locus-tag	class	description
BS614_RS00010	COG1256	bacterial-type flagellum assembly
BS614_RS00010	COG4786	Flagellar basal body rod
BS614_RS00030	COG4733	cellulase activity
BS614_RS00030	COG5297	Belongs to the glycosyl hydrolase family 6
BS614_RS00035	COG1040	competence protein
BS614_RS00040	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BS614_RS00070	COG1361	Conserved repeat domain
BS614_RS00080	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BS614_RS00115	COG3693	PFAM glycoside hydrolase, family 10
BS614_RS00120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS614_RS00140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS614_RS00145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BS614_RS00155	COG4786	Flagellar basal body rod
BS614_RS00160	COG4786	Flagellar basal body rod
BS614_RS00170	COG1609	Transcriptional regulator
BS614_RS00175	COG4942	peptidase
BS614_RS00175	COG1388	LysM domain
BS614_RS00180	COG2385	sporulation resulting in formation of a cellular spore
BS614_RS00185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BS614_RS00190	COG4836	Membrane
BS614_RS00195	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BS614_RS00205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BS614_RS00210	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BS614_RS00230	COG0356	it plays a direct role in the translocation of protons across the membrane
BS614_RS00245	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BS614_RS00250	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BS614_RS00255	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BS614_RS00260	COG4475	Protein of unknown function (DUF436)
BS614_RS00265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS614_RS00270	COG1971	Probably functions as a manganese efflux pump
BS614_RS00275	COG0009	L-threonylcarbamoyladenylate synthase
BS614_RS00285	COG0772	Belongs to the SEDS family
BS614_RS00290	COG0772	Belongs to the SEDS family
BS614_RS00295	COG2890	protein-(glutamine-N5) methyltransferase activity
BS614_RS00300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BS614_RS00305	COG0012	GTP binding
BS614_RS00325	COG1304	FMN binding
BS614_RS00335	COG1215	transferase activity, transferring glycosyl groups
BS614_RS00380	COG2076	Multidrug Resistance protein
BS614_RS00385	COG2076	Multidrug Resistance protein
BS614_RS00390	COG1309	transcriptional regulator
BS614_RS00395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BS614_RS00400	COG3835	regulator
BS614_RS00415	COG0167	dihydroorotate dehydrogenase activity
BS614_RS00435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS614_RS00440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS614_RS00445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS614_RS00450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS614_RS00460	COG0840	transmembrane signaling receptor activity
BS614_RS00470	COG0840	transmembrane signaling receptor activity
BS614_RS00475	COG1279	arginine transmembrane transporter activity
BS614_RS00480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS614_RS00500	COG4753	response regulator
BS614_RS00500	COG2207	Transcriptional regulator
BS614_RS00505	COG2972	Histidine kinase
BS614_RS00510	COG1874	Beta-galactosidase
BS614_RS00520	COG0746	molybdenum cofactor guanylyltransferase activity
BS614_RS00540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS00555	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BS614_RS00560	COG3459	Glycosyltransferase 36 associated
BS614_RS00565	COG1609	Transcriptional regulator
BS614_RS00570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS00570	COG2207	Transcriptional regulator
BS614_RS00575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS00580	COG1132	(ABC) transporter
BS614_RS00590	COG1653	transport
BS614_RS00595	COG2972	Histidine kinase
BS614_RS00600	COG1653	transport
BS614_RS00605	COG0395	ABC-type sugar transport system, permease component
BS614_RS00610	COG4209	transmembrane transport
BS614_RS00615	COG2207	Transcriptional regulator
BS614_RS00615	COG4753	response regulator
BS614_RS00620	COG2814	Major facilitator Superfamily
BS614_RS00625	COG0243	molybdopterin cofactor binding
BS614_RS00630	COG2116	formate transmembrane transporter activity
BS614_RS00640	COG0446	pyridine nucleotide-disulphide oxidoreductase
BS614_RS00645	COG0386	Belongs to the glutathione peroxidase family
BS614_RS00650	COG1120	ATPase activity
BS614_RS00700	COG0659	secondary active sulfate transmembrane transporter activity
BS614_RS00705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BS614_RS00730	COG1587	Uroporphyrinogen-III synthase
BS614_RS00750	COG0697	spore germination
BS614_RS00760	COG1741	Belongs to the pirin family
BS614_RS00765	COG2259	Doxx family
BS614_RS00770	COG0501	Belongs to the peptidase M48B family
BS614_RS00780	COG0753	catalase activity
BS614_RS00785	COG0745	RESPONSE REGULATOR receiver
BS614_RS00800	COG0667	Aldo Keto reductase
BS614_RS00810	COG1328	CTP reductase activity
BS614_RS00820	COG0840	transmembrane signaling receptor activity
BS614_RS00830	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS00835	COG0723	plastoquinol--plastocyanin reductase activity
BS614_RS00835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS614_RS00840	COG1695	Transcriptional regulator
BS614_RS00855	COG0300	oxidoreductase activity
BS614_RS00875	COG3384	dioxygenase
BS614_RS00900	COG1177	transmembrane transport
BS614_RS00905	COG1176	ABC-type spermidine putrescine transport system, permease component I
BS614_RS00910	COG3842	ATPase activity
BS614_RS00925	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BS614_RS00930	COG0783	Belongs to the Dps family
BS614_RS00955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BS614_RS00960	COG3842	ATPase activity
BS614_RS00965	COG1177	transmembrane transport
BS614_RS00970	COG1176	ABC-type spermidine putrescine transport system, permease component I
BS614_RS00995	COG3064	Membrane
BS614_RS01005	COG0840	transmembrane signaling receptor activity
BS614_RS01020	COG1309	transcriptional regulator
BS614_RS01035	COG1597	lipid kinase activity
BS614_RS01045	COG3547	Transposase (IS116 IS110 IS902 family)
BS614_RS01050	COG1132	(ABC) transporter
BS614_RS01060	COG1846	Transcriptional regulator
BS614_RS01065	COG1904	glucuronate isomerase
BS614_RS01090	COG1199	ATP-dependent helicase activity
BS614_RS01105	COG2329	Antibiotic biosynthesis monooxygenase
BS614_RS01110	COG1368	sulfuric ester hydrolase activity
BS614_RS01125	COG0456	acetyltransferase
BS614_RS01130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS614_RS01130	COG3153	acetyltransferase
BS614_RS01135	COG0583	DNA-binding transcription factor activity
BS614_RS01140	COG1380	Effector of murein hydrolase LrgA
BS614_RS01145	COG1346	cytolysis
BS614_RS01150	COG2002	toxin-antitoxin pair type II binding
BS614_RS01170	COG1733	regulation of RNA biosynthetic process
BS614_RS01180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BS614_RS01185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BS614_RS01190	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BS614_RS01195	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS614_RS01210	COG0395	ABC-type sugar transport system, permease component
BS614_RS01215	COG1070	Carbohydrate kinase
BS614_RS01230	COG0640	Transcriptional regulator
BS614_RS01240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS614_RS01245	COG0395	ABC-type sugar transport system, permease component
BS614_RS01250	COG1175	transmembrane transport
BS614_RS01265	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BS614_RS01270	COG4988	ABC transporter
BS614_RS01275	COG1294	oxidase, subunit
BS614_RS01280	COG1271	oxidase subunit
BS614_RS01290	COG0463	Glycosyl transferase, family 2
BS614_RS01300	COG0297	glycogen (starch) synthase activity
BS614_RS01305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BS614_RS01310	COG0463	Glycosyl transferase, family 2
BS614_RS01310	COG0457	Tetratricopeptide repeat
BS614_RS01315	COG0463	Glycosyl transferase, family 2
BS614_RS01315	COG0457	Tetratricopeptide repeat
BS614_RS01350	COG0745	RESPONSE REGULATOR receiver
BS614_RS01355	COG1116	anion transmembrane transporter activity
BS614_RS01380	COG1054	Belongs to the UPF0176 family
BS614_RS01390	COG5002	protein histidine kinase activity
BS614_RS01395	COG0745	RESPONSE REGULATOR receiver
BS614_RS01405	COG2207	Transcriptional regulator
BS614_RS01410	COG0534	Mate efflux family protein
BS614_RS01425	COG1653	transport
BS614_RS01430	COG2207	Transcriptional regulator
BS614_RS01435	COG2972	Histidine kinase
BS614_RS01440	COG0395	ABC-type sugar transport system, permease component
BS614_RS01445	COG1175	transmembrane transport
BS614_RS01450	COG1653	transport
BS614_RS01455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BS614_RS01490	COG0488	(ABC) transporter
BS614_RS01510	COG1309	transcriptional regulator
BS614_RS01515	COG2249	NAD(P)H dehydrogenase (quinone) activity
BS614_RS01520	COG1124	(ABC) transporter
BS614_RS01525	COG0444	Belongs to the ABC transporter superfamily
BS614_RS01530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS614_RS01535	COG0601	transmembrane transport
BS614_RS01540	COG0747	negative chemotaxis
BS614_RS01550	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BS614_RS01555	COG0395	ABC-type sugar transport system, permease component
BS614_RS01560	COG1175	transmembrane transport
BS614_RS01565	COG2182	Extracellular solute-binding protein
BS614_RS01570	COG2942	2-epimerase
BS614_RS01575	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BS614_RS01580	COG1609	Transcriptional regulator
BS614_RS01595	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BS614_RS01610	COG1131	(ABC) transporter
BS614_RS01630	COG3212	peptidase
BS614_RS01635	COG3850	Histidine kinase
BS614_RS01635	COG5002	protein histidine kinase activity
BS614_RS01640	COG0745	RESPONSE REGULATOR receiver
BS614_RS01650	COG1252	NADH dehydrogenase
BS614_RS01660	COG1595	DNA-templated transcription, initiation
BS614_RS01675	COG4297	protein containing double-stranded beta helix domain
BS614_RS01695	COG0415	Belongs to the DNA photolyase family
BS614_RS01705	COG0745	RESPONSE REGULATOR receiver
BS614_RS01705	COG2972	Histidine kinase
BS614_RS01710	COG3832	glyoxalase III activity
BS614_RS01720	COG1902	pentaerythritol trinitrate reductase activity
BS614_RS01725	COG1942	4-Oxalocrotonate Tautomerase
BS614_RS01730	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS614_RS01740	COG0840	transmembrane signaling receptor activity
BS614_RS01745	COG1115	amino acid carrier protein
BS614_RS01750	COG0784	Response regulator, receiver
BS614_RS01765	COG1607	acyl-coa hydrolase
BS614_RS01770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BS614_RS01775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS614_RS01780	COG2146	nitrite reductase [NAD(P)H] activity
BS614_RS01815	COG0745	RESPONSE REGULATOR receiver
BS614_RS01835	COG2814	Major facilitator Superfamily
BS614_RS01865	COG0667	Aldo Keto reductase
BS614_RS01880	COG1733	regulation of RNA biosynthetic process
BS614_RS01885	COG2814	Major facilitator Superfamily
BS614_RS01890	COG0656	L-ascorbic acid biosynthetic process
BS614_RS01910	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS614_RS01915	COG1609	Transcriptional regulator
BS614_RS01925	COG0395	ABC-type sugar transport system, permease component
BS614_RS01930	COG4209	transmembrane transport
BS614_RS01940	COG2223	nitrite transmembrane transporter activity
BS614_RS01945	COG1119	ATPase activity
BS614_RS01955	COG1215	transferase activity, transferring glycosyl groups
BS614_RS01965	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BS614_RS01970	COG1846	Transcriptional regulator
BS614_RS01975	COG2153	protein acetylation
BS614_RS01980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BS614_RS01985	COG0733	neurotransmitter:sodium symporter activity
BS614_RS01990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS614_RS02015	COG0322	excinuclease ABC activity
BS614_RS02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS614_RS02055	COG2304	oxidoreductase activity
BS614_RS02060	COG4221	oxidoreductase activity
BS614_RS02090	COG2824	Alkylphosphonate utilization operon protein PhnA
BS614_RS02100	COG2272	Belongs to the type-B carboxylesterase lipase family
BS614_RS02110	COG2076	Multidrug Resistance protein
BS614_RS02130	COG1175	transmembrane transport
BS614_RS02135	COG1510	regulation of RNA biosynthetic process
BS614_RS02145	COG1361	Conserved repeat domain
BS614_RS02155	COG1733	regulation of RNA biosynthetic process
BS614_RS02160	COG1929	Belongs to the glycerate kinase type-1 family
BS614_RS02165	COG1522	sequence-specific DNA binding
BS614_RS02180	COG4589	Belongs to the CDS family
BS614_RS02235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS614_RS02235	COG2169	Transcriptional regulator
BS614_RS02255	COG1131	(ABC) transporter
BS614_RS02275	COG4989	oxidoreductase activity
BS614_RS02280	COG1597	lipid kinase activity
BS614_RS02295	COG2814	Major facilitator Superfamily
BS614_RS02300	COG3693	PFAM glycoside hydrolase, family 10
BS614_RS02305	COG0737	Belongs to the 5'-nucleotidase family
BS614_RS02325	COG3940	Belongs to the glycosyl hydrolase 43 family
BS614_RS02345	COG5566	PFAM Mor transcription activator
BS614_RS02350	COG4221	oxidoreductase activity
BS614_RS02355	COG2378	regulation of single-species biofilm formation
BS614_RS02360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS614_RS02365	COG2755	lipolytic protein G-D-S-L family
BS614_RS02365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BS614_RS02370	COG1309	transcriptional regulator
BS614_RS02375	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BS614_RS02380	COG1126	abc transporter atp-binding protein
BS614_RS02385	COG0765	amino acid transport
BS614_RS02390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS614_RS02395	COG0784	Response regulator, receiver
BS614_RS02400	COG4191	Histidine kinase
BS614_RS02405	COG2972	Histidine kinase
BS614_RS02405	COG0745	RESPONSE REGULATOR receiver
BS614_RS02410	COG3279	Response regulator of the LytR AlgR family
BS614_RS02425	COG1733	regulation of RNA biosynthetic process
BS614_RS02430	COG1846	Transcriptional regulator
BS614_RS02435	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS02470	COG2911	Protein conserved in bacteria
BS614_RS02470	COG1361	Conserved repeat domain
BS614_RS02470	COG3266	domain, Protein
BS614_RS02475	COG3279	Response regulator of the LytR AlgR family
BS614_RS02480	COG2972	Histidine kinase
BS614_RS02480	COG0745	RESPONSE REGULATOR receiver
BS614_RS02485	COG0579	oxidoreductase
BS614_RS02495	COG0444	Belongs to the ABC transporter superfamily
BS614_RS02505	COG0601	transmembrane transport
BS614_RS02510	COG0747	negative chemotaxis
BS614_RS02560	COG2746	aminoglycoside 3-N-acetyltransferase activity
BS614_RS02565	COG2160	L-arabinose isomerase activity
BS614_RS02570	COG0235	Class ii aldolase
BS614_RS02580	COG1609	Transcriptional regulator
BS614_RS02650	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BS614_RS02660	COG4085	toxin activity
BS614_RS02660	COG1525	nuclease
BS614_RS02660	COG0737	Belongs to the 5'-nucleotidase family
BS614_RS02700	COG4640	response to antibiotic
BS614_RS02715	COG1012	belongs to the aldehyde dehydrogenase family
BS614_RS02720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS614_RS02740	COG2267	carboxylic ester hydrolase activity
BS614_RS02765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS614_RS02775	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BS614_RS02785	COG3547	Transposase (IS116 IS110 IS902 family)
BS614_RS02795	COG5002	protein histidine kinase activity
BS614_RS02800	COG0745	RESPONSE REGULATOR receiver
BS614_RS02805	COG0739	heme binding
BS614_RS02820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BS614_RS02825	COG0305	Participates in initiation and elongation during chromosome replication
BS614_RS02830	COG0359	binds to the 23S rRNA
BS614_RS02835	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BS614_RS02855	COG1316	TRANSCRIPTIONal
BS614_RS02860	COG2814	Major facilitator Superfamily
BS614_RS02875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS614_RS02880	COG0601	transmembrane transport
BS614_RS02885	COG4608	Belongs to the ABC transporter superfamily
BS614_RS02890	COG0444	Belongs to the ABC transporter superfamily
BS614_RS02895	COG1876	peptidase activity
BS614_RS02900	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BS614_RS02905	COG0629	single-stranded DNA binding
BS614_RS02910	COG0360	Binds together with S18 to 16S ribosomal RNA
BS614_RS02925	COG4481	Protein conserved in bacteria
BS614_RS02930	COG0668	transmembrane transport
BS614_RS02950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BS614_RS02955	COG1475	DNA binding
BS614_RS02960	COG1192	Involved in chromosome partitioning
BS614_RS02965	COG1475	DNA binding
BS614_RS02975	COG0445	tRNA wobble uridine modification
BS614_RS02980	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BS614_RS02985	COG1847	R3H domain protein
BS614_RS02990	COG0706	membrane insertase activity
BS614_RS02995	COG0594	ribonuclease P activity
BS614_RS03000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BS614_RS03020	COG1070	Carbohydrate kinase
BS614_RS03025	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BS614_RS03030	COG0592	DNA-directed DNA polymerase activity
BS614_RS03035	COG2501	S4 domain
BS614_RS03040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BS614_RS03050	COG0187	DNA topoisomerase II activity
BS614_RS03060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS614_RS03065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BS614_RS03100	COG1982	Orn Lys Arg decarboxylase major
BS614_RS03105	COG3547	Transposase (IS116 IS110 IS902 family)
BS614_RS03110	COG1380	Effector of murein hydrolase LrgA
BS614_RS03115	COG1346	cytolysis
BS614_RS03120	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BS614_RS03125	COG3870	Protein conserved in bacteria
BS614_RS03130	COG1728	Protein conserved in bacteria
BS614_RS03135	COG0470	DNA polymerase III
BS614_RS03140	COG1774	PSP1 C-terminal conserved region
BS614_RS03145	COG4467	Involved in initiation control of chromosome replication
BS614_RS03150	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BS614_RS03155	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BS614_RS03160	COG2002	toxin-antitoxin pair type II binding
BS614_RS03165	COG1078	dGTPase activity
BS614_RS03170	COG0084	hydrolase, TatD family'
BS614_RS03175	COG3583	domain protein
BS614_RS03175	COG3584	3D domain protein
BS614_RS03195	COG4466	Protein conserved in bacteria
BS614_RS03205	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BS614_RS03210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS614_RS03215	COG2088	sporulation resulting in formation of a cellular spore
BS614_RS03225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BS614_RS03230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BS614_RS03250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BS614_RS03255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS614_RS03260	COG2002	toxin-antitoxin pair type II binding
BS614_RS03265	COG2244	polysaccharide biosynthetic process
BS614_RS03270	COG3956	TIGRFAM MazG family protein
BS614_RS03280	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BS614_RS03300	COG1098	S1 RNA binding domain
BS614_RS03305	COG2208	phosphoserine phosphatase activity
BS614_RS03310	COG2304	oxidoreductase activity
BS614_RS03315	COG0515	serine threonine protein kinase
BS614_RS03325	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BS614_RS03330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS614_RS03335	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BS614_RS03340	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BS614_RS03345	COG0157	Belongs to the NadC ModD family
BS614_RS03350	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BS614_RS03360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS614_RS03365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS614_RS03370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BS614_RS03380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS614_RS03385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BS614_RS03390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BS614_RS03395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BS614_RS03400	COG1396	sequence-specific DNA binding
BS614_RS03405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS614_RS03410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS614_RS03420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS614_RS03425	COG3226	Transcriptional regulator
BS614_RS03450	COG0516	GMP reductase activity
BS614_RS03450	COG0517	IMP dehydrogenase activity
BS614_RS03465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BS614_RS03490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS03495	COG0590	tRNA wobble adenosine to inosine editing
BS614_RS03500	COG5002	protein histidine kinase activity
BS614_RS03505	COG1187	pseudouridine synthase activity
BS614_RS03510	COG1360	Flagellar Motor Protein
BS614_RS03515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BS614_RS03530	COG2154	pterin-4-alpha-carbinolamine dehydratase
BS614_RS03535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS614_RS03550	COG0791	NLP P60 protein
BS614_RS03570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS614_RS03575	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BS614_RS03580	COG0010	Belongs to the arginase family
BS614_RS03595	COG3534	alpha-L-arabinofuranosidase
BS614_RS03610	COG0018	arginyl-trna synthetase
BS614_RS03615	COG1404	Belongs to the peptidase S8 family
BS614_RS03620	COG3343	RNA polymerase activity
BS614_RS03630	COG0504	CTP synthase activity
BS614_RS03645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BS614_RS03650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BS614_RS03660	COG0254	rRNA binding
BS614_RS03670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BS614_RS03675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BS614_RS03680	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BS614_RS03760	COG2508	Transcriptional regulator
BS614_RS03765	COG3842	ATPase activity
BS614_RS03770	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BS614_RS03780	COG0546	phosphoglycolate phosphatase activity
BS614_RS03785	COG0110	maltose O-acetyltransferase activity
