locus-tag	class	description
BSF38_RS00015	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BSF38_RS00025	COG4804	nuclease activity
BSF38_RS00055	COG1196	nuclear chromosome segregation
BSF38_RS00170	COG1475	DNA binding
BSF38_RS00225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BSF38_RS00230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSF38_RS00235	COG0436	Aminotransferase
BSF38_RS00250	COG1012	belongs to the aldehyde dehydrogenase family
BSF38_RS00255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSF38_RS00260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BSF38_RS00285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSF38_RS00400	COG2062	phosphohistidine phosphatase, SixA
BSF38_RS00410	COG2304	oxidoreductase activity
BSF38_RS00435	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BSF38_RS00440	COG0445	tRNA wobble uridine modification
BSF38_RS00445	COG0745	RESPONSE REGULATOR receiver
BSF38_RS00455	COG2770	Histidine kinase
BSF38_RS00455	COG3437	response regulator, receiver
BSF38_RS00550	COG0439	Biotin carboxylase
BSF38_RS00555	COG0511	ligase activity, forming carbon-carbon bonds
BSF38_RS00560	COG0006	proline dipeptidase activity
BSF38_RS00585	COG1301	dicarboxylic acid transport
BSF38_RS00600	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BSF38_RS00625	COG3609	addiction module antidote protein, CC2985 family
BSF38_RS00660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSF38_RS00665	COG0784	Response regulator, receiver
BSF38_RS00665	COG2205	protein histidine kinase activity
BSF38_RS00670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSF38_RS00680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BSF38_RS00685	COG0573	inorganic phosphate transmembrane transporter activity
BSF38_RS00690	COG0581	inorganic phosphate transmembrane transporter activity
BSF38_RS00695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSF38_RS00705	COG1473	amidohydrolase
BSF38_RS00710	COG0745	RESPONSE REGULATOR receiver
BSF38_RS00715	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BSF38_RS00720	COG0492	ferredoxin-NADP+ reductase activity
BSF38_RS00730	COG5002	protein histidine kinase activity
BSF38_RS00735	COG3706	GGDEF domain
BSF38_RS00750	COG1131	(ABC) transporter
BSF38_RS00755	COG0187	DNA topoisomerase II activity
BSF38_RS00760	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSF38_RS00770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSF38_RS00820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSF38_RS00835	COG0189	ligase activity
BSF38_RS00840	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
BSF38_RS00855	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
BSF38_RS00860	COG1229	Formylmethanofuran dehydrogenase subunit A
BSF38_RS00875	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS00880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSF38_RS00895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSF38_RS00905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BSF38_RS00905	COG2124	cytochrome p450
BSF38_RS00910	COG1309	transcriptional regulator
BSF38_RS00945	COG1475	DNA binding
BSF38_RS00950	COG0463	Glycosyl transferase, family 2
BSF38_RS00970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSF38_RS01015	COG0673	inositol 2-dehydrogenase activity
BSF38_RS01035	COG1595	DNA-templated transcription, initiation
BSF38_RS01045	COG0534	Mate efflux family protein
BSF38_RS01060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BSF38_RS01070	COG2204	response regulator
BSF38_RS01080	COG0134	indole-3-glycerol-phosphate synthase activity
BSF38_RS01100	COG0484	heat shock protein binding
BSF38_RS01110	COG0840	transmembrane signaling receptor activity
BSF38_RS01135	COG2201	protein-glutamate methylesterase activity
BSF38_RS01140	COG2208	phosphoserine phosphatase activity
BSF38_RS01190	COG2271	Major facilitator Superfamily
BSF38_RS01210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSF38_RS01255	COG0531	amino acid
BSF38_RS01300	COG1704	LemA family
BSF38_RS01405	COG0673	inositol 2-dehydrogenase activity
BSF38_RS01410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BSF38_RS01420	COG1595	DNA-templated transcription, initiation
BSF38_RS01430	COG2814	Major facilitator Superfamily
BSF38_RS01450	COG2271	Major facilitator Superfamily
BSF38_RS01465	COG1132	(ABC) transporter
BSF38_RS01490	COG0657	acetylesterase activity
BSF38_RS01490	COG2755	lipolytic protein G-D-S-L family
BSF38_RS01505	COG3693	PFAM glycoside hydrolase, family 10
BSF38_RS01505	COG2382	esterase
BSF38_RS01535	COG0673	inositol 2-dehydrogenase activity
BSF38_RS01555	COG0543	2 iron, 2 sulfur cluster binding
BSF38_RS01560	COG1187	pseudouridine synthase activity
BSF38_RS01605	COG1959	2 iron, 2 sulfur cluster binding
BSF38_RS01620	COG1959	2 iron, 2 sulfur cluster binding
BSF38_RS01625	COG1678	Uncharacterized ACR, COG1678
BSF38_RS01630	COG0612	Peptidase, M16
BSF38_RS01665	COG3142	Participates in the control of copper homeostasis
BSF38_RS01680	COG0484	heat shock protein binding
BSF38_RS01735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSF38_RS01750	COG3250	beta-galactosidase activity
BSF38_RS01800	COG4821	SIS domain
BSF38_RS01815	COG4566	intracellular signal transduction
BSF38_RS01825	COG5002	protein histidine kinase activity
BSF38_RS01830	COG2204	response regulator
BSF38_RS01840	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BSF38_RS01850	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BSF38_RS01855	COG2205	protein histidine kinase activity
BSF38_RS01865	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS01880	COG1959	2 iron, 2 sulfur cluster binding
BSF38_RS01890	COG0242	peptide deformylase activity
BSF38_RS01895	COG3291	Pkd domain containing protein
BSF38_RS01910	COG0577	efflux transmembrane transporter activity
BSF38_RS01915	COG2226	methyltransferase
BSF38_RS01920	COG2226	methyltransferase
BSF38_RS01925	COG0300	oxidoreductase activity
BSF38_RS01930	COG2267	carboxylic ester hydrolase activity
BSF38_RS01945	COG0604	alcohol dehydrogenase
BSF38_RS01945	COG3321	synthase
BSF38_RS01955	COG0616	signal peptide processing
BSF38_RS01965	COG1678	Uncharacterized ACR, COG1678
BSF38_RS01970	COG1252	NADH dehydrogenase
BSF38_RS01985	COG0515	serine threonine protein kinase
BSF38_RS01985	COG2815	serine threonine protein kinase
BSF38_RS01990	COG0297	glycogen (starch) synthase activity
BSF38_RS02020	COG3852	Histidine kinase
BSF38_RS02050	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BSF38_RS02065	COG0251	oxidation-reduction process
BSF38_RS02075	COG2815	serine threonine protein kinase
BSF38_RS02075	COG0515	serine threonine protein kinase
BSF38_RS02110	COG0489	protein tyrosine kinase activity
BSF38_RS02135	COG0402	S-adenosylhomocysteine deaminase activity
BSF38_RS02140	COG3224	Antibiotic biosynthesis monooxygenase
BSF38_RS02160	COG0443	Heat shock 70 kDa protein
BSF38_RS02175	COG0443	Heat shock 70 kDa protein
BSF38_RS02190	COG0105	UTP biosynthetic process
BSF38_RS02200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSF38_RS02205	COG1573	uracil-dna glycosylase
BSF38_RS02240	COG2271	Major facilitator Superfamily
BSF38_RS02245	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSF38_RS02250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSF38_RS02250	COG0357	Ribosomal RNA small subunit methyltransferase G
BSF38_RS02255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSF38_RS02270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSF38_RS02300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSF38_RS02320	COG3940	Belongs to the glycosyl hydrolase 43 family
BSF38_RS02335	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS02435	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSF38_RS02455	COG2815	serine threonine protein kinase
BSF38_RS02455	COG0515	serine threonine protein kinase
BSF38_RS02465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSF38_RS02470	COG1196	nuclear chromosome segregation
BSF38_RS02490	COG1331	Highly conserved protein containing a thioredoxin domain
BSF38_RS02495	COG1361	Conserved repeat domain
BSF38_RS02505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSF38_RS02510	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BSF38_RS02510	COG0674	pyruvate-flavodoxin oxidoreductase activity
BSF38_RS02560	COG0640	Transcriptional regulator
BSF38_RS02575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSF38_RS02655	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BSF38_RS02670	COG0515	serine threonine protein kinase
BSF38_RS02670	COG2815	serine threonine protein kinase
BSF38_RS02710	COG1595	DNA-templated transcription, initiation
BSF38_RS02720	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSF38_RS02740	COG0302	gtp cyclohydrolase
BSF38_RS02745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSF38_RS02750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BSF38_RS02755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BSF38_RS02770	COG5650	phosphatidylinositol metabolic process
BSF38_RS02785	COG1032	radical SAM domain protein
BSF38_RS02800	COG2211	Major facilitator Superfamily
BSF38_RS02805	COG0667	Aldo Keto reductase
BSF38_RS02810	COG0095	Lipoate-protein ligase
BSF38_RS02895	COG0724	RNA recognition motif
BSF38_RS02980	COG0714	Associated with various cellular activities
BSF38_RS03015	COG4948	Mandelate Racemase Muconate Lactonizing
BSF38_RS03020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BSF38_RS03030	COG2271	Major facilitator Superfamily
BSF38_RS03090	COG0673	inositol 2-dehydrogenase activity
BSF38_RS03105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BSF38_RS03105	COG0646	methionine synthase
BSF38_RS03110	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BSF38_RS03130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSF38_RS03155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSF38_RS03160	COG0463	Glycosyl transferase, family 2
BSF38_RS03345	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BSF38_RS03350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSF38_RS03375	COG1132	(ABC) transporter
BSF38_RS03385	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSF38_RS03410	COG1132	(ABC) transporter
BSF38_RS03415	COG5002	protein histidine kinase activity
BSF38_RS03485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSF38_RS03495	COG0673	inositol 2-dehydrogenase activity
BSF38_RS03500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSF38_RS03505	COG0166	Belongs to the GPI family
BSF38_RS03535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSF38_RS03555	COG0673	inositol 2-dehydrogenase activity
BSF38_RS03575	COG0515	serine threonine protein kinase
BSF38_RS03575	COG0457	Tetratricopeptide repeat
BSF38_RS03605	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSF38_RS03700	COG0544	peptidyl-prolyl cis-trans isomerase activity
BSF38_RS03705	COG0740	serine-type endopeptidase activity
BSF38_RS03710	COG0740	serine-type endopeptidase activity
BSF38_RS03715	COG0494	nUDIX hydrolase
BSF38_RS03720	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSF38_RS03750	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BSF38_RS03755	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BSF38_RS03760	COG1984	allophanate hydrolase subunit 2
BSF38_RS03775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSF38_RS03780	COG0405	Gamma-glutamyltransferase
BSF38_RS03805	COG1215	transferase activity, transferring glycosyl groups
BSF38_RS03820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSF38_RS03830	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BSF38_RS03845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSF38_RS03850	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSF38_RS03875	COG0321	lipoyl(octanoyl) transferase activity
BSF38_RS03875	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BSF38_RS03880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSF38_RS03895	COG0653	protein targeting
BSF38_RS03900	COG1519	Transferase
BSF38_RS03945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSF38_RS03950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSF38_RS03955	COG0667	Aldo Keto reductase
BSF38_RS03980	COG1918	ferrous iron import across plasma membrane
BSF38_RS03980	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BSF38_RS04015	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BSF38_RS04020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSF38_RS04035	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSF38_RS04040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSF38_RS04045	COG0022	dehydrogenase e1 component
BSF38_RS04060	COG0724	RNA recognition motif
BSF38_RS04070	COG2897	thiosulfate sulfurtransferase activity
BSF38_RS04075	COG1063	alcohol dehydrogenase
BSF38_RS04105	COG3132	Protein of unknown function, DUF480
BSF38_RS04150	COG1490	D-aminoacyl-tRNA deacylase activity
BSF38_RS04155	COG1069	ribulokinase activity
BSF38_RS04160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSF38_RS04170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSF38_RS04170	COG4651	solute:proton antiporter activity
BSF38_RS04175	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSF38_RS04180	COG0154	amidase activity
BSF38_RS04185	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSF38_RS04205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSF38_RS04235	COG0367	asparagine synthase
BSF38_RS04240	COG3041	Addiction module toxin RelE StbE family
BSF38_RS04265	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSF38_RS04280	COG0501	Belongs to the peptidase M48B family
BSF38_RS04310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSF38_RS04315	COG0793	Belongs to the peptidase S41A family
BSF38_RS04340	COG0793	Belongs to the peptidase S41A family
BSF38_RS04360	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BSF38_RS04365	COG0714	Associated with various cellular activities
BSF38_RS04370	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS04380	COG1482	cell wall glycoprotein biosynthetic process
BSF38_RS04385	COG0805	protein transport
BSF38_RS04400	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BSF38_RS04405	COG0402	S-adenosylhomocysteine deaminase activity
BSF38_RS04410	COG1668	transmembrane transport
BSF38_RS04415	COG4555	ABC transporter
BSF38_RS04420	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BSF38_RS04445	COG1131	(ABC) transporter
BSF38_RS04465	COG0174	glutamine synthetase
BSF38_RS04470	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSF38_RS04480	COG1091	dTDP-4-dehydrorhamnose reductase activity
BSF38_RS04485	COG0693	protein deglycase activity
BSF38_RS04490	COG2115	Belongs to the xylose isomerase family
BSF38_RS04530	COG0717	Belongs to the dCTP deaminase family
BSF38_RS04565	COG0714	Associated with various cellular activities
BSF38_RS04590	COG2226	methyltransferase
BSF38_RS04655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSF38_RS04690	COG0714	Associated with various cellular activities
BSF38_RS04750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSF38_RS04760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSF38_RS04780	COG0742	ribosomal rna small subunit methyltransferase
BSF38_RS04815	COG0826	peptidase U32
BSF38_RS04865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSF38_RS04875	COG0525	valine-tRNA ligase activity
BSF38_RS04900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BSF38_RS04925	COG0831	urea catabolic process
BSF38_RS04955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSF38_RS04965	COG1968	undecaprenyl-diphosphatase activity
BSF38_RS05010	COG2815	serine threonine protein kinase
BSF38_RS05010	COG0515	serine threonine protein kinase
BSF38_RS05015	COG1914	H( )-stimulated, divalent metal cation uptake system
BSF38_RS05030	COG0784	Response regulator, receiver
BSF38_RS05030	COG2205	protein histidine kinase activity
BSF38_RS05035	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BSF38_RS05060	COG0515	serine threonine protein kinase
BSF38_RS05060	COG2815	serine threonine protein kinase
BSF38_RS05065	COG0825	malonyl-CoA metabolic process
BSF38_RS05075	COG2205	protein histidine kinase activity
BSF38_RS05080	COG0745	RESPONSE REGULATOR receiver
BSF38_RS05100	COG0673	inositol 2-dehydrogenase activity
BSF38_RS05105	COG1595	DNA-templated transcription, initiation
BSF38_RS05120	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSF38_RS05125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSF38_RS05135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSF38_RS05160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSF38_RS05165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BSF38_RS05170	COG0243	molybdopterin cofactor binding
BSF38_RS05175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSF38_RS05185	COG2084	Dehydrogenase
BSF38_RS05190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSF38_RS05200	COG0673	inositol 2-dehydrogenase activity
BSF38_RS05230	COG0673	inositol 2-dehydrogenase activity
BSF38_RS05245	COG1556	Lactate utilization protein
BSF38_RS05250	COG1139	Iron-sulfur cluster binding protein
BSF38_RS05255	COG0247	lactate metabolic process
BSF38_RS05260	COG1253	flavin adenine dinucleotide binding
BSF38_RS05290	COG0402	S-adenosylhomocysteine deaminase activity
BSF38_RS05310	COG0612	Peptidase, M16
BSF38_RS05330	COG0673	inositol 2-dehydrogenase activity
BSF38_RS05335	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSF38_RS05380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSF38_RS05380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSF38_RS05385	COG0237	dephospho-CoA kinase activity
BSF38_RS05390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BSF38_RS05395	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSF38_RS05405	COG0657	acetylesterase activity
BSF38_RS05415	COG2211	Major facilitator Superfamily
BSF38_RS05455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSF38_RS05460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSF38_RS05470	COG1666	GTP binding
BSF38_RS05515	COG0673	inositol 2-dehydrogenase activity
BSF38_RS05530	COG0071	Belongs to the small heat shock protein (HSP20) family
BSF38_RS05545	COG0515	serine threonine protein kinase
BSF38_RS05545	COG2815	serine threonine protein kinase
BSF38_RS05570	COG0477	Major facilitator Superfamily
BSF38_RS05575	COG0514	ATP-dependent DNA helicase (RecQ)
BSF38_RS05585	COG1597	lipid kinase activity
BSF38_RS05590	COG0488	(ABC) transporter
BSF38_RS05615	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BSF38_RS05620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSF38_RS05620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSF38_RS05645	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSF38_RS05660	COG0776	regulation of translation
BSF38_RS05670	COG0727	PFAM Uncharacterised protein family (UPF0153)
BSF38_RS05685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSF38_RS05690	COG0314	molybdopterin synthase activity
BSF38_RS05705	COG3173	Aminoglycoside phosphotransferase
BSF38_RS05725	COG0577	efflux transmembrane transporter activity
BSF38_RS05725	COG1136	(ABC) transporter
BSF38_RS05795	COG0667	Aldo Keto reductase
BSF38_RS05820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSF38_RS05825	COG4591	ABC-type transport system involved in lipoprotein release permease component
BSF38_RS05830	COG1136	(ABC) transporter
BSF38_RS05845	COG0494	nUDIX hydrolase
BSF38_RS05850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSF38_RS05885	COG1595	DNA-templated transcription, initiation
BSF38_RS05890	COG0681	Belongs to the peptidase S26 family
BSF38_RS05985	COG0515	serine threonine protein kinase
BSF38_RS05990	COG1007	ATP synthesis coupled electron transport
BSF38_RS06000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSF38_RS06005	COG0713	ATP synthesis coupled electron transport
BSF38_RS06010	COG0839	Belongs to the complex I subunit 6 family
BSF38_RS06015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSF38_RS06020	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BSF38_RS06030	COG1034	ATP synthesis coupled electron transport
BSF38_RS06045	COG0649	NAD binding
BSF38_RS06050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSF38_RS06055	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSF38_RS06060	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSF38_RS06075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSF38_RS06080	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BSF38_RS06090	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSF38_RS06095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSF38_RS06120	COG4716	Myosin-crossreactive antigen
BSF38_RS06125	COG0842	Transport permease protein
BSF38_RS06130	COG1129	ABC transporter
BSF38_RS06130	COG0842	Transport permease protein
BSF38_RS06135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSF38_RS06175	COG1418	mRNA catabolic process
BSF38_RS06180	COG1692	metallophosphoesterase
BSF38_RS06190	COG0204	Acyl-transferase
BSF38_RS06190	COG0318	PFAM AMP-dependent synthetase and ligase
BSF38_RS06200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSF38_RS06215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSF38_RS06230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSF38_RS06240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSF38_RS06255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSF38_RS06290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSF38_RS06290	COG2813	Specifically methylates the guanine in position
BSF38_RS06335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSF38_RS06365	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
BSF38_RS06380	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BSF38_RS06410	COG3119	arylsulfatase activity
BSF38_RS06490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSF38_RS06495	COG4279	zinc finger
BSF38_RS06500	COG3250	beta-galactosidase activity
BSF38_RS06530	COG4948	Mandelate Racemase Muconate Lactonizing
BSF38_RS06575	COG4413	Urea transporter
BSF38_RS06620	COG3622	Belongs to the hyi family
BSF38_RS06630	COG1879	ABC-type sugar transport system periplasmic component
BSF38_RS06635	COG1129	ABC transporter
BSF38_RS06640	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSF38_RS06645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSF38_RS06650	COG0126	phosphoglycerate kinase activity
BSF38_RS06660	COG2340	Cysteine-rich secretory protein family
BSF38_RS06665	COG2176	DNA-directed DNA polymerase activity
BSF38_RS06680	COG1012	belongs to the aldehyde dehydrogenase family
BSF38_RS06710	COG0673	inositol 2-dehydrogenase activity
BSF38_RS06725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BSF38_RS06765	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS06775	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS06780	COG1216	Glycosyl transferase, family 2
BSF38_RS06790	COG1215	transferase activity, transferring glycosyl groups
BSF38_RS06800	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS06815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSF38_RS06830	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSF38_RS06845	COG3206	protein involved in exopolysaccharide biosynthesis
BSF38_RS06845	COG0489	protein tyrosine kinase activity
BSF38_RS06850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSF38_RS06895	COG4191	Histidine kinase
BSF38_RS06900	COG2204	response regulator
BSF38_RS06910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSF38_RS06945	COG0501	Belongs to the peptidase M48B family
BSF38_RS06960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSF38_RS06965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSF38_RS06975	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BSF38_RS07005	COG2208	phosphoserine phosphatase activity
BSF38_RS07010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSF38_RS07020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSF38_RS07040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSF38_RS07045	COG0778	Nitroreductase
BSF38_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS07055	COG0673	inositol 2-dehydrogenase activity
BSF38_RS07060	COG1840	ABC-type Fe3 transport system, periplasmic component
BSF38_RS07065	COG1595	DNA-templated transcription, initiation
BSF38_RS07075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSF38_RS07105	COG2890	protein-(glutamine-N5) methyltransferase activity
BSF38_RS07125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSF38_RS07140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSF38_RS07150	COG0745	RESPONSE REGULATOR receiver
BSF38_RS07155	COG4191	Histidine kinase
BSF38_RS07160	COG2208	phosphoserine phosphatase activity
BSF38_RS07165	COG2267	carboxylic ester hydrolase activity
BSF38_RS07170	COG0758	DNA mediated transformation
BSF38_RS07170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSF38_RS07175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSF38_RS07200	COG1104	cysteine desulfurase activity
BSF38_RS07205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BSF38_RS07210	COG0484	heat shock protein binding
BSF38_RS07215	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BSF38_RS07265	COG1215	transferase activity, transferring glycosyl groups
BSF38_RS07280	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BSF38_RS07290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSF38_RS07315	COG0138	bifunctional purine biosynthesis protein purh
BSF38_RS07335	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BSF38_RS07340	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BSF38_RS07360	COG0577	efflux transmembrane transporter activity
BSF38_RS07360	COG1136	(ABC) transporter
BSF38_RS07385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSF38_RS07390	COG0723	plastoquinol--plastocyanin reductase activity
BSF38_RS07395	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BSF38_RS07400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSF38_RS07430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS07445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS07455	COG3842	ATPase activity
BSF38_RS07460	COG1063	alcohol dehydrogenase
BSF38_RS07470	COG0505	Belongs to the CarA family
BSF38_RS07490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BSF38_RS07495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSF38_RS07500	COG4589	Belongs to the CDS family
BSF38_RS07505	COG1702	phosphate starvation-inducible protein PhoH
BSF38_RS07510	COG1480	7TM receptor with intracellular HD hydrolase
BSF38_RS07515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BSF38_RS07525	COG1381	Involved in DNA repair and RecF pathway recombination
BSF38_RS07540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BSF38_RS07545	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSF38_RS07555	COG2304	oxidoreductase activity
BSF38_RS07580	COG0531	amino acid
BSF38_RS07595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSF38_RS07600	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BSF38_RS07605	COG0724	RNA recognition motif
BSF38_RS07635	COG0356	it plays a direct role in the translocation of protons across the membrane
BSF38_RS07640	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSF38_RS07645	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSF38_RS07650	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSF38_RS07655	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSF38_RS07660	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSF38_RS07665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSF38_RS07670	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSF38_RS07675	COG1595	DNA-templated transcription, initiation
BSF38_RS07690	COG0217	transcriptional regulatory protein
BSF38_RS07720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSF38_RS07755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSF38_RS07765	COG0109	protoheme IX farnesyltransferase activity
BSF38_RS07770	COG1845	cytochrome c oxidase, subunit III
BSF38_RS07780	COG2322	membrane
BSF38_RS07795	COG0284	orotidine-5'-phosphate decarboxylase activity
BSF38_RS07820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSF38_RS07860	COG2208	phosphoserine phosphatase activity
BSF38_RS07880	COG0517	IMP dehydrogenase activity
BSF38_RS07880	COG1994	Peptidase M50
BSF38_RS07900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BSF38_RS07905	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSF38_RS07920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSF38_RS07935	COG3481	metal-dependent phosphohydrolase, HD sub domain
BSF38_RS07960	COG0004	ammonium transporteR
BSF38_RS07970	COG0584	glycerophosphoryl diester phosphodiesterase
BSF38_RS08005	COG0069	glutamate synthase activity
BSF38_RS08005	COG0067	glutamate synthase
BSF38_RS08005	COG0070	glutamate synthase
BSF38_RS08010	COG0583	DNA-binding transcription factor activity
BSF38_RS08015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSF38_RS08030	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BSF38_RS08045	COG0778	Nitroreductase
BSF38_RS08060	COG0531	amino acid
BSF38_RS08065	COG3265	gluconokinase activity
BSF38_RS08070	COG1966	Carbon starvation protein
BSF38_RS08110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BSF38_RS08125	COG1192	Involved in chromosome partitioning
BSF38_RS08135	COG0295	cytidine deaminase activity
BSF38_RS08140	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSF38_RS08180	COG3119	arylsulfatase activity
BSF38_RS08200	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSF38_RS08245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSF38_RS08285	COG0494	nUDIX hydrolase
BSF38_RS08290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSF38_RS08295	COG0470	DNA polymerase III
BSF38_RS08320	COG1136	(ABC) transporter
BSF38_RS08325	COG0577	efflux transmembrane transporter activity
BSF38_RS08325	COG1136	(ABC) transporter
BSF38_RS08330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSF38_RS08335	COG0564	pseudouridine synthase activity
BSF38_RS08365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSF38_RS08390	COG0824	Thioesterase
BSF38_RS08405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSF38_RS08420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSF38_RS08425	COG2814	Major facilitator Superfamily
BSF38_RS08450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSF38_RS08450	COG0574	Belongs to the PEP-utilizing enzyme family
BSF38_RS08460	COG2226	methyltransferase
BSF38_RS08465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSF38_RS08480	COG4956	integral membrane protein (PIN domain superfamily)
BSF38_RS08485	COG1595	DNA-templated transcription, initiation
BSF38_RS08490	COG0436	Aminotransferase
BSF38_RS08495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS08505	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSF38_RS08525	COG0542	response to heat
BSF38_RS08550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSF38_RS08555	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS08580	COG2226	methyltransferase
BSF38_RS08610	COG1216	Glycosyl transferase, family 2
BSF38_RS08620	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BSF38_RS08630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSF38_RS08630	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSF38_RS08640	COG1012	belongs to the aldehyde dehydrogenase family
BSF38_RS08650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSF38_RS08655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSF38_RS08670	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BSF38_RS08705	COG0318	PFAM AMP-dependent synthetase and ligase
BSF38_RS08710	COG1024	Enoyl-CoA hydratase
BSF38_RS08720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSF38_RS08730	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BSF38_RS08740	COG0673	inositol 2-dehydrogenase activity
BSF38_RS08765	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSF38_RS08775	COG0653	protein targeting
BSF38_RS08785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSF38_RS08800	COG1940	carbohydrate kinase activity
BSF38_RS08805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BSF38_RS08805	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BSF38_RS08810	COG0598	Magnesium transport protein CorA
BSF38_RS08845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSF38_RS08865	COG0673	inositol 2-dehydrogenase activity
BSF38_RS08885	COG1193	negative regulation of DNA recombination
BSF38_RS08905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSF38_RS08910	COG0509	glycine decarboxylation via glycine cleavage system
BSF38_RS08915	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSF38_RS08920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSF38_RS08925	COG1459	type II secretion system
BSF38_RS08950	COG0750	zinc metalloprotease
BSF38_RS08965	COG2815	serine threonine protein kinase
BSF38_RS08965	COG0515	serine threonine protein kinase
BSF38_RS08970	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BSF38_RS09010	COG0205	6-phosphofructokinase activity
BSF38_RS09030	COG0515	serine threonine protein kinase
BSF38_RS09030	COG2815	serine threonine protein kinase
BSF38_RS09035	COG1090	epimerase
BSF38_RS09045	COG3963	phosphatidate phosphatase activity
BSF38_RS09130	COG4864	UPF0365 protein
BSF38_RS09150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSF38_RS09165	COG0114	fumarate hydratase activity
BSF38_RS09175	COG1201	RNA secondary structure unwinding
BSF38_RS09190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSF38_RS09245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSF38_RS09250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSF38_RS09255	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BSF38_RS09255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSF38_RS09260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSF38_RS09265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSF38_RS09275	COG2234	aminopeptidase activity
BSF38_RS09285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSF38_RS09290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSF38_RS09305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSF38_RS09320	COG1733	regulation of RNA biosynthetic process
BSF38_RS09360	COG1595	DNA-templated transcription, initiation
BSF38_RS09370	COG0463	Glycosyl transferase, family 2
BSF38_RS09395	COG0242	peptide deformylase activity
BSF38_RS09400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSF38_RS09415	COG1032	radical SAM domain protein
BSF38_RS09420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSF38_RS09430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BSF38_RS09490	COG2124	cytochrome p450
BSF38_RS09500	COG0354	folic acid binding
BSF38_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS09545	COG0673	inositol 2-dehydrogenase activity
BSF38_RS09565	COG0713	ATP synthesis coupled electron transport
BSF38_RS09570	COG0839	Belongs to the complex I subunit 6 family
BSF38_RS09580	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSF38_RS09590	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSF38_RS09595	COG0649	NAD binding
BSF38_RS09605	COG0745	RESPONSE REGULATOR receiver
BSF38_RS09850	COG4191	Histidine kinase
BSF38_RS09855	COG0745	RESPONSE REGULATOR receiver
BSF38_RS09855	COG4566	intracellular signal transduction
BSF38_RS09860	COG3852	Histidine kinase
BSF38_RS09865	COG2201	protein-glutamate methylesterase activity
BSF38_RS09885	COG1960	acyl-CoA dehydrogenase activity
BSF38_RS09895	COG0183	Belongs to the thiolase family
BSF38_RS09905	COG0515	serine threonine protein kinase
BSF38_RS09905	COG2815	serine threonine protein kinase
BSF38_RS09915	COG1335	isochorismatase
BSF38_RS09950	COG0346	lactoylglutathione lyase activity
BSF38_RS09960	COG2080	2 iron, 2 sulfur cluster binding
BSF38_RS09965	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BSF38_RS09970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSF38_RS09995	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSF38_RS10005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSF38_RS10070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSF38_RS10070	COG0574	Belongs to the PEP-utilizing enzyme family
BSF38_RS10090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BSF38_RS10100	COG0071	Belongs to the small heat shock protein (HSP20) family
BSF38_RS10140	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BSF38_RS10175	COG0484	heat shock protein binding
BSF38_RS10200	COG0183	Belongs to the thiolase family
BSF38_RS10205	COG4770	biotin carboxylase activity
BSF38_RS10210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSF38_RS10215	COG1703	isobutyryl-CoA mutase activity
BSF38_RS10225	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSF38_RS10225	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSF38_RS10240	COG0824	Thioesterase
BSF38_RS10260	COG4770	biotin carboxylase activity
BSF38_RS10265	COG0346	lactoylglutathione lyase activity
BSF38_RS10275	COG1053	succinate dehydrogenase
BSF38_RS10280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BSF38_RS10300	COG0504	CTP synthase activity
BSF38_RS10305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BSF38_RS10310	COG0673	inositol 2-dehydrogenase activity
BSF38_RS10335	COG0463	Glycosyl transferase, family 2
BSF38_RS10355	COG1858	cytochrome C peroxidase
BSF38_RS10395	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSF38_RS10405	COG0823	Involved in the tonB-independent uptake of proteins
BSF38_RS10405	COG1506	peptidase
BSF38_RS10405	COG4946	Tricorn protease homolog
BSF38_RS10440	COG0475	glutathione-regulated potassium exporter activity
BSF38_RS10445	COG1217	gtp-binding protein TYPA
BSF38_RS10460	COG1525	nuclease
BSF38_RS10470	COG0673	inositol 2-dehydrogenase activity
BSF38_RS10495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSF38_RS10510	COG0617	tRNA 3'-terminal CCA addition
BSF38_RS10540	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BSF38_RS10555	COG0463	Glycosyl transferase, family 2
BSF38_RS10570	COG2308	Evidence 4 Homologs of previously reported genes of
BSF38_RS10600	COG0515	serine threonine protein kinase
BSF38_RS10600	COG2815	serine threonine protein kinase
BSF38_RS10610	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSF38_RS10620	COG0673	inositol 2-dehydrogenase activity
BSF38_RS10645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSF38_RS10665	COG3591	Belongs to the peptidase S1B family
BSF38_RS10665	COG4990	cell redox homeostasis
BSF38_RS10675	COG1285	pathogenesis
BSF38_RS10685	COG0288	reversible hydration of carbon dioxide
BSF38_RS10690	COG0831	urea catabolic process
BSF38_RS10695	COG0832	Belongs to the urease beta subunit family
BSF38_RS10705	COG0830	nickel cation binding
BSF38_RS10710	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BSF38_RS10715	COG0829	nickel cation binding
BSF38_RS10740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSF38_RS10745	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BSF38_RS10755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSF38_RS10795	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BSF38_RS10830	COG4948	Mandelate Racemase Muconate Lactonizing
BSF38_RS10875	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BSF38_RS10885	COG1796	DNA polymerase
BSF38_RS10885	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BSF38_RS10890	COG0488	(ABC) transporter
BSF38_RS10900	COG3540	Alkaline phosphatase
BSF38_RS10905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSF38_RS10935	COG2183	response to ionizing radiation
BSF38_RS10935	COG0539	negative regulation of cytoplasmic translation
BSF38_RS10965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSF38_RS10970	COG0667	Aldo Keto reductase
BSF38_RS10975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BSF38_RS10995	COG0586	Pfam SNARE associated Golgi protein
BSF38_RS11015	COG0310	cobalt ion transport
BSF38_RS11020	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BSF38_RS11025	COG1122	ATPase activity
BSF38_RS11120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSF38_RS11125	COG0488	(ABC) transporter
BSF38_RS11185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSF38_RS11190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS11195	COG3119	arylsulfatase activity
BSF38_RS11205	COG0746	molybdenum cofactor guanylyltransferase activity
BSF38_RS11210	COG0724	RNA recognition motif
BSF38_RS11235	COG0484	heat shock protein binding
BSF38_RS11245	COG1595	DNA-templated transcription, initiation
BSF38_RS11260	COG0259	pyridoxamine-phosphate oxidase activity
BSF38_RS11270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSF38_RS11280	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSF38_RS11285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BSF38_RS11295	COG0531	amino acid
BSF38_RS11300	COG0072	phenylalanine-tRNA ligase activity
BSF38_RS11320	COG1131	(ABC) transporter
BSF38_RS11325	COG1725	Transcriptional regulator
BSF38_RS11335	COG0673	inositol 2-dehydrogenase activity
BSF38_RS11355	COG1902	pentaerythritol trinitrate reductase activity
BSF38_RS11420	COG2815	serine threonine protein kinase
BSF38_RS11420	COG0515	serine threonine protein kinase
BSF38_RS11450	COG2255	four-way junction helicase activity
BSF38_RS11460	COG0459	protein refolding
BSF38_RS11465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSF38_RS11510	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS11530	COG0667	Aldo Keto reductase
BSF38_RS11565	COG2814	Major facilitator Superfamily
BSF38_RS11585	COG4149	molybdate abc transporter
BSF38_RS11590	COG0725	ABC transporter, periplasmic molybdate-binding protein
BSF38_RS11615	COG0515	serine threonine protein kinase
BSF38_RS11620	COG1595	DNA-templated transcription, initiation
BSF38_RS11630	COG1162	GTPase activity
BSF38_RS11650	COG0497	DNA recombination
BSF38_RS11655	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BSF38_RS11665	COG0827	DNA restriction-modification system
BSF38_RS11670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSF38_RS11670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSF38_RS11680	COG0305	Participates in initiation and elongation during chromosome replication
BSF38_RS11685	COG0359	binds to the 23S rRNA
BSF38_RS11690	COG0629	single-stranded DNA binding
BSF38_RS11700	COG0193	aminoacyl-tRNA hydrolase activity
BSF38_RS11705	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BSF38_RS11710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSF38_RS11725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSF38_RS11775	COG1214	PFAM Peptidase M22, glycoprotease
BSF38_RS11785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS11785	COG0706	membrane insertase activity
BSF38_RS11790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSF38_RS11795	COG4154	Belongs to the RbsD FucU family
BSF38_RS11810	COG2755	lipolytic protein G-D-S-L family
BSF38_RS11810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BSF38_RS11820	COG0124	histidyl-tRNA synthetase
BSF38_RS11825	COG0124	histidyl-tRNA synthetase
BSF38_RS11835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSF38_RS11845	COG0577	efflux transmembrane transporter activity
BSF38_RS11845	COG1136	(ABC) transporter
BSF38_RS11855	COG0657	acetylesterase activity
BSF38_RS11865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSF38_RS11895	COG2815	serine threonine protein kinase
BSF38_RS11895	COG0515	serine threonine protein kinase
BSF38_RS11935	COG4974	Belongs to the 'phage' integrase family
BSF38_RS11940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSF38_RS11950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BSF38_RS11965	COG0514	ATP-dependent DNA helicase (RecQ)
BSF38_RS11985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BSF38_RS11990	COG3119	arylsulfatase activity
BSF38_RS12010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS12010	COG5549	protein import
BSF38_RS12035	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSF38_RS12045	COG1201	RNA secondary structure unwinding
BSF38_RS12090	COG0531	amino acid
BSF38_RS12100	COG2226	methyltransferase
BSF38_RS12140	COG0028	Belongs to the TPP enzyme family
BSF38_RS12145	COG0427	acetyl-CoA hydrolase
BSF38_RS12155	COG4974	Belongs to the 'phage' integrase family
BSF38_RS12195	COG3852	Histidine kinase
BSF38_RS12205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSF38_RS12210	COG0457	Tetratricopeptide repeat
BSF38_RS12210	COG0705	Rhomboid family
BSF38_RS12230	COG0367	asparagine synthase
BSF38_RS12235	COG0412	Dienelactone hydrolase
BSF38_RS12240	COG2738	Putative neutral zinc metallopeptidase
BSF38_RS12245	COG2226	methyltransferase
BSF38_RS12250	COG0463	Glycosyl transferase, family 2
BSF38_RS12305	COG2801	Transposase and inactivated derivatives
BSF38_RS12320	COG1233	COG1233 Phytoene dehydrogenase and related
BSF38_RS12330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSF38_RS12340	COG0633	Ferredoxin
BSF38_RS12345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSF38_RS12360	COG1446	asparaginase
BSF38_RS12390	COG0058	SHG alpha-glucan phosphorylase activity
BSF38_RS12415	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BSF38_RS12420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BSF38_RS12435	COG1475	DNA binding
BSF38_RS12440	COG1192	Involved in chromosome partitioning
BSF38_RS12470	COG0693	protein deglycase activity
BSF38_RS12475	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BSF38_RS12500	COG0515	serine threonine protein kinase
BSF38_RS12500	COG2815	serine threonine protein kinase
BSF38_RS12525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSF38_RS12535	COG0442	prolyl-tRNA aminoacylation
BSF38_RS12545	COG3481	metal-dependent phosphohydrolase, HD sub domain
BSF38_RS12550	COG0557	exoribonuclease II activity
BSF38_RS12580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSF38_RS12585	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSF38_RS12595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSF38_RS12610	COG0612	Peptidase, M16
BSF38_RS12615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSF38_RS12625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSF38_RS12630	COG0463	Glycosyl transferase, family 2
BSF38_RS12685	COG0579	oxidoreductase
BSF38_RS12695	COG0561	phosphatase activity
BSF38_RS12720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS12730	COG0463	Glycosyl transferase, family 2
BSF38_RS12745	COG3781	membrane
BSF38_RS12760	COG0463	Glycosyl transferase, family 2
BSF38_RS12780	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSF38_RS12785	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BSF38_RS12805	COG0704	Plays a role in the regulation of phosphate uptake
BSF38_RS12820	COG0515	serine threonine protein kinase
BSF38_RS12820	COG2815	serine threonine protein kinase
BSF38_RS12855	COG0483	inositol monophosphate 1-phosphatase activity
BSF38_RS12890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSF38_RS12900	COG0590	tRNA wobble adenosine to inosine editing
BSF38_RS12905	COG1231	oxidoreductase activity
BSF38_RS12960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSF38_RS12970	COG1335	isochorismatase
BSF38_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS12980	COG0604	alcohol dehydrogenase
BSF38_RS12980	COG3321	synthase
BSF38_RS12985	COG1136	(ABC) transporter
BSF38_RS12990	COG0577	efflux transmembrane transporter activity
BSF38_RS12990	COG1136	(ABC) transporter
BSF38_RS12995	COG2183	response to ionizing radiation
BSF38_RS13035	COG0564	pseudouridine synthase activity
BSF38_RS13065	COG3177	Filamentation induced by cAMP protein fic
BSF38_RS13070	COG0705	Rhomboid family
BSF38_RS13070	COG0457	Tetratricopeptide repeat
BSF38_RS13080	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BSF38_RS13085	COG1595	DNA-templated transcription, initiation
BSF38_RS13100	COG0159	tryptophan synthase activity
BSF38_RS13105	COG0133	tryptophan synthase activity
BSF38_RS13115	COG1858	cytochrome C peroxidase
BSF38_RS13145	COG0673	inositol 2-dehydrogenase activity
BSF38_RS13150	COG0673	inositol 2-dehydrogenase activity
BSF38_RS13160	COG0673	inositol 2-dehydrogenase activity
BSF38_RS13165	COG0864	Transcriptional regulator
BSF38_RS13185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BSF38_RS13225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSF38_RS13230	COG0049	tRNA binding
BSF38_RS13235	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS13245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSF38_RS13250	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSF38_RS13260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSF38_RS13290	COG0142	geranyltranstransferase activity
BSF38_RS13300	COG1136	(ABC) transporter
BSF38_RS13300	COG0577	efflux transmembrane transporter activity
BSF38_RS13315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BSF38_RS13320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BSF38_RS13325	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSF38_RS13330	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BSF38_RS13355	COG0612	Peptidase, M16
BSF38_RS13360	COG0416	fatty acid biosynthetic process
BSF38_RS13365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSF38_RS13370	COG0367	asparagine synthase
BSF38_RS13405	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS13410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSF38_RS13415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSF38_RS13425	COG1033	growth of symbiont in host cell
BSF38_RS13425	COG2409	Drug exporters of the RND superfamily
BSF38_RS13430	COG1033	growth of symbiont in host cell
BSF38_RS13430	COG2409	Drug exporters of the RND superfamily
BSF38_RS13435	COG0501	Belongs to the peptidase M48B family
BSF38_RS13445	COG1595	DNA-templated transcription, initiation
BSF38_RS13495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSF38_RS13505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSF38_RS13525	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSF38_RS13530	COG0081	regulation of translation
BSF38_RS13535	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BSF38_RS13540	COG0222	ribosome binding
BSF38_RS13545	COG0085	RNA polymerase activity
BSF38_RS13555	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSF38_RS13575	COG1725	Transcriptional regulator
BSF38_RS13580	COG1131	(ABC) transporter
BSF38_RS13590	COG0326	Molecular chaperone. Has ATPase activity
BSF38_RS13615	COG0673	inositol 2-dehydrogenase activity
BSF38_RS13630	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BSF38_RS13650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSF38_RS13660	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BSF38_RS13680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSF38_RS13690	COG2267	carboxylic ester hydrolase activity
BSF38_RS13715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS13725	COG1454	alcohol dehydrogenase
BSF38_RS13740	COG1609	Transcriptional regulator
BSF38_RS13740	COG2207	Transcriptional regulator
BSF38_RS13745	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BSF38_RS13765	COG0643	Histidine kinase
BSF38_RS13765	COG2198	Histidine kinase
BSF38_RS13770	COG3290	protein histidine kinase activity
BSF38_RS13770	COG0840	transmembrane signaling receptor activity
BSF38_RS13780	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSF38_RS13785	COG2201	protein-glutamate methylesterase activity
BSF38_RS13800	COG2271	Major facilitator Superfamily
BSF38_RS13810	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS13815	COG0167	dihydroorotate dehydrogenase activity
BSF38_RS13885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSF38_RS14015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSF38_RS14075	COG0783	Belongs to the Dps family
BSF38_RS14085	COG1741	Belongs to the pirin family
BSF38_RS14120	COG2223	nitrite transmembrane transporter activity
BSF38_RS14140	COG0823	Involved in the tonB-independent uptake of proteins
BSF38_RS14150	COG0039	L-malate dehydrogenase activity
BSF38_RS14155	COG3591	Belongs to the peptidase S1B family
BSF38_RS14165	COG0800	Aldolase
BSF38_RS14190	COG1595	DNA-templated transcription, initiation
BSF38_RS14195	COG0012	GTP binding
BSF38_RS14210	COG2814	Major facilitator Superfamily
BSF38_RS14240	COG1131	(ABC) transporter
BSF38_RS14260	COG0616	signal peptide processing
BSF38_RS14285	COG0300	oxidoreductase activity
BSF38_RS14310	COG0571	ribonuclease III activity
BSF38_RS14325	COG0135	phosphoribosylanthranilate isomerase activity
BSF38_RS14330	COG3118	belongs to the thioredoxin family
BSF38_RS14335	COG0387	Pfam Sodium calcium exchanger
BSF38_RS14350	COG0457	Tetratricopeptide repeat
BSF38_RS14350	COG0463	Glycosyl transferase, family 2
BSF38_RS14360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSF38_RS14370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS14380	COG0367	asparagine synthase
BSF38_RS14385	COG0622	Phosphoesterase
BSF38_RS14390	COG0051	transcription antitermination factor activity, RNA binding
BSF38_RS14395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSF38_RS14400	COG0088	Forms part of the polypeptide exit tunnel
BSF38_RS14405	COG0089	rRNA binding
BSF38_RS14410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSF38_RS14415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSF38_RS14420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BSF38_RS14425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BSF38_RS14430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSF38_RS14435	COG0255	Belongs to the universal ribosomal protein uL29 family
BSF38_RS14440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSF38_RS14445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BSF38_RS14450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BSF38_RS14455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BSF38_RS14460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSF38_RS14465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSF38_RS14470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSF38_RS14475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSF38_RS14480	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSF38_RS14485	COG0200	Binds to the 23S rRNA
BSF38_RS14490	COG0201	protein transport
BSF38_RS14495	COG0024	Methionine aminopeptidase
BSF38_RS14500	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSF38_RS14505	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BSF38_RS14510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BSF38_RS14520	COG0202	RNA polymerase activity
BSF38_RS14525	COG0203	ribosomal protein L17
BSF38_RS14530	COG0537	adenosine 5'-monophosphoramidase activity
BSF38_RS14545	COG2318	DinB family
BSF38_RS14575	COG4453	Protein conserved in bacteria
BSF38_RS14585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS14600	COG5002	protein histidine kinase activity
BSF38_RS14630	COG0430	RNA-3'-phosphate cyclase activity
BSF38_RS14645	COG1733	regulation of RNA biosynthetic process
BSF38_RS14655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSF38_RS14660	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BSF38_RS14665	COG0471	metal ion transport
BSF38_RS14665	COG3273	potassium ion transport
BSF38_RS14680	COG0823	Involved in the tonB-independent uptake of proteins
BSF38_RS14700	COG3119	arylsulfatase activity
BSF38_RS14735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSF38_RS14740	COG0517	IMP dehydrogenase activity
BSF38_RS14740	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BSF38_RS14760	COG1830	Aldolase
BSF38_RS14775	COG1595	DNA-templated transcription, initiation
BSF38_RS14810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BSF38_RS14830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BSF38_RS14910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSF38_RS14920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BSF38_RS14925	COG0038	chloride channel
BSF38_RS14935	COG0367	asparagine synthase
BSF38_RS14945	COG5487	UPF0391 membrane protein
BSF38_RS14955	COG3685	Protein conserved in bacteria
BSF38_RS15005	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BSF38_RS15010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BSF38_RS15040	COG2755	lipolytic protein G-D-S-L family
BSF38_RS15040	COG0657	acetylesterase activity
BSF38_RS15045	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSF38_RS15050	COG4208	sulfate ABC transporter
BSF38_RS15055	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BSF38_RS15060	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BSF38_RS15075	COG3604	Transcriptional regulator
BSF38_RS15100	COG2124	cytochrome p450
BSF38_RS15120	COG4941	Belongs to the sigma-70 factor family
BSF38_RS15145	COG1294	oxidase, subunit
BSF38_RS15150	COG1271	oxidase subunit
BSF38_RS15160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSF38_RS15175	COG3604	Transcriptional regulator
BSF38_RS15215	COG2032	superoxide dismutase activity
BSF38_RS15295	COG0165	Argininosuccinate lyase
BSF38_RS15310	COG2204	response regulator
BSF38_RS15315	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BSF38_RS15345	COG0753	catalase activity
BSF38_RS15355	COG3485	protocatechuate 3,4-dioxygenase
BSF38_RS15440	COG0343	queuine tRNA-ribosyltransferase activity
BSF38_RS15450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSF38_RS15460	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BSF38_RS15470	COG2201	protein-glutamate methylesterase activity
BSF38_RS15475	COG2201	protein-glutamate methylesterase activity
BSF38_RS15505	COG0835	chemotaxis
BSF38_RS15515	COG0840	transmembrane signaling receptor activity
BSF38_RS15525	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSF38_RS15530	COG2198	Histidine kinase
BSF38_RS15530	COG0643	Histidine kinase
BSF38_RS15540	COG1959	2 iron, 2 sulfur cluster binding
BSF38_RS15545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSF38_RS15545	COG1017	nitric oxide dioxygenase activity
BSF38_RS15550	COG1073	alpha beta
BSF38_RS15620	COG4941	Belongs to the sigma-70 factor family
BSF38_RS15625	COG2319	Wd-40 repeat
BSF38_RS15635	COG4191	Histidine kinase
BSF38_RS15650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BSF38_RS15650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BSF38_RS15655	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BSF38_RS15660	COG0288	reversible hydration of carbon dioxide
BSF38_RS15685	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSF38_RS15720	COG0275	rRNA processing
BSF38_RS15765	COG1921	L-seryl-tRNASec selenium transferase activity
BSF38_RS15780	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BSF38_RS15785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSF38_RS15825	COG0667	Aldo Keto reductase
BSF38_RS15845	COG4451	ribulose bisphosphate carboxylase, small
BSF38_RS15845	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BSF38_RS15850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSF38_RS15855	COG0489	protein tyrosine kinase activity
BSF38_RS15880	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BSF38_RS15920	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS15975	COG2076	Multidrug Resistance protein
BSF38_RS16050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BSF38_RS16075	COG1595	DNA-templated transcription, initiation
BSF38_RS16160	COG2010	Cytochrome c
BSF38_RS16170	COG3940	Belongs to the glycosyl hydrolase 43 family
BSF38_RS16225	COG1349	DNA-binding transcription factor activity
BSF38_RS16230	COG2223	nitrite transmembrane transporter activity
BSF38_RS16235	COG0561	phosphatase activity
BSF38_RS16280	COG1606	tRNA processing
BSF38_RS16295	COG1070	Carbohydrate kinase
BSF38_RS16345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSF38_RS16350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSF38_RS16385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSF38_RS16390	COG0187	DNA topoisomerase II activity
BSF38_RS16400	COG0592	DNA-directed DNA polymerase activity
BSF38_RS16425	COG1760	l-serine dehydratase
BSF38_RS16495	COG2815	serine threonine protein kinase
BSF38_RS16495	COG0515	serine threonine protein kinase
BSF38_RS16505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSF38_RS16515	COG0750	zinc metalloprotease
BSF38_RS16520	COG0750	zinc metalloprotease
BSF38_RS16575	COG2610	gluconate transmembrane transporter activity
BSF38_RS16580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BSF38_RS16595	COG1408	metallophosphoesterase
BSF38_RS16640	COG2814	Major facilitator Superfamily
BSF38_RS16680	COG1335	isochorismatase
BSF38_RS16705	COG0753	catalase activity
BSF38_RS16725	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS16730	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS16735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BSF38_RS16745	COG1595	DNA-templated transcription, initiation
BSF38_RS16805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSF38_RS16805	COG2010	Cytochrome c
BSF38_RS16835	COG3258	Cytochrome c
BSF38_RS16910	COG1902	pentaerythritol trinitrate reductase activity
BSF38_RS16965	COG0516	GMP reductase activity
BSF38_RS16965	COG0517	IMP dehydrogenase activity
BSF38_RS16975	COG0704	Plays a role in the regulation of phosphate uptake
BSF38_RS16985	COG0667	Aldo Keto reductase
BSF38_RS17005	COG0307	riboflavin synthase, alpha
BSF38_RS17010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSF38_RS17025	COG3645	SOS response
BSF38_RS17060	COG0793	Belongs to the peptidase S41A family
BSF38_RS17060	COG4946	Tricorn protease homolog
BSF38_RS17070	COG0640	Transcriptional regulator
BSF38_RS17085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BSF38_RS17090	COG2208	phosphoserine phosphatase activity
BSF38_RS17095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSF38_RS17105	COG1595	DNA-templated transcription, initiation
BSF38_RS17135	COG0306	phosphate transporter
BSF38_RS17210	COG2837	iron assimilation
BSF38_RS17245	COG1802	Transcriptional regulator
BSF38_RS17265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS17280	COG1034	ATP synthesis coupled electron transport
BSF38_RS17285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSF38_RS17290	COG3259	Nickel-dependent hydrogenase
BSF38_RS17305	COG4221	oxidoreductase activity
BSF38_RS17345	COG2895	sulfate adenylyltransferase (ATP) activity
BSF38_RS17345	COG0529	Catalyzes the synthesis of activated sulfate
BSF38_RS17350	COG0175	sulfate reduction
BSF38_RS17355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSF38_RS17390	COG4251	negative regulation of phosphorylation
BSF38_RS17395	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BSF38_RS17400	COG0784	Response regulator, receiver
BSF38_RS17400	COG5002	protein histidine kinase activity
BSF38_RS17435	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS17455	COG3459	Glycosyltransferase 36 associated
BSF38_RS17465	COG5265	(ABC) transporter
BSF38_RS17470	COG0750	zinc metalloprotease
BSF38_RS17490	COG2706	6-phosphogluconolactonase activity
BSF38_RS17550	COG2258	MOSC domain
BSF38_RS17580	COG3119	arylsulfatase activity
BSF38_RS17595	COG0483	inositol monophosphate 1-phosphatase activity
BSF38_RS17605	COG1621	beta-fructofuranosidase activity
BSF38_RS17610	COG4806	L-rhamnose isomerase
BSF38_RS17620	COG3250	beta-galactosidase activity
BSF38_RS17660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSF38_RS17675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSF38_RS17695	COG2311	Membrane
BSF38_RS17715	COG1228	amidohydrolase
BSF38_RS17735	COG1515	deoxyribonuclease V activity
BSF38_RS17750	COG1368	sulfuric ester hydrolase activity
BSF38_RS17765	COG5002	protein histidine kinase activity
BSF38_RS17765	COG0784	Response regulator, receiver
BSF38_RS17765	COG2205	protein histidine kinase activity
BSF38_RS17835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSF38_RS17840	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BSF38_RS17845	COG1085	galactose-1-phosphate uridylyltransferase
BSF38_RS17875	COG0148	phosphopyruvate hydratase activity
BSF38_RS17905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSF38_RS17935	COG4717	serine-type aminopeptidase activity
BSF38_RS17940	COG0420	3'-5' exonuclease activity
BSF38_RS17995	COG2208	phosphoserine phosphatase activity
BSF38_RS18025	COG0037	tRNA processing
BSF38_RS18030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSF38_RS18045	COG3386	PFAM SMP-30 Gluconolaconase
BSF38_RS18060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSF38_RS18065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSF38_RS18070	COG0142	geranyltranstransferase activity
BSF38_RS18090	COG1722	exodeoxyribonuclease VII activity
BSF38_RS18110	COG1570	exodeoxyribonuclease VII activity
BSF38_RS18125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSF38_RS18150	COG2239	Acts as a magnesium transporter
BSF38_RS18185	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSF38_RS18195	COG1338	Plays a role in the flagellum-specific transport system
BSF38_RS18200	COG1987	bacterial-type flagellum assembly
BSF38_RS18205	COG1684	flagellar biosynthetic protein fliR
BSF38_RS18215	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSF38_RS18220	COG1419	protein localization to endoplasmic reticulum
BSF38_RS18240	COG0386	Belongs to the glutathione peroxidase family
BSF38_RS18275	COG3119	arylsulfatase activity
BSF38_RS18340	COG0469	pyruvate kinase activity
BSF38_RS18345	COG0673	inositol 2-dehydrogenase activity
BSF38_RS18370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BSF38_RS18375	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSF38_RS18385	COG0673	inositol 2-dehydrogenase activity
BSF38_RS18390	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS18400	COG0180	Tryptophanyl-tRNA synthetase
BSF38_RS18430	COG3064	Membrane
BSF38_RS18430	COG1073	alpha beta
BSF38_RS18430	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BSF38_RS18435	COG2333	competence protein COMEC
BSF38_RS18435	COG0658	competence protein
BSF38_RS18455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSF38_RS18460	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BSF38_RS18465	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSF38_RS18470	COG2815	serine threonine protein kinase
BSF38_RS18470	COG0515	serine threonine protein kinase
BSF38_RS18500	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BSF38_RS18505	COG0714	Associated with various cellular activities
BSF38_RS18525	COG5002	protein histidine kinase activity
BSF38_RS18535	COG5002	protein histidine kinase activity
BSF38_RS18550	COG1776	CheC inhibitor of MCP methylation
BSF38_RS18550	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSF38_RS18560	COG2814	Major facilitator Superfamily
BSF38_RS18600	COG1716	ATPase activity
BSF38_RS18630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSF38_RS18630	COG4797	methyltransferase
BSF38_RS18740	COG1869	D-ribose catabolic process
BSF38_RS18770	COG1012	belongs to the aldehyde dehydrogenase family
BSF38_RS18780	COG0556	nucleotide-excision repair
BSF38_RS18805	COG1797	cobyrinic acid a,c-diamide synthase activity
BSF38_RS18815	COG3264	Mechanosensitive ion channel
BSF38_RS18815	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BSF38_RS18840	COG2017	converts alpha-aldose to the beta-anomer
BSF38_RS18880	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BSF38_RS18885	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BSF38_RS18890	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BSF38_RS18895	COG2205	protein histidine kinase activity
BSF38_RS18900	COG0745	RESPONSE REGULATOR receiver
BSF38_RS18915	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BSF38_RS18960	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSF38_RS18960	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSF38_RS18985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSF38_RS18990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSF38_RS19005	COG0657	acetylesterase activity
BSF38_RS19005	COG2755	lipolytic protein G-D-S-L family
BSF38_RS19020	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BSF38_RS19025	COG0784	Response regulator, receiver
BSF38_RS19025	COG2205	protein histidine kinase activity
BSF38_RS19075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSF38_RS19085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BSF38_RS19090	COG0113	porphobilinogen synthase activity
BSF38_RS19095	COG1530	ribonuclease E activity
BSF38_RS19115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSF38_RS19125	COG1620	l-lactate permease
BSF38_RS19220	COG0745	RESPONSE REGULATOR receiver
BSF38_RS19255	COG2962	Rard protein
BSF38_RS19280	COG0501	Belongs to the peptidase M48B family
BSF38_RS19305	COG2239	Acts as a magnesium transporter
BSF38_RS19310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSF38_RS19315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSF38_RS19355	COG1136	(ABC) transporter
BSF38_RS19390	COG0300	oxidoreductase activity
BSF38_RS19465	COG4948	Mandelate Racemase Muconate Lactonizing
BSF38_RS19540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSF38_RS19555	COG2610	gluconate transmembrane transporter activity
BSF38_RS19575	COG0457	Tetratricopeptide repeat
BSF38_RS19635	COG0436	Aminotransferase
BSF38_RS19640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSF38_RS19670	COG0656	L-ascorbic acid biosynthetic process
BSF38_RS19675	COG0667	Aldo Keto reductase
BSF38_RS19710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSF38_RS19710	COG2080	2 iron, 2 sulfur cluster binding
BSF38_RS19755	COG0776	regulation of translation
BSF38_RS19760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSF38_RS19795	COG0765	amino acid transport
BSF38_RS19800	COG1126	abc transporter atp-binding protein
BSF38_RS19810	COG1595	DNA-templated transcription, initiation
BSF38_RS19815	COG2848	UPF0210 protein
BSF38_RS19825	COG2363	Small membrane protein
BSF38_RS19830	COG0285	dihydrofolate synthase activity
BSF38_RS19835	COG0745	RESPONSE REGULATOR receiver
BSF38_RS19855	COG3119	arylsulfatase activity
BSF38_RS19865	COG0745	RESPONSE REGULATOR receiver
BSF38_RS19875	COG1454	alcohol dehydrogenase
BSF38_RS19915	COG1012	belongs to the aldehyde dehydrogenase family
BSF38_RS19925	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS19945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSF38_RS19955	COG1595	DNA-templated transcription, initiation
BSF38_RS19960	COG0243	molybdopterin cofactor binding
BSF38_RS19990	COG0515	serine threonine protein kinase
BSF38_RS19990	COG2815	serine threonine protein kinase
BSF38_RS20030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSF38_RS20035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSF38_RS20040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BSF38_RS20045	COG0667	Aldo Keto reductase
BSF38_RS20050	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BSF38_RS20055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSF38_RS20060	COG0215	cysteine-tRNA ligase activity
BSF38_RS20065	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BSF38_RS20090	COG2022	thiamine diphosphate biosynthetic process
BSF38_RS20095	COG1199	ATP-dependent helicase activity
BSF38_RS20145	COG1595	DNA-templated transcription, initiation
BSF38_RS20160	COG0107	imidazoleglycerol-phosphate synthase activity
BSF38_RS20170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSF38_RS20190	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSF38_RS20215	COG1477	protein flavinylation
BSF38_RS20220	COG0861	Integral membrane protein TerC family
BSF38_RS20235	COG3119	arylsulfatase activity
BSF38_RS20250	COG1595	DNA-templated transcription, initiation
BSF38_RS20255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSF38_RS20270	COG0457	Tetratricopeptide repeat
BSF38_RS20270	COG0515	serine threonine protein kinase
BSF38_RS20280	COG0396	ATPase activity
BSF38_RS20285	COG0719	Fe-S assembly protein
BSF38_RS20290	COG0719	Fe-S assembly protein
BSF38_RS20295	COG2897	thiosulfate sulfurtransferase activity
BSF38_RS20305	COG0723	plastoquinol--plastocyanin reductase activity
BSF38_RS20320	COG3604	Transcriptional regulator
BSF38_RS20335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSF38_RS20395	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BSF38_RS20400	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BSF38_RS20415	COG1331	Highly conserved protein containing a thioredoxin domain
BSF38_RS20420	COG0793	Belongs to the peptidase S41A family
BSF38_RS20425	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSF38_RS20435	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSF38_RS20440	COG3494	Protein of unknown function (DUF1009)
BSF38_RS20475	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSF38_RS20485	COG5002	protein histidine kinase activity
BSF38_RS20495	COG3279	Response regulator of the LytR AlgR family
BSF38_RS20500	COG2030	dehydratase
BSF38_RS20515	COG1704	LemA family
BSF38_RS20525	COG4112	unkown
BSF38_RS20570	COG3852	Histidine kinase
BSF38_RS20585	COG0328	RNA-DNA hybrid ribonuclease activity
BSF38_RS20590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSF38_RS20595	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSF38_RS20600	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BSF38_RS20640	COG1943	Transposase
BSF38_RS20660	COG2721	sulfolactate sulfo-lyase activity
BSF38_RS20665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSF38_RS20675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSF38_RS20680	COG1459	type II secretion system
BSF38_RS20720	COG0709	Synthesizes selenophosphate from selenide and ATP
BSF38_RS20730	COG0628	permease
BSF38_RS20770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BSF38_RS20775	COG1131	(ABC) transporter
BSF38_RS20805	COG1605	Chorismate mutase
BSF38_RS20805	COG0077	Prephenate dehydratase
BSF38_RS20810	COG0443	Heat shock 70 kDa protein
BSF38_RS20815	COG0542	response to heat
BSF38_RS20855	COG1297	OPT oligopeptide transporter protein
BSF38_RS20860	COG0563	adenylate kinase activity
BSF38_RS20880	COG1674	ftsk spoiiie
BSF38_RS20885	COG1758	RNA polymerase activity
BSF38_RS20890	COG0194	GDP metabolic process
BSF38_RS20895	COG1561	YicC-like family, N-terminal region
BSF38_RS20905	COG0149	triose-phosphate isomerase activity
BSF38_RS20910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BSF38_RS20950	COG2204	response regulator
BSF38_RS20955	COG0515	serine threonine protein kinase
BSF38_RS20955	COG2815	serine threonine protein kinase
BSF38_RS20995	COG3119	arylsulfatase activity
BSF38_RS21000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSF38_RS21025	COG1131	(ABC) transporter
BSF38_RS21095	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS21100	COG4964	Belongs to the GSP D family
BSF38_RS21145	COG4191	Histidine kinase
BSF38_RS21210	COG3361	conserved protein (COG2071)
BSF38_RS21245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSF38_RS21275	COG3119	arylsulfatase activity
BSF38_RS21315	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSF38_RS21320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSF38_RS21340	COG0443	Heat shock 70 kDa protein
BSF38_RS21355	COG0515	serine threonine protein kinase
BSF38_RS21355	COG2815	serine threonine protein kinase
BSF38_RS21365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BSF38_RS21435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSF38_RS21470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSF38_RS21480	COG0617	tRNA 3'-terminal CCA addition
BSF38_RS21520	COG1595	DNA-templated transcription, initiation
BSF38_RS21535	COG0673	inositol 2-dehydrogenase activity
BSF38_RS21555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BSF38_RS21560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSF38_RS21565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSF38_RS21605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSF38_RS21605	COG0519	Catalyzes the synthesis of GMP from XMP
BSF38_RS21620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSF38_RS21625	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BSF38_RS21635	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSF38_RS21640	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BSF38_RS21650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSF38_RS21660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSF38_RS21695	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSF38_RS21700	COG0515	serine threonine protein kinase
BSF38_RS21700	COG2815	serine threonine protein kinase
BSF38_RS21715	COG1643	Atp-dependent helicase
BSF38_RS21730	COG0233	cytoplasmic translational termination
BSF38_RS21735	COG0528	UMP kinase activity
BSF38_RS21740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BSF38_RS21745	COG0052	Belongs to the universal ribosomal protein uS2 family
BSF38_RS21765	COG0346	lactoylglutathione lyase activity
BSF38_RS21785	COG3590	peptidase
BSF38_RS21800	COG0515	serine threonine protein kinase
BSF38_RS21800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSF38_RS21805	COG1477	protein flavinylation
BSF38_RS21815	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSF38_RS21820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSF38_RS21825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BSF38_RS21830	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BSF38_RS21840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSF38_RS21850	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSF38_RS21855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSF38_RS21860	COG1136	(ABC) transporter
BSF38_RS21885	COG2070	2-Nitropropane dioxygenase
BSF38_RS21930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSF38_RS21980	COG1078	dGTPase activity
BSF38_RS21990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BSF38_RS22000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BSF38_RS22010	COG0095	Lipoate-protein ligase
BSF38_RS22020	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSF38_RS22025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSF38_RS22050	COG0586	Pfam SNARE associated Golgi protein
BSF38_RS22060	COG0811	peptide transport
BSF38_RS22070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSF38_RS22090	COG3237	CsbD-like
BSF38_RS22100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSF38_RS22120	COG0277	FAD linked oxidase domain protein
BSF38_RS22130	COG0277	FAD linked oxidase domain protein
BSF38_RS22135	COG0247	lactate metabolic process
BSF38_RS22140	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSF38_RS22160	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSF38_RS22165	COG1234	tRNA 3'-trailer cleavage
BSF38_RS22210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BSF38_RS22220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BSF38_RS22230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSF38_RS22295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSF38_RS22300	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BSF38_RS22305	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSF38_RS22310	COG0300	oxidoreductase activity
BSF38_RS22315	COG2226	methyltransferase
BSF38_RS22335	COG0859	PFAM glycosyl transferase family 9
BSF38_RS22340	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS22350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSF38_RS22385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSF38_RS22395	COG1657	PFAM Prenyltransferase squalene oxidase
BSF38_RS22420	COG2815	serine threonine protein kinase
BSF38_RS22420	COG0515	serine threonine protein kinase
BSF38_RS22435	COG0724	RNA recognition motif
BSF38_RS22445	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BSF38_RS22445	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSF38_RS22450	COG1691	(AIR) carboxylase
BSF38_RS22465	COG1136	(ABC) transporter
BSF38_RS22475	COG0577	efflux transmembrane transporter activity
BSF38_RS22475	COG1136	(ABC) transporter
BSF38_RS22480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BSF38_RS22495	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BSF38_RS22500	COG0298	carbon dioxide binding
BSF38_RS22505	COG0409	Hydrogenase expression formation protein
BSF38_RS22515	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BSF38_RS22550	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BSF38_RS22555	COG0375	protein maturation
BSF38_RS22560	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BSF38_RS22585	COG0745	RESPONSE REGULATOR receiver
BSF38_RS22590	COG5002	protein histidine kinase activity
BSF38_RS22600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSF38_RS22615	COG0039	L-malate dehydrogenase activity
BSF38_RS22620	COG0235	Class ii aldolase
BSF38_RS22645	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BSF38_RS22650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BSF38_RS22655	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BSF38_RS22660	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BSF38_RS22665	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BSF38_RS22670	COG4869	propanediol catabolic process
BSF38_RS22675	COG1349	DNA-binding transcription factor activity
BSF38_RS22680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSF38_RS22690	COG2815	serine threonine protein kinase
BSF38_RS22690	COG0515	serine threonine protein kinase
BSF38_RS22695	COG3253	May function as heme-dependent peroxidase
BSF38_RS22715	COG0424	maF-like protein
BSF38_RS22720	COG0745	RESPONSE REGULATOR receiver
BSF38_RS22750	COG1505	serine-type exopeptidase activity
BSF38_RS22755	COG1960	acyl-CoA dehydrogenase activity
BSF38_RS22770	COG0004	ammonium transporteR
BSF38_RS22780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSF38_RS22790	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BSF38_RS22795	COG0540	Belongs to the ATCase OTCase family
BSF38_RS22800	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSF38_RS22820	COG0045	succinate-CoA ligase (ADP-forming) activity
BSF38_RS22825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BSF38_RS22840	COG0495	leucyl-tRNA aminoacylation
BSF38_RS22845	COG1137	ATPase activity
BSF38_RS22860	COG0481	GTPase activity
BSF38_RS22895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSF38_RS22915	COG1058	Belongs to the CinA family
BSF38_RS22915	COG1546	Belongs to the CinA family
BSF38_RS22930	COG0585	pseudouridine synthase activity
BSF38_RS22935	COG0564	pseudouridine synthase activity
BSF38_RS22970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BSF38_RS22980	COG1073	alpha beta
BSF38_RS22985	COG0859	PFAM glycosyl transferase family 9
BSF38_RS22990	COG0443	Heat shock 70 kDa protein
BSF38_RS22995	COG1073	alpha beta
BSF38_RS23005	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BSF38_RS23030	COG1671	Belongs to the UPF0178 family
BSF38_RS23040	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BSF38_RS23045	COG1404	Belongs to the peptidase S8 family
BSF38_RS23055	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS23060	COG1132	(ABC) transporter
BSF38_RS23070	COG1254	Belongs to the acylphosphatase family
BSF38_RS23080	COG2340	Cysteine-rich secretory protein family
BSF38_RS23090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSF38_RS23105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSF38_RS23130	COG1945	arginine decarboxylase activity
BSF38_RS23135	COG0009	L-threonylcarbamoyladenylate synthase
BSF38_RS23140	COG2255	four-way junction helicase activity
BSF38_RS23145	COG0632	four-way junction helicase activity
BSF38_RS23160	COG1193	negative regulation of DNA recombination
BSF38_RS23170	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BSF38_RS23175	COG4191	Histidine kinase
BSF38_RS23180	COG5564	TIM-barrel signal transduction protein
BSF38_RS23190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSF38_RS23195	COG0318	PFAM AMP-dependent synthetase and ligase
BSF38_RS23200	COG0596	Alpha beta hydrolase
BSF38_RS23205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSF38_RS23210	COG3321	synthase
BSF38_RS23210	COG0604	alcohol dehydrogenase
BSF38_RS23210	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS23215	COG3321	synthase
BSF38_RS23215	COG0604	alcohol dehydrogenase
BSF38_RS23215	COG0604	alcohol dehydrogenase
BSF38_RS23215	COG3321	synthase
BSF38_RS23220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSF38_RS23220	COG2070	2-Nitropropane dioxygenase
BSF38_RS23225	COG2226	methyltransferase
BSF38_RS23230	COG1104	cysteine desulfurase activity
BSF38_RS23235	COG0316	Belongs to the HesB IscA family
BSF38_RS23240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSF38_RS23250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSF38_RS23255	COG0228	four-way junction DNA binding
BSF38_RS23260	COG0336	Belongs to the RNA methyltransferase TrmD family
BSF38_RS23265	COG0335	large ribosomal subunit rRNA binding
BSF38_RS23285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSF38_RS23330	COG3002	Belongs to the UPF0753 family
BSF38_RS23335	COG1007	ATP synthesis coupled electron transport
BSF38_RS23345	COG2890	protein-(glutamine-N5) methyltransferase activity
BSF38_RS23350	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSF38_RS23355	COG0254	rRNA binding
BSF38_RS23365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSF38_RS23390	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSF38_RS23395	COG1129	ABC transporter
BSF38_RS23400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSF38_RS23405	COG1994	Peptidase M50
BSF38_RS23410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSF38_RS23415	COG1879	ABC-type sugar transport system periplasmic component
BSF38_RS23420	COG0667	Aldo Keto reductase
BSF38_RS23435	COG1663	tetraacyldisaccharide 4'-kinase activity
BSF38_RS23440	COG0859	PFAM glycosyl transferase family 9
BSF38_RS23460	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS23465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSF38_RS23470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BSF38_RS23480	COG0477	Major facilitator Superfamily
BSF38_RS23500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSF38_RS23505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSF38_RS23525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSF38_RS23535	COG1459	type II secretion system
BSF38_RS23570	COG4968	Prepilin-type N-terminal cleavage methylation domain
BSF38_RS23615	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS23620	COG2309	aminopeptidase activity
BSF38_RS23650	COG0129	dihydroxy-acid dehydratase activity
BSF38_RS23675	COG2226	methyltransferase
BSF38_RS23675	COG1073	alpha beta
BSF38_RS23680	COG1045	serine acetyltransferase
BSF38_RS23710	COG0101	tRNA pseudouridine synthase activity
BSF38_RS23715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BSF38_RS23720	COG0151	Belongs to the GarS family
BSF38_RS23845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSF38_RS23865	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BSF38_RS23870	COG1518	maintenance of DNA repeat elements
BSF38_RS23935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSF38_RS24010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSF38_RS24015	COG1032	radical SAM domain protein
BSF38_RS24100	COG0473	3-isopropylmalate dehydrogenase activity
BSF38_RS24105	COG2815	serine threonine protein kinase
BSF38_RS24105	COG0515	serine threonine protein kinase
BSF38_RS24120	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSF38_RS24125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BSF38_RS24130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSF38_RS24145	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BSF38_RS24185	COG0129	dihydroxy-acid dehydratase activity
BSF38_RS24230	COG3383	formate dehydrogenase (NAD+) activity
BSF38_RS24245	COG1595	DNA-templated transcription, initiation
BSF38_RS24250	COG1595	DNA-templated transcription, initiation
BSF38_RS24260	COG2204	response regulator
BSF38_RS24280	COG0714	Associated with various cellular activities
BSF38_RS24330	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BSF38_RS24340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSF38_RS24375	COG1185	polyribonucleotide nucleotidyltransferase activity
BSF38_RS24380	COG4191	Histidine kinase
BSF38_RS24385	COG2204	response regulator
BSF38_RS24405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSF38_RS24410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BSF38_RS24415	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BSF38_RS24430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSF38_RS24440	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSF38_RS24445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSF38_RS24460	COG2814	Major facilitator Superfamily
BSF38_RS24480	COG0646	methionine synthase
BSF38_RS24480	COG1410	methionine synthase
BSF38_RS24490	COG3386	PFAM SMP-30 Gluconolaconase
BSF38_RS24500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BSF38_RS24505	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
BSF38_RS24520	COG4302	ethanolamine ammonia-lyase activity
BSF38_RS24530	COG4303	Ethanolamine ammonia lyase large subunit
BSF38_RS24540	COG0018	arginyl-trna synthetase
BSF38_RS24545	COG0799	negative regulation of ribosome biogenesis
BSF38_RS24560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSF38_RS24565	COG1640	4-alpha-glucanotransferase
BSF38_RS24570	COG0517	IMP dehydrogenase activity
BSF38_RS24570	COG0516	GMP reductase activity
BSF38_RS24580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSF38_RS24585	COG2154	pterin-4-alpha-carbinolamine dehydratase
BSF38_RS24610	COG1132	(ABC) transporter
BSF38_RS24665	COG3293	Transposase
BSF38_RS24680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSF38_RS24690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSF38_RS24705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BSF38_RS24725	COG2081	HI0933 family
BSF38_RS24730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSF38_RS24740	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BSF38_RS24745	COG1929	Belongs to the glycerate kinase type-1 family
BSF38_RS24760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BSF38_RS24780	COG0539	negative regulation of cytoplasmic translation
BSF38_RS24785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BSF38_RS24795	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BSF38_RS24800	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BSF38_RS24815	COG1595	DNA-templated transcription, initiation
BSF38_RS24830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BSF38_RS24840	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BSF38_RS24865	COG1449	Belongs to the glycosyl hydrolase 57 family
BSF38_RS24880	COG0297	glycogen (starch) synthase activity
BSF38_RS24885	COG4712	double-strand break repair protein
BSF38_RS24905	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BSF38_RS24915	COG0512	Glutamine amidotransferase of anthranilate synthase
BSF38_RS24915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSF38_RS24925	COG1131	(ABC) transporter
BSF38_RS24940	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BSF38_RS24975	COG3119	arylsulfatase activity
BSF38_RS24995	COG0148	phosphopyruvate hydratase activity
BSF38_RS25000	COG1595	DNA-templated transcription, initiation
BSF38_RS25010	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BSF38_RS25015	COG2208	phosphoserine phosphatase activity
BSF38_RS25040	COG1025	Belongs to the peptidase M16 family
BSF38_RS25050	COG0626	cystathionine gamma-synthase activity
BSF38_RS25055	COG0384	phenazine biosynthesis protein PhzF
BSF38_RS25065	COG1131	(ABC) transporter
BSF38_RS25120	COG0450	alkyl hydroperoxide reductase
BSF38_RS25125	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSF38_RS25125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSF38_RS25130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSF38_RS25155	COG1566	PFAM secretion protein HlyD family protein
BSF38_RS25160	COG1073	alpha beta
BSF38_RS25165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSF38_RS25200	COG5002	protein histidine kinase activity
BSF38_RS25225	COG0424	maF-like protein
BSF38_RS25265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSF38_RS25295	COG0606	chelatase, subunit chli
BSF38_RS25550	COG1253	flavin adenine dinucleotide binding
BSF38_RS25570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSF38_RS25595	COG0473	3-isopropylmalate dehydrogenase activity
BSF38_RS25615	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BSF38_RS25640	COG2271	Major facilitator Superfamily
BSF38_RS25645	COG3534	alpha-L-arabinofuranosidase
BSF38_RS25660	COG1774	PSP1 C-terminal conserved region
BSF38_RS25675	COG2835	tetraacyldisaccharide 4'-kinase activity
BSF38_RS25745	COG0702	epimerase
BSF38_RS25760	COG0463	Glycosyl transferase, family 2
BSF38_RS25770	COG1233	COG1233 Phytoene dehydrogenase and related
BSF38_RS25800	COG0515	serine threonine protein kinase
BSF38_RS25800	COG2815	serine threonine protein kinase
BSF38_RS25810	COG2766	serine protein kinase
BSF38_RS25815	COG2718	Belongs to the UPF0229 family
BSF38_RS25825	COG2719	SpoVR family
BSF38_RS25855	COG0205	6-phosphofructokinase activity
BSF38_RS25865	COG4152	abc transporter atp-binding protein
BSF38_RS25925	COG1136	(ABC) transporter
BSF38_RS25930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSF38_RS25940	COG0386	Belongs to the glutathione peroxidase family
BSF38_RS25945	COG0352	thiamine-phosphate diphosphorylase activity
BSF38_RS25950	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BSF38_RS25970	COG3118	belongs to the thioredoxin family
BSF38_RS25995	COG0515	serine threonine protein kinase
BSF38_RS26000	COG0545	Peptidyl-prolyl cis-trans isomerase
BSF38_RS26005	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BSF38_RS26010	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS26020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSF38_RS26050	COG0673	inositol 2-dehydrogenase activity
BSF38_RS26055	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSF38_RS26060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSF38_RS26060	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BSF38_RS26075	COG0640	Transcriptional regulator
BSF38_RS26080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSF38_RS26085	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BSF38_RS26090	COG0210	DNA helicase
BSF38_RS26095	COG0736	holo-[acyl-carrier-protein] synthase activity
BSF38_RS26100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSF38_RS26125	COG1160	GTP binding
BSF38_RS26135	COG0784	Response regulator, receiver
BSF38_RS26135	COG2205	protein histidine kinase activity
BSF38_RS26160	COG0686	Belongs to the AlaDH PNT family
BSF38_RS26170	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BSF38_RS26195	COG0300	oxidoreductase activity
BSF38_RS26200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSF38_RS26210	COG0156	8-amino-7-oxononanoate synthase activity
BSF38_RS26270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSF38_RS26275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSF38_RS26285	COG3119	arylsulfatase activity
BSF38_RS26295	COG1595	DNA-templated transcription, initiation
BSF38_RS26300	COG2808	Putative FMN-binding domain
BSF38_RS26305	COG0217	transcriptional regulatory protein
BSF38_RS26315	COG0667	Aldo Keto reductase
BSF38_RS26320	COG1595	DNA-templated transcription, initiation
BSF38_RS26330	COG3682	Transcriptional regulator
BSF38_RS26355	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSF38_RS26360	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSF38_RS26365	COG0195	Participates in both transcription termination and antitermination
BSF38_RS26365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSF38_RS26375	COG0084	hydrolase, TatD family'
BSF38_RS26395	COG0602	queuosine metabolic process
BSF38_RS26405	COG0515	serine threonine protein kinase
BSF38_RS26405	COG2815	serine threonine protein kinase
BSF38_RS26415	COG3240	lipase activity
BSF38_RS26455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSF38_RS26490	COG1595	DNA-templated transcription, initiation
BSF38_RS26555	COG3119	arylsulfatase activity
BSF38_RS26565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSF38_RS26580	COG0745	RESPONSE REGULATOR receiver
BSF38_RS26585	COG5002	protein histidine kinase activity
BSF38_RS26600	COG0463	Glycosyl transferase, family 2
BSF38_RS26610	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BSF38_RS26625	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BSF38_RS26625	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BSF38_RS26630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BSF38_RS26655	COG0484	heat shock protein binding
BSF38_RS26670	COG0594	ribonuclease P activity
BSF38_RS26675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BSF38_RS26750	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS26780	COG3059	membrane
BSF38_RS26785	COG2207	Transcriptional regulator
BSF38_RS26785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSF38_RS26815	COG0714	Associated with various cellular activities
BSF38_RS26835	COG0415	Belongs to the DNA photolyase family
BSF38_RS26910	COG2045	Belongs to the ComB family
BSF38_RS26915	COG0423	glycine-tRNA ligase activity
BSF38_RS26940	COG3386	PFAM SMP-30 Gluconolaconase
BSF38_RS26955	COG0714	Associated with various cellular activities
BSF38_RS26990	COG0659	secondary active sulfate transmembrane transporter activity
BSF38_RS27005	COG3293	Transposase
BSF38_RS27050	COG2267	carboxylic ester hydrolase activity
BSF38_RS27070	COG2514	catechol 2,3-dioxygenase activity
BSF38_RS27085	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BSF38_RS27090	COG1881	PFAM PEBP family protein
BSF38_RS27155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSF38_RS27170	COG2205	protein histidine kinase activity
BSF38_RS27175	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS27240	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BSF38_RS27245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSF38_RS27255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BSF38_RS27275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSF38_RS27295	COG1657	PFAM Prenyltransferase squalene oxidase
BSF38_RS27300	COG0531	amino acid
BSF38_RS27315	COG0131	Imidazoleglycerol-phosphate dehydratase
BSF38_RS27320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSF38_RS27330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSF38_RS27370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSF38_RS27380	COG1028	Short-chain dehydrogenase reductase Sdr
BSF38_RS27395	COG0538	isocitrate dehydrogenase activity
BSF38_RS27440	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BSF38_RS27470	COG1506	peptidase
BSF38_RS27470	COG0823	Involved in the tonB-independent uptake of proteins
BSF38_RS27475	COG3104	oligopeptide transport
BSF38_RS27485	COG0432	Pfam Uncharacterised protein family UPF0047
BSF38_RS27495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSF38_RS27500	COG0322	excinuclease ABC activity
BSF38_RS27505	COG3458	cephalosporin-C deacetylase activity
BSF38_RS27515	COG0488	(ABC) transporter
BSF38_RS27525	COG0640	Transcriptional regulator
BSF38_RS27570	COG2154	pterin-4-alpha-carbinolamine dehydratase
BSF38_RS27580	COG0531	amino acid
BSF38_RS27590	COG3876	Protein conserved in bacteria
BSF38_RS27615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BSF38_RS27620	COG1872	DUF167
BSF38_RS27625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSF38_RS27635	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSF38_RS27675	COG0459	protein refolding
BSF38_RS27680	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSF38_RS27685	COG0459	protein refolding
BSF38_RS27690	COG0484	heat shock protein binding
BSF38_RS27695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BSF38_RS27705	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BSF38_RS27715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSF38_RS27720	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSF38_RS27725	COG0022	dehydrogenase e1 component
BSF38_RS27725	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSF38_RS27730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSF38_RS27740	COG4191	Histidine kinase
BSF38_RS27780	COG0714	Associated with various cellular activities
BSF38_RS27810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSF38_RS27815	COG0723	plastoquinol--plastocyanin reductase activity
BSF38_RS27830	COG2271	Major facilitator Superfamily
BSF38_RS27845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSF38_RS27855	COG0366	Alpha amylase catalytic
BSF38_RS27870	COG3293	Transposase
BSF38_RS27910	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BSF38_RS27915	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BSF38_RS27935	COG2337	Toxic component of a toxin-antitoxin (TA) module
BSF38_RS27945	COG1940	carbohydrate kinase activity
BSF38_RS27950	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BSF38_RS27985	COG1131	(ABC) transporter
BSF38_RS28000	COG0440	acetolactate synthase activity
BSF38_RS28005	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSF38_RS28045	COG0626	cystathionine gamma-synthase activity
BSF38_RS28055	COG1834	amidinotransferase
BSF38_RS28070	COG2204	response regulator
BSF38_RS28075	COG5002	protein histidine kinase activity
BSF38_RS28090	COG0673	inositol 2-dehydrogenase activity
BSF38_RS28100	COG2140	Oxalate decarboxylase
BSF38_RS28110	COG1119	ATPase activity
BSF38_RS28120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSF38_RS28130	COG1408	metallophosphoesterase
BSF38_RS28135	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS28145	COG1216	Glycosyl transferase, family 2
BSF38_RS28150	COG1960	acyl-CoA dehydrogenase activity
BSF38_RS28160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSF38_RS28165	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSF38_RS28170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSF38_RS28200	COG0811	peptide transport
BSF38_RS28225	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSF38_RS28230	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSF38_RS28265	COG0204	Acyl-transferase
BSF38_RS28265	COG0318	PFAM AMP-dependent synthetase and ligase
BSF38_RS28275	COG0287	Prephenate dehydrogenase
BSF38_RS28280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSF38_RS28290	COG0047	phosphoribosylformylglycinamidine synthase activity
BSF38_RS28315	COG2066	Belongs to the glutaminase family
BSF38_RS28320	COG2088	sporulation resulting in formation of a cellular spore
BSF38_RS28325	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BSF38_RS28365	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BSF38_RS28410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSF38_RS28415	COG0613	PHP domain protein
BSF38_RS28420	COG0552	protein localization to endoplasmic reticulum
BSF38_RS28455	COG0275	rRNA processing
BSF38_RS28465	COG0515	serine threonine protein kinase
BSF38_RS28465	COG2815	serine threonine protein kinase
BSF38_RS28490	COG0667	Aldo Keto reductase
BSF38_RS28495	COG1064	alcohol dehydrogenase
BSF38_RS28500	COG2207	Transcriptional regulator
BSF38_RS28525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSF38_RS28555	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS28570	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BSF38_RS28575	COG1450	Type ii and iii secretion system protein
BSF38_RS28605	COG1459	type II secretion system
BSF38_RS28610	COG4968	Prepilin-type N-terminal cleavage methylation domain
BSF38_RS28690	COG2340	Cysteine-rich secretory protein family
BSF38_RS28705	COG2815	serine threonine protein kinase
BSF38_RS28705	COG0515	serine threonine protein kinase
BSF38_RS28725	COG0515	serine threonine protein kinase
BSF38_RS28725	COG2815	serine threonine protein kinase
BSF38_RS28745	COG0181	hydroxymethylbilane synthase activity
BSF38_RS28750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSF38_RS28760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSF38_RS28770	COG2326	polyphosphate kinase activity
BSF38_RS28790	COG0535	radical SAM domain protein
BSF38_RS28795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSF38_RS28835	COG1129	ABC transporter
BSF38_RS28840	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSF38_RS28850	COG0438	transferase activity, transferring glycosyl groups
BSF38_RS28865	COG1764	response to oxidative stress
BSF38_RS28900	COG0321	lipoyl(octanoyl) transferase activity
BSF38_RS28905	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BSF38_RS28910	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSF38_RS28915	COG0066	3-isopropylmalate dehydratase activity
BSF38_RS28925	COG0175	sulfate reduction
BSF38_RS28935	COG2046	Belongs to the sulfate adenylyltransferase family
BSF38_RS28935	COG0529	Catalyzes the synthesis of activated sulfate
BSF38_RS28940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSF38_RS28945	COG0640	Transcriptional regulator
BSF38_RS28955	COG2226	methyltransferase
BSF38_RS28985	COG0596	Alpha beta hydrolase
BSF38_RS29050	COG1192	Involved in chromosome partitioning
BSF38_RS29200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSF38_RS29500	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification