locus-tag	class	description
EI981_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EI981_RS00010	COG0592	DNA-directed DNA polymerase activity
EI981_RS00015	COG2501	S4 domain
EI981_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EI981_RS00030	COG0187	DNA topoisomerase II activity
EI981_RS00035	COG0189	ligase activity
EI981_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EI981_RS00085	COG1982	Orn Lys Arg decarboxylase major
EI981_RS00095	COG3870	Protein conserved in bacteria
EI981_RS00100	COG1728	Protein conserved in bacteria
EI981_RS00105	COG0470	DNA polymerase III
EI981_RS00110	COG1774	PSP1 C-terminal conserved region
EI981_RS00115	COG4467	Involved in initiation control of chromosome replication
EI981_RS00120	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EI981_RS00125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EI981_RS00130	COG2002	toxin-antitoxin pair type II binding
EI981_RS00135	COG1078	dGTPase activity
EI981_RS00140	COG0084	hydrolase, TatD family'
EI981_RS00145	COG3584	3D domain protein
EI981_RS00145	COG3583	domain protein
EI981_RS00155	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EI981_RS00165	COG4466	Protein conserved in bacteria
EI981_RS00175	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EI981_RS00180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EI981_RS00185	COG2088	sporulation resulting in formation of a cellular spore
EI981_RS00190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EI981_RS00195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EI981_RS00220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EI981_RS00225	COG2002	toxin-antitoxin pair type II binding
EI981_RS00230	COG2244	polysaccharide biosynthetic process
EI981_RS00235	COG3956	TIGRFAM MazG family protein
EI981_RS00240	COG0776	regulation of translation
EI981_RS00245	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EI981_RS00265	COG1098	S1 RNA binding domain
EI981_RS00270	COG2208	phosphoserine phosphatase activity
EI981_RS00285	COG2304	oxidoreductase activity
EI981_RS00290	COG0515	serine threonine protein kinase
EI981_RS00295	COG0037	tRNA processing
EI981_RS00305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EI981_RS00310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EI981_RS00315	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EI981_RS00325	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EI981_RS00335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EI981_RS00340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EI981_RS00345	COG0512	Glutamine amidotransferase of anthranilate synthase
EI981_RS00350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EI981_RS00355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EI981_RS00360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EI981_RS00365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EI981_RS00370	COG1396	sequence-specific DNA binding
EI981_RS00375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EI981_RS00385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EI981_RS00415	COG0740	serine-type endopeptidase activity
EI981_RS00420	COG0517	IMP dehydrogenase activity
EI981_RS00420	COG0516	GMP reductase activity
EI981_RS00425	COG1686	Belongs to the peptidase S11 family
EI981_RS00440	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EI981_RS00455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EI981_RS00460	COG0590	tRNA wobble adenosine to inosine editing
EI981_RS00465	COG5002	protein histidine kinase activity
EI981_RS00470	COG1187	pseudouridine synthase activity
EI981_RS00475	COG1360	Flagellar Motor Protein
EI981_RS00480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EI981_RS00490	COG2154	pterin-4-alpha-carbinolamine dehydratase
EI981_RS00510	COG0791	NLP P60 protein
EI981_RS00535	COG0640	Transcriptional regulator
EI981_RS00540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EI981_RS00545	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EI981_RS00550	COG0010	Belongs to the arginase family
EI981_RS00560	COG0018	arginyl-trna synthetase
EI981_RS00565	COG1404	Belongs to the peptidase S8 family
EI981_RS00570	COG3343	RNA polymerase activity
EI981_RS00575	COG0504	CTP synthase activity
EI981_RS00580	COG2204	response regulator
EI981_RS00590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EI981_RS00595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EI981_RS00605	COG0254	rRNA binding
EI981_RS00615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EI981_RS00620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EI981_RS00660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EI981_RS00665	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EI981_RS00670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EI981_RS00750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI981_RS00760	COG2508	Transcriptional regulator
EI981_RS00765	COG3842	ATPase activity
EI981_RS00775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EI981_RS00780	COG0546	phosphoglycolate phosphatase activity
EI981_RS00785	COG0110	maltose O-acetyltransferase activity
EI981_RS00795	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EI981_RS00800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EI981_RS00805	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EI981_RS00810	COG0131	Imidazoleglycerol-phosphate dehydratase
EI981_RS00815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EI981_RS00820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EI981_RS00825	COG0107	imidazoleglycerol-phosphate synthase activity
EI981_RS00830	COG0140	phosphoribosyl-ATP diphosphatase activity
EI981_RS00830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EI981_RS00835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EI981_RS00855	COG2197	response regulator
EI981_RS00860	COG4585	Histidine kinase
EI981_RS00865	COG0842	Transport permease protein
EI981_RS00870	COG1131	(ABC) transporter
EI981_RS00885	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS00910	COG2205	protein histidine kinase activity
EI981_RS00915	COG0745	RESPONSE REGULATOR receiver
EI981_RS00930	COG1940	carbohydrate kinase activity
EI981_RS00935	COG1660	Displays ATPase and GTPase activities
EI981_RS00940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EI981_RS00945	COG1481	regulation of sporulation
EI981_RS00950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI981_RS00965	COG1176	ABC-type spermidine putrescine transport system, permease component I
EI981_RS00970	COG1177	transmembrane transport
EI981_RS00975	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EI981_RS00980	COG2311	Membrane
EI981_RS00985	COG0745	RESPONSE REGULATOR receiver
EI981_RS00990	COG2205	protein histidine kinase activity
EI981_RS01005	COG0740	serine-type endopeptidase activity
EI981_RS01020	COG1609	Transcriptional regulator
EI981_RS01025	COG4209	transmembrane transport
EI981_RS01030	COG0395	ABC-type sugar transport system, permease component
EI981_RS01055	COG0126	phosphoglycerate kinase activity
EI981_RS01060	COG0149	triose-phosphate isomerase activity
EI981_RS01065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EI981_RS01070	COG0148	phosphopyruvate hydratase activity
EI981_RS01075	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EI981_RS01080	COG0557	exoribonuclease II activity
EI981_RS01085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EI981_RS01115	COG1368	sulfuric ester hydrolase activity
EI981_RS01120	COG0840	transmembrane signaling receptor activity
EI981_RS01135	COG2972	Histidine kinase
EI981_RS01160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI981_RS01180	COG0604	alcohol dehydrogenase
EI981_RS01190	COG1368	sulfuric ester hydrolase activity
EI981_RS01195	COG1368	sulfuric ester hydrolase activity
EI981_RS01220	COG3693	PFAM glycoside hydrolase, family 10
EI981_RS01230	COG0328	RNA-DNA hybrid ribonuclease activity
EI981_RS01230	COG3341	Caulimovirus viroplasmin
EI981_RS01235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EI981_RS01260	COG1335	isochorismatase
EI981_RS01275	COG2111	Na H antiporter
EI981_RS01275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EI981_RS01280	COG2111	Na H antiporter
EI981_RS01285	COG1006	Multisubunit Na H antiporter MnhC subunit
EI981_RS01290	COG0651	ATP synthesis coupled electron transport
EI981_RS01295	COG1863	multisubunit Na H antiporter MnhE subunit
EI981_RS01300	COG2212	antiporter activity
EI981_RS01305	COG1320	monovalent cation:proton antiporter activity
EI981_RS01310	COG0488	(ABC) transporter
EI981_RS01325	COG3118	belongs to the thioredoxin family
EI981_RS01330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EI981_RS01335	COG1937	Protein conserved in bacteria
EI981_RS01340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EI981_RS01345	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI981_RS01350	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EI981_RS01355	COG1757	Na H antiporter
EI981_RS01375	COG2312	Erythromycin esterase
EI981_RS01380	COG0745	RESPONSE REGULATOR receiver
EI981_RS01395	COG1349	DNA-binding transcription factor activity
EI981_RS01405	COG1178	ABC-type Fe3 transport system permease component
EI981_RS01425	COG0662	Cupin 2, conserved barrel domain protein
EI981_RS01440	COG3693	PFAM glycoside hydrolase, family 10
EI981_RS01445	COG0450	alkyl hydroperoxide reductase
EI981_RS01455	COG1609	Transcriptional regulator
EI981_RS01460	COG1653	transport
EI981_RS01465	COG1175	transmembrane transport
EI981_RS01470	COG0395	ABC-type sugar transport system, permease component
EI981_RS01475	COG1486	melibiose metabolic process
EI981_RS01480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EI981_RS01485	COG3420	alginic acid biosynthetic process
EI981_RS01490	COG1657	PFAM Prenyltransferase squalene oxidase
EI981_RS01500	COG1533	DNA photolyase activity
EI981_RS01510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EI981_RS01515	COG2378	regulation of single-species biofilm formation
EI981_RS01525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EI981_RS01530	COG3654	unkown
EI981_RS01645	COG2081	HI0933 family
EI981_RS01650	COG2081	HI0933 family
EI981_RS01705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EI981_RS01725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EI981_RS01730	COG1011	Hydrolase
EI981_RS01735	COG0300	oxidoreductase activity
EI981_RS01750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI981_RS01755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EI981_RS01760	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS01770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI981_RS01775	COG1136	(ABC) transporter
EI981_RS01780	COG0577	efflux transmembrane transporter activity
EI981_RS01785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI981_RS01795	COG2608	mercury ion transmembrane transporter activity
EI981_RS01815	COG4977	sequence-specific DNA binding
EI981_RS01815	COG1917	Cupin 2, conserved barrel domain protein
EI981_RS01820	COG1609	Transcriptional regulator
EI981_RS01830	COG0235	Class ii aldolase
EI981_RS01835	COG2160	L-arabinose isomerase activity
EI981_RS01845	COG1842	Phage shock protein A
EI981_RS01850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EI981_RS01855	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EI981_RS01860	COG4260	virion core protein, lumpy skin disease virus
EI981_RS01865	COG0596	Alpha beta hydrolase
EI981_RS01890	COG4209	transmembrane transport
EI981_RS01895	COG0395	ABC-type sugar transport system, permease component
EI981_RS01910	COG0673	inositol 2-dehydrogenase activity
EI981_RS01915	COG1917	Cupin 2, conserved barrel domain protein
EI981_RS01915	COG4977	sequence-specific DNA binding
EI981_RS01930	COG2972	Histidine kinase
EI981_RS01935	COG2207	Transcriptional regulator
EI981_RS01935	COG1917	Cupin 2, conserved barrel domain protein
EI981_RS01965	COG1914	H( )-stimulated, divalent metal cation uptake system
EI981_RS01980	COG0673	inositol 2-dehydrogenase activity
EI981_RS01985	COG0583	DNA-binding transcription factor activity
EI981_RS01995	COG1115	amino acid carrier protein
EI981_RS02005	COG3279	Response regulator of the LytR AlgR family
EI981_RS02010	COG1131	(ABC) transporter
EI981_RS02040	COG1653	transport
EI981_RS02045	COG0395	ABC-type sugar transport system, permease component
EI981_RS02050	COG4209	transmembrane transport
EI981_RS02055	COG2207	Transcriptional regulator
EI981_RS02070	COG2217	Heavy metal translocating P-type atpase
EI981_RS02105	COG4585	Histidine kinase
EI981_RS02110	COG2197	response regulator
EI981_RS02115	COG1278	Cold shock
EI981_RS02125	COG2746	aminoglycoside 3-N-acetyltransferase activity
EI981_RS02130	COG0314	molybdopterin synthase activity
EI981_RS02135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EI981_RS02140	COG1733	regulation of RNA biosynthetic process
EI981_RS02150	COG3275	phosphorelay sensor kinase activity
EI981_RS02155	COG4753	response regulator
EI981_RS02155	COG2207	Transcriptional regulator
EI981_RS02155	COG4753	response regulator
EI981_RS02155	COG2207	Transcriptional regulator
EI981_RS02160	COG2814	Major facilitator Superfamily
EI981_RS02190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EI981_RS02210	COG0697	spore germination
EI981_RS02215	COG0549	Belongs to the carbamate kinase family
EI981_RS02225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EI981_RS02230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EI981_RS02235	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EI981_RS02240	COG3257	ureidoglycine aminohydrolase activity
EI981_RS02245	COG2814	Major facilitator Superfamily
EI981_RS02250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EI981_RS02260	COG0657	acetylesterase activity
EI981_RS02275	COG4209	transmembrane transport
EI981_RS02280	COG0395	ABC-type sugar transport system, permease component
EI981_RS02285	COG1653	transport
EI981_RS02295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI981_RS02310	COG2188	Transcriptional regulator
EI981_RS02320	COG0561	phosphatase activity
EI981_RS02340	COG1012	belongs to the aldehyde dehydrogenase family
EI981_RS02345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EI981_RS02360	COG0697	spore germination
EI981_RS02370	COG2222	sugar isomerase
EI981_RS02375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EI981_RS02380	COG1940	carbohydrate kinase activity
EI981_RS02390	COG1105	Belongs to the carbohydrate kinase PfkB family
EI981_RS02395	COG1349	DNA-binding transcription factor activity
EI981_RS02400	COG0667	Aldo Keto reductase
EI981_RS02415	COG0366	Alpha amylase catalytic
EI981_RS02430	COG1368	sulfuric ester hydrolase activity
EI981_RS02450	COG3394	polysaccharide catabolic process
EI981_RS02465	COG1595	DNA-templated transcription, initiation
EI981_RS02480	COG2207	Transcriptional regulator
EI981_RS02480	COG4753	response regulator
EI981_RS02485	COG3275	phosphorelay sensor kinase activity
EI981_RS02495	COG0395	ABC-type sugar transport system, permease component
EI981_RS02500	COG4209	transmembrane transport
EI981_RS02510	COG2116	formate transmembrane transporter activity
EI981_RS02515	COG1442	glycosyl transferase family 8
EI981_RS02525	COG0425	Belongs to the sulfur carrier protein TusA family
EI981_RS02535	COG2115	Belongs to the xylose isomerase family
EI981_RS02540	COG1070	Carbohydrate kinase
EI981_RS02545	COG2972	Histidine kinase
EI981_RS02550	COG4753	response regulator
EI981_RS02550	COG2207	Transcriptional regulator
EI981_RS02555	COG1653	transport
EI981_RS02560	COG4209	transmembrane transport
EI981_RS02585	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EI981_RS02595	COG0745	RESPONSE REGULATOR receiver
EI981_RS02600	COG5002	protein histidine kinase activity
EI981_RS02620	COG0673	inositol 2-dehydrogenase activity
EI981_RS02630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI981_RS02640	COG0714	Associated with various cellular activities
EI981_RS02665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI981_RS02680	COG1253	flavin adenine dinucleotide binding
EI981_RS02685	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EI981_RS02700	COG1523	belongs to the glycosyl hydrolase 13 family
EI981_RS02710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI981_RS02715	COG1609	Transcriptional regulator
EI981_RS02735	COG1653	transport
EI981_RS02740	COG4209	transmembrane transport
EI981_RS02745	COG0395	ABC-type sugar transport system, permease component
EI981_RS02750	COG2972	Histidine kinase
EI981_RS02755	COG2207	Transcriptional regulator
EI981_RS02755	COG4753	response regulator
EI981_RS02765	COG3275	phosphorelay sensor kinase activity
EI981_RS02770	COG2201	protein-glutamate methylesterase activity
EI981_RS02775	COG4209	transmembrane transport
EI981_RS02780	COG0395	ABC-type sugar transport system, permease component
EI981_RS02785	COG1653	transport
EI981_RS02815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EI981_RS02825	COG1459	type II secretion system
EI981_RS02865	COG4555	ABC transporter
EI981_RS02875	COG1842	Phage shock protein A
EI981_RS02885	COG0584	glycerophosphoryl diester phosphodiesterase
EI981_RS02895	COG4549	nuclear export factor GLE1
EI981_RS02900	COG2372	response to copper ion
EI981_RS02900	COG1276	copper resistance
EI981_RS02915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS02925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EI981_RS02930	COG1845	cytochrome c oxidase, subunit III
EI981_RS02940	COG1937	Protein conserved in bacteria
EI981_RS02945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EI981_RS02970	COG0778	Nitroreductase
EI981_RS02995	COG4585	Histidine kinase
EI981_RS03000	COG2197	response regulator
EI981_RS03005	COG0084	hydrolase, TatD family'
EI981_RS03015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EI981_RS03015	COG2199	diguanylate cyclase activity
EI981_RS03025	COG1116	anion transmembrane transporter activity
EI981_RS03030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EI981_RS03040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EI981_RS03045	COG4846	Membrane protein involved in cytochrome C biogenesis
EI981_RS03055	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EI981_RS03065	COG4208	sulfate ABC transporter
EI981_RS03070	COG5583	Uncharacterized small protein (DUF2292)
EI981_RS03080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EI981_RS03080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EI981_RS03085	COG0431	NADPH-dependent FMN reductase
EI981_RS03140	COG3279	Response regulator of the LytR AlgR family
EI981_RS03145	COG2972	Histidine kinase
EI981_RS03150	COG1653	transport
EI981_RS03155	COG1175	transmembrane transport
EI981_RS03160	COG0395	ABC-type sugar transport system, permease component
EI981_RS03170	COG1132	(ABC) transporter
EI981_RS03175	COG1132	(ABC) transporter
EI981_RS03180	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EI981_RS03185	COG0583	DNA-binding transcription factor activity
EI981_RS03210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EI981_RS03215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EI981_RS03220	COG0602	queuosine metabolic process
EI981_RS03230	COG0011	TIGRFAM Protein of
EI981_RS03270	COG1122	ATPase activity
EI981_RS03275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EI981_RS03280	COG0826	peptidase U32
EI981_RS03290	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EI981_RS03295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EI981_RS03300	COG4715	Zinc finger, swim domain protein
EI981_RS03315	COG1252	NADH dehydrogenase
EI981_RS03325	COG3263	regulation of cellular component size
EI981_RS03330	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EI981_RS03340	COG0251	oxidation-reduction process
EI981_RS03345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EI981_RS03355	COG2357	RelA SpoT domain protein
EI981_RS03370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EI981_RS03385	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EI981_RS03400	COG2010	Cytochrome c
EI981_RS03400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EI981_RS03415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EI981_RS03420	COG3336	cytochrome c oxidase
EI981_RS03430	COG2329	Antibiotic biosynthesis monooxygenase
EI981_RS03445	COG1131	(ABC) transporter
EI981_RS03450	COG4152	abc transporter atp-binding protein
EI981_RS03455	COG1668	transmembrane transport
EI981_RS03485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EI981_RS03490	COG5434	Belongs to the glycosyl hydrolase 28 family
EI981_RS03490	COG4632	Exopolysaccharide biosynthesis protein
EI981_RS03495	COG1307	EDD domain protein, DegV family
EI981_RS03505	COG0534	Mate efflux family protein
EI981_RS03510	COG1349	DNA-binding transcription factor activity
EI981_RS03515	COG1105	Belongs to the carbohydrate kinase PfkB family
EI981_RS03520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EI981_RS03520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EI981_RS03520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI981_RS03525	COG0622	Phosphoesterase
EI981_RS03530	COG1349	DNA-binding transcription factor activity
EI981_RS03540	COG1368	sulfuric ester hydrolase activity
EI981_RS03545	COG1956	GAF domain-containing protein
EI981_RS03550	COG1073	alpha beta
EI981_RS03570	COG4721	ABC-type cobalt transport system, permease component
EI981_RS03575	COG1122	ATPase activity
EI981_RS03580	COG0477	Major facilitator Superfamily
EI981_RS03590	COG1846	Transcriptional regulator
EI981_RS03605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EI981_RS03610	COG1757	Na H antiporter
EI981_RS03615	COG0251	oxidation-reduction process
EI981_RS03620	COG1131	(ABC) transporter
EI981_RS03630	COG2081	HI0933 family
EI981_RS03635	COG5002	protein histidine kinase activity
EI981_RS03645	COG2207	Transcriptional regulator
EI981_RS03645	COG3708	Transcriptional regulator
EI981_RS03655	COG1194	a g-specific adenine glycosylase
EI981_RS03670	COG0328	RNA-DNA hybrid ribonuclease activity
EI981_RS03675	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EI981_RS03680	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EI981_RS03690	COG0302	gtp cyclohydrolase
EI981_RS03695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EI981_RS03710	COG1073	alpha beta
EI981_RS03720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS03725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EI981_RS03735	COG1181	Belongs to the D-alanine--D-alanine ligase family
EI981_RS03745	COG0483	inositol monophosphate 1-phosphatase activity
EI981_RS03755	COG2226	methyltransferase
EI981_RS03765	COG1554	hydrolase, family 65, central catalytic
EI981_RS03770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI981_RS03775	COG2972	Histidine kinase
EI981_RS03785	COG1175	transmembrane transport
EI981_RS03800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EI981_RS03805	COG1316	TRANSCRIPTIONal
EI981_RS03810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EI981_RS03820	COG0583	DNA-binding transcription factor activity
EI981_RS03830	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
EI981_RS03835	COG0714	Associated with various cellular activities
EI981_RS03845	COG1305	Transglutaminase-like
EI981_RS03860	COG2252	PERMEase
EI981_RS03865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EI981_RS03870	COG4895	conserved protein (DUF2196)
EI981_RS03920	COG1737	Transcriptional regulator
EI981_RS03930	COG1175	transmembrane transport
EI981_RS03935	COG0395	ABC-type sugar transport system, permease component
EI981_RS03960	COG2972	Histidine kinase
EI981_RS03965	COG1653	transport
EI981_RS03970	COG2207	Transcriptional regulator
EI981_RS03970	COG4753	response regulator
EI981_RS03975	COG2261	transglycosylase associated protein
EI981_RS04000	COG2329	Antibiotic biosynthesis monooxygenase
EI981_RS04005	COG0708	Exodeoxyribonuclease III
EI981_RS04015	COG0583	DNA-binding transcription factor activity
EI981_RS04020	COG2814	Major facilitator Superfamily
EI981_RS04030	COG5564	TIM-barrel signal transduction protein
EI981_RS04040	COG5564	TIM-barrel signal transduction protein
EI981_RS04050	COG0463	Glycosyl transferase, family 2
EI981_RS04070	COG1215	transferase activity, transferring glycosyl groups
EI981_RS04085	COG2246	polysaccharide biosynthetic process
EI981_RS04095	COG5002	protein histidine kinase activity
EI981_RS04130	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EI981_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS04170	COG0730	response to heat
EI981_RS04195	COG3326	Membrane
EI981_RS04200	COG0589	response to stress
EI981_RS04210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EI981_RS04215	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EI981_RS04220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EI981_RS04225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EI981_RS04230	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EI981_RS04235	COG0047	phosphoribosylformylglycinamidine synthase activity
EI981_RS04240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EI981_RS04245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EI981_RS04250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EI981_RS04255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EI981_RS04280	COG0346	lactoylglutathione lyase activity
EI981_RS04285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EI981_RS04290	COG3507	Belongs to the glycosyl hydrolase 43 family
EI981_RS04295	COG1063	alcohol dehydrogenase
EI981_RS04305	COG1131	(ABC) transporter
EI981_RS04310	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EI981_RS04315	COG1725	Transcriptional regulator
EI981_RS04320	COG1131	(ABC) transporter
EI981_RS04330	COG2824	Alkylphosphonate utilization operon protein PhnA
EI981_RS04340	COG1131	(ABC) transporter
EI981_RS04350	COG1309	transcriptional regulator
EI981_RS04365	COG3384	dioxygenase
EI981_RS04370	COG1470	cell adhesion involved in biofilm formation
EI981_RS04375	COG1392	Phosphate transport regulator
EI981_RS04380	COG0306	phosphate transporter
EI981_RS04385	COG0598	Magnesium transport protein CorA
EI981_RS04390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EI981_RS04395	COG1442	glycosyl transferase family 8
EI981_RS04395	COG1216	Glycosyl transferase, family 2
EI981_RS04405	COG4496	protein, YerC YecD
EI981_RS04415	COG1597	lipid kinase activity
EI981_RS04420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EI981_RS04440	COG4916	TIR domain
EI981_RS04445	COG0653	protein targeting
EI981_RS04455	COG4209	transmembrane transport
EI981_RS04460	COG0395	ABC-type sugar transport system, permease component
EI981_RS04465	COG1653	transport
EI981_RS04475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EI981_RS04480	COG0544	peptidyl-prolyl cis-trans isomerase activity
EI981_RS04495	COG0366	Alpha amylase catalytic
EI981_RS04500	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EI981_RS04510	COG2814	Major facilitator Superfamily
EI981_RS04515	COG0640	Transcriptional regulator
EI981_RS04530	COG4509	Sortase family
EI981_RS04535	COG1131	(ABC) transporter
EI981_RS04695	COG1230	cation diffusion facilitator family transporter
EI981_RS04700	COG0640	Transcriptional regulator
EI981_RS04780	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
EI981_RS04785	COG0747	negative chemotaxis
EI981_RS04795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI981_RS04800	COG4172	Belongs to the ABC transporter superfamily
EI981_RS04805	COG4608	Belongs to the ABC transporter superfamily
EI981_RS04815	COG1228	amidohydrolase
EI981_RS04820	COG5504	Zn-dependent protease
EI981_RS04840	COG4209	transmembrane transport
EI981_RS04845	COG0395	ABC-type sugar transport system, permease component
EI981_RS04860	COG2207	Transcriptional regulator
EI981_RS04860	COG4753	response regulator
EI981_RS04875	COG1609	Transcriptional regulator
EI981_RS04885	COG3069	C4-dicarboxylate transmembrane transporter activity
EI981_RS04895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EI981_RS04900	COG2186	Transcriptional regulator
EI981_RS04905	COG0277	FAD linked oxidase domain protein
EI981_RS04910	COG0247	lactate metabolic process
EI981_RS04920	COG0402	S-adenosylhomocysteine deaminase activity
EI981_RS04930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EI981_RS04940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EI981_RS04945	COG2011	ABC-type metal ion transport system permease component
EI981_RS04950	COG1854	S-ribosylhomocysteine lyase activity
EI981_RS04955	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS04965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EI981_RS04975	COG2357	RelA SpoT domain protein
EI981_RS04990	COG1396	sequence-specific DNA binding
EI981_RS05000	COG1595	DNA-templated transcription, initiation
EI981_RS05015	COG1609	Transcriptional regulator
EI981_RS05060	COG2390	Transcriptional regulator
EI981_RS05065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EI981_RS05075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EI981_RS05080	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EI981_RS05090	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EI981_RS05095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EI981_RS05105	COG0534	Mate efflux family protein
EI981_RS05140	COG3541	Predicted nucleotidyltransferase
EI981_RS05155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EI981_RS05170	COG1404	Belongs to the peptidase S8 family
EI981_RS05175	COG0402	S-adenosylhomocysteine deaminase activity
EI981_RS05180	COG0402	S-adenosylhomocysteine deaminase activity
EI981_RS05185	COG0583	DNA-binding transcription factor activity
EI981_RS05195	COG3706	GGDEF domain
EI981_RS05205	COG1312	Catalyzes the dehydration of D-mannonate
EI981_RS05220	COG1175	transmembrane transport
EI981_RS05225	COG0395	ABC-type sugar transport system, permease component
EI981_RS05230	COG2972	Histidine kinase
EI981_RS05235	COG4753	response regulator
EI981_RS05235	COG2207	Transcriptional regulator
EI981_RS05235	COG4753	response regulator
EI981_RS05235	COG2207	Transcriptional regulator
EI981_RS05250	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EI981_RS05255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EI981_RS05260	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EI981_RS05265	COG0351	phosphomethylpyrimidine kinase
EI981_RS05270	COG0352	thiamine-phosphate diphosphorylase activity
EI981_RS05280	COG0745	RESPONSE REGULATOR receiver
EI981_RS05290	COG0577	efflux transmembrane transporter activity
EI981_RS05295	COG1136	(ABC) transporter
EI981_RS05320	COG0673	inositol 2-dehydrogenase activity
EI981_RS05325	COG1595	DNA-templated transcription, initiation
EI981_RS05350	COG1175	transmembrane transport
EI981_RS05355	COG0395	ABC-type sugar transport system, permease component
EI981_RS05360	COG1554	hydrolase, family 65, central catalytic
EI981_RS05370	COG2972	Histidine kinase
EI981_RS05375	COG2201	protein-glutamate methylesterase activity
EI981_RS05385	COG3693	PFAM glycoside hydrolase, family 10
EI981_RS05395	COG4474	Belongs to the UPF0398 family
EI981_RS05410	COG0653	protein targeting
EI981_RS05425	COG0840	transmembrane signaling receptor activity
EI981_RS05455	COG1193	negative regulation of DNA recombination
EI981_RS05490	COG0584	glycerophosphoryl diester phosphodiesterase
EI981_RS05495	COG0561	phosphatase activity
EI981_RS05515	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EI981_RS05525	COG1380	Effector of murein hydrolase LrgA
EI981_RS05530	COG1346	cytolysis
EI981_RS05555	COG0445	tRNA wobble uridine modification
EI981_RS05650	COG2258	MOSC domain
EI981_RS05750	COG1619	proteins homologs of microcin C7 resistance protein MccF
EI981_RS05755	COG0251	oxidation-reduction process
EI981_RS05765	COG1361	Conserved repeat domain
EI981_RS05775	COG0583	DNA-binding transcription factor activity
EI981_RS05785	COG1132	(ABC) transporter
EI981_RS05800	COG1653	transport
EI981_RS05805	COG1175	transmembrane transport
EI981_RS05810	COG0395	ABC-type sugar transport system, permease component
EI981_RS05820	COG1309	transcriptional regulator
EI981_RS05845	COG1131	(ABC) transporter
EI981_RS05860	COG2207	Transcriptional regulator
EI981_RS05940	COG1674	ftsk spoiiie
EI981_RS05985	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EI981_RS06010	COG5522	Integral membrane protein (intg_mem_TP0381)
EI981_RS06020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EI981_RS06025	COG0765	amino acid transport
EI981_RS06040	COG1193	negative regulation of DNA recombination
EI981_RS06055	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EI981_RS06060	COG1704	LemA family
EI981_RS06070	COG3610	response to peptide
EI981_RS06075	COG2966	Psort location CytoplasmicMembrane, score
EI981_RS06080	COG1376	ErfK ybiS ycfS ynhG family protein
EI981_RS06095	COG1609	Transcriptional regulator
EI981_RS06110	COG2205	protein histidine kinase activity
EI981_RS06130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EI981_RS06140	COG0783	Belongs to the Dps family
EI981_RS06145	COG0840	transmembrane signaling receptor activity
EI981_RS06155	COG1309	transcriptional regulator
EI981_RS06160	COG1511	domain protein
EI981_RS06165	COG0070	glutamate synthase
EI981_RS06165	COG0067	glutamate synthase
EI981_RS06165	COG0069	glutamate synthase activity
EI981_RS06170	COG1131	(ABC) transporter
EI981_RS06175	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EI981_RS06185	COG0739	heme binding
EI981_RS06200	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EI981_RS06205	COG0802	atpase or kinase
EI981_RS06210	COG1214	PFAM Peptidase M22, glycoprotease
EI981_RS06215	COG0456	acetyltransferase
EI981_RS06235	COG0739	heme binding
EI981_RS06240	COG2746	aminoglycoside 3-N-acetyltransferase activity
EI981_RS06245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EI981_RS06255	COG0488	(ABC) transporter
EI981_RS06260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EI981_RS06265	COG0315	cyclic pyranopterin monophosphate synthase activity
EI981_RS06270	COG0521	Mo-molybdopterin cofactor biosynthetic process
EI981_RS06275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EI981_RS06280	COG0805	protein transport
EI981_RS06285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EI981_RS06290	COG0459	protein refolding
EI981_RS06330	COG0667	Aldo Keto reductase
EI981_RS06360	COG2814	Major facilitator Superfamily
EI981_RS06365	COG4209	transmembrane transport
EI981_RS06370	COG0395	ABC-type sugar transport system, permease component
EI981_RS06380	COG2972	Histidine kinase
EI981_RS06385	COG4753	response regulator
EI981_RS06385	COG2207	Transcriptional regulator
EI981_RS06390	COG1653	transport
EI981_RS06395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EI981_RS06400	COG2207	Transcriptional regulator
EI981_RS06415	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS06420	COG4753	response regulator
EI981_RS06420	COG2207	Transcriptional regulator
EI981_RS06425	COG3275	phosphorelay sensor kinase activity
EI981_RS06430	COG1175	transmembrane transport
EI981_RS06435	COG0395	ABC-type sugar transport system, permease component
EI981_RS06460	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EI981_RS06475	COG4209	transmembrane transport
EI981_RS06480	COG0395	ABC-type sugar transport system, permease component
EI981_RS06510	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EI981_RS06515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EI981_RS06520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EI981_RS06525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EI981_RS06530	COG0531	amino acid
EI981_RS06545	COG1609	Transcriptional regulator
EI981_RS06550	COG4209	transmembrane transport
EI981_RS06555	COG0395	ABC-type sugar transport system, permease component
EI981_RS06565	COG1621	beta-fructofuranosidase activity
EI981_RS06570	COG1621	beta-fructofuranosidase activity
EI981_RS06590	COG3321	synthase
EI981_RS06590	COG4221	oxidoreductase activity
EI981_RS06590	COG0300	oxidoreductase activity
EI981_RS06590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS06590	COG4221	oxidoreductase activity
EI981_RS06590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS06590	COG3321	synthase
EI981_RS06590	COG0300	oxidoreductase activity
EI981_RS06595	COG4221	oxidoreductase activity
EI981_RS06595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS06595	COG0300	oxidoreductase activity
EI981_RS06595	COG3321	synthase
EI981_RS06600	COG4221	oxidoreductase activity
EI981_RS06600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS06600	COG3321	synthase
EI981_RS06600	COG0300	oxidoreductase activity
EI981_RS06605	COG3321	synthase
EI981_RS06605	COG4221	oxidoreductase activity
EI981_RS06605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS06605	COG0300	oxidoreductase activity
EI981_RS06610	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS06610	COG3321	synthase
EI981_RS06610	COG4221	oxidoreductase activity
EI981_RS06610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EI981_RS06615	COG0300	oxidoreductase activity
EI981_RS06615	COG3321	synthase
EI981_RS06615	COG4221	oxidoreductase activity
EI981_RS06615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS06615	COG0300	oxidoreductase activity
EI981_RS06615	COG3321	synthase
EI981_RS06615	COG4221	oxidoreductase activity
EI981_RS06615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS06620	COG0300	oxidoreductase activity
EI981_RS06620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS06620	COG3321	synthase
EI981_RS06620	COG4221	oxidoreductase activity
EI981_RS06625	COG3321	synthase
EI981_RS06625	COG4221	oxidoreductase activity
EI981_RS06625	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS06625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EI981_RS06640	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EI981_RS06640	COG2070	2-Nitropropane dioxygenase
EI981_RS06645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS06650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EI981_RS06655	COG3425	synthase
EI981_RS06660	COG1024	Enoyl-CoA hydratase
EI981_RS06675	COG2086	electron transfer activity
EI981_RS06680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EI981_RS06690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI981_RS06700	COG0318	PFAM AMP-dependent synthetase and ligase
EI981_RS06705	COG1960	acyl-CoA dehydrogenase activity
EI981_RS06710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EI981_RS06725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EI981_RS06735	COG0745	RESPONSE REGULATOR receiver
EI981_RS06740	COG5002	protein histidine kinase activity
EI981_RS06745	COG1136	(ABC) transporter
EI981_RS06765	COG2217	Heavy metal translocating P-type atpase
EI981_RS06770	COG2217	Heavy metal translocating P-type atpase
EI981_RS06785	COG0673	inositol 2-dehydrogenase activity
EI981_RS06805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EI981_RS06810	COG2169	Transcriptional regulator
EI981_RS06815	COG2140	Oxalate decarboxylase
EI981_RS06825	COG4209	transmembrane transport
EI981_RS06830	COG0395	ABC-type sugar transport system, permease component
EI981_RS06835	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EI981_RS06850	COG4989	oxidoreductase activity
EI981_RS06855	COG0789	Transcriptional regulator
EI981_RS06865	COG1904	glucuronate isomerase
EI981_RS06870	COG2721	sulfolactate sulfo-lyase activity
EI981_RS06875	COG0246	Mannitol dehydrogenase
EI981_RS06880	COG1609	Transcriptional regulator
EI981_RS06890	COG2856	Zn peptidase
EI981_RS06980	COG3628	GPW Gp25 family protein
EI981_RS06985	COG3299	homolog of phage Mu protein gp47
EI981_RS07045	COG1652	LysM domain
EI981_RS07045	COG2823	Periplasmic or secreted lipoprotein
EI981_RS07065	COG3299	homolog of phage Mu protein gp47
EI981_RS07110	COG3964	amidohydrolase
EI981_RS07130	COG2188	Transcriptional regulator
EI981_RS07135	COG1309	transcriptional regulator
EI981_RS07150	COG1917	Cupin 2, conserved barrel domain protein
EI981_RS07150	COG2207	Transcriptional regulator
EI981_RS07155	COG2720	vancomycin resistance protein
EI981_RS07160	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
EI981_RS07170	COG1070	Carbohydrate kinase
EI981_RS07185	COG0667	Aldo Keto reductase
EI981_RS07190	COG1609	Transcriptional regulator
EI981_RS07200	COG0395	ABC-type sugar transport system, permease component
EI981_RS07205	COG1175	transmembrane transport
EI981_RS07210	COG2610	gluconate transmembrane transporter activity
EI981_RS07215	COG1929	Belongs to the glycerate kinase type-1 family
EI981_RS07220	COG3835	regulator
EI981_RS07225	COG0745	RESPONSE REGULATOR receiver
EI981_RS07230	COG3850	Histidine kinase
EI981_RS07230	COG5002	protein histidine kinase activity
EI981_RS07240	COG1840	ABC-type Fe3 transport system, periplasmic component
EI981_RS07260	COG2207	Transcriptional regulator
EI981_RS07260	COG4753	response regulator
EI981_RS07260	COG4753	response regulator
EI981_RS07260	COG2207	Transcriptional regulator
EI981_RS07265	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS07275	COG1501	Belongs to the glycosyl hydrolase 31 family
EI981_RS07280	COG2972	Histidine kinase
EI981_RS07285	COG4209	transmembrane transport
EI981_RS07290	COG0395	ABC-type sugar transport system, permease component
EI981_RS07320	COG3266	domain, Protein
EI981_RS07320	COG2911	Protein conserved in bacteria
EI981_RS07320	COG1361	Conserved repeat domain
EI981_RS07330	COG3344	reverse transcriptase
EI981_RS07350	COG3711	transcriptional antiterminator
EI981_RS07355	COG2190	(PTS) system
EI981_RS07355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EI981_RS07355	COG1263	PTS System
EI981_RS07360	COG2723	6-phospho-beta-galactosidase activity
EI981_RS07365	COG3590	peptidase
EI981_RS07395	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EI981_RS07400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EI981_RS07405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI981_RS07410	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EI981_RS07410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EI981_RS07435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EI981_RS07440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EI981_RS07450	COG2801	Transposase and inactivated derivatives
EI981_RS07465	COG3279	Response regulator of the LytR AlgR family
EI981_RS07470	COG1361	Conserved repeat domain
EI981_RS07470	COG3266	domain, Protein
EI981_RS07470	COG2911	Protein conserved in bacteria
EI981_RS07475	COG2972	Histidine kinase
EI981_RS07475	COG0745	RESPONSE REGULATOR receiver
EI981_RS07485	COG1653	transport
EI981_RS07495	COG1175	transmembrane transport
EI981_RS07500	COG0395	ABC-type sugar transport system, permease component
EI981_RS07515	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS07525	COG3693	PFAM glycoside hydrolase, family 10
EI981_RS07615	COG4821	SIS domain
EI981_RS07630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI981_RS07640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI981_RS07660	COG1363	Peptidase, m42
EI981_RS07670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI981_RS07690	COG0714	Associated with various cellular activities
EI981_RS07700	COG1305	Transglutaminase-like
EI981_RS07705	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EI981_RS07710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EI981_RS07715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EI981_RS07720	COG1534	Rna-binding protein
EI981_RS07725	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EI981_RS07730	COG1713	HD superfamily hydrolase involved in NAD metabolism
EI981_RS07735	COG0799	negative regulation of ribosome biogenesis
EI981_RS07740	COG2996	Protein conserved in bacteria
EI981_RS07745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EI981_RS07750	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS07770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EI981_RS07770	COG2755	lipolytic protein G-D-S-L family
EI981_RS07805	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EI981_RS07810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EI981_RS07815	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EI981_RS07820	COG3842	ATPase activity
EI981_RS07830	COG1176	ABC-type spermidine putrescine transport system, permease component I
EI981_RS07845	COG4209	transmembrane transport
EI981_RS07850	COG0395	ABC-type sugar transport system, permease component
EI981_RS07855	COG1653	transport
EI981_RS07865	COG0494	nUDIX hydrolase
EI981_RS07870	COG1335	isochorismatase
EI981_RS07875	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EI981_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS07910	COG1349	DNA-binding transcription factor activity
EI981_RS07915	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EI981_RS07920	COG3534	alpha-L-arabinofuranosidase
EI981_RS07935	COG0800	Aldolase
EI981_RS07940	COG0673	inositol 2-dehydrogenase activity
EI981_RS07950	COG0673	inositol 2-dehydrogenase activity
EI981_RS07955	COG2972	Histidine kinase
EI981_RS07960	COG2207	Transcriptional regulator
EI981_RS07965	COG2182	Extracellular solute-binding protein
EI981_RS07970	COG1175	transmembrane transport
EI981_RS07980	COG1554	hydrolase, family 65, central catalytic
EI981_RS07985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI981_RS08065	COG2814	Major facilitator Superfamily
EI981_RS08085	COG0495	leucyl-tRNA aminoacylation
EI981_RS08090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EI981_RS08095	COG1596	polysaccharide export
EI981_RS08095	COG1555	photosystem II stabilization
EI981_RS08105	COG2333	competence protein COMEC
EI981_RS08105	COG0658	competence protein
EI981_RS08110	COG1595	DNA-templated transcription, initiation
EI981_RS08120	COG1466	dna polymerase III delta subunit
EI981_RS08125	COG0268	Binds directly to 16S ribosomal RNA
EI981_RS08145	COG1609	Transcriptional regulator
EI981_RS08150	COG2814	Major facilitator Superfamily
EI981_RS08155	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EI981_RS08165	COG0481	GTPase activity
EI981_RS08170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EI981_RS08175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EI981_RS08175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EI981_RS08180	COG1420	regulation of RNA biosynthetic process
EI981_RS08220	COG2264	protein methyltransferase activity
EI981_RS08225	COG1994	Peptidase M50
EI981_RS08230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EI981_RS08235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI981_RS08245	COG1283	sodium-dependent phosphate transmembrane transporter activity
EI981_RS08250	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EI981_RS08255	COG0697	spore germination
EI981_RS08260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS08265	COG1609	Transcriptional regulator
EI981_RS08270	COG1063	alcohol dehydrogenase
EI981_RS08280	COG1074	ATP-dependent DNA helicase activity
EI981_RS08285	COG0420	3'-5' exonuclease activity
EI981_RS08290	COG0419	ATPase involved in DNA repair
EI981_RS08295	COG2197	response regulator
EI981_RS08305	COG1131	(ABC) transporter
EI981_RS08320	COG0537	adenosine 5'-monophosphoramidase activity
EI981_RS08325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EI981_RS08330	COG1610	YqeY-like protein
EI981_RS08345	COG1702	phosphate starvation-inducible protein PhoH
EI981_RS08350	COG1480	7TM receptor with intracellular HD hydrolase
EI981_RS08355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EI981_RS08360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EI981_RS08365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EI981_RS08375	COG1381	Involved in DNA repair and RecF pathway recombination
EI981_RS08380	COG0752	glycyl-tRNA synthetase alpha subunit
EI981_RS08385	COG0751	glycine-tRNA ligase activity
EI981_RS08390	COG1671	Belongs to the UPF0178 family
EI981_RS08395	COG0358	DNA primase activity
EI981_RS08405	COG2384	SAM-dependent methyltransferase
EI981_RS08410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EI981_RS08435	COG0741	lytic transglycosylase activity
EI981_RS08440	COG1104	cysteine desulfurase activity
EI981_RS08445	COG0301	tRNA thio-modification
EI981_RS08450	COG0861	Integral membrane protein TerC family
EI981_RS08455	COG0861	Integral membrane protein TerC family
EI981_RS08465	COG1217	gtp-binding protein TYPA
EI981_RS08475	COG1316	TRANSCRIPTIONal
EI981_RS08490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EI981_RS08515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EI981_RS08525	COG4166	transmembrane transport
EI981_RS08530	COG0601	transmembrane transport
EI981_RS08535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI981_RS08540	COG0444	Belongs to the ABC transporter superfamily
EI981_RS08545	COG4608	Belongs to the ABC transporter superfamily
EI981_RS08555	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EI981_RS08560	COG2001	Belongs to the MraZ family
EI981_RS08565	COG0275	rRNA processing
EI981_RS08575	COG0768	penicillin binding
EI981_RS08580	COG0768	penicillin binding
EI981_RS08590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EI981_RS08595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EI981_RS08600	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EI981_RS08605	COG0772	Belongs to the SEDS family
EI981_RS08615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EI981_RS08620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EI981_RS08625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EI981_RS08630	COG0849	cell division
EI981_RS08635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EI981_RS08645	COG1191	sigma factor activity
EI981_RS08650	COG1191	sigma factor activity
EI981_RS08655	COG1873	PFAM PRC-barrel domain
EI981_RS08660	COG1496	oxidoreductase activity
EI981_RS08665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EI981_RS08670	COG1799	cell septum assembly
EI981_RS08675	COG0762	integral membrane protein
EI981_RS08680	COG2302	S4 RNA-binding domain
EI981_RS08685	COG3599	regulation of cell shape
EI981_RS08705	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EI981_RS08710	COG0564	pseudouridine synthase activity
EI981_RS08720	COG0436	Aminotransferase
EI981_RS08725	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EI981_RS08730	COG0540	Belongs to the ATCase OTCase family
EI981_RS08735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EI981_RS08745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EI981_RS08750	COG0284	orotidine-5'-phosphate decarboxylase activity
EI981_RS08760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI981_RS08765	COG1733	regulation of RNA biosynthetic process
EI981_RS08775	COG1136	(ABC) transporter
EI981_RS08790	COG0577	efflux transmembrane transporter activity
EI981_RS08790	COG1136	(ABC) transporter
EI981_RS08840	COG2333	competence protein COMEC
EI981_RS08840	COG0658	competence protein
EI981_RS08855	COG1482	cell wall glycoprotein biosynthetic process
EI981_RS08860	COG1940	carbohydrate kinase activity
EI981_RS08865	COG1609	Transcriptional regulator
EI981_RS08890	COG1054	Belongs to the UPF0176 family
EI981_RS08915	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EI981_RS08920	COG0488	(ABC) transporter
EI981_RS08935	COG0300	oxidoreductase activity
EI981_RS09045	COG1234	tRNA 3'-trailer cleavage
EI981_RS09055	COG3906	Belongs to the UPF0473 family
EI981_RS09060	COG1982	Orn Lys Arg decarboxylase major
EI981_RS09070	COG4493	Belongs to the UPF0637 family
EI981_RS09080	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EI981_RS09085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EI981_RS09090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EI981_RS09095	COG1832	CoA-binding protein
EI981_RS09100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EI981_RS09110	COG0693	protein deglycase activity
EI981_RS09125	COG1609	Transcriptional regulator
EI981_RS09130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EI981_RS09135	COG0123	including yeast histone deacetylase and acetoin utilization protein
EI981_RS09140	COG0454	-acetyltransferase
EI981_RS09145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EI981_RS09150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EI981_RS09155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EI981_RS09160	COG2199	diguanylate cyclase activity
EI981_RS09160	COG2203	Gaf domain
EI981_RS09170	COG2309	aminopeptidase activity
EI981_RS09180	COG4838	Belongs to the UPF0358 family
EI981_RS09185	COG0387	Pfam Sodium calcium exchanger
EI981_RS09190	COG1302	Protein conserved in bacteria
EI981_RS09195	COG0772	Belongs to the SEDS family
EI981_RS09205	COG1473	amidohydrolase
EI981_RS09215	COG0659	secondary active sulfate transmembrane transporter activity
EI981_RS09225	COG1053	succinate dehydrogenase
EI981_RS09255	COG0583	DNA-binding transcription factor activity
EI981_RS09260	COG0613	PHP domain protein
EI981_RS09265	COG0561	phosphatase activity
EI981_RS09275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EI981_RS09280	COG2378	regulation of single-species biofilm formation
EI981_RS09290	COG0583	DNA-binding transcription factor activity
EI981_RS09295	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EI981_RS09300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EI981_RS09305	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EI981_RS09310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EI981_RS09310	COG0646	methionine synthase
EI981_RS09315	COG1561	YicC-like family, N-terminal region
EI981_RS09320	COG2052	Domain of unknown function (DUF370)
EI981_RS09325	COG0194	GDP metabolic process
EI981_RS09330	COG1758	RNA polymerase activity
EI981_RS09335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EI981_RS09340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EI981_RS09345	COG0242	peptide deformylase activity
EI981_RS09350	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EI981_RS09355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EI981_RS09355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EI981_RS09360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EI981_RS09365	COG0631	protein serine/threonine phosphatase activity
EI981_RS09370	COG0515	serine threonine protein kinase
EI981_RS09370	COG2815	serine threonine protein kinase
EI981_RS09375	COG1162	GTPase activity
EI981_RS09380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EI981_RS09390	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EI981_RS09395	COG1302	Protein conserved in bacteria
EI981_RS09400	COG1461	Dihydroxyacetone kinase
EI981_RS09405	COG1307	EDD domain protein, DegV family
EI981_RS09410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EI981_RS09425	COG0778	Nitroreductase
EI981_RS09430	COG1733	regulation of RNA biosynthetic process
EI981_RS09455	COG0024	Methionine aminopeptidase
EI981_RS09505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EI981_RS09530	COG0673	inositol 2-dehydrogenase activity
EI981_RS09570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EI981_RS09580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI981_RS09590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI981_RS09595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EI981_RS09595	COG1017	nitric oxide dioxygenase activity
EI981_RS09600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI981_RS09600	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI981_RS09605	COG0861	Integral membrane protein TerC family
EI981_RS09620	COG0673	inositol 2-dehydrogenase activity
EI981_RS09625	COG1082	Xylose isomerase domain protein TIM barrel
EI981_RS09630	COG1733	regulation of RNA biosynthetic process
EI981_RS09635	COG0492	ferredoxin-NADP+ reductase activity
EI981_RS09645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI981_RS09650	COG1454	alcohol dehydrogenase
EI981_RS09650	COG1012	belongs to the aldehyde dehydrogenase family
EI981_RS09660	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EI981_RS09685	COG1653	transport
EI981_RS09690	COG1175	transmembrane transport
EI981_RS09695	COG0395	ABC-type sugar transport system, permease component
EI981_RS09700	COG2972	Histidine kinase
EI981_RS09705	COG2207	Transcriptional regulator
EI981_RS09705	COG4753	response regulator
EI981_RS09705	COG2207	Transcriptional regulator
EI981_RS09705	COG4753	response regulator
EI981_RS09710	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS09730	COG0735	belongs to the Fur family
EI981_RS09735	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EI981_RS09740	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI981_RS09740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI981_RS09745	COG3443	Belongs to the bacterial solute-binding protein 9 family
EI981_RS09745	COG0803	Belongs to the bacterial solute-binding protein 9 family
EI981_RS09750	COG1121	(ABC) transporter
EI981_RS09755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EI981_RS09760	COG0785	Cytochrome C biogenesis protein
EI981_RS09765	COG1321	iron dependent repressor
EI981_RS09770	COG1649	PFAM Uncharacterised BCR, COG1649
EI981_RS09775	COG1752	Esterase of the alpha-beta hydrolase superfamily
EI981_RS09785	COG3872	metal-dependent enzyme
EI981_RS09795	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EI981_RS09800	COG0006	proline dipeptidase activity
EI981_RS09805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EI981_RS09820	COG3854	ATPases associated with a variety of cellular activities
EI981_RS09860	COG0511	ligase activity, forming carbon-carbon bonds
EI981_RS09865	COG0439	Biotin carboxylase
EI981_RS09870	COG1302	Protein conserved in bacteria
EI981_RS09885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EI981_RS09890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EI981_RS09895	COG1570	exodeoxyribonuclease VII activity
EI981_RS09900	COG1722	exodeoxyribonuclease VII activity
EI981_RS09905	COG0142	geranyltranstransferase activity
EI981_RS09910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EI981_RS09915	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EI981_RS09925	COG1438	arginine binding
EI981_RS09930	COG0497	DNA recombination
EI981_RS09935	COG0750	zinc metalloprotease
EI981_RS09940	COG0745	RESPONSE REGULATOR receiver
EI981_RS09965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI981_RS09970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EI981_RS09975	COG0022	dehydrogenase e1 component
EI981_RS09980	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI981_RS09985	COG0321	lipoyl(octanoyl) transferase activity
EI981_RS09995	COG2195	Cleaves the N-terminal amino acid of tripeptides
EI981_RS10015	COG1379	DNA repair
EI981_RS10020	COG1300	Membrane
EI981_RS10025	COG0735	belongs to the Fur family
EI981_RS10035	COG4974	Belongs to the 'phage' integrase family
EI981_RS10045	COG1686	Belongs to the peptidase S11 family
EI981_RS10050	COG1366	Belongs to the anti-sigma-factor antagonist family
EI981_RS10055	COG2172	sigma factor antagonist activity
EI981_RS10080	COG0697	spore germination
EI981_RS10085	COG0019	diaminopimelate decarboxylase activity
EI981_RS10090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EI981_RS10100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EI981_RS10100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EI981_RS10110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EI981_RS10110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EI981_RS10115	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EI981_RS10120	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EI981_RS10125	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EI981_RS10135	COG3874	Sporulation protein YtfJ
EI981_RS10140	COG1686	Belongs to the peptidase S11 family
EI981_RS10145	COG2715	membrane protein required for spore maturation
EI981_RS10150	COG0700	Nucleoside recognition
EI981_RS10155	COG1187	pseudouridine synthase activity
EI981_RS10160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI981_RS10165	COG1333	cytochrome c biogenesis protein
EI981_RS10170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EI981_RS10175	COG0745	RESPONSE REGULATOR receiver
EI981_RS10180	COG5002	protein histidine kinase activity
EI981_RS10180	COG5002	protein histidine kinase activity
EI981_RS10185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EI981_RS10205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EI981_RS10215	COG4862	establishment of competence for transformation
EI981_RS10220	COG2339	peptidase activity
EI981_RS10225	COG2959	enzyme of heme biosynthesis
EI981_RS10230	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EI981_RS10250	COG0539	negative regulation of cytoplasmic translation
EI981_RS10255	COG1160	GTP binding
EI981_RS10260	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EI981_RS10295	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EI981_RS10315	COG0142	geranyltranstransferase activity
EI981_RS10320	COG2226	methyltransferase
EI981_RS10325	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EI981_RS10330	COG0163	prenyltransferase activity
EI981_RS10350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EI981_RS10355	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EI981_RS10360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EI981_RS10365	COG4401	Chorismate mutase type I
EI981_RS10375	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EI981_RS10380	COG0134	indole-3-glycerol-phosphate synthase activity
EI981_RS10385	COG0133	tryptophan synthase activity
EI981_RS10390	COG0159	tryptophan synthase activity
EI981_RS10395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EI981_RS10400	COG0287	Prephenate dehydrogenase
EI981_RS10435	COG0588	phosphoglycerate mutase activity
EI981_RS10445	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EI981_RS10475	COG4347	Protein of unknown function (DUF1405)
EI981_RS10485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EI981_RS10490	COG1694	Mazg nucleotide pyrophosphohydrolase
EI981_RS10500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EI981_RS10505	COG1803	Methylglyoxal synthase
EI981_RS10510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EI981_RS10515	COG0438	transferase activity, transferring glycosyl groups
EI981_RS10520	COG0617	tRNA 3'-terminal CCA addition
EI981_RS10530	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EI981_RS10535	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EI981_RS10540	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EI981_RS10550	COG1199	ATP-dependent helicase activity
EI981_RS10550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EI981_RS10555	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EI981_RS10575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EI981_RS10580	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI981_RS10585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EI981_RS10590	COG0017	Asparaginyl-tRNA synthetase
EI981_RS10595	COG3935	DnaD domain protein
EI981_RS10600	COG3397	chitin binding
EI981_RS10640	COG4977	sequence-specific DNA binding
EI981_RS10640	COG1917	Cupin 2, conserved barrel domain protein
EI981_RS10650	COG2376	Dihydroxyacetone kinase
EI981_RS10655	COG0235	Class ii aldolase
EI981_RS10665	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EI981_RS10690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EI981_RS10695	COG0583	DNA-binding transcription factor activity
EI981_RS10705	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EI981_RS10710	COG0066	3-isopropylmalate dehydratase activity
EI981_RS10715	COG0860	N-Acetylmuramoyl-L-alanine amidase
EI981_RS10725	COG0860	N-Acetylmuramoyl-L-alanine amidase
EI981_RS10740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EI981_RS10750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EI981_RS10755	COG1132	(ABC) transporter
EI981_RS10760	COG1132	(ABC) transporter
EI981_RS10765	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EI981_RS10780	COG4753	response regulator
EI981_RS10780	COG2207	Transcriptional regulator
EI981_RS10785	COG2972	Histidine kinase
EI981_RS10805	COG4211	Belongs to the binding-protein-dependent transport system permease family
EI981_RS10810	COG2340	Cysteine-rich secretory protein family
EI981_RS10830	COG1131	(ABC) transporter
EI981_RS10835	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EI981_RS10840	COG0187	DNA topoisomerase II activity
EI981_RS10845	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EI981_RS10865	COG0583	DNA-binding transcription factor activity
EI981_RS10870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EI981_RS10910	COG0745	RESPONSE REGULATOR receiver
EI981_RS10915	COG5002	protein histidine kinase activity
EI981_RS10940	COG1396	sequence-specific DNA binding
EI981_RS10960	COG5520	Belongs to the glycosyl hydrolase 30 family
EI981_RS10970	COG5297	Belongs to the glycosyl hydrolase family 6
EI981_RS10975	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EI981_RS11000	COG0564	pseudouridine synthase activity
EI981_RS11005	COG0116	Belongs to the methyltransferase superfamily
EI981_RS11005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EI981_RS11010	COG1132	(ABC) transporter
EI981_RS11020	COG1119	ATPase activity
EI981_RS11025	COG0330	HflC and HflK could
EI981_RS11045	COG0697	spore germination
EI981_RS11075	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EI981_RS11080	COG0288	reversible hydration of carbon dioxide
EI981_RS11110	COG1175	transmembrane transport
EI981_RS11115	COG0395	ABC-type sugar transport system, permease component
EI981_RS11125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EI981_RS11135	COG1069	ribulokinase activity
EI981_RS11150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EI981_RS11155	COG1116	anion transmembrane transporter activity
EI981_RS11160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EI981_RS11165	COG4129	membrane
EI981_RS11180	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EI981_RS11185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EI981_RS11190	COG2521	methyltransferase
EI981_RS11190	COG2136	Putative SAM-dependent methyltransferase
EI981_RS11200	COG1923	regulation of RNA biosynthetic process
EI981_RS11205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EI981_RS11220	COG0464	growth
EI981_RS11225	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EI981_RS11230	COG0789	Transcriptional regulator
EI981_RS11235	COG0174	glutamine synthetase
EI981_RS11245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EI981_RS11255	COG4224	UPF0291 protein
EI981_RS11265	COG1011	Hydrolase
EI981_RS11275	COG1410	methionine synthase
EI981_RS11275	COG0646	methionine synthase
EI981_RS11280	COG1234	tRNA 3'-trailer cleavage
EI981_RS11285	COG0647	UMP catabolic process
EI981_RS11295	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EI981_RS11305	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EI981_RS11310	COG2815	serine threonine protein kinase
EI981_RS11310	COG0515	serine threonine protein kinase
EI981_RS11370	COG0488	(ABC) transporter
EI981_RS11375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EI981_RS11380	COG0745	RESPONSE REGULATOR receiver
EI981_RS11385	COG0791	NLP P60 protein
EI981_RS11395	COG2860	membrane
EI981_RS11425	COG0768	penicillin binding
EI981_RS11435	COG2076	Multidrug Resistance protein
EI981_RS11440	COG2076	Multidrug Resistance protein
EI981_RS11490	COG1968	undecaprenyl-diphosphatase activity
EI981_RS11495	COG1660	Displays ATPase and GTPase activities
EI981_RS11500	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EI981_RS11505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EI981_RS11510	COG0493	'glutamate synthase
EI981_RS11530	COG0477	Major facilitator Superfamily
EI981_RS11535	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EI981_RS11545	COG0745	RESPONSE REGULATOR receiver
EI981_RS11550	COG5002	protein histidine kinase activity
EI981_RS11555	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EI981_RS11560	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EI981_RS11565	COG0297	glycogen (starch) synthase activity
EI981_RS11575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EI981_RS11580	COG0765	amino acid transport
EI981_RS11585	COG1126	abc transporter atp-binding protein
EI981_RS11590	COG3584	3D domain protein
EI981_RS11590	COG1388	LysM domain
EI981_RS11600	COG0543	2 iron, 2 sulfur cluster binding
EI981_RS11605	COG0167	dihydroorotate dehydrogenase activity
EI981_RS11615	COG0303	'Molybdopterin
EI981_RS11625	COG4974	Belongs to the 'phage' integrase family
EI981_RS11635	COG1846	Transcriptional regulator
EI981_RS11640	COG2814	Major facilitator Superfamily
EI981_RS11650	COG0697	spore germination
EI981_RS11655	COG0531	amino acid
EI981_RS11670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EI981_RS11675	COG2226	methyltransferase
EI981_RS11680	COG0039	L-malate dehydrogenase activity
EI981_RS11710	COG3773	Cell wall hydrolase
EI981_RS11720	COG1253	flavin adenine dinucleotide binding
EI981_RS11730	COG0747	negative chemotaxis
EI981_RS11735	COG0601	transmembrane transport
EI981_RS11740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI981_RS11745	COG0444	Belongs to the ABC transporter superfamily
EI981_RS11750	COG4608	Belongs to the ABC transporter superfamily
EI981_RS11755	COG2309	aminopeptidase activity
EI981_RS11760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EI981_RS11770	COG0628	permease
EI981_RS11785	COG1959	2 iron, 2 sulfur cluster binding
EI981_RS11790	COG0745	RESPONSE REGULATOR receiver
EI981_RS11795	COG5002	protein histidine kinase activity
EI981_RS11800	COG1136	(ABC) transporter
EI981_RS11805	COG0577	efflux transmembrane transporter activity
EI981_RS11810	COG2514	catechol 2,3-dioxygenase activity
EI981_RS11815	COG2910	NAD(P)H-binding
EI981_RS11820	COG1175	transmembrane transport
EI981_RS11825	COG0395	ABC-type sugar transport system, permease component
EI981_RS11835	COG2972	Histidine kinase
EI981_RS11850	COG0789	Transcriptional regulator
EI981_RS11890	COG0406	alpha-ribazole phosphatase activity
EI981_RS11915	COG0745	RESPONSE REGULATOR receiver
EI981_RS11920	COG5002	protein histidine kinase activity
EI981_RS11930	COG0671	phosphoesterase, PA-phosphatase related
EI981_RS11955	COG2972	Histidine kinase
EI981_RS11960	COG2204	response regulator
EI981_RS11970	COG4209	transmembrane transport
EI981_RS11975	COG0395	ABC-type sugar transport system, permease component
EI981_RS12005	COG4209	transmembrane transport
EI981_RS12010	COG0395	ABC-type sugar transport system, permease component
EI981_RS12020	COG3279	Response regulator of the LytR AlgR family
EI981_RS12025	COG2972	Histidine kinase
EI981_RS12035	COG2814	Major facilitator Superfamily
EI981_RS12040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EI981_RS12060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS12070	COG2375	cellular response to nickel ion
EI981_RS12070	COG1132	(ABC) transporter
EI981_RS12080	COG4716	Myosin-crossreactive antigen
EI981_RS12090	COG0596	Alpha beta hydrolase
EI981_RS12095	COG2207	Transcriptional regulator
EI981_RS12095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS12100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS12105	COG2819	hydrolase of the alpha beta superfamily
EI981_RS12110	COG1757	Na H antiporter
EI981_RS12130	COG1902	pentaerythritol trinitrate reductase activity
EI981_RS12135	COG1733	regulation of RNA biosynthetic process
EI981_RS12150	COG3711	transcriptional antiterminator
EI981_RS12155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI981_RS12160	COG0246	Mannitol dehydrogenase
EI981_RS12170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI981_RS12170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EI981_RS12175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS12185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS12190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI981_RS12195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI981_RS12205	COG0765	amino acid transport
EI981_RS12215	COG2720	vancomycin resistance protein
EI981_RS12220	COG0840	transmembrane signaling receptor activity
EI981_RS12225	COG0840	transmembrane signaling receptor activity
EI981_RS12235	COG2814	Major facilitator Superfamily
EI981_RS12245	COG0583	DNA-binding transcription factor activity
EI981_RS12250	COG3842	ATPase activity
EI981_RS12260	COG1177	transmembrane transport
EI981_RS12270	COG1216	Glycosyl transferase, family 2
EI981_RS12300	COG0456	acetyltransferase
EI981_RS12320	COG0733	neurotransmitter:sodium symporter activity
EI981_RS12330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI981_RS12335	COG0095	Lipoate-protein ligase
EI981_RS12340	COG0095	Lipoate-protein ligase
EI981_RS12350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI981_RS12370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EI981_RS12375	COG0492	ferredoxin-NADP+ reductase activity
EI981_RS12380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS12405	COG1131	(ABC) transporter
EI981_RS12415	COG1113	amino acid transport
EI981_RS12420	COG1280	lysine exporter protein (LysE YggA)
EI981_RS12425	COG5002	protein histidine kinase activity
EI981_RS12430	COG0745	RESPONSE REGULATOR receiver
EI981_RS12435	COG1183	phosphatidylcholine synthase activity
EI981_RS12440	COG0586	Pfam SNARE associated Golgi protein
EI981_RS12445	COG0572	uridine kinase
EI981_RS12450	COG1051	belongs to the nudix hydrolase family
EI981_RS12475	COG0456	acetyltransferase
EI981_RS12485	COG2801	Transposase and inactivated derivatives
EI981_RS12490	COG2963	transposase activity
EI981_RS12500	COG2205	protein histidine kinase activity
EI981_RS12505	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EI981_RS12525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI981_RS12530	COG1120	ATPase activity
EI981_RS12535	COG0477	Major facilitator Superfamily
EI981_RS12545	COG1280	lysine exporter protein (LysE YggA)
EI981_RS12555	COG0583	DNA-binding transcription factor activity
EI981_RS12570	COG1175	transmembrane transport
EI981_RS12575	COG0395	ABC-type sugar transport system, permease component
EI981_RS12595	COG5002	protein histidine kinase activity
EI981_RS12600	COG0028	Belongs to the TPP enzyme family
EI981_RS12605	COG3878	Protein conserved in bacteria
EI981_RS12610	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS12615	COG2972	Histidine kinase
EI981_RS12615	COG0745	RESPONSE REGULATOR receiver
EI981_RS12635	COG0477	Major facilitator Superfamily
EI981_RS12640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI981_RS12650	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EI981_RS12650	COG0456	acetyltransferase
EI981_RS12660	COG0778	Nitroreductase
EI981_RS12665	COG1595	DNA-templated transcription, initiation
EI981_RS12680	COG2378	regulation of single-species biofilm formation
EI981_RS12690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS12700	COG0436	Aminotransferase
EI981_RS12710	COG0431	NADPH-dependent FMN reductase
EI981_RS12720	COG1959	2 iron, 2 sulfur cluster binding
EI981_RS12760	COG0561	phosphatase activity
EI981_RS12765	COG0738	Major facilitator superfamily
EI981_RS12770	COG1609	Transcriptional regulator
EI981_RS12775	COG1819	glycosyl
EI981_RS12780	COG2304	oxidoreductase activity
EI981_RS12785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EI981_RS12800	COG4941	Belongs to the sigma-70 factor family
EI981_RS12825	COG2076	Multidrug Resistance protein
EI981_RS12830	COG2076	Multidrug Resistance protein
EI981_RS12835	COG2244	polysaccharide biosynthetic process
EI981_RS12845	COG4335	DNA alkylation repair
EI981_RS12855	COG1349	DNA-binding transcription factor activity
EI981_RS12860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EI981_RS12905	COG2207	Transcriptional regulator
EI981_RS12910	COG4209	transmembrane transport
EI981_RS12915	COG0395	ABC-type sugar transport system, permease component
EI981_RS12920	COG1653	transport
EI981_RS12930	COG0445	tRNA wobble uridine modification
EI981_RS12945	COG0110	maltose O-acetyltransferase activity
EI981_RS12955	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EI981_RS12965	COG3340	Belongs to the peptidase S51 family
EI981_RS12970	COG0753	catalase activity
EI981_RS12975	COG3973	AAA domain
EI981_RS12985	COG0745	RESPONSE REGULATOR receiver
EI981_RS12990	COG5002	protein histidine kinase activity
EI981_RS13010	COG1696	Membrane protein involved in D-alanine export
EI981_RS13030	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EI981_RS13070	COG0640	Transcriptional regulator
EI981_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS13090	COG0640	Transcriptional regulator
EI981_RS13095	COG0798	PFAM Bile acid sodium symporter
EI981_RS13100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EI981_RS13105	COG0534	Mate efflux family protein
EI981_RS13140	COG0531	amino acid
EI981_RS13150	COG0351	phosphomethylpyrimidine kinase
EI981_RS13155	COG1757	Na H antiporter
EI981_RS13160	COG0582	viral genome integration into host DNA
EI981_RS13165	COG2856	Zn peptidase
EI981_RS13180	COG1396	sequence-specific DNA binding
EI981_RS13210	COG2002	toxin-antitoxin pair type II binding
EI981_RS13265	COG1522	sequence-specific DNA binding
EI981_RS13275	COG0305	Participates in initiation and elongation during chromosome replication
EI981_RS13285	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EI981_RS13305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EI981_RS13365	COG1783	phage Terminase large subunit
EI981_RS13440	COG2823	Periplasmic or secreted lipoprotein
EI981_RS13440	COG1652	LysM domain
EI981_RS13460	COG3299	homolog of phage Mu protein gp47
EI981_RS13515	COG2135	peptidase activity
EI981_RS13530	COG4496	protein, YerC YecD
EI981_RS13535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS13555	COG1131	(ABC) transporter
EI981_RS13580	COG1266	CAAX protease self-immunity
EI981_RS13590	COG1959	2 iron, 2 sulfur cluster binding
EI981_RS13600	COG0492	ferredoxin-NADP+ reductase activity
EI981_RS13625	COG0110	maltose O-acetyltransferase activity
EI981_RS13630	COG1051	belongs to the nudix hydrolase family
EI981_RS13635	COG1609	Transcriptional regulator
EI981_RS13645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EI981_RS13660	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
EI981_RS13660	COG0028	Belongs to the TPP enzyme family
EI981_RS13715	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EI981_RS13735	COG1733	regulation of RNA biosynthetic process
EI981_RS13745	COG0789	Transcriptional regulator
EI981_RS13750	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS13825	COG2226	methyltransferase
EI981_RS13865	COG0745	RESPONSE REGULATOR receiver
EI981_RS13895	COG0601	transmembrane transport
EI981_RS13900	COG2199	diguanylate cyclase activity
EI981_RS13900	COG2203	Gaf domain
EI981_RS13915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS13945	COG2814	Major facilitator Superfamily
EI981_RS13970	COG0596	Alpha beta hydrolase
EI981_RS13980	COG4978	Transcriptional regulator
EI981_RS13980	COG0789	Transcriptional regulator
EI981_RS14010	COG0583	DNA-binding transcription factor activity
EI981_RS14015	COG2807	transmembrane transport
EI981_RS14020	COG1595	DNA-templated transcription, initiation
EI981_RS14030	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EI981_RS14055	COG5002	protein histidine kinase activity
EI981_RS14080	COG1595	DNA-templated transcription, initiation
EI981_RS14105	COG1175	transmembrane transport
EI981_RS14135	COG1595	DNA-templated transcription, initiation
EI981_RS14160	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS14175	COG0561	phosphatase activity
EI981_RS14180	COG3394	polysaccharide catabolic process
EI981_RS14185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EI981_RS14190	COG1834	amidinotransferase
EI981_RS14205	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS14220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EI981_RS14270	COG0745	RESPONSE REGULATOR receiver
EI981_RS14275	COG2205	protein histidine kinase activity
EI981_RS14290	COG2608	mercury ion transmembrane transporter activity
EI981_RS14300	COG2217	Heavy metal translocating P-type atpase
EI981_RS14325	COG1131	(ABC) transporter
EI981_RS14355	COG5002	protein histidine kinase activity
EI981_RS14355	COG3850	Histidine kinase
EI981_RS14390	COG1309	transcriptional regulator
EI981_RS14395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS14395	COG3320	Male sterility
EI981_RS14400	COG0789	Transcriptional regulator
EI981_RS14415	COG3655	Transcriptional regulator
EI981_RS14425	COG1309	transcriptional regulator
EI981_RS14460	COG0789	Transcriptional regulator
EI981_RS14470	COG2249	NAD(P)H dehydrogenase (quinone) activity
EI981_RS14490	COG5002	protein histidine kinase activity
EI981_RS14495	COG0745	RESPONSE REGULATOR receiver
EI981_RS14545	COG3397	chitin binding
EI981_RS14575	COG0477	Major facilitator Superfamily
EI981_RS14585	COG1959	2 iron, 2 sulfur cluster binding
EI981_RS14615	COG1132	(ABC) transporter
EI981_RS14625	COG1846	Transcriptional regulator
EI981_RS14630	COG5002	protein histidine kinase activity
EI981_RS14630	COG3850	Histidine kinase
EI981_RS14640	COG1136	(ABC) transporter
EI981_RS14640	COG0577	efflux transmembrane transporter activity
EI981_RS14655	COG0789	Transcriptional regulator
EI981_RS14665	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS14745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI981_RS14765	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EI981_RS14770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI981_RS14775	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EI981_RS14780	COG1733	regulation of RNA biosynthetic process
EI981_RS14800	COG0719	Fe-S assembly protein
EI981_RS14805	COG0719	Fe-S assembly protein
EI981_RS14810	COG0396	ATPase activity
EI981_RS14815	COG1846	Transcriptional regulator
EI981_RS14820	COG0778	Nitroreductase
EI981_RS14845	COG0653	protein targeting
EI981_RS14860	COG3279	Response regulator of the LytR AlgR family
EI981_RS14865	COG3118	belongs to the thioredoxin family
EI981_RS14875	COG0574	Belongs to the PEP-utilizing enzyme family
EI981_RS14875	COG3848	Pyruvate phosphate dikinase
EI981_RS14920	COG1876	peptidase activity
EI981_RS14940	COG2226	methyltransferase
EI981_RS14950	COG0596	Alpha beta hydrolase
EI981_RS14990	COG1902	pentaerythritol trinitrate reductase activity
EI981_RS14995	COG0583	DNA-binding transcription factor activity
EI981_RS15005	COG0438	transferase activity, transferring glycosyl groups
EI981_RS15015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EI981_RS15020	COG0778	Nitroreductase
EI981_RS15025	COG1846	Transcriptional regulator
EI981_RS15030	COG0488	(ABC) transporter
EI981_RS15045	COG4149	molybdate abc transporter
EI981_RS15050	COG0725	ABC transporter, periplasmic molybdate-binding protein
EI981_RS15065	COG4166	transmembrane transport
EI981_RS15070	COG0601	transmembrane transport
EI981_RS15075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI981_RS15080	COG0444	Belongs to the ABC transporter superfamily
EI981_RS15085	COG4608	Belongs to the ABC transporter superfamily
EI981_RS15125	COG0443	Heat shock 70 kDa protein
EI981_RS15130	COG0110	maltose O-acetyltransferase activity
EI981_RS15135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS15140	COG0697	spore germination
EI981_RS15160	COG0346	lactoylglutathione lyase activity
EI981_RS15165	COG1846	Transcriptional regulator
EI981_RS15175	COG1175	transmembrane transport
EI981_RS15180	COG0395	ABC-type sugar transport system, permease component
EI981_RS15185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS15190	COG0454	-acetyltransferase
EI981_RS15195	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EI981_RS15200	COG0628	permease
EI981_RS15205	COG0477	Major facilitator Superfamily
EI981_RS15210	COG1846	Transcriptional regulator
EI981_RS15215	COG4974	Belongs to the 'phage' integrase family
EI981_RS15220	COG1396	sequence-specific DNA binding
EI981_RS15225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EI981_RS15235	COG0517	IMP dehydrogenase activity
EI981_RS15240	COG2205	protein histidine kinase activity
EI981_RS15245	COG0745	RESPONSE REGULATOR receiver
EI981_RS15260	COG0577	efflux transmembrane transporter activity
EI981_RS15265	COG1136	(ABC) transporter
EI981_RS15270	COG2239	Acts as a magnesium transporter
EI981_RS15275	COG2239	Acts as a magnesium transporter
EI981_RS15280	COG0772	Belongs to the SEDS family
EI981_RS15310	COG0772	Belongs to the SEDS family
EI981_RS15320	COG5002	protein histidine kinase activity
EI981_RS15325	COG0745	RESPONSE REGULATOR receiver
EI981_RS15330	COG1309	transcriptional regulator
EI981_RS15340	COG1131	(ABC) transporter
EI981_RS15360	COG1131	(ABC) transporter
EI981_RS15380	COG0561	phosphatase activity
EI981_RS15390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EI981_RS15395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EI981_RS15400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EI981_RS15425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EI981_RS15430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EI981_RS15445	COG4753	response regulator
EI981_RS15445	COG2207	Transcriptional regulator
EI981_RS15450	COG2972	Histidine kinase
EI981_RS15455	COG3833	ABC-type maltose transport systems, permease component
EI981_RS15460	COG1175	transmembrane transport
EI981_RS15470	COG2814	Major facilitator Superfamily
EI981_RS15475	COG1132	(ABC) transporter
EI981_RS15485	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI981_RS15490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EI981_RS15500	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS15505	COG0109	protoheme IX farnesyltransferase activity
EI981_RS15525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EI981_RS15530	COG0314	molybdopterin synthase activity
EI981_RS15545	COG0546	phosphoglycolate phosphatase activity
EI981_RS15550	COG0583	DNA-binding transcription factor activity
EI981_RS15565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EI981_RS15570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EI981_RS15575	COG1982	Orn Lys Arg decarboxylase major
EI981_RS15590	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EI981_RS15595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EI981_RS15600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS15615	COG3135	benzoate transporter
EI981_RS15620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EI981_RS15625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EI981_RS15630	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EI981_RS15635	COG0626	cystathionine gamma-synthase activity
EI981_RS15640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EI981_RS15645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EI981_RS15650	COG2258	MOSC domain
EI981_RS15655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS15665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EI981_RS15675	COG0442	prolyl-tRNA aminoacylation
EI981_RS15680	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EI981_RS15685	COG0789	Transcriptional regulator
EI981_RS15700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EI981_RS15715	COG2032	superoxide dismutase activity
EI981_RS15720	COG0673	inositol 2-dehydrogenase activity
EI981_RS15735	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EI981_RS15740	COG2814	Major facilitator Superfamily
EI981_RS15745	COG2378	regulation of single-species biofilm formation
EI981_RS15750	COG1201	RNA secondary structure unwinding
EI981_RS15770	COG2223	nitrite transmembrane transporter activity
EI981_RS15785	COG1131	(ABC) transporter
EI981_RS15795	COG2226	methyltransferase
EI981_RS15810	COG2814	Major facilitator Superfamily
EI981_RS15825	COG3832	glyoxalase III activity
EI981_RS15830	COG0667	Aldo Keto reductase
EI981_RS15840	COG2267	carboxylic ester hydrolase activity
EI981_RS15850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EI981_RS15870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EI981_RS15875	COG1309	transcriptional regulator
EI981_RS15880	COG0666	response to abiotic stimulus
EI981_RS15940	COG1131	(ABC) transporter
EI981_RS15955	COG0318	PFAM AMP-dependent synthetase and ligase
EI981_RS15960	COG1960	acyl-CoA dehydrogenase activity
EI981_RS15965	COG0183	Belongs to the thiolase family
EI981_RS15970	COG1024	Enoyl-CoA hydratase
EI981_RS15970	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI981_RS15975	COG0247	lactate metabolic process
EI981_RS15975	COG2181	nitrate reductase activity
EI981_RS15980	COG1309	transcriptional regulator
EI981_RS15985	COG2086	electron transfer activity
EI981_RS15990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EI981_RS15995	COG1263	PTS System
EI981_RS15995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EI981_RS15995	COG2190	(PTS) system
EI981_RS16035	COG2076	Multidrug Resistance protein
EI981_RS16040	COG2076	Multidrug Resistance protein
EI981_RS16045	COG1902	pentaerythritol trinitrate reductase activity
EI981_RS16050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EI981_RS16055	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EI981_RS16060	COG0693	protein deglycase activity
EI981_RS16075	COG2378	regulation of single-species biofilm formation
EI981_RS16110	COG2205	protein histidine kinase activity
EI981_RS16120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EI981_RS16125	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EI981_RS16135	COG4978	Transcriptional regulator
EI981_RS16135	COG0789	Transcriptional regulator
EI981_RS16140	COG2814	Major facilitator Superfamily
EI981_RS16150	COG0477	Major facilitator Superfamily
EI981_RS16160	COG1247	-acetyltransferase
EI981_RS16175	COG1122	ATPase activity
EI981_RS16180	COG4120	Belongs to the binding-protein-dependent transport system permease family
EI981_RS16200	COG2814	Major facilitator Superfamily
EI981_RS16215	COG1653	transport
EI981_RS16220	COG0395	ABC-type sugar transport system, permease component
EI981_RS16225	COG4209	transmembrane transport
EI981_RS16230	COG2207	Transcriptional regulator
EI981_RS16230	COG4753	response regulator
EI981_RS16235	COG2972	Histidine kinase
EI981_RS16260	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EI981_RS16270	COG3976	FMN-binding domain protein
EI981_RS16270	COG1053	succinate dehydrogenase
EI981_RS16280	COG1011	Hydrolase
EI981_RS16285	COG2340	Cysteine-rich secretory protein family
EI981_RS16315	COG4977	sequence-specific DNA binding
EI981_RS16315	COG1917	Cupin 2, conserved barrel domain protein
EI981_RS16320	COG2312	Erythromycin esterase
EI981_RS16335	COG2059	Chromate
EI981_RS16345	COG0583	DNA-binding transcription factor activity
EI981_RS16350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS16355	COG2207	Transcriptional regulator
EI981_RS16360	COG1733	regulation of RNA biosynthetic process
EI981_RS16365	COG0667	Aldo Keto reductase
EI981_RS16380	COG1126	abc transporter atp-binding protein
EI981_RS16390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EI981_RS16395	COG0435	Glutathione S-transferase
EI981_RS16400	COG0435	Glutathione S-transferase
EI981_RS16405	COG0456	acetyltransferase
EI981_RS16420	COG2801	Transposase and inactivated derivatives
EI981_RS16425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EI981_RS16430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI981_RS16435	COG4821	SIS domain
EI981_RS16445	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EI981_RS16460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI981_RS16465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI981_RS16465	COG3711	transcriptional antiterminator
EI981_RS16485	COG3588	fructose-bisphosphate aldolase
EI981_RS16490	COG4129	membrane
EI981_RS16500	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EI981_RS16515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EI981_RS16535	COG2323	membrane
EI981_RS16545	COG0252	asparaginase activity
EI981_RS16550	COG1785	Belongs to the alkaline phosphatase family
EI981_RS16560	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EI981_RS16590	COG2814	Major facilitator Superfamily
EI981_RS16660	COG2814	Major facilitator Superfamily
EI981_RS16675	COG1486	melibiose metabolic process
EI981_RS16680	COG2207	Transcriptional regulator
EI981_RS16685	COG0322	excinuclease ABC activity
EI981_RS16705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI981_RS16750	COG0395	ABC-type sugar transport system, permease component
EI981_RS16755	COG1175	transmembrane transport
EI981_RS16760	COG2972	Histidine kinase
EI981_RS16785	COG0395	ABC-type sugar transport system, permease component
EI981_RS16790	COG1175	transmembrane transport
EI981_RS16820	COG2207	Transcriptional regulator
EI981_RS16820	COG4753	response regulator
EI981_RS16825	COG2972	Histidine kinase
EI981_RS16830	COG0395	ABC-type sugar transport system, permease component
EI981_RS16835	COG1175	transmembrane transport
EI981_RS16845	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EI981_RS16855	COG2801	Transposase and inactivated derivatives
EI981_RS16880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EI981_RS16905	COG2814	Major facilitator Superfamily
EI981_RS16930	COG3739	integral membrane protein
EI981_RS16960	COG5002	protein histidine kinase activity
EI981_RS16970	COG1132	(ABC) transporter
EI981_RS16975	COG1285	pathogenesis
EI981_RS16995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EI981_RS17010	COG2197	response regulator
EI981_RS17015	COG4585	Histidine kinase
EI981_RS17020	COG0772	Belongs to the SEDS family
EI981_RS17025	COG1263	PTS System
EI981_RS17025	COG2190	(PTS) system
EI981_RS17025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EI981_RS17030	COG2190	(PTS) system
EI981_RS17050	COG1643	Atp-dependent helicase
EI981_RS17055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI981_RS17070	COG1131	(ABC) transporter
EI981_RS17075	COG1725	Transcriptional regulator
EI981_RS17095	COG1011	Hydrolase
EI981_RS17105	COG0492	ferredoxin-NADP+ reductase activity
EI981_RS17110	COG2707	UPF0756 membrane protein
EI981_RS17115	COG1418	mRNA catabolic process
EI981_RS17120	COG1132	(ABC) transporter
EI981_RS17135	COG4841	protein insertion into membrane
EI981_RS17140	COG1132	(ABC) transporter
EI981_RS17145	COG1132	(ABC) transporter
EI981_RS17150	COG0477	Major facilitator Superfamily
EI981_RS17155	COG1309	transcriptional regulator
EI981_RS17170	COG0110	maltose O-acetyltransferase activity
EI981_RS17190	COG2135	peptidase activity
EI981_RS17230	COG0523	cobalamin synthesis protein
EI981_RS17235	COG0521	Mo-molybdopterin cofactor biosynthetic process
EI981_RS17245	COG0346	lactoylglutathione lyase activity
EI981_RS17250	COG0154	amidase activity
EI981_RS17275	COG4106	trans-aconitate 2-methyltransferase activity
EI981_RS17280	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS17335	COG0604	alcohol dehydrogenase
EI981_RS17340	COG0674	pyruvate-flavodoxin oxidoreductase activity
EI981_RS17350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EI981_RS17365	COG4550	Control of competence regulator ComK, YlbF/YmcA
EI981_RS17370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI981_RS17380	COG2323	membrane
EI981_RS17390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI981_RS17395	COG4869	propanediol catabolic process
EI981_RS17400	COG1013	pyruvate-flavodoxin oxidoreductase activity
EI981_RS17405	COG0674	pyruvate-flavodoxin oxidoreductase activity
EI981_RS17405	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EI981_RS17415	COG2359	stage V sporulation protein S
EI981_RS17420	COG1692	metallophosphoesterase
EI981_RS17425	COG1418	mRNA catabolic process
EI981_RS17430	COG2137	regulation of response to DNA damage stimulus
EI981_RS17435	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EI981_RS17445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EI981_RS17450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI981_RS17460	COG1426	Protein conserved in bacteria
EI981_RS17475	COG0300	oxidoreductase activity
EI981_RS17480	COG0612	Peptidase, M16
EI981_RS17485	COG0612	Peptidase, M16
EI981_RS17495	COG1674	ftsk spoiiie
EI981_RS17495	COG4980	gas vesicle protein
EI981_RS17505	COG0740	serine-type endopeptidase activity
EI981_RS17510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EI981_RS17515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EI981_RS17520	COG0527	aspartate kinase activity
EI981_RS17530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EI981_RS17535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EI981_RS17540	COG0756	dUTP diphosphatase activity
EI981_RS17545	COG0612	Peptidase, M16
EI981_RS17550	COG0726	polysaccharide deacetylase
EI981_RS17555	COG2274	protein secretion by the type I secretion system
EI981_RS17560	COG1132	(ABC) transporter
EI981_RS17565	COG1185	polyribonucleotide nucleotidyltransferase activity
EI981_RS17570	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EI981_RS17575	COG0196	riboflavin kinase activity
EI981_RS17580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EI981_RS17585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EI981_RS17590	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EI981_RS17595	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EI981_RS17600	COG1358	cellular component organization or biogenesis
EI981_RS17605	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EI981_RS17615	COG0195	Participates in both transcription termination and antitermination
EI981_RS17620	COG0779	Required for maturation of 30S ribosomal subunits
EI981_RS17625	COG2176	DNA-directed DNA polymerase activity
EI981_RS17630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EI981_RS17635	COG0750	zinc metalloprotease
EI981_RS17640	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EI981_RS17645	COG4589	Belongs to the CDS family
EI981_RS17655	COG0233	cytoplasmic translational termination
EI981_RS17660	COG0528	UMP kinase activity
EI981_RS17665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EI981_RS17670	COG0052	Belongs to the universal ribosomal protein uS2 family
EI981_RS17700	COG1191	sigma factor activity
EI981_RS17710	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EI981_RS17715	COG1776	CheC inhibitor of MCP methylation
EI981_RS17720	COG0835	chemotaxis
EI981_RS17725	COG2198	Histidine kinase
EI981_RS17725	COG0643	Histidine kinase
EI981_RS17730	COG2201	protein-glutamate methylesterase activity
EI981_RS17735	COG0455	bacterial-type flagellum organization
EI981_RS17740	COG1419	protein localization to endoplasmic reticulum
EI981_RS17745	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EI981_RS17750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EI981_RS17755	COG1684	flagellar biosynthetic protein fliR
EI981_RS17760	COG1987	bacterial-type flagellum assembly
EI981_RS17765	COG1338	Plays a role in the flagellum-specific transport system
EI981_RS17770	COG3190	flagellar
EI981_RS17775	COG2201	protein-glutamate methylesterase activity
EI981_RS17780	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EI981_RS17780	COG1776	CheC inhibitor of MCP methylation
EI981_RS17785	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EI981_RS17800	COG4786	Flagellar basal body rod
EI981_RS17810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EI981_RS17830	COG1157	protein secretion by the type III secretion system
EI981_RS17840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EI981_RS17845	COG1766	The M ring may be actively involved in energy transduction
EI981_RS17850	COG1677	Flagellar hook-basal body complex protein FliE
EI981_RS17855	COG1558	bacterial-type flagellum-dependent cell motility
EI981_RS17865	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EI981_RS17870	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EI981_RS17875	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EI981_RS17880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EI981_RS17885	COG0758	DNA mediated transformation
EI981_RS17890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EI981_RS17895	COG0045	succinate-CoA ligase (ADP-forming) activity
EI981_RS17905	COG0792	nuclease activity
EI981_RS17910	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EI981_RS17920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EI981_RS17930	COG0681	Belongs to the peptidase S26 family
EI981_RS17935	COG0335	large ribosomal subunit rRNA binding
EI981_RS17955	COG0726	polysaccharide deacetylase
EI981_RS17960	COG0336	Belongs to the RNA methyltransferase TrmD family
EI981_RS17970	COG1837	Belongs to the UPF0109 family
EI981_RS17975	COG0228	four-way junction DNA binding
EI981_RS17980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EI981_RS17990	COG1272	protein, Hemolysin III
EI981_RS17995	COG0552	protein localization to endoplasmic reticulum
EI981_RS18000	COG1196	nuclear chromosome segregation
EI981_RS18005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EI981_RS18010	COG0571	ribonuclease III activity
EI981_RS18015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EI981_RS18020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS18025	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS18030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EI981_RS18035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI981_RS18040	COG0416	fatty acid biosynthetic process
EI981_RS18050	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EI981_RS18060	COG1323	Belongs to the UPF0348 family
EI981_RS18065	COG3480	Lon protease (S16) C-terminal proteolytic domain
EI981_RS18070	COG3314	Sporulation integral membrane protein YlbJ
EI981_RS18075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EI981_RS18080	COG0742	ribosomal rna small subunit methyltransferase
EI981_RS18085	COG5426	von Willebrand factor, type A
EI981_RS18090	COG0588	phosphoglycerate mutase activity
EI981_RS18105	COG1033	growth of symbiont in host cell
EI981_RS18105	COG2409	Drug exporters of the RND superfamily
EI981_RS18110	COG1846	Transcriptional regulator
EI981_RS18120	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EI981_RS18125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EI981_RS18130	COG2814	Major facilitator Superfamily
EI981_RS18135	COG3973	AAA domain
EI981_RS18150	COG4129	membrane
EI981_RS18160	COG0628	permease
EI981_RS18165	COG1605	Chorismate mutase
EI981_RS18165	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EI981_RS18170	COG2706	6-phosphogluconolactonase activity
EI981_RS18185	COG3103	Sh3 type 3 domain protein
EI981_RS18185	COG1388	LysM domain
EI981_RS18185	COG0791	NLP P60 protein
EI981_RS18195	COG1609	Transcriptional regulator
EI981_RS18200	COG3459	Glycosyltransferase 36 associated
EI981_RS18205	COG1649	PFAM Uncharacterised BCR, COG1649
EI981_RS18210	COG2814	Major facilitator Superfamily
EI981_RS18215	COG0840	transmembrane signaling receptor activity
EI981_RS18250	COG1132	(ABC) transporter
EI981_RS18255	COG2207	Transcriptional regulator
EI981_RS18275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI981_RS18285	COG2226	methyltransferase
EI981_RS18295	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EI981_RS18300	COG0456	acetyltransferase
EI981_RS18305	COG0778	Nitroreductase
EI981_RS18310	COG1619	proteins homologs of microcin C7 resistance protein MccF
EI981_RS18325	COG0673	inositol 2-dehydrogenase activity
EI981_RS18345	COG1136	(ABC) transporter
EI981_RS18360	COG1136	(ABC) transporter
EI981_RS18360	COG0577	efflux transmembrane transporter activity
EI981_RS18370	COG2814	Major facilitator Superfamily
EI981_RS18375	COG1309	transcriptional regulator
EI981_RS18380	COG1011	Hydrolase
EI981_RS18390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI981_RS18400	COG0395	ABC-type sugar transport system, permease component
EI981_RS18405	COG1175	transmembrane transport
EI981_RS18415	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EI981_RS18435	COG1175	transmembrane transport
EI981_RS18440	COG5002	protein histidine kinase activity
EI981_RS18445	COG0745	RESPONSE REGULATOR receiver
EI981_RS18455	COG1840	ABC-type Fe3 transport system, periplasmic component
EI981_RS18460	COG3842	ATPase activity
EI981_RS18465	COG1178	ABC-type Fe3 transport system permease component
EI981_RS18490	COG1733	regulation of RNA biosynthetic process
EI981_RS18495	COG0778	Nitroreductase
EI981_RS18500	COG0640	Transcriptional regulator
EI981_RS18525	COG1733	regulation of RNA biosynthetic process
EI981_RS18540	COG0583	DNA-binding transcription factor activity
EI981_RS18565	COG0667	Aldo Keto reductase
EI981_RS18585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EI981_RS18590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EI981_RS18610	COG0860	N-Acetylmuramoyl-L-alanine amidase
EI981_RS18610	COG2247	cell wall binding repeat
EI981_RS18615	COG2861	carbohydrate metabolic process
EI981_RS18625	COG1940	carbohydrate kinase activity
EI981_RS18630	COG2226	methyltransferase
EI981_RS18635	COG0383	alpha-mannosidase activity
EI981_RS18655	COG2207	Transcriptional regulator
EI981_RS18665	COG1279	arginine transmembrane transporter activity
EI981_RS18670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS18690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EI981_RS18695	COG1353	crispr-associated protein
EI981_RS18695	COG0617	tRNA 3'-terminal CCA addition
EI981_RS18705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI981_RS18710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS18715	COG1612	heme a metabolic process
EI981_RS18720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EI981_RS18725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EI981_RS18730	COG1845	cytochrome c oxidase, subunit III
EI981_RS18735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EI981_RS18745	COG0800	Aldolase
EI981_RS18750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EI981_RS18770	COG3708	Transcriptional regulator
EI981_RS18770	COG2207	Transcriptional regulator
EI981_RS18780	COG0523	cobalamin synthesis protein
EI981_RS18785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EI981_RS18790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EI981_RS18795	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EI981_RS18825	COG1846	Transcriptional regulator
EI981_RS18830	COG2814	Major facilitator Superfamily
EI981_RS18835	COG0656	L-ascorbic acid biosynthetic process
EI981_RS18840	COG2814	Major facilitator Superfamily
EI981_RS18845	COG1733	regulation of RNA biosynthetic process
EI981_RS18850	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS18860	COG1917	Cupin 2, conserved barrel domain protein
EI981_RS18860	COG4977	sequence-specific DNA binding
EI981_RS18870	COG0088	Forms part of the polypeptide exit tunnel
EI981_RS18885	COG2378	regulation of single-species biofilm formation
EI981_RS18895	COG4608	Belongs to the ABC transporter superfamily
EI981_RS18900	COG0444	Belongs to the ABC transporter superfamily
EI981_RS18905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI981_RS18915	COG0747	negative chemotaxis
EI981_RS18920	COG1234	tRNA 3'-trailer cleavage
EI981_RS18925	COG1737	Transcriptional regulator
EI981_RS18930	COG1011	Hydrolase
EI981_RS18965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EI981_RS18975	COG0745	RESPONSE REGULATOR receiver
EI981_RS19000	COG1501	Belongs to the glycosyl hydrolase 31 family
EI981_RS19010	COG0395	ABC-type sugar transport system, permease component
EI981_RS19015	COG1175	transmembrane transport
EI981_RS19025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS19025	COG2207	Transcriptional regulator
EI981_RS19035	COG3239	Fatty acid desaturase
EI981_RS19045	COG1278	Cold shock
EI981_RS19055	COG0281	malic enzyme
EI981_RS19070	COG5002	protein histidine kinase activity
EI981_RS19075	COG0745	RESPONSE REGULATOR receiver
EI981_RS19080	COG2814	Major facilitator Superfamily
EI981_RS19085	COG1309	transcriptional regulator
EI981_RS19105	COG1131	(ABC) transporter
EI981_RS19140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EI981_RS19150	COG0535	radical SAM domain protein
EI981_RS19155	COG0613	PHP domain protein
EI981_RS19160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI981_RS19170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EI981_RS19195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EI981_RS19200	COG3949	Membrane
EI981_RS19210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EI981_RS19210	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EI981_RS19220	COG0561	phosphatase activity
EI981_RS19225	COG1187	pseudouridine synthase activity
EI981_RS19230	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EI981_RS19230	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EI981_RS19235	COG1547	Domain of unknown function (DUF309)
EI981_RS19240	COG2357	RelA SpoT domain protein
EI981_RS19245	COG0167	dihydroorotate dehydrogenase activity
EI981_RS19250	COG1376	ErfK ybiS ycfS ynhG family protein
EI981_RS19255	COG1141	Ferredoxin
EI981_RS19260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EI981_RS19265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EI981_RS19280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI981_RS19285	COG0004	ammonium transporteR
EI981_RS19295	COG2738	Putative neutral zinc metallopeptidase
EI981_RS19300	COG0583	DNA-binding transcription factor activity
EI981_RS19305	COG0705	Rhomboid family
EI981_RS19310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EI981_RS19330	COG0513	Belongs to the DEAD box helicase family
EI981_RS19335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EI981_RS19345	COG0534	Mate efflux family protein
EI981_RS19365	COG1494	fructose-1,6-bisphosphatase
EI981_RS19370	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EI981_RS19375	COG0517	IMP dehydrogenase activity
EI981_RS19380	COG1609	Transcriptional regulator
EI981_RS19420	COG0395	ABC-type sugar transport system, permease component
EI981_RS19425	COG4209	transmembrane transport
EI981_RS19475	COG1164	Oligoendopeptidase f
EI981_RS19480	COG5416	Lipopolysaccharide assembly protein A domain
EI981_RS19485	COG1363	Peptidase, m42
EI981_RS19490	COG0488	(ABC) transporter
EI981_RS19505	COG0584	glycerophosphoryl diester phosphodiesterase
EI981_RS19510	COG2843	Capsule synthesis protein
EI981_RS19515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EI981_RS19520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EI981_RS19525	COG2814	Major facilitator Superfamily
EI981_RS19530	COG4122	O-methyltransferase activity
EI981_RS19535	COG0116	Belongs to the methyltransferase superfamily
EI981_RS19540	COG1368	sulfuric ester hydrolase activity
EI981_RS19545	COG0346	lactoylglutathione lyase activity
EI981_RS19550	COG4844	belongs to the
EI981_RS19580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EI981_RS19590	COG2445	Protein of unknown function DUF86
EI981_RS19615	COG1486	melibiose metabolic process
EI981_RS19620	COG2971	BadF BadG BcrA BcrD
EI981_RS19625	COG1917	Cupin 2, conserved barrel domain protein
EI981_RS19625	COG2207	Transcriptional regulator
EI981_RS19635	COG2848	UPF0210 protein
EI981_RS19640	COG3830	Belongs to the UPF0237 family
EI981_RS19645	COG0745	RESPONSE REGULATOR receiver
EI981_RS19670	COG5297	Belongs to the glycosyl hydrolase family 6
EI981_RS19670	COG4447	cellulose binding
EI981_RS19675	COG1309	transcriptional regulator
EI981_RS19680	COG1733	regulation of RNA biosynthetic process
EI981_RS19775	COG1335	isochorismatase
EI981_RS19780	COG3180	Ammonia monooxygenase
EI981_RS19785	COG1959	2 iron, 2 sulfur cluster binding
EI981_RS19790	COG0697	spore germination
EI981_RS19795	COG3397	chitin binding
EI981_RS19810	COG0586	Pfam SNARE associated Golgi protein
EI981_RS19825	COG0581	inorganic phosphate transmembrane transporter activity
EI981_RS19830	COG0573	inorganic phosphate transmembrane transporter activity
EI981_RS19835	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EI981_RS19845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EI981_RS19860	COG0237	dephospho-CoA kinase activity
EI981_RS19865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EI981_RS19875	COG0704	Plays a role in the regulation of phosphate uptake
EI981_RS19880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EI981_RS19885	COG0840	transmembrane signaling receptor activity
EI981_RS19890	COG0745	RESPONSE REGULATOR receiver
EI981_RS19895	COG5002	protein histidine kinase activity
EI981_RS19905	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EI981_RS19910	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS19920	COG0538	isocitrate dehydrogenase activity
EI981_RS19925	COG0372	Belongs to the citrate synthase family
EI981_RS19930	COG0628	permease
EI981_RS19935	COG0018	arginyl-trna synthetase
EI981_RS19940	COG3030	protein affecting phage T7 exclusion by the F plasmid
EI981_RS19945	COG0824	Thioesterase
EI981_RS19950	COG0469	pyruvate kinase activity
EI981_RS19955	COG0825	malonyl-CoA metabolic process
EI981_RS19960	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EI981_RS19970	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EI981_RS20000	COG4109	DRTGG domain
EI981_RS20010	COG1609	Transcriptional regulator
EI981_RS20015	COG0697	spore germination
EI981_RS20025	COG3250	beta-galactosidase activity
EI981_RS20030	COG0395	ABC-type sugar transport system, permease component
EI981_RS20035	COG1175	transmembrane transport
EI981_RS20050	COG3679	Belongs to the UPF0342 family
EI981_RS20055	COG4399	Belongs to the UPF0754 family
EI981_RS20060	COG0189	ligase activity
EI981_RS20065	COG0189	ligase activity
EI981_RS20070	COG0189	ligase activity
EI981_RS20085	COG0189	ligase activity
EI981_RS20105	COG5002	protein histidine kinase activity
EI981_RS20110	COG0745	RESPONSE REGULATOR receiver
EI981_RS20125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EI981_RS20125	COG2755	lipolytic protein G-D-S-L family
EI981_RS20145	COG2368	4-hydroxyphenylacetate
EI981_RS20165	COG1714	RDD family
EI981_RS20170	COG2318	DinB family
EI981_RS20195	COG0456	acetyltransferase
EI981_RS20245	COG0572	uridine kinase
EI981_RS20315	COG0745	RESPONSE REGULATOR receiver
EI981_RS20320	COG5002	protein histidine kinase activity
EI981_RS20330	COG0577	efflux transmembrane transporter activity
EI981_RS20335	COG1136	(ABC) transporter
EI981_RS20350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EI981_RS20370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EI981_RS20390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EI981_RS20515	COG0456	acetyltransferase
EI981_RS20515	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EI981_RS20520	COG0789	Transcriptional regulator
EI981_RS20525	COG1131	(ABC) transporter
EI981_RS20540	COG1254	Belongs to the acylphosphatase family
EI981_RS20570	COG2340	Cysteine-rich secretory protein family
EI981_RS20580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EI981_RS20650	COG0596	Alpha beta hydrolase
EI981_RS20660	COG4974	Belongs to the 'phage' integrase family
EI981_RS20665	COG3546	catalase activity
EI981_RS20685	COG1253	flavin adenine dinucleotide binding
EI981_RS20690	COG0535	radical SAM domain protein
EI981_RS20695	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EI981_RS20700	COG0737	Belongs to the 5'-nucleotidase family
EI981_RS20740	COG0719	Fe-S assembly protein
EI981_RS20745	COG0822	iron-sulfur transferase activity
EI981_RS20750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EI981_RS20755	COG0719	Fe-S assembly protein
EI981_RS20760	COG0396	ATPase activity
EI981_RS20770	COG2363	Small membrane protein
EI981_RS20780	COG1307	EDD domain protein, DegV family
EI981_RS20785	COG1307	EDD domain protein, DegV family
EI981_RS20790	COG2719	SpoVR family
EI981_RS20795	COG2718	Belongs to the UPF0229 family
EI981_RS20805	COG1940	carbohydrate kinase activity
EI981_RS20810	COG0363	glucosamine-6-phosphate deaminase activity
EI981_RS20815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EI981_RS20820	COG2766	serine protein kinase
EI981_RS20830	COG0436	Aminotransferase
EI981_RS20845	COG2002	toxin-antitoxin pair type II binding
EI981_RS20850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EI981_RS20865	COG2195	Cleaves the N-terminal amino acid of tripeptides
EI981_RS20875	COG0174	glutamine synthetase
EI981_RS20880	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EI981_RS20885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EI981_RS20890	COG5002	protein histidine kinase activity
EI981_RS20890	COG3850	Histidine kinase
EI981_RS20895	COG0745	RESPONSE REGULATOR receiver
EI981_RS20900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI981_RS20905	COG2197	response regulator
EI981_RS20910	COG4585	Histidine kinase
EI981_RS20915	COG4758	membrane
EI981_RS20920	COG3584	3D domain protein
EI981_RS20925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EI981_RS20935	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EI981_RS20940	COG0626	cystathionine gamma-synthase activity
EI981_RS20945	COG0626	cystathionine gamma-synthase activity
EI981_RS20950	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EI981_RS20955	COG0598	Magnesium transport protein CorA
EI981_RS20970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EI981_RS20975	COG1393	Belongs to the ArsC family
EI981_RS20980	COG0564	pseudouridine synthase activity
EI981_RS20985	COG2096	Adenosyltransferase
EI981_RS20995	COG0436	Aminotransferase
EI981_RS21000	COG1522	sequence-specific DNA binding
EI981_RS21015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI981_RS21025	COG1193	negative regulation of DNA recombination
EI981_RS21050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EI981_RS21095	COG4191	Histidine kinase
EI981_RS21100	COG0402	S-adenosylhomocysteine deaminase activity
EI981_RS21105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EI981_RS21115	COG0450	alkyl hydroperoxide reductase
EI981_RS21120	COG0473	3-isopropylmalate dehydrogenase activity
EI981_RS21125	COG2264	protein methyltransferase activity
EI981_RS21130	COG0371	Dehydrogenase
EI981_RS21135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EI981_RS21140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EI981_RS21145	COG0440	acetolactate synthase activity
EI981_RS21150	COG0028	Belongs to the TPP enzyme family
EI981_RS21165	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EI981_RS21170	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EI981_RS21180	COG1215	transferase activity, transferring glycosyl groups
EI981_RS21185	COG0671	phosphoesterase, PA-phosphatase related
EI981_RS21190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EI981_RS21195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EI981_RS21200	COG1242	4 iron, 4 sulfur cluster binding
EI981_RS21220	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EI981_RS21235	COG0514	ATP-dependent DNA helicase (RecQ)
EI981_RS21240	COG0477	Major facilitator Superfamily
EI981_RS21245	COG1309	transcriptional regulator
EI981_RS21255	COG2207	Transcriptional regulator
EI981_RS21300	COG2814	Major facilitator Superfamily
EI981_RS21315	COG1120	ATPase activity
EI981_RS21320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI981_RS21325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI981_RS21330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS21335	COG1136	(ABC) transporter
EI981_RS21345	COG1357	PFAM Pentapeptide repeats (8 copies)
EI981_RS21375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EI981_RS21380	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EI981_RS21385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI981_RS21395	COG1970	mechanosensitive ion channel activity
EI981_RS21400	COG0840	transmembrane signaling receptor activity
EI981_RS21405	COG0640	Transcriptional regulator
EI981_RS21415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EI981_RS21420	COG0720	synthase
EI981_RS21430	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EI981_RS21435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EI981_RS21440	COG2814	Major facilitator Superfamily
EI981_RS21450	COG0006	proline dipeptidase activity
EI981_RS21455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EI981_RS21460	COG0840	transmembrane signaling receptor activity
EI981_RS21465	COG1509	lysine 2,3-aminomutase activity
EI981_RS21470	COG1492	cobalamin metabolic process
EI981_RS21475	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EI981_RS21485	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EI981_RS21490	COG1120	ATPase activity
EI981_RS21495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI981_RS21500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS21515	COG1309	transcriptional regulator
EI981_RS21550	COG2169	Transcriptional regulator
EI981_RS21555	COG0395	ABC-type sugar transport system, permease component
EI981_RS21560	COG4209	transmembrane transport
EI981_RS21575	COG1473	amidohydrolase
EI981_RS21580	COG1760	l-serine dehydratase
EI981_RS21585	COG1760	l-serine dehydratase
EI981_RS21610	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EI981_RS21620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EI981_RS21625	COG0095	Lipoate-protein ligase
EI981_RS21635	COG1131	(ABC) transporter
EI981_RS21640	COG0561	phosphatase activity
EI981_RS21645	COG0321	lipoyl(octanoyl) transferase activity
EI981_RS21645	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EI981_RS21650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EI981_RS21665	COG0432	Pfam Uncharacterised protein family UPF0047
EI981_RS21670	COG1309	transcriptional regulator
EI981_RS21675	COG1739	Uncharacterized protein family UPF0029
EI981_RS21680	COG0166	Belongs to the GPI family
EI981_RS21705	COG1653	transport
EI981_RS21710	COG0395	ABC-type sugar transport system, permease component
EI981_RS21715	COG4209	transmembrane transport
EI981_RS21730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EI981_RS21740	COG2731	YhcH YjgK YiaL family protein
EI981_RS21750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EI981_RS21795	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EI981_RS21805	COG3123	guanosine phosphorylase activity
EI981_RS21815	COG2304	oxidoreductase activity
EI981_RS21830	COG0714	Associated with various cellular activities
EI981_RS21845	COG1131	(ABC) transporter
EI981_RS21855	COG0788	formyltetrahydrofolate deformylase activity
EI981_RS21885	COG1090	epimerase
EI981_RS21940	COG3011	Protein conserved in bacteria
EI981_RS21965	COG2819	hydrolase of the alpha beta superfamily
EI981_RS21970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI981_RS21975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI981_RS21980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS21985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS21985	COG2207	Transcriptional regulator
EI981_RS22025	COG3091	SprT-like family
EI981_RS22040	COG2183	response to ionizing radiation
EI981_RS22050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI981_RS22050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI981_RS22055	COG1136	(ABC) transporter
EI981_RS22060	COG0577	efflux transmembrane transporter activity
EI981_RS22065	COG2337	Toxic component of a toxin-antitoxin (TA) module
EI981_RS22070	COG0864	Transcriptional regulator
EI981_RS22075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EI981_RS22080	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EI981_RS22085	COG0180	Tryptophanyl-tRNA synthetase
EI981_RS22090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EI981_RS22100	COG2211	Major facilitator Superfamily
EI981_RS22105	COG2972	Histidine kinase
EI981_RS22110	COG2207	Transcriptional regulator
EI981_RS22110	COG4753	response regulator
EI981_RS22120	COG0395	ABC-type sugar transport system, permease component
EI981_RS22125	COG4209	transmembrane transport
EI981_RS22130	COG1113	amino acid transport
EI981_RS22140	COG1510	regulation of RNA biosynthetic process
EI981_RS22145	COG4175	Glycine betaine
EI981_RS22145	COG0517	IMP dehydrogenase activity
EI981_RS22155	COG2113	Glycine betaine
EI981_RS22180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EI981_RS22190	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS22200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI981_RS22210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI981_RS22220	COG0583	DNA-binding transcription factor activity
EI981_RS22225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EI981_RS22230	COG0789	Transcriptional regulator
EI981_RS22230	COG4978	Transcriptional regulator
EI981_RS22235	COG2814	Major facilitator Superfamily
EI981_RS22240	COG0459	protein refolding
EI981_RS22245	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EI981_RS22255	COG5002	protein histidine kinase activity
EI981_RS22270	COG1760	l-serine dehydratase
EI981_RS22275	COG1760	l-serine dehydratase
EI981_RS22280	COG3481	metal-dependent phosphohydrolase, HD sub domain
EI981_RS22295	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EI981_RS22305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EI981_RS22315	COG3711	transcriptional antiterminator
EI981_RS22320	COG2268	Band 7 protein
EI981_RS22330	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EI981_RS22335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EI981_RS22340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EI981_RS22355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EI981_RS22360	COG0546	phosphoglycolate phosphatase activity
EI981_RS22365	COG3594	Acyltransferase
EI981_RS22380	COG0768	penicillin binding
EI981_RS22390	COG0826	peptidase U32
EI981_RS22395	COG0826	peptidase U32
EI981_RS22400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EI981_RS22405	COG3906	Belongs to the UPF0473 family
EI981_RS22430	COG0628	permease
EI981_RS22445	COG1104	cysteine desulfurase activity
EI981_RS22450	COG1959	2 iron, 2 sulfur cluster binding
EI981_RS22455	COG0482	sulfurtransferase activity
EI981_RS22460	COG1649	PFAM Uncharacterised BCR, COG1649
EI981_RS22460	COG0726	polysaccharide deacetylase
EI981_RS22465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EI981_RS22470	COG5566	PFAM Mor transcription activator
EI981_RS22475	COG3973	AAA domain
EI981_RS22480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EI981_RS22485	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EI981_RS22490	COG0124	histidyl-tRNA synthetase
EI981_RS22500	COG1490	D-aminoacyl-tRNA deacylase activity
EI981_RS22505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EI981_RS22520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EI981_RS22525	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EI981_RS22525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EI981_RS22535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EI981_RS22540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EI981_RS22540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EI981_RS22550	COG2244	polysaccharide biosynthetic process
EI981_RS22560	COG1862	Preprotein translocase
EI981_RS22565	COG0343	queuine tRNA-ribosyltransferase activity
EI981_RS22570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EI981_RS22575	COG2385	sporulation resulting in formation of a cellular spore
EI981_RS22575	COG2385	sporulation resulting in formation of a cellular spore
EI981_RS22580	COG2255	four-way junction helicase activity
EI981_RS22585	COG0632	four-way junction helicase activity
EI981_RS22590	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EI981_RS22610	COG0601	transmembrane transport
EI981_RS22615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI981_RS22620	COG0747	negative chemotaxis
EI981_RS22640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI981_RS22650	COG0395	ABC-type sugar transport system, permease component
EI981_RS22655	COG1175	transmembrane transport
EI981_RS22665	COG1554	hydrolase, family 65, central catalytic
EI981_RS22670	COG1609	Transcriptional regulator
EI981_RS22675	COG3458	cephalosporin-C deacetylase activity
EI981_RS22680	COG0395	ABC-type sugar transport system, permease component
EI981_RS22685	COG1175	transmembrane transport
EI981_RS22690	COG1653	transport
EI981_RS22695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS22695	COG2207	Transcriptional regulator
EI981_RS22700	COG2172	sigma factor antagonist activity
EI981_RS22710	COG3118	belongs to the thioredoxin family
EI981_RS22725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI981_RS22730	COG1917	Cupin 2, conserved barrel domain protein
EI981_RS22730	COG2207	Transcriptional regulator
EI981_RS22745	COG0395	ABC-type sugar transport system, permease component
EI981_RS22750	COG4209	transmembrane transport
EI981_RS22770	COG3458	cephalosporin-C deacetylase activity
EI981_RS22775	COG3275	phosphorelay sensor kinase activity
EI981_RS22780	COG2207	Transcriptional regulator
EI981_RS22780	COG4753	response regulator
EI981_RS22800	COG0395	ABC-type sugar transport system, permease component
EI981_RS22805	COG1175	transmembrane transport
EI981_RS22820	COG3833	ABC-type maltose transport systems, permease component
EI981_RS22825	COG1175	transmembrane transport
EI981_RS22850	COG4753	response regulator
EI981_RS22850	COG2207	Transcriptional regulator
EI981_RS22855	COG2972	Histidine kinase
EI981_RS22860	COG0395	ABC-type sugar transport system, permease component
EI981_RS22865	COG4209	transmembrane transport
EI981_RS22890	COG1609	Transcriptional regulator
EI981_RS22910	COG0395	ABC-type sugar transport system, permease component
EI981_RS22915	COG1175	transmembrane transport
EI981_RS22925	COG1595	DNA-templated transcription, initiation
EI981_RS22935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI981_RS23000	COG1388	LysM domain
EI981_RS23000	COG0791	NLP P60 protein
EI981_RS23010	COG0077	Prephenate dehydratase
EI981_RS23015	COG0083	homoserine kinase activity
EI981_RS23020	COG0460	homoserine dehydrogenase
EI981_RS23025	COG4492	Belongs to the UPF0735 family
EI981_RS23030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EI981_RS23040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EI981_RS23045	COG2868	ribosomal protein
EI981_RS23050	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EI981_RS23055	COG1349	DNA-binding transcription factor activity
EI981_RS23070	COG1530	ribonuclease E activity
EI981_RS23075	COG1994	Peptidase M50
EI981_RS23085	COG2894	cell division
EI981_RS23090	COG0850	regulation of cytokinetic process
EI981_RS23100	COG1792	Involved in formation and maintenance of cell shape
EI981_RS23105	COG1077	Cell shape determining protein MreB Mrl
EI981_RS23110	COG2003	Belongs to the UPF0758 family
EI981_RS23115	COG0424	maF-like protein
EI981_RS23125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EI981_RS23130	COG0285	dihydrofolate synthase activity
EI981_RS23135	COG0525	valine-tRNA ligase activity
EI981_RS23140	COG1388	LysM domain
EI981_RS23145	COG0564	pseudouridine synthase activity
EI981_RS23150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EI981_RS23155	COG0113	porphobilinogen synthase activity
EI981_RS23170	COG1648	precorrin-2 dehydrogenase activity
EI981_RS23170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EI981_RS23180	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EI981_RS23190	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EI981_RS23200	COG1067	ATP-dependent peptidase activity
EI981_RS23200	COG0470	DNA polymerase III
EI981_RS23210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EI981_RS23215	COG0740	serine-type endopeptidase activity
EI981_RS23220	COG0544	peptidyl-prolyl cis-trans isomerase activity
EI981_RS23235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EI981_RS23250	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS23255	COG2972	Histidine kinase
EI981_RS23260	COG2207	Transcriptional regulator
EI981_RS23260	COG4753	response regulator
EI981_RS23265	COG1653	transport
EI981_RS23270	COG0395	ABC-type sugar transport system, permease component
EI981_RS23275	COG4209	transmembrane transport
EI981_RS23285	COG0745	RESPONSE REGULATOR receiver
EI981_RS23290	COG2132	Multicopper oxidase
EI981_RS23315	COG0386	Belongs to the glutathione peroxidase family
EI981_RS23330	COG1940	carbohydrate kinase activity
EI981_RS23335	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EI981_RS23355	COG0367	asparagine synthase
EI981_RS23370	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EI981_RS23375	COG5401	PFAM Sporulation and spore germination
EI981_RS23380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EI981_RS23400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EI981_RS23405	COG2197	response regulator
EI981_RS23410	COG2822	iron ion transport
EI981_RS23415	COG2837	iron assimilation
EI981_RS23420	COG0672	)-iron permease
EI981_RS23425	COG1846	Transcriptional regulator
EI981_RS23435	COG0363	glucosamine-6-phosphate deaminase activity
EI981_RS23440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EI981_RS23450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI981_RS23460	COG4641	Protein conserved in bacteria
EI981_RS23500	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EI981_RS23505	COG1216	Glycosyl transferase, family 2
EI981_RS23520	COG0438	transferase activity, transferring glycosyl groups
EI981_RS23530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EI981_RS23535	COG1122	ATPase activity
EI981_RS23540	COG4721	ABC-type cobalt transport system, permease component
EI981_RS23545	COG0688	phosphatidylethanolamine metabolic process
EI981_RS23565	COG1131	(ABC) transporter
EI981_RS23575	COG0300	oxidoreductase activity
EI981_RS23585	COG0583	DNA-binding transcription factor activity
EI981_RS23590	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EI981_RS23610	COG3695	enzyme binding
EI981_RS23615	COG1472	Belongs to the glycosyl hydrolase 3 family
EI981_RS23620	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EI981_RS23625	COG0709	Synthesizes selenophosphate from selenide and ATP
EI981_RS23630	COG2832	Protein of unknown function (DUF454)
EI981_RS23635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EI981_RS23640	COG1053	succinate dehydrogenase
EI981_RS23645	COG2009	succinate dehydrogenase
EI981_RS23650	COG0583	DNA-binding transcription factor activity
EI981_RS23660	COG0569	domain protein
EI981_RS23665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EI981_RS23675	COG0322	excinuclease ABC activity
EI981_RS23680	COG3118	belongs to the thioredoxin family
EI981_RS23690	COG1484	DNA-dependent DNA replication
EI981_RS23715	COG1252	NADH dehydrogenase
EI981_RS23720	COG0492	ferredoxin-NADP+ reductase activity
EI981_RS23735	COG0189	ligase activity
EI981_RS23745	COG0628	permease
EI981_RS23750	COG0316	Belongs to the HesB IscA family
EI981_RS23755	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EI981_RS23760	COG4844	belongs to the
EI981_RS23765	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EI981_RS23770	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS23775	COG2972	Histidine kinase
EI981_RS23795	COG1175	transmembrane transport
EI981_RS23800	COG0395	ABC-type sugar transport system, permease component
EI981_RS23810	COG5426	von Willebrand factor, type A
EI981_RS23820	COG2011	ABC-type metal ion transport system permease component
EI981_RS23825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EI981_RS23845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI981_RS23855	COG2244	polysaccharide biosynthetic process
EI981_RS23860	COG2839	Protein conserved in bacteria
EI981_RS23865	COG0561	phosphatase activity
EI981_RS23870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EI981_RS23875	COG1321	iron dependent repressor
EI981_RS23875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EI981_RS23880	COG1121	(ABC) transporter
EI981_RS23885	COG0803	Belongs to the bacterial solute-binding protein 9 family
EI981_RS23920	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EI981_RS23930	COG0109	protoheme IX farnesyltransferase activity
EI981_RS23935	COG0180	Tryptophanyl-tRNA synthetase
EI981_RS23960	COG3093	addiction module antidote protein HigA
EI981_RS23975	COG2346	COG2346, Truncated hemoglobins
EI981_RS23980	COG3314	Sporulation integral membrane protein YlbJ
EI981_RS23990	COG0793	Belongs to the peptidase S41A family
EI981_RS23990	COG3409	Peptidoglycan-binding domain 1 protein
EI981_RS23995	COG4470	Protein conserved in bacteria
EI981_RS24000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EI981_RS24005	COG0739	heme binding
EI981_RS24015	COG1477	protein flavinylation
EI981_RS24020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI981_RS24025	COG0569	domain protein
EI981_RS24035	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EI981_RS24040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EI981_RS24050	COG2197	response regulator
EI981_RS24055	COG4585	Histidine kinase
EI981_RS24065	COG1842	Phage shock protein A
EI981_RS24075	COG1842	Phage shock protein A
EI981_RS24090	COG0490	domain, Protein
EI981_RS24100	COG0602	queuosine metabolic process
EI981_RS24120	COG1694	Mazg nucleotide pyrophosphohydrolase
EI981_RS24250	COG3858	chitin binding
EI981_RS24255	COG0735	belongs to the Fur family
EI981_RS24270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EI981_RS24275	COG0154	amidase activity
EI981_RS24280	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EI981_RS24290	COG1285	pathogenesis
EI981_RS24295	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EI981_RS24300	COG1131	(ABC) transporter
EI981_RS24320	COG1595	DNA-templated transcription, initiation
EI981_RS24330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI981_RS24340	COG0586	Pfam SNARE associated Golgi protein
EI981_RS24365	COG2267	carboxylic ester hydrolase activity
EI981_RS24395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EI981_RS24405	COG0488	(ABC) transporter
EI981_RS24415	COG1294	oxidase, subunit
EI981_RS24420	COG1271	oxidase subunit
EI981_RS24425	COG0737	Belongs to the 5'-nucleotidase family
EI981_RS24430	COG1079	Belongs to the binding-protein-dependent transport system permease family
EI981_RS24435	COG4603	Belongs to the binding-protein-dependent transport system permease family
EI981_RS24440	COG3845	ABC transporter
EI981_RS24445	COG1744	ABC transporter substrate-binding protein PnrA-like
EI981_RS24450	COG1413	lyase activity
EI981_RS24455	COG0833	amino acid
EI981_RS24475	COG2217	Heavy metal translocating P-type atpase
EI981_RS24490	COG1131	(ABC) transporter
EI981_RS24515	COG1131	(ABC) transporter
EI981_RS24520	COG0242	peptide deformylase activity
EI981_RS24530	COG1309	transcriptional regulator
EI981_RS24535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI981_RS24550	COG1227	inorganic diphosphatase activity
EI981_RS24555	COG0745	RESPONSE REGULATOR receiver
EI981_RS24560	COG5002	protein histidine kinase activity
EI981_RS24565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EI981_RS24575	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS24580	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EI981_RS24595	COG1937	Protein conserved in bacteria
EI981_RS24605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI981_RS24615	COG2210	Belongs to the sulfur carrier protein TusA family
EI981_RS24620	COG1104	cysteine desulfurase activity
EI981_RS24630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EI981_RS24635	COG1846	Transcriptional regulator
EI981_RS24640	COG2814	Major facilitator Superfamily
EI981_RS24645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EI981_RS24670	COG0366	Alpha amylase catalytic
EI981_RS24675	COG0395	ABC-type sugar transport system, permease component
EI981_RS24680	COG1175	transmembrane transport
EI981_RS24705	COG1136	(ABC) transporter
EI981_RS24705	COG0577	efflux transmembrane transporter activity
EI981_RS24710	COG5002	protein histidine kinase activity
EI981_RS24715	COG0745	RESPONSE REGULATOR receiver
EI981_RS24730	COG0395	ABC-type sugar transport system, permease component
EI981_RS24735	COG4209	transmembrane transport
EI981_RS24740	COG1653	transport
EI981_RS24750	COG2972	Histidine kinase
EI981_RS24760	COG3275	phosphorelay sensor kinase activity
EI981_RS24765	COG1653	transport
EI981_RS24770	COG0395	ABC-type sugar transport system, permease component
EI981_RS24775	COG4209	transmembrane transport
EI981_RS24805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI981_RS24815	COG2315	Protein conserved in bacteria
EI981_RS24820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI981_RS24825	COG0456	acetyltransferase
EI981_RS24830	COG4977	sequence-specific DNA binding
EI981_RS24830	COG1917	Cupin 2, conserved barrel domain protein
EI981_RS24835	COG0673	inositol 2-dehydrogenase activity
EI981_RS24840	COG0577	efflux transmembrane transporter activity
EI981_RS24845	COG1136	(ABC) transporter
EI981_RS24850	COG2205	protein histidine kinase activity
EI981_RS24855	COG0745	RESPONSE REGULATOR receiver
EI981_RS24860	COG0716	FMN binding
EI981_RS24865	COG0444	Belongs to the ABC transporter superfamily
EI981_RS24870	COG0488	(ABC) transporter
EI981_RS24880	COG3833	ABC-type maltose transport systems, permease component
EI981_RS24885	COG1175	transmembrane transport
EI981_RS24895	COG3437	response regulator, receiver
EI981_RS24900	COG0596	Alpha beta hydrolase
EI981_RS24905	COG2197	response regulator
EI981_RS24910	COG4585	Histidine kinase
EI981_RS24915	COG1151	hydroxylamine reductase activity
EI981_RS24930	COG1309	transcriptional regulator
EI981_RS24955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EI981_RS24960	COG4856	YbbR-like protein
EI981_RS24965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EI981_RS24970	COG5662	AntiSigma factor
EI981_RS24975	COG1595	DNA-templated transcription, initiation
EI981_RS24980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EI981_RS25065	COG0726	polysaccharide deacetylase
EI981_RS25070	COG2194	sulfuric ester hydrolase activity
EI981_RS25080	COG0489	protein tyrosine kinase activity
EI981_RS25085	COG0860	N-Acetylmuramoyl-L-alanine amidase
EI981_RS25090	COG2046	Belongs to the sulfate adenylyltransferase family
EI981_RS25095	COG0175	sulfate reduction
EI981_RS25135	COG4824	toxin secretion phage lysis holin
EI981_RS25260	COG0582	viral genome integration into host DNA
EI981_RS25330	COG0582	viral genome integration into host DNA
EI981_RS25335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EI981_RS25340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EI981_RS25350	COG0101	tRNA pseudouridine synthase activity
EI981_RS25355	COG0203	ribosomal protein L17
EI981_RS25360	COG0202	RNA polymerase activity
EI981_RS25365	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EI981_RS25370	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EI981_RS25375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EI981_RS25380	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EI981_RS25385	COG2163	COG2163 Ribosomal protein L14E L6E L27E
EI981_RS25390	COG0024	Methionine aminopeptidase
EI981_RS25395	COG0563	adenylate kinase activity
EI981_RS25400	COG0201	protein transport
EI981_RS25405	COG0200	Binds to the 23S rRNA
EI981_RS25410	COG1841	ribosomal large subunit assembly
EI981_RS25415	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EI981_RS25420	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EI981_RS25425	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EI981_RS25430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EI981_RS25435	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EI981_RS25440	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EI981_RS25445	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EI981_RS25450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EI981_RS25455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EI981_RS25460	COG0255	Belongs to the universal ribosomal protein uL29 family
EI981_RS25465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EI981_RS25470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EI981_RS25475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EI981_RS25480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EI981_RS25485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EI981_RS25490	COG0089	rRNA binding
EI981_RS25495	COG0088	Forms part of the polypeptide exit tunnel
EI981_RS25500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EI981_RS25510	COG0840	transmembrane signaling receptor activity
EI981_RS25515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EI981_RS25525	COG0049	tRNA binding
EI981_RS25530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EI981_RS25535	COG1358	cellular component organization or biogenesis
EI981_RS25540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EI981_RS25545	COG0085	RNA polymerase activity
EI981_RS25550	COG2813	Specifically methylates the guanine in position
EI981_RS25555	COG0222	ribosome binding
EI981_RS25560	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EI981_RS25565	COG0081	regulation of translation
EI981_RS25575	COG0250	Participates in transcription elongation, termination and antitermination
EI981_RS25580	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EI981_RS25585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EI981_RS25595	COG3688	RNA-binding protein containing a PIN domain
EI981_RS25600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI981_RS25605	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EI981_RS25610	COG0215	cysteine-tRNA ligase activity
EI981_RS25615	COG1045	serine acetyltransferase
EI981_RS25620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI981_RS25625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EI981_RS25630	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EI981_RS25635	COG4956	integral membrane protein (PIN domain superfamily)
EI981_RS25645	COG1183	phosphatidylcholine synthase activity
EI981_RS25650	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EI981_RS25655	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EI981_RS25660	COG0542	response to heat
EI981_RS25665	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EI981_RS25670	COG3880	PFAM UvrB UvrC protein
EI981_RS25680	COG4753	response regulator
EI981_RS25680	COG2207	Transcriptional regulator
EI981_RS25685	COG2972	Histidine kinase
EI981_RS25695	COG4214	carbohydrate transport
EI981_RS25705	COG4213	ABC transporter substrate-binding protein
EI981_RS25735	COG1653	transport
EI981_RS25745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EI981_RS25750	COG0210	DNA helicase
EI981_RS25755	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EI981_RS25785	COG1091	dTDP-4-dehydrorhamnose reductase activity
EI981_RS25800	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EI981_RS25805	COG0463	Glycosyl transferase, family 2
EI981_RS25820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EI981_RS25865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI981_RS25870	COG0110	maltose O-acetyltransferase activity
EI981_RS25885	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EI981_RS25885	COG0662	Cupin 2, conserved barrel domain protein
EI981_RS25900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EI981_RS25915	COG2391	methyltransferase activity
EI981_RS25920	COG0425	Belongs to the sulfur carrier protein TusA family
EI981_RS25920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EI981_RS25925	COG2391	methyltransferase activity
EI981_RS25930	COG0583	DNA-binding transcription factor activity
EI981_RS25940	COG0826	peptidase U32
EI981_RS25945	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EI981_RS25945	COG4447	cellulose binding
EI981_RS25955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EI981_RS25960	COG0556	nucleotide-excision repair
EI981_RS25965	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EI981_RS25970	COG1360	Flagellar Motor Protein
EI981_RS25975	COG4667	esterase of the alpha-beta hydrolase superfamily
EI981_RS25980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI981_RS25985	COG0793	Belongs to the peptidase S41A family
EI981_RS25985	COG3409	Peptidoglycan-binding domain 1 protein
EI981_RS25990	COG0739	heme binding
EI981_RS25995	COG2177	Part of the ABC transporter FtsEX involved in
EI981_RS26000	COG2884	Cell division ATP-binding protein ftsE
EI981_RS26005	COG2720	vancomycin resistance protein
EI981_RS26020	COG2971	BadF BadG BcrA BcrD
EI981_RS26025	COG3876	Protein conserved in bacteria
EI981_RS26040	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EI981_RS26045	COG0395	ABC-type sugar transport system, permease component
EI981_RS26050	COG1175	transmembrane transport
EI981_RS26060	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EI981_RS26070	COG1737	Transcriptional regulator
EI981_RS26075	COG1486	melibiose metabolic process
EI981_RS26105	COG2807	transmembrane transport
EI981_RS26110	COG1664	Polymer-forming cytoskeletal
EI981_RS26115	COG1664	Polymer-forming cytoskeletal
EI981_RS26120	COG0789	Transcriptional regulator
EI981_RS26130	COG0165	Argininosuccinate lyase
EI981_RS26135	COG0137	argininosuccinate synthase activity
EI981_RS26140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EI981_RS26150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EI981_RS26155	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EI981_RS26160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EI981_RS26170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS26175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EI981_RS26185	COG0653	protein targeting
EI981_RS26195	COG1278	Cold shock
EI981_RS26205	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EI981_RS26210	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS26225	COG2089	acid synthase
EI981_RS26235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI981_RS26240	COG1086	Polysaccharide biosynthesis protein
EI981_RS26255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EI981_RS26265	COG1516	flagellar protein fliS
EI981_RS26270	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EI981_RS26280	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EI981_RS26295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EI981_RS26300	COG1256	bacterial-type flagellum assembly
EI981_RS26300	COG4786	Flagellar basal body rod
EI981_RS26325	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EI981_RS26360	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EI981_RS26400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EI981_RS26420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EI981_RS26425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EI981_RS26440	COG4786	Flagellar basal body rod
EI981_RS26450	COG1609	Transcriptional regulator
EI981_RS26455	COG0739	heme binding
EI981_RS26460	COG2385	sporulation resulting in formation of a cellular spore
EI981_RS26465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EI981_RS26475	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI981_RS26485	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EI981_RS26490	COG4869	propanediol catabolic process
EI981_RS26530	COG0235	Class ii aldolase
EI981_RS26535	COG1349	DNA-binding transcription factor activity
EI981_RS26540	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EI981_RS26550	COG1172	Belongs to the binding-protein-dependent transport system permease family
EI981_RS26555	COG1129	ABC transporter
EI981_RS26565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EI981_RS26570	COG4836	Membrane
EI981_RS26580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EI981_RS26585	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EI981_RS26590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EI981_RS26595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EI981_RS26605	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EI981_RS26610	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EI981_RS26630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EI981_RS26635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EI981_RS26640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EI981_RS26645	COG4475	Protein of unknown function (DUF436)
EI981_RS26655	COG1971	Probably functions as a manganese efflux pump
EI981_RS26665	COG1801	Protein of unknown function DUF72
EI981_RS26670	COG0009	L-threonylcarbamoyladenylate synthase
EI981_RS26680	COG0772	Belongs to the SEDS family
EI981_RS26685	COG2890	protein-(glutamine-N5) methyltransferase activity
EI981_RS26690	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EI981_RS26705	COG0012	GTP binding
EI981_RS26710	COG1304	FMN binding
EI981_RS26715	COG1233	COG1233 Phytoene dehydrogenase and related
EI981_RS26720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EI981_RS26725	COG1309	transcriptional regulator
EI981_RS26730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI981_RS26735	COG2801	Transposase and inactivated derivatives
EI981_RS26745	COG0746	molybdenum cofactor guanylyltransferase activity
EI981_RS26755	COG1609	Transcriptional regulator
EI981_RS26760	COG0475	glutathione-regulated potassium exporter activity
EI981_RS26765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI981_RS26770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EI981_RS26775	COG2814	Major facilitator Superfamily
EI981_RS26780	COG0243	molybdopterin cofactor binding
EI981_RS26785	COG2116	formate transmembrane transporter activity
EI981_RS26795	COG1120	ATPase activity
EI981_RS26800	COG1876	peptidase activity
EI981_RS26805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EI981_RS26815	COG1587	Uroporphyrinogen-III synthase
EI981_RS26820	COG0531	amino acid
EI981_RS26830	COG0697	spore germination
EI981_RS26840	COG0745	RESPONSE REGULATOR receiver
EI981_RS26850	COG0723	plastoquinol--plastocyanin reductase activity
EI981_RS26850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI981_RS26870	COG1914	H( )-stimulated, divalent metal cation uptake system
EI981_RS26880	COG1216	Glycosyl transferase, family 2
EI981_RS26890	COG2076	Multidrug Resistance protein
EI981_RS26900	COG2972	Histidine kinase
EI981_RS26905	COG4753	response regulator
EI981_RS26905	COG2207	Transcriptional regulator
EI981_RS26910	COG1653	transport
EI981_RS26915	COG1175	transmembrane transport
EI981_RS26935	COG1846	Transcriptional regulator
EI981_RS26945	COG0531	amino acid
EI981_RS26950	COG0583	DNA-binding transcription factor activity
EI981_RS26955	COG1380	Effector of murein hydrolase LrgA
EI981_RS26960	COG1346	cytolysis
EI981_RS26965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EI981_RS26970	COG1252	NADH dehydrogenase
EI981_RS26980	COG0583	DNA-binding transcription factor activity
EI981_RS26990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EI981_RS26995	COG4988	ABC transporter
EI981_RS27000	COG1294	oxidase, subunit
EI981_RS27005	COG1271	oxidase subunit
EI981_RS27015	COG1131	(ABC) transporter
EI981_RS27020	COG0753	catalase activity
EI981_RS27070	COG1575	Belongs to the MenA family. Type 1 subfamily
EI981_RS27090	COG1316	TRANSCRIPTIONal
EI981_RS27100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EI981_RS27105	COG0438	transferase activity, transferring glycosyl groups
EI981_RS27145	COG0673	inositol 2-dehydrogenase activity
EI981_RS27160	COG0438	transferase activity, transferring glycosyl groups
EI981_RS27170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI981_RS27190	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS27200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EI981_RS27205	COG1028	Short-chain dehydrogenase reductase Sdr
EI981_RS27210	COG0395	ABC-type sugar transport system, permease component
EI981_RS27215	COG4209	transmembrane transport
EI981_RS27225	COG4753	response regulator
EI981_RS27225	COG2207	Transcriptional regulator
EI981_RS27230	COG3275	phosphorelay sensor kinase activity
EI981_RS27245	COG0400	carboxylic ester hydrolase activity
EI981_RS27250	COG0346	lactoylglutathione lyase activity
EI981_RS27255	COG2259	Doxx family
EI981_RS27260	COG1846	Transcriptional regulator
EI981_RS27270	COG2814	Major facilitator Superfamily
EI981_RS27280	COG1136	(ABC) transporter
EI981_RS27285	COG2205	protein histidine kinase activity
EI981_RS27295	COG0737	Belongs to the 5'-nucleotidase family
EI981_RS27310	COG3639	organic phosphonate transmembrane transporter activity
EI981_RS27320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI981_RS27325	COG2146	nitrite reductase [NAD(P)H] activity
EI981_RS27330	COG2116	formate transmembrane transporter activity
EI981_RS27335	COG1609	Transcriptional regulator
EI981_RS27340	COG3459	Glycosyltransferase 36 associated
EI981_RS27350	COG0395	ABC-type sugar transport system, permease component
EI981_RS27355	COG4209	transmembrane transport
EI981_RS27385	COG2207	Transcriptional regulator
EI981_RS27385	COG0662	Cupin 2, conserved barrel domain protein
EI981_RS27390	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EI981_RS27400	COG1361	Conserved repeat domain
EI981_RS27420	COG3069	C4-dicarboxylate transmembrane transporter activity
EI981_RS27425	COG0667	Aldo Keto reductase
EI981_RS27430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI981_RS27435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI981_RS27440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI981_RS27450	COG4935	Belongs to the peptidase S8 family
EI981_RS27450	COG2234	aminopeptidase activity
EI981_RS27475	COG0745	RESPONSE REGULATOR receiver
EI981_RS27480	COG0642	Histidine kinase
EI981_RS27485	COG1136	(ABC) transporter
EI981_RS27490	COG0577	efflux transmembrane transporter activity
EI981_RS27505	COG2249	NAD(P)H dehydrogenase (quinone) activity
EI981_RS27525	COG2972	Histidine kinase
EI981_RS27530	COG2207	Transcriptional regulator
EI981_RS27540	COG1175	transmembrane transport
EI981_RS27550	COG2211	Major facilitator Superfamily
EI981_RS27560	COG5002	protein histidine kinase activity
EI981_RS27590	COG1696	Membrane protein involved in D-alanine export
EI981_RS27600	COG2972	Histidine kinase
EI981_RS27600	COG0745	RESPONSE REGULATOR receiver
EI981_RS27620	COG0492	ferredoxin-NADP+ reductase activity
EI981_RS27625	COG2207	Transcriptional regulator
EI981_RS27630	COG1653	transport
EI981_RS27635	COG0395	ABC-type sugar transport system, permease component
EI981_RS27640	COG4209	transmembrane transport
EI981_RS27650	COG4122	O-methyltransferase activity
EI981_RS27655	COG0583	DNA-binding transcription factor activity
EI981_RS27660	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EI981_RS27685	COG1131	(ABC) transporter
EI981_RS27690	COG2205	protein histidine kinase activity
EI981_RS27695	COG0745	RESPONSE REGULATOR receiver
EI981_RS27700	COG0510	thiamine kinase activity
EI981_RS27705	COG2807	transmembrane transport
EI981_RS27730	COG0395	ABC-type sugar transport system, permease component
EI981_RS27735	COG4209	transmembrane transport
EI981_RS27740	COG4753	response regulator
EI981_RS27740	COG2207	Transcriptional regulator
EI981_RS27750	COG3250	beta-galactosidase activity
EI981_RS27760	COG0395	ABC-type sugar transport system, permease component
EI981_RS27765	COG1175	transmembrane transport
EI981_RS27785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI981_RS27790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EI981_RS27800	COG0579	oxidoreductase
EI981_RS27805	COG0581	inorganic phosphate transmembrane transporter activity
EI981_RS27810	COG0573	inorganic phosphate transmembrane transporter activity
EI981_RS27815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EI981_RS27825	COG0456	acetyltransferase
EI981_RS27825	COG0454	-acetyltransferase
EI981_RS27830	COG0673	inositol 2-dehydrogenase activity
EI981_RS27835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EI981_RS27840	COG0395	ABC-type sugar transport system, permease component
EI981_RS27845	COG1175	transmembrane transport
EI981_RS27850	COG1653	transport
EI981_RS27870	COG1489	DNA binding
EI981_RS27875	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EI981_RS27890	COG0640	Transcriptional regulator
EI981_RS27895	COG2814	Major facilitator Superfamily
EI981_RS27900	COG0840	transmembrane signaling receptor activity
EI981_RS27905	COG0534	Mate efflux family protein
EI981_RS27915	COG0277	FAD linked oxidase domain protein
EI981_RS27965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI981_RS27975	COG2207	Transcriptional regulator
EI981_RS27975	COG3708	Transcriptional regulator
EI981_RS27985	COG2169	Transcriptional regulator
EI981_RS27985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EI981_RS27990	COG0577	efflux transmembrane transporter activity
EI981_RS27995	COG1136	(ABC) transporter
EI981_RS28005	COG3850	Histidine kinase
EI981_RS28005	COG5002	protein histidine kinase activity
EI981_RS28010	COG0745	RESPONSE REGULATOR receiver
EI981_RS28040	COG1175	transmembrane transport
EI981_RS28045	COG1653	transport
EI981_RS28050	COG2972	Histidine kinase
EI981_RS28055	COG2207	Transcriptional regulator
EI981_RS28055	COG4753	response regulator
EI981_RS28095	COG4555	ABC transporter
EI981_RS28100	COG1846	Transcriptional regulator
EI981_RS28120	COG2814	Major facilitator Superfamily
EI981_RS28135	COG5002	protein histidine kinase activity
EI981_RS28140	COG0745	RESPONSE REGULATOR receiver
EI981_RS28165	COG0789	Transcriptional regulator
EI981_RS28190	COG3773	Cell wall hydrolase
EI981_RS28210	COG1388	LysM domain
EI981_RS28210	COG4932	domain protein
EI981_RS28245	COG2205	protein histidine kinase activity
EI981_RS28275	COG1476	TRANSCRIPTIONal
EI981_RS28285	COG2226	methyltransferase
EI981_RS28300	COG1595	DNA-templated transcription, initiation
EI981_RS28315	COG2207	Transcriptional regulator
EI981_RS28315	COG3708	Transcriptional regulator
EI981_RS28360	COG1175	transmembrane transport
EI981_RS28365	COG2182	Extracellular solute-binding protein
EI981_RS28375	COG3384	dioxygenase
EI981_RS28395	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EI981_RS28400	COG0583	DNA-binding transcription factor activity
EI981_RS28405	COG0697	spore germination
EI981_RS28425	COG2378	regulation of single-species biofilm formation
EI981_RS28435	COG2746	aminoglycoside 3-N-acetyltransferase activity
EI981_RS28450	COG5002	protein histidine kinase activity
EI981_RS28500	COG1361	Conserved repeat domain
EI981_RS28510	COG0745	RESPONSE REGULATOR receiver
EI981_RS28510	COG2972	Histidine kinase
EI981_RS28525	COG0322	excinuclease ABC activity
EI981_RS28540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EI981_RS28565	COG0745	RESPONSE REGULATOR receiver
EI981_RS28580	COG2205	protein histidine kinase activity
EI981_RS28590	COG1131	(ABC) transporter
EI981_RS28600	COG0789	Transcriptional regulator
EI981_RS28630	COG0395	ABC-type sugar transport system, permease component
EI981_RS28635	COG4209	transmembrane transport
EI981_RS28640	COG1486	melibiose metabolic process
EI981_RS28650	COG1609	Transcriptional regulator
EI981_RS28660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI981_RS28670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EI981_RS28685	COG5002	protein histidine kinase activity
EI981_RS28690	COG0745	RESPONSE REGULATOR receiver
EI981_RS28695	COG0739	heme binding
EI981_RS28705	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EI981_RS28710	COG0305	Participates in initiation and elongation during chromosome replication
EI981_RS28715	COG0359	binds to the 23S rRNA
EI981_RS28720	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EI981_RS28740	COG1316	TRANSCRIPTIONal
EI981_RS28745	COG4608	Belongs to the ABC transporter superfamily
EI981_RS28750	COG0444	Belongs to the ABC transporter superfamily
EI981_RS28755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI981_RS28760	COG0601	transmembrane transport
EI981_RS28770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EI981_RS28775	COG0629	single-stranded DNA binding
EI981_RS28780	COG0360	Binds together with S18 to 16S ribosomal RNA
EI981_RS28795	COG4481	Protein conserved in bacteria
EI981_RS28800	COG0668	transmembrane transport
EI981_RS28820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EI981_RS28825	COG1475	DNA binding
EI981_RS28830	COG1192	Involved in chromosome partitioning
EI981_RS28835	COG1475	DNA binding
EI981_RS28845	COG0445	tRNA wobble uridine modification
EI981_RS28850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EI981_RS28855	COG1847	R3H domain protein
EI981_RS28865	COG0594	ribonuclease P activity
EI981_RS28870	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EI981_RS28875	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EI981_RS28885	COG1070	Carbohydrate kinase