BS614_RS03790	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BS614_RS03795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BS614_RS03800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BS614_RS03805	COG0131	Imidazoleglycerol-phosphate dehydratase
BS614_RS03810	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BS614_RS03815	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BS614_RS03820	COG0107	imidazoleglycerol-phosphate synthase activity
BS614_RS03825	COG0140	phosphoribosyl-ATP diphosphatase activity
BS614_RS03825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BS614_RS03830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BS614_RS03835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BS614_RS03840	COG2207	Transcriptional regulator
BS614_RS03845	COG1653	transport
BS614_RS03850	COG4209	transmembrane transport
BS614_RS03855	COG0395	ABC-type sugar transport system, permease component
BS614_RS03885	COG0628	permease
BS614_RS03890	COG1940	carbohydrate kinase activity
BS614_RS03895	COG1660	Displays ATPase and GTPase activities
BS614_RS03900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BS614_RS03905	COG1481	regulation of sporulation
BS614_RS03910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS614_RS03925	COG0740	serine-type endopeptidase activity
BS614_RS03945	COG0126	phosphoglycerate kinase activity
BS614_RS03950	COG0149	triose-phosphate isomerase activity
BS614_RS03955	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BS614_RS03960	COG0148	phosphopyruvate hydratase activity
BS614_RS03975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS614_RS03980	COG0557	exoribonuclease II activity
BS614_RS03985	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BS614_RS03995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BS614_RS04085	COG0305	Participates in initiation and elongation during chromosome replication
BS614_RS04100	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BS614_RS04125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BS614_RS04200	COG5518	Phage portal protein
BS614_RS04205	COG2369	cell adhesion
BS614_RS04210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BS614_RS04215	COG4653	Phage capsid family
BS614_RS04265	COG3953	SLT domain
BS614_RS04265	COG5280	Phage tail tape measure protein TP901
BS614_RS04270	COG1652	LysM domain
BS614_RS04275	COG4193	domain, Protein
BS614_RS04285	COG3628	GPW Gp25 family protein
BS614_RS04290	COG3299	homolog of phage Mu protein gp47
BS614_RS04320	COG4824	toxin secretion phage lysis holin
BS614_RS04330	COG0741	lytic transglycosylase activity
BS614_RS04330	COG0739	heme binding
BS614_RS04330	COG1196	nuclear chromosome segregation
BS614_RS04345	COG1598	PFAM Uncharacterised protein family UPF0150
BS614_RS04395	COG2801	Transposase and inactivated derivatives
BS614_RS04405	COG1475	DNA binding
BS614_RS04430	COG2972	Histidine kinase
BS614_RS04440	COG1653	transport
BS614_RS04445	COG1175	transmembrane transport
BS614_RS04450	COG0395	ABC-type sugar transport system, permease component
BS614_RS04460	COG0668	transmembrane transport
BS614_RS04470	COG1819	glycosyl
BS614_RS04485	COG2207	Transcriptional regulator
BS614_RS04485	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS04490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BS614_RS04505	COG3829	transcription factor binding
BS614_RS04515	COG1842	Phage shock protein A
BS614_RS04520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS614_RS04525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BS614_RS04530	COG4260	virion core protein, lumpy skin disease virus
BS614_RS04535	COG4224	UPF0291 protein
BS614_RS04540	COG0346	lactoylglutathione lyase activity
BS614_RS04550	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS04575	COG1082	Xylose isomerase domain protein TIM barrel
BS614_RS04580	COG0673	inositol 2-dehydrogenase activity
BS614_RS04590	COG4209	transmembrane transport
BS614_RS04595	COG0395	ABC-type sugar transport system, permease component
BS614_RS04610	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS04630	COG0789	Transcriptional regulator
BS614_RS04650	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BS614_RS04690	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BS614_RS04695	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BS614_RS04700	COG2205	protein histidine kinase activity
BS614_RS04705	COG2205	protein histidine kinase activity
BS614_RS04710	COG0745	RESPONSE REGULATOR receiver
BS614_RS04715	COG1486	melibiose metabolic process
BS614_RS04735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS614_RS04740	COG0572	uridine kinase
BS614_RS04745	COG3711	transcriptional antiterminator
BS614_RS04750	COG1263	PTS System
BS614_RS04750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS04750	COG2190	(PTS) system
BS614_RS04755	COG2723	6-phospho-beta-galactosidase activity
BS614_RS04775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS614_RS04780	COG4715	Zinc finger, swim domain protein
BS614_RS04780	COG4715	Zinc finger, swim domain protein
BS614_RS04790	COG0840	transmembrane signaling receptor activity
BS614_RS04795	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS614_RS04805	COG1175	transmembrane transport
BS614_RS04810	COG0395	ABC-type sugar transport system, permease component
BS614_RS04815	COG2972	Histidine kinase
BS614_RS04820	COG2204	response regulator
BS614_RS04935	COG3962	Belongs to the TPP enzyme family
BS614_RS04940	COG1082	Xylose isomerase domain protein TIM barrel
BS614_RS04945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS614_RS04950	COG1012	belongs to the aldehyde dehydrogenase family
BS614_RS04955	COG0673	inositol 2-dehydrogenase activity
BS614_RS04960	COG3718	enzyme involved in inositol metabolism
BS614_RS04965	COG1609	Transcriptional regulator
BS614_RS05015	COG0469	pyruvate kinase activity
BS614_RS05040	COG1278	Cold shock
BS614_RS05055	COG2226	methyltransferase
BS614_RS05065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS614_RS05070	COG0765	amino acid transport
BS614_RS05075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BS614_RS05080	COG0010	Belongs to the arginase family
BS614_RS05195	COG2207	Transcriptional regulator
BS614_RS05195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS05220	COG1177	transmembrane transport
BS614_RS05225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS614_RS05240	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS614_RS05245	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BS614_RS05250	COG1737	Transcriptional regulator
BS614_RS05270	COG2971	BadF BadG BcrA BcrD
BS614_RS05285	COG0395	ABC-type sugar transport system, permease component
BS614_RS05290	COG3842	ATPase activity
BS614_RS05300	COG3876	Protein conserved in bacteria
BS614_RS05305	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS05310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS614_RS05315	COG0840	transmembrane signaling receptor activity
BS614_RS05325	COG0840	transmembrane signaling receptor activity
BS614_RS05365	COG4932	domain protein
BS614_RS05365	COG5492	domain, Protein
BS614_RS05370	COG2059	Chromate
BS614_RS05375	COG2059	Chromate
BS614_RS05380	COG1522	sequence-specific DNA binding
BS614_RS05385	COG4585	Histidine kinase
BS614_RS05395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS05410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS614_RS05415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS05425	COG1525	nuclease
BS614_RS05425	COG0737	Belongs to the 5'-nucleotidase family
BS614_RS05425	COG4085	toxin activity
BS614_RS05435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS614_RS05440	COG0840	transmembrane signaling receptor activity
BS614_RS05450	COG1902	pentaerythritol trinitrate reductase activity
BS614_RS05475	COG2814	Major facilitator Superfamily
BS614_RS05480	COG1309	transcriptional regulator
BS614_RS05485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS614_RS05550	COG1122	ATPase activity
BS614_RS05560	COG2972	Histidine kinase
BS614_RS05565	COG2207	Transcriptional regulator
BS614_RS05565	COG4753	response regulator
BS614_RS05585	COG0395	ABC-type sugar transport system, permease component
BS614_RS05590	COG0445	tRNA wobble uridine modification
BS614_RS05595	COG0765	amino acid transport
BS614_RS05600	COG0765	amino acid transport
BS614_RS05605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS614_RS05620	COG2169	Transcriptional regulator
BS614_RS05635	COG1595	DNA-templated transcription, initiation
BS614_RS05640	COG0656	L-ascorbic acid biosynthetic process
BS614_RS05645	COG2733	membrane
BS614_RS05670	COG0745	RESPONSE REGULATOR receiver
BS614_RS05675	COG2205	protein histidine kinase activity
BS614_RS05690	COG2274	protein secretion by the type I secretion system
BS614_RS05710	COG4549	nuclear export factor GLE1
BS614_RS05715	COG2372	response to copper ion
BS614_RS05730	COG2199	diguanylate cyclase activity
BS614_RS05730	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BS614_RS05750	COG3845	ABC transporter
BS614_RS05755	COG4603	Belongs to the binding-protein-dependent transport system permease family
BS614_RS05760	COG1079	Belongs to the binding-protein-dependent transport system permease family
BS614_RS05765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BS614_RS05790	COG2608	mercury ion transmembrane transporter activity
BS614_RS05795	COG2217	Heavy metal translocating P-type atpase
BS614_RS05810	COG0778	Nitroreductase
BS614_RS05815	COG0084	hydrolase, TatD family'
BS614_RS05820	COG1116	anion transmembrane transporter activity
BS614_RS05825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS614_RS05835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS614_RS05840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS614_RS05845	COG0346	lactoylglutathione lyase activity
BS614_RS05855	COG0738	Major facilitator superfamily
BS614_RS05860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BS614_RS05875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BS614_RS05875	COG0456	acetyltransferase
BS614_RS05910	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BS614_RS05915	COG1984	allophanate hydrolase subunit 2
BS614_RS05920	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BS614_RS05930	COG3871	stress protein (general stress protein 26)
BS614_RS05935	COG0737	Belongs to the 5'-nucleotidase family
BS614_RS05945	COG0840	transmembrane signaling receptor activity
BS614_RS05950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS614_RS05955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS614_RS05955	COG3711	transcriptional antiterminator
BS614_RS05965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS614_RS05965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS614_RS05965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS614_RS05970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BS614_RS05975	COG0573	inorganic phosphate transmembrane transporter activity
BS614_RS05980	COG0581	inorganic phosphate transmembrane transporter activity
BS614_RS05985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS614_RS06000	COG1760	l-serine dehydratase
BS614_RS06005	COG1760	l-serine dehydratase
BS614_RS06030	COG2205	protein histidine kinase activity
BS614_RS06065	COG0515	serine threonine protein kinase
BS614_RS06085	COG0024	Methionine aminopeptidase
BS614_RS06090	COG2130	NADP-dependent
BS614_RS06095	COG4846	Membrane protein involved in cytochrome C biogenesis
BS614_RS06115	COG1309	transcriptional regulator
BS614_RS06120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS614_RS06135	COG0778	Nitroreductase
BS614_RS06150	COG2706	6-phosphogluconolactonase activity
BS614_RS06155	COG3401	FG-GAP repeat protein
BS614_RS06170	COG4208	sulfate ABC transporter
BS614_RS06180	COG1653	transport
BS614_RS06185	COG2207	Transcriptional regulator
BS614_RS06190	COG1361	Conserved repeat domain
BS614_RS06220	COG2910	NAD(P)H-binding
BS614_RS06225	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BS614_RS06225	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BS614_RS06230	COG0840	transmembrane signaling receptor activity
BS614_RS06235	COG1744	ABC transporter substrate-binding protein PnrA-like
BS614_RS06240	COG0405	Gamma-glutamyltransferase
BS614_RS06245	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS06250	COG0346	lactoylglutathione lyase activity
BS614_RS06265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS614_RS06300	COG1960	acyl-CoA dehydrogenase activity
BS614_RS06315	COG0010	Belongs to the arginase family
BS614_RS06355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS614_RS06360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS614_RS06365	COG0011	TIGRFAM Protein of
BS614_RS06380	COG1595	DNA-templated transcription, initiation
BS614_RS06390	COG3437	response regulator, receiver
BS614_RS06390	COG2770	Histidine kinase
BS614_RS06400	COG2205	protein histidine kinase activity
BS614_RS06400	COG3437	response regulator, receiver
BS614_RS06400	COG3850	Histidine kinase
BS614_RS06400	COG4999	Histidine kinase
BS614_RS06415	COG0251	oxidation-reduction process
BS614_RS06430	COG2801	Transposase and inactivated derivatives
BS614_RS06440	COG4753	response regulator
BS614_RS06440	COG2207	Transcriptional regulator
BS614_RS06445	COG2972	Histidine kinase
BS614_RS06485	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS614_RS06500	COG1876	peptidase activity
BS614_RS06505	COG0251	oxidation-reduction process
BS614_RS06535	COG0673	inositol 2-dehydrogenase activity
BS614_RS06550	COG0210	DNA helicase
BS614_RS06565	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BS614_RS06575	COG1970	mechanosensitive ion channel activity
BS614_RS06580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS614_RS06610	COG0024	Methionine aminopeptidase
BS614_RS06615	COG2010	Cytochrome c
BS614_RS06615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS614_RS06625	COG1845	cytochrome c oxidase, subunit III
BS614_RS06630	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BS614_RS06635	COG3336	cytochrome c oxidase
BS614_RS06660	COG1725	Transcriptional regulator
BS614_RS06665	COG1131	(ABC) transporter
BS614_RS06670	COG4152	abc transporter atp-binding protein
BS614_RS06675	COG1668	transmembrane transport
BS614_RS06710	COG0534	Mate efflux family protein
BS614_RS06715	COG2226	methyltransferase
BS614_RS06720	COG1595	DNA-templated transcription, initiation
BS614_RS06730	COG1683	Conserved Protein
BS614_RS06735	COG0840	transmembrane signaling receptor activity
BS614_RS06740	COG0778	Nitroreductase
BS614_RS06745	COG1846	Transcriptional regulator
BS614_RS06750	COG2249	NAD(P)H dehydrogenase (quinone) activity
BS614_RS06755	COG0640	Transcriptional regulator
BS614_RS06760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS614_RS06765	COG0628	permease
BS614_RS06770	COG0640	Transcriptional regulator
BS614_RS06775	COG2217	Heavy metal translocating P-type atpase
BS614_RS06780	COG5658	integral membrane protein
BS614_RS06785	COG0789	Transcriptional regulator
BS614_RS06790	COG2814	Major facilitator Superfamily
BS614_RS06800	COG1012	belongs to the aldehyde dehydrogenase family
BS614_RS06810	COG1956	GAF domain-containing protein
BS614_RS06825	COG0477	Major facilitator Superfamily
BS614_RS06830	COG1846	Transcriptional regulator
BS614_RS06835	COG2814	Major facilitator Superfamily
BS614_RS06860	COG1131	(ABC) transporter
BS614_RS06875	COG2081	HI0933 family
BS614_RS06880	COG5002	protein histidine kinase activity
BS614_RS06890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BS614_RS06905	COG1194	a g-specific adenine glycosylase
BS614_RS06915	COG0456	acetyltransferase
BS614_RS06925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BS614_RS06940	COG0302	gtp cyclohydrolase
BS614_RS06945	COG0095	Lipoate-protein ligase
BS614_RS06955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS614_RS06965	COG1414	Transcriptional regulator
BS614_RS06985	COG3708	Transcriptional regulator
BS614_RS06990	COG2378	regulation of single-species biofilm formation
BS614_RS07020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BS614_RS07030	COG1181	Belongs to the D-alanine--D-alanine ligase family
BS614_RS07040	COG4294	response to UV
BS614_RS07045	COG0483	inositol monophosphate 1-phosphatase activity
BS614_RS07060	COG2972	Histidine kinase
BS614_RS07065	COG2207	Transcriptional regulator
BS614_RS07065	COG4753	response regulator
BS614_RS07070	COG1653	transport
BS614_RS07075	COG1175	transmembrane transport
BS614_RS07080	COG0395	ABC-type sugar transport system, permease component
BS614_RS07085	COG2755	lipolytic protein G-D-S-L family
BS614_RS07110	COG0180	Tryptophanyl-tRNA synthetase
BS614_RS07115	COG0697	spore germination
BS614_RS07120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS614_RS07125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS614_RS07130	COG1316	TRANSCRIPTIONal
BS614_RS07135	COG4555	ABC transporter
BS614_RS07150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BS614_RS07175	COG0697	spore germination
BS614_RS07180	COG0586	Pfam SNARE associated Golgi protein
BS614_RS07190	COG0714	Associated with various cellular activities
BS614_RS07200	COG1305	Transglutaminase-like
BS614_RS07210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BS614_RS07210	COG0519	Catalyzes the synthesis of GMP from XMP
BS614_RS07220	COG2252	PERMEase
BS614_RS07245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS614_RS07250	COG0154	amidase activity
BS614_RS07265	COG0589	response to stress
BS614_RS07270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BS614_RS07275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BS614_RS07280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BS614_RS07285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BS614_RS07295	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BS614_RS07300	COG0047	phosphoribosylformylglycinamidine synthase activity
BS614_RS07305	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BS614_RS07310	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BS614_RS07315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BS614_RS07320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BS614_RS07330	COG0151	Belongs to the GarS family
BS614_RS07335	COG1253	flavin adenine dinucleotide binding
BS614_RS07340	COG1253	flavin adenine dinucleotide binding
BS614_RS07345	COG0346	lactoylglutathione lyase activity
BS614_RS07350	COG0400	carboxylic ester hydrolase activity
BS614_RS07365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BS614_RS07370	COG0456	acetyltransferase
BS614_RS07390	COG2207	Transcriptional regulator
BS614_RS07410	COG3384	dioxygenase
BS614_RS07425	COG1470	cell adhesion involved in biofilm formation
BS614_RS07430	COG1392	Phosphate transport regulator
BS614_RS07435	COG0306	phosphate transporter
BS614_RS07440	COG0598	Magnesium transport protein CorA
BS614_RS07445	COG4335	DNA alkylation repair
BS614_RS07455	COG4496	protein, YerC YecD
BS614_RS07470	COG1522	sequence-specific DNA binding
BS614_RS07480	COG1309	transcriptional regulator
BS614_RS07510	COG1597	lipid kinase activity
BS614_RS07515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BS614_RS07540	COG1192	Involved in chromosome partitioning
BS614_RS07545	COG1475	DNA binding
BS614_RS07565	COG0732	type I restriction modification DNA specificity domain
BS614_RS07570	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BS614_RS07575	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BS614_RS07585	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BS614_RS07630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS614_RS07635	COG0318	PFAM AMP-dependent synthetase and ligase
BS614_RS07650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS614_RS07675	COG1131	(ABC) transporter
BS614_RS07695	COG2226	methyltransferase
BS614_RS07735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS614_RS07750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS614_RS07760	COG0398	Pfam SNARE associated Golgi protein
BS614_RS07765	COG0745	RESPONSE REGULATOR receiver
BS614_RS07770	COG0642	Histidine kinase
BS614_RS07770	COG5002	protein histidine kinase activity
BS614_RS07775	COG2272	Belongs to the type-B carboxylesterase lipase family
BS614_RS07790	COG3345	alpha-galactosidase
BS614_RS07795	COG0488	(ABC) transporter
BS614_RS07830	COG3279	Response regulator of the LytR AlgR family
BS614_RS07835	COG0745	RESPONSE REGULATOR receiver
BS614_RS07835	COG2972	Histidine kinase
BS614_RS07840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS614_RS07860	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS614_RS07865	COG5426	von Willebrand factor, type A
BS614_RS07875	COG2972	Histidine kinase
BS614_RS07880	COG4753	response regulator
BS614_RS07880	COG2207	Transcriptional regulator
BS614_RS07890	COG4209	transmembrane transport
BS614_RS07895	COG0395	ABC-type sugar transport system, permease component
BS614_RS07905	COG0657	acetylesterase activity
BS614_RS07915	COG0659	secondary active sulfate transmembrane transporter activity
BS614_RS07925	COG0745	RESPONSE REGULATOR receiver
BS614_RS07945	COG2274	protein secretion by the type I secretion system
BS614_RS07955	COG1301	dicarboxylic acid transport
BS614_RS07965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS614_RS07975	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS07995	COG0784	Response regulator, receiver
BS614_RS07995	COG2205	protein histidine kinase activity
BS614_RS08015	COG0745	RESPONSE REGULATOR receiver
BS614_RS08025	COG1113	amino acid transport
BS614_RS08035	COG0789	Transcriptional regulator
BS614_RS08040	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS08060	COG3459	Glycosyltransferase 36 associated
BS614_RS08080	COG0640	Transcriptional regulator
BS614_RS08175	COG0768	penicillin binding
BS614_RS08180	COG2226	methyltransferase
BS614_RS08195	COG2814	Major facilitator Superfamily
BS614_RS08200	COG2723	6-phospho-beta-galactosidase activity
BS614_RS08205	COG2190	(PTS) system
BS614_RS08205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS08205	COG1263	PTS System
BS614_RS08210	COG3711	transcriptional antiterminator
BS614_RS08245	COG1428	Deoxynucleoside kinase
BS614_RS08250	COG1428	Deoxynucleoside kinase
BS614_RS08265	COG0789	Transcriptional regulator
BS614_RS08270	COG0352	thiamine-phosphate diphosphorylase activity
BS614_RS08275	COG0351	phosphomethylpyrimidine kinase
BS614_RS08280	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BS614_RS08285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS614_RS08290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS614_RS08295	COG1116	anion transmembrane transporter activity
