RS17170	COG0395	ABC-type sugar transport system, permease component
GE073_RS17175	COG1175	transmembrane transport
GE073_RS17195	COG1175	transmembrane transport
GE073_RS17215	COG0395	ABC-type sugar transport system, permease component
GE073_RS17245	COG1609	Transcriptional regulator
GE073_RS17250	COG1917	Cupin 2, conserved barrel domain protein
GE073_RS17250	COG2207	Transcriptional regulator
GE073_RS17255	COG3250	beta-galactosidase activity
GE073_RS17265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE073_RS17275	COG1653	transport
GE073_RS17280	COG0395	ABC-type sugar transport system, permease component
GE073_RS17285	COG4209	transmembrane transport
GE073_RS17290	COG1653	transport
GE073_RS17295	COG2207	Transcriptional regulator
GE073_RS17300	COG0673	inositol 2-dehydrogenase activity
GE073_RS17305	COG1917	Cupin 2, conserved barrel domain protein
GE073_RS17305	COG2207	Transcriptional regulator
GE073_RS17320	COG2084	Dehydrogenase
GE073_RS17325	COG2610	gluconate transmembrane transporter activity
GE073_RS17335	COG1473	amidohydrolase
GE073_RS17340	COG1760	l-serine dehydratase
GE073_RS17345	COG1760	l-serine dehydratase
GE073_RS17390	COG1082	Xylose isomerase domain protein TIM barrel
GE073_RS17400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GE073_RS17420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS17420	COG2207	Transcriptional regulator
GE073_RS17425	COG0778	Nitroreductase
GE073_RS17430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GE073_RS17435	COG3481	metal-dependent phosphohydrolase, HD sub domain
GE073_RS17445	COG0778	Nitroreductase
GE073_RS17450	COG1846	Transcriptional regulator
GE073_RS17455	COG0829	nickel cation binding
GE073_RS17460	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GE073_RS17475	COG0832	Belongs to the urease beta subunit family
GE073_RS17480	COG0831	urea catabolic process
GE073_RS17490	COG0745	RESPONSE REGULATOR receiver
GE073_RS17500	COG0129	dihydroxy-acid dehydratase activity
GE073_RS17510	COG1595	DNA-templated transcription, initiation
GE073_RS17520	COG0628	permease
GE073_RS17525	COG0840	transmembrane signaling receptor activity
GE073_RS17530	COG0768	penicillin binding
GE073_RS17535	COG0840	transmembrane signaling receptor activity
GE073_RS17540	COG0840	transmembrane signaling receptor activity
GE073_RS17545	COG0826	peptidase U32
GE073_RS17550	COG0826	peptidase U32
GE073_RS17555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GE073_RS17560	COG3906	Belongs to the UPF0473 family
GE073_RS17570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GE073_RS17575	COG4472	Bacterial protein of unknown function (DUF965)
GE073_RS17585	COG0628	permease
GE073_RS17600	COG1104	cysteine desulfurase activity
GE073_RS17605	COG1959	2 iron, 2 sulfur cluster binding
GE073_RS17610	COG0482	sulfurtransferase activity
GE073_RS17630	COG1253	flavin adenine dinucleotide binding
GE073_RS17640	COG1309	transcriptional regulator
GE073_RS17645	COG1914	H( )-stimulated, divalent metal cation uptake system
GE073_RS17650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GE073_RS17660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GE073_RS17665	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GE073_RS17670	COG0124	histidyl-tRNA synthetase
GE073_RS17680	COG1490	D-aminoacyl-tRNA deacylase activity
GE073_RS17685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GE073_RS17695	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GE073_RS17700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GE073_RS17700	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GE073_RS17710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GE073_RS17715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GE073_RS17715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GE073_RS17725	COG2244	polysaccharide biosynthetic process
GE073_RS17730	COG2323	membrane
GE073_RS17755	COG1862	Preprotein translocase
GE073_RS17770	COG2385	sporulation resulting in formation of a cellular spore
GE073_RS17770	COG2385	sporulation resulting in formation of a cellular spore
GE073_RS17780	COG2255	four-way junction helicase activity
GE073_RS17785	COG0632	four-way junction helicase activity
GE073_RS17790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GE073_RS17810	COG0077	Prephenate dehydratase
GE073_RS17815	COG0083	homoserine kinase activity
GE073_RS17820	COG0460	homoserine dehydrogenase
GE073_RS17825	COG4492	Belongs to the UPF0735 family
GE073_RS17830	COG2890	protein-(glutamine-N5) methyltransferase activity
GE073_RS17835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GE073_RS17845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GE073_RS17850	COG2868	ribosomal protein
GE073_RS17855	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GE073_RS17865	COG1994	Peptidase M50
GE073_RS17875	COG0772	Belongs to the SEDS family
GE073_RS17880	COG2894	cell division
GE073_RS17885	COG0850	regulation of cytokinetic process
GE073_RS17895	COG1792	Involved in formation and maintenance of cell shape
GE073_RS17900	COG1077	Cell shape determining protein MreB Mrl
GE073_RS17905	COG2003	Belongs to the UPF0758 family
GE073_RS17910	COG0424	maF-like protein
GE073_RS17925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GE073_RS17930	COG0285	dihydrofolate synthase activity
GE073_RS17935	COG0525	valine-tRNA ligase activity
GE073_RS17940	COG1388	LysM domain
GE073_RS17940	COG1388	LysM domain
GE073_RS17945	COG0564	pseudouridine synthase activity
GE073_RS17950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GE073_RS17955	COG0113	porphobilinogen synthase activity
GE073_RS17970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GE073_RS17970	COG1648	precorrin-2 dehydrogenase activity
GE073_RS17975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GE073_RS17985	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GE073_RS17995	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GE073_RS18005	COG1067	ATP-dependent peptidase activity
GE073_RS18005	COG0470	DNA polymerase III
GE073_RS18020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GE073_RS18025	COG0740	serine-type endopeptidase activity
GE073_RS18030	COG0544	peptidyl-prolyl cis-trans isomerase activity
GE073_RS18050	COG2390	Transcriptional regulator
GE073_RS18055	COG1295	ribonuclease BN
GE073_RS18070	COG0367	asparagine synthase
GE073_RS18075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GE073_RS18080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GE073_RS18090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GE073_RS18110	COG0697	spore germination
GE073_RS18125	COG1304	FMN binding
GE073_RS18140	COG1349	DNA-binding transcription factor activity
GE073_RS18145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GE073_RS18155	COG0514	ATP-dependent DNA helicase (RecQ)
GE073_RS18165	COG4133	protoheme IX ABC transporter activity
GE073_RS18185	COG0538	isocitrate dehydrogenase activity
GE073_RS18190	COG0372	Belongs to the citrate synthase family
GE073_RS18200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GE073_RS18210	COG0824	Thioesterase
GE073_RS18220	COG0825	malonyl-CoA metabolic process
GE073_RS18225	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GE073_RS18235	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GE073_RS18275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE073_RS18300	COG4109	DRTGG domain
GE073_RS18315	COG0395	ABC-type sugar transport system, permease component
GE073_RS18320	COG4209	transmembrane transport
GE073_RS18330	COG4753	response regulator
GE073_RS18330	COG2207	Transcriptional regulator
GE073_RS18335	COG3275	phosphorelay sensor kinase activity
GE073_RS18370	COG2884	Cell division ATP-binding protein ftsE
GE073_RS18375	COG4172	Belongs to the ABC transporter superfamily
GE073_RS18385	COG0601	transmembrane transport
GE073_RS18395	COG0583	DNA-binding transcription factor activity
GE073_RS18410	COG3693	PFAM glycoside hydrolase, family 10
GE073_RS18415	COG3679	Belongs to the UPF0342 family
GE073_RS18425	COG1361	Conserved repeat domain
GE073_RS18445	COG3279	Response regulator of the LytR AlgR family
GE073_RS18450	COG2972	Histidine kinase
GE073_RS18450	COG0745	RESPONSE REGULATOR receiver
GE073_RS18455	COG0189	ligase activity
GE073_RS18460	COG0189	ligase activity
GE073_RS18465	COG0189	ligase activity
GE073_RS18490	COG5002	protein histidine kinase activity
GE073_RS18495	COG3546	catalase activity
GE073_RS18515	COG5522	Integral membrane protein (intg_mem_TP0381)
GE073_RS18520	COG0628	permease
GE073_RS18525	COG1253	flavin adenine dinucleotide binding
GE073_RS18530	COG0535	radical SAM domain protein
GE073_RS18540	COG0737	Belongs to the 5'-nucleotidase family
GE073_RS18550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GE073_RS18555	COG0314	molybdopterin synthase activity
GE073_RS18560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GE073_RS18565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GE073_RS18610	COG3299	homolog of phage Mu protein gp47
GE073_RS18695	COG0719	Fe-S assembly protein
GE073_RS18700	COG0822	iron-sulfur transferase activity
GE073_RS18705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GE073_RS18710	COG0719	Fe-S assembly protein
GE073_RS18715	COG0396	ATPase activity
GE073_RS18725	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GE073_RS18730	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GE073_RS18740	COG3377	Domain of unknown function (DUF1805)
GE073_RS18745	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GE073_RS18750	COG1653	transport
GE073_RS18755	COG4209	transmembrane transport
GE073_RS18760	COG0395	ABC-type sugar transport system, permease component
GE073_RS18765	COG2207	Transcriptional regulator
GE073_RS18770	COG1609	Transcriptional regulator
GE073_RS18775	COG1904	glucuronate isomerase
GE073_RS18790	COG2363	Small membrane protein
GE073_RS18795	COG2718	Belongs to the UPF0229 family
GE073_RS18805	COG1657	PFAM Prenyltransferase squalene oxidase
GE073_RS18830	COG3250	beta-galactosidase activity
GE073_RS18835	COG2207	Transcriptional regulator
GE073_RS18835	COG4753	response regulator
GE073_RS18840	COG2972	Histidine kinase
GE073_RS18855	COG0395	ABC-type sugar transport system, permease component
GE073_RS18860	COG1175	transmembrane transport
GE073_RS18870	COG3940	Belongs to the glycosyl hydrolase 43 family
GE073_RS18890	COG2514	catechol 2,3-dioxygenase activity
GE073_RS18895	COG0531	amino acid
GE073_RS18905	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GE073_RS18915	COG1309	transcriptional regulator
GE073_RS18930	COG2719	SpoVR family
GE073_RS18990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE073_RS19005	COG0395	ABC-type sugar transport system, permease component
GE073_RS19015	COG1653	transport
GE073_RS19020	COG3459	Glycosyltransferase 36 associated
GE073_RS19025	COG1609	Transcriptional regulator
GE073_RS19030	COG0697	spore germination
GE073_RS19065	COG2766	serine protein kinase
GE073_RS19085	COG2182	Extracellular solute-binding protein
GE073_RS19100	COG2972	Histidine kinase
GE073_RS19105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS19105	COG2207	Transcriptional regulator
GE073_RS19110	COG2002	toxin-antitoxin pair type II binding
GE073_RS19120	COG0745	RESPONSE REGULATOR receiver
GE073_RS19135	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GE073_RS19140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GE073_RS19150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GE073_RS19155	COG3850	Histidine kinase
GE073_RS19155	COG5002	protein histidine kinase activity
GE073_RS19160	COG0745	RESPONSE REGULATOR receiver
GE073_RS19165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE073_RS19175	COG2197	response regulator
GE073_RS19180	COG4585	Histidine kinase
GE073_RS19185	COG4758	membrane
GE073_RS19190	COG1522	sequence-specific DNA binding
GE073_RS19195	COG3584	3D domain protein
GE073_RS19200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GE073_RS19215	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GE073_RS19220	COG0626	cystathionine gamma-synthase activity
GE073_RS19225	COG0626	cystathionine gamma-synthase activity
GE073_RS19230	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GE073_RS19235	COG2233	PERMEase
GE073_RS19245	COG0598	Magnesium transport protein CorA
GE073_RS19275	COG2259	Doxx family
GE073_RS19280	COG1733	regulation of RNA biosynthetic process
GE073_RS19290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GE073_RS19295	COG1053	succinate dehydrogenase
GE073_RS19300	COG2009	succinate dehydrogenase
GE073_RS19305	COG0583	DNA-binding transcription factor activity
GE073_RS19310	COG0569	domain protein
GE073_RS19315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GE073_RS19325	COG0322	excinuclease ABC activity
GE073_RS19340	COG4208	sulfate ABC transporter
GE073_RS19345	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GE073_RS19350	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GE073_RS19355	COG1484	DNA-dependent DNA replication
GE073_RS19375	COG0395	ABC-type sugar transport system, permease component
GE073_RS19380	COG1175	transmembrane transport
GE073_RS19390	COG3275	phosphorelay sensor kinase activity
GE073_RS19400	COG1252	NADH dehydrogenase
GE073_RS19405	COG0492	ferredoxin-NADP+ reductase activity
GE073_RS19415	COG0189	ligase activity
GE073_RS19425	COG0577	efflux transmembrane transporter activity
GE073_RS19430	COG1136	(ABC) transporter
GE073_RS19435	COG5002	protein histidine kinase activity
GE073_RS19440	COG0745	RESPONSE REGULATOR receiver
GE073_RS19450	COG1309	transcriptional regulator
GE073_RS19455	COG2076	Multidrug Resistance protein
GE073_RS19460	COG2076	Multidrug Resistance protein
GE073_RS19465	COG0316	Belongs to the HesB IscA family
GE073_RS19475	COG4977	sequence-specific DNA binding
GE073_RS19475	COG1917	Cupin 2, conserved barrel domain protein
GE073_RS19480	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GE073_RS19485	COG1252	NADH dehydrogenase
GE073_RS19490	COG4844	belongs to the
GE073_RS19495	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GE073_RS19500	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS19510	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GE073_RS19515	COG1612	heme a metabolic process
GE073_RS19520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE073_RS19530	COG2244	polysaccharide biosynthetic process
GE073_RS19540	COG2839	Protein conserved in bacteria
GE073_RS19545	COG0561	phosphatase activity
GE073_RS19550	COG1215	transferase activity, transferring glycosyl groups
GE073_RS19555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GE073_RS19560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GE073_RS19560	COG1321	iron dependent repressor
GE073_RS19565	COG1121	(ABC) transporter
GE073_RS19570	COG0803	Belongs to the bacterial solute-binding protein 9 family
GE073_RS19610	COG0109	protoheme IX farnesyltransferase activity
GE073_RS19615	COG3773	Cell wall hydrolase
GE073_RS19630	COG1988	membrane-bound metal-dependent
GE073_RS19640	COG0180	Tryptophanyl-tRNA synthetase
GE073_RS19645	COG0701	Predicted permease
GE073_RS19665	COG0840	transmembrane signaling receptor activity
GE073_RS19675	COG3584	3D domain protein
GE073_RS19675	COG1388	LysM domain
GE073_RS19680	COG2340	Cysteine-rich secretory protein family
GE073_RS19690	COG1396	sequence-specific DNA binding
GE073_RS19715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GE073_RS19725	COG0662	Cupin 2, conserved barrel domain protein
GE073_RS19725	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GE073_RS19735	COG0110	maltose O-acetyltransferase activity
GE073_RS19740	COG0438	transferase activity, transferring glycosyl groups
GE073_RS19745	COG0297	glycogen (starch) synthase activity
GE073_RS19760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE073_RS19765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GE073_RS19770	COG5039	Polysaccharide pyruvyl transferase
GE073_RS19785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GE073_RS19790	COG0489	protein tyrosine kinase activity
GE073_RS19795	COG3944	biosynthesis protein
GE073_RS19820	COG0095	Lipoate-protein ligase
GE073_RS19830	COG4608	Belongs to the ABC transporter superfamily
GE073_RS19835	COG0444	Belongs to the ABC transporter superfamily
GE073_RS19840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE073_RS19845	COG0601	transmembrane transport
GE073_RS19855	COG1363	Peptidase, m42
GE073_RS19860	COG2972	Histidine kinase
GE073_RS19865	COG4753	response regulator
GE073_RS19865	COG2207	Transcriptional regulator
GE073_RS19870	COG1653	transport
GE073_RS19875	COG0395	ABC-type sugar transport system, permease component
GE073_RS19880	COG4209	transmembrane transport
GE073_RS19915	COG3091	SprT-like family
GE073_RS19930	COG2183	response to ionizing radiation
GE073_RS19935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE073_RS19945	COG0586	Pfam SNARE associated Golgi protein
GE073_RS19975	COG4251	negative regulation of phosphorylation
GE073_RS19975	COG2203	Gaf domain
GE073_RS19975	COG5001	Diguanylate cyclase
GE073_RS19975	COG3706	GGDEF domain
GE073_RS19990	COG2267	carboxylic ester hydrolase activity
GE073_RS20010	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GE073_RS20015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GE073_RS20020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GE073_RS20045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE073_RS20050	COG2814	Major facilitator Superfamily
GE073_RS20060	COG1366	Belongs to the anti-sigma-factor antagonist family
GE073_RS20065	COG2172	sigma factor antagonist activity
GE073_RS20070	COG1191	sigma factor activity
GE073_RS20080	COG1131	(ABC) transporter
GE073_RS20090	COG1595	DNA-templated transcription, initiation
GE073_RS20110	COG2208	phosphoserine phosphatase activity
GE073_RS20135	COG0024	Methionine aminopeptidase
GE073_RS20140	COG1126	abc transporter atp-binding protein
GE073_RS20145	COG0765	amino acid transport
GE073_RS20150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE073_RS20155	COG2234	aminopeptidase activity
GE073_RS20165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GE073_RS20175	COG1272	protein, Hemolysin III
GE073_RS20185	COG1741	Belongs to the pirin family
GE073_RS20195	COG0517	IMP dehydrogenase activity
GE073_RS20195	COG1125	glycine betaine transport
GE073_RS20200	COG1174	glycine betaine transport
GE073_RS20205	COG1732	Glycine betaine
GE073_RS20215	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GE073_RS20220	COG2814	Major facilitator Superfamily
GE073_RS20225	COG0745	RESPONSE REGULATOR receiver
GE073_RS20255	COG2368	4-hydroxyphenylacetate
GE073_RS20275	COG1695	Transcriptional regulator
GE073_RS20290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GE073_RS20315	COG0431	NADPH-dependent FMN reductase
GE073_RS20330	COG2059	Chromate
GE073_RS20335	COG0405	Gamma-glutamyltransferase
GE073_RS20350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE073_RS20355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GE073_RS20360	COG2351	hydroxyisourate hydrolase activity
GE073_RS20365	COG3648	Uricase
GE073_RS20365	COG3195	allantoin biosynthetic process
GE073_RS20375	COG2080	2 iron, 2 sulfur cluster binding
GE073_RS20380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GE073_RS20385	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GE073_RS20390	COG1079	Belongs to the binding-protein-dependent transport system permease family
GE073_RS20395	COG4603	Belongs to the binding-protein-dependent transport system permease family
GE073_RS20400	COG3845	ABC transporter
GE073_RS20415	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GE073_RS20420	COG2508	Transcriptional regulator
GE073_RS20425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GE073_RS20440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GE073_RS20445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GE073_RS20450	COG1780	Probably involved in ribonucleotide reductase function
GE073_RS20460	COG2911	Protein conserved in bacteria
GE073_RS20460	COG1361	Conserved repeat domain
GE073_RS20460	COG3266	domain, Protein
GE073_RS20465	COG1511	domain protein
GE073_RS20470	COG1309	transcriptional regulator
GE073_RS20475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GE073_RS20475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GE073_RS20490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GE073_RS20495	COG5416	Lipopolysaccharide assembly protein A domain
GE073_RS20500	COG5002	protein histidine kinase activity
GE073_RS20500	COG0784	Response regulator, receiver
GE073_RS20505	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS20510	COG2017	converts alpha-aldose to the beta-anomer
GE073_RS20515	COG2409	Drug exporters of the RND superfamily
GE073_RS20515	COG1033	growth of symbiont in host cell
GE073_RS20525	COG2378	regulation of single-species biofilm formation
GE073_RS20585	COG1132	(ABC) transporter
GE073_RS20590	COG1132	(ABC) transporter
GE073_RS20605	COG0477	Major facilitator Superfamily
GE073_RS20620	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GE073_RS20625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GE073_RS20635	COG0095	Lipoate-protein ligase
GE073_RS20640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GE073_RS20770	COG1472	Belongs to the glycosyl hydrolase 3 family
GE073_RS20780	COG4474	Belongs to the UPF0398 family
GE073_RS20790	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE073_RS20790	COG3103	Sh3 type 3 domain protein
GE073_RS20790	COG4991	sh3 domain protein
GE073_RS20795	COG4841	protein insertion into membrane
GE073_RS20830	COG0791	NLP P60 protein
GE073_RS20835	COG4948	Mandelate Racemase Muconate Lactonizing
GE073_RS20840	COG1619	proteins homologs of microcin C7 resistance protein MccF
GE073_RS20845	COG4166	transmembrane transport
GE073_RS20850	COG0444	Belongs to the ABC transporter superfamily
GE073_RS20855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE073_RS20860	COG0601	transmembrane transport
GE073_RS20865	COG2362	D-Aminopeptidase
GE073_RS20875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE073_RS20880	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GE073_RS20880	COG2199	diguanylate cyclase activity
GE073_RS20890	COG0395	ABC-type sugar transport system, permease component
GE073_RS20895	COG1175	transmembrane transport
GE073_RS20905	COG4753	response regulator
GE073_RS20905	COG2207	Transcriptional regulator
GE073_RS20910	COG2972	Histidine kinase
GE073_RS20915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GE073_RS20920	COG0824	Thioesterase
GE073_RS20925	COG2746	aminoglycoside 3-N-acetyltransferase activity
GE073_RS20930	COG0640	Transcriptional regulator
GE073_RS20935	COG3708	Transcriptional regulator
GE073_RS20935	COG2207	Transcriptional regulator
GE073_RS20965	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GE073_RS20965	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GE073_RS20985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GE073_RS21000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GE073_RS21005	COG0823	Involved in the tonB-independent uptake of proteins
GE073_RS21015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GE073_RS21025	COG0346	lactoylglutathione lyase activity
GE073_RS21045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE073_RS21110	COG1175	transmembrane transport
GE073_RS21120	COG1609	Transcriptional regulator
GE073_RS21135	COG1124	(ABC) transporter
GE073_RS21140	COG0444	Belongs to the ABC transporter superfamily
GE073_RS21145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE073_RS21150	COG0601	transmembrane transport
GE073_RS21155	COG0747	negative chemotaxis
GE073_RS21185	COG0582	viral genome integration into host DNA
GE073_RS21240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GE073_RS21245	COG1597	lipid kinase activity
GE073_RS21255	COG4496	protein, YerC YecD
GE073_RS21265	COG0306	phosphate transporter
GE073_RS21270	COG1392	Phosphate transport regulator
GE073_RS21275	COG1470	cell adhesion involved in biofilm formation
GE073_RS21295	COG1073	alpha beta
GE073_RS21300	COG1733	regulation of RNA biosynthetic process
GE073_RS21305	COG5002	protein histidine kinase activity
GE073_RS21310	COG0745	RESPONSE REGULATOR receiver
GE073_RS21325	COG1653	transport
GE073_RS21340	COG0151	Belongs to the GarS family
GE073_RS21350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GE073_RS21355	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GE073_RS21360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GE073_RS21365	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GE073_RS21370	COG0047	phosphoribosylformylglycinamidine synthase activity
GE073_RS21375	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GE073_RS21380	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GE073_RS21385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GE073_RS21390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GE073_RS21395	COG0778	Nitroreductase
GE073_RS21415	COG1404	Belongs to the peptidase S8 family
GE073_RS21425	COG2252	PERMEase
GE073_RS21430	COG0477	Major facilitator Superfamily
GE073_RS21440	COG0252	asparaginase activity
GE073_RS21485	COG2176	DNA-directed DNA polymerase activity
GE073_RS21510	COG1361	Conserved repeat domain
GE073_RS21510	COG2911	Protein conserved in bacteria
GE073_RS21510	COG3266	domain, Protein
GE073_RS21515	COG1361	Conserved repeat domain
GE073_RS21535	COG1674	ftsk spoiiie
GE073_RS21590	COG4974	Belongs to the 'phage' integrase family
GE073_RS21595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GE073_RS21595	COG0519	Catalyzes the synthesis of GMP from XMP
GE073_RS21600	COG1305	Transglutaminase-like
GE073_RS21610	COG0714	Associated with various cellular activities
GE073_RS21625	COG0584	glycerophosphoryl diester phosphodiesterase
GE073_RS21630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GE073_RS21650	COG1316	TRANSCRIPTIONal
GE073_RS21665	COG4122	O-methyltransferase activity
GE073_RS21670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GE073_RS21680	COG0583	DNA-binding transcription factor activity
GE073_RS21700	COG0572	uridine kinase
GE073_RS21715	COG1122	ATPase activity
GE073_RS21745	COG0789	Transcriptional regulator
GE073_RS21775	COG4753	response regulator
GE073_RS21775	COG4753	response regulator
GE073_RS21775	COG2207	Transcriptional regulator
GE073_RS21775	COG2207	Transcriptional regulator
GE073_RS21780	COG2972	Histidine kinase
GE073_RS21790	COG0395	ABC-type sugar transport system, permease component
GE073_RS21795	COG4209	transmembrane transport
GE073_RS21800	COG0572	uridine kinase
GE073_RS21810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GE073_RS21815	COG3290	protein histidine kinase activity
GE073_RS21830	COG1301	dicarboxylic acid transport
GE073_RS21840	COG0477	Major facilitator Superfamily
GE073_RS21845	COG1846	Transcriptional regulator
GE073_RS21850	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GE073_RS21860	COG0483	inositol monophosphate 1-phosphatase activity
GE073_RS21865	COG0730	response to heat
GE073_RS21870	COG4294	response to UV
GE073_RS21880	COG1181	Belongs to the D-alanine--D-alanine ligase family
GE073_RS21900	COG1414	Transcriptional regulator
GE073_RS21910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GE073_RS21915	COG0302	gtp cyclohydrolase
GE073_RS21925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GE073_RS21930	COG0328	RNA-DNA hybrid ribonuclease activity
GE073_RS21945	COG0456	acetyltransferase
GE073_RS21965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE073_RS21975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GE073_RS21980	COG0432	Pfam Uncharacterised protein family UPF0047
GE073_RS21985	COG0840	transmembrane signaling receptor activity
GE073_RS21990	COG0783	Belongs to the Dps family
GE073_RS22010	COG0179	Fumarylacetoacetate (FAA) hydrolase
GE073_RS22015	COG0488	(ABC) transporter
GE073_RS22035	COG0114	fumarate hydratase activity
GE073_RS22040	COG0800	Aldolase
GE073_RS22045	COG0024	Methionine aminopeptidase
GE073_RS22075	COG4753	response regulator
GE073_RS22075	COG2207	Transcriptional regulator
GE073_RS22080	COG3275	phosphorelay sensor kinase activity
GE073_RS22090	COG0395	ABC-type sugar transport system, permease component
GE073_RS22095	COG4209	transmembrane transport
GE073_RS22100	COG2207	Transcriptional regulator
GE073_RS22105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS22110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS22120	COG1501	Belongs to the glycosyl hydrolase 31 family
GE073_RS22135	COG2814	Major facilitator Superfamily
GE073_RS22140	COG1472	Belongs to the glycosyl hydrolase 3 family
GE073_RS22155	COG1428	Deoxynucleoside kinase
GE073_RS22160	COG1428	Deoxynucleoside kinase
GE073_RS22165	COG0716	FMN binding
GE073_RS22180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GE073_RS22190	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GE073_RS22195	COG0517	IMP dehydrogenase activity
GE073_RS22200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GE073_RS22200	COG0574	Belongs to the PEP-utilizing enzyme family
GE073_RS22210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GE073_RS22215	COG1494	fructose-1,6-bisphosphatase
GE073_RS22220	COG0667	Aldo Keto reductase
GE073_RS22230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GE073_RS22240	COG0398	Pfam SNARE associated Golgi protein
GE073_RS22255	COG4191	Histidine kinase
GE073_RS22280	COG0714	Associated with various cellular activities
GE073_RS22300	COG0589	response to stress
GE073_RS22305	COG2205	protein histidine kinase activity
GE073_RS22305	COG0784	Response regulator, receiver
GE073_RS22305	COG2198	Histidine kinase
GE073_RS22325	COG0454	-acetyltransferase
GE073_RS22330	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS22335	COG0492	ferredoxin-NADP+ reductase activity
GE073_RS22340	COG1876	peptidase activity
GE073_RS22350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GE073_RS22360	COG0038	chloride channel
GE073_RS22370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE073_RS22375	COG3409	Peptidoglycan-binding domain 1 protein
GE073_RS22375	COG0793	Belongs to the peptidase S41A family
GE073_RS22385	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GE073_RS22390	COG1196	nuclear chromosome segregation
GE073_RS22390	COG0741	lytic transglycosylase activity
GE073_RS22390	COG0739	heme binding
GE073_RS22395	COG2177	Part of the ABC transporter FtsEX involved in
GE073_RS22400	COG2884	Cell division ATP-binding protein ftsE
GE073_RS22410	COG1595	DNA-templated transcription, initiation
GE073_RS22420	COG0723	plastoquinol--plastocyanin reductase activity
GE073_RS22420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE073_RS22425	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GE073_RS22435	COG0640	Transcriptional regulator
GE073_RS22455	COG1131	(ABC) transporter
GE073_RS22460	COG4585	Histidine kinase
GE073_RS22470	COG2720	vancomycin resistance protein
GE073_RS22490	COG0165	Argininosuccinate lyase
GE073_RS22495	COG0137	argininosuccinate synthase activity
GE073_RS22500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GE073_RS22510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GE073_RS22515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GE073_RS22525	COG2076	Multidrug Resistance protein
GE073_RS22545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE073_RS22555	COG0653	protein targeting
GE073_RS22565	COG1278	Cold shock
GE073_RS22570	COG0463	Glycosyl transferase, family 2
GE073_RS22570	COG0457	Tetratricopeptide repeat
GE073_RS22585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GE073_RS22590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GE073_RS22595	COG3475	LICD family
GE073_RS22605	COG0500	methyltransferase
GE073_RS22630	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GE073_RS22640	COG0463	Glycosyl transferase, family 2
GE073_RS22640	COG0457	Tetratricopeptide repeat
GE073_RS22645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GE073_RS22650	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GE073_RS22655	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GE073_RS22665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GE073_RS22670	COG1256	bacterial-type flagellum assembly
GE073_RS22670	COG4786	Flagellar basal body rod
GE073_RS22695	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GE073_RS22730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GE073_RS22765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GE073_RS22785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GE073_RS22790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GE073_RS22810	COG4786	Flagellar basal body rod
GE073_RS22820	COG1609	Transcriptional regulator
GE073_RS22825	COG0739	heme binding
GE073_RS22830	COG2385	sporulation resulting in formation of a cellular spore
GE073_RS22835	COG5002	protein histidine kinase activity
GE073_RS22840	COG0745	RESPONSE REGULATOR receiver
GE073_RS22845	COG0577	efflux transmembrane transporter activity
GE073_RS22845	COG1136	(ABC) transporter
GE073_RS22850	COG1136	(ABC) transporter
GE073_RS22860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GE073_RS22870	COG1404	Belongs to the peptidase S8 family
GE073_RS22885	COG4464	protein tyrosine phosphatase activity
GE073_RS22890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GE073_RS22895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GE073_RS22900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GE073_RS22905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GE073_RS22910	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GE073_RS22915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GE073_RS22920	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GE073_RS22925	COG0356	it plays a direct role in the translocation of protons across the membrane
GE073_RS22940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GE073_RS22945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GE073_RS22950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GE073_RS22955	COG4475	Protein of unknown function (DUF436)
GE073_RS22960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GE073_RS22965	COG1971	Probably functions as a manganese efflux pump
GE073_RS22970	COG0009	L-threonylcarbamoyladenylate synthase
GE073_RS22980	COG2890	protein-(glutamine-N5) methyltransferase activity
GE073_RS22985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GE073_RS22990	COG0012	GTP binding
GE073_RS23025	COG0402	S-adenosylhomocysteine deaminase activity
GE073_RS23035	COG3118	belongs to the thioredoxin family
GE073_RS23045	COG0656	L-ascorbic acid biosynthetic process
GE073_RS23070	COG1175	transmembrane transport
GE073_RS23075	COG4753	response regulator
GE073_RS23075	COG2207	Transcriptional regulator
GE073_RS23080	COG2972	Histidine kinase
GE073_RS23095	COG1801	Protein of unknown function DUF72
GE073_RS23120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GE073_RS23145	COG1215	transferase activity, transferring glycosyl groups
GE073_RS23180	COG1091	dTDP-4-dehydrorhamnose reductase activity
GE073_RS23195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GE073_RS23200	COG0463	Glycosyl transferase, family 2
GE073_RS23215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GE073_RS23220	COG0386	Belongs to the glutathione peroxidase family
GE073_RS23225	COG1846	Transcriptional regulator
GE073_RS23230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GE073_RS23235	COG4846	Membrane protein involved in cytochrome C biogenesis
GE073_RS23240	COG0693	protein deglycase activity
GE073_RS23250	COG4876	unkown
GE073_RS23260	COG0463	Glycosyl transferase, family 2
GE073_RS23275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE073_RS23280	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GE073_RS23315	COG5002	protein histidine kinase activity
GE073_RS23320	COG1132	(ABC) transporter
GE073_RS23325	COG2814	Major facilitator Superfamily
GE073_RS23330	COG0673	inositol 2-dehydrogenase activity
GE073_RS23335	COG0745	RESPONSE REGULATOR receiver
GE073_RS23340	COG1132	(ABC) transporter
GE073_RS23350	COG1201	RNA secondary structure unwinding
GE073_RS23350	COG1201	RNA secondary structure unwinding
GE073_RS23365	COG1119	ATPase activity
GE073_RS23375	COG0706	membrane insertase activity
GE073_RS23400	COG1126	abc transporter atp-binding protein
GE073_RS23405	COG0765	amino acid transport
GE073_RS23410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE073_RS23420	COG1132	(ABC) transporter
GE073_RS23425	COG1132	(ABC) transporter
GE073_RS23435	COG1956	GAF domain-containing protein
GE073_RS23440	COG3739	integral membrane protein
GE073_RS23450	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GE073_RS23470	COG1522	sequence-specific DNA binding
GE073_RS23475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GE073_RS23495	COG4209	transmembrane transport
GE073_RS23500	COG0395	ABC-type sugar transport system, permease component
GE073_RS23510	COG2207	Transcriptional regulator
GE073_RS23545	COG3237	CsbD-like
GE073_RS23550	COG1252	NADH dehydrogenase
GE073_RS23560	COG3173	Aminoglycoside phosphotransferase
GE073_RS23595	COG4326	sporulation control protein
GE073_RS23605	COG0463	Glycosyl transferase, family 2
GE073_RS23620	COG1562	ergosterol biosynthetic process
GE073_RS23635	COG1199	ATP-dependent helicase activity
GE073_RS23640	COG2267	carboxylic ester hydrolase activity
GE073_RS23645	COG3706	GGDEF domain
GE073_RS23660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GE073_RS23665	COG4297	protein containing double-stranded beta helix domain
GE073_RS23695	COG2271	Major facilitator Superfamily
GE073_RS23700	COG4335	DNA alkylation repair
GE073_RS23710	COG2770	Histidine kinase
GE073_RS23710	COG3437	response regulator, receiver
GE073_RS23725	COG2211	Major facilitator Superfamily
GE073_RS23730	COG0753	catalase activity
GE073_RS23750	COG0586	Pfam SNARE associated Golgi protein
GE073_RS23770	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GE073_RS23775	COG1012	belongs to the aldehyde dehydrogenase family
GE073_RS23780	COG0506	proline dehydrogenase activity
GE073_RS23785	COG3290	protein histidine kinase activity
GE073_RS23785	COG3829	transcription factor binding
GE073_RS23790	COG0662	Cupin 2, conserved barrel domain protein
GE073_RS23790	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GE073_RS23795	COG0438	transferase activity, transferring glycosyl groups
GE073_RS23805	COG2195	Cleaves the N-terminal amino acid of tripeptides
GE073_RS23815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GE073_RS23820	COG0583	DNA-binding transcription factor activity
GE073_RS23825	COG0693	protein deglycase activity
GE073_RS23825	COG0753	catalase activity
GE073_RS23835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE073_RS23840	COG2197	response regulator
GE073_RS23865	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GE073_RS23870	COG2233	PERMEase
GE073_RS23875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GE073_RS23880	COG2271	Major facilitator Superfamily
GE073_RS23885	COG0277	FAD linked oxidase domain protein
GE073_RS23895	COG2249	NAD(P)H dehydrogenase (quinone) activity
GE073_RS23900	COG3693	PFAM glycoside hydrolase, family 10
GE073_RS23905	COG2094	Belongs to the DNA glycosylase MPG family
GE073_RS23915	COG2323	membrane
GE073_RS23920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GE073_RS23930	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GE073_RS23935	COG1230	cation diffusion facilitator family transporter
GE073_RS23940	COG1733	regulation of RNA biosynthetic process
GE073_RS23945	COG0667	Aldo Keto reductase
GE073_RS23960	COG2365	Tyrosine phosphatase family
GE073_RS23995	COG0714	Associated with various cellular activities
GE073_RS24000	COG1418	mRNA catabolic process
GE073_RS24005	COG2321	neutral zinc metallopeptidase
GE073_RS24015	COG5278	phosphoserine phosphatase activity
GE073_RS24015	COG0840	transmembrane signaling receptor activity
GE073_RS24025	COG0513	Belongs to the DEAD box helicase family
GE073_RS24030	COG2814	Major facilitator Superfamily
GE073_RS24035	COG0789	Transcriptional regulator
GE073_RS24040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE073_RS24045	COG1597	lipid kinase activity
GE073_RS24050	COG4989	oxidoreductase activity
GE073_RS24055	COG4565	transcriptional regulatory protein
GE073_RS24060	COG3290	protein histidine kinase activity
GE073_RS24065	COG3181	Tripartite tricarboxylate transporter family receptor
GE073_RS24120	COG0745	RESPONSE REGULATOR receiver
GE073_RS24125	COG5002	protein histidine kinase activity
GE073_RS24130	COG3693	PFAM glycoside hydrolase, family 10
GE073_RS24145	COG0673	inositol 2-dehydrogenase activity
GE073_RS24160	COG3682	Transcriptional regulator
GE073_RS24175	COG2207	Transcriptional regulator
GE073_RS24190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE073_RS24205	COG1309	transcriptional regulator
GE073_RS24210	COG2814	Major facilitator Superfamily
GE073_RS24220	COG0745	RESPONSE REGULATOR receiver
GE073_RS24235	COG2205	protein histidine kinase activity
GE073_RS24245	COG3693	PFAM glycoside hydrolase, family 10
GE073_RS24255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS24260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE073_RS24265	COG1120	ATPase activity
GE073_RS24285	COG0395	ABC-type sugar transport system, permease component
GE073_RS24290	COG4209	transmembrane transport
GE073_RS24295	COG1653	transport
GE073_RS24300	COG2207	Transcriptional regulator
GE073_RS24310	COG1940	carbohydrate kinase activity
GE073_RS24315	COG1940	carbohydrate kinase activity
GE073_RS24320	COG0778	Nitroreductase
GE073_RS24325	COG0110	maltose O-acetyltransferase activity
GE073_RS24340	COG0322	excinuclease ABC activity
GE073_RS24380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE073_RS24405	COG0488	(ABC) transporter
GE073_RS24420	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GE073_RS24425	COG0189	ligase activity
GE073_RS24435	COG1733	regulation of RNA biosynthetic process
GE073_RS24440	COG2910	NAD(P)H-binding
GE073_RS24450	COG2205	protein histidine kinase activity
GE073_RS24470	COG1309	transcriptional regulator
GE073_RS24475	COG1028	Short-chain dehydrogenase reductase Sdr
GE073_RS24480	COG1250	3-hydroxyacyl-CoA dehydrogenase
GE073_RS24485	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GE073_RS24500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GE073_RS24505	COG4988	ABC transporter
GE073_RS24510	COG1294	oxidase, subunit
GE073_RS24515	COG1271	oxidase subunit
GE073_RS24530	COG4941	Belongs to the sigma-70 factor family
GE073_RS24550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE073_RS24560	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GE073_RS24565	COG4853	Protein conserved in bacteria
GE073_RS24575	COG5002	protein histidine kinase activity
GE073_RS24580	COG0745	RESPONSE REGULATOR receiver
GE073_RS24585	COG0739	heme binding
GE073_RS24595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GE073_RS24600	COG0305	Participates in initiation and elongation during chromosome replication
GE073_RS24605	COG0359	binds to the 23S rRNA
GE073_RS24610	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GE073_RS24625	COG1316	TRANSCRIPTIONal
GE073_RS24635	COG1253	flavin adenine dinucleotide binding
GE073_RS24640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GE073_RS24655	COG4191	Histidine kinase
GE073_RS24660	COG4191	Histidine kinase
GE073_RS24675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GE073_RS24680	COG3377	Domain of unknown function (DUF1805)
GE073_RS24685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE073_RS24735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GE073_RS24745	COG2323	membrane
GE073_RS24755	COG3949	Membrane
GE073_RS24800	COG3546	catalase activity
GE073_RS24825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GE073_RS24830	COG0629	single-stranded DNA binding
GE073_RS24835	COG0360	Binds together with S18 to 16S ribosomal RNA
GE073_RS24855	COG4481	Protein conserved in bacteria
GE073_RS24860	COG0668	transmembrane transport
GE073_RS24880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GE073_RS24885	COG1475	DNA binding
GE073_RS24890	COG1192	Involved in chromosome partitioning
GE073_RS24895	COG1475	DNA binding
GE073_RS24900	COG0357	Ribosomal RNA small subunit methyltransferase G
GE073_RS24905	COG0445	tRNA wobble uridine modification
GE073_RS24910	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GE073_RS24915	COG0706	membrane insertase activity
GE073_RS24920	COG0594	ribonuclease P activity
GE073_RS24925	COG0230	Belongs to the bacterial ribosomal protein bL34 family