BS614_RS08315	COG1122	ATPase activity
BS614_RS08330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS614_RS08335	COG2011	ABC-type metal ion transport system permease component
BS614_RS08345	COG0840	transmembrane signaling receptor activity
BS614_RS08360	COG0745	RESPONSE REGULATOR receiver
BS614_RS08370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS614_RS08375	COG2223	nitrite transmembrane transporter activity
BS614_RS08380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS614_RS08385	COG0243	molybdopterin cofactor binding
BS614_RS08405	COG2116	formate transmembrane transporter activity
BS614_RS08425	COG0604	alcohol dehydrogenase
BS614_RS08430	COG0583	DNA-binding transcription factor activity
BS614_RS08445	COG0583	DNA-binding transcription factor activity
BS614_RS08450	COG0667	Aldo Keto reductase
BS614_RS08455	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS08455	COG2207	Transcriptional regulator
BS614_RS08465	COG2376	Dihydroxyacetone kinase
BS614_RS08470	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BS614_RS08500	COG3547	Transposase (IS116 IS110 IS902 family)
BS614_RS08510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS08515	COG0454	-acetyltransferase
BS614_RS08525	COG1113	amino acid transport
BS614_RS08535	COG0840	transmembrane signaling receptor activity
BS614_RS08540	COG0583	DNA-binding transcription factor activity
BS614_RS08545	COG1063	alcohol dehydrogenase
BS614_RS08550	COG0454	-acetyltransferase
BS614_RS08595	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS08600	COG1609	Transcriptional regulator
BS614_RS08605	COG2182	Extracellular solute-binding protein
BS614_RS08610	COG1175	transmembrane transport
BS614_RS08615	COG3833	ABC-type maltose transport systems, permease component
BS614_RS08620	COG2814	Major facilitator Superfamily
BS614_RS08640	COG0318	PFAM AMP-dependent synthetase and ligase
BS614_RS08645	COG3547	Transposase (IS116 IS110 IS902 family)
BS614_RS08660	COG1120	ATPase activity
BS614_RS08665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BS614_RS08665	COG0189	ligase activity
BS614_RS08675	COG0477	Major facilitator Superfamily
BS614_RS08680	COG4264	IucA IucC family
BS614_RS08685	COG4264	IucA IucC family
BS614_RS08695	COG0019	diaminopimelate decarboxylase activity
BS614_RS08700	COG4264	IucA IucC family
BS614_RS08710	COG3250	beta-galactosidase activity
BS614_RS08765	COG1061	Type III restriction enzyme res subunit
BS614_RS08840	COG0789	Transcriptional regulator
BS614_RS08845	COG5504	Zn-dependent protease
BS614_RS08895	COG2084	Dehydrogenase
BS614_RS08915	COG2310	stress, protein
BS614_RS08920	COG2310	stress, protein
BS614_RS08925	COG2310	stress, protein
BS614_RS08930	COG2310	stress, protein
BS614_RS08945	COG1358	cellular component organization or biogenesis
BS614_RS08975	COG1132	(ABC) transporter
BS614_RS08980	COG1132	(ABC) transporter
BS614_RS08990	COG0737	Belongs to the 5'-nucleotidase family
BS614_RS09005	COG3639	organic phosphonate transmembrane transporter activity
BS614_RS09040	COG0745	RESPONSE REGULATOR receiver
BS614_RS09045	COG5002	protein histidine kinase activity
BS614_RS09055	COG1136	(ABC) transporter
BS614_RS09060	COG0577	efflux transmembrane transporter activity
BS614_RS09060	COG1136	(ABC) transporter
BS614_RS09070	COG5297	Belongs to the glycosyl hydrolase family 6
BS614_RS09075	COG3401	FG-GAP repeat protein
BS614_RS09085	COG2207	Transcriptional regulator
BS614_RS09090	COG1486	melibiose metabolic process
BS614_RS09110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS614_RS09115	COG0765	amino acid transport
BS614_RS09120	COG1126	abc transporter atp-binding protein
BS614_RS09135	COG1511	domain protein
BS614_RS09140	COG1309	transcriptional regulator
BS614_RS09185	COG1518	maintenance of DNA repeat elements
BS614_RS09190	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BS614_RS09205	COG1942	4-Oxalocrotonate Tautomerase
BS614_RS09210	COG4209	transmembrane transport
BS614_RS09215	COG0395	ABC-type sugar transport system, permease component
BS614_RS09220	COG2207	Transcriptional regulator
BS614_RS09220	COG4753	response regulator
BS614_RS09225	COG2972	Histidine kinase
BS614_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS09240	COG1653	transport
BS614_RS09260	COG0776	regulation of translation
BS614_RS09265	COG1278	Cold shock
BS614_RS09275	COG2207	Transcriptional regulator
BS614_RS09275	COG4753	response regulator
BS614_RS09280	COG2972	Histidine kinase
BS614_RS09285	COG1879	ABC-type sugar transport system periplasmic component
BS614_RS09300	COG4211	Belongs to the binding-protein-dependent transport system permease family
BS614_RS09310	COG5002	protein histidine kinase activity
BS614_RS09315	COG1132	(ABC) transporter
BS614_RS09320	COG1132	(ABC) transporter
BS614_RS09325	COG1846	Transcriptional regulator
BS614_RS09350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS09355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS614_RS09360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS614_RS09365	COG2207	Transcriptional regulator
BS614_RS09365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS09375	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BS614_RS09380	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BS614_RS09385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BS614_RS09390	COG1725	Transcriptional regulator
BS614_RS09395	COG1131	(ABC) transporter
BS614_RS09415	COG0657	acetylesterase activity
BS614_RS09420	COG0864	Transcriptional regulator
BS614_RS09430	COG0601	transmembrane transport
BS614_RS09440	COG0444	Belongs to the ABC transporter superfamily
BS614_RS09445	COG1124	(ABC) transporter
BS614_RS09450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BS614_RS09460	COG4946	Tricorn protease homolog
BS614_RS09460	COG1506	peptidase
BS614_RS09460	COG0823	Involved in the tonB-independent uptake of proteins
BS614_RS09470	COG0656	L-ascorbic acid biosynthetic process
BS614_RS09475	COG1725	Transcriptional regulator
BS614_RS09480	COG1131	(ABC) transporter
BS614_RS09510	COG3541	Predicted nucleotidyltransferase
BS614_RS09540	COG1595	DNA-templated transcription, initiation
BS614_RS09560	COG0673	inositol 2-dehydrogenase activity
BS614_RS09585	COG2112	serine threonine protein kinase
BS614_RS09595	COG0686	Belongs to the AlaDH PNT family
BS614_RS09610	COG3290	protein histidine kinase activity
BS614_RS09610	COG3829	transcription factor binding
BS614_RS09630	COG0506	proline dehydrogenase activity
BS614_RS09635	COG1012	belongs to the aldehyde dehydrogenase family
BS614_RS09645	COG1027	Aspartate ammonia-lyase
BS614_RS09650	COG0840	transmembrane signaling receptor activity
BS614_RS09665	COG0346	lactoylglutathione lyase activity
BS614_RS09670	COG5522	Integral membrane protein (intg_mem_TP0381)
BS614_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS09685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS614_RS09710	COG2205	protein histidine kinase activity
BS614_RS09740	COG0840	transmembrane signaling receptor activity
BS614_RS09750	COG4447	cellulose binding
BS614_RS09750	COG5297	Belongs to the glycosyl hydrolase family 6
BS614_RS09775	COG3547	Transposase (IS116 IS110 IS902 family)
BS614_RS09780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BS614_RS09785	COG1522	sequence-specific DNA binding
BS614_RS09795	COG1132	(ABC) transporter
BS614_RS09800	COG1132	(ABC) transporter
BS614_RS09810	COG4209	transmembrane transport
BS614_RS09815	COG0395	ABC-type sugar transport system, permease component
BS614_RS09845	COG4977	sequence-specific DNA binding
BS614_RS09845	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS09850	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS09855	COG4977	sequence-specific DNA binding
BS614_RS09860	COG0640	Transcriptional regulator
BS614_RS09875	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS09890	COG0395	ABC-type sugar transport system, permease component
BS614_RS09895	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS09900	COG3940	Belongs to the glycosyl hydrolase 43 family
BS614_RS09905	COG2217	Heavy metal translocating P-type atpase
BS614_RS09910	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
BS614_RS09915	COG2223	nitrite transmembrane transporter activity
BS614_RS09935	COG0720	synthase
BS614_RS09940	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BS614_RS09970	COG0442	prolyl-tRNA aminoacylation
BS614_RS09975	COG0737	Belongs to the 5'-nucleotidase family
BS614_RS09985	COG1396	sequence-specific DNA binding
BS614_RS09995	COG4585	Histidine kinase
BS614_RS09995	COG2203	Gaf domain
BS614_RS10000	COG2197	response regulator
BS614_RS10065	COG1652	LysM domain
BS614_RS10085	COG3299	homolog of phage Mu protein gp47
BS614_RS10095	COG5301	cellulose 1,4-beta-cellobiosidase activity
BS614_RS10150	COG3628	GPW Gp25 family protein
BS614_RS10155	COG3299	homolog of phage Mu protein gp47
BS614_RS10185	COG4824	toxin secretion phage lysis holin
BS614_RS10195	COG0747	negative chemotaxis
BS614_RS10200	COG0601	transmembrane transport
BS614_RS10205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS614_RS10215	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BS614_RS10220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS614_RS10225	COG0840	transmembrane signaling receptor activity
BS614_RS10245	COG3773	Cell wall hydrolase
BS614_RS10250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS614_RS10255	COG1309	transcriptional regulator
BS614_RS10260	COG1511	domain protein
BS614_RS10265	COG0069	glutamate synthase activity
BS614_RS10265	COG0067	glutamate synthase
BS614_RS10265	COG0070	glutamate synthase
BS614_RS10285	COG4464	protein tyrosine phosphatase activity
BS614_RS10290	COG3944	biosynthesis protein
BS614_RS10295	COG0489	protein tyrosine kinase activity
BS614_RS10300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS614_RS10305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BS614_RS10325	COG0438	transferase activity, transferring glycosyl groups
BS614_RS10330	COG1215	transferase activity, transferring glycosyl groups
BS614_RS10340	COG1216	Glycosyl transferase, family 2
BS614_RS10350	COG5039	Polysaccharide pyruvyl transferase
BS614_RS10360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS614_RS10365	COG1316	TRANSCRIPTIONal
BS614_RS10390	COG1131	(ABC) transporter
BS614_RS10395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS614_RS10400	COG0628	permease
BS614_RS10405	COG2188	Transcriptional regulator
BS614_RS10415	COG1073	alpha beta
BS614_RS10420	COG1253	flavin adenine dinucleotide binding
BS614_RS10425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS614_RS10430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS614_RS10435	COG3285	dna ligase
BS614_RS10435	COG1793	dna ligase
BS614_RS10450	COG2514	catechol 2,3-dioxygenase activity
BS614_RS10455	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BS614_RS10470	COG0802	atpase or kinase
BS614_RS10475	COG1214	PFAM Peptidase M22, glycoprotease
BS614_RS10480	COG0456	acetyltransferase
BS614_RS10485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BS614_RS10495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS614_RS10500	COG0488	(ABC) transporter
BS614_RS10505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BS614_RS10510	COG0315	cyclic pyranopterin monophosphate synthase activity
BS614_RS10515	COG0521	Mo-molybdopterin cofactor biosynthetic process
BS614_RS10520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS614_RS10525	COG0805	protein transport
BS614_RS10530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BS614_RS10535	COG0459	protein refolding
BS614_RS10540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BS614_RS10545	COG2169	Transcriptional regulator
BS614_RS10550	COG1744	ABC transporter substrate-binding protein PnrA-like
BS614_RS10555	COG3845	ABC transporter
BS614_RS10565	COG1079	Belongs to the binding-protein-dependent transport system permease family
BS614_RS10590	COG2072	flavoprotein involved in K transport
BS614_RS10635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS10645	COG0235	Class ii aldolase
BS614_RS10650	COG0531	amino acid
BS614_RS10655	COG1175	transmembrane transport
BS614_RS10660	COG0395	ABC-type sugar transport system, permease component
BS614_RS10665	COG1653	transport
BS614_RS10670	COG0737	Belongs to the 5'-nucleotidase family
BS614_RS10685	COG2113	Glycine betaine
BS614_RS10690	COG0517	IMP dehydrogenase activity
BS614_RS10690	COG4175	Glycine betaine
BS614_RS10695	COG1510	regulation of RNA biosynthetic process
BS614_RS10710	COG0673	inositol 2-dehydrogenase activity
BS614_RS10715	COG0673	inositol 2-dehydrogenase activity
BS614_RS10730	COG1131	(ABC) transporter
BS614_RS10735	COG0326	Molecular chaperone. Has ATPase activity
BS614_RS10755	COG1476	TRANSCRIPTIONal
BS614_RS10765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS614_RS10770	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BS614_RS10775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BS614_RS10780	COG0864	Transcriptional regulator
BS614_RS10785	COG2337	Toxic component of a toxin-antitoxin (TA) module
BS614_RS10795	COG2183	response to ionizing radiation
BS614_RS10820	COG0640	Transcriptional regulator
BS614_RS10825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS614_RS10830	COG1285	pathogenesis
BS614_RS10840	COG1349	DNA-binding transcription factor activity
BS614_RS10865	COG0829	nickel cation binding
BS614_RS10875	COG0830	nickel cation binding
BS614_RS10890	COG0831	urea catabolic process
BS614_RS10915	COG1137	ATPase activity
BS614_RS10930	COG0830	nickel cation binding
BS614_RS10945	COG0386	Belongs to the glutathione peroxidase family
BS614_RS10955	COG1011	Hydrolase
BS614_RS10965	COG1764	response to oxidative stress
BS614_RS10980	COG3011	Protein conserved in bacteria
BS614_RS11045	COG1090	epimerase
BS614_RS11055	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BS614_RS11060	COG0788	formyltetrahydrofolate deformylase activity
BS614_RS11080	COG0166	Belongs to the GPI family
BS614_RS11085	COG1739	Uncharacterized protein family UPF0029
BS614_RS11090	COG1309	transcriptional regulator
BS614_RS11095	COG0432	Pfam Uncharacterised protein family UPF0047
BS614_RS11105	COG4208	sulfate ABC transporter
BS614_RS11110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BS614_RS11115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BS614_RS11125	COG0321	lipoyl(octanoyl) transferase activity
BS614_RS11125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BS614_RS11135	COG0740	serine-type endopeptidase activity
BS614_RS11140	COG1725	Transcriptional regulator
BS614_RS11145	COG1131	(ABC) transporter
BS614_RS11155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS614_RS11175	COG2801	Transposase and inactivated derivatives
BS614_RS11190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS614_RS11195	COG0561	phosphatase activity
BS614_RS11200	COG0095	Lipoate-protein ligase
BS614_RS11205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BS614_RS11215	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BS614_RS11220	COG0588	phosphoglycerate mutase activity
BS614_RS11225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS11230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS614_RS11235	COG1120	ATPase activity
BS614_RS11240	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BS614_RS11250	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BS614_RS11255	COG1492	cobalamin metabolic process
BS614_RS11260	COG0840	transmembrane signaling receptor activity
BS614_RS11270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BS614_RS11280	COG2801	Transposase and inactivated derivatives
BS614_RS11290	COG0006	proline dipeptidase activity
BS614_RS11295	COG2133	pyrroloquinoline quinone binding
BS614_RS11315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS614_RS11320	COG2205	protein histidine kinase activity
BS614_RS11325	COG0745	RESPONSE REGULATOR receiver
BS614_RS11335	COG1247	-acetyltransferase
BS614_RS11340	COG2318	DinB family
BS614_RS11350	COG0004	ammonium transporteR
BS614_RS11385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS614_RS11395	COG3610	response to peptide
BS614_RS11400	COG2966	Psort location CytoplasmicMembrane, score
BS614_RS11410	COG1619	proteins homologs of microcin C7 resistance protein MccF
BS614_RS11420	COG1595	DNA-templated transcription, initiation
BS614_RS11430	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS11430	COG2207	Transcriptional regulator
BS614_RS11450	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BS614_RS11455	COG4474	Belongs to the UPF0398 family
BS614_RS11480	COG1086	Polysaccharide biosynthesis protein
BS614_RS11490	COG2226	methyltransferase
BS614_RS11495	COG0463	Glycosyl transferase, family 2
BS614_RS11515	COG1132	(ABC) transporter
BS614_RS11520	COG1132	(ABC) transporter
BS614_RS11530	COG0514	ATP-dependent DNA helicase (RecQ)
BS614_RS11670	COG4974	Belongs to the 'phage' integrase family
BS614_RS11765	COG4753	response regulator
BS614_RS11765	COG2207	Transcriptional regulator
BS614_RS11770	COG2972	Histidine kinase
BS614_RS11775	COG4209	transmembrane transport
BS614_RS11780	COG0395	ABC-type sugar transport system, permease component
BS614_RS11810	COG2249	NAD(P)H dehydrogenase (quinone) activity
BS614_RS11815	COG1733	regulation of RNA biosynthetic process
BS614_RS11820	COG0494	nUDIX hydrolase
BS614_RS11845	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BS614_RS11890	COG0745	RESPONSE REGULATOR receiver
BS614_RS11900	COG0577	efflux transmembrane transporter activity
BS614_RS11905	COG1136	(ABC) transporter
BS614_RS11945	COG0259	pyridoxamine-phosphate oxidase activity
BS614_RS11950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS11955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BS614_RS12025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS12060	COG0464	growth
BS614_RS12080	COG0590	tRNA wobble adenosine to inosine editing
BS614_RS12095	COG0384	phenazine biosynthesis protein PhzF
BS614_RS12110	COG0494	nUDIX hydrolase
BS614_RS12150	COG0561	phosphatase activity
BS614_RS12160	COG1011	Hydrolase
BS614_RS12195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS614_RS12200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS614_RS12205	COG0383	alpha-mannosidase activity
BS614_RS12210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS614_RS12210	COG3711	transcriptional antiterminator
BS614_RS12215	COG4326	sporulation control protein
BS614_RS12240	COG2318	DinB family
BS614_RS12255	COG0500	methyltransferase
BS614_RS12260	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS12265	COG0745	RESPONSE REGULATOR receiver
BS614_RS12270	COG0642	Histidine kinase
BS614_RS12275	COG1136	(ABC) transporter
BS614_RS12280	COG0577	efflux transmembrane transporter activity
BS614_RS12290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BS614_RS12310	COG1690	Belongs to the RtcB family
BS614_RS12320	COG1609	Transcriptional regulator
BS614_RS12330	COG1653	transport
BS614_RS12340	COG0395	ABC-type sugar transport system, permease component
BS614_RS12360	COG1175	transmembrane transport
BS614_RS12365	COG0395	ABC-type sugar transport system, permease component
BS614_RS12370	COG4124	Belongs to the glycosyl hydrolase 26 family
BS614_RS12385	COG1653	transport
BS614_RS12390	COG4209	transmembrane transport
BS614_RS12395	COG0395	ABC-type sugar transport system, permease component
BS614_RS12400	COG2207	Transcriptional regulator
BS614_RS12405	COG3119	arylsulfatase activity
BS614_RS12410	COG3401	FG-GAP repeat protein
BS614_RS12415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BS614_RS12435	COG2207	Transcriptional regulator
BS614_RS12435	COG3708	Transcriptional regulator
BS614_RS12465	COG1090	epimerase
BS614_RS12470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS614_RS12480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS614_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS12505	COG1247	-acetyltransferase
BS614_RS12530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS614_RS12545	COG1072	(Pantothenic acid kinase))
BS614_RS12560	COG0456	acetyltransferase
BS614_RS12565	COG0567	Dehydrogenase, E1 component
BS614_RS12570	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS614_RS12580	COG1482	cell wall glycoprotein biosynthetic process
BS614_RS12585	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BS614_RS12590	COG1242	4 iron, 4 sulfur cluster binding
BS614_RS12600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BS614_RS12610	COG4209	transmembrane transport
BS614_RS12615	COG0395	ABC-type sugar transport system, permease component
BS614_RS12625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS614_RS12630	COG0671	phosphoesterase, PA-phosphatase related
BS614_RS12635	COG1215	transferase activity, transferring glycosyl groups
BS614_RS12645	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BS614_RS12650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BS614_RS12655	COG1744	ABC transporter substrate-binding protein PnrA-like
BS614_RS12660	COG3845	ABC transporter
BS614_RS12665	COG4603	Belongs to the binding-protein-dependent transport system permease family
BS614_RS12670	COG1079	Belongs to the binding-protein-dependent transport system permease family
BS614_RS12685	COG0028	Belongs to the TPP enzyme family
BS614_RS12690	COG0440	acetolactate synthase activity
BS614_RS12695	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BS614_RS12700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS614_RS12705	COG0667	Aldo Keto reductase
BS614_RS12710	COG0473	3-isopropylmalate dehydrogenase activity
BS614_RS12725	COG3852	Histidine kinase
BS614_RS12730	COG0714	Associated with various cellular activities
BS614_RS12745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS614_RS12760	COG0488	(ABC) transporter
BS614_RS12765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BS614_RS12775	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BS614_RS12790	COG1193	negative regulation of DNA recombination
BS614_RS12795	COG3766	membrane
BS614_RS12805	COG0477	Major facilitator Superfamily
BS614_RS12810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS614_RS12825	COG1522	sequence-specific DNA binding
BS614_RS12830	COG0436	Aminotransferase
BS614_RS12850	COG0586	Pfam SNARE associated Golgi protein
BS614_RS12855	COG2096	Adenosyltransferase
BS614_RS12860	COG0564	pseudouridine synthase activity
BS614_RS12865	COG1393	Belongs to the ArsC family
BS614_RS12870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS614_RS12880	COG2258	MOSC domain
BS614_RS12885	COG1940	carbohydrate kinase activity
BS614_RS12895	COG0598	Magnesium transport protein CorA
BS614_RS12900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BS614_RS12905	COG0626	cystathionine gamma-synthase activity
BS614_RS12910	COG0626	cystathionine gamma-synthase activity
BS614_RS12915	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BS614_RS12920	COG0667	Aldo Keto reductase
BS614_RS12925	COG1063	alcohol dehydrogenase
BS614_RS12930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS614_RS12935	COG0475	glutathione-regulated potassium exporter activity
BS614_RS12940	COG0490	domain, Protein
BS614_RS12955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS614_RS12960	COG3584	3D domain protein
BS614_RS12970	COG4758	membrane
BS614_RS12975	COG4585	Histidine kinase
BS614_RS12980	COG2197	response regulator
BS614_RS12985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS614_RS12995	COG5002	protein histidine kinase activity
BS614_RS12995	COG3850	Histidine kinase
BS614_RS13000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BS614_RS13005	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BS614_RS13010	COG0174	glutamine synthetase
BS614_RS13020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BS614_RS13025	COG2002	toxin-antitoxin pair type II binding
BS614_RS13040	COG4209	transmembrane transport
BS614_RS13045	COG0395	ABC-type sugar transport system, permease component
BS614_RS13065	COG4632	Exopolysaccharide biosynthesis protein
BS614_RS13065	COG5434	Belongs to the glycosyl hydrolase 28 family
BS614_RS13080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS614_RS13095	COG2766	serine protein kinase
BS614_RS13100	COG0840	transmembrane signaling receptor activity
BS614_RS13125	COG3550	peptidyl-serine autophosphorylation
BS614_RS13135	COG2719	SpoVR family
BS614_RS13140	COG2718	Belongs to the UPF0229 family
BS614_RS13145	COG2270	Major facilitator Superfamily
BS614_RS13150	COG3551	Protein conserved in bacteria
BS614_RS13180	COG1132	(ABC) transporter
BS614_RS13185	COG0529	Catalyzes the synthesis of activated sulfate
BS614_RS13210	COG2363	Small membrane protein
BS614_RS13230	COG3377	Domain of unknown function (DUF1805)
BS614_RS13245	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BS614_RS13250	COG0783	Belongs to the Dps family
BS614_RS13260	COG0396	ATPase activity
BS614_RS13265	COG0719	Fe-S assembly protein
BS614_RS13270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BS614_RS13275	COG0822	iron-sulfur transferase activity
BS614_RS13280	COG0719	Fe-S assembly protein
BS614_RS13290	COG0739	heme binding
BS614_RS13290	COG1196	nuclear chromosome segregation
BS614_RS13290	COG0741	lytic transglycosylase activity
BS614_RS13300	COG0314	molybdopterin synthase activity
BS614_RS13305	COG0737	Belongs to the 5'-nucleotidase family
BS614_RS13315	COG0535	radical SAM domain protein
BS614_RS13320	COG1253	flavin adenine dinucleotide binding
BS614_RS13335	COG3546	catalase activity
BS614_RS13345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS614_RS13365	COG0673	inositol 2-dehydrogenase activity
BS614_RS13370	COG0840	transmembrane signaling receptor activity
BS614_RS13380	COG1175	transmembrane transport
BS614_RS13385	COG0395	ABC-type sugar transport system, permease component
BS614_RS13390	COG2972	Histidine kinase
BS614_RS13395	COG4753	response regulator
BS614_RS13395	COG2207	Transcriptional regulator
BS614_RS13415	COG0189	ligase activity
BS614_RS13425	COG0189	ligase activity
BS614_RS13430	COG0189	ligase activity
BS614_RS13435	COG0189	ligase activity
BS614_RS13440	COG3679	Belongs to the UPF0342 family
BS614_RS13450	COG4109	DRTGG domain
BS614_RS13475	COG0587	DNA-directed DNA polymerase activity
BS614_RS13480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS614_RS13495	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BS614_RS13500	COG0825	malonyl-CoA metabolic process
BS614_RS13505	COG0469	pyruvate kinase activity
BS614_RS13510	COG0824	Thioesterase
BS614_RS13515	COG3030	protein affecting phage T7 exclusion by the F plasmid
BS614_RS13520	COG0628	permease
BS614_RS13525	COG0372	Belongs to the citrate synthase family
BS614_RS13530	COG0538	isocitrate dehydrogenase activity
BS614_RS13550	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS13555	COG5002	protein histidine kinase activity
BS614_RS13560	COG0745	RESPONSE REGULATOR receiver
BS614_RS13565	COG0840	transmembrane signaling receptor activity
BS614_RS13570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS614_RS13575	COG0704	Plays a role in the regulation of phosphate uptake
BS614_RS13585	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BS614_RS13590	COG1971	Probably functions as a manganese efflux pump
BS614_RS13595	COG0237	dephospho-CoA kinase activity
BS614_RS13600	COG0741	lytic transglycosylase activity
BS614_RS13610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BS614_RS13665	COG2267	carboxylic ester hydrolase activity
BS614_RS13675	COG0277	FAD linked oxidase domain protein
BS614_RS13685	COG0778	Nitroreductase
BS614_RS13690	COG1846	Transcriptional regulator
BS614_RS13700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS13740	COG4224	UPF0291 protein
BS614_RS13745	COG2072	flavoprotein involved in K transport
BS614_RS13760	COG1349	DNA-binding transcription factor activity
BS614_RS13765	COG1105	Belongs to the carbohydrate kinase PfkB family
BS614_RS13770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS614_RS13770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS614_RS13770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS614_RS13775	COG2226	methyltransferase
BS614_RS13780	COG1063	alcohol dehydrogenase
BS614_RS13785	COG2140	Oxalate decarboxylase
BS614_RS13790	COG0300	oxidoreductase activity
BS614_RS13795	COG0789	Transcriptional regulator
BS614_RS13800	COG2207	Transcriptional regulator
BS614_RS13805	COG0583	DNA-binding transcription factor activity
BS614_RS13815	COG3706	GGDEF domain
BS614_RS13820	COG1733	regulation of RNA biosynthetic process
BS614_RS13830	COG0673	inositol 2-dehydrogenase activity
BS614_RS13845	COG0371	Dehydrogenase
BS614_RS13855	COG4824	toxin secretion phage lysis holin
BS614_RS13865	COG2445	Protein of unknown function DUF86
BS614_RS13875	COG4980	gas vesicle protein
BS614_RS13880	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS614_RS13910	COG0656	L-ascorbic acid biosynthetic process
BS614_RS13915	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BS614_RS13925	COG1368	sulfuric ester hydrolase activity
BS614_RS13930	COG0116	Belongs to the methyltransferase superfamily
BS614_RS13935	COG4122	O-methyltransferase activity
BS614_RS13940	COG0252	asparaginase activity
BS614_RS13955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BS614_RS13960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BS614_RS13965	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BS614_RS13970	COG2843	Capsule synthesis protein
BS614_RS13975	COG0584	glycerophosphoryl diester phosphodiesterase
BS614_RS13980	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS614_RS13990	COG1846	Transcriptional regulator
BS614_RS14010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS614_RS14020	COG1309	transcriptional regulator
BS614_RS14025	COG0488	(ABC) transporter
BS614_RS14035	COG1363	Peptidase, m42
BS614_RS14045	COG1164	Oligoendopeptidase f
BS614_RS14060	COG1278	Cold shock
BS614_RS14085	COG0534	Mate efflux family protein
BS614_RS14100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS614_RS14105	COG0513	Belongs to the DEAD box helicase family
BS614_RS14110	COG5578	integral membrane protein
BS614_RS14125	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BS614_RS14130	COG0705	Rhomboid family
BS614_RS14135	COG0583	DNA-binding transcription factor activity
BS614_RS14140	COG2738	Putative neutral zinc metallopeptidase
BS614_RS14150	COG0004	ammonium transporteR
BS614_RS14160	COG2176	DNA-directed DNA polymerase activity
BS614_RS14170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS614_RS14175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS614_RS14180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS614_RS14185	COG1141	Ferredoxin
BS614_RS14195	COG0167	dihydroorotate dehydrogenase activity
BS614_RS14200	COG2357	RelA SpoT domain protein
BS614_RS14210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS614_RS14215	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BS614_RS14215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BS614_RS14220	COG1187	pseudouridine synthase activity
BS614_RS14225	COG0561	phosphatase activity
BS614_RS14235	COG0454	-acetyltransferase
BS614_RS14245	COG3949	Membrane
BS614_RS14250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS614_RS14270	COG0791	NLP P60 protein
BS614_RS14270	COG1388	LysM domain
BS614_RS14285	COG5520	Belongs to the glycosyl hydrolase 30 family
BS614_RS14290	COG2861	carbohydrate metabolic process
BS614_RS14330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS614_RS14335	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BS614_RS14335	COG2755	lipolytic protein G-D-S-L family
BS614_RS14345	COG1175	transmembrane transport
BS614_RS14350	COG0395	ABC-type sugar transport system, permease component
BS614_RS14355	COG2972	Histidine kinase
BS614_RS14360	COG2207	Transcriptional regulator
BS614_RS14360	COG4753	response regulator
BS614_RS14380	COG1846	Transcriptional regulator
BS614_RS14390	COG0025	NhaP-type Na H and K H
BS614_RS14395	COG0667	Aldo Keto reductase
BS614_RS14405	COG4895	conserved protein (DUF2196)
BS614_RS14415	COG3069	C4-dicarboxylate transmembrane transporter activity
BS614_RS14425	COG2207	Transcriptional regulator
BS614_RS14430	COG4209	transmembrane transport
BS614_RS14435	COG0395	ABC-type sugar transport system, permease component
BS614_RS14440	COG1653	transport
BS614_RS14450	COG3275	phosphorelay sensor kinase activity
BS614_RS14455	COG2207	Transcriptional regulator
BS614_RS14455	COG4753	response regulator
BS614_RS14460	COG1653	transport
BS614_RS14465	COG4209	transmembrane transport
BS614_RS14470	COG0395	ABC-type sugar transport system, permease component
BS614_RS14480	COG1874	Beta-galactosidase
BS614_RS14490	COG1418	mRNA catabolic process
BS614_RS14495	COG4129	membrane
BS614_RS14505	COG3973	AAA domain
BS614_RS14510	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BS614_RS14520	COG2207	Transcriptional regulator
BS614_RS14520	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS14525	COG1501	Belongs to the glycosyl hydrolase 31 family
BS614_RS14535	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS14540	COG2814	Major facilitator Superfamily
BS614_RS14550	COG1846	Transcriptional regulator
BS614_RS14555	COG4154	Belongs to the RbsD FucU family
BS614_RS14560	COG0456	acetyltransferase
BS614_RS14570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS614_RS14590	COG1846	Transcriptional regulator
BS614_RS14600	COG2205	protein histidine kinase activity
BS614_RS14600	COG2198	Histidine kinase
BS614_RS14600	COG0784	Response regulator, receiver
BS614_RS14610	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BS614_RS14625	COG1033	growth of symbiont in host cell
BS614_RS14625	COG2409	Drug exporters of the RND superfamily
BS614_RS14630	COG2755	lipolytic protein G-D-S-L family
BS614_RS14655	COG0246	Mannitol dehydrogenase
BS614_RS14660	COG2721	sulfolactate sulfo-lyase activity
BS614_RS14670	COG2378	regulation of single-species biofilm formation
BS614_RS14695	COG3386	PFAM SMP-30 Gluconolaconase
BS614_RS14705	COG2207	Transcriptional regulator
BS614_RS14705	COG4753	response regulator
BS614_RS14710	COG2972	Histidine kinase
BS614_RS14730	COG3250	beta-galactosidase activity
BS614_RS14750	COG0742	ribosomal rna small subunit methyltransferase
BS614_RS14755	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BS614_RS14760	COG3314	Sporulation integral membrane protein YlbJ
BS614_RS14765	COG3480	Lon protease (S16) C-terminal proteolytic domain
BS614_RS14770	COG1323	Belongs to the UPF0348 family
BS614_RS14785	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BS614_RS14790	COG1349	DNA-binding transcription factor activity
BS614_RS14795	COG0416	fatty acid biosynthetic process
BS614_RS14805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BS614_RS14810	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS14815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS614_RS14820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS614_RS14825	COG0571	ribonuclease III activity
BS614_RS14830	COG1196	nuclear chromosome segregation
BS614_RS14835	COG0552	protein localization to endoplasmic reticulum
BS614_RS14840	COG1272	protein, Hemolysin III
BS614_RS14845	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BS614_RS14850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BS614_RS14855	COG0228	four-way junction DNA binding
BS614_RS14865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BS614_RS14885	COG0726	polysaccharide deacetylase
BS614_RS14890	COG0335	large ribosomal subunit rRNA binding
BS614_RS14905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BS614_RS14915	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS614_RS14920	COG0792	nuclease activity
BS614_RS14930	COG0778	Nitroreductase
BS614_RS14940	COG1846	Transcriptional regulator
BS614_RS14945	COG0045	succinate-CoA ligase (ADP-forming) activity
BS614_RS14950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BS614_RS14960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS614_RS14965	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BS614_RS14970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BS614_RS14975	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BS614_RS14980	COG1815	bacterial-type flagellum-dependent cell motility
BS614_RS14985	COG1558	bacterial-type flagellum-dependent cell motility
BS614_RS14995	COG1766	The M ring may be actively involved in energy transduction
BS614_RS15000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS614_RS15010	COG1157	protein secretion by the type III secretion system
BS614_RS15015	COG2882	bacterial-type flagellum organization
BS614_RS15030	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BS614_RS15040	COG4786	Flagellar basal body rod
BS614_RS15055	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS614_RS15060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS614_RS15060	COG1776	CheC inhibitor of MCP methylation
BS614_RS15065	COG2201	protein-glutamate methylesterase activity
BS614_RS15075	COG1338	Plays a role in the flagellum-specific transport system
BS614_RS15080	COG1987	bacterial-type flagellum assembly
BS614_RS15085	COG1684	flagellar biosynthetic protein fliR
BS614_RS15090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS614_RS15095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS614_RS15100	COG1419	protein localization to endoplasmic reticulum
BS614_RS15105	COG0455	bacterial-type flagellum organization
BS614_RS15110	COG2201	protein-glutamate methylesterase activity
BS614_RS15115	COG0643	Histidine kinase
BS614_RS15115	COG2198	Histidine kinase
BS614_RS15120	COG0835	chemotaxis
BS614_RS15125	COG1776	CheC inhibitor of MCP methylation
BS614_RS15130	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BS614_RS15140	COG1191	sigma factor activity
BS614_RS15165	COG0052	Belongs to the universal ribosomal protein uS2 family
BS614_RS15170	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BS614_RS15175	COG0528	UMP kinase activity
BS614_RS15180	COG0233	cytoplasmic translational termination
BS614_RS15185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BS614_RS15190	COG4589	Belongs to the CDS family
BS614_RS15195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BS614_RS15200	COG0750	zinc metalloprotease
BS614_RS15205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS614_RS15210	COG2176	DNA-directed DNA polymerase activity
BS614_RS15215	COG0779	Required for maturation of 30S ribosomal subunits
BS614_RS15220	COG0195	Participates in both transcription termination and antitermination
BS614_RS15230	COG1358	cellular component organization or biogenesis
BS614_RS15240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BS614_RS15245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BS614_RS15250	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BS614_RS15255	COG0196	riboflavin kinase activity
BS614_RS15260	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BS614_RS15265	COG1185	polyribonucleotide nucleotidyltransferase activity
BS614_RS15270	COG0726	polysaccharide deacetylase
BS614_RS15275	COG0612	Peptidase, M16
BS614_RS15280	COG0756	dUTP diphosphatase activity
BS614_RS15285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS614_RS15290	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS614_RS15295	COG0527	aspartate kinase activity
BS614_RS15300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS614_RS15305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS614_RS15310	COG0740	serine-type endopeptidase activity
BS614_RS15330	COG0612	Peptidase, M16
BS614_RS15335	COG0612	Peptidase, M16
BS614_RS15340	COG0300	oxidoreductase activity
BS614_RS15355	COG1426	Protein conserved in bacteria
BS614_RS15365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BS614_RS15370	COG1546	Belongs to the CinA family
BS614_RS15370	COG1058	Belongs to the CinA family
BS614_RS15380	COG2137	regulation of response to DNA damage stimulus
BS614_RS15385	COG1418	mRNA catabolic process
BS614_RS15390	COG1692	metallophosphoesterase
BS614_RS15395	COG2359	stage V sporulation protein S
BS614_RS15405	COG4869	propanediol catabolic process
BS614_RS15410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS614_RS15415	COG4550	Control of competence regulator ComK, YlbF/YmcA
BS614_RS15430	COG1335	isochorismatase
BS614_RS15435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BS614_RS15445	COG0604	alcohol dehydrogenase
BS614_RS15455	COG0521	Mo-molybdopterin cofactor biosynthetic process
BS614_RS15460	COG0523	cobalamin synthesis protein
BS614_RS15470	COG0018	arginyl-trna synthetase
BS614_RS15475	COG1131	(ABC) transporter
BS614_RS15495	COG1132	(ABC) transporter
BS614_RS15500	COG1132	(ABC) transporter
BS614_RS15505	COG4841	protein insertion into membrane
BS614_RS15510	COG0494	nUDIX hydrolase
BS614_RS15520	COG2707	UPF0756 membrane protein
BS614_RS15525	COG0492	ferredoxin-NADP+ reductase activity
BS614_RS15530	COG0640	Transcriptional regulator
BS614_RS15540	COG1376	ErfK ybiS ycfS ynhG family protein
BS614_RS15565	COG1674	ftsk spoiiie
BS614_RS15600	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS15605	COG1643	Atp-dependent helicase
BS614_RS15640	COG2732	(Barnase) inhibitor
BS614_RS15655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS614_RS15660	COG3599	regulation of cell shape
BS614_RS15665	COG1959	2 iron, 2 sulfur cluster binding
BS614_RS15800	COG0456	acetyltransferase
BS614_RS15800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BS614_RS15840	COG2318	DinB family
BS614_RS15875	COG2226	methyltransferase
BS614_RS15885	COG0456	acetyltransferase
BS614_RS15910	COG4753	response regulator
BS614_RS15910	COG2207	Transcriptional regulator
BS614_RS15915	COG2972	Histidine kinase
BS614_RS15920	COG1879	ABC-type sugar transport system periplasmic component
BS614_RS15930	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS614_RS15935	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS614_RS15940	COG1879	ABC-type sugar transport system periplasmic component
BS614_RS15975	COG4106	trans-aconitate 2-methyltransferase activity
BS614_RS15990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS16000	COG0456	acetyltransferase
BS614_RS16020	COG0596	Alpha beta hydrolase
BS614_RS16050	COG2207	Transcriptional regulator
BS614_RS16050	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS16060	COG1175	transmembrane transport
BS614_RS16065	COG0395	ABC-type sugar transport system, permease component
BS614_RS16075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS614_RS16085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS614_RS16100	COG2972	Histidine kinase
BS614_RS16105	COG4753	response regulator
BS614_RS16105	COG2207	Transcriptional regulator
BS614_RS16115	COG1175	transmembrane transport
BS614_RS16120	COG0395	ABC-type sugar transport system, permease component
BS614_RS16130	COG0386	Belongs to the glutathione peroxidase family
BS614_RS16155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS614_RS16170	COG3547	Transposase (IS116 IS110 IS902 family)
BS614_RS16180	COG0109	protoheme IX farnesyltransferase activity
BS614_RS16195	COG0583	DNA-binding transcription factor activity
BS614_RS16205	COG1609	Transcriptional regulator
BS614_RS16220	COG0745	RESPONSE REGULATOR receiver
BS614_RS16225	COG5002	protein histidine kinase activity
BS614_RS16230	COG0785	Cytochrome C biogenesis protein
BS614_RS16235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS614_RS16240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS614_RS16240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS614_RS16245	COG2207	Transcriptional regulator
BS614_RS16245	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS16265	COG1902	pentaerythritol trinitrate reductase activity
BS614_RS16270	COG1349	DNA-binding transcription factor activity
BS614_RS16275	COG1764	response to oxidative stress
BS614_RS16290	COG2706	6-phosphogluconolactonase activity
BS614_RS16300	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BS614_RS16305	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BS614_RS16310	COG1733	regulation of RNA biosynthetic process
BS614_RS16315	COG1164	Oligoendopeptidase f
BS614_RS16325	COG1070	Carbohydrate kinase
BS614_RS16330	COG1349	DNA-binding transcription factor activity
BS614_RS16345	COG1556	Lactate utilization protein
BS614_RS16350	COG0386	Belongs to the glutathione peroxidase family
BS614_RS16375	COG0673	inositol 2-dehydrogenase activity
BS614_RS16380	COG2207	Transcriptional regulator
BS614_RS16410	COG2176	DNA-directed DNA polymerase activity
BS614_RS16430	COG2207	Transcriptional regulator
BS614_RS16430	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS16445	COG2801	Transposase and inactivated derivatives
BS614_RS16460	COG2207	Transcriptional regulator
BS614_RS16465	COG2972	Histidine kinase
BS614_RS16470	COG4608	Belongs to the ABC transporter superfamily
BS614_RS16475	COG0444	Belongs to the ABC transporter superfamily
BS614_RS16480	COG0601	transmembrane transport
BS614_RS16485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS614_RS16490	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS16495	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS16505	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS16515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BS614_RS16515	COG0574	Belongs to the PEP-utilizing enzyme family
BS614_RS16520	COG1368	sulfuric ester hydrolase activity
BS614_RS16525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS614_RS16530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BS614_RS16535	COG1227	inorganic diphosphatase activity
BS614_RS16540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BS614_RS16550	COG5002	protein histidine kinase activity
BS614_RS16550	COG2198	Histidine kinase
BS614_RS16550	COG0784	Response regulator, receiver
BS614_RS16555	COG0490	domain, Protein
BS614_RS16570	COG1454	alcohol dehydrogenase
BS614_RS16590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS614_RS16595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS614_RS16600	COG0058	SHG alpha-glucan phosphorylase activity
BS614_RS16615	COG0366	Alpha amylase catalytic
BS614_RS16620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BS614_RS16630	COG0366	Alpha amylase catalytic
BS614_RS16635	COG1263	PTS System
BS614_RS16635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS16655	COG3180	Ammonia monooxygenase
BS614_RS16665	COG4122	O-methyltransferase activity
BS614_RS16675	COG3619	membrane
BS614_RS16680	COG1506	peptidase
BS614_RS16685	COG2357	RelA SpoT domain protein
BS614_RS16690	COG2814	Major facilitator Superfamily
BS614_RS16705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS614_RS16720	COG1073	alpha beta
BS614_RS16725	COG2755	lipolytic protein G-D-S-L family
BS614_RS16725	COG3401	FG-GAP repeat protein
BS614_RS16730	COG1320	monovalent cation:proton antiporter activity
BS614_RS16735	COG2212	antiporter activity
BS614_RS16740	COG1863	multisubunit Na H antiporter MnhE subunit
BS614_RS16745	COG0651	ATP synthesis coupled electron transport
BS614_RS16750	COG1006	Multisubunit Na H antiporter MnhC subunit
BS614_RS16755	COG2111	Na H antiporter
BS614_RS16755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS614_RS16795	COG1528	Iron-storage protein
BS614_RS16800	COG0726	polysaccharide deacetylase
BS614_RS16810	COG2197	response regulator
BS614_RS16815	COG4585	Histidine kinase
BS614_RS16820	COG3239	Fatty acid desaturase
BS614_RS16825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS614_RS16830	COG1940	carbohydrate kinase activity
BS614_RS16835	COG1940	carbohydrate kinase activity
BS614_RS16845	COG2207	Transcriptional regulator
BS614_RS16860	COG4209	transmembrane transport
BS614_RS16865	COG0395	ABC-type sugar transport system, permease component
BS614_RS16885	COG1695	Transcriptional regulator
BS614_RS16895	COG4166	transmembrane transport
BS614_RS16915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS614_RS16920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS614_RS16945	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS16955	COG3693	PFAM glycoside hydrolase, family 10
BS614_RS16960	COG1136	(ABC) transporter
BS614_RS16960	COG0577	efflux transmembrane transporter activity
BS614_RS16970	COG5002	protein histidine kinase activity
BS614_RS16990	COG2814	Major facilitator Superfamily
BS614_RS16995	COG1309	transcriptional regulator
BS614_RS17000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BS614_RS17005	COG1609	Transcriptional regulator
BS614_RS17010	COG1063	alcohol dehydrogenase
BS614_RS17025	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS17030	COG0745	RESPONSE REGULATOR receiver
BS614_RS17035	COG2205	protein histidine kinase activity
BS614_RS17040	COG1136	(ABC) transporter
BS614_RS17045	COG0577	efflux transmembrane transporter activity
BS614_RS17050	COG2368	4-hydroxyphenylacetate
BS614_RS17065	COG0628	permease
BS614_RS17080	COG0667	Aldo Keto reductase
BS614_RS17085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS614_RS17095	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BS614_RS17105	COG0778	Nitroreductase
BS614_RS17115	COG1876	peptidase activity
BS614_RS17125	COG0517	IMP dehydrogenase activity
BS614_RS17125	COG1125	glycine betaine transport
BS614_RS17135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS614_RS17155	COG3693	PFAM glycoside hydrolase, family 10
BS614_RS17160	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BS614_RS17165	COG1733	regulation of RNA biosynthetic process
BS614_RS17170	COG2801	Transposase and inactivated derivatives
BS614_RS17180	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BS614_RS17185	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS614_RS17220	COG2409	Drug exporters of the RND superfamily
BS614_RS17220	COG1033	growth of symbiont in host cell
BS614_RS17240	COG1201	RNA secondary structure unwinding
BS614_RS17265	COG2188	Transcriptional regulator
BS614_RS17270	COG0457	Tetratricopeptide repeat
BS614_RS17285	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS17285	COG3347	Dehydrogenase
BS614_RS17290	COG4806	L-rhamnose isomerase
BS614_RS17295	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS614_RS17300	COG1609	Transcriptional regulator
BS614_RS17305	COG1621	beta-fructofuranosidase activity
BS614_RS17325	COG3618	amidohydrolase
BS614_RS17330	COG2723	6-phospho-beta-galactosidase activity
BS614_RS17335	COG3711	transcriptional antiterminator
BS614_RS17350	COG1268	BioY protein
BS614_RS17355	COG1122	ATPase activity
BS614_RS17370	COG1051	belongs to the nudix hydrolase family
BS614_RS17390	COG0789	Transcriptional regulator
BS614_RS17405	COG3850	Histidine kinase
BS614_RS17405	COG5002	protein histidine kinase activity
BS614_RS17410	COG0745	RESPONSE REGULATOR receiver
BS614_RS17415	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BS614_RS17420	COG0463	Glycosyl transferase, family 2
BS614_RS17430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS614_RS17435	COG2226	methyltransferase
BS614_RS17450	COG0656	L-ascorbic acid biosynthetic process
BS614_RS17455	COG0385	Bile acid
BS614_RS17465	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS17470	COG0730	response to heat
BS614_RS17480	COG0784	Response regulator, receiver
BS614_RS17480	COG2198	Histidine kinase
BS614_RS17480	COG2205	protein histidine kinase activity
BS614_RS17485	COG4533	DNA binding
BS614_RS17490	COG2211	Major facilitator Superfamily
BS614_RS17495	COG1132	(ABC) transporter
BS614_RS17500	COG1132	(ABC) transporter
BS614_RS17505	COG0109	protoheme IX farnesyltransferase activity
BS614_RS17510	COG0492	ferredoxin-NADP+ reductase activity
BS614_RS17515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BS614_RS17515	COG2124	cytochrome p450
BS614_RS17520	COG1309	transcriptional regulator
BS614_RS17525	COG0477	Major facilitator Superfamily
BS614_RS17535	COG0596	Alpha beta hydrolase
BS614_RS17550	COG1396	sequence-specific DNA binding
BS614_RS17555	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS17570	COG0753	catalase activity
BS614_RS17580	COG2814	Major facilitator Superfamily
BS614_RS17595	COG1609	Transcriptional regulator
BS614_RS17600	COG2814	Major facilitator Superfamily
BS614_RS17605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS614_RS17610	COG1609	Transcriptional regulator
BS614_RS17615	COG4209	transmembrane transport
BS614_RS17620	COG0395	ABC-type sugar transport system, permease component
BS614_RS17660	COG3394	polysaccharide catabolic process
BS614_RS17670	COG1404	Belongs to the peptidase S8 family
BS614_RS17670	COG4412	M6 family metalloprotease domain protein
BS614_RS17675	COG1609	Transcriptional regulator
BS614_RS17690	COG1175	transmembrane transport
BS614_RS17695	COG3833	ABC-type maltose transport systems, permease component
BS614_RS17700	COG0383	alpha-mannosidase activity
BS614_RS17735	COG0673	inositol 2-dehydrogenase activity
BS614_RS17745	COG0673	inositol 2-dehydrogenase activity
BS614_RS17755	COG1473	amidohydrolase
BS614_RS17770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS614_RS17775	COG4946	Tricorn protease homolog
BS614_RS17775	COG1506	peptidase
BS614_RS17775	COG0823	Involved in the tonB-independent uptake of proteins
BS614_RS17830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS614_RS17835	COG1063	alcohol dehydrogenase
BS614_RS17850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS614_RS17855	COG2207	Transcriptional regulator
BS614_RS17860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS614_RS17875	COG2814	Major facilitator Superfamily
BS614_RS17880	COG1309	transcriptional regulator
BS614_RS17885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS17895	COG5002	protein histidine kinase activity
BS614_RS17910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS614_RS17915	COG2814	Major facilitator Superfamily
BS614_RS17940	COG1132	(ABC) transporter
BS614_RS17945	COG1846	Transcriptional regulator
BS614_RS17945	COG0456	acetyltransferase
BS614_RS17955	COG2207	Transcriptional regulator
BS614_RS17960	COG0667	Aldo Keto reductase
BS614_RS17975	COG2076	Multidrug Resistance protein
BS614_RS17980	COG2076	Multidrug Resistance protein
BS614_RS17985	COG0513	Belongs to the DEAD box helicase family
BS614_RS17990	COG2315	Protein conserved in bacteria
BS614_RS18020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS614_RS18025	COG2030	dehydratase
BS614_RS18035	COG4977	sequence-specific DNA binding
BS614_RS18050	COG0395	ABC-type sugar transport system, permease component
BS614_RS18055	COG0697	spore germination
BS614_RS18085	COG2198	Histidine kinase
BS614_RS18085	COG0784	Response regulator, receiver
BS614_RS18085	COG2205	protein histidine kinase activity
BS614_RS18095	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BS614_RS18105	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS18110	COG3250	beta-galactosidase activity
BS614_RS18130	COG3279	Response regulator of the LytR AlgR family
BS614_RS18150	COG4106	trans-aconitate 2-methyltransferase activity
BS614_RS18180	COG3739	integral membrane protein
BS614_RS18185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS614_RS18210	COG1131	(ABC) transporter
BS614_RS18215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS614_RS18220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS614_RS18235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS614_RS18245	COG1733	regulation of RNA biosynthetic process
BS614_RS18265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS18275	COG0702	epimerase
BS614_RS18290	COG2207	Transcriptional regulator
BS614_RS18295	COG1309	transcriptional regulator
BS614_RS18300	COG0789	Transcriptional regulator
BS614_RS18305	COG1064	alcohol dehydrogenase
BS614_RS18310	COG0537	adenosine 5'-monophosphoramidase activity
BS614_RS18320	COG5646	InterPro IPR014922
BS614_RS18325	COG0667	Aldo Keto reductase
BS614_RS18335	COG1733	regulation of RNA biosynthetic process
BS614_RS18340	COG3973	AAA domain
BS614_RS18345	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS18350	COG0395	ABC-type sugar transport system, permease component
BS614_RS18355	COG1175	transmembrane transport
BS614_RS18360	COG1653	transport
BS614_RS18365	COG2972	Histidine kinase
BS614_RS18370	COG2207	Transcriptional regulator
BS614_RS18370	COG4753	response regulator
BS614_RS18375	COG0840	transmembrane signaling receptor activity
BS614_RS18380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BS614_RS18385	COG2409	Drug exporters of the RND superfamily
BS614_RS18400	COG2124	cytochrome p450
BS614_RS18415	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS18425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS614_RS18460	COG1609	Transcriptional regulator
BS614_RS18465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS614_RS18475	COG1129	ABC transporter
BS614_RS18480	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS614_RS18485	COG1879	ABC-type sugar transport system periplasmic component
BS614_RS18495	COG3135	benzoate transporter
BS614_RS18505	COG0702	epimerase
BS614_RS18510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS614_RS18515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS614_RS18520	COG0765	amino acid transport
BS614_RS18525	COG1126	abc transporter atp-binding protein
BS614_RS18540	COG2207	Transcriptional regulator
BS614_RS18575	COG2207	Transcriptional regulator
BS614_RS18580	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS18590	COG1653	transport
BS614_RS18595	COG2972	Histidine kinase
BS614_RS18600	COG4753	response regulator
BS614_RS18600	COG2207	Transcriptional regulator
BS614_RS18605	COG4977	sequence-specific DNA binding
BS614_RS18605	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS18620	COG1175	transmembrane transport
BS614_RS18625	COG0395	ABC-type sugar transport system, permease component
BS614_RS18645	COG1175	transmembrane transport
BS614_RS18650	COG0395	ABC-type sugar transport system, permease component
BS614_RS18665	COG4209	transmembrane transport
BS614_RS18670	COG0395	ABC-type sugar transport system, permease component
BS614_RS18675	COG1653	transport
BS614_RS18690	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS18690	COG3693	PFAM glycoside hydrolase, family 10
BS614_RS18690	COG2382	esterase
BS614_RS18705	COG2207	Transcriptional regulator
BS614_RS18710	COG2972	Histidine kinase
BS614_RS18715	COG4753	response regulator
BS614_RS18715	COG2207	Transcriptional regulator
BS614_RS18725	COG4209	transmembrane transport
BS614_RS18730	COG0395	ABC-type sugar transport system, permease component
BS614_RS18740	COG1776	CheC inhibitor of MCP methylation
BS614_RS18755	COG1733	regulation of RNA biosynthetic process
BS614_RS18775	COG1846	Transcriptional regulator
BS614_RS18795	COG4753	response regulator
BS614_RS18795	COG2207	Transcriptional regulator
BS614_RS18795	COG4753	response regulator
BS614_RS18795	COG2207	Transcriptional regulator
BS614_RS18800	COG2972	Histidine kinase
BS614_RS18815	COG4209	transmembrane transport
BS614_RS18820	COG0395	ABC-type sugar transport system, permease component
BS614_RS18825	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS18835	COG2814	Major facilitator Superfamily
BS614_RS18865	COG0583	DNA-binding transcription factor activity
BS614_RS18870	COG0477	Major facilitator Superfamily
BS614_RS18875	COG1271	oxidase subunit
BS614_RS18880	COG1294	oxidase, subunit
BS614_RS18885	COG1132	(ABC) transporter
BS614_RS18890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BS614_RS18900	COG4753	response regulator
BS614_RS18900	COG2207	Transcriptional regulator
BS614_RS18905	COG2972	Histidine kinase
BS614_RS18910	COG0395	ABC-type sugar transport system, permease component
BS614_RS18915	COG4209	transmembrane transport
BS614_RS18925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BS614_RS18930	COG0583	DNA-binding transcription factor activity
BS614_RS18940	COG1733	regulation of RNA biosynthetic process
BS614_RS18970	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS18970	COG2207	Transcriptional regulator
BS614_RS18975	COG1486	melibiose metabolic process
BS614_RS18990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS614_RS19000	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS614_RS19005	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS19010	COG0531	amino acid
BS614_RS19025	COG1733	regulation of RNA biosynthetic process
BS614_RS19030	COG1174	glycine betaine transport
BS614_RS19045	COG1174	glycine betaine transport
BS614_RS19050	COG0604	alcohol dehydrogenase
BS614_RS19050	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS19050	COG3321	synthase
BS614_RS19060	COG0024	Methionine aminopeptidase
BS614_RS19065	COG2311	Membrane
BS614_RS19070	COG2318	DinB family
BS614_RS19090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BS614_RS19095	COG0640	Transcriptional regulator
BS614_RS19100	COG0656	L-ascorbic acid biosynthetic process
BS614_RS19110	COG0592	DNA-directed DNA polymerase activity
BS614_RS19115	COG2207	Transcriptional regulator
BS614_RS19115	COG3708	Transcriptional regulator
BS614_RS19125	COG2204	response regulator
BS614_RS19130	COG2972	Histidine kinase
BS614_RS19135	COG4209	transmembrane transport
BS614_RS19140	COG0395	ABC-type sugar transport system, permease component
BS614_RS19145	COG1653	transport
BS614_RS19165	COG1199	ATP-dependent helicase activity
BS614_RS19195	COG0662	Cupin 2, conserved barrel domain protein
BS614_RS19200	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS19200	COG2207	Transcriptional regulator
BS614_RS19210	COG0745	RESPONSE REGULATOR receiver
BS614_RS19220	COG0666	response to abiotic stimulus
BS614_RS19225	COG2273	Hydrolase Family 16
BS614_RS19230	COG1653	transport
BS614_RS19240	COG2972	Histidine kinase
BS614_RS19245	COG4209	transmembrane transport
BS614_RS19250	COG0395	ABC-type sugar transport system, permease component
BS614_RS19275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS19295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS614_RS19300	COG0697	spore germination
BS614_RS19305	COG4977	sequence-specific DNA binding
BS614_RS19305	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS19320	COG2814	Major facilitator Superfamily
BS614_RS19325	COG1733	regulation of RNA biosynthetic process
BS614_RS19330	COG0316	Belongs to the HesB IscA family
BS614_RS19345	COG1819	glycosyl
BS614_RS19350	COG2814	Major facilitator Superfamily
BS614_RS19365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS614_RS19375	COG0531	amino acid
BS614_RS19380	COG0697	spore germination
BS614_RS19395	COG2814	Major facilitator Superfamily
BS614_RS19400	COG0583	DNA-binding transcription factor activity
BS614_RS19405	COG0534	Mate efflux family protein
BS614_RS19410	COG4209	transmembrane transport
BS614_RS19415	COG0395	ABC-type sugar transport system, permease component
BS614_RS19420	COG1653	transport
BS614_RS19425	COG3275	phosphorelay sensor kinase activity
BS614_RS19455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS614_RS19485	COG2207	Transcriptional regulator
BS614_RS19490	COG1785	Belongs to the alkaline phosphatase family
BS614_RS19505	COG0446	pyridine nucleotide-disulphide oxidoreductase
BS614_RS19510	COG0640	Transcriptional regulator
BS614_RS19515	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS614_RS19520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS614_RS19525	COG0789	Transcriptional regulator
BS614_RS19525	COG4978	Transcriptional regulator
BS614_RS19530	COG2814	Major facilitator Superfamily
BS614_RS19540	COG1309	transcriptional regulator
BS614_RS19545	COG2084	Dehydrogenase
BS614_RS19555	COG0657	acetylesterase activity
BS614_RS19575	COG0129	dihydroxy-acid dehydratase activity
BS614_RS19580	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS19615	COG2207	Transcriptional regulator
BS614_RS19620	COG3401	FG-GAP repeat protein
BS614_RS19625	COG3275	phosphorelay sensor kinase activity
BS614_RS19630	COG4753	response regulator
BS614_RS19630	COG2207	Transcriptional regulator
BS614_RS19640	COG4209	transmembrane transport
BS614_RS19645	COG0395	ABC-type sugar transport system, permease component
BS614_RS19650	COG0366	Alpha amylase catalytic
BS614_RS19655	COG0366	Alpha amylase catalytic
BS614_RS19670	COG0840	transmembrane signaling receptor activity
BS614_RS19675	COG2267	carboxylic ester hydrolase activity
BS614_RS19680	COG0583	DNA-binding transcription factor activity
BS614_RS19690	COG0488	(ABC) transporter
BS614_RS19700	COG1263	PTS System
BS614_RS19700	COG2190	(PTS) system
BS614_RS19700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS19705	COG2723	6-phospho-beta-galactosidase activity
BS614_RS19710	COG3711	transcriptional antiterminator
BS614_RS19750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS614_RS19760	COG2801	Transposase and inactivated derivatives
BS614_RS19770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BS614_RS19780	COG2508	Transcriptional regulator
BS614_RS19785	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS19790	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS19795	COG4209	transmembrane transport
BS614_RS19800	COG0395	ABC-type sugar transport system, permease component
BS614_RS19805	COG1653	transport
BS614_RS19820	COG1846	Transcriptional regulator
BS614_RS19835	COG2169	Transcriptional regulator
BS614_RS19840	COG0534	Mate efflux family protein
BS614_RS19845	COG0110	maltose O-acetyltransferase activity
BS614_RS19850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BS614_RS19855	COG1846	Transcriptional regulator
BS614_RS19860	COG0778	Nitroreductase
BS614_RS19865	COG0604	alcohol dehydrogenase
BS614_RS19900	COG0745	RESPONSE REGULATOR receiver
BS614_RS19905	COG5002	protein histidine kinase activity
BS614_RS19945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BS614_RS19950	COG0583	DNA-binding transcription factor activity
BS614_RS19960	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BS614_RS19975	COG2217	Heavy metal translocating P-type atpase
BS614_RS20005	COG2070	2-Nitropropane dioxygenase
BS614_RS20005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BS614_RS20010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS614_RS20015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS614_RS20015	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS20015	COG3321	synthase
BS614_RS20015	COG4221	oxidoreductase activity
BS614_RS20020	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS20020	COG3321	synthase
BS614_RS20020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS614_RS20020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS614_RS20020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS614_RS20025	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS20025	COG3321	synthase
BS614_RS20025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS614_RS20025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS614_RS20025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS614_RS20030	COG3321	synthase
BS614_RS20030	COG0300	oxidoreductase activity
BS614_RS20030	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS20030	COG0318	PFAM AMP-dependent synthetase and ligase
BS614_RS20030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS614_RS20035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS614_RS20035	COG0300	oxidoreductase activity
BS614_RS20035	COG3321	synthase
BS614_RS20035	COG4221	oxidoreductase activity
BS614_RS20035	COG3321	synthase
BS614_RS20035	COG0300	oxidoreductase activity
BS614_RS20035	COG4221	oxidoreductase activity
BS614_RS20035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS614_RS20040	COG1755	Isoprenylcysteine carboxyl methyltransferase
BS614_RS20045	COG2124	cytochrome p450
BS614_RS20055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS614_RS20090	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS20105	COG3275	phosphorelay sensor kinase activity
BS614_RS20110	COG4753	response regulator
BS614_RS20110	COG2207	Transcriptional regulator
BS614_RS20125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS20155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS614_RS20165	COG2207	Transcriptional regulator
BS614_RS20165	COG4753	response regulator
BS614_RS20170	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS20175	COG4585	Histidine kinase
BS614_RS20180	COG2197	response regulator
BS614_RS20185	COG2409	Drug exporters of the RND superfamily
BS614_RS20200	COG2972	Histidine kinase
BS614_RS20205	COG1653	transport
BS614_RS20215	COG3408	Glycogen debranching enzyme
BS614_RS20220	COG2124	cytochrome p450
BS614_RS20225	COG2211	Major facilitator Superfamily
BS614_RS20240	COG0515	serine threonine protein kinase
BS614_RS20240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BS614_RS20250	COG0156	8-amino-7-oxononanoate synthase activity
BS614_RS20255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS614_RS20260	COG0300	oxidoreductase activity
BS614_RS20280	COG1609	Transcriptional regulator
BS614_RS20285	COG1653	transport
BS614_RS20290	COG1175	transmembrane transport
BS614_RS20295	COG0395	ABC-type sugar transport system, permease component
BS614_RS20300	COG3940	Belongs to the glycosyl hydrolase 43 family
BS614_RS20315	COG1714	RDD family
BS614_RS20325	COG4607	ABC-type enterochelin transport system periplasmic component
BS614_RS20330	COG1132	(ABC) transporter
BS614_RS20330	COG2375	cellular response to nickel ion
BS614_RS20365	COG3831	ATPase activity
BS614_RS20370	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BS614_RS20380	COG0714	Associated with various cellular activities
BS614_RS20385	COG4989	oxidoreductase activity
BS614_RS20390	COG2124	cytochrome p450
BS614_RS20405	COG0028	Belongs to the TPP enzyme family
BS614_RS20410	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS20420	COG0254	rRNA binding
BS614_RS20430	COG1063	alcohol dehydrogenase
BS614_RS20445	COG2207	Transcriptional regulator
BS614_RS20450	COG1012	belongs to the aldehyde dehydrogenase family
BS614_RS20460	COG1802	Transcriptional regulator
BS614_RS20465	COG1312	Catalyzes the dehydration of D-mannonate
BS614_RS20470	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS20475	COG2323	membrane
BS614_RS20500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS614_RS20505	COG1121	(ABC) transporter
BS614_RS20520	COG0523	cobalamin synthesis protein
BS614_RS20525	COG0701	Predicted permease
BS614_RS20535	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BS614_RS20550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS614_RS20555	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BS614_RS20560	COG2390	Transcriptional regulator
BS614_RS20575	COG2814	Major facilitator Superfamily
BS614_RS20585	COG1177	transmembrane transport
BS614_RS20590	COG4149	molybdate abc transporter
BS614_RS20595	COG3842	ATPase activity
BS614_RS20600	COG1653	transport
BS614_RS20625	COG1070	Carbohydrate kinase
BS614_RS20630	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
BS614_RS20635	COG1609	Transcriptional regulator
BS614_RS20650	COG0673	inositol 2-dehydrogenase activity
BS614_RS20655	COG2169	Transcriptional regulator
BS614_RS20665	COG0673	inositol 2-dehydrogenase activity
BS614_RS20675	COG0673	inositol 2-dehydrogenase activity
BS614_RS20680	COG1609	Transcriptional regulator
BS614_RS20685	COG1494	fructose-1,6-bisphosphatase
BS614_RS20690	COG1132	(ABC) transporter
BS614_RS20710	COG2192	nodulation
BS614_RS20715	COG2192	nodulation
BS614_RS20730	COG0456	acetyltransferase
BS614_RS20740	COG2080	2 iron, 2 sulfur cluster binding
BS614_RS20745	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BS614_RS20755	COG2068	MobA-Related Protein
BS614_RS20760	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BS614_RS20765	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS20770	COG0405	Gamma-glutamyltransferase
BS614_RS20775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BS614_RS20780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS614_RS20785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BS614_RS20790	COG2351	hydroxyisourate hydrolase activity
BS614_RS20795	COG3195	allantoin biosynthetic process
BS614_RS20795	COG3648	Uricase
BS614_RS20800	COG2508	Transcriptional regulator
BS614_RS20805	COG0784	Response regulator, receiver
BS614_RS20805	COG2205	protein histidine kinase activity
BS614_RS20810	COG0114	fumarate hydratase activity
BS614_RS20820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS614_RS20830	COG2309	aminopeptidase activity
BS614_RS20835	COG2309	aminopeptidase activity
BS614_RS20840	COG1595	DNA-templated transcription, initiation
BS614_RS20860	COG1253	flavin adenine dinucleotide binding
BS614_RS20875	COG3773	Cell wall hydrolase
BS614_RS20885	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS20915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS614_RS20945	COG0039	L-malate dehydrogenase activity
BS614_RS20950	COG4974	Belongs to the 'phage' integrase family
BS614_RS20960	COG0531	amino acid
BS614_RS20965	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS20990	COG3665	Urea carboxylase-associated protein
BS614_RS20995	COG1280	lysine exporter protein (LysE YggA)
BS614_RS21000	COG3403	YqcI/YcgG family
BS614_RS21005	COG1113	amino acid transport
BS614_RS21010	COG0667	Aldo Keto reductase
BS614_RS21015	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS21025	COG4974	Belongs to the 'phage' integrase family
BS614_RS21035	COG0303	'Molybdopterin
BS614_RS21040	COG1403	HNH endonuclease
BS614_RS21060	COG1842	Phage shock protein A
BS614_RS21075	COG3584	3D domain protein
BS614_RS21075	COG1388	LysM domain
BS614_RS21080	COG1126	abc transporter atp-binding protein
BS614_RS21085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS614_RS21100	COG0297	glycogen (starch) synthase activity
BS614_RS21105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BS614_RS21110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS614_RS21115	COG5002	protein histidine kinase activity
BS614_RS21120	COG0745	RESPONSE REGULATOR receiver
BS614_RS21135	COG0477	Major facilitator Superfamily
BS614_RS21155	COG0735	belongs to the Fur family
BS614_RS21160	COG0493	'glutamate synthase
BS614_RS21165	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS614_RS21170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BS614_RS21180	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS614_RS21185	COG0022	dehydrogenase e1 component
BS614_RS21200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS614_RS21205	COG2860	membrane
BS614_RS21210	COG1564	THIamine pyrophosphokinase
BS614_RS21220	COG0745	RESPONSE REGULATOR receiver
BS614_RS21225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS614_RS21230	COG2022	thiamine diphosphate biosynthetic process
BS614_RS21240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS614_RS21245	COG0352	thiamine-phosphate diphosphorylase activity
BS614_RS21250	COG0488	(ABC) transporter
BS614_RS21300	COG0515	serine threonine protein kinase
BS614_RS21305	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BS614_RS21310	COG1119	ATPase activity
BS614_RS21315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS614_RS21325	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BS614_RS21335	COG0647	UMP catabolic process
BS614_RS21340	COG1234	tRNA 3'-trailer cleavage
BS614_RS21345	COG1410	methionine synthase
BS614_RS21345	COG0646	methionine synthase
BS614_RS21350	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BS614_RS21355	COG1802	Transcriptional regulator
BS614_RS21365	COG0395	ABC-type sugar transport system, permease component
BS614_RS21370	COG4209	transmembrane transport
BS614_RS21375	COG1011	Hydrolase
BS614_RS21385	COG4224	UPF0291 protein
BS614_RS21395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BS614_RS21400	COG1012	belongs to the aldehyde dehydrogenase family
BS614_RS21435	COG0174	glutamine synthetase
BS614_RS21440	COG0789	Transcriptional regulator
BS614_RS21445	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BS614_RS21450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BS614_RS21455	COG0464	growth
BS614_RS21465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS614_RS21470	COG1923	regulation of RNA biosynthetic process
BS614_RS21475	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BS614_RS21480	COG2136	Putative SAM-dependent methyltransferase
BS614_RS21480	COG2521	methyltransferase
BS614_RS21485	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BS614_RS21490	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BS614_RS21505	COG4129	membrane
BS614_RS21510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS614_RS21515	COG1116	anion transmembrane transporter activity
BS614_RS21520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS614_RS21525	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BS614_RS21530	COG0288	reversible hydration of carbon dioxide
BS614_RS21565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BS614_RS21570	COG2233	PERMEase
BS614_RS21595	COG2207	Transcriptional regulator
BS614_RS21595	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS21600	COG0697	spore germination
BS614_RS21605	COG1187	pseudouridine synthase activity
BS614_RS21620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BS614_RS21625	COG1063	alcohol dehydrogenase
BS614_RS21630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS614_RS21645	COG0561	phosphatase activity
BS614_RS21650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS614_RS21690	COG0561	phosphatase activity
BS614_RS21710	COG2723	6-phospho-beta-galactosidase activity
BS614_RS21715	COG1263	PTS System
BS614_RS21715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS21715	COG2190	(PTS) system
BS614_RS21720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS21720	COG1263	PTS System
BS614_RS21720	COG2190	(PTS) system
BS614_RS21725	COG3711	transcriptional antiterminator
BS614_RS21755	COG3408	Glycogen debranching enzyme
BS614_RS21770	COG2723	6-phospho-beta-galactosidase activity
BS614_RS21775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS21775	COG2190	(PTS) system
BS614_RS21775	COG1263	PTS System
BS614_RS21780	COG3711	transcriptional antiterminator
BS614_RS21790	COG1408	metallophosphoesterase
BS614_RS21795	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BS614_RS21805	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BS614_RS21810	COG0583	DNA-binding transcription factor activity
BS614_RS21815	COG0643	Histidine kinase
BS614_RS21815	COG2198	Histidine kinase
BS614_RS21840	COG0667	Aldo Keto reductase
BS614_RS21860	COG3459	Glycosyltransferase 36 associated
BS614_RS21910	COG5577	PFAM Coat F domain
BS614_RS21925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS614_RS22005	COG0577	efflux transmembrane transporter activity
BS614_RS22010	COG1136	(ABC) transporter
BS614_RS22015	COG2205	protein histidine kinase activity
BS614_RS22020	COG0745	RESPONSE REGULATOR receiver
BS614_RS22045	COG0745	RESPONSE REGULATOR receiver
BS614_RS22050	COG5002	protein histidine kinase activity
BS614_RS22055	COG0464	growth
BS614_RS22065	COG2368	4-hydroxyphenylacetate
BS614_RS22080	COG0716	FMN binding
BS614_RS22085	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BS614_RS22085	COG0116	Belongs to the methyltransferase superfamily
BS614_RS22090	COG0564	pseudouridine synthase activity
BS614_RS22095	COG3695	enzyme binding
BS614_RS22100	COG2814	Major facilitator Superfamily
BS614_RS22110	COG1846	Transcriptional regulator
BS614_RS22115	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS614_RS22130	COG1131	(ABC) transporter
BS614_RS22140	COG2340	Cysteine-rich secretory protein family
BS614_RS22150	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BS614_RS22155	COG0492	ferredoxin-NADP+ reductase activity
BS614_RS22160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS22165	COG2207	Transcriptional regulator
BS614_RS22170	COG1132	(ABC) transporter
BS614_RS22175	COG1132	(ABC) transporter
BS614_RS22180	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS614_RS22190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BS614_RS22205	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS614_RS22210	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS614_RS22215	COG0066	3-isopropylmalate dehydratase activity
BS614_RS22220	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BS614_RS22225	COG2723	6-phospho-beta-galactosidase activity
BS614_RS22230	COG3711	transcriptional antiterminator
BS614_RS22235	COG1263	PTS System
BS614_RS22235	COG2190	(PTS) system
BS614_RS22235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS22240	COG0583	DNA-binding transcription factor activity
BS614_RS22245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS614_RS22250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BS614_RS22255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS22260	COG0436	Aminotransferase
BS614_RS22265	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BS614_RS22270	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BS614_RS22275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS614_RS22280	COG1850	ribulose-bisphosphate carboxylase activity
BS614_RS22285	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BS614_RS22290	COG0235	Class ii aldolase
BS614_RS22305	COG1595	DNA-templated transcription, initiation
BS614_RS22310	COG3935	DnaD domain protein
BS614_RS22315	COG0017	Asparaginyl-tRNA synthetase
BS614_RS22320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BS614_RS22325	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS614_RS22330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS614_RS22345	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS22350	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BS614_RS22355	COG1199	ATP-dependent helicase activity
BS614_RS22355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BS614_RS22365	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BS614_RS22370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BS614_RS22375	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BS614_RS22385	COG0617	tRNA 3'-terminal CCA addition
BS614_RS22390	COG0438	transferase activity, transferring glycosyl groups
BS614_RS22395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS614_RS22400	COG1803	Methylglyoxal synthase
BS614_RS22405	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BS614_RS22415	COG1694	Mazg nucleotide pyrophosphohydrolase
BS614_RS22420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS614_RS22435	COG4347	Protein of unknown function (DUF1405)
BS614_RS22465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BS614_RS22475	COG0406	alpha-ribazole phosphatase activity
BS614_RS22490	COG0287	Prephenate dehydrogenase
BS614_RS22495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BS614_RS22500	COG0159	tryptophan synthase activity
BS614_RS22505	COG0133	tryptophan synthase activity
BS614_RS22510	COG0135	phosphoribosylanthranilate isomerase activity
BS614_RS22515	COG0134	indole-3-glycerol-phosphate synthase activity
BS614_RS22520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BS614_RS22530	COG4401	Chorismate mutase type I
BS614_RS22535	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BS614_RS22540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BS614_RS22545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BS614_RS22550	COG0105	UTP biosynthetic process
BS614_RS22560	COG0163	prenyltransferase activity
BS614_RS22565	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BS614_RS22570	COG2226	methyltransferase
BS614_RS22590	COG0776	regulation of translation
BS614_RS22600	COG1129	ABC transporter
BS614_RS22610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS614_RS22645	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BS614_RS22650	COG1160	GTP binding
BS614_RS22655	COG0539	negative regulation of cytoplasmic translation
BS614_RS22660	COG0204	Acyl-transferase
BS614_RS22665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BS614_RS22680	COG2959	enzyme of heme biosynthesis
BS614_RS22685	COG2339	peptidase activity
BS614_RS22690	COG4862	establishment of competence for transformation
BS614_RS22700	COG0726	polysaccharide deacetylase
BS614_RS22705	COG1408	metallophosphoesterase
BS614_RS22720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BS614_RS22730	COG2801	Transposase and inactivated derivatives
BS614_RS22740	COG5002	protein histidine kinase activity
BS614_RS22740	COG5002	protein histidine kinase activity
BS614_RS22745	COG0745	RESPONSE REGULATOR receiver
BS614_RS22750	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS614_RS22755	COG1333	cytochrome c biogenesis protein
BS614_RS22760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS614_RS22765	COG1187	pseudouridine synthase activity
BS614_RS22775	COG0700	Nucleoside recognition
BS614_RS22780	COG2715	membrane protein required for spore maturation
BS614_RS22785	COG1686	Belongs to the peptidase S11 family
BS614_RS22790	COG3874	Sporulation protein YtfJ
BS614_RS22800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BS614_RS22805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BS614_RS22810	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BS614_RS22815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS614_RS22815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS614_RS22825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS614_RS22825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS614_RS22835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS614_RS22840	COG0019	diaminopimelate decarboxylase activity
BS614_RS22845	COG0697	spore germination
BS614_RS22860	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS22860	COG2207	Transcriptional regulator
BS614_RS22875	COG2172	sigma factor antagonist activity
BS614_RS22880	COG1366	Belongs to the anti-sigma-factor antagonist family
BS614_RS22885	COG1686	Belongs to the peptidase S11 family
BS614_RS22895	COG4974	Belongs to the 'phage' integrase family
BS614_RS22905	COG0735	belongs to the Fur family
BS614_RS22910	COG1300	Membrane
BS614_RS22915	COG1379	DNA repair
BS614_RS22920	COG0494	nUDIX hydrolase
BS614_RS22925	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS614_RS22930	COG0321	lipoyl(octanoyl) transferase activity
BS614_RS22935	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS614_RS22940	COG0022	dehydrogenase e1 component
BS614_RS22945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS614_RS22950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS614_RS22990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS22995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS23010	COG0745	RESPONSE REGULATOR receiver
BS614_RS23015	COG0750	zinc metalloprotease
BS614_RS23020	COG0497	DNA recombination
BS614_RS23025	COG1438	arginine binding
BS614_RS23035	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BS614_RS23040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BS614_RS23050	COG1722	exodeoxyribonuclease VII activity
BS614_RS23055	COG1570	exodeoxyribonuclease VII activity
BS614_RS23060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BS614_RS23065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BS614_RS23080	COG1302	Protein conserved in bacteria
BS614_RS23085	COG0439	Biotin carboxylase
BS614_RS23090	COG0511	ligase activity, forming carbon-carbon bonds
BS614_RS23130	COG3854	ATPases associated with a variety of cellular activities
BS614_RS23135	COG2045	Belongs to the ComB family
BS614_RS23145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BS614_RS23150	COG0006	proline dipeptidase activity
BS614_RS23155	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BS614_RS23165	COG3872	metal-dependent enzyme
BS614_RS23175	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS614_RS23180	COG1649	PFAM Uncharacterised BCR, COG1649
BS614_RS23185	COG1321	iron dependent repressor
BS614_RS23190	COG1533	DNA photolyase activity
BS614_RS23195	COG0785	Cytochrome C biogenesis protein
BS614_RS23200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS614_RS23205	COG1121	(ABC) transporter
BS614_RS23215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS614_RS23215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS614_RS23220	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BS614_RS23225	COG0735	belongs to the Fur family
BS614_RS23235	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS23240	COG4753	response regulator
BS614_RS23240	COG2207	Transcriptional regulator
BS614_RS23245	COG2972	Histidine kinase
BS614_RS23250	COG0395	ABC-type sugar transport system, permease component
BS614_RS23255	COG1175	transmembrane transport
BS614_RS23265	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BS614_RS23270	COG1882	Formate acetyltransferase
BS614_RS23275	COG1454	alcohol dehydrogenase
BS614_RS23275	COG1012	belongs to the aldehyde dehydrogenase family
BS614_RS23280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS614_RS23295	COG1733	regulation of RNA biosynthetic process
BS614_RS23325	COG0673	inositol 2-dehydrogenase activity
BS614_RS23335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS614_RS23335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS614_RS23345	COG4876	unkown
BS614_RS23350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS614_RS23375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS614_RS23380	COG3547	Transposase (IS116 IS110 IS902 family)
BS614_RS23385	COG1199	ATP-dependent helicase activity
BS614_RS23390	COG0753	catalase activity
BS614_RS23475	COG3022	response to hydroperoxide
BS614_RS23510	COG0477	Major facilitator Superfamily
BS614_RS23515	COG0395	ABC-type sugar transport system, permease component
BS614_RS23520	COG1175	transmembrane transport
BS614_RS23525	COG1653	transport
BS614_RS23530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS614_RS23535	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS23535	COG2207	Transcriptional regulator
BS614_RS23550	COG0745	RESPONSE REGULATOR receiver
BS614_RS23570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS614_RS23580	COG2066	Belongs to the glutaminase family
BS614_RS23590	COG2223	nitrite transmembrane transporter activity
BS614_RS23595	COG3279	Response regulator of the LytR AlgR family
BS614_RS23600	COG3275	phosphorelay sensor kinase activity
BS614_RS23615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BS614_RS23620	COG1307	EDD domain protein, DegV family
BS614_RS23625	COG1461	Dihydroxyacetone kinase
BS614_RS23630	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BS614_RS23645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BS614_RS23650	COG1162	GTPase activity
BS614_RS23655	COG2815	serine threonine protein kinase
BS614_RS23655	COG0515	serine threonine protein kinase
BS614_RS23660	COG0631	protein serine/threonine phosphatase activity
BS614_RS23665	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BS614_RS23670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BS614_RS23670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BS614_RS23675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BS614_RS23680	COG0242	peptide deformylase activity
BS614_RS23685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS614_RS23690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS614_RS23695	COG1758	RNA polymerase activity
BS614_RS23700	COG0194	GDP metabolic process
BS614_RS23705	COG2052	Domain of unknown function (DUF370)
BS614_RS23710	COG1561	YicC-like family, N-terminal region
BS614_RS23715	COG0646	methionine synthase
BS614_RS23715	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BS614_RS23720	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BS614_RS23725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BS614_RS23730	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BS614_RS23740	COG0613	PHP domain protein
BS614_RS23745	COG0583	DNA-binding transcription factor activity
BS614_RS23755	COG4471	UPF0298 protein
BS614_RS23775	COG1473	amidohydrolase
BS614_RS23785	COG0772	Belongs to the SEDS family
BS614_RS23790	COG1302	Protein conserved in bacteria
BS614_RS23795	COG0387	Pfam Sodium calcium exchanger
BS614_RS23800	COG4838	Belongs to the UPF0358 family
BS614_RS23810	COG2309	aminopeptidase activity
BS614_RS23820	COG2203	Gaf domain
BS614_RS23820	COG2199	diguanylate cyclase activity
BS614_RS23825	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BS614_RS23830	COG0840	transmembrane signaling receptor activity
BS614_RS23840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS614_RS23845	COG0454	-acetyltransferase
BS614_RS23850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BS614_RS23855	COG1609	Transcriptional regulator
BS614_RS23870	COG0693	protein deglycase activity
BS614_RS23875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BS614_RS23880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS23880	COG1263	PTS System
BS614_RS23880	COG2190	(PTS) system
BS614_RS23885	COG1832	CoA-binding protein
BS614_RS23890	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BS614_RS23895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS614_RS23900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BS614_RS23905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BS614_RS23915	COG0477	Major facilitator Superfamily
BS614_RS23920	COG1982	Orn Lys Arg decarboxylase major
BS614_RS23925	COG3906	Belongs to the UPF0473 family
BS614_RS23945	COG1764	response to oxidative stress
BS614_RS23985	COG2135	peptidase activity
BS614_RS24055	COG2153	protein acetylation
BS614_RS24085	COG3546	catalase activity
BS614_RS24130	COG1132	(ABC) transporter
BS614_RS24135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS614_RS24140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS614_RS24145	COG0584	glycerophosphoryl diester phosphodiesterase
BS614_RS24155	COG1611	Belongs to the LOG family
BS614_RS24165	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BS614_RS24170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BS614_RS24200	COG3209	COG3209 Rhs family protein
BS614_RS24205	COG0784	Response regulator, receiver
BS614_RS24205	COG5002	protein histidine kinase activity
BS614_RS24205	COG2205	protein histidine kinase activity
BS614_RS24215	COG2211	Major facilitator Superfamily
BS614_RS24235	COG0596	Alpha beta hydrolase
BS614_RS24265	COG1136	(ABC) transporter
BS614_RS24275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS614_RS24280	COG1136	(ABC) transporter
BS614_RS24290	COG0284	orotidine-5'-phosphate decarboxylase activity
BS614_RS24305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BS614_RS24310	COG0540	Belongs to the ATCase OTCase family
BS614_RS24315	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BS614_RS24350	COG0436	Aminotransferase
BS614_RS24355	COG0564	pseudouridine synthase activity
BS614_RS24360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BS614_RS24365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS614_RS24385	COG3599	regulation of cell shape
BS614_RS24390	COG2302	S4 RNA-binding domain
BS614_RS24395	COG0762	integral membrane protein
BS614_RS24400	COG1799	cell septum assembly
BS614_RS24405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BS614_RS24410	COG1496	oxidoreductase activity
BS614_RS24415	COG1873	PFAM PRC-barrel domain
BS614_RS24420	COG1191	sigma factor activity
BS614_RS24425	COG1191	sigma factor activity
BS614_RS24435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BS614_RS24440	COG0849	cell division
BS614_RS24445	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BS614_RS24450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BS614_RS24465	COG0772	Belongs to the SEDS family
BS614_RS24470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BS614_RS24475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS614_RS24480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BS614_RS24490	COG0768	penicillin binding
BS614_RS24495	COG0768	penicillin binding
BS614_RS24505	COG0275	rRNA processing
BS614_RS24510	COG2001	Belongs to the MraZ family
BS614_RS24515	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BS614_RS24520	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BS614_RS24525	COG4172	Belongs to the ABC transporter superfamily
BS614_RS24530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS614_RS24535	COG0601	transmembrane transport
BS614_RS24540	COG4166	transmembrane transport
BS614_RS24550	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS614_RS24575	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BS614_RS24590	COG1316	TRANSCRIPTIONal
BS614_RS24600	COG1217	gtp-binding protein TYPA
BS614_RS24615	COG0861	Integral membrane protein TerC family
BS614_RS24620	COG0861	Integral membrane protein TerC family
BS614_RS24625	COG0301	tRNA thio-modification
BS614_RS24630	COG1104	cysteine desulfurase activity
BS614_RS24635	COG0741	lytic transglycosylase activity
BS614_RS24665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS614_RS24670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS614_RS24680	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BS614_RS24685	COG2384	SAM-dependent methyltransferase
BS614_RS24695	COG0358	DNA primase activity
BS614_RS24700	COG1671	Belongs to the UPF0178 family
BS614_RS24705	COG0751	glycine-tRNA ligase activity
BS614_RS24710	COG0752	glycyl-tRNA synthetase alpha subunit
BS614_RS24715	COG1381	Involved in DNA repair and RecF pathway recombination
BS614_RS24725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BS614_RS24735	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BS614_RS24740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BS614_RS24745	COG1480	7TM receptor with intracellular HD hydrolase
BS614_RS24750	COG1702	phosphate starvation-inducible protein PhoH
BS614_RS24770	COG4864	UPF0365 protein
BS614_RS24775	COG1030	water channel activity
BS614_RS24780	COG1610	YqeY-like protein
BS614_RS24785	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BS614_RS24790	COG0537	adenosine 5'-monophosphoramidase activity
BS614_RS24795	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS614_RS24800	COG0626	cystathionine gamma-synthase activity
BS614_RS24810	COG0419	ATPase involved in DNA repair
BS614_RS24815	COG0420	3'-5' exonuclease activity
BS614_RS24820	COG1074	ATP-dependent DNA helicase activity
BS614_RS24825	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BS614_RS24840	COG1283	sodium-dependent phosphate transmembrane transporter activity
BS614_RS24850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS614_RS24855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BS614_RS24860	COG1994	Peptidase M50
BS614_RS24865	COG2264	protein methyltransferase activity
BS614_RS24900	COG1420	regulation of RNA biosynthetic process
BS614_RS24910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS614_RS24915	COG0481	GTPase activity
BS614_RS24935	COG0268	Binds directly to 16S ribosomal RNA
BS614_RS24940	COG1466	dna polymerase III delta subunit
BS614_RS24950	COG1595	DNA-templated transcription, initiation
BS614_RS24960	COG0726	polysaccharide deacetylase
BS614_RS24980	COG1595	DNA-templated transcription, initiation
BS614_RS24990	COG0658	competence protein
BS614_RS24990	COG2333	competence protein COMEC
BS614_RS25000	COG1555	photosystem II stabilization
BS614_RS25005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS614_RS25010	COG0495	leucyl-tRNA aminoacylation
BS614_RS25020	COG2226	methyltransferase
BS614_RS25025	COG2996	Protein conserved in bacteria
BS614_RS25030	COG0799	negative regulation of ribosome biogenesis
BS614_RS25035	COG1713	HD superfamily hydrolase involved in NAD metabolism
BS614_RS25040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BS614_RS25045	COG1534	Rna-binding protein
BS614_RS25050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BS614_RS25055	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BS614_RS25060	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BS614_RS25065	COG1305	Transglutaminase-like
BS614_RS25075	COG0714	Associated with various cellular activities
BS614_RS25085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS614_RS25095	COG1363	Peptidase, m42
BS614_RS25125	COG3052	prosthetic group binding
BS614_RS25130	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BS614_RS25140	COG0583	DNA-binding transcription factor activity
BS614_RS25150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS614_RS25155	COG2146	nitrite reductase [NAD(P)H] activity
BS614_RS25160	COG2116	formate transmembrane transporter activity
BS614_RS25170	COG2207	Transcriptional regulator
BS614_RS25170	COG4753	response regulator
BS614_RS25175	COG2972	Histidine kinase
BS614_RS25180	COG1653	transport
BS614_RS25185	COG1175	transmembrane transport
BS614_RS25190	COG0395	ABC-type sugar transport system, permease component
BS614_RS25195	COG2814	Major facilitator Superfamily
BS614_RS25205	COG0577	efflux transmembrane transporter activity
BS614_RS25205	COG1136	(ABC) transporter
BS614_RS25215	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BS614_RS25235	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS614_RS25240	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS614_RS25245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BS614_RS25250	COG1960	acyl-CoA dehydrogenase activity
BS614_RS25275	COG1959	2 iron, 2 sulfur cluster binding
BS614_RS25280	COG0702	epimerase
BS614_RS25285	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BS614_RS25305	COG1404	Belongs to the peptidase S8 family
BS614_RS25315	COG0515	serine threonine protein kinase
BS614_RS25315	COG2815	serine threonine protein kinase
BS614_RS25320	COG0596	Alpha beta hydrolase
BS614_RS25325	COG3341	Caulimovirus viroplasmin
BS614_RS25325	COG0328	RNA-DNA hybrid ribonuclease activity
BS614_RS25330	COG2323	membrane
BS614_RS25335	COG1120	ATPase activity
BS614_RS25340	COG4139	cobalamin transport
BS614_RS25355	COG1522	sequence-specific DNA binding
BS614_RS25365	COG1113	amino acid transport
BS614_RS25405	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS25405	COG3693	PFAM glycoside hydrolase, family 10
BS614_RS25405	COG2382	esterase
BS614_RS25410	COG2814	Major facilitator Superfamily
BS614_RS25415	COG1397	ADP-ribosylglycohydrolase
BS614_RS25420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS614_RS25425	COG0246	Mannitol dehydrogenase
BS614_RS25465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS25485	COG1733	regulation of RNA biosynthetic process
BS614_RS25505	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS25510	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS25525	COG0840	transmembrane signaling receptor activity
BS614_RS25530	COG0436	Aminotransferase
BS614_RS25550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS25555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS614_RS25565	COG0492	ferredoxin-NADP+ reductase activity
BS614_RS25570	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BS614_RS25580	COG2190	(PTS) system
BS614_RS25580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS25580	COG1263	PTS System
BS614_RS25590	COG1151	hydroxylamine reductase activity
BS614_RS25595	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BS614_RS25610	COG2814	Major facilitator Superfamily
BS614_RS25620	COG3420	alginic acid biosynthetic process
BS614_RS25630	COG0596	Alpha beta hydrolase
BS614_RS25635	COG2814	Major facilitator Superfamily
BS614_RS25665	COG0071	Belongs to the small heat shock protein (HSP20) family
BS614_RS25675	COG2207	Transcriptional regulator
BS614_RS25675	COG0662	Cupin 2, conserved barrel domain protein
BS614_RS25690	COG2272	Belongs to the type-B carboxylesterase lipase family
BS614_RS25695	COG2207	Transcriptional regulator
BS614_RS25695	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS25700	COG1785	Belongs to the alkaline phosphatase family
BS614_RS25725	COG2207	Transcriptional regulator
BS614_RS25725	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS25730	COG1874	Beta-galactosidase
BS614_RS25740	COG1595	DNA-templated transcription, initiation
BS614_RS25770	COG2233	PERMEase
BS614_RS25775	COG0666	response to abiotic stimulus
BS614_RS25780	COG0583	DNA-binding transcription factor activity
BS614_RS25785	COG2190	(PTS) system
BS614_RS25785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS25785	COG1263	PTS System
BS614_RS25790	COG3711	transcriptional antiterminator
BS614_RS25800	COG2723	6-phospho-beta-galactosidase activity
BS614_RS25815	COG2197	response regulator
BS614_RS25835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS614_RS25850	COG1940	carbohydrate kinase activity
BS614_RS25870	COG0528	UMP kinase activity
BS614_RS25880	COG0693	protein deglycase activity
BS614_RS25885	COG3321	synthase
BS614_RS25885	COG0604	alcohol dehydrogenase
BS614_RS25890	COG0384	phenazine biosynthesis protein PhzF
BS614_RS25905	COG4305	rare lipoprotein A
BS614_RS25910	COG0475	glutathione-regulated potassium exporter activity
BS614_RS25915	COG0490	domain, Protein
BS614_RS25925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS614_RS25930	COG1357	PFAM Pentapeptide repeats (8 copies)
BS614_RS25940	COG0596	Alpha beta hydrolase
BS614_RS25945	COG0708	Exodeoxyribonuclease III
BS614_RS25965	COG3940	Belongs to the glycosyl hydrolase 43 family
BS614_RS25980	COG0395	ABC-type sugar transport system, permease component
BS614_RS25985	COG1175	transmembrane transport
BS614_RS25995	COG1609	Transcriptional regulator
BS614_RS26025	COG2508	Transcriptional regulator
BS614_RS26030	COG1116	anion transmembrane transporter activity
BS614_RS26035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS614_RS26045	COG0154	amidase activity
BS614_RS26050	COG0251	oxidation-reduction process
BS614_RS26055	COG0840	transmembrane signaling receptor activity
BS614_RS26065	COG1979	alcohol dehydrogenase
BS614_RS26085	COG2337	Toxic component of a toxin-antitoxin (TA) module
BS614_RS26095	COG0586	Pfam SNARE associated Golgi protein
BS614_RS26135	COG1309	transcriptional regulator
BS614_RS26140	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS26165	COG1960	acyl-CoA dehydrogenase activity
BS614_RS26175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS614_RS26185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS614_RS26190	COG0367	asparagine synthase
BS614_RS26205	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BS614_RS26215	COG1509	lysine 2,3-aminomutase activity
BS614_RS26230	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS614_RS26260	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BS614_RS26270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BS614_RS26285	COG2378	regulation of single-species biofilm formation
BS614_RS26290	COG1361	Conserved repeat domain
BS614_RS26315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS614_RS26320	COG0581	inorganic phosphate transmembrane transporter activity
BS614_RS26325	COG0573	inorganic phosphate transmembrane transporter activity
BS614_RS26340	COG1082	Xylose isomerase domain protein TIM barrel
BS614_RS26345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS614_RS26350	COG2814	Major facilitator Superfamily
BS614_RS26360	COG2814	Major facilitator Superfamily
BS614_RS26370	COG1940	carbohydrate kinase activity
BS614_RS26375	COG1621	beta-fructofuranosidase activity
BS614_RS26385	COG0395	ABC-type sugar transport system, permease component
BS614_RS26390	COG4209	transmembrane transport
BS614_RS26395	COG1609	Transcriptional regulator
BS614_RS26420	COG2318	DinB family
BS614_RS26440	COG1335	isochorismatase
BS614_RS26450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BS614_RS26450	COG0456	acetyltransferase
BS614_RS26460	COG3507	Belongs to the glycosyl hydrolase 43 family
BS614_RS26510	COG0402	S-adenosylhomocysteine deaminase activity
BS614_RS26515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS614_RS26525	COG2239	Acts as a magnesium transporter
BS614_RS26530	COG4214	carbohydrate transport
BS614_RS26540	COG4213	ABC transporter substrate-binding protein
BS614_RS26545	COG4753	response regulator
BS614_RS26545	COG2207	Transcriptional regulator
BS614_RS26550	COG2972	Histidine kinase
BS614_RS26575	COG0671	phosphoesterase, PA-phosphatase related
BS614_RS26580	COG2723	6-phospho-beta-galactosidase activity
BS614_RS26585	COG2378	regulation of single-species biofilm formation
BS614_RS26610	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BS614_RS26615	COG3214	Protein conserved in bacteria
BS614_RS26635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS614_RS26645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS614_RS26655	COG0861	Integral membrane protein TerC family
BS614_RS26660	COG2814	Major facilitator Superfamily
BS614_RS26685	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BS614_RS26690	COG1523	belongs to the glycosyl hydrolase 13 family
BS614_RS26695	COG1523	belongs to the glycosyl hydrolase 13 family
BS614_RS26705	COG2911	Protein conserved in bacteria
BS614_RS26705	COG3266	domain, Protein
BS614_RS26705	COG1361	Conserved repeat domain
BS614_RS26710	COG1653	transport
BS614_RS26715	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS614_RS26720	COG1653	transport
BS614_RS26725	COG0395	ABC-type sugar transport system, permease component
BS614_RS26730	COG4209	transmembrane transport
BS614_RS26735	COG2207	Transcriptional regulator
BS614_RS26740	COG1193	negative regulation of DNA recombination
BS614_RS26750	COG0246	Mannitol dehydrogenase
BS614_RS26755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS614_RS26760	COG3711	transcriptional antiterminator
BS614_RS26770	COG0509	glycine decarboxylation via glycine cleavage system
BS614_RS26775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BS614_RS26780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BS614_RS26785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BS614_RS26790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BS614_RS26800	COG2190	(PTS) system
BS614_RS26800	COG1263	PTS System
BS614_RS26800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS614_RS26805	COG3711	transcriptional antiterminator
BS614_RS26810	COG2268	Band 7 protein
BS614_RS26820	COG1979	alcohol dehydrogenase
BS614_RS26835	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BS614_RS26840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BS614_RS26845	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BS614_RS26855	COG0667	Aldo Keto reductase
BS614_RS26860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BS614_RS26865	COG0546	phosphoglycolate phosphatase activity
BS614_RS26875	COG0800	Aldolase
BS614_RS26880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS614_RS26885	COG3594	Acyltransferase
BS614_RS26895	COG0129	dihydroxy-acid dehydratase activity
BS614_RS26910	COG0768	penicillin binding
BS614_RS26915	COG0840	transmembrane signaling receptor activity
BS614_RS26920	COG0826	peptidase U32
BS614_RS26925	COG0826	peptidase U32
BS614_RS26930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BS614_RS26940	COG3906	Belongs to the UPF0473 family
BS614_RS26960	COG0628	permease
BS614_RS26975	COG1104	cysteine desulfurase activity
BS614_RS26985	COG1959	2 iron, 2 sulfur cluster binding
BS614_RS26990	COG0482	sulfurtransferase activity
BS614_RS26995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS614_RS27000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS614_RS27005	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BS614_RS27010	COG0583	DNA-binding transcription factor activity
BS614_RS27015	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS27025	COG3973	AAA domain
BS614_RS27035	COG1309	transcriptional regulator
BS614_RS27040	COG1132	(ABC) transporter
BS614_RS27050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BS614_RS27055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BS614_RS27060	COG0124	histidyl-tRNA synthetase
BS614_RS27065	COG0653	protein targeting
BS614_RS27075	COG0693	protein deglycase activity
BS614_RS27080	COG1490	D-aminoacyl-tRNA deacylase activity
BS614_RS27085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BS614_RS27095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS614_RS27100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BS614_RS27100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BS614_RS27105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS614_RS27110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS614_RS27110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS614_RS27115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS614_RS27115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS614_RS27125	COG2244	polysaccharide biosynthetic process
BS614_RS27130	COG2323	membrane
BS614_RS27140	COG1862	Preprotein translocase
BS614_RS27150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BS614_RS27155	COG2385	sporulation resulting in formation of a cellular spore
BS614_RS27155	COG2385	sporulation resulting in formation of a cellular spore
BS614_RS27160	COG2255	four-way junction helicase activity
BS614_RS27165	COG0632	four-way junction helicase activity
BS614_RS27170	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BS614_RS27250	COG0077	Prephenate dehydratase
BS614_RS27255	COG0083	homoserine kinase activity
BS614_RS27260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BS614_RS27265	COG0460	homoserine dehydrogenase
BS614_RS27270	COG4492	Belongs to the UPF0735 family
BS614_RS27275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BS614_RS27285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BS614_RS27290	COG2868	ribosomal protein
BS614_RS27295	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BS614_RS27300	COG1530	ribonuclease E activity
BS614_RS27305	COG1994	Peptidase M50
BS614_RS27310	COG0739	heme binding
BS614_RS27315	COG2894	cell division
BS614_RS27320	COG0850	regulation of cytokinetic process
BS614_RS27335	COG1077	Cell shape determining protein MreB Mrl
BS614_RS27340	COG2003	Belongs to the UPF0758 family
BS614_RS27345	COG0424	maF-like protein
BS614_RS27360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BS614_RS27365	COG0285	dihydrofolate synthase activity
BS614_RS27370	COG0525	valine-tRNA ligase activity
BS614_RS27375	COG1388	LysM domain
BS614_RS27385	COG0564	pseudouridine synthase activity
BS614_RS27390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS614_RS27395	COG0113	porphobilinogen synthase activity
BS614_RS27410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BS614_RS27410	COG1648	precorrin-2 dehydrogenase activity
BS614_RS27425	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BS614_RS27435	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BS614_RS27445	COG0470	DNA polymerase III
BS614_RS27445	COG1067	ATP-dependent peptidase activity
BS614_RS27450	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BS614_RS27455	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BS614_RS27460	COG0740	serine-type endopeptidase activity
BS614_RS27465	COG0544	peptidyl-prolyl cis-trans isomerase activity
BS614_RS27485	COG2801	Transposase and inactivated derivatives
BS614_RS27490	COG2807	transmembrane transport
BS614_RS27495	COG1404	Belongs to the peptidase S8 family
BS614_RS27500	COG4106	trans-aconitate 2-methyltransferase activity
BS614_RS27530	COG0367	asparagine synthase
BS614_RS27535	COG0840	transmembrane signaling receptor activity
BS614_RS27545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS614_RS27565	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BS614_RS27570	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BS614_RS27580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS614_RS27610	COG1801	Protein of unknown function DUF72
BS614_RS27615	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS614_RS27630	COG1653	transport
BS614_RS27635	COG0395	ABC-type sugar transport system, permease component
BS614_RS27640	COG4209	transmembrane transport
BS614_RS27645	COG2207	Transcriptional regulator
BS614_RS27650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS614_RS27660	COG4716	Myosin-crossreactive antigen
BS614_RS27665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BS614_RS27670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BS614_RS27675	COG3773	Cell wall hydrolase
BS614_RS27675	COG3409	Peptidoglycan-binding domain 1 protein
BS614_RS27690	COG4641	Protein conserved in bacteria
BS614_RS27690	COG1388	LysM domain
BS614_RS27700	COG4641	Protein conserved in bacteria
BS614_RS27700	COG1388	LysM domain
BS614_RS27705	COG0726	polysaccharide deacetylase
BS614_RS27710	COG1388	LysM domain
BS614_RS27710	COG4641	Protein conserved in bacteria
BS614_RS27720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BS614_RS27730	COG1737	Transcriptional regulator
BS614_RS27745	COG2197	response regulator
BS614_RS27770	COG1131	(ABC) transporter
BS614_RS27780	COG2814	Major facilitator Superfamily
BS614_RS27790	COG0438	transferase activity, transferring glycosyl groups
BS614_RS27800	COG1216	Glycosyl transferase, family 2
BS614_RS27805	COG0463	Glycosyl transferase, family 2
BS614_RS27805	COG1216	Glycosyl transferase, family 2
BS614_RS27820	COG1086	Polysaccharide biosynthesis protein
BS614_RS27835	COG4641	Protein conserved in bacteria
BS614_RS27865	COG1126	abc transporter atp-binding protein
BS614_RS27870	COG0765	amino acid transport
BS614_RS27875	COG0765	amino acid transport
BS614_RS27880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS614_RS27890	COG4149	molybdate abc transporter
BS614_RS27895	COG0725	ABC transporter, periplasmic molybdate-binding protein
BS614_RS27900	COG1910	domain protein
BS614_RS27910	COG1917	Cupin 2, conserved barrel domain protein
BS614_RS27910	COG4977	sequence-specific DNA binding
BS614_RS27920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BS614_RS27925	COG0523	cobalamin synthesis protein
BS614_RS27935	COG1473	amidohydrolase
BS614_RS27940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS614_RS27945	COG0583	DNA-binding transcription factor activity
BS614_RS27950	COG0431	NADPH-dependent FMN reductase
BS614_RS27955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS614_RS27970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS614_RS27975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BS614_RS27980	COG0463	Glycosyl transferase, family 2
BS614_RS27990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BS614_RS27995	COG0438	transferase activity, transferring glycosyl groups
BS614_RS27995	COG1216	Glycosyl transferase, family 2
BS614_RS28010	COG3227	Zinc metalloprotease (Elastase)
BS614_RS28030	COG0688	phosphatidylethanolamine metabolic process
BS614_RS28060	COG1131	(ABC) transporter
BS614_RS28070	COG0300	oxidoreductase activity
BS614_RS28080	COG0583	DNA-binding transcription factor activity
BS614_RS28085	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BS614_RS28100	COG1408	metallophosphoesterase
BS614_RS28105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BS614_RS28110	COG1053	succinate dehydrogenase
BS614_RS28115	COG2009	succinate dehydrogenase
BS614_RS28120	COG0583	DNA-binding transcription factor activity
BS614_RS28125	COG0569	domain protein
BS614_RS28130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS614_RS28140	COG0322	excinuclease ABC activity
BS614_RS28145	COG3118	belongs to the thioredoxin family
BS614_RS28150	COG1484	DNA-dependent DNA replication
BS614_RS28155	COG0383	alpha-mannosidase activity
BS614_RS28175	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS28180	COG0395	ABC-type sugar transport system, permease component
BS614_RS28185	COG4209	transmembrane transport
BS614_RS28190	COG1653	transport
BS614_RS28195	COG2207	Transcriptional regulator
BS614_RS28195	COG4753	response regulator
BS614_RS28200	COG2972	Histidine kinase
BS614_RS28210	COG0318	PFAM AMP-dependent synthetase and ligase
BS614_RS28215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS614_RS28225	COG1595	DNA-templated transcription, initiation
BS614_RS28235	COG0590	tRNA wobble adenosine to inosine editing
BS614_RS28265	COG3253	May function as heme-dependent peroxidase
BS614_RS28275	COG1252	NADH dehydrogenase
BS614_RS28300	COG0189	ligase activity
BS614_RS28310	COG0248	Ppx GppA phosphatase
BS614_RS28315	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BS614_RS28340	COG2962	Rard protein
BS614_RS28360	COG2910	NAD(P)H-binding
BS614_RS28400	COG0316	Belongs to the HesB IscA family
BS614_RS28405	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BS614_RS28410	COG1252	NADH dehydrogenase
BS614_RS28420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BS614_RS28425	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS28435	COG1464	Belongs to the NlpA lipoprotein family
BS614_RS28440	COG2011	ABC-type metal ion transport system permease component
BS614_RS28455	COG1612	heme a metabolic process
BS614_RS28460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS614_RS28480	COG0561	phosphatase activity
BS614_RS28485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS614_RS28490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS614_RS28490	COG1321	iron dependent repressor
BS614_RS28495	COG1121	(ABC) transporter
BS614_RS28500	COG0803	Belongs to the bacterial solute-binding protein 9 family
BS614_RS28505	COG0768	penicillin binding
BS614_RS28510	COG0768	penicillin binding
BS614_RS28530	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BS614_RS28540	COG1988	membrane-bound metal-dependent
BS614_RS28555	COG0180	Tryptophanyl-tRNA synthetase
BS614_RS28580	COG3093	addiction module antidote protein HigA
BS614_RS28595	COG2346	COG2346, Truncated hemoglobins
BS614_RS28600	COG3314	Sporulation integral membrane protein YlbJ
BS614_RS28605	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BS614_RS28610	COG4470	Protein conserved in bacteria
BS614_RS28620	COG0739	heme binding
BS614_RS28635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BS614_RS28640	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BS614_RS28645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BS614_RS28650	COG1733	regulation of RNA biosynthetic process
BS614_RS28675	COG1595	DNA-templated transcription, initiation
BS614_RS28685	COG5002	protein histidine kinase activity
BS614_RS28690	COG0586	Pfam SNARE associated Golgi protein
BS614_RS28695	COG3963	phosphatidate phosphatase activity
BS614_RS28710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BS614_RS28715	COG0300	oxidoreductase activity
BS614_RS28720	COG1309	transcriptional regulator
BS614_RS28730	COG1902	pentaerythritol trinitrate reductase activity
BS614_RS28750	COG2723	6-phospho-beta-galactosidase activity
BS614_RS28755	COG3250	beta-galactosidase activity
BS614_RS28765	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS28770	COG1472	Belongs to the glycosyl hydrolase 3 family
BS614_RS28785	COG0395	ABC-type sugar transport system, permease component
BS614_RS28800	COG2207	Transcriptional regulator
BS614_RS28805	COG3275	phosphorelay sensor kinase activity
BS614_RS28820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS614_RS28825	COG0569	domain protein
BS614_RS28835	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BS614_RS28840	COG2259	Doxx family
BS614_RS28845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BS614_RS28855	COG2197	response regulator
BS614_RS28860	COG4585	Histidine kinase
BS614_RS28870	COG1842	Phage shock protein A
BS614_RS28880	COG1983	PspC domain protein
BS614_RS28895	COG2207	Transcriptional regulator
BS614_RS29000	COG3858	chitin binding
BS614_RS29005	COG0735	belongs to the Fur family
BS614_RS29020	COG1285	pathogenesis
BS614_RS29025	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BS614_RS29025	COG0456	acetyltransferase
BS614_RS29030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS614_RS29035	COG0154	amidase activity
BS614_RS29040	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS614_RS29060	COG1595	DNA-templated transcription, initiation
BS614_RS29070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS614_RS29080	COG0586	Pfam SNARE associated Golgi protein
BS614_RS29115	COG4840	Belongs to the UPF0435 family
BS614_RS29120	COG1741	Belongs to the pirin family
BS614_RS29130	COG0671	phosphoesterase, PA-phosphatase related
BS614_RS29135	COG2261	transglycosylase associated protein
BS614_RS29155	COG1191	sigma factor activity
BS614_RS29165	COG1366	Belongs to the anti-sigma-factor antagonist family
BS614_RS29170	COG0784	Response regulator, receiver
BS614_RS29170	COG2205	protein histidine kinase activity
BS614_RS29175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BS614_RS29180	COG5002	protein histidine kinase activity
BS614_RS29180	COG2205	protein histidine kinase activity
BS614_RS29180	COG0784	Response regulator, receiver
BS614_RS29185	COG2208	phosphoserine phosphatase activity
BS614_RS29215	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS614_RS29225	COG0488	(ABC) transporter
BS614_RS29240	COG1294	oxidase, subunit
BS614_RS29245	COG1271	oxidase subunit
BS614_RS29255	COG0745	RESPONSE REGULATOR receiver
BS614_RS29265	COG1413	lyase activity
BS614_RS29270	COG0833	amino acid
BS614_RS29300	COG0800	Aldolase
BS614_RS29305	COG2814	Major facilitator Superfamily
BS614_RS29310	COG1959	2 iron, 2 sulfur cluster binding
BS614_RS29315	COG0463	Glycosyl transferase, family 2
BS614_RS29315	COG0457	Tetratricopeptide repeat
BS614_RS29325	COG1070	Carbohydrate kinase
BS614_RS29330	COG2115	Belongs to the xylose isomerase family
BS614_RS29360	COG2267	carboxylic ester hydrolase activity
BS614_RS29365	COG2217	Heavy metal translocating P-type atpase
BS614_RS29380	COG1028	Short-chain dehydrogenase reductase Sdr
BS614_RS29385	COG1349	DNA-binding transcription factor activity
BS614_RS29390	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BS614_RS29410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BS614_RS29415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS614_RS29425	COG2723	6-phospho-beta-galactosidase activity
BS614_RS29445	COG1653	transport
BS614_RS29450	COG0395	ABC-type sugar transport system, permease component
BS614_RS29455	COG4209	transmembrane transport
BS614_RS29465	COG2197	response regulator
BS614_RS29485	COG1126	abc transporter atp-binding protein
BS614_RS29490	COG0765	amino acid transport
BS614_RS29495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS614_RS29500	COG1309	transcriptional regulator
BS614_RS29505	COG1968	undecaprenyl-diphosphatase activity
BS614_RS29515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS614_RS29520	COG0667	Aldo Keto reductase
BS614_RS29530	COG2322	membrane
BS614_RS29535	COG0475	glutathione-regulated potassium exporter activity
BS614_RS29545	COG0586	Pfam SNARE associated Golgi protein
BS614_RS29550	COG1183	phosphatidylcholine synthase activity
BS614_RS29555	COG5002	protein histidine kinase activity
BS614_RS29560	COG0745	RESPONSE REGULATOR receiver
BS614_RS29565	COG0351	phosphomethylpyrimidine kinase
BS614_RS29575	COG1131	(ABC) transporter
BS614_RS29580	COG2205	protein histidine kinase activity
BS614_RS29585	COG0745	RESPONSE REGULATOR receiver
BS614_RS29605	COG1131	(ABC) transporter
BS614_RS29650	COG1609	Transcriptional regulator
BS614_RS29700	COG1653	transport
BS614_RS29705	COG4753	response regulator
BS614_RS29705	COG2207	Transcriptional regulator
BS614_RS29710	COG3275	phosphorelay sensor kinase activity
BS614_RS29720	COG4209	transmembrane transport
BS614_RS29725	COG0395	ABC-type sugar transport system, permease component
BS614_RS29765	COG0640	Transcriptional regulator
BS614_RS29770	COG2814	Major facilitator Superfamily
BS614_RS29795	COG0667	Aldo Keto reductase
BS614_RS29815	COG1126	abc transporter atp-binding protein
BS614_RS29820	COG0765	amino acid transport
BS614_RS29825	COG2843	Capsule synthesis protein
BS614_RS29830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS614_RS29835	COG0745	RESPONSE REGULATOR receiver
BS614_RS29840	COG5002	protein histidine kinase activity
BS614_RS29855	COG2040	homocysteine
BS614_RS29860	COG0833	amino acid
BS614_RS29870	COG0531	amino acid
BS614_RS29875	COG0697	spore germination
BS614_RS29900	COG2807	transmembrane transport
BS614_RS29905	COG0583	DNA-binding transcription factor activity
BS614_RS29920	COG1132	(ABC) transporter
BS614_RS29955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS614_RS29965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BS614_RS29970	COG5662	AntiSigma factor
BS614_RS29975	COG1595	DNA-templated transcription, initiation
BS614_RS29980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BS614_RS30090	COG0726	polysaccharide deacetylase
BS614_RS30105	COG0489	protein tyrosine kinase activity
BS614_RS30110	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS614_RS30115	COG2046	Belongs to the sulfate adenylyltransferase family
BS614_RS30120	COG0175	sulfate reduction
BS614_RS30125	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BS614_RS30130	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BS614_RS30135	COG0101	tRNA pseudouridine synthase activity
BS614_RS30140	COG0203	ribosomal protein L17
BS614_RS30145	COG0202	RNA polymerase activity
BS614_RS30150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BS614_RS30155	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BS614_RS30160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BS614_RS30165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BS614_RS30170	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BS614_RS30175	COG0024	Methionine aminopeptidase
BS614_RS30180	COG0563	adenylate kinase activity
BS614_RS30185	COG0201	protein transport
BS614_RS30190	COG0200	Binds to the 23S rRNA
BS614_RS30195	COG1841	ribosomal large subunit assembly
BS614_RS30200	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BS614_RS30205	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BS614_RS30210	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BS614_RS30220	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BS614_RS30225	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BS614_RS30230	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BS614_RS30235	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BS614_RS30240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BS614_RS30245	COG0255	Belongs to the universal ribosomal protein uL29 family
BS614_RS30250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BS614_RS30255	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BS614_RS30260	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BS614_RS30265	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BS614_RS30270	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BS614_RS30275	COG0089	rRNA binding
BS614_RS30280	COG0088	Forms part of the polypeptide exit tunnel
BS614_RS30285	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BS614_RS30295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BS614_RS30300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BS614_RS30305	COG0049	tRNA binding
BS614_RS30310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BS614_RS30315	COG1358	cellular component organization or biogenesis
BS614_RS30320	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BS614_RS30325	COG0085	RNA polymerase activity
BS614_RS30330	COG2813	Specifically methylates the guanine in position
BS614_RS30335	COG0222	ribosome binding
BS614_RS30340	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BS614_RS30345	COG0081	regulation of translation
BS614_RS30350	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BS614_RS30355	COG0250	Participates in transcription elongation, termination and antitermination
BS614_RS30360	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS614_RS30365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BS614_RS30375	COG3688	RNA-binding protein containing a PIN domain
BS614_RS30380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS614_RS30385	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BS614_RS30390	COG0215	cysteine-tRNA ligase activity
BS614_RS30395	COG1045	serine acetyltransferase
BS614_RS30400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BS614_RS30405	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BS614_RS30410	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BS614_RS30415	COG4956	integral membrane protein (PIN domain superfamily)
BS614_RS30425	COG1183	phosphatidylcholine synthase activity
BS614_RS30430	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BS614_RS30435	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BS614_RS30440	COG0542	response to heat
BS614_RS30445	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BS614_RS30450	COG3880	PFAM UvrB UvrC protein
BS614_RS30490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BS614_RS30495	COG0210	DNA helicase
BS614_RS30500	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BS614_RS30510	COG1091	dTDP-4-dehydrorhamnose reductase activity
BS614_RS30525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS614_RS30530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS614_RS30535	COG0826	peptidase U32
BS614_RS30545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS614_RS30555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BS614_RS30560	COG0556	nucleotide-excision repair
BS614_RS30565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BS614_RS30570	COG1360	Flagellar Motor Protein
BS614_RS30575	COG0842	Transport permease protein
BS614_RS30585	COG1131	(ABC) transporter
BS614_RS30595	COG4585	Histidine kinase
BS614_RS30600	COG2197	response regulator
BS614_RS30605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS614_RS30610	COG0793	Belongs to the peptidase S41A family
BS614_RS30610	COG3409	Peptidoglycan-binding domain 1 protein
BS614_RS30615	COG0739	heme binding
BS614_RS30620	COG2177	Part of the ABC transporter FtsEX involved in
BS614_RS30625	COG2884	Cell division ATP-binding protein ftsE
BS614_RS30630	COG2720	vancomycin resistance protein
BS614_RS30635	COG2814	Major facilitator Superfamily
BS614_RS30640	COG1664	Polymer-forming cytoskeletal
BS614_RS30650	COG0789	Transcriptional regulator
BS614_RS30660	COG0165	Argininosuccinate lyase
BS614_RS30665	COG0137	argininosuccinate synthase activity
BS614_RS30675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BS614_RS30685	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BS614_RS30690	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BS614_RS30695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BS614_RS30700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS614_RS30705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS614_RS30710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BS614_RS30715	COG0653	protein targeting
BS614_RS30720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BS614_RS30725	COG1278	Cold shock
BS614_RS30750	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BS614_RS30765	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BS614_RS30770	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum